Jeannie Chen - Publications

Affiliations: 
Cell and Neurobiology: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Neuroscience

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hsieh CL, Yao Y, Gurevich VV, Chen J. Arrestin facilitates rhodopsin dephosphorylation . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35332081 DOI: 10.1523/JNEUROSCI.0141-22.2022  0.407
2020 Samaranayake S, Vishnivetskiy SA, Shores CR, Thibeault KC, Kook S, Chen J, Burns ME, Gurevich EV, Gurevich VV. Biological role of arrestin-1 oligomerization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32948676 DOI: 10.1523/Jneurosci.0749-20.2020  0.419
2020 Silverman D, Chai Z, Yue WWS, Ramisetty SK, Bekshe Lokappa S, Sakai K, Frederiksen R, Bina P, Tsang SH, Yamashita T, Chen J, Yau KW. Dark noise and retinal degeneration from D190N-rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873651 DOI: 10.1073/Pnas.2010417117  0.456
2020 Chen NS, Ingram NT, Frederiksen R, Sampath AP, Chen J, Fain GL. Diminished Cone Sensitivity in cpfl3 Mice Is Caused by Defective Transducin Signaling. Investigative Ophthalmology & Visual Science. 61: 26. PMID 32315379 DOI: 10.1167/Iovs.61.4.26  0.416
2019 Lokappa SB, Cornwall MC, Chen J. Isoelectric Focusing to Quantify Rhodopsin Phosphorylation in Mouse Retina. Bio-Protocol. 9: e3300. PMID 33654813 DOI: 10.21769/BioProtoc.3300  0.319
2019 Wang T, Pahlberg J, Cafaro J, Frederiksen R, Cooper AJ, Sampath AP, Field GD, Chen J. Activation of rod input in a model of retinal degeneration reverses retinal remodeling and induces formation of functional synapses and recovery of visual signaling in the adult retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31285302 DOI: 10.1523/Jneurosci.2902-18.2019  0.409
2019 Yue WWS, Silverman D, Ren X, Frederiksen R, Sakai K, Yamashita T, Shichida Y, Cornwall MC, Chen J, Yau KW. Elementary response triggered by transducin in retinal rods. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796193 DOI: 10.1073/Pnas.1817781116  0.431
2018 Wang T, Reingruber J, Woodruff ML, Majumder A, Camarena A, Artemyev NO, Fain GL, Chen J. The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx. The Journal of Biological Chemistry. PMID 30126843 DOI: 10.1074/Jbc.Ra118.004459  0.434
2018 Samaranayake S, Song X, Vishnivetskiy SA, Chen J, Gurevich EV, Gurevich VV. Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1. Frontiers in Molecular Neuroscience. 11: 203. PMID 29973866 DOI: 10.3389/Fnmol.2018.00203  0.383
2018 Vinberg F, Chen J, Kefalov VJ. Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors. Progress in Retinal and Eye Research. PMID 29883715 DOI: 10.1016/J.Preteyeres.2018.06.001  0.375
2018 Vinberg F, Peshenko IV, Chen J, Dizhoor AM, Kefalov VJ. Guanylate Cyclase Activating Protein 2 Contributes to Phototransduction and Light Adaptation in Mouse Cone Photoreceptors. The Journal of Biological Chemistry. PMID 29549122 DOI: 10.1074/Jbc.Ra117.001574  0.408
2017 LaVail MM, Nishikawa S, Steinberg RH, Naash MI, Duncan JL, Trautmann N, Matthes MT, Yasumura D, Lau-Villacorta C, Chen J, Peterson WM, Yang H, Flannery JG. Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration. Experimental Eye Research. PMID 29122605 DOI: 10.1016/J.Exer.2017.10.023  0.326
2017 Vinberg F, Wang T, De Maria A, Zhao H, Bassnett S, Chen J, Kefalov VJ. The Na(+)/Ca(2+), K(+) exchanger NCKX4 is required for efficient cone-mediated vision. Elife. 6. PMID 28650316 DOI: 10.7554/Elife.24550  0.35
2017 Rose K, Walston ST, Chen J. Separation of photoreceptor cell compartments in mouse retina for protein analysis. Molecular Neurodegeneration. 12: 28. PMID 28399904 DOI: 10.1186/S13024-017-0171-2  0.424
2017 Wang T, Tsang SH, Chen J. Two pathways of rod photoreceptor cell death induced by elevated cGMP. Human Molecular Genetics. PMID 28379353 DOI: 10.1093/Hmg/Ddx121  0.409
