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Aaron C. Goldstrohm, Ph.D. - Publications

Affiliations: 
2001 Duke University, Durham, NC 
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 McKenney KM, Connacher RP, Dunshee EB, Goldstrohm AC. Chemi-Northern: a versatile chemiluminescent northern blot method for analysis and quantitation of RNA molecules. Rna (New York, N.Y.). PMID 38282416 DOI: 10.1261/rna.079880.123  0.397
2023 McKenney KM, Connacher RP, Dunshee EB, Goldstrohm AC. Chemi-Northern: a versatile chemiluminescent northern blot method for analysis and quantitation of RNA molecules. Biorxiv : the Preprint Server For Biology. PMID 37873431 DOI: 10.1101/2023.10.10.561763  0.392
2023 Arvola RM, Goldstrohm AC. Measuring Poly-Adenosine Tail Length of RNAs by High-Resolution Northern Blotting Coupled with RNase H Cleavage. Methods in Molecular Biology (Clifton, N.J.). 2723: 93-111. PMID 37824066 DOI: 10.1007/978-1-0716-3481-3_6  0.363
2023 Haugen RJ, Barnier C, Elrod ND, Luo H, Jensen MK, Ji P, Smibert CA, Lipshitz HD, Wagner EJ, Freddolino PL, Goldstrohm AC. Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase. Biorxiv : the Preprint Server For Biology. PMID 37693497 DOI: 10.1101/2023.08.29.555372  0.651
2022 Haugen RJ, Arvola RM, Connacher RP, Roden RT, Goldstrohm AC. A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4-NOT deadenylase complex subunits to repress target mRNAs. The Journal of Biological Chemistry. 298: 102270. PMID 35850301 DOI: 10.1016/j.jbc.2022.102270  0.5
2021 Enwerem III, Elrod ND, Chang CT, Lin A, Ji P, Bohn JA, Levdansky Y, Wagner EJ, Valkov E, Goldstrohm A. Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. Rna (New York, N.Y.). PMID 33397688 DOI: 10.1261/rna.078436.120  0.678
2020 Abshire ET, Hughes KL, Diao R, Pearce S, Gopalakrishna S, Trievel RC, Rorbach J, Freddolino PL, Goldstrohm AC. Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors. The Journal of Biological Chemistry. PMID 32839274 DOI: 10.1074/Jbc.Ra120.012618  0.384
2020 Wolfe MB, Schagat TL, Paulsen MT, Magnuson B, Ljungman M, Park D, Zhang C, Campbell ZT, Goldstrohm AC, Freddolino PL. Principles of mRNA control by human PUM proteins elucidated from multi-modal experiments and integrative data analysis. Rna (New York, N.Y.). PMID 32753408 DOI: 10.1261/Rna.077362.120  0.541
2020 Connacher RP, Goldstrohm AC. Molecular and biological functions of TRIM-NHL RNA-binding proteins. Wiley Interdisciplinary Reviews. Rna. e1620. PMID 32738036 DOI: 10.1002/wrna.1620  0.477
2019 Arvola RM, Chang CT, Buytendorp JP, Levdansky Y, Valkov E, Freddolino PL, Goldstrohm AC. Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs. Nucleic Acids Research. PMID 31863588 DOI: 10.1093/Nar/Gkz1187  0.55
2019 Qiu C, Goldstrohm AC, Tanaka Hall TM. Preparation of cooperative RNA recognition complexes for crystallographic structural studies. Methods in Enzymology. 623: 1-22. PMID 31239042 DOI: 10.1016/Bs.Mie.2019.04.001  0.532
2019 Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes & Development. PMID 31171704 DOI: 10.1101/Gad.324715.119  0.429
2019 Wagner EJ, Goldstrohm AC. Biochemical and Next Generation Sequencing Approaches to Study RNA Regulation. Methods (San Diego, Calif.). 155: 1-2. PMID 30797262 DOI: 10.1016/J.Ymeth.2019.02.012  0.604
2019 Lai WS, Arvola RM, Goldstrohm AC, Blackshear PJ. Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover. Methods (San Diego, Calif.). PMID 30625384 DOI: 10.1016/J.Ymeth.2019.01.003  0.462
