David T. Curiel - Publications

Affiliations: 
Medicine University of Alabama, Birmingham, Birmingham, AL, United States 

224 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 González-Pastor R, Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Lu ZH, Goedegebuure SP, Podhajcer OL, Curiel DT. Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents. Journal of Ovarian Research. 12: 18. PMID 30767772 DOI: 10.1186/s13048-019-0493-5  0.32
2018 Chondronasiou D, Eisden TTHD, Stam AGM, Matthews QL, Icyuz M, Hooijberg E, Dmitriev I, Curiel DT, de Gruijl TD, van de Ven R. Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs. Vaccines. 6. PMID 30022005 DOI: 10.3390/vaccines6030042  0.6
2017 Kuroki LM, Jin X, Dmitriev IP, Kashentseva EA, Powell MA, Mutch DG, Dietz AB, Curiel DT, Hawkins WG, Spitzer D. Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer. Plos One. 12: e0190125. PMID 29267342 DOI: 10.1371/journal.pone.0190125  0.32
2017 Sharma PK, Dmitriev IP, Kashentseva EA, Raes G, Li L, Kim SW, Lu ZH, Arbeit JM, Fleming TP, Kaliberov SA, Goedegebuure SP, Curiel DT, Gillanders WE. Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Therapy. PMID 29242639 DOI: 10.1038/s41417-017-0002-1  0.32
2017 Naoum GE, Zhu ZB, Buchsbaum DJ, Curiel DT, Arafat WO. Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs. Clinical and Translational Medicine. 6: 11. PMID 28251571 DOI: 10.1186/s40169-017-0140-y  0.32
2016 Bhatia S, O'Bryan SM, Rivera AA, Curiel DT, Mathis JM. CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter. Oncolytic Virotherapy. 5: 99-113. PMID 27957479 DOI: 10.2147/OV.S112107  0.32
2016 Schmidt DJ, Beamer G, Tremblay JM, Steele JA, Kim HB, Wang Y, Debatis M, Sun X, Kashentseva EA, Dmitriev IP, Curiel DT, Shoemaker CB, Tzipori S. A Tetraspecific VHH-based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection. Clinical and Vaccine Immunology : Cvi. PMID 27413067 DOI: 10.1128/CVI.00730-15  0.32
2016 Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Curiel DT. Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer. Journal of Ovarian Research. 9: 38. PMID 27349517 DOI: 10.1186/s13048-016-0248-5  0.32
2016 Fonseca JA, Cabrera-Mora M, Kashentseva EA, Villegas JP, Fernandez A, Van Pelt A, Dmitriev IP, Curiel DT, Moreno A. A Plasmodium Promiscuous T Cell Epitope Delivered within the Ad5 Hexon Protein Enhances the Protective Efficacy of a Protein Based Malaria Vaccine. Plos One. 11: e0154819. PMID 27128437 DOI: 10.1371/journal.pone.0154819  0.32
2016 Buggio M, Towe C, Annan A, Kaliberov S, Lu ZH, Stephens C, Arbeit JM, Curiel DT. Pulmonary Vasculature Directed Adenovirus Increases Epithelial Lining Fluid Alpha-1 Antitrypsin Levels. The Journal of Gene Medicine. PMID 26825735 DOI: 10.1002/jgm.2874  0.6
2016 Moayeri M, Tremblay JM, Debatis M, Dmietriev IP, Kashentseva EA, Yeh AJ, Cheung GY, Curiel DT, Leppla S, Shoemaker CB. Adenoviral expression of a bispecific VHH-based neutralizing agent targeting protective antigen provides prophylactic protection from anthrax in mice. Clinical and Vaccine Immunology : Cvi. PMID 26740390 DOI: 10.1128/CVI.00611-15  0.32
2015 Dobbins GC, Ugai H, Curiel DT, Gillespie GY. A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. Plos One. 10: e0145272. PMID 26689910 DOI: 10.1371/journal.pone.0145272  0.6
2015 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 22: 222. PMID 25904493 DOI: 10.1038/cgt.2015.13  0.6
2015 Ghisays F, Brace CS, Yackly SM, Kwon HJ, Mills KF, Kashentseva E, Dmitriev IP, Curiel DT, Imai SI, Ellenberger T. The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs. Cell Reports. PMID 25772354 DOI: 10.1016/j.celrep.2015.02.036  0.6
2015 Weber HL, Gidekel M, Werbajh S, Salvatierra E, Rotondaro C, Sganga L, Haab GA, Curiel DT, Cafferata EG, Podhajcer OL. A Novel CDC25B Promoter-Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1665-74. PMID 25573380 DOI: 10.1158/1078-0432.CCR-14-2316  0.6
2015 Sheoran AS, Dmitriev IP, Kashentseva EA, Cohen O, Mukherjee J, Debatis M, Shearer J, Tremblay JM, Beamer G, Curiel DT, Shoemaker CB, Tzipori S. Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication. Infection and Immunity. 83: 286-91. PMID 25368111 DOI: 10.1128/IAI.02360-14  0.6
2015 Everett WH, Curiel DT. Gene therapy for radioprotection Cancer Gene Therapy. 22: 172-180. DOI: 10.1038/cgt.2015.8  0.6
2014 Liu L, Rogers BE, Aladyshkina N, Cheng B, Lokitz SJ, Curiel DT, Mathis JM. Construction and Radiolabeling of Adenovirus Variants that Incorporate Human Metallothionein into Protein IX for Analysis of Biodistribution. Molecular Imaging. 13: 7290201400022. PMID 28650294 DOI: 10.2310/7290.2014.00022  0.32
2014 Dmitriev IP, Kashentseva EA, Kim KH, Matthews QL, Krieger SS, Parry JJ, Nguyen KN, Akers WJ, Achilefu S, Rogers BE, Alvarez RD, Curiel DT. Monitoring of Biodistribution and Persistence of Conditionally Replicative Adenovirus in a Murine Model of Ovarian Cancer Using Capsid-Incorporated mCherry and Expression of Human Somatostatin Receptor Subtype 2 Gene. Molecular Imaging. 13: 7290201400024. PMID 28650284 DOI: 10.2310/7290.2014.00024  0.6
2014 Dmitriev IP, Kashentseva EA, Kim KH, Matthews QL, Krieger SS, Parry JJ, Nguyen KN, Akers WJ, Achilefu S, Rogers BE, Alvarez RD, Curiel DT. Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene. Molecular Imaging. 13. PMID 25249483 DOI: 10.2310/7290.2014.00024  0.6
2014 Kawamura YI, Adachi Y, Curiel DT, Kawashima R, Kannagi R, Nishimoto N, Dohi T. Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer. Cancer Gene Therapy. 21: 427-33. PMID 25213663 DOI: 10.1038/cgt.2014.46  0.6
2014 Lewis TB, Glasgow JN, Harms AS, Standaert DG, Curiel DT. Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses. 6: 3293-310. PMID 25196484 DOI: 10.3390/v6083293  0.6
2014 Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB. Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein. Plos One. 9: e106422. PMID 25170904 DOI: 10.1371/journal.pone.0106422  0.32
2014 Liu L, Rogers BE, Aladyshkina N, Cheng B, Lokitz SJ, Curiel DT, Mathis JM. Construction and radiolabeling of adenovirus variants that incorporate human metallothionein into protein IX for analysis of biodistribution. Molecular Imaging. 13. PMID 25060486 DOI: DOI 10.2310/7290.2014.00022  0.6
2014 Lu ZH, Kaliberov S, Zhang J, Muz B, Azab AK, Sohn RE, Kaliberova L, Du Y, Curiel DT, Arbeit JM. The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 881-92. PMID 24955893 DOI: 10.1038/labinvest.2014.78  0.6
