David T. Curiel - Publications

Affiliations: 
Medicine University of Alabama, Birmingham, Birmingham, AL, United States 

376 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, ... ... Curiel DT, et al. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. PMID 32931734 DOI: 10.1016/j.cell.2020.08.026  0.52
2020 Boucher P, Cui X, Curiel DT. Adenoviral vectors for in vivo delivery of CRISPR-Cas gene editors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32891680 DOI: 10.1016/j.jconrel.2020.09.003  0.32
2020 Lu ZH, Dmitriev IP, Brough DE, Kashentseva EA, Li J, Curiel DT. A new gorilla adenoviral vector with natural lung tropism avoids liver toxicity and is amenable for capsid engineering and vector retargeting. Journal of Virology. PMID 32102889 DOI: 10.1128/JVI.00265-20  0.4
2020 Lee M, Lu ZH, Li J, Kashentseva EA, Dmitriev IP, Mendonca SA, Curiel DT. Targeting tumor neoangiogenesis via targeted adenoviral vector to achieve effective cancer gene therapy for disseminated neoplastic disease. Molecular Cancer Therapeutics. PMID 31907220 DOI: 10.1158/1535-7163.MCT-19-0768  0.4
2019 Broeckel RM, Haese N, Ando T, Dmitriev I, Kreklywich CN, Powers J, Denton M, Smith P, Morrison TE, Heise M, DeFilippis V, Messaoudi I, Curiel DT, Streblow DN. Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease. Frontiers in Immunology. 10: 2563. PMID 31736977 DOI: 10.3389/fimmu.2019.02563  0.52
2019 Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS. A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy. Cell Reports. 28: 2634-2646.e4. PMID 31484074 DOI: 10.1016/j.celrep.2019.08.005  0.32
2019 Stephens CJ, Lauron EJ, Kashentseva E, Lu ZH, Yokoyama WM, Curiel DT. Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30771412 DOI: 10.1016/j.jconrel.2019.02.009  0.52
2019 González-Pastor R, Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Lu ZH, Goedegebuure SP, Podhajcer OL, Curiel DT. Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents. Journal of Ovarian Research. 12: 18. PMID 30767772 DOI: 10.1186/s13048-019-0493-5  0.32
2018 Chondronasiou D, Eisden TTHD, Stam AGM, Matthews QL, Icyuz M, Hooijberg E, Dmitriev I, Curiel DT, de Gruijl TD, van de Ven R. Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs. Vaccines. 6. PMID 30022005 DOI: 10.3390/vaccines6030042  0.6
2018 Fonseca JA, McCaffery JN, Caceres J, Kashentseva E, Singh B, Dmitriev IP, Curiel DT, Moreno A. Inclusion of the murine IgGκ signal peptide increases the cellular immunogenicity of a simian adenoviral vectored Plasmodium vivax multistage vaccine. Vaccine. PMID 29657070 DOI: 10.1016/j.vaccine.2018.03.091  0.52
2018 Stephens CJ, Kashentseva E, Everett W, Kaliberova L, Curiel DT. Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9. Gene Therapy. PMID 29588497 DOI: 10.1038/s41434-018-0003-1  0.52
2017 Kuroki LM, Jin X, Dmitriev IP, Kashentseva EA, Powell MA, Mutch DG, Dietz AB, Curiel DT, Hawkins WG, Spitzer D. Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer. Plos One. 12: e0190125. PMID 29267342 DOI: 10.1371/journal.pone.0190125  0.32
2017 Sharma PK, Dmitriev IP, Kashentseva EA, Raes G, Li L, Kim SW, Lu ZH, Arbeit JM, Fleming TP, Kaliberov SA, Goedegebuure SP, Curiel DT, Gillanders WE. Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Therapy. PMID 29242639 DOI: 10.1038/s41417-017-0002-1  0.32
2017 Fonseca JA, McCaffery JN, Kashentseva E, Singh B, Dmitriev IP, Curiel DT, Moreno A. A prime-boost immunization regimen based on a simian adenovirus 36 vectored multi-stage malaria vaccine induces protective immunity in mice. Vaccine. PMID 28483199 DOI: 10.1016/j.vaccine.2017.04.062  0.52
2017 Naoum GE, Zhu ZB, Buchsbaum DJ, Curiel DT, Arafat WO. Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs. Clinical and Translational Medicine. 6: 11. PMID 28251571 DOI: 10.1186/s40169-017-0140-y  0.32
2016 Bhatia S, O'Bryan SM, Rivera AA, Curiel DT, Mathis JM. CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter. Oncolytic Virotherapy. 5: 99-113. PMID 27957479 DOI: 10.2147/OV.S112107  0.4
2016 Cabrera-Mora M, Fonseca JA, Singh B, Zhao C, Makarova N, Dmitriev I, Curiel DT, Blackwell J, Moreno A. A Recombinant Chimeric Ad5/3 Vector Expressing a Multistage Plasmodium Antigen Induces Protective Immunity in Mice Using Heterologous Prime-Boost Immunization Regimens. Journal of Immunology (Baltimore, Md. : 1950). PMID 27574299 DOI: 10.4049/jimmunol.1501926  0.52
2016 Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, et al. A One Health overview, facilitating advances in comparative medicine and translational research. Clinical and Translational Medicine. 5: 26. PMID 27558513 DOI: 10.1186/s40169-016-0107-4  0.52
2016 Schmidt DJ, Beamer G, Tremblay JM, Steele JA, Kim HB, Wang Y, Debatis M, Sun X, Kashentseva EA, Dmitriev IP, Curiel DT, Shoemaker CB, Tzipori S. A Tetraspecific VHH-based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection. Clinical and Vaccine Immunology : Cvi. PMID 27413067 DOI: 10.1128/CVI.00730-15  0.4
2016 Wambach JA, Yang P, Wegner DJ, Heins HB, Kaliberova LN, Kaliberov SA, Curiel DT, White FV, Hamvas A, Hackett BP, Cole FS. Functional Characterization of ABCA3 Mutations from Infants with Respiratory Distress Syndrome. American Journal of Respiratory Cell and Molecular Biology. PMID 27374344 DOI: 10.1165/rcmb.2016-0008OC  0.4
2016 Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Curiel DT. Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer. Journal of Ovarian Research. 9: 38. PMID 27349517 DOI: 10.1186/s13048-016-0248-5  0.32
2016 Tatzel K, Kuroki L, Dmitriev I, Kashentseva E, Curiel DT, Goedegebuure SP, Powell MA, Mutch DG, Hawkins WG, Spitzer D. Erratum: Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology. Scientific Reports. 6: 25217. PMID 27142169 DOI: 10.1038/srep25217  0.52
2016 Fonseca JA, Cabrera-Mora M, Kashentseva EA, Villegas JP, Fernandez A, Van Pelt A, Dmitriev IP, Curiel DT, Moreno A. A Plasmodium Promiscuous T Cell Epitope Delivered within the Ad5 Hexon Protein Enhances the Protective Efficacy of a Protein Based Malaria Vaccine. Plos One. 11: e0154819. PMID 27128437 DOI: 10.1371/journal.pone.0154819  0.32
2016 Tatzel K, Kuroki L, Dmitriev I, Kashentseva E, Curiel DT, Goedegebuure SP, Powell MA, Mutch DG, Hawkins WG, Spitzer D. Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology. Scientific Reports. 6: 22661. PMID 26935795 DOI: 10.1038/srep22661  0.52
2016 Buggio M, Towe C, Annan A, Kaliberov S, Lu ZH, Stephens C, Arbeit JM, Curiel DT. Pulmonary Vasculature Directed Adenovirus Increases Epithelial Lining Fluid Alpha-1 Antitrypsin Levels. The Journal of Gene Medicine. PMID 26825735 DOI: 10.1002/jgm.2874  0.6
2016 Moayeri M, Tremblay JM, Debatis M, Dmietriev IP, Kashentseva EA, Yeh AJ, Cheung GY, Curiel DT, Leppla S, Shoemaker CB. Adenoviral expression of a bispecific VHH-based neutralizing agent targeting protective antigen provides prophylactic protection from anthrax in mice. Clinical and Vaccine Immunology : Cvi. PMID 26740390 DOI: 10.1128/CVI.00611-15  0.32
2015 Dobbins GC, Ugai H, Curiel DT, Gillespie GY. A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. Plos One. 10: e0145272. PMID 26689910 DOI: 10.1371/journal.pone.0145272  0.6
2015 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 22: 222. PMID 25904493 DOI: 10.1038/cgt.2015.13  0.6
2015 Ghisays F, Brace CS, Yackly SM, Kwon HJ, Mills KF, Kashentseva E, Dmitriev IP, Curiel DT, Imai SI, Ellenberger T. The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs. Cell Reports. PMID 25772354 DOI: 10.1016/j.celrep.2015.02.036  0.6
2015 Weber HL, Gidekel M, Werbajh S, Salvatierra E, Rotondaro C, Sganga L, Haab GA, Curiel DT, Cafferata EG, Podhajcer OL. A Novel CDC25B Promoter-Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1665-74. PMID 25573380 DOI: 10.1158/1078-0432.CCR-14-2316  0.6
2015 Sheoran AS, Dmitriev IP, Kashentseva EA, Cohen O, Mukherjee J, Debatis M, Shearer J, Tremblay JM, Beamer G, Curiel DT, Shoemaker CB, Tzipori S. Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication. Infection and Immunity. 83: 286-91. PMID 25368111 DOI: 10.1128/IAI.02360-14  0.6
2015 Everett WH, Curiel DT. Gene therapy for radioprotection Cancer Gene Therapy. 22: 172-180. DOI: 10.1038/cgt.2015.8  0.6
2014 Liu L, Rogers BE, Aladyshkina N, Cheng B, Lokitz SJ, Curiel DT, Mathis JM. Construction and Radiolabeling of Adenovirus Variants that Incorporate Human Metallothionein into Protein IX for Analysis of Biodistribution. Molecular Imaging. 13: 7290201400022. PMID 28650294 DOI: 10.2310/7290.2014.00022  0.4
2014 Dmitriev IP, Kashentseva EA, Kim KH, Matthews QL, Krieger SS, Parry JJ, Nguyen KN, Akers WJ, Achilefu S, Rogers BE, Alvarez RD, Curiel DT. Monitoring of Biodistribution and Persistence of Conditionally Replicative Adenovirus in a Murine Model of Ovarian Cancer Using Capsid-Incorporated mCherry and Expression of Human Somatostatin Receptor Subtype 2 Gene. Molecular Imaging. 13: 7290201400024. PMID 28650284 DOI: 10.2310/7290.2014.00024  0.6
2014 Dmitriev IP, Kashentseva EA, Kim KH, Matthews QL, Krieger SS, Parry JJ, Nguyen KN, Akers WJ, Achilefu S, Rogers BE, Alvarez RD, Curiel DT. Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene. Molecular Imaging. 13. PMID 25249483 DOI: 10.2310/7290.2014.00024  0.6
2014 Kawamura YI, Adachi Y, Curiel DT, Kawashima R, Kannagi R, Nishimoto N, Dohi T. Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer. Cancer Gene Therapy. 21: 427-33. PMID 25213663 DOI: 10.1038/cgt.2014.46  0.6
2014 Lewis TB, Glasgow JN, Harms AS, Standaert DG, Curiel DT. Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses. 6: 3293-310. PMID 25196484 DOI: 10.3390/v6083293  0.6
2014 Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB. Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein. Plos One. 9: e106422. PMID 25170904 DOI: 10.1371/journal.pone.0106422  0.52
2014 Alqahtani A, Heesom K, Bramson JL, Curiel D, Ugai H, Matthews DA. Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics. The Journal of General Virology. 95: 2504-11. PMID 25096814 DOI: 10.1099/vir.0.068221-0  0.6
2014 Liu L, Rogers BE, Aladyshkina N, Cheng B, Lokitz SJ, Curiel DT, Mathis JM. Construction and radiolabeling of adenovirus variants that incorporate human metallothionein into protein IX for analysis of biodistribution. Molecular Imaging. 13. PMID 25060486 DOI: DOI 10.2310/7290.2014.00022  0.6
2014 Lu ZH, Kaliberov S, Zhang J, Muz B, Azab AK, Sohn RE, Kaliberova L, Du Y, Curiel DT, Arbeit JM. The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 881-92. PMID 24955893 DOI: 10.1038/labinvest.2014.78  0.6
2014 Kaliberov SA, Kaliberova LN, Buggio M, Tremblay JM, Shoemaker CB, Curiel DT. Adenoviral targeting using genetically incorporated camelid single variable domains. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 893-905. PMID 24933423 DOI: 10.1038/labinvest.2014.82  0.6
2014 Sandey M, Bird RC, Das SK, Sarkar D, Curiel DT, Fisher PB, Smith BF. Characterization of the canine mda-7 gene, transcripts and expression patterns. Gene. 547: 23-33. PMID 24865935 DOI: 10.1016/j.gene.2014.05.054  0.6
2014 Uchino J, Curiel DT, Ugai H. Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes. Plos One. 9: e87342. PMID 24503714 DOI: 10.1371/journal.pone.0087342  0.6
2014 Azab BM, Dash R, Das SK, Bhutia SK, Sarkar S, Shen XN, Quinn BA, Dent P, Dmitriev IP, Wang XY, Curiel DT, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV). Journal of Cellular Physiology. 229: 34-43. PMID 23868767 DOI: 10.1002/jcp.24408  0.6