2018 Wolfe MB, Goldstrohm AC, Freddolino PL. Global analysis of RNA metabolism using bio-orthogonal labeling coupled with next-generation RNA sequencing. Methods (San Diego, Calif.). PMID 30529548 DOI: 10.1016/J.Ymeth.2018.12.001  0.497
2018 Goldstrohm AC, Hall TMT, McKenney KM. Post-transcriptional Regulatory Functions of Mammalian Pumilio Proteins. Trends in Genetics : Tig. PMID 30316580 DOI: 10.1016/J.Tig.2018.09.006  0.512
2018 Hughes KL, Abshire ET, Goldstrohm AC. Regulatory Roles of Vertebrate Nocturnin: Insights and Remaining Mysteries. Rna Biology. PMID 30257600 DOI: 10.1080/15476286.2018.1526541  0.53
2018 T Abshire E, Chasseur J, Bohn JA, Del Rizzo PA, Freddolino PL, Goldstrohm AC, Trievel RC. The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells. Nucleic Acids Research. PMID 29860338 DOI: 10.1093/Nar/Gky412  0.511
2017 Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd PK. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications. 8: 2005. PMID 29222490 DOI: 10.1038/S41467-017-02200-0  0.342
2017 Bohn JA, Van Etten JL, Schagat TL, Bowman BM, McEachin RC, Freddolino PL, Goldstrohm AC. Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins. Nucleic Acids Research. PMID 29165587 DOI: 10.1093/Nar/Gkx1120  0.538
2017 Arvola RM, Weidmann CA, Tanaka Hall TM, Goldstrohm AC. Combinatorial Control of Messenger RNAs by Pumilio, Nanos and Brain Tumor Proteins. Rna Biology. 0. PMID 28318367 DOI: 10.1080/15476286.2017.1306168  0.53
2016 Lou TF, Weidmann CA, Killingsworth J, Tanaka Hall TM, Goldstrohm AC, Campbell ZT. Integrated analysis of RNA-binding protein complexes using in vitro selection and high-throughput sequencing and sequence specificity landscapes (SEQRS). Methods (San Diego, Calif.). PMID 27729296 DOI: 10.1016/J.Ymeth.2016.10.001  0.496
2016 Weidmann CA, Qiu C, Arvola RM, Lou TF, Killingsworth J, Campbell ZT, Tanaka Hall TM, Goldstrohm AC. Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio. Elife. 5. PMID 27482653 DOI: 10.7554/Elife.17096  0.559
2016 Kearse MG, Green KM, Krans A, Rodriguez CM, Linsalata AE, Goldstrohm AC, Todd PK. CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins. Molecular Cell. PMID 27041225 DOI: 10.1016/J.Molcel.2016.02.034  0.416
2016 Weidmann CA, Qiu C, Arvola RM, Lou T, Killingsworth J, Campbell ZT, Hall TMT, Goldstrohm AC. Author response: Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio Elife. DOI: 10.7554/Elife.17096.041  0.447
2014 Weidmann CA, Raynard NA, Blewett NH, Van Etten J, Goldstrohm AC. The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation. Rna (New York, N.Y.). 20: 1298-319. PMID 24942623 DOI: 10.1261/Rna.046029.114  0.547
2014 Hrit J, Raynard N, Van Etten J, Sankar K, Petterson A, Goldstrohm AC. In vitro analysis of RNA degradation catalyzed by deadenylase enzymes. Methods in Molecular Biology (Clifton, N.J.). 1125: 325-39. PMID 24590800 DOI: 10.1007/978-1-62703-971-0_26  0.471
2013 Van Etten J, Schagat TL, Goldstrohm AC. A guide to design and optimization of reporter assays for 3' untranslated region mediated regulation of mammalian messenger RNAs. Methods (San Diego, Calif.). 63: 110-8. PMID 23643865 DOI: 10.1016/J.Ymeth.2013.04.020  0.581