2014 Kaliberov SA, Kaliberova LN, Buggio M, Tremblay JM, Shoemaker CB, Curiel DT. Adenoviral targeting using genetically incorporated camelid single variable domains. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 893-905. PMID 24933423 DOI: 10.1038/labinvest.2014.82  0.6
2014 Sandey M, Bird RC, Das SK, Sarkar D, Curiel DT, Fisher PB, Smith BF. Characterization of the canine mda-7 gene, transcripts and expression patterns. Gene. 547: 23-33. PMID 24865935 DOI: 10.1016/j.gene.2014.05.054  0.6
2014 Uchino J, Curiel DT, Ugai H. Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes. Plos One. 9: e87342. PMID 24503714 DOI: 10.1371/journal.pone.0087342  0.6
2014 Azab BM, Dash R, Das SK, Bhutia SK, Sarkar S, Shen XN, Quinn BA, Dent P, Dmitriev IP, Wang XY, Curiel DT, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV). Journal of Cellular Physiology. 229: 34-43. PMID 23868767 DOI: 10.1002/jcp.24408  0.6
2014 Kaliberov SA, Kaliberova LN, Buchsbaum DJ, Curiel DT. Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus Cancer Gene Therapy. 21: 264-274. DOI: 10.1038/cgt.2014.26  0.6
2013 Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Curiel DT, Arbeit JM. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice. Plos One. 8: e83933. PMID 24376772 DOI: 10.1371/journal.pone.0083933  0.6
2013 Kaliberov SA, Kaliberova LN, Hong Lu Z, Preuss MA, Barnes JA, Stockard CR, Grizzle WE, Arbeit JM, Curiel DT. Retargeting of gene expression using endothelium specific hexon modified adenoviral vector. Virology. 447: 312-25. PMID 24210128 DOI: 10.1016/j.virol.2013.09.020  0.6
2013 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 20: 445-52. PMID 23928733 DOI: 10.1038/cgt.2013.39  0.6
2013 Nair S, Saed GM, Atta HM, Rajaratnam V, Diamond MP, Curiel DT, Al-Hendy A. Towards gene therapy of postoperative adhesions: fiber and transcriptional modifications enhance adenovirus targeting towards human adhesion cells. Gynecologic and Obstetric Investigation. 76: 119-24. PMID 23920223 DOI: 10.1159/000353426  0.6
2013 Nair S, Curiel DT, Rajaratnam V, Thota C, Al-Hendy A. Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas Human Reproduction. 28: 2398-2406. PMID 23820419 DOI: 10.1093/humrep/det275  0.6
2013 Kim KH, Dmitriev IP, Saddekni S, Kashentseva EA, Harris RD, Aurigemma R, Bae S, Singh KP, Siegal GP, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer. Gynecologic Oncology. 130: 518-24. PMID 23756180 DOI: 10.1016/j.ygyno.2013.06.003  0.6
2013 Viale DL, Cafferata EG, Gould D, Rotondaro C, Chernajovsky Y, Curiel DT, Podhajcer OL, Lopez MV. Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironment. The Journal of Investigative Dermatology. 133: 2576-84. PMID 23604101 DOI: 10.1038/jid.2013.191  0.6
2013 Kim JW, Glasgow JN, Nakayama M, Ak F, Ugai H, Curiel DT. An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer. Plos One. 8: e55533. PMID 23383334 DOI: 10.1371/journal.pone.0055533  0.6
2013 Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC). Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 758-66. PMID 23319057 DOI: 10.1038/mt.2012.282  0.6
2013 Alberti MO, Deshane JS, Chaplin DD, Pereboeva L, Curiel DT, Roth JC. A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism. Gene Therapy. 20: 733-41. PMID 23171918 DOI: 10.1038/gt.2012.91  0.6
2013 Oosterhoff D, Curiel DT, De Gruijl TD. Antigen targeting to dendritic cells for cancer immunotherapy Cancer Immunotherapy: Paradigms, Practice and Promise. 2147483647: 147-171. DOI: 10.1007/978-1-4614-4732-0_6  0.6
2013 Mahalingam D, Brumlik MJ, Waehler R, Curiel DT, Curiel TJ. Targeted toxins in cancer immunotherapy Cancer Immunotherapy: Paradigms, Practice and Promise. 2147483647: 377-396. DOI: 10.1007/978-1-4614-4732-0_12  0.6
2013 Martínez-Flores F, Barrera-López A, Sandoval-Zamora HE, García-Cavazos R, Franco-Bourland RE, Madinaveitia-V JA, Zentella-Dehesa A, Curiel DT, Sakamoto K. Activity of Egr-1 promoter induced by UV light in human primary dermal fibroblasts transduced with Ad-Egr-1/Luc is repressed by betamethasone Gene Therapy and Molecular Biology. 15: 92-106.  0.6
2012 Flatt JW, Fox TL, Makarova N, Blackwell JL, Dmitriev IP, Kashentseva EA, Curiel DT, Stewart PL. CryoEM visualization of an adenovirus capsid-incorporated HIV antigen. Plos One. 7: e49607. PMID 23166728 DOI: 10.1371/journal.pone.0049607  0.6
2012 Williams BJ, Bhatia S, Adams LK, Boling S, Carroll JL, Li XL, Rogers DL, Korokhov N, Kovesdi I, Pereboev AV, Curiel DT, Mathis JM. Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector. Plos One. 7: e46981. PMID 23056548 DOI: 10.1371/journal.pone.0046981  0.6
2012 Beatty MS, Curiel DT. Chapter two--Adenovirus strategies for tissue-specific targeting. Advances in Cancer Research. 115: 39-67. PMID 23021241 DOI: 10.1016/B978-0-12-398342-8.00002-1  0.6
2012 Lopez MV, Rivera AA, Viale DL, Benedetti L, Cuneo N, Kimball KJ, Wang M, Douglas JT, Zhu ZB, Bravo AI, Gidekel M, Alvarez RD, Curiel DT, Podhajcer OL. A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2222-33. PMID 22948673 DOI: 10.1038/mt.2012.147  0.6
2012 Chu QD, Sun G, Pope M, Luraguiz N, Curiel DT, Kim R, Li BD, Mathis JM. Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model. Surgery. 152: 441-8. PMID 22853858 DOI: 10.1016/j.surg.2012.05.040  0.6
2012 Ugai H, Dobbins GC, Wang M, Le LP, Matthews DA, Curiel DT. Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1. Virology. 432: 283-95. PMID 22717133 DOI: 10.1016/j.virol.2012.05.028  0.6
2012 Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. Plos One. 7: e37812. PMID 22624065 DOI: 10.1371/journal.pone.0037812  0.6
2012 Kim KH, Dmitriev I, O'Malley JP, Wang M, Saddekni S, You Z, Preuss MA, Harris RD, Aurigemma R, Siegal GP, Zinn KR, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3440-51. PMID 22510347 DOI: 10.1158/1078-0432.CCR-11-2852  0.6
2012 Hangalapura BN, Timares L, Oosterhoff D, Scheper RJ, Curiel DT, de Gruijl TD. CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic. The Journal of Gene Medicine. 14: 416-27. PMID 22228547 DOI: 10.1002/jgm.1648  0.44
2012 Azab B, Dash R, Das SK, Bhutia SK, Shen XN, Quinn BA, Sarkar S, Wang XY, Hedvat M, Dmitriev IP, Curiel DT, Grant S, Dent P, Reed JC, Pellecchia M, et al. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. Journal of Cellular Physiology. 227: 2145-53. PMID 21780116 DOI: 10.1002/jcp.22947  0.6
2012 Bhutia SK, Das SK, Kegelman TP, Azab B, Dash R, Su ZZ, Wang XY, Rizzi F, Bettuzzi S, Lee SG, Dent P, Grant S, Curiel DT, Sarkar D, Fisher PB. mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer. Journal of Cellular Physiology. 227: 1805-13. PMID 21732348 DOI: 10.1002/jcp.22904  0.6
