Marcell R. Smith, Ph.D. - Publications

Affiliations: 
2004 University of Houston, Houston, TX, United States 
Area:
Administration, Nursing, Education

340 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Smith MR, Thomas S, Gormley M, Chowdhury S, Olmos D, Oudard SM, Feng FY, Rajpurohit Y, Urtishak KA, Ricci DS, Rooney OB, Lopez-Gitlitz A, Yu MK, Wyatt AW, Li M, et al. Blood Biomarker Landscape in Patients with High-Risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34112710 DOI: 10.1158/1078-0432.CCR-21-0358  0.484
2021 Feng FY, Thomas S, Saad F, Gormley M, Yu MK, Ricci DS, Rooney B, Brookman-May S, McCarthy S, Olmos D, Chowdhury S, Hadaschik B, Liu Y, Davicioni E, Smith MR, et al. Association of Molecular Subtypes With Differential Outcome to Apalutamide Treatment in Nonmetastatic Castration-Resistant Prostate Cancer. Jama Oncology. PMID 34081076 DOI: 10.1001/jamaoncol.2021.1463  0.513
2020 Uemura H, Satoh T, Tsumura H, Arai G, Imanaka K, Shibayama K, Fujii K, Rooney B, Lopez-Gitlitz A, Espina B, Perez-Ruixo C, Small EJ, Smith M. Efficacy and safety of apalutamide in Japanese patients with nonmetastatic castration-resistant prostate cancer: a subgroup analysis of a randomized, double-blind, placebo-controlled, Phase-3 study. Prostate International. 8: 190-197. PMID 33425798 DOI: 10.1016/j.prnil.2020.05.002  0.534
2020 Uemura H, Matsushima H, Kobayashi K, Mizusawa H, Nishimatsu H, Fizazi K, Smith M, Shore N, Tammela T, Tabata KI, Matsubara N, Iinuma M, Uemura H, Oya M, Momma T, et al. Efficacy and safety of darolutamide in Japanese patients with nonmetastatic castration-resistant prostate cancer: a sub-group analysis of the phase III ARAMIS trial. International Journal of Clinical Oncology. PMID 33226524 DOI: 10.1007/s10147-020-01824-5  0.488
2020 Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, De Porre P, Smith AA, Brookman-May SD, Li S, Zhang K, et al. Apalutamide and Overall Survival in Prostate Cancer. European Urology. PMID 32907777 DOI: 10.1016/J.Eururo.2020.08.011  0.522
2020 Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Le Berre MA, Petrenciuc O, Snapir A, Sarapohja T, Smith MR, et al. Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide. The New England Journal of Medicine. 383: 1040-1049. PMID 32905676 DOI: 10.1056/NEJMoa2001342  0.469
2020 Perez-Ruixo C, Ackaert O, Ouellet D, Chien C, Uemura H, Olmos D, Mainwaring P, Lee JY, Yu MK, Perez Ruixo JJ, Smith MR, Small EJ. Efficacy and safety exposure-response relationships of apalutamide in patients with non-metastatic castration-resistant prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32561663 DOI: 10.1158/1078-0432.CCR-20-1041  0.463
2020 Gillessen S, Attard G, Beer TM, Beltran H, Bjartell A, Bossi A, Briganti A, Bristow RG, Chi KN, Clarke N, Davis ID, de Bono J, Drake CG, Duran I, Eeles R, ... Smith M, et al. Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019. European Urology. PMID 32001144 DOI: 10.1016/J.Eururo.2020.01.012  0.643
2020 Higano CS, Saad F, Sartor AO, Miller K, Conti P, George DJ, Sternberg CN, Shore ND, Sade JP, Bellmunt J, Smith MR, Logothetis C, Verholen F, Kalinovsky J, Bayh I, et al. Clinical outcomes and patient (pt) profiles in REASSURE: An observational study of radium-223 (Ra-223) in metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 38: 32-32. DOI: 10.1200/Jco.2020.38.6_Suppl.32  0.354
2020 Smith MR, Fizazi K, Sandhu SK, Kelly WK, Efstathiou E, Lara P, Yu EY, George DJ, Chi KN, Saad F, Summa J, Freedman JM, Mason G, Espina BM, Zhu E, et al. Niraparib in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and biallelic DNA-repair gene defects (DRD): Correlative measures of tumor response in phase II GALAHAD study. Journal of Clinical Oncology. 38: 118-118. DOI: 10.1200/Jco.2020.38.6_Suppl.118  0.35
2020 Smith MR, Agarwal N, Todenhöfer T, Trepiakas R, Lee J, Lithio A, Chapman S, Nacerddine K, Sweeney C. CYCLONE 2: A phase II, randomized, placebo-controlled study of abiraterone acetate plus prednisone with or without abemaciclib in patients with metastatic castration-resistant prostate cancer. Journal of Clinical Oncology. 38: TPS5591-TPS5591. DOI: 10.1200/jco.2020.38.15_suppl.tps5591  0.447
2020 Chi KN, Rathkopf DE, Attard G, Smith MR, Efstathiou E, Olmos D, Small EJ, Lee JY, Ricci DS, Simon JS, Zhao X, Kothari N, Cheng S, Sandhu SK. A phase III randomized, placebo-controlled, double-blind study of niraparib plus abiraterone acetate and prednisone versus abiraterone acetate and prednisone in patients with metastatic prostate cancer (MAGNITUDE). Journal of Clinical Oncology. 38: TPS5588-TPS5588. DOI: 10.1200/JCO.2020.38.15_SUPPL.TPS5588  0.309
2020 Attard G, Gormley M, Urtishak K, Simon JS, Ricci DS, Parekh TV, Cheng S, Chi KN, Smith MR. Association of detectable levels of circulating tumor DNA (ctDNA) with disease burden in prostate cancer (PC). Journal of Clinical Oncology. 38: 5562-5562. DOI: 10.1200/jco.2020.38.15_suppl.5562  0.321
2020 Chi KN, Saad F, Chowdhury S, Graff JN, Agarwal N, Oudard S, Li G, Lopez-Gitlitz A, Larsen JS, McCarthy SA, Mundle S, Smith MR, Small EJ. Prostate-specific antigen (PSA) kinetics in patients (pts) with advanced prostate cancer treated with apalutamide: Results from the TITAN and SPARTAN studies. Journal of Clinical Oncology. 38: 5541-5541. DOI: 10.1200/Jco.2020.38.15_Suppl.5541  0.414
2020 Saad F, Graff JN, Hadaschik BA, Oudard S, Mainwaring PN, Bhaumik A, Gormley M, Londhe A, Thomas S, Lopez-Gitlitz A, Mundle S, Davicioni E, Small EJ, Smith MR, Feng FY. Molecular determinants of prostate specific antigen (PSA) kinetics and clinical response to apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) in SPARTAN. Journal of Clinical Oncology. 38: 5521-5521. DOI: 10.1200/Jco.2020.38.15_Suppl.5521  0.527
2020 Small EJ, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, De Porre P, Smith A, Brookman-May SD, Li S, Zhang K, ... ... Smith MR, et al. Final survival results from SPARTAN, a phase III study of apalutamide (APA) versus placebo (PBO) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 38: 5516-5516. DOI: 10.1200/Jco.2020.38.15_Suppl.5516  0.315
2020 Fizazi K, Shore ND, Tammela T, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Le Berre M, Petrenciuc O, Snapir A, Sarapohja T, Smith MR. Overall survival (OS) results of phase III ARAMIS study of darolutamide (DARO) added to androgen deprivation therapy (ADT) for nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 38: 5514-5514. DOI: 10.1200/jco.2020.38.15_suppl.5514  0.337
2020 Mateo J, McKay R, Abida W, Aggarwal R, Alumkal J, Alva A, Feng F, Gao X, Graff J, Hussain M, Karzai F, Montgomery B, Oh W, Patel V, Rathkopf D, ... Smith M, et al. Accelerating precision medicine in metastatic prostate cancer Nature Cancer. 1: 1041-1053. DOI: 10.1038/s43018-020-00141-0  0.557
2019 Smith MR, Mehra M, Nair S, Lawson J, Small EJ. Relationship Between Metastasis-free Survival and Overall Survival in Patients With Nonmetastatic Castration-resistant Prostate Cancer. Clinical Genitourinary Cancer. PMID 31980408 DOI: 10.1016/j.clgc.2019.10.030  0.496
2019 Shore N, Zurth C, Fricke R, Gieschen H, Graudenz K, Koskinen M, Ploeger B, Moss J, Prien O, Borghesi G, Petrenciuc O, Tammela TL, Kuss I, Verholen F, Smith MR, et al. Evaluation of Clinically Relevant Drug-Drug Interactions and Population Pharmacokinetics of Darolutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer: Results of Pre-Specified and Post Hoc Analyses of the Phase III ARAMIS Trial. Targeted Oncology. PMID 31571095 DOI: 10.1007/s11523-019-00674-0  0.399
2019 Fendler WP, Weber M, Iravani A, Hofman MS, Calais J, Czernin J, Ilhan H, Saad F, Small EJ, Smith MR, Perez PM, Hope TA, Rauscher I, Londhe A, Lopez-Gitlitz A, et al. Prostate-Specific Membrane Antigen Ligand Positron-Emission Tomography in Men with Nonmetastatic Castration-Resistant Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31511295 DOI: 10.1158/1078-0432.Ccr-19-1050  0.515
2019 Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR. Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer. The New England Journal of Medicine. PMID 30763142 DOI: 10.1056/NEJMoa1815671  0.548
2019 Smith M, Parker C, Saad F, Miller K, Tombal B, Ng QS, Boegemann M, Matveev V, Piulats JM, Zucca LE, Karyakin O, Kimura G, Matsubara N, Nahas WC, Nolè F, et al. Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. Oncology. PMID 30738780 DOI: 10.1016/S1470-2045(18)30860-X  0.53
2019 Feng FY, Thomas S, Gormley M, Lopez-Gitlitz A, Yu MK, Cheng S, Ricci DS, Rooney OB, Mainwaring PN, Olmos D, Saad F, Chowdhury S, Hadaschik BA, Fishbane N, Davicioni E, ... ... Smith MR, et al. Identifying molecular determinants of response to apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) in the SPARTAN trial. Journal of Clinical Oncology. 37: 42-42. DOI: 10.1200/Jco.2019.37.7_Suppl.42  0.331
2019 Small EJ, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, Lopez-Gitlitz A, Espina BM, Shu Y, Rackoff WR, Rooney OB, ... Smith MR, et al. Updated analysis of progression-free survival with first subsequent therapy (PFS2) and safety in the SPARTAN study of apalutamide (APA) in patients (pts) with high-risk nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 37: 144-144. DOI: 10.1200/Jco.2019.37.7_Suppl.144  0.444
2019 Scher HI, Mccormack RT, Molina A, Smith MR, Dreicer R, Saad F, Wit RD, Fizazi K, Aftab DT, Limon A, Fleisher M, Bono JSD, Kelloff GJ, Heller G. Assessment of circulating tumor cell number as a transitional surrogate endpoint for survival in phase II trials for metastatic castration-resistant prostate cancer. Journal of Clinical Oncology. 37: 143-143. DOI: 10.1200/Jco.2019.37.7_Suppl.143  0.344
2019 Fizazi K, Shore ND, Tammela T, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev BY, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR. ARAMIS: Efficacy and safety of darolutamide in nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 37: 140-140. DOI: 10.1200/JCO.2019.37.7_SUPPL.140  0.377
2019 Pollock YG, Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Olmos D, Mainwaring PN, Lee JY, Uemura H, Bhaumik A, Londhe A, Rooney OB, Lopez-Gitlitz A, Mundle S, et al. Predictors of falls and fractures in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) treated with apalutamide (APA) plus ongoing androgen deprivation therapy (ADT). Journal of Clinical Oncology. 37: 5025-5025. DOI: 10.1200/Jco.2019.37.15_Suppl.5025  0.452
2019 Graff JN, Smith MR, Saad F, Hadaschik BA, Uemura H, Lee JY, Mainwaring PN, Olmos D, Oudard S, Londhe A, Bhaumik A, Rooney OB, Lopez-Gitlitz A, Small EJ. Age-related efficacy and safety of apalutamide (APA) plus ongoing androgen deprivation therapy (ADT) in subgroups of patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC): Post hoc analysis of SPARTAN Journal of Clinical Oncology. 37: 5024-5024. DOI: 10.1200/Jco.2019.37.15_Suppl.5024  0.454
2019 Small EJ, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, Lopez-Gitlitz A, Londhe A, Bhaumik A, Cheng S, Rooney OB, Smith MR, et al. Efficacy of apalutamide (APA) plus ongoing androgen deprivation therapy (ADT) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) and baseline (BL) comorbidities (CM). Journal of Clinical Oncology. 37: 5023-5023. DOI: 10.1200/Jco.2019.37.15_Suppl.5023  0.474
2019 Feng F, Thomas S, Gormley M, Lopez-Gitlitz A, Yu MK, Cheng S, Ricci DS, Rooney B, Mainwaring PN, Olmos D, Saad F, Chowdhury S, Hadaschik B, Fishbane N, Davicioni E, ... ... Smith MR, et al. Abstract CT129: Identifying molecular determinants of response to apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) in the SPARTAN study Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct129  0.417
2019 Shore* ND, Smith MR, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Le Berre MA, Snapir A, Sarapohja T, Fizazi K. LBA-09 DAROLUTAMIDE DELAYS PROSTATE-SPECIFIC ANTIGEN PROGRESSION AND TIME TO NEXT ANTICANCER THERAPIES IN PATIENTS WITH NONMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER Journal of Urology. 201. DOI: 10.1097/01.JU.0000557501.15711.19  0.539
2019 Hadaschik BA, Saad F, Graff JN, Olmos D, Oudard S, Mainwaring PN, Uemura H, Lee JY, Lopez-Gitlitz A, Bhaumik A, Londhe A, Cheng S, Todd MB, Small EJ, Smith MR. Mp34-19 Efficacy And Safety Of Apalutamide (Apa) In Nonmetastatic Castration-Resistant Prostate Cancer (Nmcrpc) Patients (Pts) With Or Without Prior Radical Prostatectomy (Rp) And/Or External Radiotherapy (Xrt): Post Hoc Analysis Of Spartan The Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555933.20995.42  0.489
2019 Graff JN, Saad F, Hadaschik BA, Mainwaring PN, Uemura H, Chowdhury S, Oudard S, Olmos D, Lee JY, Lopez-Gitlitz A, Bhaumik A, Londhe A, Cheng S, Todd MB, Smith MR, et al. Mp34-20 Metastasis-Free Survival (Mfs) In Nonmetastatic Castration-Resistant Prostate Cancer (Nmcrpc) Patients (Pts) With Prostate-Specific Antigen (Psa) Decline To < 0.2 Ng/Ml Following Apalutamide (Apa) Treatment: Post Hoc Results From The Phase 3 Spartan Study The Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555927.90500.B0  0.521
