Tim M. Delorey - Publications

Affiliations: 
Molecular Research Institute, Palo Alto, Sunnyvale, CA, United States 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 DeLorey TM, Sahbaie P, Hashemi E, Li WW, Salehi A, Clark DJ. Somatosensory and sensorimotor consequences associated with the heterozygous disruption of the autism candidate gene, Gabrb3. Behavioural Brain Research. 216: 36-45. PMID 20699105 DOI: 10.1016/j.bbr.2010.06.032  0.44
2010 Tanaka M, Delorey TM, Delgado-Escueta AV, Olsen RW. GABRB3, epilepsy, and neurodevelopment Epilepsia. 51: 77. DOI: 10.1111/j.1528-1167.2010.02863.x  0.44
2008 Harris D, Clayton T, Cook J, Sahbaie P, Halliwell RF, Furtmüller R, Huck S, Sieghart W, DeLorey TM. Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. Journal of Medicinal Chemistry. 51: 3788-803. PMID 18537233 DOI: 10.1021/jm701433b  0.44
2008 DeLorey TM, Sahbaie P, Hashemi E, Homanics GE, Clark JD. Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behavioural Brain Research. 187: 207-20. PMID 17983671 DOI: 10.1016/j.bbr.2007.09.009  0.44
2008 Sahbaie P, Madanlou S, Gharagozlou P, Clark JD, Lameh J, Delorey TM. Transcutaneous blood gas CO2 monitoring of induced ventilatory depression in mice (Anesthesia and Analgesia (2007) 103, (620-625)) Anesthesia and Analgesia. 106: 1325. DOI: 10.1213/ane.0b013e318165e012  0.44
2007 Ferguson C, Hardy SL, Werner DF, Hileman SM, Delorey TM, Homanics GE. New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout. Bmc Neuroscience. 8: 85. PMID 17927825 DOI: 10.1186/1471-2202-8-85  0.44
2007 Hashemi E, Sahbaie P, Davies MF, Clark JD, DeLorey TM. Gabrb3 gene deficient mice exhibit increased risk assessment behavior, hypotonia and expansion of the plexus of locus coeruleus dendrites. Brain Research. 1129: 191-9. PMID 17156762 DOI: 10.1016/j.brainres.2006.10.050  0.44
2006 Sahbaie P, Modanlou S, Madanlou S, Gharagozlou P, Clark JD, Lameh J, Delorey TM. Transcutaneous blood gas CO2 monitoring of induced ventilatory depression in mice. Anesthesia and Analgesia. 103: 620-5. PMID 16931671 DOI: 10.1213/01.ane.0000229714.09553.8c  0.44
2006 Gharagozlou P, Hashemi E, DeLorey TM, Clark JD, Lameh J. Pharmacological profiles of opioid ligands at kappa opioid receptors. Bmc Pharmacology. 6: 3. PMID 16433932 DOI: 10.1186/1471-2210-6-3  0.44
2005 DeLorey TM. GABRB3 gene deficient mice: a potential model of autism spectrum disorder. International Review of Neurobiology. 71: 359-82. PMID 16512358 DOI: 10.1016/S0074-7742(05)71015-1  0.44
2005 Handforth A, Delorey TM, Homanics GE, Olsen RW. Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome. Epilepsia. 46: 1860-70. PMID 16393151 DOI: 10.1111/j.1528-1167.2005.00287.x  0.44
2004 Belmonte MK, Cook EH, Anderson GM, Rubenstein JL, Greenough WT, Beckel-Mitchener A, Courchesne E, Boulanger LM, Powell SB, Levitt PR, Perry EK, Jiang YH, DeLorey TM, Tierney E. Autism as a disorder of neural information processing: directions for research and targets for therapy. Molecular Psychiatry. 9: 646-63. PMID 15037868 DOI: 10.1038/sj.mp.4001499  0.44
2004 Davies MF, Tsui J, Flannery JA, Li X, DeLorey TM, Hoffman BB. Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 229-39. PMID 14583739 DOI: 10.1038/sj.npp.1300324  0.44
2003 Davies MF, Tsui JY, Flannery JA, Li X, DeLorey TM, Hoffman BB. Augmentation of the noradrenergic system in alpha-2 adrenergic receptor deficient mice: anatomical changes associated with enhanced fear memory. Brain Research. 986: 157-65. PMID 12965240 DOI: 10.1016/S0006-8993(03)03248-7  0.44
2002 Wisor JP, DeLorey TM, Homanics GE, Edgar DM. Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor. Brain Research. 955: 221-8. PMID 12419540 DOI: 10.1016/S0006-8993(02)03467-4  0.44
2001 DeLorey TM, Lin RC, McBrady B, He X, Cook JM, Lameh J, Loew GH. Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory. European Journal of Pharmacology. 426: 45-54. PMID 11525770 DOI: 10.1016/S0014-2999(01)01199-2  0.44
2000 Harris DL, DeLorey TM, He X, Cook JM, Loew GH. Determinants of recognition of ligands binding to benzodiazepine receptor/GABA(A) receptors initiating sedation. European Journal of Pharmacology. 401: 271-87. PMID 10936485 DOI: 10.1016/S0014-2999(00)00462-3  0.44