2011 Quinn BA, Dash R, Azab B, Sarkar S, Das SK, Kumar S, Oyesanya RA, Dasgupta S, Dent P, Grant S, Rahmani M, Curiel DT, Dmitriev I, Hedvat M, Wei J, et al. Targeting Mcl-1 for the therapy of cancer. Expert Opinion On Investigational Drugs. 20: 1397-411. PMID 21851287 DOI: 10.1517/13543784.2011.609167  0.6
2011 Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine. Cancer Research. 71: 5827-37. PMID 21747119 DOI: 10.1158/0008-5472.CAN-11-0804  0.6
2011 Rein DT, Volkmer A, Beyer IM, Curiel DT, Janni W, Dragoi A, Hess AP, Maass N, Baldus SE, Bauerschmitz G, Breidenbach M. Treatment of chemotherapy resistant ovarian cancer with a MDR1 targeted oncolytic adenovirus. Gynecologic Oncology. 123: 138-46. PMID 21741695 DOI: 10.1016/j.ygyno.2011.06.007  0.6
2011 Dent P, Curiel DT, Fisher PB. The potential of virus-based gene therapies for treatment of metastatic kidney cancer. Expert Review of Anticancer Therapy. 11: 809-11. PMID 21707273 DOI: 10.1586/era.11.59  0.6
2011 Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, Lee SG, Dent P, Curiel DT, Sarkar D, Fisher PB. Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24). Autophagy. 7: 1076-7. PMID 21610321 DOI: 10.4161/auto.7.9.16163  0.6
2011 Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, et al. Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8785-90. PMID 21555592 DOI: 10.1073/pnas.1100769108  0.6
2011 Mathis JM, Bhatia S, Khandelwal A, Kovesdi I, Lokitz SJ, Odaka Y, Takalkar AM, Terry T, Curiel DT. Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging. Plos One. 6: e16792. PMID 21347423 DOI: 10.1371/journal.pone.0016792  0.6
2011 O'Neill AM, Smith AN, Spangler EA, Whitley EM, Schleis SE, Bird RC, Curiel DT, Thacker EE, Smith BF. Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins. Cancer Biology & Therapy. 11: 651-8. PMID 21321486 DOI: 10.4161/cbt.11.7.14690  0.6
2011 Dash R, Azab B, Shen XN, Sokhi UK, Sarkar S, Su ZZ, Wang XY, Claudio PP, Dent P, Dmitriev IP, Curiel DT, Grant S, Sarkar D, Fisher PB. Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Discovery Medicine. 11: 46-56. PMID 21276410  0.6
2011 Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine. Vaccine. 29: 2313-21. PMID 21272606 DOI: 10.1016/j.vaccine.2011.01.022  0.6
2011 Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients. Human Gene Therapy. 22: 821-8. PMID 21171861 DOI: 10.1089/hum.2010.180  0.6
2011 Park MA, Hamed HA, Mitchell C, Cruickshanks N, Dash R, Allegood J, Dmitriev IP, Tye G, Ogretmen B, Spiegel S, Yacoub A, Grant S, Curiel DT, Fisher PB, Dent P. A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. Molecular Pharmacology. 79: 368-80. PMID 21119025 DOI: 10.1124/mol.110.069484  0.6
2010 Kimball KJ, Preuss MA, Barnes MN, Wang M, Siegal GP, Wan W, Kuo H, Saddekni S, Stockard CR, Grizzle WE, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5277-87. PMID 20978148 DOI: 10.1158/1078-0432.CCR-10-0791  0.6
2010 Eulitt PJ, Park MA, Hossein H, Cruikshanks N, Yang C, Dmitriev IP, Yacoub A, Curiel DT, Fisher PB, Dent P. Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery. Cancer Biology & Therapy. 10: 1290-305. PMID 20948318 DOI: 10.4161/cbt.10.12.13497  0.6
2010 Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, ... ... Curiel DT, et al. mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine & Growth Factor Reviews. 21: 381-91. PMID 20926331 DOI: 10.1016/j.cytogfr.2010.08.004  0.6
2010 Lewis TB, Glasgow JN, Glandon AM, Curiel DT, Standaert DG. Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy. Plos One. 5. PMID 20862245 DOI: 10.1371/journal.pone.0012672  0.6
2010 Rahmani M, Mayo M, Dash R, Sokhi UK, Dmitriev IP, Sarkar D, Dent P, Curiel DT, Fisher PB, Grant S. Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress. Molecular Pharmacology. 78: 1096-104. PMID 20858700 DOI: 10.1124/mol.110.068007  0.6
2010 Murakami M, Ugai H, Wang M, Belousova N, Dent P, Fisher PB, Glasgow JN, Everts M, Curiel DT. An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations. Virology. 407: 196-205. PMID 20828776 DOI: 10.1016/j.virol.2010.08.010  0.6
2010 Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Molecular Cancer Therapeutics. 9: 2536-44. PMID 20736345 DOI: 10.1158/1535-7163.MCT-10-0332  0.6
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, ... ... Curiel DT, et al. The development of MDA-7/IL-24 as a cancer therapeutic. Pharmacology & Therapeutics. 128: 375-84. PMID 20732354 DOI: 10.1016/j.pharmthera.2010.08.001  0.6
2010 Pennington K, Chu QD, Curiel DT, Li BD, Mathis JM. The utility of a tissue slice model system to determine breast cancer infectivity by oncolytic adenoviruses. The Journal of Surgical Research. 163: 270-5. PMID 20691986 DOI: 10.1016/j.jss.2010.03.072  0.6
2010 Guardado-Calvo P, Muñoz EM, Llamas-Saiz AL, Fox GC, Kahn R, Curiel DT, Glasgow JN, van Raaij MJ. Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains. Journal of Virology. 84: 10558-68. PMID 20686025 DOI: 10.1128/JVI.00997-10  0.6
2010 Matthews QL, Fatima A, Tang Y, Perry BA, Tsuruta Y, Komarova S, Timares L, Zhao C, Makarova N, Borovjagin AV, Stewart PL, Wu H, Blackwell JL, Curiel DT. HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach. Plos One. 5: e11815. PMID 20676400 DOI: 10.1371/journal.pone.0011815  0.6
2010 Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, van den Tol MP, Hooijberg E, Pereboev A, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 706-15. PMID 20664356 DOI: 10.1097/CJI.0b013e3181eccbd4  0.36
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, ... ... Curiel DT, et al. MDA-7/IL-24 as a cancer therapeutic: from bench to bedside. Anti-Cancer Drugs. 21: 725-31. PMID 20613485 DOI: 10.1097/CAD.0b013e32833cfbe1  0.6
2010 Paupoo AAV, Zhu ZB, Wang M, Rein DT, Starzinski-Powitz A, Curiel DT. A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect Human Reproduction. 25: 2068-2083. PMID 20573677 DOI: 10.1093/humrep/deq137  0.6
2010 Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, Curiel DT, Grant S, Pellecchia M, Reed JC, Sarkar D, et al. Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine. Cancer Research. 70: 5034-45. PMID 20501829 DOI: 10.1158/0008-5472.CAN-10-0563  0.6
2010 Komarova S, Roth J, Alvarez R, Curiel DT, Pereboeva L. Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor. Journal of Ovarian Research. 3: 12. PMID 20500878 DOI: 10.1186/1757-2215-3-12  0.6