2014 Kaliberov SA, Kaliberova LN, Buchsbaum DJ, Curiel DT. Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus Cancer Gene Therapy. 21: 264-274. DOI: 10.1038/cgt.2014.26  0.6
2013 Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Insulin-like Growth Factor-binding Protein-7 (IGFBP7); A Promising Gene Therapeutic for Hepatocellular Carcinoma (HCC). Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 758-766. PMID 28153326 DOI: 10.1038/mt.2012.282  0.52
2013 Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Curiel DT, Arbeit JM. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice. Plos One. 8: e83933. PMID 24376772 DOI: 10.1371/journal.pone.0083933  0.6
2013 Kaliberov SA, Kaliberova LN, Hong Lu Z, Preuss MA, Barnes JA, Stockard CR, Grizzle WE, Arbeit JM, Curiel DT. Retargeting of gene expression using endothelium specific hexon modified adenoviral vector. Virology. 447: 312-25. PMID 24210128 DOI: 10.1016/j.virol.2013.09.020  0.6
2013 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 20: 445-52. PMID 23928733 DOI: 10.1038/cgt.2013.39  0.6
2013 Nair S, Saed GM, Atta HM, Rajaratnam V, Diamond MP, Curiel DT, Al-Hendy A. Towards gene therapy of postoperative adhesions: fiber and transcriptional modifications enhance adenovirus targeting towards human adhesion cells. Gynecologic and Obstetric Investigation. 76: 119-24. PMID 23920223 DOI: 10.1159/000353426  0.6
2013 Nair S, Curiel DT, Rajaratnam V, Thota C, Al-Hendy A. Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas Human Reproduction. 28: 2398-2406. PMID 23820419 DOI: 10.1093/humrep/det275  0.6
2013 Kim KH, Dmitriev IP, Saddekni S, Kashentseva EA, Harris RD, Aurigemma R, Bae S, Singh KP, Siegal GP, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer. Gynecologic Oncology. 130: 518-24. PMID 23756180 DOI: 10.1016/j.ygyno.2013.06.003  0.6
2013 Viale DL, Cafferata EG, Gould D, Rotondaro C, Chernajovsky Y, Curiel DT, Podhajcer OL, Lopez MV. Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironment. The Journal of Investigative Dermatology. 133: 2576-84. PMID 23604101 DOI: 10.1038/jid.2013.191  0.6
2013 Kim JW, Glasgow JN, Nakayama M, Ak F, Ugai H, Curiel DT. An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer. Plos One. 8: e55533. PMID 23383334 DOI: 10.1371/journal.pone.0055533  0.6
2013 Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC). Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 758-66. PMID 23319057 DOI: 10.1038/mt.2012.282  0.6
2013 Alberti MO, Deshane JS, Chaplin DD, Pereboeva L, Curiel DT, Roth JC. A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism. Gene Therapy. 20: 733-41. PMID 23171918 DOI: 10.1038/gt.2012.91  0.6
2013 Oosterhoff D, Curiel DT, De Gruijl TD. Antigen targeting to dendritic cells for cancer immunotherapy Cancer Immunotherapy: Paradigms, Practice and Promise. 2147483647: 147-171. DOI: 10.1007/978-1-4614-4732-0_6  0.6
2013 Mahalingam D, Brumlik MJ, Waehler R, Curiel DT, Curiel TJ. Targeted toxins in cancer immunotherapy Cancer Immunotherapy: Paradigms, Practice and Promise. 2147483647: 377-396. DOI: 10.1007/978-1-4614-4732-0_12  0.6
2013 Martínez-Flores F, Barrera-López A, Sandoval-Zamora HE, García-Cavazos R, Franco-Bourland RE, Madinaveitia-V JA, Zentella-Dehesa A, Curiel DT, Sakamoto K. Activity of Egr-1 promoter induced by UV light in human primary dermal fibroblasts transduced with Ad-Egr-1/Luc is repressed by betamethasone Gene Therapy and Molecular Biology. 15: 92-106.  0.6
2012 Flatt JW, Fox TL, Makarova N, Blackwell JL, Dmitriev IP, Kashentseva EA, Curiel DT, Stewart PL. CryoEM visualization of an adenovirus capsid-incorporated HIV antigen. Plos One. 7: e49607. PMID 23166728 DOI: 10.1371/journal.pone.0049607  0.6
2012 Williams BJ, Bhatia S, Adams LK, Boling S, Carroll JL, Li XL, Rogers DL, Korokhov N, Kovesdi I, Pereboev AV, Curiel DT, Mathis JM. Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector. Plos One. 7: e46981. PMID 23056548 DOI: 10.1371/journal.pone.0046981  0.6
2012 Beatty MS, Curiel DT. Chapter two--Adenovirus strategies for tissue-specific targeting. Advances in Cancer Research. 115: 39-67. PMID 23021241 DOI: 10.1016/B978-0-12-398342-8.00002-1  0.6
2012 Lopez MV, Rivera AA, Viale DL, Benedetti L, Cuneo N, Kimball KJ, Wang M, Douglas JT, Zhu ZB, Bravo AI, Gidekel M, Alvarez RD, Curiel DT, Podhajcer OL. A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2222-33. PMID 22948673 DOI: 10.1038/mt.2012.147  0.6
2012 Chu QD, Sun G, Pope M, Luraguiz N, Curiel DT, Kim R, Li BD, Mathis JM. Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model. Surgery. 152: 441-8. PMID 22853858 DOI: 10.1016/j.surg.2012.05.040  0.6
2012 Ugai H, Dobbins GC, Wang M, Le LP, Matthews DA, Curiel DT. Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1. Virology. 432: 283-95. PMID 22717133 DOI: 10.1016/j.virol.2012.05.028  0.6
2012 Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. Plos One. 7: e37812. PMID 22624065 DOI: 10.1371/journal.pone.0037812  0.6
2012 Kim KH, Dmitriev I, O'Malley JP, Wang M, Saddekni S, You Z, Preuss MA, Harris RD, Aurigemma R, Siegal GP, Zinn KR, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3440-51. PMID 22510347 DOI: 10.1158/1078-0432.CCR-11-2852  0.6
2012 Hangalapura BN, Timares L, Oosterhoff D, Scheper RJ, Curiel DT, de Gruijl TD. CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic. The Journal of Gene Medicine. 14: 416-27. PMID 22228547 DOI: 10.1002/jgm.1648  0.44
2012 Azab B, Dash R, Das SK, Bhutia SK, Shen XN, Quinn BA, Sarkar S, Wang XY, Hedvat M, Dmitriev IP, Curiel DT, Grant S, Dent P, Reed JC, Pellecchia M, et al. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. Journal of Cellular Physiology. 227: 2145-53. PMID 21780116 DOI: 10.1002/jcp.22947  0.6
2012 Bhutia SK, Das SK, Kegelman TP, Azab B, Dash R, Su ZZ, Wang XY, Rizzi F, Bettuzzi S, Lee SG, Dent P, Grant S, Curiel DT, Sarkar D, Fisher PB. mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer. Journal of Cellular Physiology. 227: 1805-13. PMID 21732348 DOI: 10.1002/jcp.22904  0.6
2011 Quinn BA, Dash R, Azab B, Sarkar S, Das SK, Kumar S, Oyesanya RA, Dasgupta S, Dent P, Grant S, Rahmani M, Curiel DT, Dmitriev I, Hedvat M, Wei J, et al. Targeting Mcl-1 for the therapy of cancer. Expert Opinion On Investigational Drugs. 20: 1397-411. PMID 21851287 DOI: 10.1517/13543784.2011.609167  0.6
2011 Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine. Cancer Research. 71: 5827-37. PMID 21747119 DOI: 10.1158/0008-5472.CAN-11-0804  0.6
2011 Rein DT, Volkmer A, Beyer IM, Curiel DT, Janni W, Dragoi A, Hess AP, Maass N, Baldus SE, Bauerschmitz G, Breidenbach M. Treatment of chemotherapy resistant ovarian cancer with a MDR1 targeted oncolytic adenovirus. Gynecologic Oncology. 123: 138-46. PMID 21741695 DOI: 10.1016/j.ygyno.2011.06.007  0.6
2011 Dent P, Curiel DT, Fisher PB. The potential of virus-based gene therapies for treatment of metastatic kidney cancer. Expert Review of Anticancer Therapy. 11: 809-11. PMID 21707273 DOI: 10.1586/era.11.59  0.6
2011 Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, Lee SG, Dent P, Curiel DT, Sarkar D, Fisher PB. Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24). Autophagy. 7: 1076-7. PMID 21610321 DOI: 10.4161/auto.7.9.16163  0.6
2011 Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, et al. Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8785-90. PMID 21555592 DOI: 10.1073/pnas.1100769108  0.6
2011 Mathis JM, Bhatia S, Khandelwal A, Kovesdi I, Lokitz SJ, Odaka Y, Takalkar AM, Terry T, Curiel DT. Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging. Plos One. 6: e16792. PMID 21347423 DOI: 10.1371/journal.pone.0016792  0.6
2011 O'Neill AM, Smith AN, Spangler EA, Whitley EM, Schleis SE, Bird RC, Curiel DT, Thacker EE, Smith BF. Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins. Cancer Biology & Therapy. 11: 651-8. PMID 21321486 DOI: 10.4161/cbt.11.7.14690  0.6
2011 Dash R, Azab B, Shen XN, Sokhi UK, Sarkar S, Su ZZ, Wang XY, Claudio PP, Dent P, Dmitriev IP, Curiel DT, Grant S, Sarkar D, Fisher PB. Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Discovery Medicine. 11: 46-56. PMID 21276410  0.6
2011 Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine. Vaccine. 29: 2313-21. PMID 21272606 DOI: 10.1016/j.vaccine.2011.01.022  0.6
2011 Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients. Human Gene Therapy. 22: 821-8. PMID 21171861 DOI: 10.1089/hum.2010.180  0.6
2011 Park MA, Hamed HA, Mitchell C, Cruickshanks N, Dash R, Allegood J, Dmitriev IP, Tye G, Ogretmen B, Spiegel S, Yacoub A, Grant S, Curiel DT, Fisher PB, Dent P. A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. Molecular Pharmacology. 79: 368-80. PMID 21119025 DOI: 10.1124/mol.110.069484  0.6
2010 Kimball KJ, Preuss MA, Barnes MN, Wang M, Siegal GP, Wan W, Kuo H, Saddekni S, Stockard CR, Grizzle WE, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5277-87. PMID 20978148 DOI: 10.1158/1078-0432.CCR-10-0791  0.6
2010 Eulitt PJ, Park MA, Hossein H, Cruikshanks N, Yang C, Dmitriev IP, Yacoub A, Curiel DT, Fisher PB, Dent P. Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery. Cancer Biology & Therapy. 10: 1290-305. PMID 20948318 DOI: 10.4161/cbt.10.12.13497  0.6
2010 Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, ... ... Curiel DT, et al. mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine & Growth Factor Reviews. 21: 381-91. PMID 20926331 DOI: 10.1016/j.cytogfr.2010.08.004  0.6
2010 Lewis TB, Glasgow JN, Glandon AM, Curiel DT, Standaert DG. Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy. Plos One. 5. PMID 20862245 DOI: 10.1371/journal.pone.0012672  0.6
2010 Rahmani M, Mayo M, Dash R, Sokhi UK, Dmitriev IP, Sarkar D, Dent P, Curiel DT, Fisher PB, Grant S. Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress. Molecular Pharmacology. 78: 1096-104. PMID 20858700 DOI: 10.1124/mol.110.068007  0.6
2010 Murakami M, Ugai H, Wang M, Belousova N, Dent P, Fisher PB, Glasgow JN, Everts M, Curiel DT. An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations. Virology. 407: 196-205. PMID 20828776 DOI: 10.1016/j.virol.2010.08.010  0.6
2010 Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Molecular Cancer Therapeutics. 9: 2536-44. PMID 20736345 DOI: 10.1158/1535-7163.MCT-10-0332  0.6
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, ... ... Curiel DT, et al. The development of MDA-7/IL-24 as a cancer therapeutic. Pharmacology & Therapeutics. 128: 375-84. PMID 20732354 DOI: 10.1016/j.pharmthera.2010.08.001  0.6
2010 Pennington K, Chu QD, Curiel DT, Li BD, Mathis JM. The utility of a tissue slice model system to determine breast cancer infectivity by oncolytic adenoviruses. The Journal of Surgical Research. 163: 270-5. PMID 20691986 DOI: 10.1016/j.jss.2010.03.072  0.6
2010 Guardado-Calvo P, Muñoz EM, Llamas-Saiz AL, Fox GC, Kahn R, Curiel DT, Glasgow JN, van Raaij MJ. Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains. Journal of Virology. 84: 10558-68. PMID 20686025 DOI: 10.1128/JVI.00997-10  0.6
2010 Matthews QL, Fatima A, Tang Y, Perry BA, Tsuruta Y, Komarova S, Timares L, Zhao C, Makarova N, Borovjagin AV, Stewart PL, Wu H, Blackwell JL, Curiel DT. HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach. Plos One. 5: e11815. PMID 20676400 DOI: 10.1371/journal.pone.0011815  0.6