2019 Hadaschik* B, Weber M, Iravani A, Hofman MS, Calais J, Czernin J, Ilhan H, Saad F, Small EJ, Smith MR, Perez PM, Hope TA, Rauscher I, Londhe A, Lopez-Gitlitz A, et al. PD17-09 PROSTATE-SPECIFIC MEMBRANE ANTIGEN POSITRON EMISSION TOMOGRAPHY (PSMA-PET) IN HIGH-RISK NONMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER (NMCRPC) SPARTAN-LIKE PATIENTS (PTS) NEGATIVE BY CONVENTIONAL IMAGING Journal of Urology. 201. DOI: 10.1097/01.JU.0000555569.70342.60  0.43
2019 Saad* F, Thomas S, Feng FY, Gormley M, Lopez-Gitlitz A, Yu MK, Cheng S, Ricci DS, Rooney OB, Mainwaring PN, Olmos D, Chowdhury S, Hadaschik BA, Fishbane N, Davicioni E, ... ... Smith MR, et al. PD11-03 RESPONSE TO APALUTAMIDE (APA) AMONG PATIENTS (PTS) WITH NONMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER (NMCRPC) FROM SPARTAN BY DECIPHER GENOMIC CLASSIFIER (GC) SCORE Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555359.59547.3E  0.396
2019 Chi K, Rathkopf D, Attard G, Smith M, Efstathiou E, Olmos D, Small E, Lee J, Sieber P, Dunshee C, Ricci D, Simon J, Zhao X, Kothari N, Cheng S, et al. A phase III randomized, placebo-controlled, double-blind study of niraparib plus abiraterone acetate and prednisone versus abiraterone acetate and prednisone in patients with metastatic prostate cancer (NCT03748641) Annals of Oncology. 30: v354. DOI: 10.1093/annonc/mdz248.054  0.489
2019 Hadaschik B, Weber M, Iravani A, Hofman MS, Calais J, Czernin J, Ilhan H, Saad F, Small EJ, Smith MR, Perez PM, Hope TA, Rauscher I, Londhe A, Lopez-Gitlitz A, et al. Prostate-specific membrane antigen positron-emission tomography (PSMA-PET) in high-risk nonmetastatic castration-resistant prostate cancer (nmCRPC) SPARTAN-like patients (pts) negative by conventional imaging European Urology Supplements. 18. DOI: 10.1016/S1569-9056(19)30510-X  0.397
2018 Smith MR, Parker CC, Saad F, Miller K, Tombal B, Ng QS, Bögemann M, Matveev V, Piulats JM, Zucca LE, Heidenreich A, Kakehi Y, Zhang A, Krissel H, Shen J, et al. ERA 223: A phase III trial of radium-223 (Ra-223) in combination with abiraterone acetate and prednisone/prednisolone for the treatment of asymptomatic or mildly symptomatic chemotherapy-naïve patients (pts) with bone-predominant metastatic castration-resistant prostate cancer (mCRPC). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii723. PMID 32137997 DOI: 10.1093/Annonc/Mdy424.035  0.458
2018 Smith MR, Perez-Ruixo C, Ackaert O, Ouellet D, Chien C, Uemura H, Olmos D, Mainwaring PN, Lee JY, Yu MK, Perez-Ruixo JJ, Small EJ. Relationship between apalutamide (APA) exposure and metastasis-free survival (MFS) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) from SPARTAN. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii278. PMID 32136638 DOI: 10.1093/annonc/mdy284.015  0.466
2018 Small EJ, Cella D, McQuarrie K, Saad F, Hadaschik BA, Graff JN, Uemura H, Oudard S, Yu MK, Hudgens S, Lopez-Gitlitz A, Rooney B, Morris M, Smith MR. Health-related quality of life (HRQoL) after progressive disease (PD) in SPARTAN: A phase III trial of apalutamide (APA) versus placebo (PBO) in men with nonmetastatic castration-resistant prostate cancer (nmCRPC). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii276-viii277. PMID 32136633 DOI: 10.1093/Annonc/Mdy284.013  0.383
2018 Sonpavde GP, Pond GR, Fizazi K, de Bono JS, Basch EM, Scher HI, Smith MR. Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials. European Urology Oncology. PMID 31412002 DOI: 10.1016/j.euo.2018.11.006  0.436
2018 Saad F, Cella D, Basch E, Hadaschik BA, Mainwaring PN, Oudard S, Graff JN, McQuarrie K, Li S, Hudgens S, Lawson J, Lopez-Gitlitz A, Yu MK, Smith MR, Small EJ. Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial. The Lancet. Oncology. PMID 30213449 DOI: 10.1016/S1470-2045(18)30456-X  0.462
2018 Fizazi K, Smith MR, Tombal B. Clinical Development of Darolutamide: A Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer. Clinical Genitourinary Cancer. PMID 30197098 DOI: 10.1016/j.clgc.2018.07.017  0.548
2018 Mateo J, Fizazi K, Gillessen S, Heidenreich A, Perez-Lopez R, Oyen WJG, Shore N, Smith M, Sweeney C, Tombal B, Tomlins SA, de Bono JS. Managing Nonmetastatic Castration-resistant Prostate Cancer. European Urology. PMID 30119985 DOI: 10.1016/j.eururo.2018.07.035  0.538
2018 Smith MR. Progress in Nonmetastatic Prostate Cancer. The New England Journal of Medicine. 378: 2531-2532. PMID 29949488 DOI: 10.1056/NEJMe1805733  0.562
2018 Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, Lopez-Gitlitz A, Trudel GC, Espina BM, Shu Y, Park YC, et al. Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer. The New England Journal of Medicine. PMID 29420164 DOI: 10.1056/Nejmoa1715546  0.501
2018 Miyamoto DT, Lee RJ, Kalinich M, LiCausi J, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, ... Smith MR, et al. An RNA-based digital circulating tumor cell signature is predictive of drug response and early dissemination in prostate cancer. Cancer Discovery. PMID 29301747 DOI: 10.1158/2159-8290.Cd-16-1406  0.541
2018 Smith MR, Saad F, Hussain M, Sternberg CN, Fizazi K, Yamada KS, Kappeler C, Kuss I, Tombal BF. ARASENS: A phase 3 trial of darolutamide in combination with docetaxel for men with metastatic hormone-sensitive prostate cancer (mHSPC). Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.6_Suppl.Tps383  0.457
2018 Small EJ, Saad F, Chowdhury S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Uemura H, Lopez-Gitlitz A, Trudel GC, Espina BM, Shu Y, Park YC, Rackoff WR, Yu MK, Smith MR, et al. SPARTAN, a phase 3 double-blind, randomized study of apalutamide (APA) versus placebo (PBO) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 36: 161-161. DOI: 10.1200/Jco.2018.36.6_Suppl.161  0.404
2018 Small EJ, Saad F, Zheng Y, Pan F, Mehra M, Lawson J, Hadaschik BA, Uemura H, Lee JY, Mainwaring PN, Smith MR. Impact of intervening in high-risk nonmetastatic castration-resistant prostate cancer (HRnmCRPC) on metastatic castration-resistant prostate cancer (mCRPC) disease burden. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E17010  0.532
2018 Small EJ, Saad F, Rathkopf DE, Hadaschik BA, Chowdhury S, Yu MK, Lopez-Gitlitz A, Rooney OB, Shu Y, Darif M, Smith MR. Predicting disease progression in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC): An analysis from the phase 3 SPARTAN trial. Journal of Clinical Oncology. 36: 5034-5034. DOI: 10.1200/Jco.2018.36.15_Suppl.5034  0.509
2018 Smith MR, Saad F, Rathkopf DE, Hadaschik BA, Chowdhury S, Yu MK, Lopez-Gitlitz A, Rooney OB, Darif M, Small EJ. Relationship of time to metastasis (TTM) and site of metastases in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC): Results from the phase 3 SPARTAN trial. Journal of Clinical Oncology. 36: 5033-5033. DOI: 10.1200/Jco.2018.36.15_Suppl.5033  0.43
2018 Smith MR, Mehra M, Nair S, Lawson J, Small EJ. Association of metastasis-free survival (MFS) and overall survival (OS) in nonmetastatic castration-resistant prostate cancer (nmCRPC). Journal of Clinical Oncology. 36: 5032-5032. DOI: 10.1200/JCO.2018.36.15_SUPPL.5032  0.427
2018 Mainwaring P, Small E, Uemura H, Lee J, Pang S, Marx G, Kwon T, Satoh T, Bhaumik A, Cheng S, Londhe A, Lopez-Gitlitz A, Smith M. Efficacy and safety of apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) from SPARTAN: Asian subpopulation Annals of Oncology. 29: ix68. DOI: 10.1093/ANNONC/MDY434.001  0.474
2018 Saad F, Small E, Hadaschik B, Graff J, Mainwaring P, McQuarrie K, Li S, Lawson J, Lopez-Gitlitz A, Smith M. Patient (pt) reported outcomes (PROs) in SPARTAN, a phase 3, double-blind, randomized study of apalutamide (APA) plus androgen deprivation therapy (ADT) vs placebo (PBO) plus ADT in men with nonmetastatic castration-resistant prostate cancer (nmCRPC) European Urology Supplements. 17: e1070-e1071. DOI: 10.1016/S1569-9056(18)31578-1  0.507
2018 Freedland S, Aronson W, Howard L, Smith J, Smith M, Stout J, Allen J, George D, Armstrong A, Inman B, Lin P. PD14-12 SECONDARY OUTCOMES OF A PROSPECTIVE RANDOMIZED TRIAL OF DIETARY CARBOHYDRATE RESTRICTION FOR MEN INITIATING ANDROGEN DEPRIVATION THERAPY: CARBOHYDRATE AND PROSTATE STUDY I (CAPS1) Journal of Urology. 199. DOI: 10.1016/J.JURO.2018.02.798  0.378
2018 Small EJ, Lee JY, Lopez-Gitlitz A, Saad F, Rooney B, Hadaschik BA, Uemura H, Shu Y, Yu M, Smith MR. Pd10-11 Prostate-Specific Antigen (Psa) Outcomes In Patients (Pts) With Nonmetastatic Castration-Resistant Prostate Cancer (Nmcrpc) Treated With Apalutamide (Apa): Results From Phase 3 Spartan Study The Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.621  0.496
2018 Saad F, Mehra M, Small EJ, Lawson J, Dasgupta A, Hadaschik BA, Uemura H, Smith MR. Pd10-04 A Population-Based Study Of The Association Of Prostate-Specific Antigen Doubling Time (Psadt) With Metastasis-Free Survival (Mfs) And Overall Survival (Os) In Nonmetastatic Castration-Resistant Prostate Cancer (Nmcrpc) Patients (Pts) The Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.614  0.465
2018 Small EJ, Saad F, Hadaschik BA, Graff JN, Mainwaring PN, McQuarrie K, Li S, Lawson J, Lopez-Gitlitz A, Smith MR. Mp52-20 Patient Reported Outcomes (Pros) In Spartan, A Phase 3, Double-Blind, Randomized Study Of Apalutamide (Apa) Plus Androgen Deprivation Therapy (Adt) Vs Placebo Plus Adt In Men With Nonmetastatic Castration-Resistant Prostate Cancer (Nmcrpc) The Journal of Urology. 17. DOI: 10.1016/J.Juro.2018.02.1671  0.513
2017 Heller G, McCormack R, Kheoh T, Molina A, Smith MR, Dreicer R, Saad F, de Wit R, Aftab DT, Hirmand M, Limon A, Fizazi K, Fleisher M, de Bono JS, Scher HI. Circulating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017752998. PMID 29272162 DOI: 10.1200/Jco.2017.75.2998  0.452
2017 Sartor O, Vogelzang NJ, Sweeney C, Fernandez DC, Almeida F, Iagaru A, Brown A, Smith MR, Agrawal M, Dicker AP, Garcia JA, Lutzky J, Wong YN, Petrenciuc O, Gratt J, et al. Radium-223 Safety, Efficacy, and Concurrent Use with Abiraterone or Enzalutamide: First U.S. Experience from an Expanded Access Program. The Oncologist. PMID 29183960 DOI: 10.1634/theoncologist.2017-0413  0.333
2017 Tombal B, Borre M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Braeckman J, Heracek J, Baron B, Krivoshik A, Hirmand M, Smith MR. Long-term Anti-tumor Activity and Safety of Enzalutamide Monotherapy in Hormone-naïve Prostate Cancer: 3-year, Open-label, Follow-up Results. The Journal of Urology. PMID 28867562 DOI: 10.1016/j.juro.2017.08.103  0.455
2017 Gillessen S, Attard G, Beer TM, Beltran H, Bossi A, Bristow R, Carver B, Castellano D, Chung BH, Clarke N, Daugaard G, Davis ID, de Bono J, Dos Reis RB, Drake CG, ... Smith M, et al. Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. European Urology. PMID 28655541 DOI: 10.1016/J.Eururo.2017.06.002  0.647
2017 Smith MR, Saad F, Rathkopf DE, Mulders PF, de Bono JS, Small EJ, Shore ND, Fizazi K, Kheoh T, Li J, De Porre P, Todd MB, Yu MK, Ryan CJ. Clinical Outcomes from Androgen Signaling-directed Therapy after Treatment with Abiraterone Acetate and Prednisone in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302. European Urology. PMID 28314611 DOI: 10.1016/J.Eururo.2017.03.007  0.48
2017 Smith MR, Saad F, Hussain M, Sternberg CN, Fizazi K, Crawford ED, Yamada KS, Kappeler C, Kuss I, Tombal BF. ARASENS phase 3 trial of ODM-201 in men with metastatic hormone-sensitive prostate cancer (mHSPC). Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.Tps5092  0.468
2017 Tombal B, Saad F, Hussain M, Sternberg CN, Fizazi K, Crawford ED, Yamada K, Kappeler C, Kuss I, Smith MR. 838TiPARASENS: A phase 3 trial of darolutamide in males with metastatic hormone-sensitive prostate cancer (mHSPC) Annals of Oncology. 28. DOI: 10.1093/Annonc/Mdx370.055  0.486
2017 Smith M, Saad F, Hussain M, Sternberg C, Fizazi K, Crawford D, Yamada K, Kappeler C, Kuss I, Tombal B. A phase 3 randomized, double-blind, placebo-controlled trial of ODM-201 vs. placebo in combination with standard androgen deprivation therapy and docetaxel in patients with metastatic hormone-sensitive prostate cancer (ARASENS) European Urology Supplements. 16. DOI: 10.1016/S1569-9056(17)30272-5  0.465
2016 Fu AZ, Tsai HT, Haque R, Ulcickas Yood M, Cassidy-Bushrow AE, Van Den Eeden SK, Keating NL, Smith MR, Zhou Y, Aaronson DS, Potosky AL. Mortality and Androgen-Deprivation Therapy as Salvage Treatment for Biochemical Recurrence after Primary Therapy for Clinically Localized Prostate Cancer. The Journal of Urology. PMID 28007467 DOI: 10.1016/j.juro.2016.12.086  0.515
2016 de Bono JS, Smith MR, Saad F, Rathkopf DE, Mulders PF, Small EJ, Shore ND, Fizazi K, De Porre P, Kheoh T, Li J, Todd MB, Ryan CJ, Flaig TW. Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302. European Urology. PMID 27402060 DOI: 10.1016/J.Eururo.2016.06.033  0.488
