Danhui Zhang, Ph.D. - Related publications

2008 Biomedical Sciences Iowa State University, Ames, IA, United States 
Neuroscience, Toxicology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Helton LG, Soliman A, von Zweydorf F, Kentros M, Manschwetus JT, Hall S, Gilsbach B, Ho FY, Athanasopoulos PS, Singh RK, LeClair TJ, Versées W, Raimondi F, Herberg FW, Gloeckner CJ, et al. Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides. Acs Chemical Biology. PMID 34496561 DOI: 10.1021/acschembio.1c00487   
2021 Drysch M, Schmidt SV, Becerikli M, Reinkemeier F, Dittfeld S, Wagner JM, Dadras M, Sogorski A, von Glinski M, Lehnhardt M, Behr B, Wallner C. Myostatin Deficiency Protects C2C12 Cells from Oxidative Stress by Inhibiting Intrinsic Activation of Apoptosis. Cells. 10. PMID 34359850 DOI: 10.3390/cells10071680   
2021 Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, et al. TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nature Communications. 12: 5337. PMID 34504101 DOI: 10.1038/s41467-021-25622-3   
2021 Hou XO, Tu HY, Qian HC, Li Q, Yang YP, Xu GQ, Wang F, Liu CF, Wang YL, Hu LF. AMPK S-sulfuration contributes to HS donors-induced AMPK phosphorylation and autophagy activation in dopaminergic cells. Neurochemistry International. 105187. PMID 34534609 DOI: 10.1016/j.neuint.2021.105187   
2021 Madhi I, Kim JH, Shin JE, Kim Y. Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia. Molecular Medicine Reports. 24. PMID 34368872 DOI: 10.3892/mmr.2021.12337   
2021 Albanese F, Mercatelli D, Finetti L, Lamonaca G, Pizzi S, Shimshek DR, Bernacchia G, Morari M. Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Neurobiology of Disease. 159: 105487. PMID 34419621 DOI: 10.1016/j.nbd.2021.105487   
2021 Ali S, Khan MR, Iqbal J, Batool R, Naz I, Yaseen T, Abbasi BA, Nasir JA, El-Serehy HA. Chemical composition and pharmacological bio-efficacy of (Decne) Rehder for anticancer activity. Saudi Journal of Biological Sciences. 28: 4969-4986. PMID 34466072 DOI: 10.1016/j.sjbs.2021.07.072   
2021 Xu Y, Ji Y, Li X, Ding J, Chen L, Huang Y, Wei W. URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells. International Journal of Biological Sciences. 17: 3091-3103. PMID 34421352 DOI: 10.7150/ijbs.55689   
2021 Weeks AM. Kinases leave their mark on caspase substrates. The Biochemical Journal. 478: 3179-3184. PMID 34492095 DOI: 10.1042/BCJ20210399   
2021 Jadaun KS, Sharma A, Siddiqui EM, Mehan S. Targeting abnormal PI3K/AKT/mTOR signaling in intracerebral hemorrhage: A systematic review on potential drug targets and influences of signaling modulators on other neurological disorders. Current Reviews in Clinical and Experimental Pharmacology. PMID 34455956 DOI: 10.2174/1574884716666210726110021   
2021 Ogata J, Hirao K, Nishioka K, Hayashida A, Li Y, Yoshino H, Shimizu S, Hattori N, Imai Y. A Novel LRRK2 Variant p.G2294R in the WD40 Domain Identified in Familial Parkinson's Disease Affects LRRK2 Protein Levels. International Journal of Molecular Sciences. 22. PMID 33918221 DOI: 10.3390/ijms22073708   
2021 Chaisit S, Jianmongkol S. Apoptosis Inducing Activity of Rhinacanthin-C in Doxorubicin-Resistant Breast Cancer MCF-7 Cells. Biological & Pharmaceutical Bulletin. 44: 1239-1246. PMID 34471052 DOI: 10.1248/bpb.b21-00015   