2000 Gordey M, DeLorey TM, Olsen RW. Differential sensitivity of recombinant GABA(A) receptors expressed in Xenopus oocytes to modulation by topiramate. Epilepsia. 41: S25-9. PMID 10768296  0.44
1999 Mihalek RM, Banerjee PK, Korpi ER, Quinlan JJ, Firestone LL, Mi ZP, Lagenaur C, Tretter V, Sieghart W, Anagnostaras SG, Sage JR, Fanselow MS, Guidotti A, Spigelman I, Li Z, ... DeLorey TM, et al. Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 12905-10. PMID 10536021 DOI: 10.1073/pnas.96.22.12905  0.44
1999 DeLorey TM, Olsen RW. GABA and epileptogenesis: comparing gabrb3 gene-deficient mice with Angelman syndrome in man. Epilepsy Research. 36: 123-32. PMID 10515160 DOI: 10.1016/S0920-1211(99)00046-7  0.44
1999 Olsen RW, DeLorey TM, Gordey M, Kang MH. GABA receptor function and epilepsy. Advances in Neurology. 79: 499-510. PMID 10514838  0.44
1999 Lalande M, Minassian BA, DeLorey TM, Olsen RW. Parental imprinting and Angelman syndrome. Advances in Neurology. 79: 421-9. PMID 10514831  0.44
1999 Huntsman MM, Porcello DM, Homanics GE, DeLorey TM, Huguenard JR. Reciprocal inhibitory connections and network synchrony in the mammalian thalamus. Science (New York, N.Y.). 283: 541-3. PMID 9915702 DOI: 10.1126/science.283.5401.541  0.44
1998 DeLorey TM, Handforth A, Anagnostaras SG, Homanics GE, Minassian BA, Asatourian A, Fanselow MS, Delgado-Escueta A, Ellison GD, Olsen RW. Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8505-14. PMID 9763493  0.44
1998 Minassian BA, DeLorey TM, Olsen RW, Philippart M, Bronstein Y, Zhang Q, Guerrini R, Van Ness P, Livet MO, Delgado-Escueta AV. Angelman syndrome: correlations between epilepsy phenotypes and genotypes. Annals of Neurology. 43: 485-93. PMID 9546330 DOI: 10.1002/ana.410430412  0.44
1997 Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proceedings of the National Academy of Sciences of the United States of America. 94: 4143-8. PMID 9108119 DOI: 10.1073/pnas.94.8.4143  0.44
1995 Greger V, Knoll JH, Woolf E, Glatt K, Tyndale RF, DeLorey TM, Olsen RW, Tobin AJ, Sikela JM, Nakatsu Y. The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3) is tightly linked to the alpha 5 subunit gene (GABRA5) on human chromosome 15q11-q13 and is transcribed in the same orientation. Genomics. 26: 258-64. PMID 7601451 DOI: 10.1016/0888-7543(95)80209-5  0.44
1995 Huh KH, Delorey TM, Endo S, Olsen RW. Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies. Molecular Pharmacology. 48: 666-75. PMID 7476892  0.44
1994 Brouillette WJ, Jestkov VP, Brown ML, Akhtar MS, DeLorey TM, Brown GB. Bicyclic hydantoins with a bridgehead nitrogen. Comparison of anticonvulsant activities with binding to the neuronal voltage-dependent sodium channel. Journal of Medicinal Chemistry. 37: 3289-93. PMID 7932556  0.44
1993 DeLorey TM, Kissin I, Brown P, Brown GB. Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acidA receptor in rat cerebral cortical synaptoneurosomes. Anesthesia and Analgesia. 77: 598-605. PMID 8396370  0.44
1993 Nakatsu Y, Tyndale RF, DeLorey TM, Durham-Pierre D, Gardner JM, McDanel HJ, Nguyen Q, Wagstaff J, Lalande M, Sikela JM. A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Nature. 364: 448-50. PMID 8392662 DOI: 10.1038/364448a0  0.44
1992 DeLorey TM, Olsen RW. Gamma-aminobutyric acidA receptor structure and function. The Journal of Biological Chemistry. 267: 16747-50. PMID 1380954  0.44
1992 DeLorey TM, Brown GB. gamma-Aminobutyric acidA receptor pharmacology in rat cerebral cortical synaptoneurosomes. Journal of Neurochemistry. 58: 2162-9. PMID 1315378  0.44
1990 Brouillette WJ, Brown GB, DeLorey TM, Liang G. Sodium channel binding and anticonvulsant activities of hydantoins containing conformationally constrained 5-phenyl substituents. Journal of Pharmaceutical Sciences. 79: 871-4. PMID 2177789  0.44
1989 Brouillette WJ, Grunewald GL, Brown GB, DeLorey TM, Akhtar MS, Liang G. Sodium channel binding and anticonvulsant activities for the enantiomers of a bicyclic 2,4-oxazolidinedione and monocyclic models. Journal of Medicinal Chemistry. 32: 1577-80. PMID 2544727  0.44
1988 Brouillette WJ, Brown GB, DeLorey TM, Shirali SS, Grunewald GL. Anticonvulsant activities of phenyl-substituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel. Journal of Medicinal Chemistry. 31: 2218-21. PMID 2846842  0.44
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