2010 Bhutia SK, Dash R, Das SK, Azab B, Su ZZ, Lee SG, Grant S, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24. Cancer Research. 70: 3667-76. PMID 20406981 DOI: 10.1158/0008-5472.CAN-09-3647  0.6
2010 Borovjagin AV, McNally LR, Wang M, Curiel DT, MacDougall MJ, Zinn KR. Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging. Molecular Imaging. 9: 59-75. PMID 20236604 DOI: 10.2310/7290.2010.00003  0.6
2010 Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P. Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1130-42. PMID 20179672 DOI: 10.1038/mt.2010.29  0.6
2010 Dash R, Dmitriev I, Su ZZ, Bhutia SK, Azab B, Vozhilla N, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells Cancer Gene Therapy. 17: 447-456. PMID 20150932 DOI: 10.1038/cgt.2009.91  0.6
2010 Hamed HA, Yacoub A, Park MA, Eulitt P, Sarkar D, Dimitrie IP, Chen CS, Grant S, Curiel DT, Fisher PB, Dent P. OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins. Cancer Biology & Therapy. 9: 526-36. PMID 20107314  0.6
2010 Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, Grant S, Curiel DT, Fisher PB, Dent P. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Research. 70: 1120-9. PMID 20103619 DOI: 10.1158/0008-5472.CAN-09-4043  0.6
2010 Li J, Fatima A, Komarova S, Ugai H, Uprety P, Roth JC, Wang M, Oster RA, Curiel DT, Matthews QL. Evaluation of adenovirus capsid labeling versus transgene expression. Virology Journal. 7: 21. PMID 20102632 DOI: 10.1186/1743-422X-7-21  0.6
2010 Yamamoto M, Curiel DT. Current issues and future directions of oncolytic adenoviruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 243-50. PMID 19935777 DOI: 10.1038/mt.2009.266  0.6
2010 Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells. Molecular Pharmacology. 77: 298-310. PMID 19910452 DOI: 10.1124/mol.109.061820  0.6
2010 Murakami M, Ugai H, Belousova N, Pereboev A, Dent P, Fisher PB, Everts M, Curiel DT. Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells. The Prostate. 70: 362-76. PMID 19902467 DOI: 10.1002/pros.21070  0.6
2010 Davydova J, Gavrikova T, Brown EJ, Luo X, Curiel DT, Vickers SM, Yamamoto M. In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy. Cancer Science. 101: 474-81. PMID 19900190 DOI: 10.1111/j.1349-7006.2009.01407.x  0.6
2010 Greco A, Di Benedetto A, Howard CM, Kelly S, Nande R, Dementieva Y, Miranda M, Brunetti A, Salvatore M, Claudio L, Sarkar D, Dent P, Curiel DT, Fisher PB, Claudio PP. Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 295-306. PMID 19888195 DOI: 10.1038/mt.2009.252  1
2010 Ugai H, Wang M, Le LP, Matthews DA, Yamamoto M, Curiel DT. In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection. Journal of Molecular Biology. 395: 55-78. PMID 19853616 DOI: 10.1016/j.jmb.2009.10.034  0.6
2010 Rein DT, Schmidt T, Bauerschmitz G, Hampl M, Beyer IM, Paupoo AA, Curiel DT, Breidenbach M. Treatment of endometriosis with a VEGF-targeted conditionally replicative adenovirus. Fertility and Sterility. 93: 2687-94. PMID 19524222 DOI: 10.1016/j.fertnstert.2009.04.042  1
2009 Uchino J, Takayama K, Harada A, Kawakami Y, Inoue H, Curiel DT, Nakanishi Y. [hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment]. Fukuoka Igaku Zasshi = Hukuoka Acta Medica. 100: 338-48. PMID 20391937  0.6
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors for transcriptional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5219. PMID 20147171 DOI: 10.1101/pdb.prot5219  1
2009 Kawakami Y, Curiel DT. Construction of fusion proteins for transductional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5218. PMID 20147170 DOI: 10.1101/pdb.prot5218  1
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors with RGD-modified fiber for transductional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5217. PMID 20147169 DOI: 10.1101/pdb.prot5217  1
2009 Tang Y, Wu H, Ugai H, Matthews QL, Curiel DT. Derivation of a triple mosaic adenovirus for cancer gene therapy. Plos One. 4: e8526. PMID 20046872 DOI: 10.1371/journal.pone.0008526  0.6
2009 Glasgow JN, Mikheeva G, Krasnykh V, Curiel DT. A strategy for adenovirus vector targeting with a secreted single chain antibody. Plos One. 4: e8355. PMID 20027223 DOI: 10.1371/journal.pone.0008355  0.6
2009 Dent P, Curiel DT, Grant S, Fisher PB. Minting a new class of polo-like-kinase inhibitors. Cancer Biology & Therapy. 8: 2384-5. PMID 20009506  0.6
2009 van de Ven R, Lindenberg JJ, Oosterhoff D, van den Tol MP, Rosalia RA, Murakami M, Everts M, Scheffer GL, Scheper RJ, de Gruijl TD, Curiel DT. Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 895-906. PMID 19816192 DOI: 10.1097/CJI.0b013e3181b56deb  0.32
2009 Kimball KJ, Rivera AA, Zinn KR, Icyuz M, Saini V, Li J, Zhu ZB, Siegal GP, Douglas JT, Curiel DT, Alvarez RD, Borovjagin AV. Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer. Molecular Imaging. 8: 264-77. PMID 19796604 DOI: 10.2310/7290.2009.00025  1
2009 Thacker EE, Nakayama M, Smith BF, Bird RC, Muminova Z, Strong TV, Timares L, Korokhov N, O'Neill AM, de Gruijl TD, Glasgow JN, Tani K, Curiel DT. A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo. Vaccine. 27: 7116-24. PMID 19786146 DOI: 10.1016/j.vaccine.2009.09.055  1
2009 Nelson AR, Davydova J, Curiel DT, Yamamoto M. Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer. Cancer Science. 100: 2181-7. PMID 19689475 DOI: 10.1111/j.1349-7006.2009.01289.x  0.6
2009 Short JJ, Curiel DT. Oncolytic adenoviruses targeted to cancer stem cells. Molecular Cancer Therapeutics. 8: 2096-102. PMID 19671759 DOI: 10.1158/1535-7163.MCT-09-0367  1
2009 Pérez-Berná AJ, Marabini R, Scheres SH, Menéndez-Conejero R, Dmitriev IP, Curiel DT, Mangel WF, Flint SJ, San Martín C. Structure and uncoating of immature adenovirus. Journal of Molecular Biology. 392: 547-57. PMID 19563809 DOI: 10.1016/j.jmb.2009.06.057  1
2009 Matthews K, Noker PE, Tian B, Grimes SD, Fulton R, Schweikart K, Harris R, Aurigemma R, Wang M, Barnes MN, Siegal GP, Hemminki A, Zinn K, Curiel DT, Alvarez RD. Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4131-7. PMID 19509153 DOI: 10.1158/1078-0432.CCR-08-3354  1
2009 Matthews KS, Alvarez RD, Curiel DT. Advancements in adenoviral based virotherapy for ovarian cancer. Advanced Drug Delivery Reviews. 61: 836-41. PMID 19422865 DOI: 10.1016/j.addr.2009.04.012  1
2009 Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, et al. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Molecular Cancer Therapeutics. 8: 1280-91. PMID 19417161 DOI: 10.1158/1535-7163.MCT-09-0073  1
2009 Dent P, Curiel DT, Fisher PB, Grant S. Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 12: 65-73. PMID 19395305 DOI: 10.1016/j.drup.2009.03.001  1