2016 Smith M, De Bono J, Sternberg C, Le Moulec S, Oudard S, De Giorgi U, Krainer M, Bergman A, Hoelzer W, De Wit R, Bögemann M, Saad F, Cruciani G, Vuillemin AT, Feyerabend S, et al. Phase III Study of Cabozantinib in Previously Treated Metastatic Castration-Resistant Prostate Cancer: COMET-1. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27400947 DOI: 10.1200/Jco.2015.65.5597  0.491
2016 Xu XS, Ryan CJ, Stuyckens K, Smith MR, Saad F, Griffin TW, Park YC, Yu MK, De Porre P, Vermeulen A, Poggesi I, Nandy P. Modeling the Relationship Between Exposure to Abiraterone and Prostate-Specific Antigen Dynamics in Patients with Metastatic Castration-Resistant Prostate Cancer. Clinical Pharmacokinetics. PMID 27324190 DOI: 10.1007/S40262-016-0425-0  0.503
2016 Smith MR, Antonarakis ES, Ryan CJ, Berry WR, Shore ND, Liu G, Alumkal JJ, Higano CS, Chow Maneval E, Bandekar R, de Boer CJ, Yu MK, Rathkopf DE. Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort. European Urology. PMID 27160947 DOI: 10.1016/j.eururo.2016.04.023  0.312
2016 Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, et al. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27141017 DOI: 10.1093/Annonc/Mdw180  0.572
2016 Fu AZ, Tsai HT, Haque R, Ulcickas Yood M, Van Den Eeden SK, Cassidy-Bushrow AE, Zhou Y, Keating NL, Smith MR, Aaronson DS, Potosky AL. Use of androgen deprivation therapy as salvage treatment after primary therapy for clinically localized prostate cancer. World Journal of Urology. PMID 27084777 DOI: 10.1007/s00345-016-1823-5  0.481
2016 Voog JC, Smith MR, Efstathiou JA. Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer. Jama. 315: 1054-5. PMID 26954419 DOI: 10.1001/Jama.2015.17567  0.487
2016 Scher HI, Morris MJ, Stadler WM, Higano C, Basch E, Fizazi K, Antonarakis ES, Beer TM, Carducci MA, Chi KN, Corn PG, de Bono JS, Dreicer R, George DJ, Heath EI, ... Smith MR, et al. Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26903579 DOI: 10.1200/Jco.2015.64.2702  0.517
2016 Fizazi K, Shore ND, Tammela TLJ, Sarapohja T, Vuorela A, Kuss I, Snapir A, Smith MR. ARAMIS trial: Efficacy and safety of ODM-201 in men with high-risk nonmetastatic castration-resistant prostate cancer. Journal of Clinical Oncology. 34: TPS5094-TPS5094. DOI: 10.1200/JCO.2016.34.15_SUPPL.TPS5094  0.484
2016 Smith MR, Parker CC, Tombal BF, Miller K, Saad F, Shen J, Zhang A, Kornacker M, Higano CS. ERA 223: A phase 3 trial of radium-223 dichloride in combination with abiraterone acetate and prednisone in the treatment of asymptomatic or mildly symptomatic chemotherapy-naïve patients with bone-predominant metastatic castration-resistant prostate cancer. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.Tps5088  0.395
2016 Sandler HM, McKenzie MR, Tombal BF, Baskin-Bey E, Freedland SJ, Roach M, Widmark A, Bossi A, Dicker A, Wiegel T, Shore ND, Smith MR, Yu MK, Kheoh T, Thomas S, et al. ATLAS: A randomized, double-blind, placebo-controlled, phase 3 trial of apalutamide (ARN-509) in patients with high-risk localized or locally advanced prostate cancer receiving primary radiation therapy. Journal of Clinical Oncology. 34: TPS5087-TPS5087. DOI: 10.1200/JCO.2016.34.15_SUPPL.TPS5087  0.425
2016 Suzuki K, Kuss I, Smith MR, Fizazi K. ARAMIS trial: Efficacy and safety of ODM-201 in men with high-risk nonmetastatic castration-resistant prostate cancer Annals of Oncology. 27: vii106. DOI: 10.1093/annonc/mdw524.007  0.484
2016 Bossi A, Dearnaley D, McKenzie M, Baskin-Bey E, Tyler R, Tombal B, Freedland SJ, I RM,II, Widmark A, Dicker AP, Wiegel T, Shore N, Smith M, Yu M, Kheoh T, et al. ATLAS : A phase 3 trial evaluating the efficacy of apalutamide (ARN-509) in patients with high-risk localized or locally advanced prostate cancer receiving primary radiation therapy Annals of Oncology. 27. DOI: 10.1093/Annonc/Mdw372.52  0.437
2016 Freedland S, Aronson W, Howard L, Smith J, Smith M, Stout J, Allen J, George D, Armstrong A, Inman B, Lin P. MP04-06 A PROSPECTIVE RANDOMIZED TRIAL OF DIETARY CARBOHYDRATE RESTRICTION FOR MEN INITIATING ANDROGEN DEPRIVATION THERAPY: CARBOHYDRATE AND PROSTATE STUDY I (CAPS1) Journal of Urology. 195. DOI: 10.1016/J.JURO.2016.02.1941  0.447
2015 Bellmunt J, Kheoh T, Yu MK, Smith MR, Small EJ, Mulders PF, Fizazi K, Rathkopf DE, Saad F, Scher HI, Taplin ME, Davis ID, Schrijvers D, Protheroe A, Molina A, et al. Prior Endocrine Therapy Impact on Abiraterone Acetate Clinical Efficacy in Metastatic Castration-resistant Prostate Cancer: Post-hoc Analysis of Randomised Phase 3 Studies. European Urology. PMID 26508309 DOI: 10.1016/J.Eururo.2015.10.021  0.528
2015 Miyamoto DT, Zheng Y, Wittner BS, Lee RJ, Zhu H, Broderick KT, Desai R, Fox DB, Brannigan BW, Trautwein J, Arora KS, Desai N, Dahl DM, Sequist LV, Smith MR, et al. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science (New York, N.Y.). 349: 1351-6. PMID 26383955 DOI: 10.1126/Science.Aab0917  0.433
2015 Voog JC, Paulus R, Shipley WU, Smith MR, McGowan DG, Jones CU, Bahary JP, Zeitzer KL, Souhami L, Leibenhaut MH, Rotman M, Husain SM, Gore E, Raben A, Chafe S, et al. Cardiovascular Mortality Following Short-term Androgen Deprivation in Clinically Localized Prostate Cancer: An Analysis of RTOG 94-08. European Urology. PMID 26362090 DOI: 10.1016/J.Eururo.2015.08.027  0.439
2015 Gartrell BA, Coleman R, Efstathiou E, Fizazi K, Logothetis CJ, Smith MR, Sonpavde G, Sartor O, Saad F. Metastatic Prostate Cancer and the Bone: Significance and Therapeutic Options. European Urology. PMID 26153564 DOI: 10.1016/J.Eururo.2015.06.039  0.439
2015 Smith MR, Rathkopf DE, Mulders PF, Carles J, Van Poppel H, Li J, Kheoh T, Griffin TW, Molina A, Ryan CJ. Efficacy and Safety of Abiraterone Acetate in Elderly (≥75 Years) Chemotherapy-Naïve Patients with Metastatic Castration-Resistant Prostate Cancer. The Journal of Urology. PMID 26151676 DOI: 10.1016/j.juro.2015.07.004  0.509
2015 Preston MA, Feldman AS, Coen JJ, McDougal WS, Smith MR, Paly JJ, Carrasquillo R, Wu CL, Dahl DM, Barrisford GW, Blute ML, Zietman AI. Active surveillance for low-risk prostate cancer: Need for intervention and survival at 10 years. Urologic Oncology. PMID 26059076 DOI: 10.1016/j.urolonc.2015.04.015  0.439
2015 Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, et al. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 1589-604. PMID 26041764 DOI: 10.1093/annonc/mdv257  0.563
2015 Saad F, Shore N, Van Poppel H, Rathkopf DE, Smith MR, de Bono JS, Logothetis CJ, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, et al. Impact of Bone-targeted Therapies in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer Patients Treated with Abiraterone Acetate: Post Hoc Analysis of Study COU-AA-302. European Urology. PMID 25985882 DOI: 10.1016/J.Eururo.2015.04.032  0.455
2015 Xu XS, Ryan CJ, Stuyckens K, Smith MR, Saad F, Griffin TW, Park YC, Yu MK, Vermeulen A, Poggesi I, Nandy P. Correlation between Prostate-Specific Antigen Kinetics and Overall Survival in Abiraterone Acetate-Treated Castration-Resistant Prostate Cancer Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3170-7. PMID 25829400 DOI: 10.1158/1078-0432.Ccr-14-1549  0.438
2015 Tombal B, Borre M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Braeckman J, Heracek J, Baskin-Bey E, Ouatas T, Perabo F, Phung, Baron B, Hirmand M, Smith MR, et al. Long-term Efficacy and Safety of Enzalutamide Monotherapy in Hormone-naïve Prostate Cancer: 1- and 2-Year Open-label Follow-up Results. European Urology. PMID 25687533 DOI: 10.1016/j.eururo.2015.01.027  0.561
2015 Ryan CJ, Smith MR, Fizazi K, Saad F, Mulders PF, Sternberg CN, Miller K, Logothetis CJ, Shore ND, Small EJ, Carles J, Flaig TW, Taplin ME, Higano CS, de Souza P, et al. Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study. The Lancet. Oncology. 16: 152-60. PMID 25601341 DOI: 10.1016/S1470-2045(14)71205-7  0.38
2015 Tsai HT, Keating NL, Van Den Eeden SK, Haque R, Cassidy-Bushrow AE, Ulcickas Yood M, Smith MR, Potosky AL. Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer. The Journal of Urology. 193: 1956-62. PMID 25524243 DOI: 10.1016/j.juro.2014.12.027  0.471
2015 Fizazi K, Massard C, Smith M, Rader M, Brown J, Milecki P, Shore N, Oudard S, Karsh L, Carducci M, Damião R, Wang H, Ying W, Goessl C. Bone-related Parameters are the Main Prognostic Factors for Overall Survival in Men with Bone Metastases from Castration-resistant Prostate Cancer. European Urology. 68: 42-50. PMID 25449207 DOI: 10.1016/j.eururo.2014.10.001  0.498
2015 Smith MR, Coleman RE, Klotz L, Pittman K, Milecki P, Ng S, Chi KN, Balakumaran A, Wei R, Wang H, Braun A, Fizazi K. Denosumab for the prevention of skeletal complications in metastatic castration-resistant prostate cancer: comparison of skeletal-related events and symptomatic skeletal events. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 368-74. PMID 25425475 DOI: 10.1093/annonc/mdu519  0.416
2015 Nguyen PL, Alibhai SM, Basaria S, D'Amico AV, Kantoff PW, Keating NL, Penson DF, Rosario DJ, Tombal B, Smith MR. Adverse effects of androgen deprivation therapy and strategies to mitigate them. European Urology. 67: 825-36. PMID 25097095 DOI: 10.1016/j.eururo.2014.07.010  0.411
2015 Basch E, Autio KA, Smith MR, Bennett AV, Weitzman AL, Scheffold C, Sweeney C, Rathkopf DE, Smith DC, George DJ, Higano CS, Harzstark AL, Sartor AO, Gordon MS, Vogelzang NJ, et al. Effects of cabozantinib on pain and narcotic use in patients with castration-resistant prostate cancer: results from a phase 2 nonrandomized expansion cohort. European Urology. 67: 310-8. PMID 24631409 DOI: 10.1016/j.eururo.2014.02.013  0.413
2015 De Bono JS, Smith MR, Saad F, Rathkopf DE, Mulders PF, Small EJ, Shore ND, Fizazi K, De Porre P, Kheoh TS, Li J, Todd MB, Griffin TW, Ryan CJ. Response to taxane chemotherapy as first subsequent therapy after abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Post-hoc analysis of COU-AA-302. Journal of Clinical Oncology. 33: 184-184. DOI: 10.1200/Jco.2015.33.7_Suppl.184  0.33
2015 Smith MR, Bono JSD, Sternberg CN, Moulec SL, Oudard S, Giorgi UD, Krainer M, Bergman AM, Hoelzer W, Wit RD, Boegemann M, Saad F, Cruciani G, Vuillemin AT, Feyerabend S, et al. Final analysis of COMET-1: Cabozantinib (Cabo) versus prednisone (Pred) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) previously treated with docetaxel (D) and abiraterone (A) and/or enzalutamide (E). Journal of Clinical Oncology. 33: 139-139. DOI: 10.1200/Jco.2015.33.7_Suppl.139  0.304
2015 Smith MR, Parker C, Tombal BF, Miller K, Saad F, Fang F, Zhang A, Kornacker M, Higano CS. ERA 223: A phase 3 trial of radium-223 dichloride (Ra-223) in combination with abiraterone acetate (abiraterone) and prednisone in the treatment of asymptomatic or mildly symptomatic chemotherapy-naïve patients (pts) with bone predominant metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 33. DOI: 10.1200/Jco.2015.33.15_Suppl.Tps5082  0.362
2015 Shore ND, Concepcion RS, Smith MR, Pieczonka CM, Nguyen S, Belkoff LH, Firlit R, McCoy C, DeVries T, Freedland SJ. PREDICT, a study evaluating baseline (BL) disease characteristics predictive of a positive imaging study for distant metastases in patients (pts) with castration-resistant prostate cancer (CRPC): Preliminary data. Journal of Clinical Oncology. 33: e16028-e16028. DOI: 10.1200/JCO.2015.33.15_SUPPL.E16028  0.413
2015 Scher HI, Morris MJ, Stadler WM, Higano CS, Halabi S, Smith MR, Basch EM, Fizazi K, Ryan CJ, Antonarakis ES, Corn PG, Liu G, De Bono JS, Schwartz LH, Beer TM, et al. The Prostate Cancer Working Group 3 (PCWG3) consensus for trials in castration-resistant prostate cancer (CRPC). Journal of Clinical Oncology. 33: 5000-5000. DOI: 10.1200/JCO.2015.33.15_SUPPL.5000  0.554
2015 Saad F, Bono JSD, Smith MR, Rathkopf DE, Mulders PFA, Small EJ, Shore ND, Fizazi K, Porre PD, Kheoh T, Li J, Todd MB, Griffin TW, Ryan CJ. 668 Response to taxane chemotherapy as first subsequent therapy after abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC): Post hoc analysis of COU-AA-302 European Urology Supplements. 14. DOI: 10.1016/S1569-9056(15)60661-3  0.512
2015 Mulders PFA, Smith MR, Fizazi K, Saad F, Sternberg CN, Miller K, Logothetis CJ, Shore ND, Small EJ, Carles J, Flaig TW, Taplin M, Higano CS, Souza PD, Bono JSD, et al. 556 Abiraterone acetate improves overall survival in chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC): Impact of crossover and baseline prognostic factors in the COU-AA-302 final analysis European Urology Supplements. 14. DOI: 10.1016/S1569-9056(15)60549-8  0.459
2015 Shore N, Smith MR, Lipton A, Brown JE, Oudard S, Carducci M, Saad F, Damiao R, Zhu L, Warner D, Fizazi K. Mp73-10 Bone Turnover Marker Levels And Outcomes In Men With Prostate Cancer And Bone Metastases Treated With Bone Antiresorptive Agents The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2686  0.368
2015 Shore ND, Antonarakis ES, Ryan CJ, Berry WR, Liu G, Higano C, Chow Maneval E, Bandekar R, de Boer CJ, Todd MB, Yu MK, Rathkopf DE, Smith MR. MP87-16 NOVEL ANTIANDROGEN ARN-509 IN HIGH-RISK NONMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER Journal of Urology. 193. DOI: 10.1016/J.JURO.2015.02.1961  0.499