2021 Singh F, Prescott AR, Rosewell P, Ball G, Reith AD, Ganley IG. Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice. Elife. 10. PMID 34340748 DOI: 10.7554/eLife.67604   
2021 Ahmadu AA, Delehouzé C, Haruna A, Mustapha L, Lawal BA, Udobre A, Baratte B, Triscornia C, Autret A, Robert T, Bulinski JC, Rousselot M, Simoes Eugénio M, Dimanche-Boitrel MT, Petzer JP, et al. Betulin, a Newly Characterized Compound in Bark, Is a Multi-Target Protein Kinase Inhibitor. Molecules (Basel, Switzerland). 26. PMID 34361750 DOI: 10.3390/molecules26154599   
2021 Chen J, Ye C, Wan C, Li G, Peng L, Peng Y, Fang R. The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases. International Journal of Molecular Sciences. 22. PMID 34502556 DOI: 10.3390/ijms22179640   
2021 Herbst S, Lewis PA. From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's disease. The Biochemical Journal. 478: 2945-2951. PMID 34328508 DOI: 10.1042/BCJ20210383   
2021 Shu ST, Li WF, Smithgall TE. Visualization of Host Cell Kinase Activation by Viral Proteins Using GFP Fluorescence Complementation and Immunofluorescence Microscopy. Bio-Protocol. 11: e4068. PMID 34327265 DOI: 10.21769/BioProtoc.4068   
2021 Preynat-Seauve O, Nguyen EB, Westermaier Y, Héritier M, Tardy S, Cambet Y, Feyeux M, Caillon A, Scapozza L, Krause KH. Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation. Frontiers in Pharmacology. 12: 664608. PMID 34421588 DOI: 10.3389/fphar.2021.664608   
2021 Lim SR, Kim DW, Sung J, Kim TH, Choi CH, Lee SJ. Astaxanthin Inhibits Autophagic Cell Death Induced by Bisphenol A in Human Dermal Fibroblasts. Antioxidants (Basel, Switzerland). 10. PMID 34439521 DOI: 10.3390/antiox10081273   
2021 Kang HM, Won KJ, Kim DY, Lee SY, Kim MJ, Won YR, Kim B, Lee HM. Chemical composition of Miscanthus sinensis var. purpurascens flower absolute and its beneficial effects on skin wound healing and melanogenesis-related cell activities. Chemistry & Biodiversity. PMID 34405949 DOI: 10.1002/cbdv.202100383   
2021 Lee BJ, Mallya S, Dinglasan N, Fung A, Nguyen T, Herzog LO, Thao J, Lorenzana EG, Wildes D, Singh M, Smith JAM, Fruman DA. Efficacy of a Novel Bi-Steric mTORC1 Inhibitor in Models of B-Cell Acute Lymphoblastic Leukemia. Frontiers in Oncology. 11: 673213. PMID 34408976 DOI: 10.3389/fonc.2021.673213   
2021 Liu Q, Bautista-Gomez J, Higgins DA, Yu J, Xiong Y. Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration. Science Signaling. 14. PMID 34315807 DOI: 10.1126/scisignal.abg3555   
2021 Liu Q, Bautista-Gomez J, Higgins DA, Yu J, Xiong Y. Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration. Science Signaling. 14. PMID 34315807 DOI: 10.1126/scisignal.abg3555   
2021 Tan S, Gong X, Liu H, Yao X. Virtual Screening and Biological Activity Evaluation of New Potent Inhibitors Targeting LRRK2 Kinase Domain. Acs Chemical Neuroscience. PMID 34387082 DOI: 10.1021/acschemneuro.1c00399   
2021 Zheng CR, Singh A, Libby A, Silver PA, Libby EA. Modular and Single-Cell Sensors of Bacterial Ser/Thr Kinase Activity. Acs Synthetic Biology. PMID 34463482 DOI: 10.1021/acssynbio.1c00250   