2016 Sakurai K, Vinberg F, Wang T, Chen J, Kefalov VJ. The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction. Scientific Reports. 6: 32521. PMID 27580676 DOI: 10.1038/Srep32521  0.348
2016 Berry J, Frederiksen R, Yao Y, Nymark S, Chen J, Cornwall C. Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6973-87. PMID 27358455 DOI: 10.1523/Jneurosci.3544-15.2016  0.48
2015 Vinberg F, Wang T, Molday RS, Chen J, Kefalov VJ. A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease. Human Molecular Genetics. PMID 26246500 DOI: 10.1093/Hmg/Ddv319  0.391
2015 Azevedo AW, Doan T, Moaven H, Sokal I, Baameur F, Vishnivetskiy SA, Homan KT, Tesmer JJ, Gurevich VV, Chen J, Rieke F. C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor. Elife. 4. PMID 25910054 DOI: 10.7554/Elife.05981  0.749
2015 Sakurai K, Chen J, Khani SC, Kefalov VJ. Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase. The Journal of Biological Chemistry. 290: 9239-50. PMID 25673692 DOI: 10.1074/Jbc.M115.639591  0.423
2015 Azevedo AW, Doan T, Moaven H, Sokal I, Baameur F, Vishnivetskiy SA, Homan KT, Tesmer JJ, Gurevich VV, Chen J, Rieke F. Author response: C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor Elife. DOI: 10.7554/Elife.05981.018  0.731
2014 Wang T, Chen J. Induction of the unfolded protein response by constitutive G-protein signaling in rod photoreceptor cells. The Journal of Biological Chemistry. 289: 29310-21. PMID 25183010 DOI: 10.1074/Jbc.M114.595207  0.447
2014 Hoyo NL, López-Begines S, Rosa JL, Chen J, Méndez A. Functional EF-hands in neuronal calcium sensor GCAP2 determine its phosphorylation state and subcellular distribution in vivo, and are essential for photoreceptor cell integrity. Plos Genetics. 10: e1004480. PMID 25058152 DOI: 10.1371/Journal.Pgen.1004480  0.428
2013 Song X, Seo J, Baameur F, Vishnivetskiy SA, Chen Q, Kook S, Kim M, Brooks EK, Altenbach C, Hong Y, Hanson SM, Palazzo MC, Chen J, Hubbell WL, Gurevich EV, et al. Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant. Cellular Signalling. 25: 2613-24. PMID 24012956 DOI: 10.1016/J.Cellsig.2013.08.022  0.426
2013 Moaven H, Koike Y, Jao CC, Gurevich VV, Langen R, Chen J. Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina. Proceedings of the National Academy of Sciences of the United States of America. 110: 9463-8. PMID 23690606 DOI: 10.1073/Pnas.1301126110  0.759
2013 Mao W, Miyagishima KJ, Yao Y, Soreghan B, Sampath AP, Chen J. Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity. The Journal of Biological Chemistry. 288: 5257-67. PMID 23288843 DOI: 10.1074/Jbc.M112.430058  0.653
2012 Ruggiero L, Connor MP, Chen J, Langen R, Finnemann SC. Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina. Proceedings of the National Academy of Sciences of the United States of America. 109: 8145-8. PMID 22566632 DOI: 10.1073/Pnas.1121101109  0.412
2012 Tsang SH, Woodruff ML, Lin CS, Jacobson BD, Naumann MC, Hsu CW, Davis RJ, Cilluffo MC, Chen J, Fain GL. Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling. Cellular Signalling. 24: 181-8. PMID 21920434 DOI: 10.1016/J.Cellsig.2011.08.021  0.375
2011 Cleghorn WM, Tsakem EL, Song X, Vishnivetskiy SA, Seo J, Chen J, Gurevich EV, Gurevich VV. Progressive reduction of its expression in rods reveals two pools of arrestin-1 in the outer segment with different roles in photoresponse recovery. Plos One. 6: e22797. PMID 21818392 DOI: 10.1371/Journal.Pone.0022797  0.383
2011 Sakurai K, Chen J, Kefalov VJ. Role of guanylyl cyclase modulation in mouse cone phototransduction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7991-8000. PMID 21632921 DOI: 10.1523/Jneurosci.6650-10.2011  0.391
2011 Blakeley LR, Chen C, Chen CK, Chen J, Crouch RK, Travis GH, Koutalos Y. Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation. Investigative Ophthalmology & Visual Science. 52: 3483-91. PMID 21398289 DOI: 10.1167/Iovs.10-6694  0.424