2015 Gartrell BA, Coleman R, Efstathiou E, Fizazi K, Logothetis CJ, Smith MR, Sonpavde G, Sartor O, Saad F. Metastatic Prostate Cancer and the Bone: Significance and Therapeutic Options European Urology. DOI: 10.1016/j.eururo.2015.06.039  0.534
2014 Smith MR, Sweeney CJ, Corn PG, Rathkopf DE, Smith DC, Hussain M, George DJ, Higano CS, Harzstark AL, Sartor AO, Vogelzang NJ, Gordon MS, de Bono JS, Haas NB, Logothetis CJ, et al. Cabozantinib in chemotherapy-pretreated metastatic castration-resistant prostate cancer: results of a phase II nonrandomized expansion study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 3391-9. PMID 25225437 DOI: 10.1200/JCO.2013.54.5954  0.461
2014 Stuyckens K, Saad F, Xu XS, Ryan CJ, Smith MR, Griffin TW, Yu MK, Vermeulen A, Nandy P, Poggesi I. Population pharmacokinetic analysis of abiraterone in chemotherapy-naïve and docetaxel-treated patients with metastatic castration-resistant prostate cancer. Clinical Pharmacokinetics. 53: 1149-60. PMID 25204404 DOI: 10.1007/S40262-014-0178-6  0.423
2014 Sonpavde G, Pond GR, Armstrong AJ, Clarke SJ, Vardy JL, Templeton AJ, Wang SL, Paolini J, Chen I, Chow-Maneval E, Lechuga M, Smith MR, Michaelson MD. Prognostic impact of the neutrophil-to-lymphocyte ratio in men with metastatic castration-resistant prostate cancer. Clinical Genitourinary Cancer. 12: 317-24. PMID 24806399 DOI: 10.1016/j.clgc.2014.03.005  0.488
2014 Tombal B, Borre M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Braeckman J, Heracek J, Baskin-Bey E, Ouatas T, Perabo F, Phung D, Hirmand M, Smith MR. Enzalutamide monotherapy in hormone-naive prostate cancer: primary analysis of an open-label, single-arm, phase 2 study. The Lancet. Oncology. 15: 592-600. PMID 24739897 DOI: 10.1016/S1470-2045(14)70129-9  0.561
2014 Rathkopf DE, Smith MR, de Bono JS, Logothetis CJ, Shore ND, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, Van Poppel H, Carles J, et al. Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302). European Urology. 66: 815-25. PMID 24647231 DOI: 10.1016/J.Eururo.2014.02.056  0.514
2014 Potosky AL, Haque R, Cassidy-Bushrow AE, Ulcickas Yood M, Jiang M, Tsai HT, Luta G, Keating NL, Smith MR, Van Den Eeden SK. Effectiveness of primary androgen-deprivation therapy for clinically localized prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1324-30. PMID 24638009 DOI: 10.1200/JCO.2013.52.5782  0.483
2014 Smith MR, Halabi S, Ryan CJ, Hussain A, Vogelzang N, Stadler W, Hauke RJ, Monk JP, Saylor P, Bhoopalam N, Saad F, Sanford B, Kelly WK, Morris M, Small EJ. Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1143-50. PMID 24590644 DOI: 10.1200/Jco.2013.51.6500  0.536
2014 Sonpavde G, Pond GR, Armstrong AJ, Galsky MD, Leopold L, Wood BA, Wang SL, Paolini J, Chen I, Chow-Maneval E, Mooney DJ, Lechuga M, Smith MR, Michaelson MD. Radiographic progression by Prostate Cancer Working Group (PCWG)-2 criteria as an intermediate endpoint for drug development in metastatic castration-resistant prostate cancer. Bju International. 114: E25-31. PMID 24298897 DOI: 10.1111/bju.12589  0.561
2014 Lee RJ, Smith MR. Cabozantinib and prostate cancer: inhibiting seed and disrupting soil? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 525-7. PMID 24284057 DOI: 10.1158/1078-0432.Ccr-13-2636  0.472
2014 Keating NL, Liu PH, O'Malley AJ, Freedland SJ, Smith MR. Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer. European Urology. 65: 816-24. PMID 23453420 DOI: 10.1016/j.eururo.2013.02.023  0.358
2014 Saylor PJ, Smith MR, O'Malley AJ, Keating NL. Androgen-deprivation therapy and risk for biliary disease in men with prostate cancer. European Urology. 65: 642-9. PMID 23428068 DOI: 10.1016/j.eururo.2013.02.003  0.456
2014 Tombal B, Borre M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Braeckman J, Heracek J, Baskin-Bey E, Ouatas T, Perabo F, Phung D, Smith MR. Enzalutamide monotherapy: Extended follow-up of a phase II study in hormone-naive prostate cancer patients. Journal of Clinical Oncology. 32: 62-62. DOI: 10.1200/JCO.2014.32.4_SUPPL.62  0.454
2014 Stuyckens K, Saad F, Xu S, Ryan CJ, Smith MR, Griffin TW, Yu MK, Vermeulen A, Nandy P, Poggesi I. Population pharmacokinetic analysis of abiraterone acetate in healthy volunteers and chemotherapy-naive and chemotherapy-pretreated metastatic castration-resistant prostate cancer patients. Journal of Clinical Oncology. 32: 58-58. DOI: 10.1200/Jco.2014.32.4_Suppl.58  0.375
2014 Xu S, Ryan CJ, Stuyckens K, Smith MR, Saad F, Griffin TW, Park YC, Yu MK, Vermeulen A, Poggesi I, Nandy P. Relationship between abiraterone exposure, prostate-specific antigen (PSA) kinetics, and overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) . Journal of Clinical Oncology. 32: 39-39. DOI: 10.1200/Jco.2014.32.4_Suppl.39  0.454
2014 Smith MR, Coleman RE, Klotz L, Pittman KB, Milecki P, Wei R, Balakumaran A, Fizazi K. Denosumab for the prevention of symptomatic skeletal events in patients with castration-resistant advanced prostate cancer: A comparison with skeletal-related events. Journal of Clinical Oncology. 32: 35-35. DOI: 10.1200/JCO.2014.32.4_SUPPL.35  0.337
2014 Yu EY, Saad F, Londhe A, Shore ND, Poppel HV, Rathkopf DE, Smith MR, Logothetis C, Souza PLD, Fizazi K, Mulders PFA, Mainwaring PN, Hainsworth JD, Beer TM, North SA, et al. Association of alkaline phosphatase (ALP) with clinical outcomes in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302. Journal of Clinical Oncology. 32: 27-27. DOI: 10.1200/Jco.2014.32.4_Suppl.27  0.418
2014 Smith MR, Matheny S, Saad F, Rathkopf DE, Mulders PF, De Bono JS, Small EJ, Shore ND, Fizazi K, Kheoh TS, Li J, Todd MB, Griffin TW, Yu MK, Ryan CJ. Response to androgen signaling (AS)-directed therapy after treatment with abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Post hoc analysis of study COU-AA-302. Journal of Clinical Oncology. 32: 21-21. DOI: 10.1200/Jco.2014.32.4_Suppl.21  0.323
2014 Yu EY, Getzenberg RH, Smith J, Hancock ML, Smith MR, Malkowicz SB, Sieber P, Dalton JT, Steiner MS. Optimal testosterone suppression on medical ADT should strive to suppress free testosterone levels to levels similar to orchiectomy: What is that value? Journal of Clinical Oncology. 32: 144-144. DOI: 10.1200/Jco.2014.32.4_Suppl.144  0.314
2014 Oudard S, Kheoh TS, Yu MK, Smith MR, Small EJ, Mulders PFA, Fizazi K, Rathkopf DE, Saad F, Scher HI, Bellmunt J, Taplin M, Davis ID, Schrijvers DL, Protheroe A, et al. Impact of prior endocrine therapy on radiographic progression-free survival (rPFS) in patients (pts) with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302. Journal of Clinical Oncology. 32: 14-14. DOI: 10.1200/Jco.2014.32.4_Suppl.14  0.354
2014 Patrick D, Cleeland CS, Fallowfield L, Smith MR, Klotz L, Oudard S, Marx GM, Wei R, Ohrling K, Qian Y. Denosumab or zoledronic acid (ZA) therapy on pain interference and cancer-specific quality of life (CSQoL) in patients with castrate-resistant prostate cancer (CRPC) and bone metastases (BM). Journal of Clinical Oncology. 32: 12-12. DOI: 10.1200/Jco.2014.32.4_Suppl.12  0.338
2014 Smith MR, Liu G, Shreeve SM, Matheny S, Sosa A, Kheoh TS, Yu MK, Small EJ. A randomized double-blind, comparative study of ARN-509 plus androgen deprivation therapy (ADT) versus ADT alone in nonmetastatic castration-resistant prostate cancer (M0-CRPC): The SPARTAN trial. Journal of Clinical Oncology. 32: TPS5100-TPS5100. DOI: 10.1200/JCO.2014.32.15_SUPPL.TPS5100  0.497
2014 Klotz L, Smith MR, Coleman RE, Pittman KB, Milecki P, Wei R, Balakumaran A, Fizazi K. Symptomatic skeletal events (SSE) in patients with advanced prostate cancer: Results from a phase III trial of denosumab for the prevention of skeletal-related events. Journal of Clinical Oncology. 32: 5075-5075. DOI: 10.1200/JCO.2014.32.15_SUPPL.5075  0.455
2014 Borre M, Smith M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Braeckman J, Heracek J, Baskin-Bey E, Ouatas T, Perabo F, Phung D, Baron B, Hirmand M, et al. P060 Enzalutamide monotherapy in patients with hormone-naive prostate cancer: 1-year extended follow-up of a Phase 2 study European Urology Supplements. 13: 131. DOI: 10.1016/S1569-9056(14)61283-5  0.489
2014 Schrijvers D, Kheoh T, Yu MK, Smith MR, Small EJ, Mulders PF, Fizazi K, Rathkopf D, Saad F, Scher HI, Oudard S, Bellmunt J, Taplin M, Davis ID, Protheroe A, et al. 861 Impact of prior endocrine therapy on radiographic progression-free survival (rPFS) in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer: Results from COU-AA-302 European Urology Supplements. 13. DOI: 10.1016/S1569-9056(14)60848-4  0.501
2014 Patrick D, Smith MR, Fizazi K, Cleeland CS, Fallowfield L, Chi KN, Wei R, Ohrling K, Qian Y. MP78-01 THE BURDEN OF SKELETAL-RELATED EVENTS ON PAIN OUTCOMES IN PATIENTS WITH CASTRATION-RESISTANT PROSTATE CANCER Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.2484  0.435
2014 Shore N, Rathkopf D, Smith MR, de Bono JS, Logothetis C, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, Griffin T, Park YC, et al. PD27-01 EFFICACY AND LONG-TERM SAFETY ANALYSIS OF STUDY COU-AA-302: ABIRATERONE ACETATE PLUS PREDNISONE IN CHEMOTHERAPY-NAÏVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.2100  0.402
2014 Tsai H, Keating NL, Ulcickas Yood M, Van Den Eeden SK, Haque R, Cassidy-Bushrow AE, Smith MR, Potosky AL. Risk of Diabetes Among Patients Exposed to Primary Androgen Deprivation Therapy for Clinically Localized Prostate Cancer Annals of Epidemiology. 24: 682. DOI: 10.1016/J.ANNEPIDEM.2014.06.009  0.464
2013 Borre M, Rathenborg P, Werbrouck P, Heidenreich A, Iversen P, Baskin-Bey ES, Perabo F, Phung, Smith MR. Enzalutamide monotherapy: Phase II study results in patients with hormone-naive prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 18. PMID 28137170 DOI: 10.1200/jco.2013.31.6_suppl.18  0.4
2013 Smith MR, De Bono JS, Logothetis C, Shore ND, De Souza PL, Fizazi K, Mulders P, Mainwaring PN, Hainsworth JD, Beer TM, North SA, Fradet Y, Griffin TW, Park YC, Kheoh TS, et al. Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 5. PMID 28137142 DOI: 10.1200/Jco.2013.31.6_Suppl.5  0.415
2013 Kachnic LA, Pugh SL, Tai P, Smith M, Gore E, Shah AB, Martin AG, Kim HE, Nabid A, Lawton CA. RTOG 0518: randomized phase III trial to evaluate zoledronic acid for prevention of osteoporosis and associated fractures in prostate cancer patients. Prostate Cancer and Prostatic Diseases. 16: 382-6. PMID 24080992 DOI: 10.1038/pcan.2013.35  0.444
2013 Basch E, Autio K, Ryan CJ, Mulders P, Shore N, Kheoh T, Fizazi K, Logothetis CJ, Rathkopf D, Smith MR, Mainwaring PN, Hao Y, Griffin T, Li S, Meyers ML, et al. Abiraterone acetate plus prednisone versus prednisone alone in chemotherapy-naive men with metastatic castration-resistant prostate cancer: patient-reported outcome results of a randomised phase 3 trial. The Lancet. Oncology. 14: 1193-9. PMID 24075621 DOI: 10.1016/S1470-2045(13)70424-8  0.492
2013 Smith MR, Saad F, Oudard S, Shore N, Fizazi K, Sieber P, Tombal B, Damiao R, Marx G, Miller K, Van Veldhuizen P, Morote J, Ye Z, Dansey R, Goessl C. Denosumab and bone metastasis-free survival in men with nonmetastatic castration-resistant prostate cancer: exploratory analyses by baseline prostate-specific antigen doubling time. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3800-6. PMID 24043751 DOI: 10.1200/Jco.2012.44.6716  0.504
2013 Smith MR. Cancer: ADT and acute kidney injury-causal or casual relationship? Nature Reviews. Endocrinology. 9: 568-70. PMID 23959367 DOI: 10.1038/nrendo.2013.167  0.368
2013 Taksler GB, Cutler DM, Giovannucci E, Smith MR, Keating NL. Ultraviolet index and racial differences in prostate cancer incidence and mortality. Cancer. 119: 3195-203. PMID 23744754 DOI: 10.1002/Cncr.28127  0.455
2013 Lee RJ, Saylor PJ, Michaelson MD, Rothenberg SM, Smas ME, Miyamoto DT, Gurski CA, Xie W, Maheswaran S, Haber DA, Goldin JG, Smith MR. A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3088-94. PMID 23553848 DOI: 10.1158/1078-0432.Ccr-13-0319  0.444
2013 Lee RJ, Smith MR. Targeting MET and vascular endothelial growth factor receptor signaling in castration-resistant prostate cancer. Cancer Journal (Sudbury, Mass.). 19: 90-8. PMID 23337762 DOI: 10.1097/Ppo.0B013E318281E280  0.38
2013 Smith MR, Morton RA, Barnette KG, Sieber PR, Malkowicz SB, Rodriguez D, Hancock ML, Steiner MS. Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer. The Journal of Urology. 189: S45-50. PMID 23234631 DOI: 10.1016/j.juro.2012.11.016  0.433
2013 Saylor PJ, Smith MR. Metabolic complications of androgen deprivation therapy for prostate cancer. The Journal of Urology. 189: S34-42; discussion S. PMID 23234628 DOI: 10.1016/j.juro.2012.11.017  0.347
2013 Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, Small EJ, Saad F, et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. The New England Journal of Medicine. 368: 138-48. PMID 23228172 DOI: 10.1056/Nejmoa1209096  0.43
2013 Smith DC, Smith MR, Sweeney C, Elfiky AA, Logothetis C, Corn PG, Vogelzang NJ, Small EJ, Harzstark AL, Gordon MS, Vaishampayan UN, Haas NB, Spira AI, Lara PN, Lin CC, et al. Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 412-9. PMID 23169517 DOI: 10.1200/JCO.2012.45.0494  0.436