2010 Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, van den Tol MP, Hooijberg E, Pereboev A, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 706-15. PMID 20664356 DOI: 10.1097/CJI.0b013e3181eccbd4  0.36
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, ... ... Curiel DT, et al. MDA-7/IL-24 as a cancer therapeutic: from bench to bedside. Anti-Cancer Drugs. 21: 725-31. PMID 20613485 DOI: 10.1097/CAD.0b013e32833cfbe1  0.6
2010 Paupoo AAV, Zhu ZB, Wang M, Rein DT, Starzinski-Powitz A, Curiel DT. A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect Human Reproduction. 25: 2068-2083. PMID 20573677 DOI: 10.1093/humrep/deq137  0.6
2010 Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, Curiel DT, Grant S, Pellecchia M, Reed JC, Sarkar D, et al. Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine. Cancer Research. 70: 5034-45. PMID 20501829 DOI: 10.1158/0008-5472.CAN-10-0563  0.6
2010 Komarova S, Roth J, Alvarez R, Curiel DT, Pereboeva L. Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor. Journal of Ovarian Research. 3: 12. PMID 20500878 DOI: 10.1186/1757-2215-3-12  0.6
2010 Bhutia SK, Dash R, Das SK, Azab B, Su ZZ, Lee SG, Grant S, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24. Cancer Research. 70: 3667-76. PMID 20406981 DOI: 10.1158/0008-5472.CAN-09-3647  0.6
2010 Borovjagin AV, McNally LR, Wang M, Curiel DT, MacDougall MJ, Zinn KR. Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging. Molecular Imaging. 9: 59-75. PMID 20236604 DOI: 10.2310/7290.2010.00003  0.6
2010 Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P. Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1130-42. PMID 20179672 DOI: 10.1038/mt.2010.29  0.6
2010 Dash R, Dmitriev I, Su ZZ, Bhutia SK, Azab B, Vozhilla N, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells Cancer Gene Therapy. 17: 447-456. PMID 20150932 DOI: 10.1038/cgt.2009.91  0.6
2010 Hamed HA, Yacoub A, Park MA, Eulitt P, Sarkar D, Dimitrie IP, Chen CS, Grant S, Curiel DT, Fisher PB, Dent P. OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins. Cancer Biology & Therapy. 9: 526-36. PMID 20107314  0.6
2010 Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, Grant S, Curiel DT, Fisher PB, Dent P. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Research. 70: 1120-9. PMID 20103619 DOI: 10.1158/0008-5472.CAN-09-4043  0.6
2010 Li J, Fatima A, Komarova S, Ugai H, Uprety P, Roth JC, Wang M, Oster RA, Curiel DT, Matthews QL. Evaluation of adenovirus capsid labeling versus transgene expression. Virology Journal. 7: 21. PMID 20102632 DOI: 10.1186/1743-422X-7-21  0.6
2010 Yamamoto M, Curiel DT. Current issues and future directions of oncolytic adenoviruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 243-50. PMID 19935777 DOI: 10.1038/mt.2009.266  0.6
2010 Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells. Molecular Pharmacology. 77: 298-310. PMID 19910452 DOI: 10.1124/mol.109.061820  0.6
2010 Murakami M, Ugai H, Belousova N, Pereboev A, Dent P, Fisher PB, Everts M, Curiel DT. Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells. The Prostate. 70: 362-76. PMID 19902467 DOI: 10.1002/pros.21070  0.6
2010 Davydova J, Gavrikova T, Brown EJ, Luo X, Curiel DT, Vickers SM, Yamamoto M. In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy. Cancer Science. 101: 474-81. PMID 19900190 DOI: 10.1111/j.1349-7006.2009.01407.x  0.6
2010 Greco A, Di Benedetto A, Howard CM, Kelly S, Nande R, Dementieva Y, Miranda M, Brunetti A, Salvatore M, Claudio L, Sarkar D, Dent P, Curiel DT, Fisher PB, Claudio PP. Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 295-306. PMID 19888195 DOI: 10.1038/mt.2009.252  1
2010 Ugai H, Wang M, Le LP, Matthews DA, Yamamoto M, Curiel DT. In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection. Journal of Molecular Biology. 395: 55-78. PMID 19853616 DOI: 10.1016/j.jmb.2009.10.034  0.6
2010 Rein DT, Schmidt T, Bauerschmitz G, Hampl M, Beyer IM, Paupoo AA, Curiel DT, Breidenbach M. Treatment of endometriosis with a VEGF-targeted conditionally replicative adenovirus. Fertility and Sterility. 93: 2687-94. PMID 19524222 DOI: 10.1016/j.fertnstert.2009.04.042  1
2009 Uchino J, Takayama K, Harada A, Kawakami Y, Inoue H, Curiel DT, Nakanishi Y. [hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment]. Fukuoka Igaku Zasshi = Hukuoka Acta Medica. 100: 338-48. PMID 20391937  0.6
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors for transcriptional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5219. PMID 20147171 DOI: 10.1101/pdb.prot5219  1
2009 Kawakami Y, Curiel DT. Construction of fusion proteins for transductional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5218. PMID 20147170 DOI: 10.1101/pdb.prot5218  1
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors with RGD-modified fiber for transductional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5217. PMID 20147169 DOI: 10.1101/pdb.prot5217  1
2009 Tang Y, Wu H, Ugai H, Matthews QL, Curiel DT. Derivation of a triple mosaic adenovirus for cancer gene therapy. Plos One. 4: e8526. PMID 20046872 DOI: 10.1371/journal.pone.0008526  0.6
2009 Glasgow JN, Mikheeva G, Krasnykh V, Curiel DT. A strategy for adenovirus vector targeting with a secreted single chain antibody. Plos One. 4: e8355. PMID 20027223 DOI: 10.1371/journal.pone.0008355  0.6
2009 Dent P, Curiel DT, Grant S, Fisher PB. Minting a new class of polo-like-kinase inhibitors. Cancer Biology & Therapy. 8: 2384-5. PMID 20009506  0.6
2009 van de Ven R, Lindenberg JJ, Oosterhoff D, van den Tol MP, Rosalia RA, Murakami M, Everts M, Scheffer GL, Scheper RJ, de Gruijl TD, Curiel DT. Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 895-906. PMID 19816192 DOI: 10.1097/CJI.0b013e3181b56deb  0.32
2009 Kimball KJ, Rivera AA, Zinn KR, Icyuz M, Saini V, Li J, Zhu ZB, Siegal GP, Douglas JT, Curiel DT, Alvarez RD, Borovjagin AV. Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer. Molecular Imaging. 8: 264-77. PMID 19796604 DOI: 10.2310/7290.2009.00025  1
2009 Thacker EE, Nakayama M, Smith BF, Bird RC, Muminova Z, Strong TV, Timares L, Korokhov N, O'Neill AM, de Gruijl TD, Glasgow JN, Tani K, Curiel DT. A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo. Vaccine. 27: 7116-24. PMID 19786146 DOI: 10.1016/j.vaccine.2009.09.055  1
2009 Nelson AR, Davydova J, Curiel DT, Yamamoto M. Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer. Cancer Science. 100: 2181-7. PMID 19689475 DOI: 10.1111/j.1349-7006.2009.01289.x  0.6
2009 Short JJ, Curiel DT. Oncolytic adenoviruses targeted to cancer stem cells. Molecular Cancer Therapeutics. 8: 2096-102. PMID 19671759 DOI: 10.1158/1535-7163.MCT-09-0367  1
2009 Pérez-Berná AJ, Marabini R, Scheres SH, Menéndez-Conejero R, Dmitriev IP, Curiel DT, Mangel WF, Flint SJ, San Martín C. Structure and uncoating of immature adenovirus. Journal of Molecular Biology. 392: 547-57. PMID 19563809 DOI: 10.1016/j.jmb.2009.06.057  1
2009 Matthews K, Noker PE, Tian B, Grimes SD, Fulton R, Schweikart K, Harris R, Aurigemma R, Wang M, Barnes MN, Siegal GP, Hemminki A, Zinn K, Curiel DT, Alvarez RD. Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4131-7. PMID 19509153 DOI: 10.1158/1078-0432.CCR-08-3354  1
2009 Matthews KS, Alvarez RD, Curiel DT. Advancements in adenoviral based virotherapy for ovarian cancer. Advanced Drug Delivery Reviews. 61: 836-41. PMID 19422865 DOI: 10.1016/j.addr.2009.04.012  1
2009 Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, et al. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Molecular Cancer Therapeutics. 8: 1280-91. PMID 19417161 DOI: 10.1158/1535-7163.MCT-09-0073  1
2009 Dent P, Curiel DT, Fisher PB, Grant S. Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 12: 65-73. PMID 19395305 DOI: 10.1016/j.drup.2009.03.001  1
2009 Kashentseva EA, Douglas JT, Zinn KR, Curiel DT, Dmitriev IP. Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody. Journal of Molecular Biology. 388: 443-61. PMID 19285990 DOI: 10.1016/j.jmb.2009.03.016  1
2009 Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, Fisher PB. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biology & Therapy. 8: 391-400. PMID 19276652  1
2009 Haisma HJ, Boesjes M, Beerens AM, van der Strate BW, Curiel DT, Plüddemann A, Gordon S, Bellu AR. Scavenger receptor A: a new route for adenovirus 5. Molecular Pharmaceutics. 6: 366-74. PMID 19227971 DOI: 10.1021/mp8000974  1
2009 Li HJ, Everts M, Yamamoto M, Curiel DT, Herschman HR. Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors. Cancer Research. 69: 554-64. PMID 19147569 DOI: 10.1158/0008-5472.CAN-08-3209  1
2009 Dent P, Grant S, Fisher PB, Curiel DT. PI3K: A rational target for ovarian cancer therapy? Cancer Biology & Therapy. 8: 27-30. PMID 19127116  1
2009 Stoff A, Rivera AA, Banerjee NS, Moore ST, Numnum TM, Espinosa-de-los-Monteros A, Richter DF, Siegal GP, Chow LT, Feldman D, Vasconez LO, Mathis JM, Stoff-Khalili MA, Curiel DT. Promotion of incisional wound repair by human mesenchymal stem cell transplantation Experimental Dermatology. 18: 362-369. PMID 18803656 DOI: 10.1111/j.1600-0625.2008.00792.x  1
2009 Hedley SJ, Krendelshchikov A, Kim MH, Chen J, Hsu HC, Mountz JD, Curiel DT, Kovesdi I. Assessment of genetic shielding for adenovirus vectors Open Gene Therapy Journal. 2: 1-11. DOI: 10.2174/1875037000902010001  0.6
2008 Preuss MA, Glasgow JN, Everts M, Stoff-Khalili MA, Wu H, Curiel DT. Enhanced Gene Delivery to Human Primary Endothelial Cells Using Tropism-Modified Adenovirus Vectors. The Open Gene Therapy Journal. 1: 7-11. PMID 19834585 DOI: 10.2174/1875037000801010007  0.6
2008 Park MA, Zhang G, Mitchell C, Rahmani M, Hamed H, Hagan MP, Yacoub A, Curiel DT, Fisher PB, Grant S, Dent P. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95. Molecular Cancer Therapeutics. 7: 2633-48. PMID 18790746 DOI: 10.1158/1535-7163.MCT-08-0400  1
2008 San Martín C, Glasgow JN, Borovjagin A, Beatty MS, Kashentseva EA, Curiel DT, Marabini R, Dmitriev IP. Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid. Journal of Molecular Biology. 383: 923-34. PMID 18786542 DOI: 10.1016/j.jmb.2008.08.054  1
2008 Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5385-99. PMID 18765530 DOI: 10.1158/1078-0432.CCR-08-0469  1
2008 Paul CP, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CM, Lamfers ML, Siegal GP, Zhu ZB, Curiel DT. Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biology & Therapy. 7: 786-93. PMID 18756624 DOI: 10.4161/cbt.7.5.5421  1
2008 Matthews QL, Yang P, Wu Q, Belousova N, Rivera AA, Stoff-Khalili MA, Waehler R, Hsu HC, Li Z, Li J, Mountz JD, Wu H, Curiel DT. Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach. Virology Journal. 5: 98. PMID 18718011 DOI: 10.1186/1743-422X-5-98  1
2008 Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB. Searching for a cure: gene therapy for glioblastoma. Cancer Biology & Therapy. 7: 1335-40. PMID 18708757  1
2008 Othman EE, Zhu ZB, Curiel DT, Khatoon N, Salem HT, Khalifa EA, Al-Hendy A. Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. American Journal of Obstetrics and Gynecology. 199: 117.e1-6. PMID 18674655 DOI: 10.1016/j.ajog.2008.01.059  1
2008 van de Ven R, Scheffer GL, Reurs AW, Lindenberg JJ, Oerlemans R, Jansen G, Gillet JP, Glasgow JN, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration. Blood. 112: 2353-9. PMID 18625884 DOI: 10.1182/blood-2008-03-147850  1
