Claire Thornton - Publications

Affiliations: 
Imperial College, London, London, England, United Kingdom 
Area:
Signalling, neurodegeneration

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bingor A, Haham T, Thornton C, Stern-Bach Y, Yaka R. Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors. Nature Communications. 11: 3688. PMID 32703948 DOI: 10.1038/s41467-020-17484-y  0.64
2020 Bingor A, Haham T, Thornton C, Stern-Bach Y, Yaka R. Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors. Nature Communications. 11: 3688. PMID 32703948 DOI: 10.1038/s41467-020-17484-y  0.52
2020 Bingor A, Haham T, Thornton C, Stern-Bach Y, Yaka R. Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors. Nature Communications. 11: 3688. PMID 32703948 DOI: 10.1038/s41467-020-17484-y  0.76
2020 Poupon-Bejuit L, Rocha-Ferreira E, Thornton C, Hagberg H, Rahim AA. Neuroprotective Effects of Diabetes Drugs for the Treatment of Neonatal Hypoxia-Ischemia Encephalopathy. Frontiers in Cellular Neuroscience. 14: 112. PMID 32435185 DOI: 10.3389/fncel.2020.00112  0.52
2019 Stolp HB, Fleiss B, Arai Y, Supramaniam V, Vontell R, Birtles S, Yates AG, Baburamani AA, Thornton C, Rutherford M, Edwards AD, Gressens P. Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human. Frontiers in Physiology. 10: 955. PMID 31417418 DOI: 10.3389/fphys.2019.00955  0.52
2019 Nair S, Sobotka KS, Joshi P, Gressens P, Fleiss B, Thornton C, Mallard C, Hagberg H. Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo. Glia. PMID 30637805 DOI: 10.1002/glia.23587  0.52
2018 Rocha-Ferreira E, Poupon L, Zelco A, Leverin AL, Nair S, Jonsdotter A, Carlsson Y, Thornton C, Hagberg H, Rahim AA. Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy. Brain : a Journal of Neurology. PMID 30165597 DOI: 10.1093/brain/awy220  0.52
2018 Kichev A, Baburamani AA, Vontell R, Gressens P, Burkly L, Thornton C, Hagberg H. TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia. Frontiers in Neurology. 9: 230. PMID 29706927 DOI: 10.3389/fneur.2018.00230  0.52
2018 Koning G, Lyngfelt E, Svedin P, Leverin AL, Jinnai M, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H. Magnesium sulphate induces preconditioning in preterm rodent models of cerebral hypoxia-ischemia. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 29355709 DOI: 10.1016/j.ijdevneu.2018.01.002  0.52
2017 Thornton C, Jones A, Nair S, Aabdien A, Mallard C, Hagberg H. Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury. Febs Letters. PMID 29265370 DOI: 10.1002/1873-3468.12943  0.52
2017 Zhang X, Rocha-Ferreira E, Li T, Vontell R, Jabin D, Hua S, Zhou K, Nazmi A, Albertsson AM, Sobotka K, Ek J, Thornton C, Hagberg H, Mallard C, Leavenworth JW, et al. γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice. Journal of Neuroinflammation. 14: 255. PMID 29262837 DOI: 10.1186/s12974-017-1029-9  0.52
2017 Koning G, Leverin AL, Nair S, Schwendimann L, Ek J, Carlsson Y, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H. Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17746132. PMID 29206066 DOI: 10.1177/0271678X17746132  0.52
2017 Thornton C, Baburamani AA, Kichev A, Hagberg H. Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury. Biochemical Society Transactions. PMID 28939695 DOI: 10.1042/BST20170017  0.52
2017 Thornton C, Leaw B, Mallard C, Nair S, Jinnai M, Hagberg H. Cell Death in the Developing Brain after Hypoxia-Ischemia. Frontiers in Cellular Neuroscience. 11: 248. PMID 28878624 DOI: 10.3389/fncel.2017.00248  0.52