2021 Qiu S, Liu Y, Li Q. A mechanism for localized dynamics-driven activation in Bruton's tyrosine kinase. Royal Society Open Science. 8: 210066. PMID 34457331 DOI: 10.1098/rsos.210066   
2021 Zummo FP, Krishnanda SI, Georgiou M, O'Harte FP, Parthsarathy V, Cullen KS, Honkanen-Scott M, Shaw JA, Lovat PE, Arden C. Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca-PPP3/calcineurin-TFEB axis. Autophagy. 1-17. PMID 34338148 DOI: 10.1080/15548627.2021.1956123   
2021 Kim TI, Kim YJ, Kim K. Extract of Seaweed Inhibits Integrin αIIbβ3-Induced Outside-in Signaling and Arterial Thrombosis. Frontiers in Pharmacology. 12: 685948. PMID 34276375 DOI: 10.3389/fphar.2021.685948   
2021 Minakhina S, De Oliveira V, Kim SY, Zheng H, Wondisford FE. Thyroid hormone receptor phosphorylation regulates acute fasting-induced suppression of the hypothalamic-pituitary-thyroid axis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34544870 DOI: 10.1073/pnas.2107943118   
2021 Kondo Y, Paul JW, Subramaniam S, Kuriyan J. New insights into Raf regulation from structural analyses. Current Opinion in Structural Biology. 71: 223-231. PMID 34454301 DOI: 10.1016/j.sbi.2021.07.005   
2021 Arribas-Blázquez M, Piniella D, Olivos-Oré LA, Bartolomé-Martín D, Leite C, Giménez C, Artalejo AR, Zafra F. Regulation of the voltage-dependent sodium channel Na1.1 by AKT1. Neuropharmacology. 197: 108745. PMID 34375627 DOI: 10.1016/j.neuropharm.2021.108745   
2021 McLeod IX, Saxena R, Carico Z, He YW. Class I PI3K Provide Lipid Substrate in T Cell Autophagy Through Linked Activity of Inositol Phosphatases. Frontiers in Cell and Developmental Biology. 9: 709398. PMID 34458267 DOI: 10.3389/fcell.2021.709398   
2021 Bie N, Feng X, Li C, Meng M, Wang C. The Protective Effect of Docosahexaenoic Acid on PC12 Cells in Oxidative Stress Induced by HO through the TrkB-Erk1/2-CREB Pathway. Acs Chemical Neuroscience. PMID 34428890 DOI: 10.1021/acschemneuro.1c00421   
2021 Ma J, Ren Y, Zhang JN, Lin L, Zhang YL. [Analysis on targets of regulating Qi and activating blood based on activity spectrum of targets]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 3970-3979. PMID 34472274 DOI: 10.19540/j.cnki.cjcmm.20210303.401   
2021 Zheng F, Meng T, Jiang D, Sun J, Yao H, Zhu JJ, Min Q. Nano-mediator-effector cascade systems for amplified protein kinase activity imaging and phosphorylation-induced drug release in vivo. Angewandte Chemie (International Ed. in English). PMID 34322988 DOI: 10.1002/anie.202109108   
2021 Zheng F, Meng T, Jiang D, Sun J, Yao H, Zhu JJ, Min Q. Nano-mediator-effector cascade systems for amplified protein kinase activity imaging and phosphorylation-induced drug release in vivo. Angewandte Chemie (International Ed. in English). PMID 34322988 DOI: 10.1002/anie.202109108   
2021 El-Sayed N, Mostafa YM, AboGresha NM, Ahmed AAM, Mahmoud IZ, El-Sayed NM. Dapagliflozin attenuates diabetic cardiomyopathy through erythropoietin up-regulation of AKT/JAK/MAPK pathways in streptozotocin-induced diabetic rats. Chemico-Biological Interactions. 347: 109617. PMID 34391751 DOI: 10.1016/j.cbi.2021.109617   
2021 Takei GL, Tourzani DA, Paudel B, Visconti PE. Activation of cAMP-dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation. Molecular Reproduction and Development. PMID 34318548 DOI: 10.1002/mrd.23524   