2008 Tang Y, Le LP, Matthews QL, Han T, Wu H, Curiel DT. Derivation of a triple mosaic adenovirus based on modification of the minor capsid protein IX. Virology. 377: 391-400. PMID 18570971 DOI: 10.1016/j.virol.2008.04.023  1
2008 Chen J, Wang J, Li J, Wu Q, Chu Lim F, Yang P, Hsu HC, Curiel DT, Mountz JD. Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1500-6. PMID 18545221 DOI: 10.1038/mt.2008.121  1
2008 Sekine S, Kataoka K, Fukuyama Y, Adachi Y, Davydova J, Yamamoto M, Kobayashi R, Fujihashi K, Suzuki H, Curiel DT, Shizukuishi S, McGhee JR, Fujihashi K. A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 8126-34. PMID 18523277  1
2008 Tsuruta Y, Pereboeva L, Breidenbach M, Rein DT, Wang M, Alvarez RD, Siegal GP, Dent P, Fisher PB, Curiel DT. A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3582-8. PMID 18519792 DOI: 10.1158/1078-0432.CCR-07-5053  1
2008 Zhu ZB, Lu B, Park M, Makhija SK, Numnum TM, Kendrick JE, Wang M, Tsuruta Y, Fisher P, Alvarez RD, Zhou F, Siegal GP, Wu H, Curiel DT. Development of an optimized conditionally replicative adenoviral agent for ovarian cancer. International Journal of Oncology. 32: 1179-88. PMID 18497979 DOI: 10.3892/ijo_32_6_1179  1
2008 Wu H, Curiel DT. Fiber-modified adenoviruses for targeted gene therapy. Methods in Molecular Biology (Clifton, N.J.). 434: 113-32. PMID 18470642 DOI: 10.1007/978-1-60327-248-3_8  1
2008 Bird RC, Deinnocentes P, Lenz S, Thacker EE, Curiel DT, Smith BF. An allogeneic hybrid-cell fusion vaccine against canine mammary cancer. Veterinary Immunology and Immunopathology. 123: 289-304. PMID 18423623 DOI: 10.1016/j.vetimm.2008.02.013  1
2008 Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus WC, Ramakrishnan V, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB, Dent P. MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biology & Therapy. 7: 917-33. PMID 18376144 DOI: 10.4161/cbt.7.6.5928  1
2008 Roth JC, Curiel DT, Pereboeva L. Cell vehicle targeting strategies Gene Therapy. 15: 716-729. PMID 18369326 DOI: 10.1038/gt.2008.38  1
2008 Ramírez PJ, Vickers SM, Ono HA, Davydova J, Takayama K, Thompson TC, Curiel DT, Bland KI, Yamamoto M. Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model American Journal of Surgery. 195: 481-490. PMID 18361926 DOI: 10.1016/j.amjsurg.2007.04.014  1
2008 Sarkar D, Su ZZ, Park ES, Vozhilla N, Dent P, Curiel DT, Fisher PB. A cancer terminator virus eradicates both primary and distant human melanomas. Cancer Gene Therapy. 15: 293-302. PMID 18323853 DOI: 10.1038/cgt.2008.14  1
2008 Park MA, Yacoub A, Sarkar D, Emdad L, Rahmani M, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P. PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells. Autophagy. 4: 513-5. PMID 18299661  1
2008 Yacoub A, Gupta P, Park MA, Rhamani M, Hamed H, Hanna D, Zhang G, Sarkar D, Lebedeva IV, Emdad L, Koumenis C, Curiel DT, Grant S, Fisher PB, Dent P. Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling Molecular Cancer Therapeutics. 7: 314-329. PMID 18281516 DOI: 10.1158/1535-7163.MCT-07-2150  1
2008 Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, ... Curiel DT, et al. Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells. Molecular Cancer Therapeutics. 7: 297-313. PMID 18281515 DOI: 10.1158/1535-7163.MCT-07-2166  1
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: Not insurmountable therapeutic problems Cancer Biology and Therapy. 7: 109-112. PMID 18277093  1
2008 Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, Fisher PB. Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva. Journal of Cellular Physiology. 215: 827-36. PMID 18270968 DOI: 10.1002/jcp.21369  1
2008 Park MA, Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P. PERK-dependent regulation of HSP70 expression and the regulation of autophagy. Autophagy. 4: 364-7. PMID 18216498  1
2008 Schoehn G, El Bakkouri ME, Fabry CMS, Billet O, Estrozi LF, Le L, Curiel DT, Kajava AV, Ruigrok RWH, Kremer EJ. Three-dimensional structure of canine adenovirus serotype 2 capsid Journal of Virology. 82: 3192-3203. PMID 18216088 DOI: 10.1128/JVI.02393-07  1
2008 Saini V, Martyshkin DV, Mirov SB, Perez A, Perkins G, Ellisman MH, Towner VD, Wu H, Pereboeva L, Borovjagin A, Curiel DT, Everts M. An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 4: 262-9. PMID 18200644 DOI: 10.1002/smll.200700403  1
2008 Hassan MH, Khatoon N, Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells. Human Reproduction (Oxford, England). 23: 514-24. PMID 18184643 DOI: 10.1093/humrep/dem410  1
2008 Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, et al. OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Molecular Pharmacology. 73: 1168-84. PMID 18182481 DOI: 10.1124/mol.107.042697  1
2008 Uchino J, Takayama K, Harada A, Sone T, Harada T, Curiel DT, Kuroki M, Nakanishi Y. Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan Cancer Gene Therapy. 15: 94-100. PMID 18157147 DOI: 10.1038/sj.cgt.7701100  1
2008 Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ. Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy Expert Opinion On Drug Delivery. 5: 87-103. PMID 18095930 DOI: 10.1517/17425247.5.1.87  1
2008 Numnum TM, Makhija S, Lu B, Wang M, Rivera A, Stoff-Khalili M, Alvarez RD, Zhu ZB, Curiel DT. Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines. Gynecologic Oncology. 108: 34-41. PMID 18061250 DOI: 10.1016/j.ygyno.2007.08.096  1
2008 Huang D, Pereboev AV, Korokhov N, He R, Larocque L, Gravel C, Jaentschke B, Tocchi M, Casley WL, Lemieux M, Curiel DT, Chen W, Li X. Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells. Gene Therapy. 15: 298-308. PMID 18046426 DOI: 10.1038/sj.gt.3303085  1
2008 Schierer S, Hesse A, Müller I, Kämpgen E, Curiel DT, Schuler G, Steinkasserer A, Nettelbeck DM. Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses International Journal of Cancer. 122: 219-229. PMID 17764070 DOI: 10.1002/ijc.23074  1
2008 Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, DeBenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Research and Treatment. 108: 43-55. PMID 17508279 DOI: 10.1007/s10549-007-9587-7  1
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. INGN-241: Cancer gene therapy Drugs of the Future. 33: 396-401. DOI: 10.1358/dof.2008.033.05.1201624  1
2008 Paul CPL, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CMF, Lamfers MLM, Siegal GP, Zhu ZB, Curiel DT. Characterization of infectivity of knob-modified adenoviral vectors in glioma Cancer Biology and Therapy. 7: 788-795.  1
2007 Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P. Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells. Molecular Cancer Therapeutics. 6: 3101-12. PMID 18065490 DOI: 10.1158/1535-7163.MCT-07-0561  1
2007 Emdad L, Lebedeva IV, Su ZZ, Sarkar D, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells. Molecular Cancer Therapeutics. 6: 2985-94. PMID 18025283 DOI: 10.1158/1535-7163.MCT-07-0399  1
2007 Zhu ZB, Mathis JM, Makhija SK, Lu B, Wang M, Ji S, Rivera AA, Rosenthal EL, Siegal GP, Curiel DT. Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck. International Journal of Oncology. 31: 1213-22. PMID 17912450  0.6
2007 Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, ... ... Curiel DT, et al. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). International Journal of Oncology. 31: 985-1007. PMID 17912425  0.6
2007 Ulasov IV, Rivera AA, Han Y, Curiel DT, Zhu ZB, Lesniak MS. Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells Journal of Neurosurgery. 107: 617-627. PMID 17886563 DOI: 10.3171/JNS-07/09/0617  1
2007 Miura Y, Yoshida K, Nishimoto T, Hatanaka K, Ohnami S, Asaka M, Douglas JT, Curiel DT, Yoshida T, Aoki K. Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob. Gene Therapy. 14: 1448-60. PMID 17700705 DOI: 10.1038/sj.gt.3303007  1
2007 Gaballah K, Hills A, Curiel D, Hallden G, Harrison P, Partridge M. Lysis of dysplastic but not normal oral keratinocytes and tissue-engineered epithelia with conditionally replicating adenoviruses Cancer Research. 67: 7284-7294. PMID 17671197 DOI: 10.1158/0008-5472.CAN-06-3834  1
2007 Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS. Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma Human Gene Therapy. 18: 589-602. PMID 17630837 DOI: 10.1089/hum.2007.002  1
2007 Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy Nature Reviews Genetics. 8: 573-587. PMID 17607305 DOI: 10.1038/nrg2141  1
2007 Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P. Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling. Molecular Pharmacology. 72: 704-14. PMID 17578896 DOI: 10.1124/mol.107.038406  1
2007 Sarkar D, Lebedeva IV, Su ZZ, Park ES, Chatman L, Vozhilla N, Dent P, Curiel DT, Fisher PB. Eradication of therapy-resistant human prostate tumors using a cancer terminator virus. Cancer Research. 67: 5434-42. PMID 17545625 DOI: 10.1158/0008-5472.CAN-07-0195  1
2007 Li HJ, Everts M, Pereboeva L, Komarova S, Idan A, Curiel DT, Herschman HR. Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer Research. 67: 5354-61. PMID 17545616 DOI: 10.1158/0008-5472.CAN-06-4679  1
2007 Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS. Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models. Neuro-Oncology. 9: 280-90. PMID 17522331 DOI: 10.1215/15228517-2007-017  1
2007 Sarkar D, Lebedeva IV, Gupta P, Emdad L, Sauane M, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7 (mda-7)/IL-24: A 'magic bullet' for cancer therapy? Expert Opinion On Biological Therapy. 7: 577-586. PMID 17477796 DOI: 10.1517/14712598.7.5.577  1
2007 Tsuruta Y, Pereboeva L, Glasgow JN, Rein DT, Kawakami Y, Alvarez RD, Rocconi RP, Siegal GP, Dent P, Fisher PB, Curiel DT. A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2777-83. PMID 17473211 DOI: 10.1158/1078-0432.CCR-06-2706  1
2007 Page JG, Tian B, Schweikart K, Tomaszewski J, Harris R, Broadt T, Polley-Nelson J, Noker PE, Wang M, Makhija S, Aurigemma R, Curiel DT, Alvarez RD. Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer. American Journal of Obstetrics and Gynecology. 196: 389.e1-9; discussion. PMID 17403430 DOI: 10.1016/j.ajog.2006.12.016  1
2007 Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Radiation-induced cell signaling: inside-out and outside-in. Molecular Cancer Therapeutics. 6: 789-801. PMID 17363476 DOI: 10.1158/1535-7163.MCT-06-0596  1
2007 Lebedeva IV, Washington I, Sarkar D, Clark JA, Fine RL, Dent P, Curiel DT, Turro NJ, Fisher PB. Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 3484-9. PMID 17360670 DOI: 10.1073/pnas.0700042104  1
2007 Yoshio-Hoshino N, Adachi Y, Aoki C, Pereboev A, Curiel DT, Nishimoto N. Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor. Cancer Research. 67: 871-5. PMID 17283116 DOI: 10.1158/0008-5472.CAN-06-3641  1
2007 Reynolds AM, Xia W, Holmes MD, Hodge SJ, Danilov S, Curiel DT, Morrell NW, Reynolds PN. Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1182-92. PMID 17277049 DOI: 10.1152/ajplung.00020.2006  1
2007 Preuss MA, Curiel DT. Gene therapy: science fiction or reality? Southern Medical Journal. 100: 101-4. PMID 17269545 DOI: 10.1097/SMJ.0b013e31802e65dd  1
2007 Matthews QL, Curiel DT. Gene therapy: Human germline genetic modifications - Assessing the scientific, socioethical, and religious issues Southern Medical Journal. 100: 98-100. PMID 17269544 DOI: 10.1097/SMJ.0b013e31802e645f  1
2007 Pereboeva L, Komarova S, Roth J, Ponnazhagan S, Curiel DT. Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus Gene Therapy. 14: 627-637. PMID 17251987 DOI: 10.1038/sj.gt.3302916  1