2013 Morgans AK, Smith MR, O'Malley AJ, Keating NL. Bone density testing among prostate cancer survivors treated with androgen-deprivation therapy. Cancer. 119: 863-70. PMID 23065626 DOI: 10.1002/cncr.27830  0.332
2013 Keating NL, O'Malley AJ, Freedland SJ, Smith MR. Does comorbidity influence the risk of myocardial infarction or diabetes during androgen-deprivation therapy for prostate cancer? European Urology. 64: 159-66. PMID 22537796 DOI: 10.1016/j.eururo.2012.04.035  0.458
2013 Saad F, Fizazi K, Smith MR, Griffin TW, Londhe A, Rathkopf DE, Molina A, Ryan CJ. Impact of concomitant bone-targeted therapies (BTT) on outcomes in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) without prior chemotherapy (ctx) treated with abiraterone acetate (AA) or prednisone (P). Journal of Clinical Oncology. 31: 5037-5037. DOI: 10.1200/Jco.2013.31.15_Suppl.5037  0.364
2013 Ryan CJ, Londhe A, Molina A, Smith MR, Bono JSD, Mulders P, Rathkopf DE, Saad F, Logothetis C, Fizazi K, Scher HI, Small EJ, Matheny S, Kheoh TS, Griffin TW. Relationship of baseline PSA and degree of PSA decline to radiographic progression-free survival (rPFS) in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302. Journal of Clinical Oncology. 31: 5010-5010. DOI: 10.1200/Jco.2013.31.15_Suppl.5010  0.45
2013 Smith MR, Borre M, Rathenborg P, Werbrouck P, Van Poppel H, Heidenreich A, Iversen P, Baskin-Bey E, Perabo F, Phung D, Tombal B. Efficacy and safety of enzalutamide (ENZA) monotherapy in hormone-naive prostate cancer (HNPC). Journal of Clinical Oncology. 31: 5001-5001. DOI: 10.1200/JCO.2013.31.15_SUPPL.5001  0.432
2013 Van Poppel H, Smith M, Borre M, Rathenborg P, Werbrouck P, Heidenreich A, Iversen P, Baskin-Bey E, Perabo F, Phung D, Tombal B. P061 Efficacy and safety of enzalutamide monotherapy in hormone-naive prostate cancer (HNPC) European Urology Supplements. 12: 152. DOI: 10.1016/S1569-9056(13)62386-6  0.473
2013 Tombal B, Borre M, Rathenborg P, Werbrouck P, Heidenreich A, Iversen P, Baskin-Bey E, Perabo F, Phung D, Smith M. 674 Enzalutamide monotherapy: Results from a phase 2 study in hormone naive prostate cancer patients European Urology Supplements. 12: e674-e675. DOI: 10.1016/S1569-9056(13)61156-2  0.522
2013 Miller K, Smith M, Dearnaley D, Dogliotti L, Egerdie B, Fizazi K, Kueppers F, Montes De Oca L, Morote J, Pavlik I, Sieber P, Tammela T, Van Poppel H, Wirth M, Wong S, et al. 108 Denosumab in men with non-metastatic castration-resistant prostate cancer (CRPC) and PSA doubling time (PSADT) ≤6 months European Urology Supplements. 12: e108-e109. DOI: 10.1016/S1569-9056(13)60600-4  0.531
2013 Patrick D, Smith M, Cleeland C, Fallowfield L, Tombal B, Oudard S, Shore N, Saad F, Marx G, Coleman R, Gómez-Veiga F, Damião R, Zhou Y, Arellano J, Braun A, et al. 99 The impact of bone metastases on pain: Results from a phase III denosumab study in men with nonmetastatic castration-resistant prostate cancer European Urology Supplements. 12: e99-e100. DOI: 10.1016/S1569-9056(13)60591-6  0.458
2013 Van Poppel H, Rathkopf D, Smith M, De Bono J, Logothetis C, Shore N, De Souza P, Fizazi K, Mulders P, Mainwaring P, Hainsworth J, Beer T, North S, Fradet Y, Griffin T, et al. 97 Updated interim analysis (IA): Results of randomized phase 3 study COU-AA-302 of abiraterone acetate (AA) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) without prior chemotherapy European Urology Supplements. 12: e97-e98. DOI: 10.1016/S1569-9056(13)60589-8  0.501
2013 Shore N, Basch E, Ryan CJ, Mulders P, Kheoh T, Fizazi K, Logothetis CJ, Rathkopf D, Smith MR, Mainwaring PN, Hao Y, Griffin T, Li S, Meyers ML, Molina A, et al. 784 THE IMPACT OF ABIRATERONE ACETATE THERAPY ON PATIENT-REPORTED PAIN AND FUNCTIONAL STATUS IN CHEMOTHERAPY-NAÏVE PATIENTS WITH PROGRESSIVE, METASTATIC CASTRATION-RESISTANT PROSTATE CANCER - RESULTS FROM AN UPDATED ANALYSIS Journal of Urology. 189. DOI: 10.1016/J.JURO.2013.02.348  0.453
2012 Smith MR, De Bono JS, Molina A, Logothetis C, De Souza PL, Fizazi K, Mainwaring PN, Piulats Rodriguez JM, Ng S, Carles J, Mulders P, Kheoh TS, Griffin TW, Small EJ, Scher HI, et al. Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate (AA) in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: LBA4518. PMID 28140796 DOI: 10.1200/jco.2012.30.18_suppl.lba4518  0.403
2012 Smith MR, Saad F, Shore ND, Oudard S, Miller K, Tombal B, Sieber P, Fizazi K, Van Veldhuizen PJ, Damião R, Marx GM, Morote J, Feng A, Dansey R, Goessl CD. Effect of denosumab on prolonging bone-metastasis-free survival (BMFS) in men with nonmetastatic castrate-resistant prostate cancer (CRPC) presenting with aggressive PSA kinetics. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 6. PMID 27968276 DOI: 10.1200/jco.2012.30.5_suppl.6  0.424
2012 Saylor PJ, Karoly ED, Smith MR. Changes in plasma metabolomic profiles during the first 3 months of androgen-deprivation therapy for prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 116. PMID 27967973 DOI: 10.1200/jco.2012.30.5_suppl.116  0.397
2012 Efstathiou JA, Paulus R, Smith MR, Jones CU, Leibenhaut MH, Husain SM, Rotman M, Souhami L, Sandler HM, Shipley WU. Cardiovascular mortality following short-term androgen deprivation in clinically localized prostate cancer: An analysis of RTOG 94-08. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 18. PMID 27967830 DOI: 10.1200/jco.2012.30.5_suppl.18  0.504
2012 Miyamoto DT, Lee RJ, Stott SL, Ting DT, Wittner BS, Ulman M, Smas ME, Lord JB, Brannigan BW, Trautwein J, Bander NH, Wu CL, Sequist LV, Smith MR, Ramaswamy S, et al. Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discovery. 2: 995-1003. PMID 23093251 DOI: 10.1158/2159-8290.Cd-12-0222  0.464
2012 Morgans AK, Smith MR. Bone-targeted agents: preventing skeletal complications in prostate cancer. The Urologic Clinics of North America. 39: 533-46. PMID 23084529 DOI: 10.1016/j.ucl.2012.07.009  0.467
2012 Saylor PJ, Mahmood U, Kunawudhi A, Smith MR, Palmer EL, Michaelson MD. Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1670-5. PMID 22984218 DOI: 10.2967/jnumed.112.105007  0.456
2012 Lipton A, Smith MR, Ellis GK, Goessl C. Treatment-induced bone loss and fractures in cancer patients undergoing hormone ablation therapy: efficacy and safety of denosumab. Clinical Medicine Insights. Oncology. 6: 287-303. PMID 22933844 DOI: 10.4137/CMO.S8511  0.346
2012 D'Amico AV, Smith MR. Clinical decisions. Screening for prostate cancer. The New England Journal of Medicine. 367: e11. PMID 22894598 DOI: 10.1056/NEJMclde1209426  0.445
2012 Smith MR, Saad F, Egerdie B, Sieber PR, Tammela TL, Ke C, Leder BZ, Goessl C. Sarcopenia during androgen-deprivation therapy for prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3271-6. PMID 22649143 DOI: 10.1200/Jco.2011.38.8850  0.443
2012 Saylor PJ, Karoly ED, Smith MR. Prospective study of changes in the metabolomic profiles of men during their first three months of androgen deprivation therapy for prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3677-85. PMID 22589396 DOI: 10.1158/1078-0432.CCR-11-3209  0.437
2012 Berruti A, Cook R, Saad F, Buttigliero C, Lipton A, Tampellini M, Lee KA, Coleman RE, Smith MR. Prognostic role of serum parathyroid hormone levels in advanced prostate cancer patients undergoing zoledronic acid administration. The Oncologist. 17: 645-52. PMID 22523198 DOI: 10.1634/Theoncologist.2011-0448  0.503
2012 Hu JC, Williams SB, O'Malley AJ, Smith MR, Nguyen PL, Keating NL. Androgen-deprivation therapy for nonmetastatic prostate cancer is associated with an increased risk of peripheral arterial disease and venous thromboembolism. European Urology. 61: 1119-28. PMID 22336376 DOI: 10.1016/j.eururo.2012.01.045  0.481
2012 Chabner BA, Smith M. Call it cancer. The Oncologist. 17: 149-50. PMID 22302229 DOI: 10.1634/theoncologist.2012-0004  0.329
2012 Saylor PJ, Kozak KR, Smith MR, Ancukiewicz MA, Efstathiou JA, Zietman AL, Jain RK, Duda DG. Changes in Biomarkers of Inflammation and Angiogenesis During Androgen Deprivation Therapy for Prostate Cancer Oncologist. 17: 212-219. PMID 22302227 DOI: 10.1634/Theoncologist.2011-0321  0.349
2012 Morgans AK, Hancock ML, Barnette KG, Steiner MS, Morton RA, Smith MR. Racial differences in bone mineral density and fractures in men receiving androgen deprivation therapy for prostate cancer. The Journal of Urology. 187: 889-93. PMID 22245322 DOI: 10.1016/j.juro.2011.10.136  0.433
2012 Smith MR, Saad F, Coleman R, Shore N, Fizazi K, Tombal B, Miller K, Sieber P, Karsh L, Damião R, Tammela TL, Egerdie B, Van Poppel H, Chin J, Morote J, et al. Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial. Lancet (London, England). 379: 39-46. PMID 22093187 DOI: 10.1016/S0140-6736(11)61226-9  0.456
2012 Michaelson MD, Bellmunt J, Hudes GR, Goel S, Lee RJ, Kantoff PW, Stein CA, Lardelli P, Pardos I, Kahatt C, Nieto A, Cullell-Young M, Lewis NL, Smith MR. Multicenter phase II study of trabectedin in patients with metastatic castration-resistant prostate cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 1234-40. PMID 21930687 DOI: 10.1093/Annonc/Mdr399  0.303
2012 Saad F, Eastham JA, Smith MR. Biochemical markers of bone turnover and clinical outcomes in men with prostate cancer Urologic Oncology-Seminars and Original Investigations. 30: 369-378. PMID 21163673 DOI: 10.1016/J.Urolonc.2010.08.007  0.39
2012 Morgans AK, Smith MR, O'Malley AJ, Keating NL. Osteoporosis screening among prostate cancer survivors treated with androgen deprivation therapy. Journal of Clinical Oncology. 30: 6045-6045. DOI: 10.1200/JCO.2012.30.15_SUPPL.6045  0.389
2012 Fizazi K, Massard C, Smith MR, Rader ME, Brown JE, Milecki P, Shore ND, Oudard S, Karsh LI, Carducci MA, Damião R, Wang H, Goessl CD. Baseline covariates impacting overall survival (OS) in a phase III study of men with bone metastases from castration-resistant prostate cancer. Journal of Clinical Oncology. 30: 4642-4642. DOI: 10.1200/JCO.2012.30.15_SUPPL.4642  0.316
2012 Saad F, Smith MR, Shore ND, Oudard S, Miller K, Tombal B, Sieber P, Fizazi K, Veldhuizen PV, Damiao R, Marx GM, Morote J, Ye Z, Dansey RD, Goessl CD. Effect of denosumab on prolonging bone-metastasis-free survival (BMFS) in men with nonmetastatic castrate-resistant prostate cancer (CRPC) presenting with aggressive PSA kinetics. Journal of Clinical Oncology. 30: 4510-4510. DOI: 10.1200/Jco.2012.30.15_Suppl.4510  0.39
2012 Sonpavde G, Pond G, Armstrong A, Galsky M, Wood B, Wang S, Paolini J, Lechuga M, Smith M, Michaelson M. Association of Progression by Prostate Cancer Working Group (PCWG)-2 Criteria and Survival in Metastatic Castration Resistant Prostate Cancer Annals of Oncology. 23: ix297-ix298. DOI: 10.1016/s0923-7534(20)33529-8  0.552
2012 de Bono J, Smith M, Rathkopf D, Corn P, Mukherji D, Harzstark A, Sartor O, Smith D, Tunariu N, Sweeney C. Cabozantinib (XL184) At 40 Mg in Patients with Metastatic Castration Resistant Prostate Cancer (MCRPC): Results of a Phase 2 Non-Randomized Expansion Cohort (NRE) Annals of Oncology. 23: ix296. DOI: 10.1016/s0923-7534(20)33492-x  0.496
2012 Smith M, Antonarakis E, Ryan C, Berry W, Shore N, Liu G, Alumkal J, Higano C, Chow-Maneval E, Rathkopf D. ARN-509 in Men with High Risk Non-Metastatic Castration-Resistant Prostate Cancer Annals of Oncology. 23: ix303. DOI: 10.1016/s0923-7534(20)33478-5  0.512
2012 Basch E, Ryan C, Kheoh T, Fizazi K, Logothetis C, Rathkopf D, Smith M, Mainwaring P, Hao Y, Griffin T, Li S, Meyers M, Molina A, Cleeland C. The Impact of Abiraterone Acetate (AA) Therapy on Patient-Reported Pain and Functional Status in Chemotherapy-Naive Patients with Progressive, Metastatic Castration-Resistant Prostate Cancer (MCRPC) Annals of Oncology. 23: ix295. DOI: 10.1016/s0923-7534(20)33470-0  0.455
2012 Smith MR, Saad F, Coleman R, Ye Z, Goessl C. Denosumab in castration-resistant prostate cancer – Authors' reply The Lancet. 379. DOI: 10.1016/S0140-6736(12)60765-X  0.366
2012 Smith M, Saad F, Shore N, Oudard S, Miller K, Tombal B, Sieber P, Fizazi K, Veldhuizen PV, Damião R, Marx G, Morote J, Feng A, Dansey R, Goessl C. 681 Denosumab Delays Development Of Multiple Bone Metastases In Men With Castrate-Resistant Prostate Cancer The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.763  0.449
2012 Feldman A, Banyard J, Fergus M, Jedrychowski M, Huttlin E, Gygi S, Smith M, Zettrer B. 2240 DISCOVERY AND ANALYSIS OF PROSTATE CANCER BIOMARKERS IN A STANDARD NON-POST-DRE VOIDED URINE SPECIMEN Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.2416  0.521
2012 Hu J, Williams S, O'Malley A, Smith M, Nguyen P, Keating N. 170 Androgen Deprivation Therapy For Non-Metastatic Prostate Cancer Is Associated With An Increased Risk Of Peripheral Arterial Disease And Venous Thromboembolism The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.221  0.462
