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Daniel J. Murphy, Ph.D. - Publications

Affiliations: 
2000 University of Virginia, Charlottesville, VA 
Area:
Microbiology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Whyte D, Skalka G, Walsh P, Wilczynska A, Paul NR, Mitchell C, Nixon C, Clarke W, Bushell M, Morton JP, Murphy DJ, Muthalagu N. NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology. PMID 36975767 DOI: 10.1002/1878-0261.13425  0.309
2020 Rodrigues FS, Miranda VS, Carneiro-Lobo TC, Scalabrini LC, Kruspig B, Levantini E, Murphy DJ, Bassères DS. IKKβ Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells. International Journal of Molecular Sciences. 21. PMID 32823550 DOI: 10.3390/Ijms21165806  0.37
2020 Muthalagu N, Monteverde T, Raffo-Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, Laing S, Kruspig B, Upstill-Goddard R, Shaw R, Neidler S, Rink C, Karim SA, Gyuraszova K, Nixon C, ... ... Murphy DJ, et al. Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma. Cancer Discovery. PMID 32200350 DOI: 10.1158/2159-8290.Cd-19-0620  0.388
2020 Yun S, Vincelette ND, Fernandez M, Yu X, Yang C, Hitosugi T, Cheng C, Freischel A, Zhang L, Watson G, Li W, Hou H, Schaub FX, Vedder A, Cen L, ... ... Murphy D, et al. Tfeb Links MYC Signaling to Epigenetic Control of Acute Myeloid Leukemia Cell Death and Differentiation Blood. 136: 12-13. DOI: 10.1182/BLOOD-2020-137209  0.309
2019 Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, ... ... Murphy DJ, et al. Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Reports. 29: 1287-1298.e6. PMID 31665640 DOI: 10.1016/J.Celrep.2019.09.056  0.355
2019 Neidler S, Kruspig B, Hewit K, Monteverde T, Gyuraszova K, Braun A, Clark W, James D, Hedley A, Nieswandt B, Shanks E, Dick C, Murphy DJ. Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma. Cancers. 11. PMID 31032816 DOI: 10.3390/Cancers11050600  0.375
2018 Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, Clark W, Hedley A, Laing S, Coffelt SB, Le Quesne J, Dick C, Vousden K, Martins CP, Murphy DJ. The ERBB network facilitates KRAS-driven lung tumorigenesis. Science Translational Medicine. 10. PMID 29925636 DOI: 10.1016/S0959-8049(16)61337-0  0.332
2018 Port JLF, Muthalagu N, Raja M, Ceteci F, Monteverde T, Kruspig B, Hedley A, Kalna G, Lilla S, Neilson L, Brucoli M, Gyuraszova K, Tait-Mulder J, Mezna M, Svambaryte S, ... ... Murphy DJ, et al. Colorectal tumors require NUAK1 for protection from oxidative stress. Cancer Discovery. PMID 29500295 DOI: 10.1158/2159-8290.Cd-17-0533  0.334
2017 Walton JB, Farquharson M, Mason S, Port J, Kruspig B, Dowson S, Stevenson D, Murphy D, Matzuk M, Kim J, Coffelt S, Blyth K, McNeish IA. CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity. Scientific Reports. 7: 16827. PMID 29203787 DOI: 10.1038/S41598-017-17119-1  0.343
2017 Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, ... ... Murphy DJ, et al. MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nature Communications. 8: 1728. PMID 29170413 DOI: 10.1038/S41467-017-01967-6  0.349
2017 Monteverde T, Tait-Mulder J, Hedley A, Knight JR, Sansom OJ, Murphy DJ. Calcium signalling links MYC to NUAK1. Oncogene. PMID 29106388 DOI: 10.1038/Onc.2017.394  0.378
2016 Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, ... ... Murphy DJ, et al. Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics. Cancer Cell. PMID 28017613 DOI: 10.1016/J.Ccell.2016.11.011  0.346
2016 Iltzsche F, Simon K, Stopp S, Pattschull G, Francke S, Wolter P, Hauser S, Murphy DJ, Garcia P, Rosenwald A, Gaubatz S. An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma. Oncogene. PMID 27212033 DOI: 10.1038/Onc.2016.181  0.391
2015 Murphy DJ, Muthalagu N. BIM's up first. Molecular & Cellular Oncology. 2: e975083. PMID 27308426 DOI: 10.4161/23723556.2014.975083  0.307
2015 Bott AJ, Peng IC, Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, ... Murphy DJ, et al. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metabolism. PMID 26603296 DOI: 10.1016/J.Cmet.2015.09.025  0.406
