Bertil B. Fredholm, PhD - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Adenosine receptors
Website:
http://ki.se/ki/jsp/polopoly.jsp?d=33393&l=en

431 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Fredholm BB, Svenningsson P. Why target brain adenosine receptors? A historical perspective. Parkinsonism & Related Disorders. 80: S3-S6. PMID 33349578 DOI: 10.1016/j.parkreldis.2020.09.027  0.595
2019 Fredholm BB, Frenguelli BG, Hills R, IJzerman AP, Jacobson KA, Klotz K, Linden J, Müller CE, Schwabe U, Stiles GL. Adenosine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f3/2019.4  0.519
2017 Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Adenosine and Sleep. Handbook of Experimental Pharmacology. PMID 28646346 DOI: 10.1007/164_2017_36  0.327
2017 Peleli M, Fredholm BB, Sobrevia L, Carlström M. Pharmacological targeting of adenosine receptor signaling. Molecular Aspects of Medicine. PMID 28088486 DOI: 10.1016/j.mam.2016.12.002  0.423
2016 Fredholm BB, Yang J, Wang Y. Low, but not high, dose caffeine is a readily available probe for adenosine actions. Molecular Aspects of Medicine. PMID 27915051 DOI: 10.1016/j.mam.2016.11.011  0.348
2016 Yang T, Zollbrecht C, Winerdal ME, Zhuge Z, Zhang XM, Terrando N, Checa A, Sällström J, Wheelock CE, Winqvist O, Harris RA, Larsson E, Persson AE, Fredholm BB, Carlström M. Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. Journal of the American Heart Association. 5. PMID 27431647 DOI: 10.1161/Jaha.116.003868  0.365
2015 Winerdal M, Winerdal ME, Wang YQ, Fredholm BB, Winqvist O, Ådén U. Adenosine A1 receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury. Purinergic Signalling. PMID 26608888 DOI: 10.1007/s11302-015-9482-3  0.357
2015 Yang T, Gao X, Sandberg M, Zollbrecht C, Zhang XM, Hezel M, Liu M, Peleli M, Lai EY, Harris RA, Persson AE, Fredholm BB, Jansson L, Carlström M. Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. Diabetologia. 58: 1610-20. PMID 25835725 DOI: 10.1007/s00125-015-3570-3  0.361
2014 Fredholm BB. Adenosine--a physiological or pathophysiological agent? Journal of Molecular Medicine (Berlin, Germany). 92: 201-6. PMID 24362516 DOI: 10.1007/s00109-013-1101-6  0.388
2014 Yang J, Zheng X, Haugen F, Darè E, Lövdahl C, Schulte G, Fredholm BB, Valen G. Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors. Acta Physiologica (Oxford, England). 210: 590-9. PMID 24119187 DOI: 10.1111/Apha.12176  0.656
2013 Chen JF, Eltzschig HK, Fredholm BB. Adenosine receptors as drug targets--what are the challenges? Nature Reviews. Drug Discovery. 12: 265-86. PMID 23535933 DOI: 10.1038/Nrd3955  0.444
2012 Fredholm BB. Rethinking the purinergic neuron-glia connection. Proceedings of the National Academy of Sciences of the United States of America. 109: 5913-4. PMID 22509008 DOI: 10.1073/pnas.1203764109  0.369
2011 Cipriani R, Villa P, Chece G, Lauro C, Paladini A, Micotti E, Perego C, De Simoni MG, Fredholm BB, Eusebi F, Limatola C. CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16327-35. PMID 22072684 DOI: 10.1523/JNEUROSCI.3611-11.2011  0.364
2011 Gao X, Patzak A, Sendeski M, Scheffer PG, Teerlink T, Sällström J, Fredholm BB, Persson AE, Carlström M. Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1669-81. PMID 21975649 DOI: 10.1152/ajpregu.00268.2011  0.315
2011 Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10067-75. PMID 21734299 DOI: 10.1523/Jneurosci.6730-10.2011  0.405
2011 Masino SA, Li T, Theofilas P, Sandau US, Ruskin DN, Fredholm BB, Geiger JD, Aronica E, Boison D. A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors. The Journal of Clinical Investigation. 121: 2679-83. PMID 21701065 DOI: 10.1172/JCI57813  0.332
2011 Fredholm BB, Johansson S, Wang YQ. Adenosine and the regulation of metabolism and body temperature. Advances in Pharmacology (San Diego, Calif.). 61: 77-94. PMID 21586356 DOI: 10.1016/B978-0-12-385526-8.00003-5  0.338
2011 Burnstock G, Fredholm BB, Verkhratsky A. Adenosine and ATP receptors in the brain. Current Topics in Medicinal Chemistry. 11: 973-1011. PMID 21401499 DOI: 10.2174/156802611795347627  0.446
2011 Fredholm BB, IJzerman AP, Jacobson KA, Linden J, Müller CE. International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update. Pharmacological Reviews. 63: 1-34. PMID 21303899 DOI: 10.1124/Pr.110.003285  0.56
2011 Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J. Links between Insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans Diabetes. 60: 669-679. PMID 21270276 DOI: 10.2337/Db10-1070  0.333
2011 Yang GK, Yip L, Fredholm BB, Kieffer TJ, Kwok YN. Involvement of adenosine signaling in controlling the release of ghrelin from the mouse stomach. The Journal of Pharmacology and Experimental Therapeutics. 336: 77-86. PMID 20876230 DOI: 10.1124/Jpet.110.171280  0.479
2011 Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB, Schwarzschild MA. Deletion of adenosine A₁ or A(â‚‚A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease. Brain Research. 1367: 310-8. PMID 20828543 DOI: 10.1016/J.Brainres.2010.08.099  0.38
2011 Fredholm BB. Physiological and pathophysiological roles of adenosine Sleep and Biological Rhythms. 9: 24-28. DOI: 10.1111/j.1479-8425.2010.00460.x  0.379
2010 Kenakin T, Agnati LF, Caron M, Fredholm B, Guidoli D, Kobilka B, Lefkowitz RW, Lohse M, Woods A, Fuxe K. International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached? Journal of Receptor and Signal Transduction Research. 30: 284-6. PMID 20858022 DOI: 10.3109/10799893.2010.512438  0.604
2010 Li L, Hao JX, Fredholm BB, Schulte G, Wiesenfeld-Hallin Z, Xu XJ. Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice. Neuroscience. 170: 923-8. PMID 20678550 DOI: 10.1016/J.Neuroscience.2010.07.045  0.642
2010 Piccinin S, Di Angelantonio S, Piccioni A, Volpini R, Cristalli G, Fredholm BB, Limatola C, Eusebi F, Ragozzino D. CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes. Journal of Neuroimmunology. 224: 85-92. PMID 20570369 DOI: 10.1016/j.jneuroim.2010.05.012  0.337
2010 Minelli A, Grottelli S, Corazzi L, Bellezza I, Rambotti MG, Emiliani C, Fredholm BB. Adenosine A(1) receptors contribute to mitochondria vulnerability to pro-oxidant stressors. Mitochondrion. 10: 369-79. PMID 20230919 DOI: 10.1016/j.mito.2010.03.004  0.437
2010 Lauro C, Cipriani R, Catalano M, Trettel F, Chece G, Brusadin V, Antonilli L, van Rooijen N, Eusebi F, Fredholm BB, Limatola C. Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1550-9. PMID 20200508 DOI: 10.1038/npp.2010.26  0.38
2010 Kara FM, Chitu V, Sloane J, Axelrod M, Fredholm BB, Stanley ER, Cronstein BN. Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2325-33. PMID 20181934 DOI: 10.1096/Fj.09-147447  0.317
2010 Sawynok J, Reid AR, Fredholm BB. Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A1 receptors: insights using knockout mice. Neuroscience Letters. 473: 178-81. PMID 20176083 DOI: 10.1016/j.neulet.2010.02.028  0.437
2010 Fredholm BB. Adenosine receptors as drug targets. Experimental Cell Research. 316: 1284-8. PMID 20153317 DOI: 10.1016/j.yexcr.2010.02.004  0.486
2010 Wang Y, Yang JN, Arner A, Boels PJ, Fredholm BB. Adenosine A(1) receptors and vascular reactivity. Acta Physiologica (Oxford, England). 199: 211-20. PMID 20132147 DOI: 10.1111/j.1748-1716.2010.02093.x  0.405
2010 Yang JN, Wang Y, Garcia-Roves PM, Björnholm M, Fredholm BB. Adenosine A(3) receptors regulate heart rate, motor activity and body temperature. Acta Physiologica (Oxford, England). 199: 221-30. PMID 20121716 DOI: 10.1111/j.1748-1716.2010.02091.x  0.315
2010 Kara FM, Doty SB, Boskey A, Goldring S, Zaidi M, Fredholm BB, Cronstein BN. Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice. Arthritis and Rheumatism. 62: 534-41. PMID 20112380 DOI: 10.1002/Art.27219  0.324
2010 Boison D, Chen JF, Fredholm BB. Adenosine signaling and function in glial cells. Cell Death and Differentiation. 17: 1071-82. PMID 19763139 DOI: 10.1038/Cdd.2009.131  0.312
2009 Fredholm BB, Jacobson KA. Adenosine Receptors: The Contributions by John W. Daly. Heterocycles. 79: 73-83. PMID 26113768 DOI: 10.3987/Com-08-S(D)Memoire-2  0.565
2009 Maggi L, Trettel F, Scianni M, Bertollini C, Eusebi F, Fredholm BB, Limatola C. LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R). Journal of Neuroimmunology. 215: 36-42. PMID 19709758 DOI: 10.1016/j.jneuroim.2009.07.016  0.349
2009 Salehi A, Parandeh F, Fredholm BB, Grapengiesser E, Hellman B. Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin. Life Sciences. 85: 470-6. PMID 19682463 DOI: 10.1016/j.lfs.2009.08.001  0.353
2009 Yu L, Coelho JE, Zhang X, Fu Y, Tillman A, Karaoz U, Fredholm BB, Weng Z, Chen JF. Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling. Physiological Genomics. 37: 199-210. PMID 19258493 DOI: 10.1152/Physiolgenomics.90353.2008  0.35
2009 Conte C, Grottelli S, Prudenzi E, Bellezza I, Fredholm BB, Minelli A. A(1) and A(3) adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of gamma-glutamylcysteine ligase. Free Radical Research. 43: 304-11. PMID 19229670 DOI: 10.1080/10715760802712616  0.453
2009 Yang JN, Björklund O, Lindström-Törnqvist K, Lindgren E, Eriksson TM, Kahlström J, Chen JF, Schwarzschild MA, Tobler I, Fredholm BB. Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine. Journal of Applied Physiology (Bethesda, Md. : 1985). 106: 631-9. PMID 19036889 DOI: 10.1152/Japplphysiol.90971.2008  0.318
2009 Ljunggren Ö, Johansson H, Ljunghall S, Fredholm BB, Lerner UH. Bradykinin induces formation of inositol phosphates and causes an increase in cytoplasmic Ca2+ in the osteoblastic cell line MC3T3-E1. Journal of Bone and Mineral Research. 6: 443-452. PMID 1648860 DOI: 10.1002/Jbmr.5650060504  0.349
2009 Fredholm BB, Möllby R, Anderson P, Malmquist T, Smyth CJ. Inhibition of Noradrenaline-Stimulated Lipolysis and Cyclic AMP Accumulation in Isolated Rat Adipocytes by Purified Phospholipase C and Theta-Toxin from Clostridium Perfringens Pharmacology & Toxicology. 42: 23-34. PMID 203164 DOI: 10.1111/J.1600-0773.1978.Tb02167.X  0.327
2009 Fredholm BB, Jacobson KA. Adenosine receptors: The contributions by John W. Daly Heterocycles. 79: 73-83. DOI: 10.3987/COM-08-S(D)Memoire-2  0.505
2008 Björklund O, Kahlström J, Salmi P, Fredholm BB. Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring. Plos One. 3: e3977. PMID 19092996 DOI: 10.1371/journal.pone.0003977  0.332
2008 Oishi Y, Huang ZL, Fredholm BB, Urade Y, Hayaishi O. Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep. Proceedings of the National Academy of Sciences of the United States of America. 105: 19992-7. PMID 19066225 DOI: 10.1073/Pnas.0810926105  0.321
2008 Björklund O, Halldner-Henriksson L, Yang J, Eriksson TM, Jacobson MA, Daré E, Fredholm BB. Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice. Physiology & Behavior. 95: 668-76. PMID 18930070 DOI: 10.1016/j.physbeh.2008.09.018  0.444
2008 Roseti C, Martinello K, Fucile S, Piccari V, Mascia A, Di Gennaro G, Quarato PP, Manfredi M, Esposito V, Cantore G, Arcella A, Simonato M, Fredholm BB, Limatola C, Miledi R, et al. Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 105: 15118-23. PMID 18809912 DOI: 10.1073/pnas.0807277105  0.423
2008 Johansson SM, Lindgren E, Yang JN, Herling AW, Fredholm BB. Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin. European Journal of Pharmacology. 597: 92-101. PMID 18789919 DOI: 10.1016/j.ejphar.2008.08.022  0.449
2008 Björklund O, Shang M, Tonazzini I, Daré E, Fredholm BB. Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage. European Journal of Pharmacology. 596: 6-13. PMID 18727925 DOI: 10.1016/j.ejphar.2008.08.002  0.48
2008 Salehi SA, Parandeh F, Fredholm B, Grapengiesser E, Hellman B. Adenosine A, receptors modulate glucose-induced pulses of islet hormone release Diabetologia. 51: 195-195. PMID 18704365 DOI: 10.1007/S00125-008-1117-6  0.37
2008 Brand F, Klutz AM, Jacobson KA, Fredholm BB, Schulte G. Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC. European Journal of Pharmacology. 590: 36-42. PMID 18603240 DOI: 10.1016/J.Ejphar.2008.05.036  0.747
2008 Sawynok J, Reid AR, Fredholm BB. Caffeine reverses antinociception by amitriptyline in wild type mice but not in those lacking adenosine A1 receptors. Neuroscience Letters. 440: 181-4. PMID 18562097 DOI: 10.1016/j.neulet.2008.05.074  0.371
2008 Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, Tilley SL. Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. The Journal of Allergy and Clinical Immunology. 122: 107-13, 113.e1-7. PMID 18472152 DOI: 10.1016/J.Jaci.2008.03.026  0.37