2007 Lam JT, Hemminki A, Kanerva A, Lee KB, Blackwell JL, Desmond R, Siegal GP, Curiel DT. A three-dimensional assay for measurement of viral-induced oncolysis Cancer Gene Therapy. 14: 421-430. PMID 17235353 DOI: 10.1038/sj.cgt.7701028  1
2007 Perreau M, Mennechet F, Serratrice N, Glasgow JN, Curiel DT, Wodrich H, Kremer EJ. Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. Journal of Virology. 81: 3272-84. PMID 17229706 DOI: 10.1128/JVI.01530-06  1
2007 Stoff-Khalili MA, Rivera AA, Mathis JM, Banerjee NS, Moon AS, Hess A, Rocconi RP, Numnum TM, Everts M, Chow LT, Douglas JT, Siegal GP, Zhu ZB, Bender HG, Dall P, ... ... Curiel DT, et al. Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma. Breast Cancer Research and Treatment. 105: 157-67. PMID 17221158 DOI: 10.1007/s10549-006-9449-8  1
2007 Stoff A, Rivera AA, Mathis JM, Moore ST, Banerjee NS, Everts M, Espinosa-de-los-Monteros A, Novak Z, Vasconez LO, Broker TR, Richter DF, Feldman D, Siegal GP, Stoff-Khalili MA, Curiel DT. Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds. Journal of Molecular Medicine (Berlin, Germany). 85: 481-96. PMID 17219096 DOI: 10.1007/s00109-006-0148-z  1
2007 Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M, Su ZZ, Grant S, Dent P, Curiel DT, Senzer N, Nemunaitis J. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma. Toxicology and Applied Pharmacology. 224: 300-7. PMID 17208263 DOI: 10.1016/j.taap.2006.11.021  1
2007 Ugai H, Borovjagin AV, Le LP, Wang M, Curiel DT. Thermostability/Infectivity Defect Caused by Deletion of the Core Protein V Gene in Human Adenovirus Type 5 Is Rescued by Thermo-selectable Mutations in the Core Protein X Precursor Journal of Molecular Biology. 366: 1142-1160. PMID 17208253 DOI: 10.1016/j.jmb.2006.11.090  1
2007 Witlox MA, Lamfers ML, Wuisman PIJM, Curiel DT, Siegal GP. Evolving gene therapy approaches for osteosarcoma using viral vectors: Review Bone. 40: 797-812. PMID 17189720 DOI: 10.1016/j.bone.2006.10.017  1
2007 Rocconi RP, Zhu ZB, Stoff-Khalili M, Rivera AA, Lu B, Wang M, Alvarez RD, Curiel DT, Makhija SK. Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd) Gynecologic Oncology. 105: 113-121. PMID 17173958 DOI: 10.1016/j.ygyno.2006.10.057  1
2007 Tang Y, Han T, Everts M, Zhu ZB, Gillespie GY, Curiel DT, Wu H. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Therapy. 14: 523-32. PMID 17167498 DOI: 10.1038/sj.gt.3302888  1
2007 Stoff-Khalili MA, Rivera AA, Stoff A, Mathis JM, Rocconi RP, Matthews QL, Numnum MT, Herrmann I, Dall P, Eckhoff DE, Douglas JT, Siegal GP, Zhu ZB, Curiel DT. Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer International Journal of Cancer. 120: 935-941. PMID 17131341 DOI: 10.1002/ijc.22338  1
2007 Zhu ZB, Rivera AA, Makhija SK, Lu B, Wang M, Izumi M, Cerfolio RJ, Stoff-Khalili MA, Zhou F, Takayama K, Siegal GP, Curiel DT. Targeting lung cancer using an infectivity enhanced CXCR4-CRAd Lung Cancer. 55: 145-156. PMID 17113184 DOI: 10.1016/j.lungcan.2006.10.012  1
2007 Yacoub A, Hawkins W, Hanna D, Young H, Park MA, Grant M, Roberts JD, Curiel DT, Fisher PB, Valerie K, Grant S, Hagan MP, Dent P. Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment. Molecular Pharmacology. 71: 259-75. PMID 17050804 DOI: 10.1124/mol.106.031153  1
2007 Takayama K, Reynolds PN, Adachi Y, Kaliberova L, Uchino J, Nakanishi Y, Curiel DT. Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application Cancer Gene Therapy. 14: 105-116. PMID 17024232 DOI: 10.1038/sj.cgt.7700991  1
2007 Jung JS, Stoff A, Rivera AA, Mathis JM, Hess A, Rein D, Fleisch MC, Dall P, Curiel DT, Niederacher D, Bender HG, Stoff-Khalili MA. Stem cells as cellular vehicles for virotherapeutic agents in metastatic breast cancer | Stammzellen als zelluläre vehikel virotherapeutischer agenzien beim metastasierten mammakarzinom Geburtshilfe Und Frauenheilkunde. 67: 236-241. DOI: 10.1055/s-2007-965053  1
2007 Passineau MJ, Curiel DT. Gene transfer and expression in the vascular endothelium Endothelial Biomedicine. 1725-1733. DOI: 10.1017/CBO9780511546198.186  0.6
2007 Matthews QL, Curiel DT. Vector Targeting Concepts in Genetic Medicine. 223-228. DOI: 10.1002/9780470184585.ch18  1
2006 Gommans WM, Oosterhuis D, Dmitriev I, Schaack J, Curiel DT, Haisma HJ, Rots MG. Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill. Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: e64-6. PMID 17718975 DOI: 10.1016/j.jconrel.2006.09.052  1
2006 Smith BF, Curiel DT, Ternovoi VV, Borovjagin AV, Baker HJ, Cox N, Siegal GP. Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs. Cancer Biotherapy & Radiopharmaceuticals. 21: 601-6. PMID 17257075 DOI: 10.1089/cbr.2006.21.601  1
2006 Matthews QL, Sibley DA, Wu H, Li J, Stoff-Khalili MA, Waehler R, Mathis JM, Curiel DT. Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion. Molecular Imaging. 5: 510-9. PMID 17150163 DOI: 10.2310/7290.2006.00029  1
2006 Ambati BK, Nozaki M, Singh N, Takeda A, Jani PD, Suthar T, Albuquerque RJ, Richter E, Sakurai E, Newcomb MT, Kleinman ME, Caldwell RB, Lin Q, Ogura Y, Orecchia A, ... ... Curiel DT, et al. Corneal avascularity is due to soluble VEGF receptor-1. Nature. 443: 993-7. PMID 17051153 DOI: 10.1038/nature05249  1
2006 Stoff A, Rivera AA, Banerjee NS, Mathis JM, Espinosa-de-los-Monteros A, Le LP, De la Torre JI, Vasconez LO, Broker TR, Richter DF, Stoff-Khalili MA, Curiel DT. Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 14: 608-17. PMID 17014674 DOI: 10.1111/j.1743-6109.2006.00168.x  1
2006 Tyler MA, Ulasov IV, Borovjagin A, Sonabend AM, Khramtsov A, Han Y, Dent P, Fisher PB, Curiel DT, Lesniak MS. Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus Molecular Cancer Therapeutics. 5: 2408-2416. PMID 16985075 DOI: 10.1158/1535-7163.MCT-06-0187  1
2006 Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, Aird WC. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. The Journal of Biological Chemistry. 281: 35544-53. PMID 16980307 DOI: 10.1074/jbc.M608620200  1
2006 Short JJ, Vasu C, Holterman MJ, Curiel DT, Pereboev A. Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors. Virus Research. 122: 144-53. PMID 16920215 DOI: 10.1016/j.virusres.2006.07.009  1
2006 Belousova N, Harris R, Zinn K, Rhodes-Selser MA, Kotov A, Kotova O, Wang M, Aurigemma R, Zhu ZB, Curiel DT, Alvarez RD. Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette. Molecular Pharmacology. 70: 1488-93. PMID 16896072 DOI: 10.1124/mol.106.025619  1
2006 Rocconi RP, Numnum MT, Zhu ZB, Lu B, Wang M, Rivera AA, Stoff-Khalili M, Alvarez RD, Curiel DT, Makhija S. Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy Gynecologic Oncology. 103: 985-989. PMID 16857247 DOI: 10.1016/j.ygyno.2006.06.005  1
2006 Chen J, Hsu HC, Zajac AJ, Wu Q, Yang P, Xu X, McPherson SA, Li J, Curiel DT, Mountz JD. In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin. Human Gene Therapy. 17: 669-82. PMID 16776575 DOI: 10.1089/hum.2006.17.669  1
2006 Ternovoi VV, Curiel DT, Smith BF, Siegal GP. Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 748-66. PMID 16751779 DOI: 10.1038/labinvest.3700444  1
2006 Kangasniemi L, Kiviluoto T, Kanerva A, Raki M, Ranki T, Sarkioja M, Wu H, Marini F, Höckerstedt K, Isoniemi H, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3137-44. PMID 16707613 DOI: 10.1158/1078-0432.CCR-05-2576  1
2006 Le LP, Le HN, Nelson AR, Matthews DA, Yamamoto M, Curiel DT. Core labeling of adenovirus with EGFP Virology. 351: 291-302. PMID 16678874 DOI: 10.1016/j.virol.2006.03.042  1
2006 Mathis JM, Stewart PL, Zhu ZB, Curiel DT. Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2651-6. PMID 16675555 DOI: 10.1158/1078-0432.CCR-06-0497  1
2006 Emdad L, Sarkar D, Lebedeva IV, Su ZZ, Gupta P, Mahasreshti PJ, Dent P, Curiel DT, Fisher PB. Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer. Journal of Cellular Physiology. 208: 298-306. PMID 16646087 DOI: 10.1002/jcp.20663  0.32
2006 Adachi Y, Aoki C, Yoshio-Hoshino N, Takayama K, Curiel DT, Nishimoto N. Interleukin-6 induces both cell growth and VEGF production in malignant mesotheliomas. International Journal of Cancer. Journal International Du Cancer. 119: 1303-11. PMID 16642474 DOI: 10.1002/ijc.22006  1
2006 Van Houdt WJ, Haviv YS, Lu B, Wang M, Rivera AA, Ulasov IV, Lamfers MLM, Rein D, Lesniak MS, Siegal GP, Dirven CMF, Curiel DT, Zhu ZB. The human survivin promoter: A novel transcriptional targeting strategy for treatment of glioma Journal of Neurosurgery. 104: 583-592. PMID 16619663 DOI: 10.3171/jns.2006.104.4.583  1
2006 Hedley SJ, Chen J, Mountz JD, Li J, Curiel DT, Korokhov N, Kovesdi I. Targeted and shielded adenovectors for cancer therapy. Cancer Immunology, Immunotherapy : Cii. 55: 1412-9. PMID 16612598 DOI: 10.1007/s00262-006-0158-2  1
2006 Everts M, Saini V, Leddon JL, Kok RJ, Stoff-Khalili M, Preuss MA, Millican CL, Perkins G, Brown JM, Bagaria H, Nikles DE, Johnson DT, Zharov VP, Curiel DT. Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Letters. 6: 587-91. PMID 16608249 DOI: 10.1021/nl0500555  1
2006 Rein DT, Breidenbach M, Hille S, Curiel DT. Current developments in adenovirus-based cancer gene therapy Future Oncology. 2: 137-144. PMID 16556080 DOI: 10.2217/14796694.2.1.137  1
2006 Nakayama M, Both GW, Banizs B, Tsuruta Y, Yamamoto S, Kawakami Y, Douglas JT, Tani K, Curiel DT, Glasgow JN. An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice. Virology. 350: 103-15. PMID 16516257 DOI: 10.1016/j.virol.2006.01.037  1
2006 Glasgow JN, Everts M, Curiel DT. Transductional targeting of adenovirus vectors for gene therapy. Cancer Gene Therapy. 13: 830-44. PMID 16439993 DOI: 10.1038/sj.cgt.7700928  1
2006 Stoff-Khalili MA, Rivera AA, Le LP, Stoff A, Everts M, Contreras JL, Chen D, Teng L, Rots MG, Haisma HJ, Rocconi RP, Bauerschmitz GJ, Rein DT, Yamamoto M, Siegal GP, ... ... Curiel DT, et al. Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents Cancer Gene Therapy. 13: 606-618. PMID 16410819 DOI: 10.1038/sj.cgt.7700934  1
2006 Noureddini SC, Krendelshchikov A, Simonenko V, Hedley SJ, Douglas JT, Curiel DT, Korokhov N. Generation and selection of targeted adenoviruses embodying optimized vector properties. Virus Research. 116: 185-95. PMID 16293334 DOI: 10.1016/j.virusres.2005.10.002  1
2006 Le LP, Rivera AA, Glasgow JN, Ternovoi VV, Wu H, Wang M, Smith BF, Siegal GP, Curiel DT. Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells. Gene Therapy. 13: 389-99. PMID 16292351 DOI: 10.1038/sj.gt.3302674  1
2006 Breidenbach M, Rein DT, Schöndorf T, Khan KN, Herrmann I, Schmidt T, Reynolds PN, Vlodavsky I, Haviv YS, Curiel DT. A new targeting approach for breast cancer gene therapy using the Heparanase promoter Cancer Letters. 240: 114-122. PMID 16271435 DOI: 10.1016/j.canlet.2005.09.007  1
2006 Mahasreshti PJ, Kataram M, Wu H, Yalavarthy LP, Carey D, Fisher PB, Chada S, Alvarez RD, Haisma HJ, Dent P, Curiel DT. Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy. Gynecologic Oncology. 100: 521-32. PMID 16225913 DOI: 10.1016/j.ygyno.2005.08.042  1
2006 Hedley SJ, Auf der Maur A, Hohn S, Escher D, Barberis A, Glasgow JN, Douglas JT, Korokhov N, Curiel DT. An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery. Gene Therapy. 13: 88-94. PMID 16107860 DOI: 10.1038/sj.gt.3302603  1
