Paul A. Heppenstall - Publications

Affiliations: 
EMBL, Montorotondo Outstation, Rome, Monterotondo, Lazio, Italy 
Area:
Ion channels, pain, neurotrophins

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Taberner FJ, Prato V, Schaefer I, Schrenk-Siemens K, Heppenstall PA, Lechner SG. Structure-guided examination of the mechanogating mechanism of PIEZO2. Proceedings of the National Academy of Sciences of the United States of America. PMID 31235572 DOI: 10.1073/pnas.1905985116  0.6
2019 Nocchi L, Roy N, D'Attilia M, Dhandapani R, Maffei M, Traista A, Castaldi L, Perlas E, Chadick CH, Heppenstall PA. Interleukin-31-mediated photoablation of pruritogenic epidermal neurons reduces itch-associated behaviours in mice. Nature Biomedical Engineering. 3: 114-125. PMID 30944432 DOI: 10.1038/s41551-018-0328-5  0.52
2018 Dhandapani R, Arokiaraj CM, Taberner FJ, Pacifico P, Raja S, Nocchi L, Portulano C, Franciosa F, Maffei M, Hussain AF, de Castro Reis F, Reymond L, Perlas E, Garcovich S, Barth S, ... ... Heppenstall PA, et al. Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nature Communications. 9: 1640. PMID 29691410 DOI: 10.1038/s41467-018-04049-3  0.6
2017 Prato V, Taberner FJ, Hockley JRF, Callejo G, Arcourt A, Tazir B, Hammer L, Schad P, Heppenstall PA, Smith ES, Lechner SG. Functional and Molecular Characterization of Mechanoinsensitive "Silent" Nociceptors. Cell Reports. 21: 3102-3115. PMID 29241539 DOI: 10.1016/j.celrep.2017.11.066  0.6
2016 Arcourt A, Gorham L, Dhandapani R, Prato V, Taberner FJ, Wende H, Gangadharan V, Birchmeier C, Heppenstall PA, Lechner SG. Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination. Neuron. PMID 27989460 DOI: 10.1016/j.neuron.2016.11.027  0.6
2016 Stantcheva KK, Iovino L, Dhandapani R, Martinez C, Castaldi L, Nocchi L, Perlas E, Portulano C, Pesaresi M, Shirlekar KS, de Castro Reis F, Paparountas T, Bilbao D, Heppenstall PA. A subpopulation of itch-sensing neurons marked by Ret and somatostatin expression. Embo Reports. PMID 26929027 DOI: 10.15252/embr.201540983  0.96
2015 Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stösser S, Srivastava K, Schweizerhof M, Waltenberger J, Ferrara N, Heppenstall P, Shibuya M, Augustin HG, Kuner R. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 27: 780-96. PMID 26058077 DOI: 10.1016/j.ccell.2015.04.017  0.96
2015 Reinhold AK, Batti L, Bilbao D, Buness A, Rittner HL, Heppenstall PA. Differential transcriptional profiling of damaged and intact adjacent dorsal root ganglia neurons in neuropathic pain. Plos One. 10: e0123342. PMID 25880204 DOI: 10.1371/journal.pone.0123342  0.96
2015 Yang G, de Castro Reis F, Sundukova M, Pimpinella S, Asaro A, Castaldi L, Batti L, Bilbao D, Reymond L, Johnsson K, Heppenstall PA. Genetic targeting of chemical indicators in vivo. Nature Methods. 12: 137-9. PMID 25486061 DOI: 10.1038/nmeth.3207  0.96
2014 Chen JT, Guo D, Campanelli D, Frattini F, Mayer F, Zhou L, Kuner R, Heppenstall PA, Knipper M, Hu J. Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction. Nature Communications. 5: 5331. PMID 25354791 DOI: 10.1038/ncomms6331  0.96
2014 Simonetti M, Agarwal N, Stösser S, Bali KK, Karaulanov E, Kamble R, Pospisilova B, Kurejova M, Birchmeier W, Niehrs C, Heppenstall P, Kuner R. Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways. Neuron. 83: 104-21. PMID 24991956 DOI: 10.1016/j.neuron.2014.05.037  0.96
2013 Kress M, Hüttenhofer A, Landry M, Kuner R, Favereaux A, Greenberg D, Bednarik J, Heppenstall P, Kronenberg F, Malcangio M, Rittner H, Uçeyler N, Trajanoski Z, Mouritzen P, Birklein F, et al. microRNAs in nociceptive circuits as predictors of future clinical applications. Frontiers in Molecular Neuroscience. 6: 33. PMID 24151455 DOI: 10.3389/fnmol.2013.00033  0.96