2008 Xia S, Dun XP, Hu PS, Kjaer S, Zheng K, Qian Y, Solén C, Xu T, Fredholm B, Hökfelt T, Xu ZQ. Postendocytotic traffic of the galanin R1 receptor: a lysosomal signal motif on the cytoplasmic terminus. Proceedings of the National Academy of Sciences of the United States of America. 105: 5609-13. PMID 18385373 DOI: 10.1073/Pnas.0801456105  0.557
2008 Chen L, Fredholm BB, Jondal M. Adenosine, through the A1 receptor, inhibits vesicular MHC class I cross-presentation by resting DC. Molecular Immunology. 45: 2247-54. PMID 18178251 DOI: 10.1016/j.molimm.2007.11.016  0.469
2008 Minelli A, Bellezza I, Collodel G, Fredholm BB. Promiscuous coupling and involvement of protein kinase C and extracellular signal-regulated kinase 1/2 in the adenosine A1 receptor signalling in mammalian spermatozoa. Biochemical Pharmacology. 75: 931-41. PMID 18054348 DOI: 10.1016/j.bcp.2007.10.024  0.448
2007 Li T, Quan Lan J, Fredholm BB, Simon RP, Boison D. Adenosine dysfunction in astrogliosis: cause for seizure generation? Neuron Glia Biology. 3: 353-66. PMID 18634566 DOI: 10.1017/S1740925X0800015X  0.334
2007 Ohta A, Lukashev D, Jackson EK, Fredholm BB, Sitkovsky M. 1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism. Journal of Immunology (Baltimore, Md. : 1950). 179: 7431-8. PMID 18025187 DOI: 10.4049/Jimmunol.179.11.7431  0.309
2007 Björklund O, Kahlström J, Salmi P, Ogren SO, Vahter M, Chen JF, Fredholm BB, Daré E. The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration. Toxicology. 241: 119-33. PMID 17920182 DOI: 10.1016/J.Tox.2007.08.092  0.446
2007 Fredholm BB, Chern Y, Franco R, Sitkovsky M. Aspects of the general biology of adenosine A2A signaling. Progress in Neurobiology. 83: 263-76. PMID 17804147 DOI: 10.1016/J.Pneurobio.2007.07.005  0.452
2007 Daré E, Schulte G, Karovic O, Hammarberg C, Fredholm BB. Modulation of glial cell functions by adenosine receptors. Physiology & Behavior. 92: 15-20. PMID 17574632 DOI: 10.1016/J.Physbeh.2007.05.031  0.713
2007 Wendler CC, Amatya S, McClaskey C, Ghatpande S, Fredholm BB, Rivkees SA. A1 adenosine receptors play an essential role in protecting the embryo against hypoxia. Proceedings of the National Academy of Sciences of the United States of America. 104: 9697-702. PMID 17522253 DOI: 10.1073/Pnas.0703557104  0.343
2007 Fredholm BB, Hökfelt T, Milligan G. G-protein-coupled receptors: an update. Acta Physiologica (Oxford, England). 190: 3-7. PMID 17428227 DOI: 10.1111/j.1365-201X.2007.01689.x  0.553
2007 Schulte G, Fredholm B. A Nordic meeting on G-protein-coupled receptors: From molecular aspects to novel therapy Acta Physiologica. 190: 1. PMID 17428226 DOI: 10.1111/J.1365-201X.2007.01686.X  0.624
2007 Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death and Differentiation. 14: 1315-23. PMID 17396131 DOI: 10.1038/sj.cdd.4402132  0.426
2007 Tabata T, Kawakami D, Hashimoto K, Kassai H, Yoshida T, Hashimotodani Y, Fredholm BB, Sekino Y, Aiba A, Kano M. G protein-independent neuromodulatory action of adenosine on metabotropic glutamate signalling in mouse cerebellar Purkinje cells. The Journal of Physiology. 581: 693-708. PMID 17379632 DOI: 10.1113/jphysiol.2007.129866  0.375
2007 Chergui K, Fredholm BB, Svenningsson P. Many ways to Rome - multiple approaches to novel drugs Current Opinion in Pharmacology. 7: 1-2. DOI: 10.1016/j.coph.2006.12.002  0.411
2006 Lai EY, Patzak A, Steege A, Mrowka R, Brown R, Spielmann N, Persson PB, Fredholm BB, Persson AE. Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction. Kidney International. 70: 690-8. PMID 16807541 DOI: 10.1038/sj.ki.5001650  0.415
2006 Fedele DE, Li T, Lan JQ, Fredholm BB, Boison D. Adenosine A1 receptors are crucial in keeping an epileptic focus localized. Experimental Neurology. 200: 184-90. PMID 16750195 DOI: 10.1016/j.expneurol.2006.02.133  0.413
2006 Schotanus SM, Fredholm BB, Chergui K. NMDA depresses glutamatergic synaptic transmission in the striatum through the activation of adenosine A1 receptors: evidence from knockout mice. Neuropharmacology. 51: 272-82. PMID 16712880 DOI: 10.1016/j.neuropharm.2006.03.025  0.407
2006 Wu WP, Hao JX, Fredholm BB, Wiesenfeld-Hallin Z, Xu XJ. Effect of acute and chronic administration of caffeine on pain-like behaviors in rats with partial sciatic nerve injury. Neuroscience Letters. 402: 164-6. PMID 16644114 DOI: 10.1016/j.neulet.2006.03.065  0.333
2006 Jonsson M, Dabrowski M, Gurley DA, Larsson O, Johnson EC, Fredholm BB, Eriksson LI. Activation and inhibition of human muscular and neuronal nicotinic acetylcholine receptors by succinylcholine. Anesthesiology. 104: 724-33. PMID 16571968 DOI: 10.1097/00000542-200604000-00017  0.695
2006 Brown RD, Thorén P, Steege A, Mrowka R, Sällström J, Skøtt O, Fredholm BB, Persson AE. Influence of the adenosine A1 receptor on blood pressure regulation and renin release. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R1324-9. PMID 16357099 DOI: 10.1152/ajpregu.00313.2005  0.337
2006 Kuzmin A, Johansson B, Gimenez L, Ogren SO, Fredholm BB. Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 129-36. PMID 16054807 DOI: 10.1016/j.euroneuro.2005.07.001  0.416
2005 NergÃ¥rdh R, Oerther S, Fredholm BB. Differences between A 68930 and SKF 82958 could suggest synergistic roles of D1 and D5 receptors. Pharmacology, Biochemistry, and Behavior. 82: 495-505. PMID 16318870 DOI: 10.1016/j.pbb.2005.09.017  0.425
2005 Andersson M, Usiello A, Borgkvist A, Pozzi L, Dominguez C, Fienberg AA, Svenningsson P, Fredholm BB, Borrelli E, Greengard P, Fisone G. Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8432-8. PMID 16162925 DOI: 10.1523/Jneurosci.1289-05.2005  0.698
2005 Kim M, Yu ZX, Fredholm BB, Rivkees SA. Susceptibility of the developing brain to acute hypoglycemia involving A1 adenosine receptor activation. American Journal of Physiology. Endocrinology and Metabolism. 289: E562-9. PMID 16150954 DOI: 10.1152/ajpendo.00112.2005  0.343
2005 Salmi P, Chergui K, Fredholm BB. Adenosine-dopamine interactions revealed in knockout mice. Journal of Molecular Neuroscience : Mn. 26: 239-44. PMID 16012197 DOI: 10.1385/JMN:26:2-3:239  0.454
2005 Johansson S, Fredholm BB, Hjort C, Morein T, Kull B, Hu PS. Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor. Biochemical Pharmacology. 70: 598-605. PMID 15979585 DOI: 10.1016/j.bcp.2005.05.023  0.489
2005 Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nature Neuroscience. 8: 858-9. PMID 15965471 DOI: 10.1038/Nn1491  0.478
2005 Giménez-Llort L, Masino SA, Diao L, Fernández-Teruel A, Tobeña A, Halldner L, Fredholm BB. Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly. Synapse (New York, N.Y.). 57: 8-16. PMID 15858837 DOI: 10.1002/syn.20146  0.334
2005 Fredholm BB, Chen JF, Masino SA, Vaugeois JM. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annual Review of Pharmacology and Toxicology. 45: 385-412. PMID 15822182 DOI: 10.1146/Annurev.Pharmtox.45.120403.095731  0.366
2005 Fredholm BB, Chen JF, Cunha RA, Svenningsson P, Vaugeois JM. Adenosine and brain function. International Review of Neurobiology. 63: 191-270. PMID 15797469 DOI: 10.1016/S0074-7742(05)63007-3  0.683
2005 Kukley M, Schwan M, Fredholm BB, Dietrich D. The role of extracellular adenosine in regulating mossy fiber synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2832-7. PMID 15772343 DOI: 10.1523/JNEUROSCI.4260-04.2005  0.344
2005 Wu WP, Hao JX, Halldner L, Lövdahl C, DeLander GE, Wiesenfeld-Hallin Z, Fredholm BB, Xu XJ. Increased nociceptive response in mice lacking the adenosine A1 receptor. Pain. 113: 395-404. PMID 15661449 DOI: 10.1016/j.pain.2004.11.020  0.399
2005 Ghanem E, Lövdahl C, Daré E, Ledent C, Fredholm BB, Boeynaems JM, Van Driessche W, Beauwens R. Luminal adenosine stimulates chloride secretion through A1 receptor in mouse jejunum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G972-7. PMID 15637180 DOI: 10.1152/ajpgi.00346.2004  0.451
2004 Schulte G, Sommerschild H, Yang J, Tokuno S, Goiny M, Lövdahl C, Johansson B, Fredholm BB, Valen G. Adenosine A receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia. Acta Physiologica Scandinavica. 182: 133-43. PMID 15450109 DOI: 10.1111/J.1365-201X.2004.01350.X  0.627
2004 Halldner L, Lopes LV, Daré E, Lindström K, Johansson B, Ledent C, Cunha RA, Fredholm BB. Binding of adenosine receptor ligands to brain of adenosine receptor knock-out mice: evidence that CGS 21680 binds to A1 receptors in hippocampus. Naunyn-Schmiedeberg's Archives of Pharmacology. 370: 270-8. PMID 15378230 DOI: 10.1007/s00210-004-0970-1  0.622
2004 Olsson T, Cronberg T, Rytter A, Asztély F, Fredholm BB, Smith ML, Wieloch T. Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro. The European Journal of Neuroscience. 20: 1197-204. PMID 15341591 DOI: 10.1111/J.1460-9568.2004.03564.X  0.386
2004 Jonsson M, Wyon N, Lindahl SG, Fredholm BB, Eriksson LI. Neuromuscular blocking agents block carotid body neuronal nicotinic acetylcholine receptors. European Journal of Pharmacology. 497: 173-80. PMID 15306202 DOI: 10.1016/j.ejphar.2004.06.052  0.339
2004 Halldner L, Adén U, Dahlberg V, Johansson B, Ledent C, Fredholm BB. The adenosine A1 receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion: a study in mice lacking adenosine A1 and/or A2A receptors. Neuropharmacology. 46: 1008-17. PMID 15081797 DOI: 10.1016/j.neuropharm.2004.01.014  0.448
2004 Lopes LV, Halldner L, Rebola N, Johansson B, Ledent C, Chen JF, Fredholm BB, Cunha RA. Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice. British Journal of Pharmacology. 141: 1006-14. PMID 14993095 DOI: 10.1038/sj.bjp.0705692  0.615
2004 Minelli A, Liguori L, Bellazza I, Mannucci R, Johansson B, Fredholm BB. Involvement of A1 adenosine receptors in the acquisition of fertilizing capacity. Journal of Andrology. 25: 286-92. PMID 14760015 DOI: 10.1002/J.1939-4640.2004.Tb02789.X  0.319
2004 Hammarberg C, Fredholm BB, Schulte G. Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase. Biochemical Pharmacology. 67: 129-34. PMID 14667935 DOI: 10.1016/J.Bcp.2003.08.031  0.688
2004 Fredholm B. S.23.01 Caffeine as an adenosine receptor antagonist European Neuropsychopharmacology. 14: S156-S157. DOI: 10.1016/S0924-977X(04)80070-1  0.346
2004 Hammarberg C, Fredholm BB, Schulte G. Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3′-kinase Biochemical Pharmacology. 67: 129-134. DOI: 10.1016/j.bcp.2003.08.031  0.624
2003 Svenningsson P, Fredholm BB. Exciting news about A2A receptors. Neurology. 61: S10-1. PMID 14663002 DOI: 10.1212/01.WNL.0000095203.52609.6A  0.598
2003 Fredholm BB, Svenningsson P. Adenosine-dopamine interactions: development of a concept and some comments on therapeutic possibilities. Neurology. 61: S5-9. PMID 14663001 DOI: 10.1212/01.WNL.0000095204.89871.FF  0.609
2003 Schulte G, Robertson B, Fredholm BB, DeLander GE, Shortland P, Molander C. Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations. Neuroscience. 121: 907-16. PMID 14580941 DOI: 10.1016/S0306-4522(03)00480-9  0.64
2003 Schulte G, Fredholm BB. The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. Experimental Cell Research. 290: 168-76. PMID 14516797 DOI: 10.1016/S0014-4827(03)00324-0  0.673
2003 Turner CP, Seli M, Ment L, Stewart W, Yan H, Johansson B, Fredholm BB, Blackburn M, Rivkees SA. A1 adenosine receptors mediate hypoxia-induced ventriculomegaly. Proceedings of the National Academy of Sciences of the United States of America. 100: 11718-22. PMID 12975523 DOI: 10.1073/Pnas.1931975100  0.384
2003 Fredholm BB. Adenosine receptors as targets for drug development. Drug News & Perspectives. 16: 283-9. PMID 12942159 DOI: 10.1358/dnp.2003.16.5.829316  0.432
2003 Hammarberg C, Schulte G, Fredholm BB. Evidence for functional adenosine A3 receptors in microglia cells. Journal of Neurochemistry. 86: 1051-4. PMID 12887702 DOI: 10.1046/J.1471-4159.2003.01919.X  0.71
2003 Lynge J, Schulte G, Nordsborg N, Fredholm BB, Hellsten Y. Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells. Biochemical and Biophysical Research Communications. 307: 180-7. PMID 12849998 DOI: 10.1016/S0006-291X(03)01125-2  0.679
2003 Schulte G, Fredholm BB. Signalling from adenosine receptors to mitogen-activated protein kinases. Cellular Signalling. 15: 813-27. PMID 12834807 DOI: 10.1016/S0898-6568(03)00058-5  0.707
2003 Fredholm BB, Assender JW, Irenius E, Kodama N, Saito N. Synergistic effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization and PKC translocation in DDT1 MF-2 cells. Cellular and Molecular Neurobiology. 23: 379-400. PMID 12825834 DOI: 10.1023/A:1023644822539  0.477
2003 Fredholm BB, Cunha RA, Svenningsson P. Pharmacology of adenosine A2A receptors and therapeutic applications. Current Topics in Medicinal Chemistry. 3: 413-26. PMID 12570759 DOI: 10.2174/1568026033392200  0.7