2017 Leaw B, Nair S, Lim R, Thornton C, Mallard C, Hagberg H. Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury. Frontiers in Cellular Neuroscience. 11: 199. PMID 28747873 DOI: 10.3389/fncel.2017.00199  0.52
2017 Kichev A, Eede P, Gressens P, Thornton C, Hagberg H. Implicating Receptor Activator of NF-κB (RANK)/RANK Ligand Signalling in Microglial Responses to Toll-Like Receptor Stimuli. Developmental Neuroscience. PMID 28402971 DOI: 10.1159/000464244  0.52
2017 Baburamani AA, Sobotka KS, Vontell R, Mallard C, Supramaniam VG, Thornton C, Hagberg H. Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia. Oncotarget. PMID 28076846 DOI: 10.18632/oncotarget.14518  0.52
2015 Baburamani AA, Hurling C, Stolp H, Sobotka K, Gressens P, Hagberg H, Thornton C. Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury. International Journal of Molecular Sciences. 16: 22509-26. PMID 26393574 DOI: 10.3390/ijms160922509  1
2015 Fang X, Corrales J, Thornton C, Clerk T, Scheffler BE, Willett KL. Transcriptomic Changes in Zebrafish Embryos and Larvae Following Benzo[a]pyrene Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 146: 395-411. PMID 26001963 DOI: 10.1093/toxsci/kfv105  0.44
2015 Baburamani AA, Miyakuni Y, Vontell R, Supramaniam VG, Svedin P, Rutherford M, Gressens P, Mallard C, Takeda S, Thornton C, Hagberg H. Does Caspase-6 Have a Role in Perinatal Brain Injury? Developmental Neuroscience. PMID 25823427 DOI: 10.1159/000375368  1
2015 Hawkins AD, Thornton C, Kennedy AJ, Bu K, Cizdziel J, Jones BW, Steevens JA, Willett KL. Gill histopathologies following exposure to nanosilver or silver nitrate. Journal of Toxicology and Environmental Health. Part A. 78: 301-15. PMID 25734626 DOI: 10.1080/15287394.2014.971386  0.44
2015 Fleiss B, Chhor V, Rajudin N, Lebon S, Hagberg H, Gressens P, Thornton C. The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia. Developmental Neuroscience. PMID 25721106 DOI: 10.1159/000370031  1
2015 Vontell R, Supramaniam V, Wyatt-Ashmead J, Gressens P, Rutherford M, Hagberg H, Thornton C. Cellular mechanisms of toll-like receptor-3 activation in the thalamus are associated with white matter injury in the developing brain. Journal of Neuropathology and Experimental Neurology. 74: 273-85. PMID 25668563 DOI: 10.1097/NEN.0000000000000172  1
2015 Thornton C, Hagberg H. Role of mitochondria in apoptotic and necroptotic cell death in the developing brain. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 25661091 DOI: 10.1016/j.cca.2015.01.026  1
2015 Rousset CI, Leiper FC, Kichev A, Gressens P, Carling D, Hagberg H, Thornton C. A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry. 133: 242-52. PMID 25598140 DOI: 10.1111/jnc.13034  1
2015 Garcia-Reyero N, Thornton C, Hawkins AD, Escalon L, Kennedy AJ, Steevens JA, Willett KL. Assessing the exposure to nanosilver and silver nitrate on fathead minnow gill gene expression and mucus production Environmental Nanotechnology, Monitoring and Management. 4: 58-66. DOI: 10.1016/j.enmm.2015.06.001  0.44
2014 Hawkins AD, Thornton C, Steevens JA, Willett KL. Alteration in Pimephales promelas mucus production after exposure to nanosilver or silver nitrate. Environmental Toxicology and Chemistry / Setac. 33: 2869-72. PMID 25262928 DOI: 10.1002/etc.2759  0.44
2014 Booc F, Thornton C, Lister A, MacLatchy D, Willett KL. Benzo[a]pyrene effects on reproductive endpoints in Fundulus heteroclitus. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 73-82. PMID 24747980 DOI: 10.1093/toxsci/kfu064  0.44