2011 Song X, Vishnivetskiy SA, Seo J, Chen J, Gurevich EV, Gurevich VV. Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health. Neuroscience. 174: 37-49. PMID 21075174 DOI: 10.1016/J.Neuroscience.2010.11.009  0.411
2010 Chen J, Woodruff ML, Wang T, Concepcion FA, Tranchina D, Fain GL. Channel modulation and the mechanism of light adaptation in mouse rods. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16232-40. PMID 21123569 DOI: 10.1523/Jneurosci.2868-10.2010  0.755
2010 Concepcion F, Chen J. Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration. Plos One. 5: e10904. PMID 20532191 DOI: 10.1371/Journal.Pone.0010904  0.794
2009 Song X, Vishnivetskiy SA, Gross OP, Emelianoff K, Mendez A, Chen J, Gurevich EV, Burns ME, Gurevich VV. Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation. Current Biology : Cb. 19: 700-5. PMID 19361994 DOI: 10.1016/J.Cub.2009.02.065  0.462
2009 Song X, Vishnivetskiy SA, Gross OP, Emelianoff K, Mendez A, Chen J, Gurevich EV, Burns ME, Gurevich VV. Enhanced Arrestin Facilitates Recovery and Protects Rods Lacking Rhodopsin Phosphorylation (DOI:10.1016/j.cub.2009.02.065) Current Biology. 19: 798. DOI: 10.1016/J.Cub.2009.04.050  0.351
2008 Jao CC, Hegde BG, Chen J, Haworth IS, Langen R. Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement. Proceedings of the National Academy of Sciences of the United States of America. 105: 19666-71. PMID 19066219 DOI: 10.1073/Pnas.0807826105  0.353
2008 Shin TM, Isas JM, Hsieh CL, Kayed R, Glabe CG, Langen R, Chen J. Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin. Molecular Neurodegeneration. 3: 16. PMID 18939994 DOI: 10.1186/1750-1326-3-16  0.316
2007 Shi G, Yau KW, Chen J, Kefalov VJ. Signaling properties of a short-wave cone visual pigment and its role in phototransduction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10084-93. PMID 17881515 DOI: 10.1523/Jneurosci.2211-07.2007  0.417
2007 Chen M, Margittai M, Chen J, Langen R. Investigation of alpha-synuclein fibril structure by site-directed spin labeling. The Journal of Biological Chemistry. 282: 24970-9. PMID 17573347 DOI: 10.1074/Jbc.M700368200  0.331
2007 Chan S, Rubin WW, Mendez A, Liu X, Song X, Hanson SM, Craft CM, Gurevich VV, Burns ME, Chen J. Functional comparisons of visual arrestins in rod photoreceptors of transgenic mice. Investigative Ophthalmology & Visual Science. 48: 1968-75. PMID 17460248 DOI: 10.1167/Iovs.06-1287  0.705
2007 Imai H, Kefalov V, Sakurai K, Chisaka O, Ueda Y, Onishi A, Morizumi T, Fu Y, Ichikawa K, Nakatani K, Honda Y, Chen J, Yau KW, Shichida Y. Molecular properties of rhodopsin and rod function. The Journal of Biological Chemistry. 282: 6677-84. PMID 17194706 DOI: 10.1074/Jbc.M610086200  0.363
2006 Chen J, Shi G, Concepcion FA, Xie G, Oprian D. Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa Journal of Neuroscience. 26: 11929-11937. PMID 17108167 DOI: 10.1523/Jneurosci.3212-06.2006  0.761
2006 Doan T, Mendez A, Detwiler PB, Chen J, Rieke F. Multiple phosphorylation sites confer reproducibility of the rod's single-photon responses. Science (New York, N.Y.). 313: 530-3. PMID 16873665 DOI: 10.1126/Science.1126612  0.414
2006 Luibl V, Isas JM, Kayed R, Glabe CG, Langen R, Chen J. Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. The Journal of Clinical Investigation. 116: 378-85. PMID 16453022 DOI: 10.1172/Jci25843  0.302
2006 Burns ME, Mendez A, Chen CK, Almuete A, Quillinan N, Simon MI, Baylor DA, Chen J. Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1036-44. PMID 16421323 DOI: 10.1523/Jneurosci.3301-05.2006  0.445
2005 Shi GW, Chen J, Concepcion F, Motamedchaboki K, Marjoram P, Langen R, Chen J. Light causes phosphorylation of nonactivated visual pigments in intact mouse rod photoreceptor cells. The Journal of Biological Chemistry. 280: 41184-91. PMID 16219764 DOI: 10.1074/Jbc.M506935200  0.771