2003 Lopes LV, Rebola N, Costenla AR, Halldner L, Jacobson MA, Oliveira CR, Richardson PJ, Fredholm BB, Ribeiro JA, Cunha RA. Adenosine A3 receptors in the rat hippocampus: Lack of interaction with A1 receptors Drug Development Research. 58: 428-438. DOI: 10.1002/ddr.10188  0.623
2003 Fredholm BB, Halldner L, Johansson C, Schulte G, Lövdahl C, Thorén P, Dunwiddie TV, Masino SA, Poelchen W, Diao L, Illes P, Zahniser NR, Valen G, Tokuno S, Sommerschild H, et al. Consequences of eliminating adenosine A1 receptors in mice Drug Development Research. 58: 350-353. DOI: 10.1002/Ddr.10170  0.632
2003 Fredholm BB. Caffeine and the biological role of adenosine receptors | Cafeína y función biológica de los receptores de adenosina Anales De La Real Academia Nacional De Farmacia. 69: 685-717.  0.342
2002 Schulte G, Fredholm BB. Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2. Molecular Pharmacology. 62: 1137-46. PMID 12391277 DOI: 10.1124/Mol.62.5.1137  0.691
2002 Masino SA, Diao L, Illes P, Zahniser NR, Larson GA, Johansson B, Fredholm BB, Dunwiddie TV. Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors. The Journal of Pharmacology and Experimental Therapeutics. 303: 356-63. PMID 12235271 DOI: 10.1124/Jpet.102.036731  0.467
2002 Wu WP, Hao JX, Halldner-Henriksson L, Xu XJ, Jacobson MA, Wiesenfeld-Hallin Z, Fredholm BB. Decreased inflammatory pain due to reduced carrageenan-induced inflammation in mice lacking adenosine A3 receptors. Neuroscience. 114: 523-7. PMID 12220556 DOI: 10.1016/S0306-4522(02)00273-7  0.345
2002 Giménez-Llort L, Fernández-Teruel A, Escorihuela RM, Fredholm BB, Tobeña A, Pekny M, Johansson B. Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. The European Journal of Neuroscience. 16: 547-50. PMID 12193199 DOI: 10.1046/j.1460-9568.2002.02122.x  0.35
2002 Lindskog M, Svenningsson P, Pozzi L, Kim Y, Fienberg AA, Bibb JA, Fredholm BB, Nairn AC, Greengard P, Fisone G. Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature. 418: 774-8. PMID 12181566 DOI: 10.1038/Nature00817  0.703
2002 Lopes LV, Cunha RA, Kull B, Fredholm BB, Ribeiro JA. Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition. Neuroscience. 112: 319-29. PMID 12044450 DOI: 10.1016/S0306-4522(02)00080-5  0.64
2002 Arslan G, Kull B, Fredholm BB. Anoxia redistributes adenosine A(2A) receptors in PC12 cells and increases receptor-mediated formation of cAMP. Naunyn-Schmiedeberg's Archives of Pharmacology. 365: 150-7. PMID 11819033 DOI: 10.1007/s002100100456  0.468
2002 Schulte G, Fredholm BB. Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists. Cellular Signalling. 14: 109-13. PMID 11781134 DOI: 10.1016/S0898-6568(01)00228-5  0.694
2001 Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacological Reviews. 53: 527-52. PMID 11734617  0.381
2001 Brown R, Ollerstam A, Johansson B, Skøtt O, Gebre-Medhin S, Fredholm B, Persson AEG. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 281: R1362-R1367. PMID 11641103 DOI: 10.1152/Ajpregu.2001.281.5.R1362  0.323
2001 Adén U, Leverin AL, Hagberg H, Fredholm BB. Adenosine A(1) receptor agonism in the immature rat brain and heart. European Journal of Pharmacology. 426: 185-92. PMID 11527543 DOI: 10.1016/S0014-2999(01)01220-1  0.426
2001 Johansson B, Halldner L, Dunwiddie TV, Masino SA, Poelchen W, Giménez-Llort L, Escorihuela RM, Fernández-Teruel A, Wiesenfeld-Hallin Z, Xu XJ, HÃ¥rdemark A, Betsholtz C, Herlenius E, Fredholm BB. Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 9407-12. PMID 11470917 DOI: 10.1073/Pnas.161292398  0.35
2001 Basheer R, Halldner L, Alanko L, McCarley RW, Fredholm BB, Porkka-Heiskanen T. Opposite changes in adenosine A1 and A2A receptor mRNA in the rat following sleep deprivation. Neuroreport. 12: 1577-80. PMID 11409719 DOI: 10.1097/00001756-200106130-00013  0.443
2001 Fredholm BB, Irenius E, Kull B, Schulte G. Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochemical Pharmacology. 61: 443-8. PMID 11226378 DOI: 10.1016/S0006-2952(00)00570-0  0.712
2001 Fredholm BB, Arslan G, Halldner L, Kull B, Schulte G, Ådén U, Svenningsson P. Adenosine receptor signaling in vitro and in vivo Drug Development Research. 52: 274-282. DOI: 10.1002/Ddr.1124  0.764
2000 Pintor J, Miras-Portugal T, Fredholm BB. Research on purines and their receptors comes of age. Trends in Pharmacological Sciences. 21: 453-6. PMID 11229416 DOI: 10.1016/S0165-6147(00)01566-2  0.444
2000 Fredholm BB, Arslan G, Halldner L, Kull B, Schulte G, Wasserman W. Structure and function of adenosine receptors and their genes. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 364-74. PMID 11111830 DOI: 10.1007/S002100000313  0.705
2000 Halldner L, Lozza G, Lindström K, Fredholm BB. Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist. European Journal of Pharmacology. 406: 345-54. PMID 11040341 DOI: 10.1016/S0014-2999(00)00682-8  0.468
2000 Arslan G, Fredholm BB. Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells. Neuroscience Letters. 292: 183-6. PMID 11018307 DOI: 10.1016/S0304-3940(00)01461-0  0.437
2000 Kull B, Svenningsson P, Fredholm BB. Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum. Molecular Pharmacology. 58: 771-7. PMID 10999947 DOI: 10.1124/Mol.58.4.771  0.574
2000 Kull B, Svenningsson P, Hall H, Fredholm BB. GTP differentially affects antagonist radioligand binding to adenosine A(1) and A(2A) receptors in human brain. Neuropharmacology. 39: 2374-80. PMID 10974321 DOI: 10.1016/S0028-3908(00)00081-2  0.612
2000 Schulte G, Fredholm BB. Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. Molecular Pharmacology. 58: 477-82. PMID 10953039  0.396
2000 Zahniser NR, Simosky JK, Mayfield RD, Negri CA, Hanania T, Larson GA, Kelly MA, Grandy DK, Rubinstein M, Low MJ, Fredholm BB. Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5949-57. PMID 10934242 DOI: 10.1523/Jneurosci.20-16-05949.2000  0.345
2000 Adén U, Herlenius E, Tang LQ, Fredholm BB. Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain. Pediatric Research. 48: 177-83. PMID 10926292 DOI: 10.1203/00006450-200008000-00010  0.465
2000 Svenningsson P, Fredholm BB, Bloch B, Le Moine C. Co-stimulation of D(1)/D(5) and D(2) dopamine receptors leads to an increase in c-fos messenger RNA in cholinergic interneurons and a redistribution of c-fos messenger RNA in striatal projection neurons. Neuroscience. 98: 749-57. PMID 10891618 DOI: 10.1016/S0306-4522(00)00155-X  0.439
2000 Broad RM, Fallahi N, Fredholm BB. Nitric oxide interacts with oxygen free radicals to evoke the release of adenosine and adenine nucleotides from rat hippocampal slices. Journal of the Autonomic Nervous System. 81: 82-6. PMID 10869705 DOI: 10.1016/S0165-1838(00)00124-7  0.366
2000 Svenningsson P, Fienberg AA, Allen PB, Moine CL, Lindskog M, Fisone G, Greengard P, Fredholm BB. Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32. Journal of Neurochemistry. 75: 248-57. PMID 10854268 DOI: 10.1046/J.1471-4159.2000.0750248.X  0.688
2000 Vainio M, Fredholm BB, Törnquist K. Thyrotropin regulates adenosine A(1) receptor expression in rat thyroid FRTL-5 cells. British Journal of Pharmacology. 130: 471-7. PMID 10807688 DOI: 10.1038/sj.bjp.0703325  0.46
2000 Arslan G, Filipeanu CM, Irenius E, Kull B, Clementi E, Allgaier C, Erlinge D, Fredholm BB. P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells. Neuropharmacology. 39: 482-96. PMID 10698014 DOI: 10.1016/S0028-3908(99)00141-0  0.379
2000 Svenningsson P, Lindskog M, Ledent C, Parmentier M, Greengard P, Fredholm BB, Fisone G. Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 1856-60. PMID 10677546 DOI: 10.1073/Pnas.97.4.1856  0.712
2000 Schulte G, Fredholm BB. Human Adenosine A1, A2A, A2B, and A3 Receptors Expressed in Chinese Hamster Ovary Cells All Mediate the Phosphorylation of Extracellular-Regulated Kinase 1/2 Molecular Pharmacology. 58: 477-482. DOI: 10.1124/Mol.58.3.477  0.716
1999 Arslan G, Fredholm BB. Adenosine and P2 receptors in PC12 cells. Genotypic, phenotypic and individual differences. Progress in Brain Research. 120: 301-10. PMID 10551006 DOI: 10.1016/S0079-6123(08)63564-5  0.356
1999 Fredholm BB, Lindström K. Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors. European Journal of Pharmacology. 380: 197-202. PMID 10513579 DOI: 10.1016/S0014-2999(99)00533-6  0.487
1999 Kull B, Ferré S, Arslan G, Svenningsson P, Fuxe K, Owman C, Fredholm BB. Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors. Biochemical Pharmacology. 58: 1035-45. PMID 10509756 DOI: 10.1016/S0006-2952(99)00184-7  0.725
1999 Svenningsson P, Le Moine C, Fisone G, Fredholm BB. Distribution, biochemistry and function of striatal adenosine A2A receptors. Progress in Neurobiology. 59: 355-96. PMID 10501634 DOI: 10.1016/S0301-0082(99)00011-8  0.567
1999 Lillrank SM, Lipska BK, Weinberger DR, Fredholm BB, Fuxe K, Ferré S. Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus. Neurochemistry International. 34: 235-44. PMID 10355490 DOI: 10.1016/S0197-0186(99)00008-X  0.624
1999 Lindskog M, Svenningsson P, Fredholm B, Greengard P, Fisone G. Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons. The European Journal of Neuroscience. 11: 2182-6. PMID 10336688 DOI: 10.1046/J.1460-9568.1999.00597.X  0.709
1999 Lindskog M, Svenningsson P, Fredholm BB, Greengard P, Fisone G. Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms. Neuroscience. 88: 1005-8. PMID 10336115 DOI: 10.1016/S0306-4522(98)00411-4  0.692
1999 Svenningsson P, Nomikos GG, Fredholm BB. The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4011-22. PMID 10234030 DOI: 10.1523/Jneurosci.19-10-04011.1999  0.562
1999 Svenningsson P, Fourreau L, Bloch B, Fredholm BB, Gonon F, Le Moine C. Opposite tonic modulation of dopamine and adenosine on c-fos gene expression in striatopallidal neurons. Neuroscience. 89: 827-37. PMID 10199616 DOI: 10.1016/S0306-4522(98)00403-5  0.504
1999 Arslan G, Kull B, Fredholm BB. Signaling via A2A adenosine receptor in four PC12 cell clones. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 28-32. PMID 9933147 DOI: 10.1007/Pl00005319  0.483
1999 Ongini E, Dionisotti S, Gessi S, Irenius E, Fredholm BB. Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 7-10. PMID 9933143 DOI: 10.1007/Pl00005326  0.467
1999 Kull B, Arslan G, Nilsson C, Owman C, Lorenzen A, Schwabe U, Fredholm BB. Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical Pharmacology. 57: 65-75. PMID 9920286 DOI: 10.1016/S0006-2952(98)00298-6  0.47
1998 Köhler M, Norgren S, Berggren PO, Fredholm BB, Larsson O, Rhodes CJ, Herbert TP, Luthman H. Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells. Febs Letters. 441: 97-102. PMID 9877173 DOI: 10.1016/S0014-5793(98)01539-7  0.661
1998 Svenningsson P, Le Moine C, Aubert I, Burbaud P, Fredholm BB, Bloch B. Cellular distribution of adenosine A2A receptor mRNA in the primate striatum. The Journal of Comparative Neurology. 399: 229-40. PMID 9721905 DOI: 10.1002/(SICI)1096-9861(19980921)399:2<229::AID-CNE6>3.0.CO;2-2  0.573
1998 Daly JW, Fredholm BB. Caffeine--an atypical drug of dependence. Drug and Alcohol Dependence. 51: 199-206. PMID 9716941 DOI: 10.1016/S0376-8716(98)00077-5  0.378
1998 Svenningsson P, NergÃ¥rdh R, Fredholm BB. Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat. Neuropharmacology. 37: 331-7. PMID 9681931 DOI: 10.1016/S0028-3908(98)00045-8  0.507
1998 Fredholm BB, Johansson B, Lindström K, Wahlström G. Age-dependent changes in adenosine receptors are not modified by life-long intermittent alcohol administration. Brain Research. 791: 177-85. PMID 9593882 DOI: 10.1016/S0006-8993(98)00090-0  0.447
1998 Fredholm BB, Svenningsson P. Striatal adenosine A2A receptors--where are they? What do they do? Trends in Pharmacological Sciences. 19: 46-8. PMID 9550940 DOI: 10.1016/S0165-6147(97)01160-7  0.611
1998 Svenningsson P, Lindskog M, Rognoni F, Fredholm BB, Greengard P, Fisone G. Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons. Neuroscience. 84: 223-8. PMID 9522376 DOI: 10.1016/S0306-4522(97)00510-1  0.719
1998 Fredholm BB, Lindström K, Dionisotti S, Ongini E. [3H]SCH 58261, a selective adenosine A2A receptor antagonist, is a useful ligand in autoradiographic studies. Journal of Neurochemistry. 70: 1210-6. PMID 9489743 DOI: 10.1046/J.1471-4159.1998.70031210.X  0.465
1998 Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB, Fuxe K. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. The Journal of Biological Chemistry. 273: 4718-24. PMID 9468534 DOI: 10.1074/Jbc.273.8.4718  0.721
1998 Klotz KN, Hessling J, Hegler J, Owman C, Kull B, Fredholm BB, Lohse MJ. Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 357: 1-9. PMID 9459566 DOI: 10.1007/Pl00005131  0.504