2014 Corrales J, Fang X, Thornton C, Mei W, Barbazuk WB, Duke M, Scheffler BE, Willett KL. Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo[a]pyrene exposure. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 163: 37-46. PMID 24576477 DOI: 10.1016/j.cbpc.2014.02.005  0.44
2014 Kichev A, Rousset CI, Baburamani AA, Levison SW, Wood TL, Gressens P, Thornton C, Hagberg H. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) signaling and cell death in the immature central nervous system after hypoxia-ischemia and inflammation. The Journal of Biological Chemistry. 289: 9430-9. PMID 24509861 DOI: 10.1074/jbc.M113.512350  1
2014 Hagberg H, Mallard C, Rousset CI, Thornton C. Mitochondria: hub of injury responses in the developing brain. The Lancet. Neurology. 13: 217-32. PMID 24457191 DOI: 10.1016/S1474-4422(13)70261-8  1
2014 Corrales J, Thornton C, White M, Willett KL. Multigenerational effects of benzo[a]pyrene exposure on survival and developmental deformities in zebrafish larvae. Aquatic Toxicology (Amsterdam, Netherlands). 148: 16-26. PMID 24440964 DOI: 10.1016/j.aquatox.2013.12.028  0.44
2013 Nair S, Hagberg H, Krishnamurthy R, Thornton C, Mallard C. Death associated protein kinases: molecular structure and brain injury. International Journal of Molecular Sciences. 14: 13858-72. PMID 23880846 DOI: 10.3390/ijms140713858  1
2013 Fang X, Corrales J, Thornton C, Scheffler BE, Willett KL. Global and gene specific DNA methylation changes during zebrafish development. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 166: 99-108. PMID 23876386 DOI: 10.1016/j.cbpb.2013.07.007  0.44
2013 Järlestedt K, Rousset CI, StÃ¥hlberg A, Sourkova H, Atkins AL, Thornton C, Barnum SR, Wetsel RA, Dragunow M, Pekny M, Mallard C, Hagberg H, Pekna M. Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3797-804. PMID 23737250 DOI: 10.1096/fj.13-230011  1
2013 Vontell R, Supramaniam V, Thornton C, Wyatt-Ashmead J, Mallard C, Gressens P, Rutherford M, Hagberg H. Toll-like receptor 3 expression in glia and neurons alters in response to white matter injury in preterm infants. Developmental Neuroscience. 35: 130-9. PMID 23548575 DOI: 10.1159/000346158  1
2013 Fang X, Thornton C, Scheffler BE, Willett KL. Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish development. Environmental Toxicology and Pharmacology. 36: 40-50. PMID 23542452 DOI: 10.1016/j.etap.2013.02.014  0.44
2012 Carling D, Thornton C, Woods A, Sanders MJ. AMP-activated protein kinase: new regulation, new roles? The Biochemical Journal. 445: 11-27. PMID 22702974 DOI: 10.1042/BJ20120546  1
2012 Thornton C, Rousset CI, Kichev A, Miyakuni Y, Vontell R, Baburamani AA, Fleiss B, Gressens P, Hagberg H. Molecular mechanisms of neonatal brain injury. Neurology Research International. 2012: 506320. PMID 22363841 DOI: 10.1155/2012/506320  1
2012 Rousset CI, Baburamani AA, Thornton C, Hagberg H. Mitochondria and perinatal brain injury. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 25: 35-8. PMID 22348594 DOI: 10.3109/14767058.2012.666398  1
2011 Thornton C, Bright NJ, Sastre M, Muckett PJ, Carling D. AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure. The Biochemical Journal. 434: 503-12. PMID 21204788 DOI: 10.1042/BJ20101485  1
2010 Wang L, Camus AC, Dong W, Thornton C, Willett KL. Expression of CYP1C1 and CYP1A in Fundulus heteroclitus during PAH-induced carcinogenesis. Aquatic Toxicology (Amsterdam, Netherlands). 99: 439-47. PMID 20621368 DOI: 10.1016/j.aquatox.2010.06.002  0.44
