Year |
Citation |
Score |
2023 |
Johnson AM, Jose S, Palakkott AR, Khan FB, Jayabalan N, Kizhakkayil J, AlNaqbi SAA, Scott MG, Ayoub MA, Gordon R, Saminathan H. Pharmacological Inhibition of PTEN Rescues Dopaminergic Neurons by Attenuating Apoptotic and Neuroinflammatory Signaling Events. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 37589761 DOI: 10.1007/s11481-023-10077-8 |
0.665 |
|
2021 |
Johnson AM, Ou ZA, Gordon R, Saminathan H. Environmental neurotoxicants and inflammasome activation in Parkinson's disease - a focus on the gut-brain axis. The International Journal of Biochemistry & Cell Biology. 106113. PMID 34737076 DOI: 10.1016/j.biocel.2021.106113 |
0.545 |
|
2021 |
Saminathan H, Ghosh A, Zhang D, Song C, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease. Frontiers in Pharmacology. 12: 631375. PMID 33995031 DOI: 10.3389/fphar.2021.631375 |
0.744 |
|
2020 |
Saminathan H, Charli A, Luo J, Panicker N, Gordon R, Hostetter JM, Jin H, Anantharam V, Kanthasamy AG, Kanthasamy A. Fyn kinase mediates pro-inflammatory response in a mouse model of endotoxemia: Relevance to translational research. European Journal of Pharmacology. 173259. PMID 32565338 DOI: 10.1016/J.Ejphar.2020.173259 |
0.741 |
|
2019 |
Panicker N, Sarkar S, Harischandra DS, Neal M, Kam TI, Jin H, Saminathan H, Langley M, Charli A, Samidurai M, Rokad D, Ghaisas S, Pletnikova O, Dawson VL, Dawson TM, et al. Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia. The Journal of Experimental Medicine. PMID 31036561 DOI: 10.1084/Jem.20182191 |
0.688 |
|
2015 |
Panicker N, Saminathan H, Jin H, Neal M, Harischandra DS, Gordon R, Kanthasamy K, Lawana V, Sarkar S, Luo J, Anantharam V, Kanthasamy AG, Kanthasamy A. Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10058-77. PMID 26157004 DOI: 10.1523/Jneurosci.0302-15.2015 |
0.69 |
|
2013 |
Ghosh A, Saminathan H, Kanthasamy A, Anantharam V, Jin H, Sondarva G, Harischandra DS, Qian Z, Rana A, Kanthasamy AG. The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. The Journal of Biological Chemistry. 288: 21955-71. PMID 23754278 DOI: 10.1074/Jbc.M112.444224 |
0.74 |
|
2011 |
Saminathan H, Asaithambi A, Anantharam V, Kanthasamy AG, Kanthasamy A. Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model. Neurotoxicology. 32: 567-77. PMID 21801747 DOI: 10.1016/J.Neuro.2011.06.009 |
0.73 |
|
2011 |
Asaithambi A, Kanthasamy A, Saminathan H, Anantharam V, Kanthasamy AG. Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration. Molecular Neurodegeneration. 6: 43. PMID 21696630 DOI: 10.1186/1750-1326-6-43 |
0.679 |
|
Low-probability matches (unlikely to be authored by this person) |
2022 |
Luo G, Chen L, Kostich WA, Hamman B, Allen J, Easton A, Bourin C, Gulianello M, Lippy J, Nara S, Pattipati SN, Dandapani K, Dokania M, Vattikundala P, Sharma V, ... ... Saminathan H, et al. Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain. Journal of Medicinal Chemistry. PMID 35261239 DOI: 10.1021/acs.jmedchem.1c02132 |
0.179 |
|
2022 |
Luo G, Chen L, Kostich WA, Hamman B, Allen J, Easton A, Bourin C, Gulianello M, Lippy J, Nara S, Maishal TK, Thiyagarajan K, Jalagam P, Pattipati SN, Dandapani K, ... ... Saminathan H, et al. Discovery of ()-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain. Journal of Medicinal Chemistry. PMID 35257579 DOI: 10.1021/acs.jmedchem.1c02131 |
0.147 |
|
2021 |
Johnson AM, Barigye R, Saminathan H. Perspectives on the use and risk of adverse events associated with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases. Human Vaccines & Immunotherapeutics. 1-17. PMID 33974497 DOI: 10.1080/21645515.2021.1908060 |
0.078 |
|
Hide low-probability matches. |