1998 Fredholm BB, Arslan G, Kuli B, Svenningsson P. Locating the neuronal targets for caffeine Drug Development Research. 45: 324-328. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<324::Aid-Ddr31>3.0.Co;2-1  0.617
1997 Jin S, Fredholm BB. Glucose deprivation increases basal and electrically evoked transmitter release from rat striatal slices. Role of NMDA and adenosine A1 receptors. European Journal of Pharmacology. 340: 169-75. PMID 9537811 DOI: 10.1016/S0014-2999(97)01437-4  0.444
1997 Chergui K, Svenningsson P, Nomikos GG, Gonon F, Fredholm BB, Svennson TH. Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle. The European Journal of Neuroscience. 9: 2370-82. PMID 9464931 DOI: 10.1111/J.1460-9568.1997.Tb01654.X  0.55
1997 Svenningsson P, Georgieva J, Kontny E, Heilig M, Fredholm BB. Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum. The European Journal of Neuroscience. 9: 2135-41. PMID 9421173 DOI: 10.1111/J.1460-9568.1997.Tb01380.X  0.484
1997 Svenningsson P, Hall H, Sedvall G, Fredholm BB. Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study. Synapse (New York, N.Y.). 27: 322-35. PMID 9372555 DOI: 10.1002/(SICI)1098-2396(199712)27:4<322::AID-SYN6>3.0.CO;2-E  0.686
1997 Kvanta A, Seregard S, Sejersen S, Kull B, Fredholm BB. Localization of adenosine receptor messenger RNAs in the rat eye. Experimental Eye Research. 65: 595-602. PMID 9367639 DOI: 10.1006/exer.1996.0352  0.398
1997 Bona E, Adén U, Gilland E, Fredholm BB, Hagberg H. Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists. Neuropharmacology. 36: 1327-38. PMID 9364488 DOI: 10.1016/S0028-3908(97)00139-1  0.397
1997 Arslan G, Kontny E, Fredholm BB. Down-regulation of adenosine A2A receptors upon NGF-induced differentiation of PC12 cells. Neuropharmacology. 36: 1319-26. PMID 9364487 DOI: 10.1016/S0028-3908(97)00090-7  0.49
1997 Svenningsson P, Fredholm BB. Caffeine mimics the effect of a dopamine D2/3 receptor agonist on the expression of immediate early genes in globus pallidus. Neuropharmacology. 36: 1309-17. PMID 9364486 DOI: 10.1016/S0028-3908(97)00091-9  0.576
1997 Ferré S, Fredholm BB, Morelli M, Popoli P, Fuxe K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends in Neurosciences. 20: 482-7. PMID 9347617 DOI: 10.1016/S0166-2236(97)01096-5  0.637
1997 Le Moine C, Svenningsson P, Fredholm BB, Bloch B. Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8038-48. PMID 9315922 DOI: 10.1523/Jneurosci.17-20-08038.1997  0.559
1997 Johansson B, Georgiev V, Fredholm BB. Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with dopamine receptors. Neuroscience. 80: 1187-207. PMID 9284070  0.318
1997 Svenningsson P, Le Moine C, Kull B, Sunahara R, Bloch B, Fredholm BB. Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience. 80: 1171-85. PMID 9284069 DOI: 10.1016/S0306-4522(97)00180-2  0.549
1997 Johansson B, Georgiev V, Lindström K, Fredholm BB. A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment. Brain Research. 762: 153-64. PMID 9262169 DOI: 10.1016/S0006-8993(97)00378-8  0.447
1997 Jin S, Fredholm BB. Electrically-evoked dopamine and acetylcholine release from rat striatal slices perfused without magnesium: regulation by glutamate acting on NMDA receptors. British Journal of Pharmacology. 121: 1269-76. PMID 9257903 DOI: 10.1038/sj.bjp.0701267  0.418
1997 Jin S, Fredholm BB. Adenosine A1 receptors mediate hypoxia-induced inhibition of electrically evoked transmitter release from rat striatal slices. European Journal of Pharmacology. 329: 107-13. PMID 9226401 DOI: 10.1016/S0014-2999(97)89172-8  0.433
1997 Svenningsson P, Nomikos GG, Ongini E, Fredholm BB. Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens. Neuroscience. 79: 753-64. PMID 9219939 DOI: 10.1016/S0306-4522(97)00046-8  0.558
1997 Dionisotti S, Ongini E, Zocchi C, Kull B, Arslan G, Fredholm BB. Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. British Journal of Pharmacology. 121: 353-60. PMID 9179373 DOI: 10.1038/sj.bjp.0701119  0.465
1997 Fredholm BB, Abbracchio MP, Burnstock G, Dubyak GR, Harden TK, Jacobson KA, Schwabe U, Williams M. Towards a revised nomenclature for P1 and P2 receptors. Trends in Pharmacological Sciences. 18: 79-82. PMID 9133776 DOI: 10.1016/S0165-6147(96)01038-3  0.527
1997 Stone-Elander S, Thorell JO, Eriksson L, Fredholm BB, Ingvar M. In vivo biodistribution of [N-11C-methyl]KF 17837 using 3-D-PET: evaluation as a ligand for the study of adenosine A2A receptors. Nuclear Medicine and Biology. 24: 187-91. PMID 9089711 DOI: 10.1016/S0969-8051(96)00216-8  0.339
1997 Fredholm BB. Purines and neutrophil leukocytes. General Pharmacology. 28: 345-50. PMID 9068971 DOI: 10.1016/S0306-3623(96)00169-3  0.444
1997 Kontny E, Ciruela F, Svenningsson P, Ibáñez CF, Fredholm BB. On the role of the low-affinity neurotrophin receptor p75LNTR in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells. Journal of Molecular Neuroscience : Mn. 8: 29-44. PMID 9061613 DOI: 10.1007/Bf02736861  0.636
1997 Svenningsson P, Fredholm BB. Glucocorticoids regulate the expression of adenosine A1 but not A(2A) receptors in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 280: 1094-101. PMID 9023328  0.57
1997 Jin S, Fredholm BB. Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release. Naunyn-Schmiedeberg's Archives of Pharmacology. 355: 48-56. PMID 9007842 DOI: 10.1007/Pl00004917  0.442
1997 Bona E, Ådén U, Gilland E, Fredholm BB, Hagberg H. The Effect of Adenosine Receptor Antagonists on Neonatal Cerebral Hypoxia-Ischemia Pediatric Research. 42: 386-386. DOI: 10.1203/00006450-199709000-00030  0.387
1996 Johansson B, Georgiev V, Kuosmanen T, Fredholm BB. Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. The European Journal of Neuroscience. 8: 2447-58. PMID 8996794 DOI: 10.1111/J.1460-9568.1996.Tb01539.X  0.361
1996 Dasgupta S, Ferré S, Kull B, Hedlund PB, Finnman UB, Ahlberg S, Arenas E, Fredholm BB, Fuxe K. Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells. European Journal of Pharmacology. 316: 325-31. PMID 8982704 DOI: 10.1016/S0014-2999(96)00665-6  0.718
1996 Ongini E, Fredholm BB. Pharmacology of adenosine A2A receptors. Trends in Pharmacological Sciences. 17: 364-72. PMID 8979771 DOI: 10.1016/S0165-6147(96)80010-1  0.49
1996 Jacobson KA, von Lubitz DK, Daly JW, Fredholm BB. Adenosine receptor ligands: differences with acute versus chronic treatment. Trends in Pharmacological Sciences. 17: 108-13. PMID 8936347 DOI: 10.1016/0165-6147(96)10002-X  0.541
1996 Zhang Y, Raud J, Hedqvist P, Fredholm BB. Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A2A receptors. European Journal of Pharmacology. 313: 237-42. PMID 8911920 DOI: 10.1016/0014-2999(96)00523-7  0.491
1996 Lindström K, Ongini E, Fredholm BB. The selective adenosine A2A receptor antagonist SCH 58261 discriminates between two different binding sites for [3H]-CGS 21680 in the rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 354: 539-41. PMID 8897460  0.317
1996 Fredholm BB, Wallman-Johansson A. Effects of ethanol and acetate on adenosine production in rat hippocampal slices. Pharmacology & Toxicology. 79: 120-3. PMID 8884869 DOI: 10.1111/J.1600-0773.1996.Tb00254.X  0.325
1996 Fredholm BB, Zhang Y, van der Ploeg I. Adenosine A2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes. Naunyn-Schmiedeberg's Archives of Pharmacology. 354: 262-7. PMID 8878055  0.422
1996 Sipma H, Fredholm BB, Den Hertog A, Nelemans A. Plasma membrane Ca2+ pumping plays a prominent role in adenosine A1 receptor mediated changes in [Ca2+]i in DDT1 MF-2 cells. European Journal of Pharmacology. 306: 187-94. PMID 8813632 DOI: 10.1016/0014-2999(96)00183-5  0.333
1996 Ferre S, O'Connor WT, Svenningsson P, Bjorklund L, Lindberg J, Tinner B, Stromberg I, Goldstein M, Ogren SO, Ungerstedt U, Fredholm BB, Fuxe K. Dopamine D1 receptor-mediated facilitation of GABAergic neurotransmission in the rat strioentopenduncular pathway and its modulation by adenosine A1 receptor-mediated mechanisms. The European Journal of Neuroscience. 8: 1545-53. PMID 8758962 DOI: 10.1111/J.1460-9568.1996.Tb01617.X  0.787
1996 Jiang S, Kull B, Fredholm BB, Orrenius S. P2x purinoceptor is not important in thymocyte apoptosis. Immunology Letters. 49: 197-201. PMID 8739317 DOI: 10.1016/0165-2478(96)02507-2  0.328
1996 Svenningsson P, Johansson B, Fredholm BB. Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801. Brain Research. Molecular Brain Research. 35: 183-9. PMID 8717354 DOI: 10.1016/0169-328X(95)00202-4  0.543
1996 Cunha RA, Johansson B, Constantino MD, Sebastião AM, Fredholm BB. Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 261-71. PMID 8692280 DOI: 10.1007/Bf00168627  0.549
1996 van der Ploeg I, Ahlberg S, Parkinson FE, Olsson RA, Fredholm BB. Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 250-60. PMID 8692279 DOI: 10.1007/BF00168626  0.455
1996 Parkinson FE, Johansson B, Lindström K, Fredholm BB. Adenosine A1 and A2A receptors and nitrobenzylthioinosine-sensitive transporters in gerbil brain: no changes following long-term treatment with the adenosine transport inhibitor propentofylline. Neuropharmacology. 35: 79-89. PMID 8684600 DOI: 10.1016/0028-3908(95)00155-7  0.364
1996 Fallahi N, Broad RM, Jin S, Fredholm BB. Release of adenosine from rat hippocampal slices by nitric oxide donors. Journal of Neurochemistry. 67: 186-93. PMID 8666990 DOI: 10.1046/J.1471-4159.1996.67010186.X  0.363
1996 Zhang Y, Palmblad J, Fredholm BB. Biphasic effect of ATP on neutrophil functions mediated by P2U and adenosine A2A receptors. Biochemical Pharmacology. 51: 957-65. PMID 8651946 DOI: 10.1016/0006-2952(95)02403-4  0.406
1996 Fernandez M, Svenningsson P, Fredholm BB. Adaptive changes in adenosine receptors following long-term treatment with the adenosine receptor agonist R-phenylisopropyl adenosine. Life Sciences. 58: 769-76. PMID 8632724 DOI: 10.1016/0024-3205(95)02355-0  0.623
1996 Broad RM, Fredholm BB. A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex. The Journal of Pharmacology and Experimental Therapeutics. 277: 193-7. PMID 8613918  0.323
1996 Fredholm BB. Chapter 11 Adenosine and Neuroprotection International Review of Neurobiology. 40: 259-280. DOI: 10.1016/S0074-7742(08)60723-0  0.407
1996 Ongini E, Dionisotti S, Morelli M, Ferr� S, Svenningsson P, Fuxe K, Fredholm BB. Neuropharmacology of the adenosine A2A receptors Drug Development Research. 39: 450-460. DOI: 10.1002/(SICI)1098-2299(199611/12)39:3/4<450::AID-DDR27>3.0.CO;2-3  0.708
1996 Fredholm BB, Arslan G, Kull B, Kontny E, Svenningsson P. Adenosine (P1) receptor signalling Drug Development Research. 39: 262-268. DOI: 10.1002/(SICI)1098-2299(199611/12)39:3/4<262::AID-DDR5>3.0.CO;2-P  0.548
1995 Gerwins P, Fredholm BB. Activation of phospholipase C and phospholipase D by stimulation of adenosine A1, bradykinin or P2U receptors does not correlate well with protein kinase C activation. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 194-201. PMID 7770101 DOI: 10.1007/Bf00169333  0.477
1995 Gerwins P, Fredholm BB. Activation of adenosine A1 and bradykinin receptors increases protein kinase C and phospholipase D activity in smooth muscle cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 186-93. PMID 7770100 DOI: 10.1007/Bf00169332  0.473
1995 Svenningsson P, Ström A, Johansson B, Fredholm BB. Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3583-93. PMID 7751931 DOI: 10.1523/Jneurosci.15-05-03583.1995  0.41
1995 Fredholm BB. Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine. Pharmacology & Toxicology. 76: 93-101. PMID 7746802 DOI: 10.1111/J.1600-0773.1995.Tb00111.X  0.496
1995 Lloyd HG, Fredholm BB. Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices. Neurochemistry International. 26: 387-95. PMID 7633332 DOI: 10.1016/0197-0186(94)00144-J  0.378
1995 Fredholm BB. Purinoceptors in the nervous system. Pharmacology & Toxicology. 76: 228-39. PMID 7617551 DOI: 10.1111/J.1600-0773.1995.Tb00135.X  0.48
1995 Svenningsson P, Johansson B, Fredholm BB. Effect of different xanthines and phosphodiesterase inhibitors on c-fos expression in rat striatum. Acta Physiologica Scandinavica. 154: 17-24. PMID 7572198 DOI: 10.1111/j.1748-1716.1995.tb09881.x  0.463
1995 Johansson B, Fredholm BB. Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography. Neuropharmacology. 34: 393-403. PMID 7566470 DOI: 10.1016/0028-3908(95)00009-U  0.434
1995 Cunha RA, Johansson B, Fredholm BB, Ribeiro JA, Sebastião AM. Adenosine A2A receptors stimulate acetylcholine release from nerve terminals of the rat hippocampus. Neuroscience Letters. 196: 41-4. PMID 7501252 DOI: 10.1016/0304-3940(95)11833-I  0.633
1995 Bona E, Adén U, Fredholm BB, Hagberg H. The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate. Pediatric Research. 38: 312-8. PMID 7494652 DOI: 10.1203/00006450-199509000-00007  0.383