2010 Scornaienchi ML, Thornton C, Willett KL, Wilson JY. Functional differences in the cytochrome P450 1 family enzymes from zebrafish (Danio rerio) using heterologously expressed proteins. Archives of Biochemistry and Biophysics. 502: 17-22. PMID 20599672 DOI: 10.1016/j.abb.2010.06.018  0.44
2010 Scornaienchi ML, Thornton C, Willett KL, Wilson JY. Cytochrome P450-mediated 17beta-estradiol metabolism in zebrafish (Danio rerio). The Journal of Endocrinology. 206: 317-25. PMID 20522564 DOI: 10.1677/JOE-10-0075  0.44
2010 Fang X, Dong W, Thornton C, Willett KL. Benzo[a]pyrene effects on glycine N-methyltransferase mRNA expression and enzyme activity in Fundulus heteroclitus embryos. Aquatic Toxicology (Amsterdam, Netherlands). 98: 130-8. PMID 20185185 DOI: 10.1016/j.aquatox.2010.02.004  0.44
2010 Fang X, Dong W, Thornton C, Scheffler B, Willett KL. Benzo(a)pyrene induced glycine N-methyltransferase messenger RNA expression in Fundulus heteroclitus embryos. Marine Environmental Research. 69: S74-6. PMID 19892394 DOI: 10.1016/j.marenvres.2009.10.008  0.44
2009 Kasimsetty SG, Bialonska D, Reddy MK, Thornton C, Willett KL, Ferreira D. Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. Journal of Agricultural and Food Chemistry. 57: 10636-44. PMID 19919114 DOI: 10.1021/jf902716r  0.44
2009 Bright NJ, Thornton C, Carling D. The regulation and function of mammalian AMPK-related kinases. Acta Physiologica (Oxford, England). 196: 15-26. PMID 19245655 DOI: 10.1111/j.1748-1716.2009.01971.x  1
2008 Dong W, Wang L, Thornton C, Scheffler BE, Willett KL. Benzo(a)pyrene decreases brain and ovarian aromatase mRNA expression in Fundulus heteroclitus. Aquatic Toxicology (Amsterdam, Netherlands). 88: 289-300. PMID 18571745 DOI: 10.1016/j.aquatox.2008.05.006  0.44
2008 Thornton C, Sardini A, Carling D. Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression. The Journal of Biological Chemistry. 283: 17116-22. PMID 18436530 DOI: 10.1074/jbc.M708987200  1
2008 Bright NJ, Carling D, Thornton C. Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation. The Journal of Biological Chemistry. 283: 14946-54. PMID 18339622 DOI: 10.1074/jbc.M710381200  1
2008 Zhu S, Li L, Thornton C, Carvalho P, Avery BA, Willett KL. Simultaneous determination of benzo[a]pyrene and eight of its metabolites in Fundulus heteroclitus bile using ultra-performance liquid chromatography with mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 863: 141-9. PMID 18255360 DOI: 10.1016/j.jchromb.2008.01.018  0.44
2008 Jurd R, Thornton C, Wang J, Luong K, Phamluong K, Kharazia V, Gibb SL, Ron D. Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. The Journal of Biological Chemistry. 283: 301-10. PMID 17962190 DOI: 10.1074/jbc.M705580200  1
2004 Rastan S, Hough T, Kierman A, Hardisty R, Erven A, Gray IC, Voeling S, Isaacs A, Tsai H, Strivens M, Washbourne R, Thornton C, Greenaway S, Hewitt M, McCormick S, et al. Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders. Genetica. 122: 47-9. PMID 15619960 DOI: 10.1007/s10709-004-1930-x  1
2004 Thornton C, Tang KC, Phamluong K, Luong K, Vagts A, Nikanjam D, Yaka R, Ron D. Spatial and temporal regulation of RACK1 function and N-methyl-D-aspartate receptor activity through WD40 motif-mediated dimerization. The Journal of Biological Chemistry. 279: 31357-64. PMID 15140893 DOI: 10.1074/jbc.M402316200  1
2004 Bartels MJ, Hansen SC, Thornton CM, Brzak KA, Mendrala AL, Dietz FK, Kastl PJ. Pharmacokinetics and metabolism of 14C-1,3-dichloropropene in the Fischer 344 rat and the B6C3F1 mouse. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 193-213. PMID 14985147 DOI: 10.1080/00498250310001636859  0.44