2015 Monteverde T, Muthalagu N, Port J, Murphy DJ. Evidence of cancer-promoting roles for AMPK and related kinases. The Febs Journal. 282: 4658-71. PMID 26426570 DOI: 10.1111/Febs.13534  0.366
2015 Ichim G, Lopez J, Ahmed SU, Muthalagu N, Giampazolias E, Delgado ME, Haller M, Riley JS, Mason SM, Athineos D, Parsons MJ, van de Kooij B, Bouchier-Hayes L, Chalmers AJ, Rooswinkel RW, ... ... Murphy DJ, et al. Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death. Molecular Cell. 57: 860-72. PMID 25702873 DOI: 10.1016/J.Molcel.2015.01.018  0.315
2015 Neidler S, Murphy DJ. Studying lung cancer progression: insights from genetically engineered mouse models of cancer Lung Cancer Management. 4: 155-157. DOI: 10.2217/Lmt.15.18  0.31
2014 Muthalagu N, Junttila MR, Wiese KE, Wolf E, Morton J, Bauer B, Evan GI, Eilers M, Murphy DJ. BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues. Cell Reports. 8: 1347-53. PMID 25176652 DOI: 10.1016/J.Celrep.2014.07.057  0.36
2014 Kamphorst JJ, Murphy DJ. The 2014 Beatson International Cancer Conference: Powering the Cancer Machine Cancer and Metabolism. 2: 25. DOI: 10.1186/2049-3002-2-25  0.317
2013 Bommert KS, Effenberger M, Leich E, Küspert M, Murphy D, Langer C, Moll R, Janz S, Mottok A, Weissbach S, Rosenwald A, Bargou R, Bommert K. The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival Leukemia. 27: 441-450. PMID 22772059 DOI: 10.1038/Leu.2012.185  0.364
2012 Liu L, Ulbrich J, Müller J, Wüstefeld T, Aeberhard L, Kress TR, Muthalagu N, Rycak L, Rudalska R, Moll R, Kempa S, Zender L, Eilers M, Murphy DJ. Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature. 483: 608-12. PMID 22460906 DOI: 10.1038/Nature10927  0.404
2009 Khanna A, Böckelman C, Hemmes A, Junttila MR, Wiksten JP, Lundin M, Junnila S, Murphy DJ, Evan GI, Haglund C, Westermarck J, Ristimäki A. MYC-dependent regulation and prognostic role of CIP2A in gastric cancer. Journal of the National Cancer Institute. 101: 793-805. PMID 19470954 DOI: 10.1093/Jnci/Djp103  0.382
2008 Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K, Bui DA, Brown-Swigart L, Johnson L, Evan GI. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell. 14: 447-57. PMID 19061836 DOI: 10.1016/J.Ccr.2008.10.018  0.346
2008 Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB, Nasi S, Evan GI. Modelling Myc inhibition as a cancer therapy. Nature. 455: 679-83. PMID 18716624 DOI: 10.1038/Nature07260  0.395
2008 Golipour A, Myers D, Seagroves T, Murphy D, Evan GI, Donoghue DJ, Moorehead RA, Porter LA. The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis. Cancer Research. 68: 3591-600. PMID 18483240 DOI: 10.1158/0008-5472.Can-07-6453  0.388
2008 Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG. Inhibition of cyclin D1 gene transcription by Brg-1. Cell Cycle (Georgetown, Tex.). 7: 647-55. PMID 18239461 DOI: 10.4161/Cc.7.5.5446  0.608
2005 Evan GI, Christophorou M, Lawlor EA, Ringshausen I, Prescott J, Dansen T, Finch A, Martins C, Murphy D. Oncogene-dependent tumor suppression: Using the dark side of the force for cancer therapy Cold Spring Harbor Symposia On Quantitative Biology. 70: 263-273. PMID 16869762 DOI: 10.1101/Sqb.2005.70.054  0.38
2004 Flores I, Murphy DJ, Swigart LB, Knies U, Evan GI. Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia. Oncogene. 23: 5923-30. PMID 15208685 DOI: 10.1038/Sj.Onc.1207796  0.378
2004 Murphy DJ, Swigart LB, Israel MA, Evan GI. Id2 is dispensable for Myc-induced epidermal neoplasia. Molecular and Cellular Biology. 24: 2083-90. PMID 14966287 DOI: 10.1128/Mcb.24.5.2083-2090.2004  0.426
2001 Deeble PD, Murphy DJ, Parsons SJ, Cox ME. Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells. Molecular and Cellular Biology. 21: 8471-82. PMID 11713282 DOI: 10.1128/Mcb.21.24.8471-8482.2001  0.341
1999 Murphy DJ, Hardy S, Engel DA. Human SWI-SNF component BRG1 represses transcription of the c-fos gene. Molecular and Cellular Biology. 19: 2724-33. PMID 10082538 DOI: 10.1128/Mcb.19.4.2724  0.604
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