2012 Preston M, Carrasquillo R, Coen J, Zietman A, Smith M, Wu C, McDougal WS, Feldman A. 1822 NEED FOR INTERVENTION AND SURVIVAL IN A COHORT OF PATIENTS ON ACTIVE SURVEILLANCE FOR LOW-RISK PROSTATE CANCER Journal of Urology. 187. DOI: 10.1016/J.JURO.2012.02.1888  0.463
2012 Carrasquillo R, Preston M, Coen J, Zietman A, Smith M, Wu C, McDougal WS, Feldman A. 1821 GLEASON UPGRADING AND INCREASED CANCER VOLUME ON REPEAT PROSTATE BIOPSY IN PATIENTS ON ACTIVE SURVEILLANCE Journal of Urology. 187. DOI: 10.1016/J.JURO.2012.02.1887  0.523
2012 Mak K, Yan Y, Smith M, Hanks G, Brereton H, Bauman G, Rosenthal S, Zeitzer K, Sandler H, Efstathiou J. Diabetes and Cardiovascular Mortality in Men With Locally Advanced Prostate Cancer: Updated Analysis From RTOG 92-02 International Journal of Radiation Oncology*Biology*Physics. 84: S94. DOI: 10.1016/j.ijrobp.2012.07.246  0.438
2012 Keating NL, Smith MR, Hu JC. Reply from Authors re: Ramdev Konijeti, Adam S. Kibel. Androgen Deprivation Therapy for Localized and Nonmetastatic Prostate Cancer: Too Much of a Good Thing? Eur Urol 2012;61:1129–30 European Urology. 61: 1131. DOI: 10.1016/J.EURURO.2012.03.044  0.504
2011 Smith DC, Smith MR, Small EJ, Sweeney C, Kurzrock R, Gordon MS, Vogelzang NJ, Scheffold C, Ballinger MD, Hussain M. Phase II study of XL184 in a cohort of patients (pts) with castration-resistant prostate cancer (CRPC) and measurable soft tissue disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 127. PMID 27968542 DOI: 10.1200/Jco.2011.29.7_Suppl.127  0.445
2011 Smith MR, Malkowicz SB, Brawer MK, Hancock ML, Morton RA, Steiner MS. Toremifene decreases vertebral fractures in men younger than 80 years receiving androgen deprivation therapy for prostate cancer. The Journal of Urology. 186: 2239-44. PMID 22014807 DOI: 10.1016/j.juro.2011.07.090  0.351
2011 Morgans AK, Smith MR. RANKL-Targeted Therapies: The Next Frontier in the Treatment of Male Osteoporosis. Journal of Osteoporosis. 2011: 941310. PMID 22013547 DOI: 10.4061/2011/941310  0.437
2011 Smith MR, Klotz L, van der Meulen E, Colli E, Tankó LB. Gonadotropin-releasing hormone blockers and cardiovascular disease risk: analysis of prospective clinical trials of degarelix. The Journal of Urology. 186: 1835-42. PMID 21944083 DOI: 10.1016/j.juro.2011.07.035  0.343
2011 Smith MR, Saad F, Egerdie B, Sieber P, Tammela TLj, Leder BZ, Ke C, Goessl C. Denosumab and changes in bone turnover markers during androgen deprivation therapy for prostate cancer. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2827-33. PMID 21898590 DOI: 10.1002/Jbmr.492  0.313
2011 Saylor PJ, Lee RJ, Smith MR. Emerging therapies to prevent skeletal morbidity in men with prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3705-14. PMID 21860001 DOI: 10.1200/Jco.2010.34.4994  0.488
2011 Saylor PJ, Morton RA, Hancock ML, Barnette KG, Steiner MS, Smith MR. Factors associated with vertebral fractures in men treated with androgen deprivation therapy for prostate cancer. The Journal of Urology. 186: 482-6. PMID 21679977 DOI: 10.1016/j.juro.2011.03.111  0.397
2011 Ryan CJ, Shah S, Efstathiou E, Smith MR, Taplin ME, Bubley GJ, Logothetis CJ, Kheoh T, Kilian C, Haqq CM, Molina A, Small EJ. Phase II study of abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer displaying bone flare discordant with serologic response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4854-61. PMID 21632851 DOI: 10.1158/1078-0432.CCR-11-0815  0.545
2011 Smith MR, Zietman AL, Finkelstein JS, Wu CL. Case records of the Massachusetts General Hospital. Case 16-2011. A 67-year-old man with recurrent prostate cancer. The New England Journal of Medicine. 364: 2044-51. PMID 21612474 DOI: 10.1056/NEJMcpc1011323  0.365
2011 Smith MR. Effective treatment for early-stage prostate cancer - Possible, necessary, or both? New England Journal of Medicine. 364: 1770-1772. PMID 21542749 DOI: 10.1056/NEJMe1100787  0.478
2011 Smith MR, Cook R, Lee KA, Nelson JB. Disease and host characteristics as predictors of time to first bone metastasis and death in men with progressive castration-resistant nonmetastatic prostate cancer. Cancer. 117: 2077-85. PMID 21523719 DOI: 10.1002/Cncr.25762  0.456
2011 Fizazi K, Carducci M, Smith M, Damião R, Brown J, Karsh L, Milecki P, Shore N, Rader M, Wang H, Jiang Q, Tadros S, Dansey R, Goessl C. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet (London, England). 377: 813-22. PMID 21353695 DOI: 10.1016/S0140-6736(10)62344-6  0.519
2011 Saylor PJ, Keating NL, Freedland SJ, Smith MR. Gonadotropin-releasing hormone agonists and the risks of type 2 diabetes and cardiovascular disease in men with prostate cancer. Drugs. 71: 255-61. PMID 21319864 DOI: 10.2165/11588930-000000000-00000  0.395
2011 Hatoum HT, Lin SJ, Guo A, Lipton A, Smith MR. Zoledronic acid therapy impacts risk and frequency of skeletal complications and follow-up duration in prostate cancer patients with bone metastasis. Current Medical Research and Opinion. 27: 55-62. PMID 21083514 DOI: 10.1185/03007995.2010.535511  0.516
2011 Smith MR, Martin TJ. Foreword: skeletal complications of cancer. Bone. 48: 5. PMID 20950719 DOI: 10.1016/j.bone.2010.10.162  0.306
2011 Kim HS, Moreira DM, Smith MR, Presti JC, Aronson WJ, Terris MK, Kane CJ, Amling CL, Freedland SJ. A natural history of weight change in men with prostate cancer on androgen-deprivation therapy (ADT): results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Bju International. 107: 924-8. PMID 20860651 DOI: 10.1111/j.1464-410X.2010.09679.x  0.497
2011 Coen JJ, Feldman AS, Smith MR, Zietman AL. Watchful waiting for localized prostate cancer in the PSA era: what have been the triggers for intervention? Bju International. 107: 1582-6. PMID 20860650 DOI: 10.1111/j.1464-410X.2010.09652.x  0.483
2011 Lee RJ, Saylor PJ, Smith MR. Treatment and prevention of bone complications from prostate cancer. Bone. 48: 88-95. PMID 20621630 DOI: 10.1016/J.Bone.2010.05.038  0.517
2011 Borkowski T, Smith M, Saad F, Coleman R, Shore N, Fizazi K, Tombal B, Miller K, Sieber P, Karsh L, Damiao R, Tammela T, Egerdie B, Van PH, Chin J, et al. C176 Prolonged Bone Metastasis-Free Survival In Men With Castrate-Resistant Prostate Cancer Receiving Denosumab: Results From A Phase 3, Randomised, Double-Blind Trial European Urology Supplements. 10: 656. DOI: 10.1016/S1569-9056(11)61756-9  0.484
2011 Brown J, Cleeland C, Fallowfield L, Patrick D, Fizazi K, Smith M, Maroto J, Michel M, Feng A, Goessl C, Chung K. 1091 PAIN OUTCOMES IN PATIENTS WITH BONE METASTASES FROM CASTRATE-RESISTANT PROSTATE CANCER: RESULTS FROM A PHASE 3 TRIAL OF DENOSUMAB VS. ZOLEDRONIC ACID European Urology Supplements. 10: 336. DOI: 10.1016/S1569-9056(11)61070-1  0.441
2011 Oudard S, Smith M, Karsh L, Egerdie B, Van Veldhuizen P, Gómez-Veiga F, Dearnaley D, Ye Z, Dansey R, Goessl C. 7003 ORAL Denosumab and Bone Metastasis-free Survival in Men With Castrate-resistant Prostate Cancer – Subgroup Analyses From an International, Double-blind, Randomized, Phase 3 Trial European Journal of Cancer. 47: S484-S485. DOI: 10.1016/S0959-8049(11)71954-2  0.485
2011 Patrick D, Cleeland C, Fallowfield L, Smith MR, Trachtenberg J, Chilingirov P, Michel M, Oudard S, Feng A, Goessl C, Chung K. 711 EFFECTS OF DENOSUMAB AND ZOLEDRONIC ACID ON PAIN INTERFERENCE WITH DAILY FUNCTIONING IN PATIENTS WITH CASTRATE-RESISTANT PROSTATE CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1679  0.436
2011 Miller K, Fizazi K, Smith M, Moroto JP, Klotz L, Brown J, Tammela TL, Shore N, Ke C, Chung K, Goessl C. 648 BENEFIT OF DENOSUMAB THERAPY IN PATIENTS WITH BONE METASTASES FROM CASTRATE RESISTANT PROSTATE CANCER: A NUMBER-NEEDED-TO-TREAT (NNT) ANALYSIS Journal of Urology. 185. DOI: 10.1016/j.juro.2011.02.1550  0.512
2011 Brown* J, Carducci M, Fizazi K, Smith M, Damião R, Karsh L, Milecki P, Wang H, Dansey R, Goessl C. Denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer: Results from a phase 3 randomized trial Bone. 48: S16. DOI: 10.1016/J.BONE.2010.10.042  0.482
2010 Lee RJ, Saylor PJ, Smith MR. Contemporary therapeutic approaches targeting bone complications in prostate cancer. Clinical Genitourinary Cancer. 8: 29-36. PMID 21208853 DOI: 10.3816/Cgc.2010.N.005  0.526
2010 Smith MR, Klotz L, Persson BE, Olesen TK, Wilde AA. Cardiovascular safety of degarelix: results from a 12-month, comparative, randomized, open label, parallel group phase III trial in patients with prostate cancer. The Journal of Urology. 184: 2313-9. PMID 20952020 DOI: 10.1016/j.juro.2010.08.012  0.381
2010 Smith MR, Morton RA, Barnette KG, Sieber PR, Malkowicz SB, Rodriguez D, Hancock ML, Steiner MS. Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer. The Journal of Urology. 184: 1316-21. PMID 20723926 DOI: 10.1016/j.juro.2010.06.022  0.433
2010 Faris JE, Smith MR. Metabolic sequelae associated with androgen deprivation therapy for prostate cancer. Current Opinion in Endocrinology, Diabetes, and Obesity. 17: 240-6. PMID 20404727 DOI: 10.1097/MED.0b013e3283391fd1  0.485
2010 Saylor PJ, Kaufman DS, Michaelson MD, Lee RJ, Smith MR. Application of a fracture risk algorithm to men treated with androgen deprivation therapy for prostate cancer. The Journal of Urology. 183: 2200-5. PMID 20399451 DOI: 10.1016/J.Juro.2010.02.022  0.408
2010 Katz MS, Efstathiou JA, D’Amico AV, Kattan MW, Sanda MG, Nguyen PL, Smith MR, Carroll PR, Zietman AL. The 'CaP Calculator': an online decision support tool for clinically localized prostate cancer. Bjui. 105: 1417-1422. PMID 20346051 DOI: 10.1111/J.1464-410X.2010.09290.X  0.456
2010 Efstathiou JA, Shipley WU, Zietman AL, Smith MR. Hormonal therapies: ADT for prostate cancer: true love or heartbreak? Nature Reviews. Clinical Oncology. 7: 130-2. PMID 20190794 DOI: 10.1038/nrclinonc.2010.12  0.526
2010 Ryan CJ, Smith MR, Fong L, Rosenberg JE, Kantoff P, Raynaud F, Martins V, Lee G, Kheoh T, Kim J, Molina A, Small EJ. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1481-8. PMID 20159824 DOI: 10.1200/JCO.2009.24.1281  0.516
2010 Danila DC, Morris MJ, de Bono JS, Ryan CJ, Denmeade SR, Smith MR, Taplin ME, Bubley GJ, Kheoh T, Haqq C, Molina A, Anand A, Koscuiszka M, Larson SM, Schwartz LH, et al. Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1496-501. PMID 20159814 DOI: 10.1200/Jco.2009.25.9259  0.52
2010 Saylor PJ, Smith MR. Adverse effects of androgen deprivation therapy: defining the problem and promoting health among men with prostate cancer. Journal of the National Comprehensive Cancer Network : Jnccn. 8: 211-23. PMID 20141678 DOI: 10.6004/JNCCN.2010.0014  0.482
2010 Levine GN, D'Amico AV, Berger P, Clark PE, Eckel RH, Keating NL, Milani RV, Sagalowsky AI, Smith MR, Zakai N. Androgen-deprivation therapy in prostate cancer and cardiovascular risk: a science advisory from the American Heart Association, American Cancer Society, and American Urological Association: endorsed by the American Society for Radiation Oncology. Ca: a Cancer Journal For Clinicians. 60: 194-201. PMID 20124400 DOI: 10.3322/Caac.20061  0.361
2010 Levine GN, D'Amico AV, Berger P, Clark PE, Eckel RH, Keating NL, Milani RV, Sagalowsky AI, Smith MR, Zakai N. Androgen-deprivation therapy in prostate cancer and cardiovascular risk: a science advisory from the American Heart Association, American Cancer Society, and American Urological Association: endorsed by the American Society for Radiation Oncology. Circulation. 121: 833-40. PMID 20124128 DOI: 10.1161/Circulationaha.109.192695  0.541
2010 Saylor PJ, Keating NL, Smith MR. Prostate cancer survivorship: prevention and treatment of the adverse effects of androgen deprivation therapy. Journal of General Internal Medicine. S389-94. PMID 19838837 DOI: 10.1007/s11606-009-0968-y  0.508
2010 Ryan CJ, Smith MR, Logothetis C, Koepfgen K, Taplin M, Harzstark AL, Kantoff P, Kheoh TS, Molina A, Small EJ. Median time to progression in chemotherapy (chemo)-naive patients with castration-resistant prostate cancer (CRPC) treated with abiraterone acetate and low-dose prednisone (Pred). Journal of Clinical Oncology. 28: 4671-4671. DOI: 10.1200/JCO.2010.28.15_SUPPL.4671  0.494
2010 Smith MR, Cook RJ, Nelson JB. Natural history of castration-resistant nonmetastatic prostate cancer: Secondary analyses of a multicenter randomized controlled trial. Journal of Clinical Oncology. 28: 4653-4653. DOI: 10.1200/Jco.2010.28.15_Suppl.4653  0.521
2010 Lin D, Brawer M, Steiner M, Morton R, Barnette G, Smith M, Yu E. 583 TOREMIFENE IMPROVES PSA PROGRESSION FREE SURVIVAL IN CASTRATE MEN WITH DETECTABLE BASELINE PSA LEVELS Journal of Urology. 183. DOI: 10.1016/J.JURO.2010.02.842  0.312
2010 Klotz L, Smith M, Persson B, Olesen TK, Wilde A. 582 CARDIOVASCULAR SAFETY OF DEGARELIX: RESULTS FROM A 12-MONTH, COMPARATIVE, RANDOMIZED, OPEN-LABEL, PARALLEL-GROUP PHASE III TRIAL IN PROSTATE CANCER PATIENTS Journal of Urology. 183. DOI: 10.1016/J.JURO.2010.02.841  0.444
2010 Smith MR, Saad F, Egerdie B, Sieber P, Tammela TL, Kupic A, Ke C, Leder BZ, Goessl C. 132 SARCOPENIA IN MEN RECEIVING ANDROGEN DEPRIVATION THERAPY (ADT) FOR PROSTATE CANCER: A PROSPECTIVE 3-YEAR STUDY Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.183  0.535