2021 Che J, Dai X, Gao J, Sheng H, Zhan W, Lu Y, Li D, Gao Z, Jin Z, Chen B, Luo P, Yang B, Hu Y, He Q, Weng Q, et al. Discovery of -((3,4)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity. Journal of Medicinal Chemistry. PMID 34375113 DOI: 10.1021/acs.jmedchem.1c00815   
2021 Dong JR, Chang WW, Chen SM. Nerolidol inhibits proliferation of leiomyoma cells via reactive oxygen species-induced DNA damage and downregulation of the ATM/Akt pathway. Phytochemistry. 191: 112901. PMID 34388663 DOI: 10.1016/j.phytochem.2021.112901   
2021 Yu Z, Jiang N, Su W, Zhuo Y. Necroptosis: A Novel Pathway in Neuroinflammation. Frontiers in Pharmacology. 12: 701564. PMID 34322024 DOI: 10.3389/fphar.2021.701564   
2021 Drewry DH, Annor-Gyamfi JK, Wells CI, Pickett JE, Dederer V, Preuss F, Mathea S, Axtman AD. Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration. Journal of Medicinal Chemistry. PMID 34333981 DOI: 10.1021/acs.jmedchem.1c00440   
2021 Bolz SN, Salentin S, Jennings G, Haupt VJ, Sterneckert J, Schroeder M. Structural binding site comparisons reveal Crizotinib as a novel LRRK2 inhibitor. Computational and Structural Biotechnology Journal. 19: 3674-3681. PMID 34285770 DOI: 10.1016/j.csbj.2021.06.013   
2021 Yun Y, Hong VS, Jeong S, Choo H, Kim S, Lee J. 2-Thioxothiazolidin-4-one Analogs as Pan-PIM Kinase Inhibitors. Chemical & Pharmaceutical Bulletin. 69: 854-861. PMID 34470949 DOI: 10.1248/cpb.c21-00264   
2021 Lee JI, Seo JH, Ko ES, Cho SM, Kang JR, Jeong JH, Jeong YJ, Kim CY, Cha JD, Kim WS, Ryu YB. Inhibition of melanogenesis by callus pellet extract in melanoma cells and patients with skin pigmentation. International Journal of Medical Sciences. 18: 3299-3308. PMID 34400899 DOI: 10.7150/ijms.62530   
2021 Horvath C, Young M, Jarabicova I, Kindernay L, Ferenczyova K, Ravingerova T, Lewis M, Suleiman MS, Adameova A. Inhibition of Cardiac RIP3 Mitigates Early Reperfusion Injury and Calcium-Induced Mitochondrial Swelling without Altering Necroptotic Signalling. International Journal of Molecular Sciences. 22. PMID 34360749 DOI: 10.3390/ijms22157983   
2021 Mahajan K, Verma H, Choudhary S, Raju B, Silakari O. Identification of kinase inhibitors that rule out the CYP27B1-mediated activation of vitamin D: an integrated machine learning and structure-based drug designing approach. Molecular Diversity. PMID 34272637 DOI: 10.1007/s11030-021-10270-y   
2021 Wei LY, Lin W, Leo BF, Kiew LV, Chang CC, Yuan CJ. Development of the Sensing Platform for Protein Tyrosine Kinase Activity. Biosensors. 11. PMID 34356711 DOI: 10.3390/bios11070240   
2021 Ye Y, Cai Y, Xia E, Shi K, Jin Z, Chen H, Xia F, Xia Y, Papadimos TJ, Xu X, Liu L, Wang Q. Apelin-13 Reverses Bupivacaine-Induced Cardiotoxicity via the Adenosine Monophosphate-Activated Protein Kinase Pathway. Anesthesia and Analgesia. 133: 1048-1059. PMID 34524989 DOI: 10.1213/ANE.0000000000005692   
2021 Karia P, Yoshioka K, Moeder W. Multiple phosphorylation events of the mitochondrial membrane protein TTM1 regulate cell death during senescence. The Plant Journal : For Cell and Molecular Biology. PMID 34409658 DOI: 10.1111/tpj.15470