1995 Svenningsson P, Nomikos GG, Fredholm BB. Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7612-24. PMID 7472512 DOI: 10.1523/Jneurosci.15-11-07612.1995  0.535
1995 Hu PS, Fredholm BB. 4-Aminopyridine-induced increase in basal and stimulation-evoked [3H]-NA release in slices from rat hippocampus: Ca2+ sensitivity and presynaptic control. British Journal of Pharmacology. 102: 764-8. PMID 1364850 DOI: 10.1111/j.1476-5381.1991.tb12247.x  0.394
1994 Fredholm BB, Lindström K, Wallman-Johansson A. Propentofylline and other adenosine transport inhibitors increase the efflux of adenosine following electrical or metabolic stimulation of rat hippocampal slices. Journal of Neurochemistry. 62: 563-73. PMID 8294919 DOI: 10.1046/J.1471-4159.1994.62020563.X  0.418
1994 Adén U, Lindström K, Bona E, Hagberg H, Fredholm BB. Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia. Brain Research. Molecular Brain Research. 23: 354-8. PMID 8090076 DOI: 10.1016/0169-328X(94)90247-X  0.449
1994 Wallman-Johansson A, Fredholm BB. Release of adenosine and other purines from hippocampal slices stimulated electrically or by hypoxia/hypoglycemia. Effect of chlormethiazole. Life Sciences. 55: 721-8. PMID 8065235 DOI: 10.1016/0024-3205(94)00680-6  0.366
1994 Cunha RA, Johansson B, van der Ploeg I, Sebastião AM, Ribeiro JA, Fredholm BB. Evidence for functionally important adenosine A2a receptors in the rat hippocampus. Brain Research. 649: 208-16. PMID 7953635 DOI: 10.1016/0006-8993(94)91066-9  0.625
1994 Fredholm BB, Altiok N. Adenosine A2B receptor signalling is altered by stimulation of bradykinin or interleukin receptors in astroglioma cells. Neurochemistry International. 25: 99-102. PMID 7950978 DOI: 10.1016/0197-0186(94)90060-4  0.469
1994 Parkinson FE, Rudolphi KA, Fredholm BB. Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia. General Pharmacology. 25: 1053-8. PMID 7875526 DOI: 10.1016/0306-3623(94)90119-8  0.447
1994 Jin S, Fredholm BB. Role of NMDA, AMPA and kainate receptors in mediating glutamate- and 4-AP-induced dopamine and acetylcholine release from rat striatal slices. Neuropharmacology. 33: 1039-48. PMID 7838316 DOI: 10.1016/0028-3908(94)90141-4  0.336
1994 Snaprud P, Gerwins P, Caron MG, Libert F, Persson H, Fredholm BB, Fuxe K. A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA. Biochemical Pharmacology. 48: 2043-7. PMID 7802693 DOI: 10.1016/0006-2952(94)90503-7  0.637
1994 Zhang Y, Fredholm BB. Propentofylline enhancement of the actions of adenosine on neutrophil leukocytes. Biochemical Pharmacology. 48: 2025-32. PMID 7802691 DOI: 10.1016/0006-2952(94)90501-0  0.5
1994 Schubert P, Rudolphi KA, Fredholm BB, Nakamura Y. Modulation of nerve and glial function by adenosine--role in the development of ischemic damage. The International Journal of Biochemistry. 26: 1227-36. PMID 7531656 DOI: 10.1016/0020-711X(94)90092-2  0.479
1993 Johansson B, Ahlberg S, van der Ploeg I, Brené S, Lindefors N, Persson H, Fredholm BB. Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 347: 407-14. PMID 8510768 DOI: 10.1007/Bf00165391  0.435
1993 Ljunggren O, Fredholm BB, Nordstedt C, Ljunghall S, Lerner UH. Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts. European Journal of Pharmacology. 244: 111-7. PMID 8432308 DOI: 10.1016/0922-4106(93)90015-2  0.744
1993 Fredholm BB, Gerwins P, Johansson B, Parkinson FE, van der Ploeg I. Signalling via G-protein coupled receptors--using adenosine receptors as an example. Drug Design and Discovery. 9: 189-97. PMID 8400002  0.31
1993 Agnati LF, Fuxe K, Benfenati F, von Euler G, Fredholm B. Intramembrane receptor-receptor interactions: integration of signal transduction pathways in the nervous system. Neurochemistry International. 22: 213-22. PMID 8382983 DOI: 10.1016/0197-0186(93)90049-B  0.628
1993 Lloyd HG, Lindström K, Fredholm BB. Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion. Neurochemistry International. 23: 173-85. PMID 8369741 DOI: 10.1016/0197-0186(93)90095-M  0.375
1993 Georgiev V, Johansson B, Fredholm BB. Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number. Brain Research. 612: 271-7. PMID 8330205 DOI: 10.1016/0006-8993(93)91672-F  0.361
1993 Johansson B, Georgiev V, Parkinson FE, Fredholm BB. The binding of the adenosine A2 receptor selective agonist [3H]CGS 21680 to rat cortex differs from its binding to rat striatum. European Journal of Pharmacology. 247: 103-10. PMID 8281998 DOI: 10.1016/0922-4106(93)90066-I  0.373
1993 Dunér-Engström M, Fredholm BB. Breakdown of membrane choline-phospholipids induced by endogenous and exogenous muscarinic agonist is potentiated by VIP in rat submandibular gland. Acta Physiologica Scandinavica. 149: 41-9. PMID 8237421 DOI: 10.1111/j.1748-1716.1993.tb09590.x  0.318
1993 Fredholm BB, Hu PS. Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices. British Journal of Pharmacology. 108: 126-31. PMID 8094021 DOI: 10.1111/J.1476-5381.1993.Tb13451.X  0.408
1993 Kvanta A, Fredholm BB. Synergistic effects between protein kinase C and cAMP on activator protein-1 activity and differentiation of PC-12 pheochromocytoma cells. Journal of Molecular Neuroscience : Mn. 4: 205-14. PMID 7917831 DOI: 10.1007/BF02821552  0.336
1993 Jin S, Johansson B, Fredholm BB. Effects of adenosine A1 and A2 receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices. The Journal of Pharmacology and Experimental Therapeutics. 267: 801-8. PMID 7902434  0.351
1993 Altiok N, Fredholm BB. Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase. Cellular Signalling. 5: 279-88. PMID 7688545 DOI: 10.1016/0898-6568(93)90018-H  0.341
1993 Fredholm BB, Johansson B, van der Ploeg I, Hu PS, Jin S. Neuromodulatory roles of purines Drug Development Research. 28: 349-353. DOI: 10.1002/ddr.430280329  0.486
1993 Abbracchio MP, Cattabeni F, Fredholm BB, Williams M. Purinoceptor nomenclature: A status report Drug Development Research. 28: 207-213. DOI: 10.1002/DDR.430280304  0.454
1992 Parkinson FE, Fredholm BB. Magnesium-dependent enhancement of endogenous agonist binding to A1 adenosine receptors: a complicating factor in quantitative autoradiography. Journal of Neurochemistry. 58: 941-50. PMID 1738001 DOI: 10.1111/J.1471-4159.1992.Tb09347.X  0.419
1992 Fredholm BB, Fastbom J, Kvanta A, Gerwins P, Parkinson F. Further evidence that propentofylline (HWA 285) influences both adenosine receptors and adenosine transport. Fundamental & Clinical Pharmacology. 6: 99-111. PMID 1628877 DOI: 10.1111/J.1472-8206.1992.Tb00101.X  0.493
1992 van der Ploeg I, Parkinson FE, Fredholm BB. Effect of pertussis toxin on radioligand binding to rat brain adenosine A1 receptors. Journal of Neurochemistry. 58: 1221-9. PMID 1548460 DOI: 10.1111/J.1471-4159.1992.Tb11332.X  0.466
1992 Kvanta A, Kontny E, Jondal M, Okret S, Fredholm BB. Mitogen stimulation of T-cells increases c-Fos and c-Jun protein levels, AP-1 binding and AP-1 transcriptional activity. Cellular Signalling. 4: 275-86. PMID 1510878 DOI: 10.1016/0898-6568(92)90067-I  0.327
1992 Johansson B, Svenningsson P, Adén U, Lindström K, Fredholm BB. Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors. Acta Physiologica Scandinavica. 146: 539-41. PMID 1492572 DOI: 10.1111/j.1748-1716.1992.tb09461.x  0.499
1992 Ferré S, Fuxe K, von Euler G, Johansson B, Fredholm BB. Adenosine-dopamine interactions in the brain. Neuroscience. 51: 501-12. PMID 1488111 DOI: 10.1016/0306-4522(92)90291-9  0.517
1992 Rudolphi KA, Schubert P, Parkinson FE, Fredholm BB. Adenosine and brain ischemia. Cerebrovascular and Brain Metabolism Reviews. 4: 346-69. PMID 1486019  0.36
1992 Johansson B, Parkinson FE, Fredholm BB. Effects of mono- and divalent ions on the binding of the adenosine analogue CGS 21680 to adenosine A2 receptors in rat striatum. Biochemical Pharmacology. 44: 2365-70. PMID 1472101 DOI: 10.1016/0006-2952(92)90681-8  0.334
1992 Meana JJ, Johansson B, Herrera-Marschitz M, O'Connor WT, Goiny M, Parkinson FE, Fredholm BB, Ungerstedt U. Effect of the neurotoxin AF64A on intrinsic and extrinsic neuronal systems of rat neostriatum measured by in vivo microdialysis. Brain Research. 596: 65-72. PMID 1361419 DOI: 10.1016/0006-8993(92)91533-K  0.601
1992 Dunér-Engström M, Larsson O, Fredholm BB, Lundblad L, Fahrenkrug J, Lundberg JM. Effects of acute and long-term atropine treatment on levels, release and response to VIP and PHI in the submandibular gland of cat and rat. Acta Physiologica Scandinavica. 146: 357-67. PMID 1336298 DOI: 10.1111/J.1748-1716.1992.Tb09430.X  0.692
1992 Kontny E, Kvanta A, Fredholm BB. Activation of protein kinase C and elevation of cAMP interact synergistically to raise c-Fos and AP-1 activity in Jurkat cells. European Journal of Pharmacology. 227: 333-8. PMID 1335418 DOI: 10.1016/0922-4106(92)90012-K  0.402
1992 Balmforth AJ, Parkinson FE, Altiok N, Fredholm BB. Identification of a B2-bradykinin receptor linked to phospholipase C and inhibition of dopamine stimulated cyclic AMP accumulation in the human astrocytoma cell line D384. Naunyn-Schmiedeberg's Archives of Pharmacology. 346: 303-10. PMID 1328896 DOI: 10.1007/BF00173543  0.441
1992 Gerwins P, Fredholm BB. Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 7330-4. PMID 1323831 DOI: 10.1073/Pnas.89.16.7330  0.488
1992 Gerwins P, Fredholm BB. ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line. The Journal of Biological Chemistry. 267: 16081-7. PMID 1322890  0.337
1992 Altiok N, Balmforth AJ, Fredholm BB. Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon. Acta Physiologica Scandinavica. 144: 55-63. PMID 1317654 DOI: 10.1111/j.1748-1716.1992.tb09267.x  0.407
1992 Rudolphi KA, Schubert P, Parkinson FE, Fredholm BB. Neuroprotective role of adenosine in cerebral ischaemia. Trends in Pharmacological Sciences. 13: 439-45. PMID 1293870 DOI: 10.1016/0165-6147(92)90141-R  0.385
1992 Altiok N, Fredholm BB. Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP. Neurochemistry International. 21: 209-13. PMID 1284620 DOI: 10.1016/0197-0186(92)90149-L  0.391
1992 Fredholm B, Hu P. Autoreceptor and adenosine A1 receptor-regulation of noradrenaline release in the rat hippocampus Neurochemistry International. 21: Q7. DOI: 10.1016/0197-0186(92)91812-B  0.329
1991 Fredholm BB. Adenosine A1-receptor-mediated inhibition of evoked acetylcholine release in the rat hippocampus does not depend on protein kinase C. Acta Physiologica Scandinavica. 140: 245-55. PMID 2267953 DOI: 10.1111/J.1748-1716.1990.TB08996.X  0.359
1991 Kvanta A, Gerwins P, Jondal M, Fredholm BB. Stimulation of T-cells with OKT3 antibodies increases forskolin binding and cyclic AMP accumulation. Cellular Signalling. 2: 461-70. PMID 2177619 DOI: 10.1016/0898-6568(90)90042-9  0.422
1991 von Euler G, van der Ploeg I, Fredholm BB, Fuxe K. Neurotensin decreases the affinity of dopamine D2 agonist binding by a G protein-independent mechanism. Journal of Neurochemistry. 56: 178-83. PMID 1824779 DOI: 10.1111/J.1471-4159.1991.Tb02578.X  0.554
1991 van der Ploeg I, Cintra A, Altiok N, Askelöf P, Fuxe K, Fredholm BB. Limited distribution of pertussis toxin in rat brain after injection into the lateral cerebral ventricles. Neuroscience. 44: 205-14. PMID 1770997 DOI: 10.1016/0306-4522(91)90261-L  0.459
1991 Parkinson FE, Fredholm BB. Effects of propentofylline on adenosine A1 and A2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: quantitative autoradiographic analysis. European Journal of Pharmacology. 202: 361-6. PMID 1748157 DOI: 10.1016/0014-2999(91)90279-Y  0.432
1991 Hu PS, Benishin C, Fredholm BB. Comparison of the effects of four dendrotoxin peptides, 4-aminopyridine and tetraethylammonium on the electrically evoked [3H]noradrenaline release from rat hippocampus. European Journal of Pharmacology. 209: 87-93. PMID 1687682 DOI: 10.1016/0014-2999(91)90015-I  0.347
1991 Ferre S, von Euler G, Johansson B, Fredholm BB, Fuxe K. Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proceedings of the National Academy of Sciences of the United States of America. 88: 7238-41. PMID 1678519 DOI: 10.1073/Pnas.88.16.7238  0.646
1991 Kvanta A, Jondal M, Fredholm BB. CD3-dependent increase in cyclic AMP in human T-cells following stimulation of the CD2 receptor. Biochimica Et Biophysica Acta. 1093: 178-83. PMID 1677813 DOI: 10.1016/0167-4889(91)90120-M  0.344
1991 van der Ploeg I, Altiok N, Kvanta A, Nordstedt C, Fredholm BB. Role of a pertussis toxin sensitive G-protein in mediating the effects of phorbol esters on receptor activated cyclic AMP accumulation in Jurkat cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 344: 611-7. PMID 1667331 DOI: 10.1007/Bf00170660  0.776