2013 Nockemann D, Rouault M, Labuz D, Hublitz P, McKnelly K, Reis FC, Stein C, Heppenstall PA. The K(+) channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia. Embo Molecular Medicine. 5: 1263-77. PMID 23818182 DOI: 10.1002/emmm.201201980  0.96
2013 Kalebic N, Sorrentino S, Perlas E, Bolasco G, Martinez C, Heppenstall PA. αTAT1 is the major α-tubulin acetyltransferase in mice. Nature Communications. 4: 1962. PMID 23748901 DOI: 10.1038/ncomms2962  0.96
2013 Batti L, Mukhtarov M, Audero E, Ivanov A, Paolicelli RC, Zurborg S, Gross C, Bregestovski P, Heppenstall PA. Transgenic mouse lines for non-invasive ratiometric monitoring of intracellular chloride. Frontiers in Molecular Neuroscience. 6: 11. PMID 23734096 DOI: 10.3389/fnmol.2013.00011  0.96
2013 Wildner H, Das Gupta R, Bröhl D, Heppenstall PA, Zeilhofer HU, Birchmeier C. Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7299-307. PMID 23616538 DOI: 10.1523/JNEUROSCI.0491-13.2013  0.96
2013 Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Corrêa IR, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, et al. A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins. Nature Chemistry. 5: 132-9. PMID 23344448 DOI: 10.1038/nchem.1546  0.96
2013 Kalebic N, Martinez C, Perlas E, Hublitz P, Bilbao-Cortes D, Fiedorczuk K, Andolfo A, Heppenstall PA. Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity. Molecular and Cellular Biology. 33: 1114-23. PMID 23275437 DOI: 10.1128/MCB.01044-12  0.96
2013 Wang H, Schupp M, Zurborg S, Heppenstall PA. Residues in the pore region of Drosophila transient receptor potential A1 dictate sensitivity to thermal stimuli. The Journal of Physiology. 591: 185-201. PMID 23027824 DOI: 10.1113/jphysiol.2012.242842  0.96
2012 Schmidt Y, Labuz D, Heppenstall PA, Machelska H. Cutaneous nociceptors lack sensitisation, but reveal μ-opioid receptor-mediated reduction in excitability to mechanical stimulation in neuropathy. Molecular Pain. 8: 81. PMID 23116256 DOI: 10.1186/1744-8069-8-81  0.96
2012 Lapatsina L, Jira JA, Smith ES, Poole K, Kozlenkov A, Bilbao D, Lewin GR, Heppenstall PA. Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons. Open Biology. 2: 120096. PMID 22773952 DOI: 10.1098/rsob.120096  0.96
2012 Topalidou I, Keller C, Kalebic N, Nguyen KC, Somhegyi H, Politi KA, Heppenstall P, Hall DH, Chalfie M. Genetically separable functions of the MEC-17 tubulin acetyltransferase affect microtubule organization. Current Biology : Cb. 22: 1057-65. PMID 22658602 DOI: 10.1016/j.cub.2012.03.066  0.96
2011 Zurborg S, Piszczek A, Martínez C, Hublitz P, Al Banchaabouchi M, Moreira P, Perlas E, Heppenstall PA. Generation and characterization of an Advillin-Cre driver mouse line. Molecular Pain. 7: 66. PMID 21906401 DOI: 10.1186/1744-8069-7-66  0.96
2010 Goswami C, Kuhn J, Heppenstall PA, Hucho T. Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. Plos One. 5: e11654. PMID 20657843 DOI: 10.1371/journal.pone.0011654  0.96
2009 Caspani O, Zurborg S, Labuz D, Heppenstall PA. The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain. Plos One. 4: e7383. PMID 19812688 DOI: 10.1371/journal.pone.0007383  0.96
2009 Caspani O, Heppenstall PA. TRPA1 and cold transduction: an unresolved issue? The Journal of General Physiology. 133: 245-9. PMID 19237589 DOI: 10.1085/jgp.200810136  0.96
2008 Park TJ, Lu Y, Jüttner R, Smith ES, Hu J, Brand A, Wetzel C, Milenkovic N, Erdmann B, Heppenstall PA, Laurito CE, Wilson SP, Lewin GR. Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber). Plos Biology. 6: e13. PMID 18232734 DOI: 10.1371/journal.pbio.0060013  0.96