2006 Gommans WM, van Eert SJ, McLaughlin PM, Harmsen MC, Yamamoto M, Curiel DT, Haisma HJ, Rots MG. The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context. Cancer Gene Therapy. 13: 150-8. PMID 16096650 DOI: 10.1038/sj.cgt.7700882  0.48
2006 Rots MG, Elferink MG, Gommans WM, Oosterhuis D, Schalk JA, Curiel DT, Olinga P, Haisma HJ, Groothuis GM. An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents. The Journal of Gene Medicine. 8: 35-41. PMID 16044485 DOI: 10.1002/jgm.815  0.48
2005 Stoff-Khalili MA, Stoff A, Rivera AA, Banerjee NS, Everts M, Young S, Siegal GP, Richter DF, Wang M, Dall P, Mathis JM, Zhu ZB, Curiel DT. Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system. Breast Cancer Research : Bcr. 7: R1141-52. PMID 16457694 DOI: 10.1186/bcr1353  0.6
2005 Passineau MJ, Siegal GP, Everts M, Pereboev A, Jhala D, Wang M, Zhu ZB, Park SK, Curiel DT, Nelson GM. The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma. Leukemia & Lymphoma. 46: 1627-1638. PMID 16334907 DOI: 10.1080/10428190500221454x  0.36
2005 Mathis JM, Stoff-Khalili MA, Curiel DT. Oncolytic adenoviruses - selective retargeting to tumor cells. Oncogene. 24: 7775-91. PMID 16299537 DOI: 10.1038/sj.onc.1209044  1
2005 Stoff-Khalili MA, Stoff A, Rivera AA, Mathis JM, Everts M, Wang M, Kawakami Y, Waehler R, Mathews QL, Yamamoto M, Rocconi RP, Siegal GP, Richter DF, Dall P, Zhu ZB, ... Curiel DT, et al. Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system. Cancer Biology & Therapy. 4: 1203-10. PMID 16177567 DOI: 10.4161/cbt.4.11.2084  1
2005 Izumi M, Kawakami Y, Glasgow JN, Belousova N, Everts M, Kim-Park S, Yamamoto S, Wang M, Le LP, Reynolds PN, Curiel DT. In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model. The Journal of Gene Medicine. 7: 1517-25. PMID 16170831 DOI: 10.1002/jgm.806  1
2005 Tsuruta Y, Pereboeva L, Glasgow JN, Luongo CL, Komarova S, Kawakami Y, Curiel DT. Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway. Biochemical and Biophysical Research Communications. 335: 205-14. PMID 16061208 DOI: 10.1016/j.bbrc.2005.07.054  0.44
2005 Stoff-Khalili MA, Rivera AA, Glasgow JN, Le LP, Stoff A, Everts M, Tsuruta Y, Kawakami Y, Bauerschmitz GJ, Mathis JM, Pereboeva L, Seigal GP, Dall P, Curiel DT. A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy. Gene Therapy. 12: 1696-706. PMID 16034451 DOI: 10.1038/sj.gt.3302588  1
2005 Li J, Le L, Sibley DA, Mathis JM, Curiel DT. Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion. Virology. 338: 247-58. PMID 15996701 DOI: 10.1016/j.virol.2005.04.005  1
2005 Dent P, Yacoub A, Grant S, Curiel DT, Fisher PB. MDA-7/IL-24 regulates proliferation, invasion and tumor cell radiosensitivity: A new cancer therapy? Journal of Cellular Biochemistry. 95: 712-719. PMID 15880678 DOI: 10.1002/jcb.20502  1
2005 Chen J, Zajac AJ, McPherson SA, Hsu HC, Yang P, Wu Q, Xu X, Wang X, Fujihashi K, Curiel DT, Mountz JD. Primary adenovirus-specific cytotoxic T lymphocyte response occurs after viral clearance and liver enzyme elevation. Gene Therapy. 12: 1079-88. PMID 15815704 DOI: 10.1038/sj.gt.3302494  1
2005 Everts M, Kim-Park SA, Preuss MA, Passineau MJ, Glasgow JN, Pereboev AV, Mahasreshti PJ, Grizzle WE, Reynolds PN, Curiel DT. Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors. Gene Therapy. 12: 1042-8. PMID 15789059 DOI: 10.1038/sj.gt.3302491  1
2005 Korokhov N, de Gruijl TD, Aldrich WA, Triozzi PL, Banerjee PT, Gillies SD, Curiel TJ, Douglas JT, Scheper RJ, Curiel DT. High efficiency transduction of dendritic cells by adenoviral vectors targeted to DC-SIGN. Cancer Biology & Therapy. 4: 289-94. PMID 15753654 DOI: 10.4161/cbt.4.3.1499  1
2005 Wu H, Han T, Belousova N, Krasnykh V, Kashentseva E, Dmitriev I, Kataram M, Mahasreshti PJ, Curiel DT. Identification of sites in adenovirus hexon for foreign peptide incorporation. Journal of Virology. 79: 3382-90. PMID 15731232 DOI: 10.1128/JVI.79.6.3382-3390.2005  1
2005 Borovjagin AV, Krendelchtchikov A, Ramesh N, Yu DC, Douglas JT, Curiel DT. Complex mosaicism is a novel approach to infectivity enhancement of adenovirus type 5-based vectors. Cancer Gene Therapy. 12: 475-86. PMID 15706356 DOI: 10.1038/sj.cgt.7700806  1
2005 Ono HA, Davydova JG, Adachi Y, Takayama K, Barker SD, Reynolds PN, Krasnykh VN, Kunisaki C, Shimada H, Curiel DT, Yamamoto M. Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer. Journal of Gastroenterology. 40: 31-42. PMID 15692787 DOI: 10.1007/s00535-004-1490-y  1
2005 Ternovoi VV, Le LP, Belousova N, Smith BF, Siegal GP, Curiel DT. Productive replication of human adenovirus type 5 in canine cells. Journal of Virology. 79: 1308-11. PMID 15613357 DOI: 10.1128/JVI.79.2.1308-1311.2005  1
2005 Breidenbach M, Rein DT, Everts M, Glasgow JN, Wang M, Passineau MJ, Alvarez RD, Korokhov N, Curiel DT. Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy. Gene Therapy. 12: 187-93. PMID 15526007 DOI: 10.1038/sj.gt.3302404  1
2005 Kanerva A, Zinn KR, Peng KW, Ranki T, Kangasniemi L, Chaudhuri TR, Desmond RA, Wang M, Takayama K, Hakkarainen T, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus. Gene Therapy. 12: 87-94. PMID 15385953 DOI: 10.1038/sj.gt.3302387  1
2005 Mahendra G, Kumar S, Isayeva T, Mahasreshti PJ, Curiel DT, Stockardt CR, Grizzle WE, Alapati V, Singh R, Siegal GP, Meleth S, Ponnazhagan S. Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Therapy. 12: 26-34. PMID 15359287 DOI: 10.1038/sj.cgt.7700754  1
2005 Breidenbach M, Rimbach S, Rath W, Curiel DT, Rein DT. A novel transcriptional targeting strategy for breast cancer gene therapy Geburtshilfe Und Frauenheilkunde. 65: 186-191. DOI: 10.1055/s-2005-837498  1
2004 Kirby TO, Rivera A, Rein D, Wang M, Ulasov I, Breidenbach M, Kataram M, Contreras JL, Krumdieck C, Yamamoto M, Rots MG, Haisma HJ, Alvarez RD, Mahasreshti PJ, Curiel DT. A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8697-703. PMID 15623655 DOI: 10.1158/1078-0432.CCR-04-1166  1
2004 Liang Q, Yamamoto M, Curiel DT, Herschman HR. Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 395-404. PMID 15564150 DOI: 10.1016/j.mibio.2004.09.002  1
2004 Liang Q, Dmitriev I, Kashentseva E, Curiel DT, Herschman HR. Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 385-94. PMID 15564149 DOI: 10.1016/j.mibio.2004.09.001  1
2004 Rein DT, Breidenbach M, Nettelbeck DM, Kawakami Y, Siegal GP, Huh WK, Wang M, Hemminki A, Bauerschmitz GJ, Yamamoto M, Adachi Y, Takayama K, Dall P, Curiel DT. Evaluation of tissue-specific promoters in carcinomas of the cervix uteri Journal of Gene Medicine. 6: 1281-1289. PMID 15368588 DOI: 10.1002/jgm.606  1
2004 Leath CA, Kataram M, Bhagavatula P, Gopalkrishnan RV, Dent P, Fisher PB, Pereboev A, Carey D, Lebedeva IV, Haisma HJ, Alvarez RD, Curiel DT, Mahasreshti PJ. Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinoma. Gynecologic Oncology. 94: 352-62. PMID 15297172 DOI: 10.1016/j.ygyno.2004.04.028  0.48
2004 Rein DT, Breidenbach M, Wu H, Han T, Haviv YS, Wang M, Kirby TO, Kawakami Y, Dall P, Alvarez RD, Curiel DT. Gene transfer to cervical cancer with fiber-modified adenoviruses. International Journal of Cancer. Journal International Du Cancer. 111: 698-704. PMID 15252838 DOI: 10.1002/ijc.20295  1
2004 Contreras JL, Smyth CA, Curiel DT, Eckhoff DE. Nonhuman primate models in type 1 diabetes research. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 45: 334-42. PMID 15229380 DOI: 10.1093/ilar.45.3.334  1
2004 Yacoub A, Mitchell C, Hong Y, Gopalkrishnan RV, Su ZZ, Gupta P, Sauane M, Lebedeva IV, Curiel DT, Mahasreshti PJ, Rosenfeld MR, Broaddus WC, James CD, Grant S, Fisher PB, et al. MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells. Cancer Biology & Therapy. 3: 739-51. PMID 15197348  1
2004 Glasgow JN, Kremer EJ, Hemminki A, Siegal GP, Douglas JT, Curiel DT. An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism. Virology. 324: 103-16. PMID 15183058 DOI: 10.1016/j.virol.2004.03.028  1
2004 Breidenbach M, Rein DT, Wang M, Nettelbeck DM, Hemminki A, Ulasov I, Rivera AR, Everts M, Alvarez RD, Douglas JT, Curiel DT. Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy. Human Gene Therapy. 15: 509-18. PMID 15144580 DOI: 10.1089/10430340460745829  1
2004 Bonner JA, Buchsbaum DJ, Russo SM, Fiveash JB, Trummell HQ, Curiel DT, Raisch KP. Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression. International Journal of Radiation Oncology, Biology, Physics. 59: 2-10. PMID 15142629 DOI: 10.1016/j.ijrobp.2004.01.053  1
2004 Preuss MA, Lam JT, Wang M, Leath CA, Kataram M, Mahasreshti PJ, Alvarez RD, Curiel DT. Transcriptional blocks limit adenoviral replication in primary ovarian tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3189-94. PMID 15131060 DOI: 10.1158/1078-0432.CCR-03-0802  1
2004 Short JJ, Pereboev AV, Kawakami Y, Vasu C, Holterman MJ, Curiel DT. Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors. Virology. 322: 349-59. PMID 15110532 DOI: 10.1016/j.virol.2004.02.016  1
2004 Glasgow JN, Bauerschmitz GJ, Curiel DT, Hemminki A. Transductional and transcriptional targeting of adenovirus for clinical applications. Current Gene Therapy. 4: 1-14. PMID 15032610 DOI: 10.2174/1566523044577997  0.32
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Kaliberova L, Liu B, Rivera AA, Nettelbeck DM, Mahasreshti PJ, Leath CA, Barker S, Yamaoto M, Li F, Alvarez RD, Curiel DT. Transcriptional targeting of tumors with a novel tumor-specific survivin promoter. Cancer Gene Therapy. 11: 256-62. PMID 15017380 DOI: 10.1038/sj.cgt.7700679  1
2004 Grandi P, Wang S, Schuback D, Krasnykh V, Spear M, Curiel DT, Manservigi R, Breakefield XO. HSV-1 virions engineered for specific binding to cell surface receptors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 419-27. PMID 15006609 DOI: 10.1016/j.ymthe.2003.12.010  1
2004 Wu H, Han T, Lam JT, Leath CA, Dmitriev I, Kashentseva E, Barnes MN, Alvarez RD, Curiel DT. Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy Gene Therapy. 11: 874-878. PMID 14999229 DOI: 10.1038/sj.gt.3302249  1
2004 Timares L, Douglas JT, Tillman BW, Krasnykh V, Curiel DT. Adenovirus-mediated gene delivery to dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 246: 139-54. PMID 14970589  1
2004 Bonner JA, Buchsbaum DJ, Rogers BE, Grizzle WE, Trummell HQ, Curiel DT, Fiveash JB, Ove R, Raisch KP. Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells. International Journal of Radiation Oncology, Biology, Physics. 58: 950-8. PMID 14967455 DOI: 10.1016/j.ijrobp.2003.09.095  1
2004 Nettelbeck DM, Rivera AA, Kupsch J, Dieckmann D, Douglas JT, Kontermann RE, Alemany R, Curiel DT. Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA. International Journal of Cancer. Journal International Du Cancer. 108: 136-45. PMID 14618628 DOI: 10.1002/ijc.11563  1
2003 Kawakami Y, Curiel TJ, Curiel DT. Cancer gene therapy and immunotherapy. Cancer Chemotherapy and Biological Response Modifiers. 21: 327-37. PMID 15338753 DOI: 10.1016/s0921-4410(03)21016-4  0.44
2003 Korokhov N, Mikheeva G, Krendelshchikov A, Belousova N, Simonenko V, Krendelshchikova V, Pereboev A, Kotov A, Kotova O, Triozzi PL, Aldrich WA, Douglas JT, Lo KM, Banerjee PT, Gillies SD, ... Curiel DT, et al. Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge. Journal of Virology. 77: 12931-40. PMID 14645549 DOI: 10.1128/JVI.77.24.12931-12940.2003  1
2003 Stam AG, Santegoets SJ, Westers TM, Sombroek CC, Janssen JJ, Tillman BW, van de Loosdrecht AA, Pinedo HM, Curiel DT, Ossenkoppele GJ, Scheper RJ, de Gruijl TD. CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation. British Journal of Cancer. 89: 1162-5. PMID 14520439 DOI: 10.1038/sj.bjc.6601225  1
