| Year |
Citation |
Score |
| 2022 |
Xu W, Dahlke SP, Sung M, Samal B, Emery AC, Elkahloun A, Eiden LE. ERK-dependent induction of the immediate-early gene Egr1 and the late gene Gpr50 contribute to two distinct phases of PACAP Gs-GPCR signaling for neuritogenesis. Journal of Neuroendocrinology. e13182. PMID 35841324 DOI: 10.1111/jne.13182 |
0.345 |
|
| 2021 |
Xu W, Dahlke SP, Emery AC, Sung M, Chepurny OG, Holz GG, Eiden LE. Cyclic AMP-dependent activation of ERK via GLP-1 receptor signalling requires the neuroendocrine cell-specific guanine nucleotide exchanger NCS-RapGEF2. Journal of Neuroendocrinology. e12974. PMID 33960038 DOI: 10.1111/jne.12974 |
0.55 |
|
| 2020 |
Eiden LE, Emery AC, Dahlke S, Xu W. Persistence of Cyclic AMP Signaling Determines Gs‐couple GPCR Linkage to ERK Activation The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.07141 |
0.658 |
|
| 2017 |
Jiang SZ, Xu W, Emery AC, Gerfen CR, Eiden MV, Eiden LE. NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. Eneuro. 4. PMID 28948210 DOI: 10.1523/ENEURO.0248-17.2017 |
0.393 |
|
| 2017 |
Emery AC, Xu W, Eiden MV, Eiden LE. Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells. The Journal of Biological Chemistry. PMID 28546426 DOI: 10.1074/jbc.M117.790329 |
0.464 |
|
| 2017 |
Emery AC, Alvarez RA, Eiden MV, Xu W, Simeon FG, Eiden LE. Differential Pharmacophore Definition of the cAMP Binding Sites of NCS-Rapgef2, PKA and Epac in Neuroendocrine Cells Using an Adenine-based Scaffold. Acs Chemical Neuroscience. PMID 28290664 DOI: 10.1021/acschemneuro.6b00462 |
0.44 |
|
| 2016 |
Emery AC, Alvarez RA, Abboud P, Xu W, Westover CD, Eiden MV, Eiden LE. C-terminal amidation of PACAP-38 and PACAP-27 is dispensable for biological activity at the PAC1 receptor. Peptides. PMID 26976270 DOI: 10.1016/j.peptides.2016.03.003 |
0.539 |
|
| 2016 |
Emery AC, Eiden MV, Eiden LE. Evaluating the Specificity and Potency of Activators and Inhibitors of the cAMP Sensors PKA, Epac2/Rapgef4, and NCS/Rapgef2 Using Cell-Based Assays for Activation of CREB, p38 MAPK, and ERK The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.1190.9 |
0.39 |
|
| 2015 |
Emery AC, Liu XH, Xu W, Eiden MV, Eiden LE. Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform. Molecular Pharmacology. 87: 928-35. PMID 25769305 DOI: 10.1124/mol.115.098087 |
0.712 |
|
| 2015 |
Hathaway HA, Pshenichkin S, Grajkowska E, Gelb T, Emery AC, Wolfe BB, Wroblewski JT. Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism. Neuropharmacology. 93: 199-208. PMID 25700650 DOI: 10.1016/J.Neuropharm.2015.02.007 |
0.753 |
|
| 2014 |
Emery AC, Eiden MV, Eiden LE. Separate cyclic AMP sensors for neuritogenesis, growth arrest, and survival of neuroendocrine cells. The Journal of Biological Chemistry. 289: 10126-39. PMID 24567337 DOI: 10.1074/jbc.M113.529321 |
0.715 |
|
| 2013 |
Emery AC. Catecholamine receptors: prototypes for GPCR-based drug discovery. Advances in Pharmacology (San Diego, Calif.). 68: 335-56. PMID 24054152 DOI: 10.1016/B978-0-12-411512-5.00016-6 |
0.303 |
|
| 2013 |
Emery AC, Eiden MV, Mustafa T, Eiden LE. Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. Science Signaling. 6: ra51. PMID 23800469 DOI: 10.1126/scisignal.2003993 |
0.699 |
|
| 2013 |
Emery AC, Eiden MV, Eiden LE. A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536. Molecular Pharmacology. 83: 95-105. PMID 23053667 DOI: 10.1124/mol.112.081760 |
0.656 |
|
| 2013 |
Emery AC, Eiden LE. Novel cAMP Sensor Links GPCR-Gs Signaling to ERK in Neuroscreen-1 Cells Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 114. DOI: 10.1016/B978-0-12-800044-1.00100-8 |
0.603 |
|
| 2012 |
Emery AC, DiRaddo JO, Miller E, Hathaway HA, Pshenichkin S, Takoudjou GR, Grajkowska E, Yasuda RP, Wolfe BB, Wroblewski JT. Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling. Molecular Pharmacology. 82: 291-301. PMID 22584219 DOI: 10.1124/Mol.112.078444 |
0.546 |
|
| 2012 |
Emery AC, Eiden LE. Signaling through the neuropeptide GPCR PACâ‚ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3199-211. PMID 22532442 DOI: 10.1096/fj.11-203042 |
0.645 |
|
| 2010 |
Emery AC, Pshenichkin S, Takoudjou GR, Grajkowska E, Wolfe BB, Wroblewski JT. The protective signaling of metabotropic glutamate receptor 1 Is mediated by sustained, beta-arrestin-1-dependent ERK phosphorylation. The Journal of Biological Chemistry. 285: 26041-8. PMID 20566651 DOI: 10.1074/jbc.M110.139899 |
0.714 |
|
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