2004 Domoradzki JY, Thornton CM, Pottenger LH, Hansen SC, Card TL, Markham DA, Dryzga MD, Shiotsuka RN, Waechter JM. Age and dose dependency of the pharmacokinetics and metabolism of bisphenol A in neonatal sprague-dawley rats following oral administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. 77: 230-42. PMID 14691203 DOI: 10.1093/toxsci/kfh054  0.44
2003 Domoradzki JY, Pottenger LH, Thornton CM, Hansen SC, Card TL, Markham DA, Dryzga MD, Shiotsuka RN, Waechter JM. Metabolism and pharmacokinetics of bisphenol A (BPA) and the embryo-fetal distribution of BPA and BPA-monoglucuronide in CD Sprague-Dawley rats at three gestational stages. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 21-34. PMID 12915710 DOI: 10.1093/toxsci/kfg206  0.44
2003 Domoradzki JY, Brzak KA, Thornton CM. Hydrolysis kinetics of propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro. Toxicological Sciences : An Official Journal of the Society of Toxicology. 75: 31-9. PMID 12857936 DOI: 10.1093/toxsci/kfg177  0.44
2003 Thornton C, Yaka R, Dinh S, Ron D. H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity. The Journal of Biological Chemistry. 278: 23823-9. PMID 12695509 DOI: 10.1074/jbc.M302389200  1
2002 Yaka R, Thornton C, Vagts AJ, Phamluong K, Bonci A, Ron D. NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1. Proceedings of the National Academy of Sciences of the United States of America. 99: 5710-5. PMID 11943848 DOI: 10.1073/pnas.062046299  1
2000 Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, ... ... Thornton C, et al. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nature Genetics. 25: 440-3. PMID 10932191 DOI: 10.1038/78140  1
2000 Glenister PH, Thornton CE. Cryoconservation - Archiving for the future Mammalian Genome. 11: 565-571. PMID 10886024 DOI: 10.1007/s003350010108  1
2000 Nolan PM, Peters J, Vizor L, Strivens M, Washbourne R, Hough T, Wells C, Glenister P, Thornton C, Martin J, Fisher E, Rogers D, Hagan J, Reavill C, Gray I, et al. Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 500-6. PMID 10886012 DOI: 10.1007/s003350010096  1
1999 Thornton CE, Brown SDM, Glenister PH. Large numbers of mice established by in vitro fertilization with cryopreserved spermatozoa: Implications and applications for genetic resource banks, mutagenesis screens, and mouse backcrosses Mammalian Genome. 10: 987-992. PMID 10501968 DOI: 10.1007/s003359901145  1
1998 Thornton C, Snowden MA, Carling D. Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle. The Journal of Biological Chemistry. 273: 12443-50. PMID 9575201 DOI: 10.1074/jbc.273.20.12443  1
1997 Thornton C, Snowden MA, Carling D. Identification of a novel AMPK beta subunit that is highly expressed in skeletal muscle. Biochemical Society Transactions. 25: S667. PMID 9450095  1
1997 Carling D, Woods A, Thornton C, Cheung PC, Smith FC, Ponticos M, Stein SC. Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism. Biochemical Society Transactions. 25: 1224-8. PMID 9449980  1
1997 Thornton C, Snowden MA, Carling D. 139 identification of a novel ampkβ subunit that is highly expressed in skeletal muscle Biochemical Society Transactions. 25: S668.  1
1995 Laval SH, Glenister PH, Rasberry C, Thornton CE, Mahadevaiah SK, Cooke HJ, Burgoyne PS, Cattanach BM. Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal Proceedings of the National Academy of Sciences of the United States of America. 92: 10403-10407. PMID 7479793 DOI: 10.1073/pnas.92.22.10403  1
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