1991 Gerwins P, Fredholm BB. Glucocorticoid receptor activation leads to up-regulation of adenosine A1 receptors and down-regulation of adenosine A2 responses in DDT1 MF-2 smooth muscle cells. Molecular Pharmacology. 40: 149-55. PMID 1652051  0.413
1991 Gerwins P, Nordstedt C, Fredholm BB. GTP and IAP Shifts Adenosine A1-Agonist Binding in Smooth Muscle Membranes to the Low Affinity State, Similar to the one Found in Intact Cells Nucleosides and Nucleotides. 10: 1173-1174. DOI: 10.1080/07328319108047264  0.341
1991 Parkinson FE, Johansson B, Fredholm BB, Rudolphi K. Autoradiographical studies of in vitro and chronic in vivo effects of propentofylline on adenosine a1AND A2, receptors and nbmpr-sensitive nucleoside transporters Nucleosides and Nucleotides. 10: 1145-1147. DOI: 10.1080/07328319108047257  0.345
1991 Fredholm BB, Gerwins P, Hu PS, Der Ploeg IV, Parkinson F, Ballarin M. Pharmacological implications of a multiplicity of adenosine actions in the cns Nucleosides and Nucleotides. 10: 955-964. DOI: 10.1080/07328319108047233  0.403
1991 Fredholm B. Adenosine and adenosine receptors Trends in Pharmacological Sciences. 12: 76. DOI: 10.1016/0165-6147(91)90503-K  0.474
1990 Fredholm BB, Dunér-Engström M. Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus. Pharmacology & Toxicology. 65: 347-51. PMID 2560182 DOI: 10.1111/J.1600-0773.1989.TB01186.X  0.504
1990 Dux E, Fastbom J, Ungerstedt U, Rudolphi K, Fredholm BB. Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus. Brain Research. 516: 248-56. PMID 2364291 DOI: 10.1016/0006-8993(90)90925-2  0.655
1990 Kvanta A, Nordstedt C, Fredholm B, Gullberg M, Jondal M. Evidence that protein kinase C activation is essential for killing by IL-2-activated lymphocytes. Scandinavian Journal of Immunology. 31: 103-8. PMID 2300789 DOI: 10.1111/J.1365-3083.1990.Tb02748.X  0.707
1990 Andiné P, Rudolphi KA, Fredholm BB, Hagberg H. Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. British Journal of Pharmacology. 100: 814-8. PMID 2207501 DOI: 10.1111/j.1476-5381.1990.tb14097.x  0.347
1990 Nordstedt C, Fredholm BB. A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid. Analytical Biochemistry. 189: 231-4. PMID 2177960 DOI: 10.1016/0003-2697(90)90113-N  0.704
1990 Fredholm BB. Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus. Journal of Neurochemistry. 54: 1386-90. PMID 2156020 DOI: 10.1111/j.1471-4159.1990.tb01973.x  0.459
1990 Fastbom J, Fredholm BB. Effects of long-term theophylline treatment on adenosine A1-receptors in rat brain: autoradiographic evidence for increased receptor number and altered coupling to G-proteins. Brain Research. 507: 195-9. PMID 2110844 DOI: 10.1016/0006-8993(90)90272-D  0.44
1990 Kvanta A, Gerwins P, van der Ploeg I, Nordstedt C, Jondal M, Fredholm BB. Stimulation of the T-cell receptors CD3 and CD2 with OKT3 and OKT11 antibodies activates a common pertussis toxin-insensitive G-protein. European Journal of Pharmacology. 189: 363-72. PMID 1981560 DOI: 10.1016/0922-4106(90)90033-T  0.709
1990 Parkinson FE, Fredholm BB. Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand. Naunyn-Schmiedeberg's Archives of Pharmacology. 342: 85-9. PMID 1698265 DOI: 10.1007/BF00178977  0.426
1990 FREDHOLM BB, LLOYD HG. Sources of Adenosine Released from Hippocampal Slices following Electrical and Hypoxic/Hypoglycemic Stimulation Annals of the New York Academy of Sciences. 603: 497-499. DOI: 10.1111/j.1749-6632.1990.tb37718.x  0.315
1989 Larsson O, Fredholm BB. Carbachol stimulation of inositol phosphate accumulation in rat submandibular gland fragments is not modified by VIP. Acta Physiologica Scandinavica. 135: 263-9. PMID 2929366 DOI: 10.1111/J.1748-1716.1989.Tb08576.X  0.689
1989 Rudolphi KA, Keil M, Fastbom J, Fredholm BB. Ischaemic damage in gerbil hippocampus is reduced following upregulation of adenosine (A1) receptors by caffeine treatment. Neuroscience Letters. 103: 275-80. PMID 2812514 DOI: 10.1016/0304-3940(89)90112-2  0.421
1989 Runold M, Lagercrantz H, Prabhakar NR, Fredholm BB. Role of adenosine in hypoxic ventilatory depression. Journal of Applied Physiology (Bethesda, Md. : 1985). 67: 541-6. PMID 2793655 DOI: 10.1152/Jappl.1989.67.2.541  0.303
1989 Kvanta A, Nordstedt C, Jondal M, Fredholm BB. Activation of protein kinase C via the T-cell receptor complex potentiates cyclic AMP responses in T-cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 340: 715-7. PMID 2561306 DOI: 10.1007/Bf00169679  0.75
1989 Von Euler G, Fuxe K, Van der Ploeg I, Fredholm BB, Agnati LF. Pertussis toxin treatment counteracts intramembrane interactions between neuropeptide Y receptors and alpha 2-adrenoceptors. European Journal of Pharmacology. 172: 435-41. PMID 2558898 DOI: 10.1016/0922-4106(89)90026-6  0.574
1989 Fredholm BB, Proctor W, Van der Ploeg I, Dunwiddie TV. In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus. European Journal of Pharmacology. 172: 249-62. PMID 2550263 DOI: 10.1016/0922-4106(89)90055-2  0.468
1989 Nordstedt C, Kvanta A, Van der Ploeg I, Fredholm BB. Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line. European Journal of Pharmacology. 172: 51-60. PMID 2540999 DOI: 10.1016/0922-4106(89)90044-8  0.778
1989 Härfstrand A, Fuxe K, Agnati L, Fredholm B. Reciprocal interactions between α2-adrenoceptor agonist and neuropeptide Y binding sites in the nucleus tractus solitarius of the rat. A biochemic and autoradiographic analysis Journal of Neural Transmission. 75: 83-99. PMID 2537374 DOI: 10.1007/Bf01677422  0.544
1989 Kvanta A, Nordstedt C, van der Ploeg I, Jondal M, Fredholm BB. CD3/T-cell receptor coupling to a pertussis and cholera toxin-insensitive G-protein. Febs Letters. 250: 536-40. PMID 2526752 DOI: 10.1016/0014-5793(89)80791-4  0.734
1989 Fuxe K, von Euler G, van der Ploeg I, Fredholm BB, Agnati LF. Pertussis toxin treatment counteracts the cardiovascular effects of neuropeptide Y and clonidine in the awake unrestrained rat. Neuroscience Letters. 101: 337-41. PMID 2505200 DOI: 10.1016/0304-3940(89)90556-9  0.542
1989 Dunér-Engström M, Fredholm BB. Evidence that prejunctional adenosine receptors regulating acetylcholine release from rat hippocampal slices are linked to an N-ethylmaleimide-sensitive G-protein, but not to adenylate cyclase or dihydropyridine-sensitive Ca2+-channels. Acta Physiologica Scandinavica. 134: 119-26. PMID 2467517 DOI: 10.1111/J.1748-1716.1988.TB08467.X  0.304
1988 Fredholm BB, Dunwiddie TV. How does adenosine inhibit transmitter release? Trends in Pharmacological Sciences. 9: 130-4. PMID 2907698 DOI: 10.1016/0165-6147(88)90194-0  0.409
1988 Nordstedt C, Kvanta A, Fredholm BB. Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization. Biochemical and Biophysical Research Communications. 157: 1046-50. PMID 2849928 DOI: 10.1016/S0006-291X(88)80980-X  0.777
1988 Ng J, Fredholm BB, Jondal M, Andersson T. Regulation of receptor-mediated calcium influx across the plasma membrane in a human leukemic T-cell line: evidence of its dependence on an initial calcium mobilization from intracellular stores. Biochimica Et Biophysica Acta. 971: 207-14. PMID 2844288 DOI: 10.1016/0167-4889(88)90193-0  0.312
1988 Fredholm BB, Lindgren E. Protein kinase C activation increases noradrenaline release from the rat hippocampus and modifies the inhibitory effect of alpha 2-adrenoceptor and adenosine A1-receptor agonists. Naunyn-Schmiedeberg's Archives of Pharmacology. 337: 477-83. PMID 2842695 DOI: 10.1007/BF00182719  0.464
1988 Chow SC, NG J, Nordstedt C, Fredholm BB, Jondal M. Phosphoinositide breakdown and evidence for protein kinase C involvement during human NK killing. Cellular Immunology. 114: 96-103. PMID 2836072 DOI: 10.1016/0008-8749(88)90257-2  0.702
1988 Lundberg JM, Hemsén A, Rudehill A, Härfstrand A, Larsson O, Sollevi A, Saria A, Hökfelt T, Fuxe K, Fredholm BB. Neuropeptide Y- and alpha-adrenergic receptors in pig spleen: localization, binding characteristics, cyclic AMP effects and functional responses in control and denervated animals. Neuroscience. 24: 659-72. PMID 2834666 DOI: 10.1016/0306-4522(88)90359-4  0.611
1988 Lundberg JM, Hemsén A, Larsson O, Rudehill A, Saria A, Fredholm BB. Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction. European Journal of Pharmacology. 145: 21-9. PMID 2832184 DOI: 10.1016/0014-2999(88)90344-5  0.746
1988 Häggblad J, Fredholm BB. Adenosine and neuropeptide Y enhance alpha 1-adrenoceptor-induced accumulation of inositol phosphates and attenuate forskolin-induced accumulation of cyclic AMP in rat vas deferens. Neuroscience Letters. 82: 211-6. PMID 2827073 DOI: 10.1016/0304-3940(87)90132-7  0.373
1987 Fredholm BB, Sandberg G. Inhibition by xanthine derivatives of adenosine receptor-stimulated cyclic adenosine 3',5'-monophosphate accumulation in rat and guinea-pig thymocytes. British Journal of Pharmacology. 80: 639-44. PMID 6100843 DOI: 10.1111/j.1476-5381.1983.tb10053.x  0.475
1987 Edvinsson L, Fredholm BB. Characterization of adenosine receptors in isolated cerebral arteries of cat. British Journal of Pharmacology. 80: 631-7. PMID 6100842 DOI: 10.1111/j.1476-5381.1983.tb10052.x  0.421
1987 Perez MT, Ehinger BE, Lindström K, Fredholm BB. Release of endogenous and radioactive purines from the rabbit retina. Brain Research. 398: 106-12. PMID 3801882 DOI: 10.1016/0006-8993(86)91255-2  0.331
1987 Nordstedt C, Jondal M, Fredholm BB. Activation of protein kinase C inhibits prostaglandin- and potentiates adenosine receptor-stimulated accumulation of cyclic AMP in a human T-cell leukemia line. Febs Letters. 220: 57-60. PMID 3038616 DOI: 10.1016/0014-5793(87)80875-X  0.763
1987 Brodie MS, Lee K, Fredholm BB, StÃ¥hle L, Dunwiddie TV. Central versus peripheral mediation of responses to adenosine receptor agonists: evidence against a central mode of action. Brain Research. 415: 323-30. PMID 3038272 DOI: 10.1016/0006-8993(87)90214-9  0.38
1987 Fredholm BB, Jondal M, Nordstedt C. The adenosine receptor mediated accumulation of cyclic AMP in Jurkat cells is enhanced by a lectin and by phorbol esters. Biochemical and Biophysical Research Communications. 145: 344-9. PMID 3036123 DOI: 10.1016/0006-291X(87)91327-1  0.78
1987 Fredholm BB, Lindgren E. Effects of N-ethylmaleimide and forskolin on noradrenaline release from rat hippocampal slices. Evidence that prejunctional adenosine and alpha-receptors are linked to N-proteins but not to adenylate cyclase. Acta Physiologica Scandinavica. 130: 95-105. PMID 3035877 DOI: 10.1111/j.1748-1716.1987.tb08116.x  0.33
1987 Härfstrand A, Fredholm B, Fuxe K. Inhibitory effects of neuropeptide Y on cyclic AMP accumulation in slices of the nucleus tractus solitarius region of the rat. Neuroscience Letters. 76: 185-90. PMID 3035437 DOI: 10.1016/0304-3940(87)90713-0  0.587
1987 Nordstedt C, Fredholm BB. Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues. Naunyn-Schmiedeberg's Archives of Pharmacology. 335: 136-42. PMID 3031515 DOI: 10.1007/Bf00177714  0.765
1987 Fredholm BB, Lindgren E, Lindström K, Nordstedt C. Alpha-adrenoceptor stimulation, but not muscarinic stimulation, increases cyclic AMP accumulation in brain slices due to protein kinase C mediated enhancement of adenosine receptor effects. Acta Physiologica Scandinavica. 131: 543-51. PMID 2894742 DOI: 10.1111/J.1748-1716.1987.Tb08274.X  0.756
1987 Ng J, Fredholm BB, Jondal M. Studies on the calcium dependence of human NK cell killing. Biochemical Pharmacology. 36: 3943-9. PMID 2446626 DOI: 10.1016/0006-2952(87)90462-X  0.314
1987 Hu PS, Lindgren E, Jacobson KA, Fredholm BB. Interaction of dihydropyridine calcium channel agonists and antagonists with adenosine receptors. Pharmacology & Toxicology. 61: 121-5. PMID 2444963 DOI: 10.1111/J.1600-0773.1987.Tb01788.X  0.533
1987 Fredholm BB, Jacobson KA, Jonzon B, Kirk KL, Li YO, Daly JW. Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo. Journal of Cardiovascular Pharmacology. 9: 396-400. PMID 2438501 DOI: 10.1097/00005344-198704000-00003  0.556
1986 Fredholm BB, Lindström K. The xanthine derivative 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine (HWA 285) enhances the actions of adenosine. Acta Pharmacologica Et Toxicologica. 58: 187-92. PMID 3012941 DOI: 10.1111/J.1600-0773.1986.TB00093.X  0.423
1986 Fredholm BB, Lindgren E. Possible involvement of the Ni-protein in the prejunctional inhibitory effect of a stable adenosine analogue (R-PIA) on noradrenaline release in the rat hippocampus. Acta Physiologica Scandinavica. 126: 307-9. PMID 3010641 DOI: 10.1111/J.1748-1716.1986.TB07819.X  0.332
1986 Fredholm BB, Jonzon B, Lindström K. Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices. Naunyn-Schmiedeberg's Archives of Pharmacology. 332: 173-8. PMID 3010142 DOI: 10.1007/BF00511409  0.485