2010 Smith M. Denosumab to Prevent Disease and Treatment-Related Skeletal Complications in Men with Prostate Cancer: Emerging Evidence Bone. 46: S17-S18. DOI: 10.1016/J.BONE.2010.01.029  0.502
2009 Keating NL, O'Malley AJ, Freedland SJ, Smith MR. Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer. Journal of the National Cancer Institute. 102: 39-46. PMID 19996060 DOI: 10.1093/jnci/djp404  0.466
2009 Lipton A, Uzzo R, Amato RJ, Ellis GK, Hakimian B, Roodman GD, Smith MR. The science and practice of bone health in oncology: managing bone loss and metastasis in patients with solid tumors. Journal of the National Comprehensive Cancer Network : Jnccn. 7: S1-29; quiz S30. PMID 19878635 DOI: 10.6004/Jnccn.2009.0080  0.327
2009 Smith MR, Saad F, Egerdie B, Szwedowski M, Tammela TL, Ke C, Leder BZ, Goessl C. Effects of denosumab on bone mineral density in men receiving androgen deprivation therapy for prostate cancer. The Journal of Urology. 182: 2670-5. PMID 19836774 DOI: 10.1016/J.Juro.2009.08.048  0.349
2009 Saylor PJ, Smith MR. Prostate cancer: How can we improve the health of men who receive ADT? Nature Reviews Urology. 6: 529-531. PMID 19806171 DOI: 10.1038/nrurol.2009.195  0.507
2009 Smith MR, Egerdie B, Hernández Toriz N, Feldman R, Tammela TL, Saad F, Heracek J, Szwedowski M, Ke C, Kupic A, Leder BZ, Goessl C. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. The New England Journal of Medicine. 361: 745-55. PMID 19671656 DOI: 10.1056/Nejmoa0809003  0.417
2009 Major PP, Cook RJ, Lipton A, Smith MR, Terpos E, Coleman RE. Natural history of malignant bone disease in breast cancer and the use of cumulative mean functions to measure skeletal morbidity. Bmc Cancer. 9: 272. PMID 19660124 DOI: 10.1186/1471-2407-9-272  0.313
2009 Saylor PJ, Smith MR. Metabolic complications of androgen deprivation therapy for prostate cancer. The Journal of Urology. 181: 1998-2006; discussio. PMID 19286225 DOI: 10.1016/j.juro.2009.01.047  0.347
2009 Efstathiou JA, Bae K, Shipley WU, Hanks GE, Pilepich MV, Sandler HM, Smith MR. Cardiovascular mortality after androgen deprivation therapy for locally advanced prostate cancer: RTOG 85-31. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 92-9. PMID 19047297 DOI: 10.1200/JCO.2007.12.3752  0.478
2009 Isbarn H, Boccon-Gibod L, Carroll PR, Montorsi F, Schulman C, Smith MR, Sternberg CN, Studer UE. Androgen Deprivation Therapy for the Treatment of Prostate Cancer: Consider Both Benefits and Risks European Urology. 55: 62-75. PMID 18945543 DOI: 10.1016/j.eururo.2008.10.008  0.514
2009 Smith M, Egerdie B, Hernández TN, Feldman R, Tammela T, Saad F, Urban M, Szwedowski M, Ke C, Kupic A, Leder B, Goessl C. 846 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF DENOSUMAB IN MEN RECEIVING ANDROGEN DEPRIVATION THERAPY FOR NON-METASTATIC PROSTATE CANCER European Urology Supplements. 8: 332. DOI: 10.1016/S1569-9056(09)60834-4  0.497
2009 Smith M, Egerdie B, Sieber P, Tammela T, Saad F, Ke C, Leder B, Dansey R, Goessl C. 7005 Overall survival in men with and without prevalent vertebral fracture receiving androgen deprivation therapy for nonmetastatic prostate cancer European Journal of Cancer Supplements. 7: 407. DOI: 10.1016/S1359-6349(09)71383-7  0.486
2009 Egerdie B, Smith MR, Tammela TLj, Saad F, Ke C, Goessl C, Dansey R. A RESPONDER ANALYSIS OF THE EFFECTS OF DENOSUMAB ON BONE MINERAL DENSITY IN MEN WITH PROSTATE CANCER RECEIVING ANDROGEN DEPRIVATION THERAPY The Journal of Urology. 181: 611. DOI: 10.1016/S0022-5347(09)61717-1  0.506
2009 Smith MR, Egerdie B, Szwedowski M, Ke C, Leder B, Goessl C. EFFECTS OF TWICE-YEARLY SUBCUTANEOUS DENOSUMAB ON BONE MINERAL DENSITY IN MEN RECEIVING ANDROGEN-DEPRIVATION THERAPY FOR NON-METASTATIC PROSTATE CANCER Journal of Urology. 181: 229-229. DOI: 10.1016/S0022-5347(09)60652-2  0.509
2009 Smith MR, Brown GA, Saad F. New opportunities in the management of prostate cancer–related bone complications Urologic Oncology: Seminars and Original Investigations. 27: S1-S20. DOI: 10.1016/J.UROLONC.2009.08.004  0.406
2009 Smith MR. RANK Ligand-targeted Therapy: A Novel Approach to Prevent Bone Loss and Fractures in Men with Prostate Cancer European Urology, Supplements. 8: 834-838. DOI: 10.1016/j.eursup.2009.08.006  0.365
2008 Ryan C, Smith MR, Rosenberg JE, Lin AM, Taplin M, Kantoff PW, Huey V, Kim J, Small EJ. Impact of prior ketoconazole therapy on response proportion to abiraterone acetate, a 17-alpha hydroxylase C17,20-lyase inhibitor in castration resistant prostate cancer (CRPC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5018. PMID 27948854 DOI: 10.1200/jco.2008.26.15_suppl.5018  0.302
2008 Smith MR, Kyounghwa B, Efstathiou JA, Hanks GE, Pilepich MV, Sandler HM, Shipley WU. Diabetes and mortality in men with locally advanced prostate cancer: analyses of RTOG 92-02. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5013. PMID 27948846 DOI: 10.1200/jco.2008.26.15_suppl.5013  0.452
2008 Brown JE, Hirsh V, Major PP, Lipton A, Cook RJ, Langer CJ, Smith MR, Coleman RE. Survival benefits of zoledronic acid in patients with bone metastases from non-small cell lung cancer and high NTX levels: The role of BALP. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 19003. PMID 27947947 DOI: 10.1200/Jco.2008.26.15_Suppl.19003  0.314
2008 Smith MR. Osteoporosis in men with prostate cancer: Now for the fracture data Journal of Clinical Oncology. 26: 4371-4372. PMID 18802147 DOI: 10.1200/JCO.2008.17.9507  0.461
2008 Smith MR, Bae K, Efstathiou JA, Hanks GE, Pilepich MV, Sandler HM, Shipley WU. Diabetes and mortality in men with locally advanced prostate cancer: RTOG 92-02. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4333-9. PMID 18779620 DOI: 10.1200/JCO.2008.16.5845  0.451
2008 Smith MR. Androgen deprivation therapy and risk for diabetes and cardiovascular disease in prostate cancer survivors Current Urology Reports. 9: 197-202. PMID 18765113 DOI: 10.1007/s11934-008-0035-y  0.474
2008 Smith MR. Osteoclast targeted therapy for prostate cancer: Bisphosphonates and beyond Urologic Oncology: Seminars and Original Investigations. 26: 420-425. PMID 18593621 DOI: 10.1016/j.urolonc.2007.11.004  0.47
2008 Smith MR. Rapid testosterone cycling and chemotherapy for prostate cancer: A way forward or return to the past? Journal of Clinical Oncology. 26: 2932-2933. PMID 18565878 DOI: 10.1200/JCO.2008.16.0788  0.547
2008 Michaelson MD, Cotter SE, Gargollo PC, Zietman AL, Dahl DM, Smith MR. Management of complications of prostate cancer treatment. Ca: a Cancer Journal For Clinicians. 58: 196-213. PMID 18502900 DOI: 10.3322/CA.2008.0002  0.531
2008 Taplin ME, Manola J, Oh WK, Kantoff PW, Bubley GJ, Smith M, Barb D, Mantzoros C, Gelmann EP, Balk SP. A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones. Bju International. 101: 1084-9. PMID 18399827 DOI: 10.1111/J.1464-410X.2008.07509.X  0.511
2008 Smith MR, Malkowicz SB, Chu F, Forrest J, Sieber P, Barnette KG, Rodriquez D, Steiner MS. Toremifene improves lipid profiles in men receiving androgen-deprivation therapy for prostate cancer: interim analysis of a multicenter phase III study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 1824-9. PMID 18398147 DOI: 10.1200/JCO.2007.13.5517  0.431
2008 Smith MR, Lee H, McGovem F, Fallon MA, Goode M, Zietman AL, Finkelstein JS. Metabolic changes during gonadotropin-releasing hormone agonist therapy for prostate cancer: Differences from the classic metabolic syndrome Cancer. 112: 2188-2194. PMID 18348297 DOI: 10.1002/cncr.23440  0.321
2008 Efstathiou JA, Bae K, Shipley WU, Hanks GE, Pilepich MV, Sandler HM, Smith MR. Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02. European Urology. 54: 816-23. PMID 18243498 DOI: 10.1016/j.eururo.2008.01.021  0.475
2008 Keating NL, O'Malley AJ, McNaughton-Collins M, Oh WK, Smith MR. Use of androgen deprivation therapy for metastatic prostate cancer in older men. Bju International. 101: 1077-83. PMID 18190632 DOI: 10.1111/j.1464-410X.2007.07405.x  0.551
2008 Pirl WF, Greer JA, Goode M, Smith MR. Prospective study of depression and fatigue in men with advanced prostate cancer receiving hormone therapy. Psycho-Oncology. 17: 148-53. PMID 17443645 DOI: 10.1002/Pon.1206  0.395
2008 Lee RJ, Smith MR. Osteoclast-targeted therapy for metastatic prostate cancer Therapy. 5: 63-72. DOI: 10.2217/14750708.5.1.63  0.472
2008 Smith MR. Androgen deprivation therapy and risk for diabetes and cardiovascular disease in prostate cancer survivors Current Prostate Reports. 6: 149-154. DOI: 10.1007/s11918-008-0023-1  0.447
2007 Smith MR. Androgen deprivation therapy for prostate cancer: New concepts and concerns Current Opinion in Endocrinology, Diabetes and Obesity. 14: 247-254. PMID 17940447 DOI: 10.1097/MED.0b013e32814db88c  0.45
2007 Smith MR, Cook RJ, Coleman R, Brown J, Lipton A, Major P, Hei YJ, Saad F. Predictors of Skeletal Complications in Men with Hormone-Refractory Metastatic Prostate Cancer Urology. 70: 315-319. PMID 17826496 DOI: 10.1016/J.Urology.2007.03.071  0.48
2007 Saad F, Lipton A, Cook R, Chen Y, Smith M, Coleman R. Pathologic fractures correlate with reduced survival in patients with malignant bone disease. Cancer. 110: 1860-1867. PMID 17763372 DOI: 10.1002/Cncr.22991  0.333
2007 Michaelson MD, Kaufman DS, Lee H, McGovern FJ, Kantoff PW, Fallon MA, Finkelstein JS, Smith MR. Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 1038-42. PMID 17369566 DOI: 10.1200/JCO.2006.07.3361  0.427
2007 Smith MR. Obesity and sex steroids during gonadotropin-releasing hormone agonist treatment for prostate cancer Clinical Cancer Research. 13: 241-245. PMID 17200361 DOI: 10.1158/1078-0432.CCR-06-2086  0.344
2007 Evans W, Smith MR, Morley JE, Barnette KG, Rodriguez D, Steiner MS, Dalton JT. Ostarine increases lean body mass and improves physical performance in healthy elderly subjects: Implications for cancer cachexia patients Journal of Clinical Oncology. 25: 9119-9119. DOI: 10.1200/JCO.2007.25.18_SUPPL.9119  0.358
2007 Lipton A, Cook R, Coleman RE, Major P, Terpos E, Body J, Smith MR, Brown J, Garnero P. Normalization of bone markers and improved survival during zoledronic acid therapy Journal of Clinical Oncology. 25: 9013-9013. DOI: 10.1200/Jco.2007.25.18_Suppl.9013  0.309
2007 Efstathiou JA, Bae K, Shipley WU, Hanks GE, Pilepich MV, Sandler HM, Smith MR. Body mass index and mortality in men treated for locally advanced prostate cancer: An analysis of RTOG 85–31 Journal of Clinical Oncology. 25: 5128-5128. DOI: 10.1200/jco.2007.25.18_suppl.5128  0.495
2007 Smith M, Chu F, Forrest J, Malkowicz SB, Price D, Sieber P, Barnette KG, Rodriguez D, Steiner MS. Effect of toremifene in lowering total cholesterol, LDL, and triglycerides and raising HDL in prostate cancer patients on androgen deprivation therapy Journal of Clinical Oncology. 25: 5124-5124. DOI: 10.1200/JCO.2007.25.18_SUPPL.5124  0.312
2007 Malkowicz SB, Chu F, Forrest J, Smith MR, Price D, Sieber P, Barnette KG, Rodriguez D, Steiner MS. Prevalence of osteoporosis and osteopenia during androgen deprivation (ADT) for prostate cancer: Baseline data from a large randomized controlled trial Journal of Clinical Oncology. 25: 5116-5116. DOI: 10.1200/JCO.2007.25.18_SUPPL.5116  0.429
2007 Smith MR, Chu F, Forrest J, Malkowicz SB, Price D, Sieber P, Barnette K, Rodriguez D, Steiner M. 1015: Phase III Interim Analysis Demonstrates Toremifene Increases Bone Mineral Density in Men Receiving Androgen Deprivation Therapy for Prostate Cancer Journal of Urology. 177: 335-335. DOI: 10.1016/S0022-5347(18)31243-6  0.5
2007 Efstathiou J, Bae K, Shipley W, Hanks G, Pilepich M, Sandler H, Smith M. Cardiovascular Mortality Following Androgen Deprivation Therapy in Men With Locally Advanced Prostate Cancer: An Analysis of RTOG 85-31 International Journal of Radiation Oncology*Biology*Physics. 69: S170-S171. DOI: 10.1016/J.IJROBP.2007.07.309  0.503
2006 Smith MR. Treatment-related osteoporosis in men with prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6315s-6319s. PMID 17062721 DOI: 10.1158/1078-0432.CCR-06-0846  0.373
2006 Keating NL, O'Malley AJ, Smith MR. Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4448-56. PMID 16983113 DOI: 10.1200/JCO.2006.06.2497  0.426
2006 Michaelson MD, Kaufman DS, Kantoff P, Oh WK, Smith MR. Randomized phase II study of atrasentan alone or in combination with zoledronic acid in men with metastatic prostate cancer. Cancer. 107: 530-5. PMID 16804927 DOI: 10.1002/cncr.22043  0.446
2006 Smith MR, Manola J, Kaufman DS, Oh WK, Bubley GJ, Kantoff PW. Celecoxib versus placebo for men with prostate cancer and a rising serum prostate-specific antigen after radical prostatectomy and/or radiation therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 2723-8. PMID 16782912 DOI: 10.1200/JCO.2005.03.7804  0.528
2006 Cook RJ, Coleman R, Brown J, Lipton A, Major P, Hei YJ, Saad F, Smith MR. Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer. Clinical Cancer Research. 12: 3361-3367. PMID 16740758 DOI: 10.1158/1078-0432.Ccr-06-0269  0.496