2009 Kashentseva EA, Douglas JT, Zinn KR, Curiel DT, Dmitriev IP. Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody. Journal of Molecular Biology. 388: 443-61. PMID 19285990 DOI: 10.1016/j.jmb.2009.03.016  1
2009 Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, Fisher PB. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biology & Therapy. 8: 391-400. PMID 19276652  1
2009 Haisma HJ, Boesjes M, Beerens AM, van der Strate BW, Curiel DT, Plüddemann A, Gordon S, Bellu AR. Scavenger receptor A: a new route for adenovirus 5. Molecular Pharmaceutics. 6: 366-74. PMID 19227971 DOI: 10.1021/mp8000974  1
2009 Li HJ, Everts M, Yamamoto M, Curiel DT, Herschman HR. Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors. Cancer Research. 69: 554-64. PMID 19147569 DOI: 10.1158/0008-5472.CAN-08-3209  1
2009 Dent P, Grant S, Fisher PB, Curiel DT. PI3K: A rational target for ovarian cancer therapy? Cancer Biology & Therapy. 8: 27-30. PMID 19127116  1
2009 Stoff A, Rivera AA, Banerjee NS, Moore ST, Numnum TM, Espinosa-de-los-Monteros A, Richter DF, Siegal GP, Chow LT, Feldman D, Vasconez LO, Mathis JM, Stoff-Khalili MA, Curiel DT. Promotion of incisional wound repair by human mesenchymal stem cell transplantation Experimental Dermatology. 18: 362-369. PMID 18803656 DOI: 10.1111/j.1600-0625.2008.00792.x  1
2009 Hedley SJ, Krendelshchikov A, Kim MH, Chen J, Hsu HC, Mountz JD, Curiel DT, Kovesdi I. Assessment of genetic shielding for adenovirus vectors Open Gene Therapy Journal. 2: 1-11. DOI: 10.2174/1875037000902010001  0.6
2008 Preuss MA, Glasgow JN, Everts M, Stoff-Khalili MA, Wu H, Curiel DT. Enhanced Gene Delivery to Human Primary Endothelial Cells Using Tropism-Modified Adenovirus Vectors. The Open Gene Therapy Journal. 1: 7-11. PMID 19834585 DOI: 10.2174/1875037000801010007  0.6
2008 Park MA, Zhang G, Mitchell C, Rahmani M, Hamed H, Hagan MP, Yacoub A, Curiel DT, Fisher PB, Grant S, Dent P. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95. Molecular Cancer Therapeutics. 7: 2633-48. PMID 18790746 DOI: 10.1158/1535-7163.MCT-08-0400  1
2008 San Martín C, Glasgow JN, Borovjagin A, Beatty MS, Kashentseva EA, Curiel DT, Marabini R, Dmitriev IP. Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid. Journal of Molecular Biology. 383: 923-34. PMID 18786542 DOI: 10.1016/j.jmb.2008.08.054  1
2008 Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5385-99. PMID 18765530 DOI: 10.1158/1078-0432.CCR-08-0469  1
2008 Paul CP, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CM, Lamfers ML, Siegal GP, Zhu ZB, Curiel DT. Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biology & Therapy. 7: 786-93. PMID 18756624 DOI: 10.4161/cbt.7.5.5421  1
2008 Matthews QL, Yang P, Wu Q, Belousova N, Rivera AA, Stoff-Khalili MA, Waehler R, Hsu HC, Li Z, Li J, Mountz JD, Wu H, Curiel DT. Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach. Virology Journal. 5: 98. PMID 18718011 DOI: 10.1186/1743-422X-5-98  1
2008 Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB. Searching for a cure: gene therapy for glioblastoma. Cancer Biology & Therapy. 7: 1335-40. PMID 18708757  1
2008 Othman EE, Zhu ZB, Curiel DT, Khatoon N, Salem HT, Khalifa EA, Al-Hendy A. Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. American Journal of Obstetrics and Gynecology. 199: 117.e1-6. PMID 18674655 DOI: 10.1016/j.ajog.2008.01.059  1
2008 van de Ven R, Scheffer GL, Reurs AW, Lindenberg JJ, Oerlemans R, Jansen G, Gillet JP, Glasgow JN, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration. Blood. 112: 2353-9. PMID 18625884 DOI: 10.1182/blood-2008-03-147850  1
2008 Tang Y, Le LP, Matthews QL, Han T, Wu H, Curiel DT. Derivation of a triple mosaic adenovirus based on modification of the minor capsid protein IX. Virology. 377: 391-400. PMID 18570971 DOI: 10.1016/j.virol.2008.04.023  1
2008 Chen J, Wang J, Li J, Wu Q, Chu Lim F, Yang P, Hsu HC, Curiel DT, Mountz JD. Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1500-6. PMID 18545221 DOI: 10.1038/mt.2008.121  1
2008 Sekine S, Kataoka K, Fukuyama Y, Adachi Y, Davydova J, Yamamoto M, Kobayashi R, Fujihashi K, Suzuki H, Curiel DT, Shizukuishi S, McGhee JR, Fujihashi K. A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 8126-34. PMID 18523277  1
2008 Tsuruta Y, Pereboeva L, Breidenbach M, Rein DT, Wang M, Alvarez RD, Siegal GP, Dent P, Fisher PB, Curiel DT. A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3582-8. PMID 18519792 DOI: 10.1158/1078-0432.CCR-07-5053  1
2008 Zhu ZB, Lu B, Park M, Makhija SK, Numnum TM, Kendrick JE, Wang M, Tsuruta Y, Fisher P, Alvarez RD, Zhou F, Siegal GP, Wu H, Curiel DT. Development of an optimized conditionally replicative adenoviral agent for ovarian cancer. International Journal of Oncology. 32: 1179-88. PMID 18497979 DOI: 10.3892/ijo_32_6_1179  1
2008 Wu H, Curiel DT. Fiber-modified adenoviruses for targeted gene therapy. Methods in Molecular Biology (Clifton, N.J.). 434: 113-32. PMID 18470642 DOI: 10.1007/978-1-60327-248-3_8  1
2008 Bird RC, Deinnocentes P, Lenz S, Thacker EE, Curiel DT, Smith BF. An allogeneic hybrid-cell fusion vaccine against canine mammary cancer. Veterinary Immunology and Immunopathology. 123: 289-304. PMID 18423623 DOI: 10.1016/j.vetimm.2008.02.013  1
2008 Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus WC, Ramakrishnan V, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB, Dent P. MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biology & Therapy. 7: 917-33. PMID 18376144 DOI: 10.4161/cbt.7.6.5928  1
2008 Roth JC, Curiel DT, Pereboeva L. Cell vehicle targeting strategies Gene Therapy. 15: 716-729. PMID 18369326 DOI: 10.1038/gt.2008.38  1
2008 Ramírez PJ, Vickers SM, Ono HA, Davydova J, Takayama K, Thompson TC, Curiel DT, Bland KI, Yamamoto M. Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model American Journal of Surgery. 195: 481-490. PMID 18361926 DOI: 10.1016/j.amjsurg.2007.04.014  1
2008 Sarkar D, Su ZZ, Park ES, Vozhilla N, Dent P, Curiel DT, Fisher PB. A cancer terminator virus eradicates both primary and distant human melanomas. Cancer Gene Therapy. 15: 293-302. PMID 18323853 DOI: 10.1038/cgt.2008.14  1
2008 Park MA, Yacoub A, Sarkar D, Emdad L, Rahmani M, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P. PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells. Autophagy. 4: 513-5. PMID 18299661  1