1986 Fredholm BB, Sollevi A. Cardiovascular effects of adenosine. Clinical Physiology (Oxford, England). 6: 1-21. PMID 3002708 DOI: 10.1111/J.1475-097X.1986.TB00139.X  0.471
1986 Dunér-Engström M, Fredholm BB, Larsson O, Lundberg JM, Saria A. Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man. The Journal of Physiology. 373: 87-96. PMID 2427699 DOI: 10.1113/Jphysiol.1986.Sp016036  0.467
1986 Dunér-Engström M, Larsson O, Fredholm BB. Continuous monitoring of potassium efflux from rat parotid gland fragments by potassium selective electrodes. Acta Physiologica Scandinavica. 126: 551-5. PMID 2424270 DOI: 10.1111/J.1748-1716.1986.Tb07854.X  0.636
1986 Larsson O, Dunér-Engström M, Lundberg JM, Fredholm BB, Anggård A. Effects of VIP, PHM and substance P on blood vessels and secretory elements of the human submandibular gland. Regulatory Peptides. 13: 319-26. PMID 2422707 DOI: 10.1016/0167-0115(86)90049-2  0.713
1986 Fuxe K, Härfstrand A, Agnati LF, Kalia M, Fredholm B, Svensson T, Gustafsson J, Lang R, Ganten D. Central Catecholamine-Neuropeptide Y Interactions at the Pre- and Postsynaptic Level in Cardiovascular Centers Journal of Cardiovascular Pharmacology. 10: S1-S13. DOI: 10.1097/00005344-198609002-00001  0.614
1985 Jonzon B, Fredholm BB. Adenosine mechanisms are not affected by antidepressant concentrations of desipramine. The Journal of Pharmacy and Pharmacology. 36: 846-8. PMID 6151982 DOI: 10.1111/j.2042-7158.1984.tb04892.x  0.424
1985 Fredholm BB, Jondal M, Lanefelt F, Ng J. Effect of 5'-methylthioadenosine, 3-deazaadenosine, and related compounds on human natural killer cell activity. Relation to cyclic AMP and methylation potential. Scandinavian Journal of Immunology. 20: 511-8. PMID 6096962 DOI: 10.1111/j.1365-3083.1984.tb01033.x  0.35
1985 Elfman L, Lindgren E, Walum E, Fredholm BB. Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells. Acta Pharmacologica Et Toxicologica. 55: 297-302. PMID 6095594 DOI: 10.1111/J.1600-0773.1984.TB01985.X  0.4
1985 Jonzon B, Fredholm BB. Release of purines, noradrenaline, and GABA from rat hippocampal slices by field stimulation. Journal of Neurochemistry. 44: 217-24. PMID 3964829 DOI: 10.1111/j.1471-4159.1985.tb07133.x  0.325
1985 Jakobson KA, Kirk KL, Daly JW, Jonzon B, Li YO, Fredholm BB. A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo. Acta Physiologica Scandinavica. 125: 341-2. PMID 3000136 DOI: 10.1111/J.1748-1716.1985.Tb07725.X  0.332
1985 Fredholm BB, Lindgren E, Lindström K. Treatment with N-ethylmaleimide selectively reduces adenosine receptor-mediated decreases in cyclic AMP accumulation in rat hippocampal slices. British Journal of Pharmacology. 86: 509-13. PMID 2996680 DOI: 10.1111/j.1476-5381.1985.tb08922.x  0.465
1985 Edvinsson L, Fredholm BB, Hamel E, Jansen I, Verrecchia C. Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat. Neuroscience Letters. 58: 213-7. PMID 2995876 DOI: 10.1016/0304-3940(85)90166-1  0.308
1985 Jonzon B, Fredholm BB, Nilsson J. Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells. Journal of Cellular Physiology. 124: 451-456. PMID 2995420 DOI: 10.1002/Jcp.1041240314  0.409
1985 Li YO, Fredholm BB. Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors. Acta Physiologica Scandinavica. 124: 253-9. PMID 2990167 DOI: 10.1111/J.1748-1716.1985.TB07659.X  0.496
1985 Bickford PC, Fredholm BB, Dunwiddie TV, Freedman R. Inhibition of Purkinje cell firing by systemic administration of phenylisopropyl adenosine: effect of central noradrenaline depletion by DSP4. Life Sciences. 37: 289-97. PMID 2989646 DOI: 10.1016/0024-3205(85)90655-1  0.376
1985 Fredholm BB. On the mechanism of action of theophylline and caffeine. Acta Medica Scandinavica. 217: 149-53. PMID 2986418 DOI: 10.1111/J.0954-6820.1985.TB01650.X  0.314
1985 Dunwiddie TV, Fredholm BB, Jonzon B, Sandberg G. The adenosine receptor activity of EMD 28422, a purine derivative with reported actions on benzodiazepine receptors. British Journal of Pharmacology. 84: 625-30. PMID 2985159 DOI: 10.1111/J.1476-5381.1985.Tb16142.X  0.478
1985 Fredholm BB, Bergman B, Lindström K. Actions of enprofylline in the rat hippocampus. Acta Physiologica Scandinavica. 123: 183-9. PMID 2984896 DOI: 10.1111/J.1748-1716.1985.TB07576.X  0.311
1985 Fastbom J, Fredholm BB. Inhibition of [3H] glutamate release from rat hippocampal slices by L-phenylisopropyladenosine. Acta Physiologica Scandinavica. 125: 121-3. PMID 2864783 DOI: 10.1111/J.1748-1716.1985.TB07698.X  0.353
1985 Sollevi A, Kaijser L, Fredholm BB. Release Of Adenosine From The Ischemic Human Heart: 201 Pediatric Research. 19: 777-777. DOI: 10.1203/00006450-198507000-00221  0.312
1984 Gazelius B, Sidhagen B, Fredholm BB. Adenosine and adenosine analogues increase blood flow in oral mucosa. Acta Physiologica Scandinavica. 120: 333-6. PMID 6741570 DOI: 10.1111/J.1748-1716.1984.TB07392.X  0.319
1984 Sollevi A, Fredholm BB. Influence of adenosine on the vascular responses to sympathetic nerve stimulation in the canine subcutaneous adipose tissue. Acta Physiologica Scandinavica. 119: 15-24. PMID 6650202 DOI: 10.1111/J.1748-1716.1983.TB07300.X  0.356
1984 Lagercrantz H, Yamamoto Y, Fredholm BB, Prabhakar NR, von Euler C. Adenosine analogues depress ventilation in rabbit neonates. Theophylline stimulation of respiration via adenosine receptors? Pediatric Research. 18: 387-90. PMID 6326038 DOI: 10.1203/00006450-198404000-00018  0.335
1984 Fredholm BB, Dunwiddie TV, Bergman B, Lindström K. Levels of adenosine and adenine nucleotides in slices of rat hippocampus. Brain Research. 295: 127-36. PMID 6324948 DOI: 10.1016/0006-8993(84)90823-0  0.356
1984 Fredholm BB, Lindgren E. The effect of alkylxanthines and other phosphodiesterase inhibitors on adenosine-receptor mediated decrease in lipolysis and cyclic AMP accumulation in rat fat cells. Acta Pharmacologica Et Toxicologica. 54: 64-71. PMID 6322517 DOI: 10.1111/J.1600-0773.1984.TB01896.X  0.438
1984 Lundberg JM, Hua Y, Fredholm BB. Capsaicin-induced stimulation of the guinea-pig atrium. Involvement of a novel sensory transmitter or a direct action on myocytes? Naunyn-Schmiedeberg's Archives of Pharmacology. 325: 176-82. PMID 6201751 DOI: 10.1007/BF00506198  0.537
1984 Fredholm BB, Jonzon B, Lindgren E. Changes in noradrenaline release and in beta receptor number in rat hippocampus following long-term treatment with theophylline or L-phenylisopropyladenosine. Acta Physiologica Scandinavica. 122: 55-9. PMID 6095597 DOI: 10.1111/J.1748-1716.1984.TB07481.X  0.403
1984 Jonzon B, Fredholm BB. Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus. Life Sciences. 35: 1971-9. PMID 6092809 DOI: 10.1016/0024-3205(84)90478-8  0.38
1984 Enyedi P, Fredholm BB. Calcium-dependent enhancement by carbachol of the VIP-induced cyclic AMP accumulation in cat submandibular gland. Acta Physiologica Scandinavica. 120: 523-8. PMID 6091414 DOI: 10.1111/J.1748-1716.1984.TB07416.X  0.333
1984 Dunwiddie TV, Fredholm BB. Adenosine receptors mediating inhibitory electrophysiological responses in rat hippocampus are different from receptors mediating cyclic AMP accumulation. Naunyn-Schmiedeberg's Archives of Pharmacology. 326: 294-301. PMID 6090957 DOI: 10.1007/Bf00501433  0.444
1984 Fredholm BB, Vernet L. Accumulation and inactivation of adenosine by fat cells from hypothyroid rats. Acta Physiologica Scandinavica. 121: 155-63. PMID 6089504 DOI: 10.1111/J.1748-1716.1984.TB07442.X  0.388
1983 Fredholm BB, Lindgren E, Lindström K, Vernet L. The effect of some drugs with purported antianoxic effect on veratridine-induced purine release from isolated rat hypothalamic synaptosomes. Acta Pharmacologica Et Toxicologica. 53: 236-44. PMID 6637513 DOI: 10.1111/J.1600-0773.1983.TB01131.X  0.33
1983 Fredholm BB, Herrera-Marschitz M, Jonzon B, Lindström K, Ungerstedt U. On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat. Pharmacology, Biochemistry, and Behavior. 19: 535-41. PMID 6634904 DOI: 10.1016/0091-3057(83)90131-4  0.663
1983 Lerner U, Fredholm BB. Studies on the mechanisms by which 2-chloroadenosine stimulates bone resorption in tissue culture. Biochimica Et Biophysica Acta. 757: 226-34. PMID 6405798 DOI: 10.1016/0304-4165(83)90113-7  0.305
1983 Fredholm BB, Jonzon B, Lindström K. Adenosine receptor mediated increases and decreases in cyclic AMP in hippocampal slices treated with forskolin. Acta Physiologica Scandinavica. 117: 461-3. PMID 6308960 DOI: 10.1111/J.1748-1716.1983.TB00022.X  0.472
1983 Lanefelt F, Martinsson A, Hjemdahl P, Fredholm BB. Comparison of the effects of different arachidonic acid metabolites on cyclic nucleotide accumulation in human peripheral lymphocytes. Acta Pharmacologica Et Toxicologica. 51: 336-44. PMID 6295066 DOI: 10.1111/J.1600-0773.1982.TB01034.X  0.312
1983 Fuxe K, Ogren SO, Agnati LF, Benfenati F, Fredholm B, Andersson K, Zini I, Eneroth P. Chronic antidepressant treatment and central 5-HT synapses. Neuropharmacology. 22: 389-400. PMID 6190101 DOI: 10.1016/0028-3908(83)90188-0  0.473
1983 Ullberg M, Jondal M, Lanefelt F, Fredholm BB. Inhibition of human NK cell cytotoxicity by induction of cyclic AMP depends on impaired target cell recognition. Scandinavian Journal of Immunology. 17: 365-73. PMID 6188204 DOI: 10.1111/j.1365-3083.1983.tb00801.x  0.342
1983 Fredholm BB, Hedqvist P, Lindström K, Wennmalm M. Release of nucleosides and nucleotides from the rabbit heart by sympathetic nerve stimulation. Acta Physiologica Scandinavica. 116: 285-95. PMID 6132522 DOI: 10.1111/J.1748-1716.1982.TB07142.X  0.353
1982 Sollevi A, Fredholm BB. The antilipolytic effect of endogenous and exogenous adenosine in canine adipose tissue in situ. Acta Physiologica Scandinavica. 113: 53-60. PMID 7315438 DOI: 10.1111/J.1748-1716.1981.TB06861.X  0.393
1982 Fredholm BB. Release of adenosine from rat lung by antigen and compound 48/80. Acta Physiologica Scandinavica. 111: 507-8. PMID 7304212 DOI: 10.1111/J.1748-1716.1981.TB06772.X  0.338
1982 Fredholm BB, Fried G, Hedqvist P. Origin of adenosine released from rat vas deferens by nerve stimulation. European Journal of Pharmacology. 79: 233-43. PMID 7094997 DOI: 10.1016/0014-2999(82)90629-X  0.357
1982 Zetterström T, Vernet L, Ungerstedt U, Tossman U, Jonzon B, Fredholm BB. Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre. Neuroscience Letters. 29: 111-5. PMID 7088412 DOI: 10.1016/0304-3940(82)90338-X  0.627
1982 Fredholm BB. Adenosine actions and adenosine receptors after 1 week treatment with caffeine. Acta Physiologica Scandinavica. 115: 283-6. PMID 6291335 DOI: 10.1111/J.1748-1716.1982.TB07078.X  0.48
1982 Fredholm BB, Lundberg JM. VIP-induced cyclic AMP formation in the cat submandibular gland. Potentiation by carbacholine. Acta Physiologica Scandinavica. 114: 157-9. PMID 6291326 DOI: 10.1111/j.1748-1716.1982.tb06966.x  0.476
1982 Fredholm BB, Lunell NO, Persson B, Wager J. Development of tolerance to the metabolic actions of beta 2-adrenoceptor stimulating drugs. Acta Obstetricia Et Gynecologica Scandinavica. Supplement. 108: 53-9. PMID 6289598 DOI: 10.3109/00016348209155346  0.334
1982 Fredholm BB, Persson CG. Xanthine derivatives as adenosine receptor antagonists. European Journal of Pharmacology. 81: 673-6. PMID 6288418 DOI: 10.1016/0014-2999(82)90359-4  0.358
1982 Bistoletti P, Ölund A, Lunell N, Fredholm B. Decreased Adenosine 3',5'-Cyclic Monophosphate Concentration in Amniotic Fluid during Rivanol-Induced Abortion Gynecologic and Obstetric Investigation. 13: 184-188. PMID 6284597 DOI: 10.1159/000299512  0.3
1982 Gustafsson L, Fredholm BB, Hedqvist P. Theophylline interferes with the modulatory role of endogenous adenosine on cholinergic neurotransmission in guinea pig ileum. Acta Physiologica Scandinavica. 111: 269-80. PMID 6274157 DOI: 10.1111/J.1748-1716.1981.TB06736.X  0.416
1982 Sydbom A, Fredholm BB. On the mechanism by which theophylline inhibits histamine release from rat mast cells. Acta Physiologica Scandinavica. 114: 243-51. PMID 6182749 DOI: 10.1111/J.1748-1716.1982.TB06978.X  0.375
1982 Enyedi P, Fredholm BB, Lundberg JM, Anggård A. Carbachol potentiates the cyclic AMP-stimulating effect of VIP in cat submandibular gland. European Journal of Pharmacology. 79: 139-43. PMID 6177536 DOI: 10.1016/0014-2999(82)90586-6  0.521
1982 Fredholm BB, Jonzon B, Lindgren E, Lindström K. Adenosine receptors mediating cyclic AMP production in the rat hippocampus. Journal of Neurochemistry. 39: 165-75. PMID 6123548 DOI: 10.1111/j.1471-4159.1982.tb04715.x  0.478
1981 Sollevi A, Fredholm BB. Role of adenosine in adipose tissue circulation. Acta Physiologica Scandinavica. 112: 293-8. PMID 7293798 DOI: 10.1111/J.1748-1716.1981.TB06819.X  0.32