2003 Kanerva A, Zinn KR, Chaudhuri TR, Lam JT, Suzuki K, Uil TG, Hakkarainen T, Bauerschmitz GJ, Wang M, Liu B, Cao Z, Alvarez RD, Curiel DT, Hemminki A. Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 449-58. PMID 12946318 DOI: 10.1016/S1525-0016(03)00200-4  1
2003 Contreras JL, Wu H, Smyth CA, Eckstein CP, Young CJ, Seki T, Bilbao G, Curiel DT, Eckhoff DE. Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets. Transplantation. 76: 252-61. PMID 12865820 DOI: 10.1097/01.TP.0000066361.02042.CA  1
2003 Barker SD, Dmitriev IP, Nettelbeck DM, Liu B, Rivera AA, Alvarez RD, Curiel DT, Hemminki A. Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma. Gene Therapy. 10: 1198-204. PMID 12833129 DOI: 10.1038/sj.gt.3301974  1
2003 Takayama K, Reynolds PN, Short JJ, Kawakami Y, Adachi Y, Glasgow JN, Rots MG, Krasnykh V, Douglas JT, Curiel DT. A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism. Virology. 309: 282-93. PMID 12758175 DOI: 10.1016/S0042-6822(03)00067-9  1
2003 Brandão JG, Scheper RJ, Lougheed SM, Curiel DT, Tillman BW, Gerritsen WR, van den Eertwegh AJ, Pinedo HM, Haisma HJ, de Gruijl TD. CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation. Vaccine. 21: 2268-72. PMID 12744857 DOI: 10.1016/S0264-410X(03)00050-1  1
2003 Noya F, Balagué C, Banerjee NS, Curiel DT, Broker TR, Chow LT. Activation of adenovirus early promoters and lytic phase in differentiated strata of organotypic cultures of human keratinocytes. Journal of Virology. 77: 6533-40. PMID 12743310 DOI: 10.1128/JVI.77.11.6533-6540.2003  1
2003 Lam JT, Bauerschmitz GJ, Kanerva A, Barker SD, Straughn JM, Wang M, Barnes MN, Blackwell JL, Siegal GP, Alvarez RD, Curiel DT, Hemminki A. Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids. Cancer Gene Therapy. 10: 377-87. PMID 12719707 DOI: 10.1038/sj.cgt.7700578  1
2003 Barker SD, Coolidge CJ, Kanerva A, Hakkarainen T, Yamamoto M, Liu B, Rivera AA, Bhoola SM, Barnes MN, Alvarez RD, Curiel DT, Hemminki A. The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy. The Journal of Gene Medicine. 5: 300-10. PMID 12692864 DOI: 10.1002/jgm.341  1
2003 Nagi P, Vickers SM, Davydova J, Adachi Y, Takayama K, Barker S, Krasnykh V, Curiel DT, Yamamoto M, Sugerman HJ. Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity enhancement Journal of Gastrointestinal Surgery. 7: 364-371. PMID 12654561 DOI: 10.1016/S1091-255X(02)00437-7  1
2003 Rots MG, Curiel DT, Gerritsen WR, Haisma HJ. Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 87: 159-65. PMID 12618032 DOI: 10.1016/S0168-3659(02)00360-7  0.48
2003 Arafat WO, Buchsbaum DJ, Gómez-Navarro J, Tawil SA, Olsen C, Xiang J, El-Akad H, Salama AM, Badib AO, Stackhouse MA, Curiel DT. An adenovirus encoding proapoptotic Bax synergistically radiosensitizes malignant glioma. International Journal of Radiation Oncology, Biology, Physics. 55: 1037-50. PMID 12605984 DOI: 10.1016/S0360-3016(02)04488-7  1
2003 Hemminki A, Kanerva A, Kremer EJ, Bauerschmitz GJ, Smith BF, Liu B, Wang M, Desmond RA, Keriel A, Barnett B, Baker HJ, Siegal GP, Curiel DT. A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 163-73. PMID 12597904 DOI: 10.1016/S1525-0016(02)00049-7  1
2003 Hakkarainen T, Hemminki A, Pereboev AV, Barker SD, Asiedu CK, Strong TV, Kanerva A, Wahlfors J, Curiel DT. CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 619-24. PMID 12576427  1
2003 Uil TG, Seki T, Dmitriev I, Kashentseva E, Douglas JT, Rots MG, Middeldorp JM, Curiel DT. Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob. Cancer Gene Therapy. 10: 121-4. PMID 12536200 DOI: 10.1038/sj.cgt.7700543  1
2002 Wu H, Dmitriev I, Kashentseva E, Seki T, Wang M, Curiel DT. Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon. Journal of Virology. 76: 12775-82. PMID 12438602 DOI: 10.1128/JVI.76.24.12775-12782.2002  1
2002 Zhang HG, Xie J, Dmitriev I, Kashentseva E, Curiel DT, Hsu HC, Mountz JD. Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production. Journal of Virology. 76: 12023-31. PMID 12414944 DOI: 10.1128/JVI.76.23.12023-12031.2002  1
2002 Bilbao G, Contreras JL, Curiel DT. Genetically engineered intracellular single-chain antibodies in gene therapy. Molecular Biotechnology. 22: 191-211. PMID 12405266 DOI: 10.1385/MB:22:2:191  1
2002 Sullivan DE, Mondelli MU, Curiel DT, Krasnykh V, Mikheeva G, Gaglio P, Morris CB, Dash S, Gerber MA. Construction and characterization of an intracellular single-chain human antibody to hepatitis C virus non-structural 3 protein. Journal of Hepatology. 37: 660-8. PMID 12399234 DOI: 10.1016/S0168-8278(02)00270-2  1
2002 de Gruijl TD, Luykx-de Bakker SA, Tillman BW, van den Eertwegh AJ, Buter J, Lougheed SM, van der Bij GJ, Safer AM, Haisma HJ, Curiel DT, Scheper RJ, Pinedo HM, Gerritsen WR. Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors. Journal of Immunology (Baltimore, Md. : 1950). 169: 5322-31. PMID 12391253  1
2002 Barnett BG, Tillman BW, Curiel DT, Douglas JT. Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 377-85. PMID 12231174 DOI: 10.1006/mthe.2002.0670  1
2002 Wu H, Seki T, Dmitriev I, Uil T, Kashentseva E, Han T, Curiel DT. Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirus-adenovirus receptor-independent gene transfer efficiency. Human Gene Therapy. 13: 1647-53. PMID 12228019 DOI: 10.1089/10430340260201734  1
2002 Witlox MA, Van Beusechem VW, Grill J, Haisma HJ, Schaap G, Bras J, Van Diest P, De Gast A, Curiel DT, Pinedo HM, Gerritsen WR, Wuisman PI. Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma. The Journal of Gene Medicine. 4: 510-6. PMID 12221644 DOI: 10.1002/jgm.308  0.48
2002 Kim M, Zinn KR, Barnett BG, Sumerel LA, Krasnykh V, Curiel DT, Douglas JT. The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells. European Journal of Cancer (Oxford, England : 1990). 38: 1917-26. PMID 12204675 DOI: 10.1016/S0959-8049(02)00131-4  1
2002 Kaliberov SA, Buchsbaum DJ, Gillespie GY, Curiel DT, Arafat WO, Carpenter M, Stackhouse MA. Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 190-8. PMID 12161185 DOI: 10.1006/mthe.2002.0648  1
2002 Bilbao G, Contreras JL, Dmitriev I, Smyth CA, Jenkins S, Eckhoff D, Thomas F, Thomas J, Curiel DT. Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 237-43. PMID 12096786 DOI: 10.1034/j.1600-6143.2002.20308.x  0.52
2002 Hemminki A, Zinn KR, Liu B, Chaudhuri TR, Desmond RA, Rogers BE, Barnes MN, Alvarez RD, Curiel DT. In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus. Journal of the National Cancer Institute. 94: 741-9. PMID 12011224 DOI: 10.1093/jnci/94.10.741  1
2002 Zinn KR, Chaudhuri TR, Krasnykh VN, Buchsbaum DJ, Belousova N, Grizzle WE, Curiel DT, Rogers BE. Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice. Radiology. 223: 417-25. PMID 11997547 DOI: 10.1148/radiol.2232010501  1
2002 Zhang HG, Xie J, Xu L, Yang P, Xu X, Sun S, Wang Y, Curiel DT, Hsu HC, Mountz JD. Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver. Journal of Virology. 76: 5692-700. PMID 11991997 DOI: 10.1128/JVI.76.11.5692-5700.2002  1
2002 Arafat WO, Gómez-Navarro J, Buchsbaum DJ, Xiang J, Wang M, Casado E, Barker SD, Mahasreshti PJ, Haisma HJ, Barnes MN, Siegal GP, Alvarez RD, Hemminki A, Nettelbeck DM, Curiel DT. Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv. Gene Therapy. 9: 256-62. PMID 11896464 DOI: 10.1038/sj.gt.3301639  1
2002 Kanerva A, Mikheeva GV, Krasnykh V, Coolidge CJ, Lam JT, Mahasreshti PJ, Barker SD, Straughn M, Barnes MN, Alvarez RD, Hemminki A, Curiel DT. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 275-80. PMID 11801569  1
2002 Holm PS, Bergmann S, Jürchott K, Lage H, Brand K, Ladhoff A, Mantwill K, Curiel DT, Dobbelstein M, Dietel M, Gänsbacher B, Royer HD. YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter Journal of Biological Chemistry. 277: 10427-10434. PMID 11788582 DOI: 10.1074/jbc.M106955200  1
2002 Seki T, Dmitriev I, Kashentseva E, Takayama K, Rots M, Suzuki K, Curiel DT. Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines. Journal of Virology. 76: 1100-8. PMID 11773386 DOI: 10.1128/JVI.76.3.1100-1108.2002  0.52
2001 Zou W, Machelon V, Coulomb-L'Hermin A, Borvak J, Nome F, Isaeva T, Wei S, Krzysiek R, Durand-Gasselin I, Gordon A, Pustilnik T, Curiel DT, Galanaud P, Capron F, Emilie D, et al. Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nature Medicine. 7: 1339-46. PMID 11726975 DOI: 10.1038/nm1201-1339  1
2001 Hemminki A, Belousova N, Zinn KR, Liu B, Wang M, Chaudhuri TR, Rogers BE, Buchsbaum DJ, Siegal GP, Barnes MN, Gomez-Navarro J, Curiel DT, Alvarez RD. An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 223-31. PMID 11545613 DOI: 10.1006/mthe.2001.0446  0.32
2001 Ponnazhagan S, Mahendra G, Curiel DT, Shaw DR. Adeno-associated virus type 2-mediated transduction of human monocyte-derived dendritic cells: Implications for ex vivo immunotherapy Journal of Virology. 75: 9493-9501. PMID 11533211 DOI: 10.1128/JVI.75.19.9493-9501.2001  1
2001 Casado E, Gomez-Navarro J, Yamamoto M, Adachi Y, Coolidge CJ, Arafat WO, Barker SD, Wang MH, Mahasreshti PJ, Hemminki A, Gonzalez-Baron M, Barnes MN, Pustilnik TB, Siegal GP, Alvarez RD, ... Curiel DT, et al. Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 2496-504. PMID 11489832  1
2001 Balagué C, Noya F, Alemany R, Chow LT, Curiel DT. Human papillomavirus E6E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organotypic cultures of human keratinocytes. Journal of Virology. 75: 7602-11. PMID 11462032 DOI: 10.1128/JVI.75.16.7602-7611.2001  1
2001 Barker SD, Casado E, Gomez-Navarro J, Xiang J, Arafat W, Mahasreshti P, Pustilnik TB, Hemminki A, Siegal GP, Alvarez RD, Curiel DT. An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites. Gynecologic Oncology. 82: 57-63. PMID 11426962 DOI: 10.1006/gyno.2001.6226  1
2001 Zhang HG, Wang YM, Xie JF, Liang X, Hsu HC, Zhang X, Douglas J, Curiel DT, Mountz JD. Recombinant adenovirus expressing adeno-associated virus cap and rep proteins supports production of high-titer recombinant adeno-associated virus Gene Therapy. 8: 704-712. PMID 11406765 DOI: 10.1038/sj.gt.3301454  1
2001 Contreras JL, Bilbao G, Smyth CA, Jiang XL, Eckhoff DE, Jenkins SM, Thomas FT, Curiel DT, Thomas JM. Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene. Transplantation. 71: 1015-23. PMID 11374395 DOI: 10.1097/00007890-200104270-00001  1
2000 Reynolds PN, Zinn KR, Gavrilyuk VD, Balyasnikova IV, Rogers BE, Buchsbaum DJ, Wang MH, Miletich DJ, Grizzle WE, Douglas JT, Danilov SM, Curiel DT. A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 562-78. PMID 11124057 DOI: 10.1006/mthe.2000.0205  1
2000 Tillman BW, Hayes TL, DeGruijl TD, Douglas JT, Curiel DT. Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model. Cancer Research. 60: 5456-63. PMID 11034088  1
2000 Blackwell JL, Hui L, Gomez-Navarro J, Dmitriev I, Krasnykh V, Richter CA, Shaw DR, Alvarez RD, Curiel DT, Strong TV. Using a tropism-modified adenoviral vector to circumvent inhibitory factors in ascites fluid Human Gene Therapy. 11: 1657-1669. PMID 10954900 DOI: 10.1089/10430340050111313  1
2000 Zhang HG, Huang N, Liu D, Bilbao L, Zhang X, Yang P, Zhou T, Curiel DT, Mountz JD. Gene therapy that inhibits nuclear translocation of nuclear factor κB results in tumor necrosis factor α-induced apoptosis of human synovial fibroblasts Arthritis and Rheumatism. 43: 1094-1105. PMID 10817564 DOI: 10.1002/1529-0131(200005)43:5<1094::AID-ANR20>3.0.CO;2-V  1