2012 Van Etten J, Schagat TL, Hrit J, Weidmann CA, Brumbaugh J, Coon JJ, Goldstrohm AC. Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs. The Journal of Biological Chemistry. 287: 36370-83. PMID 22955276 DOI: 10.1074/Jbc.M112.373522  0.612
2012 Blewett NH, Goldstrohm AC. A eukaryotic translation initiation factor 4E-binding protein promotes mRNA decapping and is required for PUF repression. Molecular and Cellular Biology. 32: 4181-94. PMID 22890846 DOI: 10.1128/Mcb.00483-12  0.544
2012 Weidmann CA, Goldstrohm AC. Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumor. Molecular and Cellular Biology. 32: 527-40. PMID 22064486 DOI: 10.1128/Mcb.06052-11  0.574
2011 Blewett N, Coller J, Goldstrohm A. A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR. Rna (New York, N.Y.). 17: 535-43. PMID 21220548 DOI: 10.1261/Rna.2436411  0.481
2009 Suh N, Crittenden SL, Goldstrohm A, Hook B, Thompson B, Wickens M, Kimble J. FBF and its dual control of gld-1 expression in the Caenorhabditis elegans germline. Genetics. 181: 1249-60. PMID 19221201 DOI: 10.1534/Genetics.108.099440  0.449
2008 Goldstrohm AC, Hook BA, Wickens M. Regulated deadenylation in vitro. Methods in Enzymology. 448: 77-106. PMID 19111172 DOI: 10.1016/S0076-6879(08)02605-0  0.599
2008 Goldstrohm AC, Wickens M. Multifunctional deadenylase complexes diversify mRNA control. Nature Reviews. Molecular Cell Biology. 9: 337-44. PMID 18334997 DOI: 10.1038/Nrm2370  0.442
2007 Hook BA, Goldstrohm AC, Seay DJ, Wickens M. Two yeast PUF proteins negatively regulate a single mRNA. The Journal of Biological Chemistry. 282: 15430-8. PMID 17389596 DOI: 10.1074/Jbc.M611253200  0.522
2007 Goldstrohm AC, Seay DJ, Hook BA, Wickens M. PUF protein-mediated deadenylation is catalyzed by Ccr4p. The Journal of Biological Chemistry. 282: 109-14. PMID 17090538 DOI: 10.1074/Jbc.M609413200  0.522
2006 Sánchez-Alvarez M, Goldstrohm AC, Garcia-Blanco MA, Suñé C. Human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions. Molecular and Cellular Biology. 26: 4998-5014. PMID 16782886 DOI: 10.1128/Mcb.01991-05  0.636
2006 Goldstrohm AC, Hook BA, Seay DJ, Wickens M. PUF proteins bind Pop2p to regulate messenger RNAs. Nature Structural & Molecular Biology. 13: 533-9. PMID 16715093 DOI: 10.1038/Nsmb1100  0.564
2003 Wickens M, Goldstrohm A. Molecular biology. A place to die, a place to sleep. Science (New York, N.Y.). 300: 753-5. PMID 12730589 DOI: 10.1126/Science.1084512  0.328
2001 Goldstrohm AC, Albrecht TR, Suñé C, Bedford MT, Garcia-Blanco MA. The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. Molecular and Cellular Biology. 21: 7617-28. PMID 11604498 DOI: 10.1128/Mcb.21.22.7617-7628.2001  0.61
2001 Goldstrohm AC, Greenleaf AL, Garcia-Blanco MA. Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. Gene. 277: 31-47. PMID 11602343 DOI: 10.1016/S0378-1119(01)00695-3  0.65
2000 Suñé C, Goldstrohm AC, Peng J, Price DH, Garcia-Blanco MA. An in vitro transcription system that recapitulates equine infectious anemia virus tat-mediated inhibition of human immunodeficiency virus type 1 Tat activity demonstrates a role for positive transcription elongation factor b and associated proteins in the mechanism of Tat activation. Virology. 274: 356-66. PMID 10964778 DOI: 10.1006/Viro.2000.0480  0.552
2000 Carty SM, Goldstrohm AC, Suñé C, Garcia-Blanco MA, Greenleaf AL. Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 97: 9015-20. PMID 10908677 DOI: 10.1073/Pnas.160266597  0.626
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