2005 Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ. Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions. Neuron. 46: 555-67. PMID 15944125 DOI: 10.1016/J.Neuron.2005.03.023  0.406
2005 Sampath AP, Strissel KJ, Elias R, Arshavsky VY, McGinnis JF, Chen J, Kawamura S, Rieke F, Hurley JB. Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron. 46: 413-20. PMID 15882641 DOI: 10.1016/J.Neuron.2005.04.006  0.404
2004 Jao CC, Der-Sarkissian A, Chen J, Langen R. Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling. Proceedings of the National Academy of Sciences of the United States of America. 101: 8331-6. PMID 15155902 DOI: 10.1073/Pnas.0400553101  0.726
2003 Der-Sarkissian A, Jao CC, Chen J, Langen R. Structural organization of alpha-synuclein fibrils studied by site-directed spin labeling. The Journal of Biological Chemistry. 278: 37530-5. PMID 12815044 DOI: 10.1074/Jbc.M305266200  0.723
2003 Mendez A, Lem J, Simon M, Chen J. Light-dependent translocation of arrestin in the absence of rhodopsin phosphorylation and transducin signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3124-9. PMID 12716919  0.352
2003 Mendez A, Lem J, Simon M, Chen J. Light-Dependent Translocation of Arrestin in the Absence of Rhodopsin Phosphorylation and Transducin Signaling The Journal of Neuroscience. 23: 3124-3129. DOI: 10.1523/Jneurosci.23-08-03124.2003  0.457
2002 Mendez A, Chen J. Mouse models to study GCAP functions in intact photoreceptors. Advances in Experimental Medicine and Biology. 514: 361-88. PMID 12596933 DOI: 10.1007/978-1-4615-0121-3_22  0.405
2002 Burns ME, Mendez A, Chen J, Baylor DA. Dynamics of cyclic GMP synthesis in retinal rods. Neuron. 36: 81-91. PMID 12367508 DOI: 10.1016/S0896-6273(02)00911-X  0.4
2002 Concepcion F, Mendez A, Chen J. The carboxyl-terminal domain is essential for rhodopsin transport in rod photoreceptors. Vision Research. 42: 417-26. PMID 11853757 DOI: 10.1016/S0042-6989(01)00195-X  0.763
2002 Lyubarsky AL, Lem J, Chen J, Falsini B, Iannaccone A, Pugh EN. Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy. Vision Research. 42: 401-15. PMID 11853756 DOI: 10.1016/S0042-6989(01)00214-0  0.379
2001 Mendez A, Burns ME, Sokal I, Dizhoor AM, Baehr W, Palczewski K, Baylor DA, Chen J. Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 98: 9948-53. PMID 11493703 DOI: 10.1073/Pnas.171308998  0.436
2001 Hurley JB, Chen J. Evaluation of the contributions of recoverin and GCAPs to rod photoreceptor light adaptation and recovery to the dark state Progress in Brain Research. 131: 395-405. PMID 11420958 DOI: 10.1016/S0079-6123(01)31032-4  0.319
2000 Mendez A, Burns ME, Roca A, Lem J, Wu LW, Simon MI, Baylor DA, Chen J. Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron. 28: 153-64. PMID 11086991 DOI: 10.1016/S0896-6273(00)00093-3  0.428
2000 Mendez A, Krasnoperova NV, Lem J, Chen J. Functional study of rhodopsin phosphorylation in vivo. Methods in Enzymology. 316: 167-85. PMID 10800675 DOI: 10.1016/S0076-6879(00)16723-0  0.449
2000 Nir I, Kedzierski W, Chen J, Travis GH. Expression of Bcl-2 Protects against Photoreceptor Degeneration in retinal degeneration slow (rds) Mice The Journal of Neuroscience. 20: 2150-2154. DOI: 10.1523/Jneurosci.20-06-02150.2000  0.402
1999 Chen CK, Burns ME, Spencer M, Niemi GA, Chen J, Hurley JB, Baylor DA, Simon MI. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 3718-22. PMID 10097103 DOI: 10.1073/Pnas.96.7.3718  0.446
1997 Xu J, Dodd RL, Makino CL, Simon MI, Baylor DA, Chen J. Prolonged photoresponses in transgenic mouse rods lacking arrestin. Nature. 389: 505-9. PMID 9333241 DOI: 10.1038/39068  0.435
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