2008 Yacoub A, Gupta P, Park MA, Rhamani M, Hamed H, Hanna D, Zhang G, Sarkar D, Lebedeva IV, Emdad L, Koumenis C, Curiel DT, Grant S, Fisher PB, Dent P. Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling Molecular Cancer Therapeutics. 7: 314-329. PMID 18281516 DOI: 10.1158/1535-7163.MCT-07-2150  1
2008 Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, ... Curiel DT, et al. Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells. Molecular Cancer Therapeutics. 7: 297-313. PMID 18281515 DOI: 10.1158/1535-7163.MCT-07-2166  1
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: Not insurmountable therapeutic problems Cancer Biology and Therapy. 7: 109-112. PMID 18277093  1
2008 Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, Fisher PB. Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva. Journal of Cellular Physiology. 215: 827-36. PMID 18270968 DOI: 10.1002/jcp.21369  1
2008 Park MA, Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P. PERK-dependent regulation of HSP70 expression and the regulation of autophagy. Autophagy. 4: 364-7. PMID 18216498  1
2008 Schoehn G, El Bakkouri ME, Fabry CMS, Billet O, Estrozi LF, Le L, Curiel DT, Kajava AV, Ruigrok RWH, Kremer EJ. Three-dimensional structure of canine adenovirus serotype 2 capsid Journal of Virology. 82: 3192-3203. PMID 18216088 DOI: 10.1128/JVI.02393-07  1
2008 Saini V, Martyshkin DV, Mirov SB, Perez A, Perkins G, Ellisman MH, Towner VD, Wu H, Pereboeva L, Borovjagin A, Curiel DT, Everts M. An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 4: 262-9. PMID 18200644 DOI: 10.1002/smll.200700403  1
2008 Hassan MH, Khatoon N, Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells. Human Reproduction (Oxford, England). 23: 514-24. PMID 18184643 DOI: 10.1093/humrep/dem410  1
2008 Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, et al. OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Molecular Pharmacology. 73: 1168-84. PMID 18182481 DOI: 10.1124/mol.107.042697  1
2008 Uchino J, Takayama K, Harada A, Sone T, Harada T, Curiel DT, Kuroki M, Nakanishi Y. Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan Cancer Gene Therapy. 15: 94-100. PMID 18157147 DOI: 10.1038/sj.cgt.7701100  1
2008 Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ. Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy Expert Opinion On Drug Delivery. 5: 87-103. PMID 18095930 DOI: 10.1517/17425247.5.1.87  1
2008 Numnum TM, Makhija S, Lu B, Wang M, Rivera A, Stoff-Khalili M, Alvarez RD, Zhu ZB, Curiel DT. Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines. Gynecologic Oncology. 108: 34-41. PMID 18061250 DOI: 10.1016/j.ygyno.2007.08.096  1
2008 Huang D, Pereboev AV, Korokhov N, He R, Larocque L, Gravel C, Jaentschke B, Tocchi M, Casley WL, Lemieux M, Curiel DT, Chen W, Li X. Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells. Gene Therapy. 15: 298-308. PMID 18046426 DOI: 10.1038/sj.gt.3303085  1
2008 Schierer S, Hesse A, Müller I, Kämpgen E, Curiel DT, Schuler G, Steinkasserer A, Nettelbeck DM. Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses International Journal of Cancer. 122: 219-229. PMID 17764070 DOI: 10.1002/ijc.23074  1
2008 Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, DeBenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Research and Treatment. 108: 43-55. PMID 17508279 DOI: 10.1007/s10549-007-9587-7  1
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. INGN-241: Cancer gene therapy Drugs of the Future. 33: 396-401. DOI: 10.1358/dof.2008.033.05.1201624  1
2008 Paul CPL, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CMF, Lamfers MLM, Siegal GP, Zhu ZB, Curiel DT. Characterization of infectivity of knob-modified adenoviral vectors in glioma Cancer Biology and Therapy. 7: 788-795.  1
2007 Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P. Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells. Molecular Cancer Therapeutics. 6: 3101-12. PMID 18065490 DOI: 10.1158/1535-7163.MCT-07-0561  1
2007 Emdad L, Lebedeva IV, Su ZZ, Sarkar D, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells. Molecular Cancer Therapeutics. 6: 2985-94. PMID 18025283 DOI: 10.1158/1535-7163.MCT-07-0399  1
2007 Zhu ZB, Mathis JM, Makhija SK, Lu B, Wang M, Ji S, Rivera AA, Rosenthal EL, Siegal GP, Curiel DT. Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck. International Journal of Oncology. 31: 1213-22. PMID 17912450  0.6
2007 Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, ... ... Curiel DT, et al. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). International Journal of Oncology. 31: 985-1007. PMID 17912425  0.6
2007 Ulasov IV, Rivera AA, Han Y, Curiel DT, Zhu ZB, Lesniak MS. Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells Journal of Neurosurgery. 107: 617-627. PMID 17886563 DOI: 10.3171/JNS-07/09/0617  1
2007 Miura Y, Yoshida K, Nishimoto T, Hatanaka K, Ohnami S, Asaka M, Douglas JT, Curiel DT, Yoshida T, Aoki K. Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob. Gene Therapy. 14: 1448-60. PMID 17700705 DOI: 10.1038/sj.gt.3303007  1
2007 Gaballah K, Hills A, Curiel D, Hallden G, Harrison P, Partridge M. Lysis of dysplastic but not normal oral keratinocytes and tissue-engineered epithelia with conditionally replicating adenoviruses Cancer Research. 67: 7284-7294. PMID 17671197 DOI: 10.1158/0008-5472.CAN-06-3834  1
2007 Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS. Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma Human Gene Therapy. 18: 589-602. PMID 17630837 DOI: 10.1089/hum.2007.002  1
2007 Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy Nature Reviews Genetics. 8: 573-587. PMID 17607305 DOI: 10.1038/nrg2141  1
2007 Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P. Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling. Molecular Pharmacology. 72: 704-14. PMID 17578896 DOI: 10.1124/mol.107.038406  1
2007 Sarkar D, Lebedeva IV, Su ZZ, Park ES, Chatman L, Vozhilla N, Dent P, Curiel DT, Fisher PB. Eradication of therapy-resistant human prostate tumors using a cancer terminator virus. Cancer Research. 67: 5434-42. PMID 17545625 DOI: 10.1158/0008-5472.CAN-07-0195  1
2007 Li HJ, Everts M, Pereboeva L, Komarova S, Idan A, Curiel DT, Herschman HR. Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer Research. 67: 5354-61. PMID 17545616 DOI: 10.1158/0008-5472.CAN-06-4679  1
2007 Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS. Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models. Neuro-Oncology. 9: 280-90. PMID 17522331 DOI: 10.1215/15228517-2007-017  1