1981 Sollevi A, Hjemdahl P, Fredholm BB. Endogenous adenosine inhibits lipolysis induced by nerve stimulation without inhibiting noradrenaline release in canine subcutaneous adipose tissue in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 112-9. PMID 7242697 DOI: 10.1007/BF00505303  0.37
1981 Dunwiddie TV, Hoffer BJ, Fredholm BB. Alkylxanthines elevate hippocampal excitability. Evidence for a role of endogenous adenosine. Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 326-30. PMID 6267486 DOI: 10.1007/Bf00501365  0.385
1981 Sydbom A, Fredholm B, Uvnäs B. Evidence against a role of cyclic nucleotides in the regulation of anaphylactic histamine release in isolated rat mast cells. Acta Physiologica Scandinavica. 112: 47-56. PMID 6169252 DOI: 10.1111/J.1748-1716.1981.Tb06781.X  0.329
1980 Fredholm BB, Hjemdahl P, Hammarström S. Stimulation and inhibition of cyclic AMP formation in isolated rat fat cell by prostacyclin (PGI2). Biochemical Pharmacology. 29: 661-3. PMID 6245658 DOI: 10.1016/0006-2952(80)90396-2  0.316
1980 Hökfelt T, Lundberg JM, Schultzberg M, Johansson O, Skirboll L, AnggÃ¥rd A, Fredholm B, Hamberger B, Pernow B, Rehfeld J, Goldstein M. Cellular localization of peptides in neural structures. Proceedings of the Royal Society of London. Series B, Biological Sciences. 210: 63-77. PMID 6159653 DOI: 10.1098/Rspb.1980.0119  0.465
1980 Fredholm BB, Sydbom A. Are the anti-allergic actions of theophylline due to antagonism at the adenosine receptor. Agents and Actions. 10: 145-7. PMID 6155768 DOI: 10.1007/BF02024198  0.337
1980 Fredholm BB, Vernet L. Release of 3H-nucleosides from 3H-adenine labelled hypothalamic synaptosomes. Acta Physiologica Scandinavica. 106: 97-107. PMID 228529 DOI: 10.1111/J.1748-1716.1979.TB06377.X  0.312
1979 Luchelli-Fortis MA, Fredholm BB, Langer SZ. Release of radioactive purines from cat nictitating membrane labeled with 3H-adenine. European Journal of Pharmacology. 58: 389-97. PMID 510374 DOI: 10.1016/0014-2999(79)90309-1  0.323
1979 Hedqvist P, Fredholm BB. Inhibitory effect of adenosine on adrenergic neuroeffector transmission in the rabbit heart. Acta Physiologica Scandinavica. 105: 120-2. PMID 420012 DOI: 10.1111/J.1748-1716.1979.TB06321.X  0.309
1979 Fredholm BB, Brodin K, Strandberg K. On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors. Acta Pharmacologica Et Toxicologica. 45: 336-44. PMID 231892 DOI: 10.1111/J.1600-0773.1979.TB02402.X  0.334
1979 Fredholm BB, Farnebo LO, Hamberger B. Plasma catecholamines, cyclic AMP and metabolic substrates in hemorrhagic shock of the rat. The effect of adrenal demedullation and 6-OH-dopamine treatment. Acta Physiologica Scandinavica. 105: 481-95. PMID 222118 DOI: 10.1111/j.1748-1716.1979.tb00113.x  0.306
1979 Fredholm BB, Hjemdahl P. Uptake and release of adenosine in isolated rat fat cells. Acta Physiologica Scandinavica. 105: 257-67. PMID 220845 DOI: 10.1111/J.1748-1716.1979.TB06340.X  0.388
1979 Fredholm BB, Hedqvist P, Vernet L. Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5'-nucleotidase and adenosine deaminase. Biochemical Pharmacology. 27: 2845-50. PMID 216371 DOI: 10.1016/0006-2952(78)90199-5  0.338
1979 Fredholm BB, Sandberg G, Ernström U. Cyclic AMP in freshly prepared thymocyte suspensions, Evidence for stimulation by endogenous adenosine. Biochemical Pharmacology. 27: 2675-82. PMID 215164 DOI: 10.1016/0006-2952(78)90041-2  0.407
1979 Gustafsson L, Hedqvist P, Fredholm BB, Lundgren G. Inhibition of acetylcholine release in guinea pig ileum by adenosine. Acta Physiologica Scandinavica. 104: 469-78. PMID 214999 DOI: 10.1111/J.1748-1716.1978.TB06302.X  0.389
1979 Fredholm BB, Hedqvist P. Release of 3H-purines from [3H]-adenine labelled rabbit kidney following sympathetic nerve stimulation, and its inhibition by alpha-adrenoceptor blockage. British Journal of Pharmacology. 64: 239-45. PMID 30505 DOI: 10.1111/j.1476-5381.1978.tb17295.x  0.337
1979 Fredholm BB. Are methylxanthine effects due to antagonism of endogenous adenosine? Trends in Pharmacological Sciences. 1: 129-132. DOI: 10.1016/0165-6147(79)90046-4  0.324
1978 Fuxe K, Fredholm BB, Agnati LF, Corrodi H. Dopamine receptors and ergot drugs. Evidence that an ergolene derivative is a differential agonist at subcortical limbic dopamine receptors. Brain Research. 146: 295-311. PMID 647392 DOI: 10.1016/0006-8993(78)90975-7  0.597
1978 Fuxe K, Fredholm BB, Agnati LF, Ogren SO, Everitt BJ, Jonsson G, Gustafsson JA. Interaction of ergot drugs with central monoamine systems. Evidence for a high potential in the treatment of mental and neurological disorders. Pharmacology. 16: 99-134. PMID 643908 DOI: 10.1159/000136813  0.553
1978 Fredholm BB. Effect of adenosine, adenosine analogues and drugs inhibiting adenosine inactivation on lipolysis in rat fat cells. Acta Physiologica Scandinavica. 102: 191-8. PMID 626097 DOI: 10.1111/J.1748-1716.1978.TB06062.X  0.432
1978 Svensson J, Fredholm BB. Vasoconstrictor effect of thromboxane A2. Acta Physiologica Scandinavica. 101: 366-8. PMID 596211 DOI: 10.1111/J.1748-1716.1977.TB06019.X  0.302
1978 Fuxe K, Fredholm BB, Ogren SO, Agnati LF, Hökfelt T, Gustafsson JA. Ergot drugs and central monoaminergic mechanisms: a histochemical, biochemical and behavioral analysis. Federation Proceedings. 37: 2181-91. PMID 350633  0.506
1978 Fuxe K, Fredholm BB, Ogren SO, Agnati LF, Hökfelt T, Gustafsson JA. Pharmacological and biochemical evidence for the dopamine agonistic effect of bromocriptine. Acta Endocrinologica. Supplementum. 216: 27-56. PMID 347864  0.484
1978 Hedqvist P, Fredholm BB, Olundh S. Antagonistic effects of theophylline and adenosine on adrenergic neuroeffector transmission in the rabbit kidney. Circulation Research. 43: 592-8. PMID 210977 DOI: 10.1161/01.RES.43.4.592  0.406
1978 Hjemdahl P, Fredholm BB. Direct antilipolytic effect of acidosis in isolated rat adipocytes. Acta Physiologica Scandinavica. 101: 294-301. PMID 22988 DOI: 10.1111/J.1748-1716.1977.TB06011.X  0.313
1977 Belfrage E, Fredholm BB, Rosell S. Effect of catechol-O-methyl-transferase (COMT) inhibition on the vascular and metabolic responses to noradrenaline, isoprenaline and sympathetic nerve stimulation in canine subcutaneous adipose tissue. Naunyn-Schmiedeberg's Archives of Pharmacology. 300: 11-7. PMID 593427 DOI: 10.1007/BF00505074  0.523
1977 Fredholm BB, Belfrage E, Blaschke E. Changes in ATP and cyclic nucleotide levels during sympathetic nerve stimulation in canine subcutaneous adipose tissue in situ. Acta Physiologica Scandinavica. 99: 313-22. PMID 192046 DOI: 10.1111/J.1748-1716.1977.TB10384.X  0.328
1976 Hedqvist P, Fredholm BB. Effects of adenosine on adrenergic neurotransmission; prejunctional inhibition and postjunctional enhancement. Naunyn-Schmiedeberg's Archives of Pharmacology. 293: 217-23. PMID 183154 DOI: 10.1007/BF00507344  0.377
1976 Fredholm BB, Fuxe K, Agnati L. Effect of some phosphodiesterase inhibitors on central dopamine mechanisms. European Journal of Pharmacology. 38: 31-8. PMID 182507 DOI: 10.1016/0014-2999(76)90198-9  0.534
1976 Fredholm BB, Hamberg M. Metabolism and effect of prostaglandin H2 in adipose tissue. Prostaglandins. 11: 507-18. PMID 181790 DOI: 10.1016/0090-6980(76)90098-8  0.352
1976 Fredholm BB. Release of adenosine-like material from isolated perfused dog adipose tissue following sympathetic nerve stimulation and its inhibition by adrenergic alpha-receptor blockade. Acta Physiologica Scandinavica. 96: 122-30. PMID 179276 DOI: 10.1111/J.1748-1716.1976.TB10211.X  0.378
1976 Fredholm BB, Guschin I, Elwin K, Schwab G, Uvnäs B. Cyclic AMP independent inhibition by papaverine of histamine release induced by compound 48/80. Biochemical Pharmacology. 25: 1583-8. PMID 60103 DOI: 10.1016/0006-2952(76)90467-6  0.358
1976 Hjemdahl P, Fredholm BB. Cyclic AMP-dependent and independent inhibition of lipolysis by adenosine and decreased pH. Acta Physiologica Scandinavica. 96: 170-9. PMID 3945 DOI: 10.1111/J.1748-1716.1976.TB10186.X  0.363
1975 Fredholm BB, Hedqvist P. Indomethacin-induced increase in noradrenaline turnover in some rat organs. British Journal of Pharmacology. 54: 295-300. PMID 1164589 DOI: 10.1111/j.1476-5381.1975.tb07568.x  0.31
1975 Fredholm BB, Hedqvist P. Indomethacin and the role of prostaglandins in adipose tissue. Biochemical Pharmacology. 24: 61-6. PMID 164868 DOI: 10.1016/0006-2952(75)90314-7  0.324
1974 Fredholm BB. Inhibition of free fatty acid mobilization by nicotinic acid in canine subcutaneous adipose tissue in situ: combination of lipolysis inhibition and increased re-esterification. Acta Pharmacologica Et Toxicologica. 33: 300-7. PMID 4800676 DOI: 10.1111/J.1600-0773.1973.TB01530.X  0.327
1974 Fredholm BB. Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ. Acta Physiologica Scandinavica. 90: 226-36. PMID 4360701 DOI: 10.1111/J.1748-1716.1974.TB05581.X  0.346
1973 Fredholm B, Hedqvist P. Increased release of noradrenaline from stimulated guinea pig vas deferens after indomethacin treatment. Acta Physiologica Scandinavica. 87: 570-572. PMID 4724995 DOI: 10.1111/J.1748-1716.1973.Tb05424.X  0.316
1973 Fredholm BB, Hedqvist P. Role of pre- and postjunctional inhibition by prostaglandin E2 of lipolysis induced by sympathetic nerve stimulation in dog subcutaneous adipose tissue in situ. British Journal of Pharmacology. 47: 711-8. PMID 4723796 DOI: 10.1111/j.1476-5381.1973.tb08198.x  0.309
1972 Fredholm BB. Effects of malate and oxaloacetate in canine subcutaneous adipose tissue. Acta Physiologica Scandinavica. 84: 34-9. PMID 5029382 DOI: 10.1111/J.1748-1716.1972.TB05153.X  0.313
1972 Fredholm BB. Inhibition by -hydroxybutyrate of lipolysis induced by sympathetic nerve activity in canine subcutaneous adipose tissue in situ. Metabolism: Clinical and Experimental. 21: 125-31. PMID 5009388 DOI: 10.1016/0026-0495(72)90064-9  0.309
1971 Fredholm BB, Frisk-Holmberg M. Lipolysis in canine subcutaneous adipose tissue following release of endogenous histamine. European Journal of Pharmacology. 13: 254-8. PMID 5544077 DOI: 10.1016/0014-2999(71)90157-9  0.301
1971 Fredholm BB. The effect of lactate in canine subcutaneous adipose tissue in situ. Acta Physiologica Scandinavica. 81: 110-23. PMID 5543311 DOI: 10.1111/J.1748-1716.1971.TB04881.X  0.303
1971 Ballard K, Fredholm BB, Meng HC, Rosell S. Heparin-induced release of lipase activity from perfused canine subcutaneous adipose tissue. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 137: 1490-3. PMID 5138478 DOI: 10.3181/00379727-137-35816  0.479
1971 Fredholm BB, Karlsson J. Metabolic effects of prolonged sympathetic nerve stimulation in canine subcutaneous adipose tissue. Acta Physiologica Scandinavica. 80: 567-76. PMID 4395438 DOI: 10.1111/J.1748-1716.1970.TB04824.X  0.376
1970 Fredholm BB, Rosell S. Effects of prostaglandin E1 in canine subcutaneous adipose tissue in situ. Acta Physiologica Scandinavica. 80: 450-8. PMID 5493808 DOI: 10.1111/j.1748-1716.1970.tb04813.x  0.545
1970 Fredholm BB, Rosell S. Fate of 3H-noradrenaline in canine subcutaneous adipose tissue. Acta Physiologica Scandinavica. 80: 404-11. PMID 5486466 DOI: 10.1111/j.1748-1716.1970.tb04804.x  0.519
1970 Fredholm BB, Oberg B, Rosell S. Effects of vasoactive drugs on circulation in canine subcutaneous adipose tissue. Acta Physiologica Scandinavica. 79: 564-74. PMID 5472122 DOI: 10.1111/j.1748-1716.1970.tb04759.x  0.485
1970 Fredholm BB, Rosell S, Strandberg K. Release of prostaglandin-like material from canine subcutaneous adipose tissue by nerve stimulation. Acta Physiologica Scandinavica. 79: 18A-19A. PMID 5454886  0.449
1969 Fredholm BB, Linde B, Oberg B, Rosell S. Studies on the capillary exchange function in canine subcutaneous adipose tissue. Bibliotheca Anatomica. 10: 241-3. PMID 5407371  0.397
1968 Fredholm BB, Meng HC, Oberg B, Rosell S. Vascular and metabolic effects of histamine and compound 48/80 in subcutaneous adipose tissue. British Journal of Pharmacology. 34: 197P-198P. PMID 5676007  0.414
1968 Fredholm BB, Meng HC, Rosell S. Release of free fatty acids from canine subcutaneous adipose tissue by histamine and compound 48-80. Life Sciences. 7: 1209-15. PMID 4181282 DOI: 10.1016/0024-3205(68)90291-9  0.487
1967 Fredholm BB, Oberg B, Rosell S. Vascular reactions in canine subcutaneous adipose tissue following prostaglandin E1 (PGE1). Acta Pharmacologica Et Toxicologica. 25: Suppl 4:28. PMID 4230880 DOI: 10.1111/J.1600-0773.1967.Tb03018.X  0.473
1966 Fredholm B, Sedvall G. Influence of sympathetic nerve stimulation on noradrenaline stores in the rat salivary gland Life Sciences. 5: 2023-2032. DOI: 10.1016/0024-3205(66)90275-X  0.524
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