Year |
Citation |
Score |
2020 |
Parmar M, Grealish S, Henchcliffe C. The future of stem cell therapies for Parkinson disease. Nature Reviews. Neuroscience. PMID 31907406 DOI: 10.1038/S41583-019-0257-7 |
0.694 |
|
2019 |
Adler AF, Cardoso T, Nolbrant S, Mattsson B, Hoban DB, Jarl U, Wahlestedt JN, Grealish S, Björklund A, Parmar M. hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease. Cell Reports. 28: 3462-3473.e5. PMID 31553914 DOI: 10.1016/J.Celrep.2019.08.058 |
0.768 |
|
2018 |
Cardoso T, Adler A, Mattsson B, Hoban DB, Nolbrant S, Nelander Wahlestedt J, Kirkeby A, Grealish S, Björklund A, Parmar M. Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats. The Journal of Comparative Neurology. PMID 30007046 DOI: 10.1002/Cne.24500 |
0.735 |
|
2017 |
Lehnen D, Barral S, Cardoso T, Grealish S, Heuer A, Smiyakin A, Kirkeby A, Kollet J, Cremer H, Parmar M, Bosio A, Knöbel S. IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 28943253 DOI: 10.1016/J.Stemcr.2017.08.016 |
0.729 |
|
2017 |
Tornero D, Tsupykov O, Granmo M, Rodriguez C, Grønning-Hansen M, Thelin J, Smozhanik E, Laterza C, Wattananit S, Ge R, Tatarishvili J, Grealish S, Brüstle O, Skibo G, Parmar M, et al. Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli. Brain : a Journal of Neurology. PMID 28115364 DOI: 10.1093/Brain/Aww347 |
0.777 |
|
2017 |
Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease. Cell Stem Cell. 20: 135-148. PMID 28094017 DOI: 10.1016/J.Stem.2016.09.004 |
0.729 |
|
2017 |
Grealish S, Drouin-Ouellet J, Parmar M. Brain repair and reprogramming: the route to clinical translation. Journal of Internal Medicine. 280: 265-75. PMID 27539906 DOI: 10.1111/Joim.12475 |
0.693 |
|
2016 |
Grealish S, Parmar M. Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair. Cell Stem Cell. 19: 679-680. PMID 27912087 DOI: 10.1016/J.Stem.2016.11.008 |
0.628 |
|
2015 |
Torper O, Ottosson DR, Pereira M, Lau S, Cardoso T, Grealish S, Parmar M. In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry. Cell Reports. 12: 474-81. PMID 26166567 DOI: 10.1016/J.Celrep.2015.06.040 |
0.716 |
|
2015 |
Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M. Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons. Stem Cell Reports. 4: 975-83. PMID 26004633 DOI: 10.1016/J.Stemcr.2015.04.011 |
0.794 |
|
2015 |
Kopra J, Vilenius C, Grealish S, Härma MA, Varendi K, Lindholm J, Castrén E, Võikar V, Björklund A, Piepponen TP, Saarma M, Andressoo JO. GDNF is not required for catecholaminergic neuron survival in vivo. Nature Neuroscience. 18: 319-22. PMID 25710828 DOI: 10.1038/Nn.3941 |
0.621 |
|
2014 |
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. Cell Stem Cell. 15: 653-65. PMID 25517469 DOI: 10.1016/J.Stem.2014.09.017 |
0.762 |
|
2014 |
Pereira M, Pfisterer U, Rylander D, Torper O, Lau S, Lundblad M, Grealish S, Parmar M. Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain. Scientific Reports. 4: 6330. PMID 25208484 DOI: 10.1038/Srep06330 |
0.713 |
|
2013 |
Nelander J, Grealish S, Parmar M. Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases. Neuroreport. 24: 1025-30. PMID 24257249 DOI: 10.1097/Wnr.0000000000000058 |
0.684 |
|
2013 |
Rylander D, Bagetta V, Pendolino V, Zianni E, Grealish S, Gardoni F, Di Luca M, Calabresi P, Cenci MA, Picconi B. Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 110: E4375-84. PMID 24170862 DOI: 10.1073/Pnas.1311187110 |
0.549 |
|
2013 |
Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M. Generation of induced neurons via direct conversion in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 7038-43. PMID 23530235 DOI: 10.1073/Pnas.1303829110 |
0.773 |
|
2012 |
Kirkeby A, Grealish S, Wolf DA, Nelander J, Wood J, Lundblad M, Lindvall O, Parmar M. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Reports. 1: 703-14. PMID 22813745 DOI: 10.1016/J.Celrep.2012.04.009 |
0.796 |
|
2011 |
Grealish S, Jakobsson J, Parmar M. Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3421-2. PMID 22067653 DOI: 10.4161/Cc.10.20.17691 |
0.764 |
|
2010 |
Grealish S, Mattsson B, Draxler P, Björklund A. Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease. The European Journal of Neuroscience. 31: 2266-78. PMID 20529122 DOI: 10.1111/J.1460-9568.2010.07265.X |
0.416 |
|
2010 |
Grealish S, Jönsson ME, Li M, Kirik D, Björklund A, Thompson LH. The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease. Brain : a Journal of Neurology. 133: 482-95. PMID 20123725 DOI: 10.1093/Brain/Awp328 |
0.767 |
|
2009 |
Thompson LH, Grealish S, Kirik D, Björklund A. Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain. The European Journal of Neuroscience. 30: 625-38. PMID 19674082 DOI: 10.1111/J.1460-9568.2009.06878.X |
0.749 |
|
2008 |
Grealish S, Xie L, Kelly M, Dowd E. Unilateral axonal or terminal injection of 6-hydroxydopamine causes rapid-onset nigrostriatal degeneration and contralateral motor impairments in the rat. Brain Research Bulletin. 77: 312-9. PMID 18817852 DOI: 10.1016/J.Brainresbull.2008.08.018 |
0.314 |
|
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