2007 Sarkar D, Lebedeva IV, Gupta P, Emdad L, Sauane M, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7 (mda-7)/IL-24: A 'magic bullet' for cancer therapy? Expert Opinion On Biological Therapy. 7: 577-586. PMID 17477796 DOI: 10.1517/14712598.7.5.577  1
2007 Tsuruta Y, Pereboeva L, Glasgow JN, Rein DT, Kawakami Y, Alvarez RD, Rocconi RP, Siegal GP, Dent P, Fisher PB, Curiel DT. A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2777-83. PMID 17473211 DOI: 10.1158/1078-0432.CCR-06-2706  1
2007 Page JG, Tian B, Schweikart K, Tomaszewski J, Harris R, Broadt T, Polley-Nelson J, Noker PE, Wang M, Makhija S, Aurigemma R, Curiel DT, Alvarez RD. Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer. American Journal of Obstetrics and Gynecology. 196: 389.e1-9; discussion. PMID 17403430 DOI: 10.1016/j.ajog.2006.12.016  1
2007 Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Radiation-induced cell signaling: inside-out and outside-in. Molecular Cancer Therapeutics. 6: 789-801. PMID 17363476 DOI: 10.1158/1535-7163.MCT-06-0596  1
2007 Lebedeva IV, Washington I, Sarkar D, Clark JA, Fine RL, Dent P, Curiel DT, Turro NJ, Fisher PB. Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 3484-9. PMID 17360670 DOI: 10.1073/pnas.0700042104  1
2007 Yoshio-Hoshino N, Adachi Y, Aoki C, Pereboev A, Curiel DT, Nishimoto N. Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor. Cancer Research. 67: 871-5. PMID 17283116 DOI: 10.1158/0008-5472.CAN-06-3641  1
2007 Reynolds AM, Xia W, Holmes MD, Hodge SJ, Danilov S, Curiel DT, Morrell NW, Reynolds PN. Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1182-92. PMID 17277049 DOI: 10.1152/ajplung.00020.2006  1
2007 Preuss MA, Curiel DT. Gene therapy: science fiction or reality? Southern Medical Journal. 100: 101-4. PMID 17269545 DOI: 10.1097/SMJ.0b013e31802e65dd  1
2007 Matthews QL, Curiel DT. Gene therapy: Human germline genetic modifications - Assessing the scientific, socioethical, and religious issues Southern Medical Journal. 100: 98-100. PMID 17269544 DOI: 10.1097/SMJ.0b013e31802e645f  1
2007 Pereboeva L, Komarova S, Roth J, Ponnazhagan S, Curiel DT. Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus Gene Therapy. 14: 627-637. PMID 17251987 DOI: 10.1038/sj.gt.3302916  1
2007 Lam JT, Hemminki A, Kanerva A, Lee KB, Blackwell JL, Desmond R, Siegal GP, Curiel DT. A three-dimensional assay for measurement of viral-induced oncolysis Cancer Gene Therapy. 14: 421-430. PMID 17235353 DOI: 10.1038/sj.cgt.7701028  1
2007 Perreau M, Mennechet F, Serratrice N, Glasgow JN, Curiel DT, Wodrich H, Kremer EJ. Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. Journal of Virology. 81: 3272-84. PMID 17229706 DOI: 10.1128/JVI.01530-06  1
2007 Stoff-Khalili MA, Rivera AA, Mathis JM, Banerjee NS, Moon AS, Hess A, Rocconi RP, Numnum TM, Everts M, Chow LT, Douglas JT, Siegal GP, Zhu ZB, Bender HG, Dall P, ... ... Curiel DT, et al. Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma. Breast Cancer Research and Treatment. 105: 157-67. PMID 17221158 DOI: 10.1007/s10549-006-9449-8  1
2007 Stoff A, Rivera AA, Mathis JM, Moore ST, Banerjee NS, Everts M, Espinosa-de-los-Monteros A, Novak Z, Vasconez LO, Broker TR, Richter DF, Feldman D, Siegal GP, Stoff-Khalili MA, Curiel DT. Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds. Journal of Molecular Medicine (Berlin, Germany). 85: 481-96. PMID 17219096 DOI: 10.1007/s00109-006-0148-z  1
2007 Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M, Su ZZ, Grant S, Dent P, Curiel DT, Senzer N, Nemunaitis J. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma. Toxicology and Applied Pharmacology. 224: 300-7. PMID 17208263 DOI: 10.1016/j.taap.2006.11.021  1
2007 Ugai H, Borovjagin AV, Le LP, Wang M, Curiel DT. Thermostability/Infectivity Defect Caused by Deletion of the Core Protein V Gene in Human Adenovirus Type 5 Is Rescued by Thermo-selectable Mutations in the Core Protein X Precursor Journal of Molecular Biology. 366: 1142-1160. PMID 17208253 DOI: 10.1016/j.jmb.2006.11.090  1
2007 Witlox MA, Lamfers ML, Wuisman PIJM, Curiel DT, Siegal GP. Evolving gene therapy approaches for osteosarcoma using viral vectors: Review Bone. 40: 797-812. PMID 17189720 DOI: 10.1016/j.bone.2006.10.017  1
2007 Rocconi RP, Zhu ZB, Stoff-Khalili M, Rivera AA, Lu B, Wang M, Alvarez RD, Curiel DT, Makhija SK. Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd) Gynecologic Oncology. 105: 113-121. PMID 17173958 DOI: 10.1016/j.ygyno.2006.10.057  1
2007 Tang Y, Han T, Everts M, Zhu ZB, Gillespie GY, Curiel DT, Wu H. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Therapy. 14: 523-32. PMID 17167498 DOI: 10.1038/sj.gt.3302888  1
2007 Stoff-Khalili MA, Rivera AA, Stoff A, Mathis JM, Rocconi RP, Matthews QL, Numnum MT, Herrmann I, Dall P, Eckhoff DE, Douglas JT, Siegal GP, Zhu ZB, Curiel DT. Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer International Journal of Cancer. 120: 935-941. PMID 17131341 DOI: 10.1002/ijc.22338  1
2007 Zhu ZB, Rivera AA, Makhija SK, Lu B, Wang M, Izumi M, Cerfolio RJ, Stoff-Khalili MA, Zhou F, Takayama K, Siegal GP, Curiel DT. Targeting lung cancer using an infectivity enhanced CXCR4-CRAd Lung Cancer. 55: 145-156. PMID 17113184 DOI: 10.1016/j.lungcan.2006.10.012  1
2007 Yacoub A, Hawkins W, Hanna D, Young H, Park MA, Grant M, Roberts JD, Curiel DT, Fisher PB, Valerie K, Grant S, Hagan MP, Dent P. Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment. Molecular Pharmacology. 71: 259-75. PMID 17050804 DOI: 10.1124/mol.106.031153  1
2007 Takayama K, Reynolds PN, Adachi Y, Kaliberova L, Uchino J, Nakanishi Y, Curiel DT. Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application Cancer Gene Therapy. 14: 105-116. PMID 17024232 DOI: 10.1038/sj.cgt.7700991  1
2007 Jung JS, Stoff A, Rivera AA, Mathis JM, Hess A, Rein D, Fleisch MC, Dall P, Curiel DT, Niederacher D, Bender HG, Stoff-Khalili MA. Stem cells as cellular vehicles for virotherapeutic agents in metastatic breast cancer | Stammzellen als zelluläre vehikel virotherapeutischer agenzien beim metastasierten mammakarzinom Geburtshilfe Und Frauenheilkunde. 67: 236-241. DOI: 10.1055/s-2007-965053  1
2007 Passineau MJ, Curiel DT. Gene transfer and expression in the vascular endothelium Endothelial Biomedicine. 1725-1733. DOI: 10.1017/CBO9780511546198.186  0.6
2007 Matthews QL, Curiel DT. Vector Targeting Concepts in Genetic Medicine. 223-228. DOI: 10.1002/9780470184585.ch18  1
2006 Gommans WM, Oosterhuis D, Dmitriev I, Schaack J, Curiel DT, Haisma HJ, Rots MG. Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill. Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: e64-6. PMID 17718975 DOI: 10.1016/j.jconrel.2006.09.052  1