2006 Smith MR. Markers of bone metabolism in prostate cancer Cancer Treatment Reviews. 32: 23-26. PMID 16680835 DOI: 10.1016/S0305-7372(06)80006-X  0.474
2006 Taneja SS, Smith MR, Dalton JT, Raghow S, Barnette G, Steiner M, Veverka KA. Toremifene--a promising therapy for the prevention of prostate cancer and complications of androgen deprivation therapy. Expert Opinion On Investigational Drugs. 15: 293-305. PMID 16503765 DOI: 10.1517/13543784.15.3.293  0.55
2006 Smith MR. Therapy Insight: osteoporosis during hormone therapy for prostate cancer. Nature Clinical Practice. Urology. 2: 608-15; quiz 628. PMID 16474548 DOI: 10.1038/ncpuro0326  0.444
2006 Smith MR, Lee H, Nathan DM. Insulin sensitivity during combined androgen blockade for prostate cancer. The Journal of Clinical Endocrinology and Metabolism. 91: 1305-8. PMID 16434464 DOI: 10.1210/JC.2005-2507  0.47
2006 Smith MR, Boyce SP, Moyneur E, Duh MS, Raut MK, Brandman J. Risk of clinical fractures after gonadotropin-releasing hormone agonist therapy for prostate cancer. The Journal of Urology. 175: 136-9; discussion 13. PMID 16406890 DOI: 10.1016/S0022-5347(05)00033-9  0.448
2006 Theriault RL, Biermann JS, Brown E, Brufsky A, Demers L, Grewal RK, Guise T, Jackson R, McEnery K, Podoloff D, Ravdin P, Shapiro CL, Smith M, Van Poznak CH. NCCN Task Force Report: Bone Health and Cancer Care Journal of the National Comprehensive Cancer Network. 4: S-1-S-20. DOI: 10.6004/jnccn.2006.2002  0.311
2006 Saad F, Small EJ, Smith MR. Zoledronic Acid Compared With Pamidronate In Patients With Prostate Cancer And Bone Metastases: Effects On Skeletal Complications And Bone Markers European Urology Supplements. 5: 57. DOI: 10.1016/S1569-9056(06)60147-4  0.412
2006 Saad F, Coleman RE, Cook R, Brown JE, Smith M, Hei YJ, Chen YM. Predictors Of Clinical Outcome In Patients With Prostate Cancer And Bone Metastases: Prognostic Significance Of Fractures And Bone Markers European Urology Supplements. 5: 55. DOI: 10.1016/S1569-9056(06)60137-1  0.398
2005 Michaelson MD, Gilligan T, Oh W, Kantoff P, Taplin ME, Izquierdo MA, Flores L, Smith MR. Phase II study of three hour, weekly infusion of trabectedin (ET-743) in men with metastatic, androgen-independent prostate carcinoma (AIPC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4517. PMID 27946533 DOI: 10.1200/jco.2005.23.16_suppl.4517  0.349
2005 Smith MR, Kabbinavar F, Saad F, Hussain A, Hei YJ, Small E, Cook R, Higano C. Natural history of rising serum PSA in men with castrate nonmetastatic prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4514. PMID 27946530 DOI: 10.1200/Jco.2005.23.16_Suppl.4514  0.559
2005 Duh MS, Smith MR, Boyce SP, Moyneur E, Raut MR, Brandman J, Sung JC. Risk factors for clinical fractures among men with non-metastatic prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4560. PMID 27946395 DOI: 10.1200/jco.2005.23.16_suppl.4560  0.483
2005 Michaelson MD, Smith MR. Bisphosphonates for treatment and prevention of bone metastases. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 8219-24. PMID 16278476 DOI: 10.1200/JCO.2005.02.9579  0.344
2005 Smith MR, Lee WC, Brandman J, Wang Q, Botteman M, Pashos CL. Gonadotropin-releasing hormone agonists and fracture risk: a claims-based cohort study of men with nonmetastatic prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7897-903. PMID 16258089 DOI: 10.1200/JCO.2004.00.6908  0.454
2005 Smith MR. Zoledronic acid to prevent skeletal complications in cancer: Corroborating the evidence Cancer Treatment Reviews. 31. PMID 16229955 DOI: 10.1016/j.ctrv.2005.09.004  0.328
2005 Smith MR, Nelson JB. Future therapies in hormone-refractory prostate cancer. Urology. 65: 9-16; discussion 17. PMID 15885273 DOI: 10.1016/j.urology.2005.03.043  0.524
2005 Smith MR, Kabbinavar F, Saad F, Hussain A, Gittelman MC, Bilhartz DL, Wynne C, Murray R, Zinner NR, Schulman C, Linnartz R, Zheng M, Goessl C, Hei YJ, Small EJ, et al. Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 2918-25. PMID 15860850 DOI: 10.1200/Jco.2005.01.529  0.539
2005 Brown JE, Cook RJ, Major P, Lipton A, Saad F, Smith M, Lee KA, Zheng M, Hei YJ, Coleman RE. Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors. Journal of the National Cancer Institute. 97: 59-69. PMID 15632381 DOI: 10.1093/Jnci/Dji002  0.422
2005 Smith MR, Boyce SP, Moyneur E, Duh MS, Raut M, Bradman J, Sung JC, Mallett D. 267: Gonadotropin-Releasing Hormone (GNRH) Agonist Therapy and Fracture Risk in Men with Prostate Cancer Journal of Urology. 173: 74-74. DOI: 10.1016/S0022-5347(18)34532-4  0.423
2004 Smith MR. Osteoporosis and obesity in men receiving hormone therapy for prostate cancer. The Journal of Urology. 172: S52-6; discussion S5. PMID 15535444 DOI: 10.1097/01.JU.0000141820.17959.2F  0.401
2004 Carroll PR, Chan JM, D'Amico AV, Gelmann EP, Iversen P, Klotz L, Nelson JB, Nelson PS, Nelson WG, Oh WK, Rosen N, Rubin MA, Sandler H, Sellers WR, Smith MR, et al. Fourth International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment. The Journal of Urology. 172: S3-5. PMID 15535434 DOI: 10.1097/01.ju.0000142276.19511.ac  0.506
2004 Smith MR, Manola J, Kaufman DS, George D, Oh WK, Mueller E, Slovin S, Spiegelman B, Small E, Kantoff PW. Rosiglitazone versus placebo for men with prostate carcinoma and a rising serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy Cancer. 101: 1569-1574. PMID 15468186 DOI: 10.1002/Cncr.20493  0.412
2004 Smith MR. Osteoclast-targeted therapy for prostate cancer Current Treatment Options in Oncology. 5: 367-375. PMID 15341675 DOI: 10.1007/S11864-004-0027-1  0.543
2004 Smith MR, Fallon MA, Lee H, Finkelstein JS. Raloxifene to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer: A randomized controlled trial Journal of Clinical Endocrinology and Metabolism. 89: 3841-3846. PMID 15292315 DOI: 10.1210/jc.2003-032058  0.338
2004 Oh WK, Kantoff PW, Weinberg V, Jones G, Rini BI, Derynck MK, Bok R, Smith MR, Bubley GJ, Rosen RT, DiPaola RS, Small EJ. Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3705-12. PMID 15289492 DOI: 10.1200/JCO.2004.10.195  0.543
2004 Krupski TL, Smith MR, Lee WC, Pashos CL, Brandman J, Wang Q, Botteman M, Litwin MS. Natural history of bone complications in men with prostate carcinoma initiating androgen deprivation therapy. Cancer. 101: 541-9. PMID 15274067 DOI: 10.1002/cncr.20388  0.455
2004 Smith MR, Goode M, Zietman AL, McGovern FJ, Lee H, Finkelstein JS. Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 2546-53. PMID 15226323 DOI: 10.1200/JCO.2004.01.174  0.379
2004 Michaelson MD, Marujo RM, Smith MR. Contribution of androgen deprivation therapy to elevated osteoclast activity in men with metastatic prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2705-8. PMID 15102674 DOI: 10.1158/1078-0432.CCR-03-0735  0.556
2004 Smith MR. Changes in fat and lean body mass during androgen-deprivation therapy for prostate cancer Urology. 63: 742-745. PMID 15072892 DOI: 10.1016/j.urology.2003.10.063  0.416
2004 Diamond TH, Higano CS, Smith MR, Guise TA, Singer FR. Osteoporosis in men with prostate carcinoma receiving androgen-deprivation therapy: recommendations for diagnosis and therapies. Cancer. 100: 892-9. PMID 14983482 DOI: 10.1002/cncr.20056  0.434
2004 Kazanis M, Smith MR. Treatment-Related Osteoporosis in Men With Prostate Cancer Clinical Reviews in Bone and Mineral Metabolism. 2: 115-122. DOI: 10.1385/BMM:2:2:115  0.534
2004 Oh WK, Hagmann E, Manola J, George DJ, Gilligan TD, Smith MR, Kaufman DS, Kantoff PW. A phase I study of estramustine, weekly docetaxel and carboplatin (EDC) chemotherapy in patients with hormone refractory prostate cancer (HRPC) Journal of Clinical Oncology. 22: 4656-4656. DOI: 10.1200/jco.2004.22.90140.4656  0.525
2004 Smith MR, Lee WC, Krupsi T, Brandman J, Wang Q, Botteman M, Pashos C, Litwin M. Association between androgen deprivation therapy and fracture risk: A population-based cohort study in men with non-metastatic prostate cancer Journal of Clinical Oncology. 22: 4507-4507. DOI: 10.1200/JCO.2004.22.90140.4507  0.468
2004 Krupski TL, Smith MR, Lee WC, Pashas CL, Brandman J, Wang Q, Botteman MF, Litwin MS. 438: Fracture Risk in Men with Prostate Cancer on Androgen Deprivation Therapy Journal of Urology. 171: 116-116. DOI: 10.1016/S0022-5347(18)37700-0  0.481
2003 Smith MR. Changes in body composition during hormonal therapy for prostate cancer Clinical Prostate Cancer. 2: 18-21. PMID 15046678 DOI: 10.3816/CGC.2003.N.008  0.356
2003 Smith MR, Kantoff PW, Carroll PR, Benaron DA, Sellers WR, Higano CS. Bisphosphonates to prevent skeletal complications in men with metastatic prostate cancer Journal of Urology. 170: S55-S58. PMID 14610411 DOI: 10.1097/01.ju.0000095102.34708.bc  0.551
2003 Carroll PR, Benaron DA, Blackledge G, Coakley FV, D'Amico AV, Higano CS, Iversen P, Kattan M, Nanus DM, Nelson JB, Oh WK, Roach M, Sellers WR, Smith MR, McMann MC, et al. Third international conference on innovations and challenges in prostate cancer: prevention, detection and treatment. The Journal of Urology. 170: S3-5. PMID 14610403 DOI: 10.1097/01.Ju.0000095101.18470.A0  0.507
2003 Small EJ, Smith MR, Seaman JJ, Petrone S, Kowalski MO. Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 4277-84. PMID 14581438 DOI: 10.1200/JCO.2003.05.147  0.486
2003 Oh WK, Manola J, Bittmann L, Brufsky A, Kaplan ID, Smith MR, Kaufman DS, Kantoff PW. Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up. Urology. 62: 99-104. PMID 12837431 DOI: 10.1016/S0090-4295(03)00145-6  0.557
2003 Smith MR. Management of treatment-related osteoporosis in men with prostate cancer Cancer Treatment Reviews. 29: 211-218. PMID 12787715 DOI: 10.1016/S0305-7372(03)00076-8  0.373
2003 Smith MR, Eastham J, Gleason DM, Shasha D, Tchekmedyian S, Zinner N. Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. The Journal of Urology. 169: 2008-12. PMID 12771706 DOI: 10.1097/01.ju.0000063820.94994.95  0.487
2003 Michaelson MD, Smith MR. The role of bisphosphonates in the management of metastatic prostate cancer. Current Oncology Reports. 5: 245-9. PMID 12667423 DOI: 10.1007/S11912-003-0117-4  0.575
2003 Smith MR. Bisphosphonates to prevent osteoporosis in men receiving androgen deprivation therapy for prostate cancer Drugs and Aging. 20: 175-183. PMID 12578398 DOI: 10.2165/00002512-200320030-00002  0.405
2003 Smith MR, Fallon MA, Goode MJ. Cross-sectional study of bone turnover during bicalutamide monotherapy for prostate cancer Urology. 61: 127-131. PMID 12559282 DOI: 10.1016/S0090-4295(02)02006-X  0.346
2003 Smith MR. Diagnosis and management of treatment-related osteoporosis in men with prostate carcinoma Cancer. 97: 789-795. PMID 12548577 DOI: 10.1002/cncr.11149  0.379
2003 Pirl WF, Siegel GI, Goode MJ, Smith MR. Depression in men receiving androgen deprivation therapy for prostate cancer: a pilot study. Psycho-Oncology. 11: 518-23. PMID 12476433 DOI: 10.1002/PON.592  0.494
2002 Smith MR. Osteoporosis and other adverse body composition changes during androgen deprivation therapy for prostate cancer Cancer and Metastasis Reviews. 21: 159-166. PMID 12465755 DOI: 10.1023/A:1020840311573  0.39
2002 Smith MR, Kaufman D, George D, Oh WK, Kazanis M, Manola J, Kantoff PW. Selective aromatase inhibition for patients with androgen-independent prostate carcinoma. Cancer. 95: 1864-8. PMID 12404279 DOI: 10.1002/cncr.10844  0.405
2002 Smith MR. Osteoporosis during androgen deprivation therapy for prostate cancer Urology. 60: 79-86. PMID 12231056 DOI: 10.1016/S0090-4295(02)01579-0  0.417
2002 Carroll PR, Kantoff PW, Balk SP, Brown MA, D'amico AV, George DJ, Grossfeld GD, Johnson CS, Kelly WK, Klotz L, Lee WR, Lubeck DP, Mcleod DG, Oh WK, Pollack A, ... Smith MR, et al. Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer. Urology. 60: 1-6. PMID 12231036  0.531
2002 Smith MR, Kantoff PW. Peroxisome proliferator-activated receptor gamma (PPargamma) as a novel target for prostate cancer. Investigational New Drugs. 20: 195-200. PMID 12099579 DOI: 10.1023/A:1015670126203  0.416
2002 Smith MR, Fuchs V, Anderson EJ, Fallon MA, Manola J. Measurement of body fat by dual-energy x-ray absorptiometry and bioimpedance analysis in men with prostate cancer Nutrition. 18: 574-577. PMID 12093432 DOI: 10.1016/S0899-9007(02)00821-3  0.313
2002 Smith MR, Finkelstein JS, McGovern FJ, Zietman AL, Fallon MA, Schoenfeld DA, Kantoff PW. Changes in body composition during androgen deprivation therapy for prostate cancer Journal of Clinical Endocrinology and Metabolism. 87: 599-603. PMID 11836291 DOI: 10.1210/Jcem.87.2.8299  0.325
1999 Smith MR, Kantoff PW, Oh W, Elson G, Manola J, McMullin M, Jacobsen J, Brufsky A, Kaufman D. Phase II Trial of the Antiestrogen Toremifene for Androgen-Independent Prostate Cancer The Prostate Journal. 1: 185-189. DOI: 10.1046/J.1525-1411.1999.14003.X  0.497
1999 Smith MR. Androgen Deprivation and Osteoporosis The Prostate Journal. 1: 161-165. DOI: 10.1046/J.1525-1411.1999.14002.X  0.381
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