2007 Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA. Direct activation of the ion channel TRPA1 by Ca2+. Nature Neuroscience. 10: 277-9. PMID 17259981 DOI: 10.1038/nn1843  0.96
2007 Wetzel C, Hu J, Riethmacher D, Benckendorff A, Harder L, Eilers A, Moshourab R, Kozlenkov A, Labuz D, Caspani O, Erdmann B, Machelska H, Heppenstall PA, Lewin GR. A stomatin-domain protein essential for touch sensation in the mouse. Nature. 445: 206-9. PMID 17167420 DOI: 10.1038/nature05394  0.96
2007 Endres-Becker J, Heppenstall PA, Mousa SA, Labuz D, Oksche A, Schäfer M, Stein C, Zöllner C. Mu-opioid receptor activation modulates transient receptor potential vanilloid 1 (TRPV1) currents in sensory neurons in a model of inflammatory pain. Molecular Pharmacology. 71: 12-8. PMID 17005903 DOI: 10.1124/mol.106.026740  0.96
2006 Heppenstall PA, Lewin GR. A role for T-type Ca2+ channels in mechanosensation. Cell Calcium. 40: 165-74. PMID 16777219 DOI: 10.1016/j.ceca.2006.04.021  0.96
2004 Hartmann B, Ahmadi S, Heppenstall PA, Lewin GR, Schott C, Borchardt T, Seeburg PH, Zeilhofer HU, Sprengel R, Kuner R. The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain. Neuron. 44: 637-50. PMID 15541312 DOI: 10.1016/j.neuron.2004.10.029  0.96
2003 Machelska H, Heppenstall PA, Stein C. Breaking the pain barrier. Nature Medicine. 9: 1353-4. PMID 14595426 DOI: 10.1038/nm1103-1353  0.96
2003 Shin JB, Martinez-Salgado C, Heppenstall PA, Lewin GR. A T-type calcium channel required for normal function of a mammalian mechanoreceptor. Nature Neuroscience. 6: 724-30. PMID 12808460 DOI: 10.1038/nn1076  0.96
2002 Schmidt H, Werner M, Heppenstall PA, Henning M, Moré MI, Kühbandner S, Lewin GR, Hofmann F, Feil R, Rathjen FG. cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons. The Journal of Cell Biology. 159: 489-98. PMID 12417579 DOI: 10.1083/jcb.200207058  0.96
2002 Müller T, Brohmann H, Pierani A, Heppenstall PA, Lewin GR, Jessell TM, Birchmeier C. The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord. Neuron. 34: 551-62. PMID 12062039 DOI: 10.1016/S0896-6273(02)00689-X  0.96
2001 Heppenstall PA, Lewin GR. BDNF but not NT-4 is required for normal flexion reflex plasticity and function. Proceedings of the National Academy of Sciences of the United States of America. 98: 8107-12. PMID 11438749 DOI: 10.1073/pnas.141015098  0.96
2000 Heppenstall PA, Lewin GR. Neurotrophins, nociceptors and pain. Current Opinion in Anaesthesiology. 13: 573-6. PMID 17016360 DOI: 10.1097/00001503-200010000-00015  0.96
2000 Price MP, Lewin GR, McIlwrath SL, Cheng C, Xie J, Heppenstall PA, Stucky CL, Mannsfeldt AG, Brennan TJ, Drummond HA, Qiao J, Benson CJ, Tarr DE, Hrstka RF, Yang B, et al. The mammalian sodium channel BNC1 is required for normal touch sensation. Nature. 407: 1007-11. PMID 11069180 DOI: 10.1038/35039512  0.96
2000 Pesquero JB, Araujo RC, Heppenstall PA, Stucky CL, Silva JA, Walther T, Oliveira SM, Pesquero JL, Paiva AC, Calixto JB, Lewin GR, Bader M. Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 8140-5. PMID 10859349 DOI: 10.1073/pnas.120035997  0.96
1997 Heppenstall PA, Fleetwood-Walker SM. Glycine receptor regulation of neurokinin1 receptor function in rat dorsal horn neurones. Neuroreport. 8: 3109-12. PMID 9331923  0.96
1997 Heppenstall PA, Fleetwood-Walker SM. The glycine site of the NMDA receptor contributes to neurokinin1 receptor agonist facilitation of NMDA receptor agonist-evoked activity in rat dorsal horn neurons. Brain Research. 744: 235-45. PMID 9027383 DOI: 10.1016/S0006-8993(96)01065-7  0.96
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