2006 Smith BF, Curiel DT, Ternovoi VV, Borovjagin AV, Baker HJ, Cox N, Siegal GP. Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs. Cancer Biotherapy & Radiopharmaceuticals. 21: 601-6. PMID 17257075 DOI: 10.1089/cbr.2006.21.601  1
2006 Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, Aird WC. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. The Journal of Biological Chemistry. 281: 35544-53. PMID 16980307 DOI: 10.1074/jbc.M608620200  1
2006 Short JJ, Vasu C, Holterman MJ, Curiel DT, Pereboev A. Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors. Virus Research. 122: 144-53. PMID 16920215 DOI: 10.1016/j.virusres.2006.07.009  1
2006 Belousova N, Harris R, Zinn K, Rhodes-Selser MA, Kotov A, Kotova O, Wang M, Aurigemma R, Zhu ZB, Curiel DT, Alvarez RD. Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette. Molecular Pharmacology. 70: 1488-93. PMID 16896072 DOI: 10.1124/mol.106.025619  1
2006 Rocconi RP, Numnum MT, Zhu ZB, Lu B, Wang M, Rivera AA, Stoff-Khalili M, Alvarez RD, Curiel DT, Makhija S. Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy Gynecologic Oncology. 103: 985-989. PMID 16857247 DOI: 10.1016/j.ygyno.2006.06.005  1
2006 Everts M, Saini V, Leddon JL, Kok RJ, Stoff-Khalili M, Preuss MA, Millican CL, Perkins G, Brown JM, Bagaria H, Nikles DE, Johnson DT, Zharov VP, Curiel DT. Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Letters. 6: 587-91. PMID 16608249 DOI: 10.1021/nl0500555  1
2005 Ono HA, Davydova JG, Adachi Y, Takayama K, Barker SD, Reynolds PN, Krasnykh VN, Kunisaki C, Shimada H, Curiel DT, Yamamoto M. Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer. Journal of Gastroenterology. 40: 31-42. PMID 15692787 DOI: 10.1007/s00535-004-1490-y  1
2004 Short JJ, Pereboev AV, Kawakami Y, Vasu C, Holterman MJ, Curiel DT. Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors. Virology. 322: 349-59. PMID 15110532 DOI: 10.1016/j.virol.2004.02.016  1
2004 Timares L, Douglas JT, Tillman BW, Krasnykh V, Curiel DT. Adenovirus-mediated gene delivery to dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 246: 139-54. PMID 14970589  1
2003 Stam AG, Santegoets SJ, Westers TM, Sombroek CC, Janssen JJ, Tillman BW, van de Loosdrecht AA, Pinedo HM, Curiel DT, Ossenkoppele GJ, Scheper RJ, de Gruijl TD. CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation. British Journal of Cancer. 89: 1162-5. PMID 14520439 DOI: 10.1038/sj.bjc.6601225  1
2003 Barker SD, Dmitriev IP, Nettelbeck DM, Liu B, Rivera AA, Alvarez RD, Curiel DT, Hemminki A. Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma. Gene Therapy. 10: 1198-204. PMID 12833129 DOI: 10.1038/sj.gt.3301974  1
2003 Takayama K, Reynolds PN, Short JJ, Kawakami Y, Adachi Y, Glasgow JN, Rots MG, Krasnykh V, Douglas JT, Curiel DT. A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism. Virology. 309: 282-93. PMID 12758175 DOI: 10.1016/S0042-6822(03)00067-9  1
2003 Brandão JG, Scheper RJ, Lougheed SM, Curiel DT, Tillman BW, Gerritsen WR, van den Eertwegh AJ, Pinedo HM, Haisma HJ, de Gruijl TD. CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation. Vaccine. 21: 2268-72. PMID 12744857 DOI: 10.1016/S0264-410X(03)00050-1  1
2003 Lam JT, Bauerschmitz GJ, Kanerva A, Barker SD, Straughn JM, Wang M, Barnes MN, Blackwell JL, Siegal GP, Alvarez RD, Curiel DT, Hemminki A. Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids. Cancer Gene Therapy. 10: 377-87. PMID 12719707 DOI: 10.1038/sj.cgt.7700578  1
2003 Barker SD, Coolidge CJ, Kanerva A, Hakkarainen T, Yamamoto M, Liu B, Rivera AA, Bhoola SM, Barnes MN, Alvarez RD, Curiel DT, Hemminki A. The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy. The Journal of Gene Medicine. 5: 300-10. PMID 12692864 DOI: 10.1002/jgm.341  1
2003 Hakkarainen T, Hemminki A, Pereboev AV, Barker SD, Asiedu CK, Strong TV, Kanerva A, Wahlfors J, Curiel DT. CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 619-24. PMID 12576427  1
2002 de Gruijl TD, Luykx-de Bakker SA, Tillman BW, van den Eertwegh AJ, Buter J, Lougheed SM, van der Bij GJ, Safer AM, Haisma HJ, Curiel DT, Scheper RJ, Pinedo HM, Gerritsen WR. Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors. Journal of Immunology (Baltimore, Md. : 1950). 169: 5322-31. PMID 12391253  1
2002 Barnett BG, Tillman BW, Curiel DT, Douglas JT. Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 377-85. PMID 12231174 DOI: 10.1006/mthe.2002.0670  1
2002 Arafat WO, Gómez-Navarro J, Buchsbaum DJ, Xiang J, Wang M, Casado E, Barker SD, Mahasreshti PJ, Haisma HJ, Barnes MN, Siegal GP, Alvarez RD, Hemminki A, Nettelbeck DM, Curiel DT. Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv. Gene Therapy. 9: 256-62. PMID 11896464 DOI: 10.1038/sj.gt.3301639  1
2002 Kanerva A, Mikheeva GV, Krasnykh V, Coolidge CJ, Lam JT, Mahasreshti PJ, Barker SD, Straughn M, Barnes MN, Alvarez RD, Hemminki A, Curiel DT. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 275-80. PMID 11801569  1
2001 Casado E, Gomez-Navarro J, Yamamoto M, Adachi Y, Coolidge CJ, Arafat WO, Barker SD, Wang MH, Mahasreshti PJ, Hemminki A, Gonzalez-Baron M, Barnes MN, Pustilnik TB, Siegal GP, Alvarez RD, ... Curiel DT, et al. Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 2496-504. PMID 11489832  1
2001 Barker SD, Casado E, Gomez-Navarro J, Xiang J, Arafat W, Mahasreshti P, Pustilnik TB, Hemminki A, Siegal GP, Alvarez RD, Curiel DT. An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites. Gynecologic Oncology. 82: 57-63. PMID 11426962 DOI: 10.1006/gyno.2001.6226  1
2000 Tillman BW, Hayes TL, DeGruijl TD, Douglas JT, Curiel DT. Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model. Cancer Research. 60: 5456-63. PMID 11034088  1
2000 Xiang J, Gómez-Navarro J, Arafat W, Liu B, Barker SD, Alvarez RD, Siegal GP, Curiel DT. Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer. The Journal of Gene Medicine. 2: 97-106. PMID 10809143 DOI: 10.1002/(SICI)1521-2254(200003/04)2:2<97::AID-JGM99>3.0.CO;2-S  1
1999 Haisma HJ, Pinedo HM, Rijswijk A, der Meulen-Muileman I, Sosnowski BA, Ying W, Beusechem VW, Tillman BW, Gerritsen WR, Curiel DT. Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM. Gene Therapy. 6: 1469-74. PMID 10467371 DOI: 10.1038/sj.gt.3300969  1
1999 Tillman BW, de Gruijl TD, Luykx-de Bakker SA, Scheper RJ, Pinedo HM, Curiel TJ, Gerritsen WR, Curiel DT. Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector. Journal of Immunology (Baltimore, Md. : 1950). 162: 6378-83. PMID 10352250  1
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