2000 Xiang J, Gómez-Navarro J, Arafat W, Liu B, Barker SD, Alvarez RD, Siegal GP, Curiel DT. Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer. The Journal of Gene Medicine. 2: 97-106. PMID 10809143 DOI: 10.1002/(SICI)1521-2254(200003/04)2:2<97::AID-JGM99>3.0.CO;2-S  1
2000 Zhang HG, Fleck M, Kern ER, Liu D, Wang Y, Hsu HC, Yang P, Wang Z, Curiel DT, Zhou T, Mountz JD. Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice. The Journal of Clinical Investigation. 105: 813-21. PMID 10727450 DOI: 10.1172/JCI8236  0.4
2000 Gómez-Navarro J, Contreras JL, Arafat W, Jiang XL, Krisky D, Oligino T, Marconi P, Hubbard B, Glorioso JC, Curiel DT, Thomas JM. Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. Gene Therapy. 7: 43-52. PMID 10680015 DOI: 10.1038/sj.gt.3301054  1
1999 Gómez-Navarro J, Curiel DT, Douglas JT. Gene therapy for cancer. European Journal of Cancer (Oxford, England : 1990). 35: 2039-57. PMID 10711245 DOI: 10.1016/S0959-8049(99)00300-7  1
1999 Gómez-Navarro J, Curiel DT, Douglas JT. Gene therapy for cancer. European Journal of Cancer (Oxford, England : 1990). 35: 867-85. PMID 10533466 DOI: 10.1016/S0959-8049(99)00061-1  1
1999 Haisma HJ, Pinedo HM, Rijswijk A, der Meulen-Muileman I, Sosnowski BA, Ying W, Beusechem VW, Tillman BW, Gerritsen WR, Curiel DT. Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM. Gene Therapy. 6: 1469-74. PMID 10467371 DOI: 10.1038/sj.gt.3300969  1
1999 Thomas FT, Contreras JL, Bilbao G, Ricordi C, Curiel D, Thomas JM. Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation. Surgery. 126: 299-304. PMID 10455898 DOI: 10.1016/S0039-6060(99)70169-8  1
1999 Bilbao G, Contreras JL, Eckhoff DE, Mikheeva G, Krasnykh V, Douglas JT, Thomas FT, Thomas JM, Curiel DT. Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene. Annals of Surgery. 230: 185-93. PMID 10450732 DOI: 10.1097/00000658-199908000-00008  1
1999 Blackwell JL, Miller CR, Douglas JT, Li H, Reynolds PN, Carroll WR, Peters GE, Strong TV, Curiel DT. Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma. Archives of Otolaryngology--Head & Neck Surgery. 125: 856-63. PMID 10448731  1
1999 Shi Z, Curiel DT, Tang DC. DNA-based non-invasive vaccination onto the skin. Vaccine. 17: 2136-41. PMID 10367946 DOI: 10.1016/S0264-410X(98)00488-5  1
1999 Stackhouse MA, Buchsbaum DJ, Kancharla SR, Grizzle WE, Grimes C, Laffoon K, Pederson LC, Curiel DT. Specific membrane receptor gene expression targeted with radiolabeled peptide employing the erbB-2 and DF3 promoter elements in adenoviral vectors Cancer Gene Therapy. 6: 209-219. PMID 10359206 DOI: 10.1038/sj.cgt.7700049  1
1999 Tillman BW, de Gruijl TD, Luykx-de Bakker SA, Scheper RJ, Pinedo HM, Curiel TJ, Gerritsen WR, Curiel DT. Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector. Journal of Immunology (Baltimore, Md. : 1950). 162: 6378-83. PMID 10352250  1
1999 Douglas JT, Miller CR, Kim M, Dmitriev I, Mikheeva G, Krasnykh V, Curiel DT. A system for the propagation of adenoviral vectors with genetically modified receptor specificities. Nature Biotechnology. 17: 470-5. PMID 10331807 DOI: 10.1038/8647  1
1999 Bilbao G, Contreras JL, Gómez-Navarro J, Eckhoff DE, Mikheeva G, Krasnykh V, Hynes T, Thomas FT, Thomas JM, Curiel DT. Genetic modification of liver grafts with an adenoviral vector encoding the Bcl-2 gene improves organ preservation. Transplantation. 67: 775-83. PMID 10199723 DOI: 10.1097/00007890-199903270-00001  0.32
1999 Bilbao G, Contreras JL, Mikheeva G, Krasnykh V, Eckhoff DE, Thomas FT, Thomas J, Curiel DT. Genetic cytoprotection of human endothelial cells during preservation time with an adenoviral vector encoding the anti-apoptotic human Bcl-2 gene. Transplantation Proceedings. 31: 1012-5. PMID 10083450 DOI: 10.1016/S0041-1345(98)01880-6  0.32
1999 Bilbao G, Zhang H, Contreras JL, Zhou T, Feng M, Saito I, Mountz JD, Curiel DT. Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system Transplantation Proceedings. 31: 792-793. PMID 10083340 DOI: 10.1016/S0041-1345(98)01771-0  1
1999 Bilbao G, Contreras JL, Curiel DT. Advances in cancer gene therapy Expert Opinion On Therapeutic Patents. 9: 711-736. DOI: 10.1517/13543776.9.6.711  1
1998 Stackhouse MA, Buchsbaum DJ, Grizzle WE, Bright SJ, Olsen CC, Kancharla S, Mayo MS, Curiel DT. Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo. International Journal of Radiation Oncology, Biology, Physics. 42: 817-22. PMID 9845103 DOI: 10.1016/S0360-3016(98)00330-7  1
1998 Pederson LC, Vickers SM, Buchsbaum DJ, Kancharla SR, Mayo MS, Curiel DT, Stackhouse MA. Combined Cytosine Deaminase Expression, 5-Fluorocytosine Exposure, and Radiotherapy Increases Cytotoxicity to Cholangiocarcinoma Cells Journal of Gastrointestinal Surgery. 2: 283-291. PMID 9841986 DOI: 10.1016/S1091-255X(98)80024-3  1
1998 Suzuki T, Piche A, Kasono K, Xiang J, Gomez-Navarro J, Moriuchi S, Krisky DM, Oligino T, Glorioso JC, Curiel TJ, Curiel DT. Efficient gene delivery into epstein-barr virus (EBV)-transformed human B cells mediated by replication-defective herpes simplex virus-1 (HSV-1): A gene therapy model for EBV-related B cell malignancy. Biochemical and Biophysical Research Communications. 252: 686-90. PMID 9837767 DOI: 10.1006/bbrc.1998.9685  1
1998 Zhang HG, Liu D, Heike Y, Yang P, Wang Z, Wang X, Curiel DT, Zhou T, Mountz JD. Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand - Producing antigen presenting cells Nature Biotechnology. 16: 1045-1049. PMID 9831033 DOI: 10.1038/3488  1
1998 Wang M, Rancourt C, Navarro JG, Krisky D, Marconi P, Oligino T, Alvarez RD, Siegal GP, Glorioso JC, Curiel DT. High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector. Gynecologic Oncology. 71: 278-87. PMID 9826472 DOI: 10.1006/gyno.1998.5132  1
1998 Zhang HG, Zhou T, Yang P, Edwards CK, Curiel DT, Mountz JD. Inhibition of tumor necrosis factor α decreases inflammation and prolongs adenovirus gene expression in lung and liver Human Gene Therapy. 9: 1875-1884. PMID 9741426 DOI: 10.1089/hum.1998.9.13-1875  1
1998 Grim J, Deshane J, Siegal GP, Alvarez RD, DiFiore P, Curiel DT. The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv Journal of Molecular Medicine. 76: 451-458. PMID 9625302 DOI: 10.1007/s001090050237  1
1998 Simmons WL, Rivera KE, Curiel DT, Williams WF, Olman MA. Adenovirally mediated gene transfer of functional human tissue-type plasminogen activator to murine lungs. American Journal of Respiratory Cell and Molecular Biology. 18: 307-14. PMID 9490648 DOI: 10.1165/ajrcmb.18.3.2892  1
1997 Tang DC, Jennelle RS, Shi Z, Garver RI, Carbone DP, Loya F, Chang CH, Curiel DT. Overexpression of adenovirus-encoded transgenes from the cytomegalovirus immediate early promoter in irradiated tumor cells. Human Gene Therapy. 8: 2117-24. PMID 9414259 DOI: 10.1089/hum.1997.8.17-2117  1
1997 Rogers BE, Curiel DT, Mayo MS, Laffoon KK, Bright SJ, Buchsbaum DJ. Tumor localization of a radiolabeled bombesin analogue in mice bearing human ovarian tumors induced to excess the gastrin-releasing peptide receptor by an adenoviral vector Cancer. 80: 2419-2424. PMID 9406692 DOI: 10.1002/(SICI)1097-0142(19971215)80:12+<2419::AID-CNCR13>3.0.CO;2-F  1
1997 Feng M, Jackson WH, Goldman CK, Rancourt C, Wang M, Dusing SK, Siegal G, Curiel DT. Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector Nature Biotechnology. 15: 866-870. PMID 9306401 DOI: 10.1038/nbt0997-866  1
1997 Vickers SM, Sampson LS, Phillips JO, Eckhoff D, Kerby JD, Sekar MC, Curiel DT, Thompson JA. Adenoviral vector infection of the human exocrine pancreas. Archives of Surgery (Chicago, Ill. : 1960). 132: 1006-9. PMID 9301614 DOI: 10.1001/archsurg.1997.01430330072012  1
1997 Douglas JT, Curiel DT. Strategies to accomplish targeted gene delivery to muscle cells employing tropism-modified adenoviral vectors. Neuromuscular Disorders : Nmd. 7: 284-98. PMID 9267842 DOI: 10.1016/S0960-8966(97)00053-9  1
1997 Bilbao G, Feng M, Rancourt C, Jackson WH, Curiel DT. Adenoviral/retroviral vector chimeras: A novel strategy to achieve high- efficiency stable transduction in vivo Faseb Journal. 11: 624-634. PMID 9240964 DOI: 10.1096/fasebj.11.8.9240964  1
1997 Deshane J, Siegal GP, Wang M, Wright M, Bucy RP, Alvarez RD, Curiel DT. Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy. Gynecologic Oncology. 64: 378-85. PMID 9062138 DOI: 10.1006/gyno.1996.4566  1
1997 Kim M, Wright M, Deshane J, Accavitti MA, Tilden A, Saleh M, Vaughan WP, Carabasi MH, Rogers MD, Hockett RD, Grizzle WE, Curiel DT. A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow. Human Gene Therapy. 8: 157-70. PMID 9017419 DOI: 10.1089/hum.1997.8.2-157  1
1997 Barnes MN, Deshane JS, Rosenfeld M, Siegal GP, Curiel DT, Alvarez RD. Gene therapy and ovarian cancer: A review Obstetrics and Gynecology. 89: 145-155. PMID 8990458 DOI: 10.1016/S0029-7844(96)00296-7  1
1996 Douglas JT, Rogers BE, Rosenfeld ME, Michael SI, Feng M, Curiel DT. Targeted gene delivery by tropism-modified adenoviral vectors. Nature Biotechnology. 14: 1574-8. PMID 9634824 DOI: 10.1038/nbt1196-1574  1
1996 Grim J, Deshane J, Feng M, Lieber A, Kay M, Curiel DT. erbB-2 Knockout Employing an Intracellular Single-chain Antibody (sFv) Accomplishes Specific Toxicity in erbB-2-expressing Lung Cancer Cells American Journal of Respiratory Cell and Molecular Biology. 15: 348-354. PMID 8810638 DOI: 10.1165/ajrcmb.15.3.8810638  1
1995 Deshane J, Siegal GP, Alvarez RD, Wang MH, Feng M, Cabrera G, Liu T, Kay M, Curiel DT. Targeted tumor killing via an intracellular antibody against erbB-2 Journal of Clinical Investigation. 96: 2980-2989. PMID 8675670 DOI: 10.1172/JCI118370  1
1995 Deshane J, Cabrera G, Grim JE, Siegal GP, Pike J, Alvarez RD, Curiel DT. Targeted Eradication of Ovarian Cancer Mediated by Intracellular Expression of Anti-erbB-2 Single-Chain Antibody Gynecologic Oncology. 59: 8-14. PMID 7557620 DOI: 10.1006/gyno.1995.1260  1
1994 Lozier JN, Thompson AR, Hu PC, Read M, Brinkhous KM, High KA, Curiel DT. Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes Human Gene Therapy. 5: 313-322. PMID 8018746 DOI: 10.1089/hum.1994.5.3-313  1
1994 Curiel DT, Huber BE, Meruelo D, Shepard N, Ledley FD, Mazumder A, Chiou H. High-efficiency gene transfer mediated by adenovirus-polylysine-DNA complexes Annals of the New York Academy of Sciences. 716: 36-58. PMID 7912914 DOI: 10.1111/j.1749-6632.1994.tb21702.x  1
1994 Goldsmith KT, Curiel DT, Engler JA, Garver RI. Trans complementation of an E1A-deleted adenovirus with codelivered E1A sequences to make recombinant adenoviral producer cells Human Gene Therapy. 5: 1341-1348. PMID 7893805 DOI: 10.1089/hum.1994.5.11-1341  1
1994 Cook DR, Maxwell IH, Glode LM, Maxwell F, Stevens JO, Purner MB, Wagner E, Curiel DT, Curiel TJ. Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. Cancer Biotherapy. 9: 131-41. PMID 7812362 DOI: 10.1089/cbr.1994.9.131  1
1992 Curiel DT, Agarwal S, Rømer MU, Wagner E, Cotten M, Birnstiel ML, Boucher RC. Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway. American Journal of Respiratory Cell and Molecular Biology. 6: 247-252. PMID 1540389 DOI: 10.1165/ajrcmb/6.3.247  1
1992 Curiel DT, Wagner E, Gotten M, Birnstiel ML, Agarwal S, Cheng-Ming LI, Loechel S, Hu PC. High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes Human Gene Therapy. 3: 147-154. PMID 1391034 DOI: 10.1089/hum.1992.3.2-147  1
Show low-probability matches.