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Jeffrey M. Friedman - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
molecular mechanisms that regulate food intake and body weight
Website:
http://www.rockefeller.edu/research/faculty/abstract.php?id=41

478 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ortuno MJ, Schneeberger M, Ilanges A, Marchildon F, Pellegrino K, Friedman JM, Ducy P. Melanocortin 4 receptor stimulation prevents anti-depressant-associated weight gain in mice caused by long-term fluoxetine exposure. The Journal of Clinical Investigation. PMID 34673574 DOI: 10.1172/JCI151976  1
2021 Azevedo EP, Ivan VJ, Friedman JM, Stern SA. Higher-Order Inputs Involved in Appetite Control. Biological Psychiatry. PMID 34593204 DOI: 10.1016/j.biopsych.2021.07.015  1
2021 Parolari L, Schneeberger M, Heintz N, Friedman JM. Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson's disease and OCD-like behaviors in mice. Molecular Psychiatry. PMID 34099874 DOI: 10.1038/s41380-021-01162-6  1
2021 Ito K, Schneeberger M, Gerber A, Jishage M, Marchildon F, Maganti AV, Cohen P, Friedman JM, Roeder RG. Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues. Genes & Development. PMID 33888560 DOI: 10.1101/gad.346791.120  1
2021 Stern SA, Azevedo EP, Pomeranz LE, Doerig KR, Ivan VJ, Friedman JM. Top-down control of conditioned overconsumption is mediated by insular cortex Nos1 neurons. Cell Metabolism. PMID 33761312 DOI: 10.1016/j.cmet.2021.03.001  1
2020 Assis AM, Friedman JM, Velloso LA. Gut-to-brain signals in feeding control. American Journal of Physiology. Endocrinology and Metabolism. PMID 33284086 DOI: 10.1152/ajpendo.00388.2020  0.04
2020 Azevedo EP, Tan B, Pomeranz LE, Ivan V, Fetcho R, Schneeberger M, Doerig KR, Liston C, Friedman JM, Stern SA. A limbic circuit selectively links active escape to food suppression. Elife. 9. PMID 32894221 DOI: 10.7554/Elife.58894  1
2020 Tao P, Kuang Y, Li Y, Li W, Gao Z, Liu L, Qiang M, Zha Z, Fan K, Ma P, Friedman JM, Yang G, Lerner RA. Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2000818. PMID 32832353 DOI: 10.1002/Advs.202000818  1
2020 Brier MI, Mundell JW, Yu X, Su L, Holmann A, Squeri J, Zhang B, Stanley SA, Friedman JM, Dordick JS. Uncovering a possible role of reactive oxygen species in magnetogenetics. Scientific Reports. 10: 13096. PMID 32753716 DOI: 10.1038/S41598-020-70067-1  1
2020 Wang P, Loh KH, Wu M, Morgan DA, Schneeberger M, Yu X, Chi J, Kosse C, Kim D, Rahmouni K, Cohen P, Friedman J. A leptin-BDNF pathway regulating sympathetic innervation of adipose tissue. Nature. PMID 32699414 DOI: 10.1038/S41586-020-2527-Y  1
2020 Hedbacker K, Lu YH, Dallner O, Li Z, Fayzikhodjaeva G, Birsoy K, Han C, Yang C, Friedman JM. Limitation of adipose tissue by the number of embryonic progenitor cells. Elife. 9. PMID 32452759 DOI: 10.7554/Elife.53074  1
2020 Azevedo EP, Tan B, Pomeranz LE, Ivan V, Fetcho R, Schneeberger M, Doerig KR, Liston C, Friedman JM, Stern SA. Author response: A limbic circuit selectively links active escape to food suppression Elife. DOI: 10.7554/Elife.58894.Sa2  1
2020 Hedbacker K, Lu Y, Dallner O, Li Z, Fayzikhodjaeva G, Birsoy K, Han C, Yang C, Friedman JM. Author response: Limitation of adipose tissue by the number of embryonic progenitor cells Elife. DOI: 10.7554/Elife.53074.Sa2  1
2020 Stern S, Pomeranz L, Azevedo E, Doerig K, Friedman J. A Molecularly Defined Insular to Central Amygdala Circuit Controls Conditioned Overconsumption Biological Psychiatry. 87: S136. DOI: 10.1016/J.Biopsych.2020.02.363  0.01
2019 Friedman JM. Leptin and the endocrine control of energy balance. Nature Metabolism. 1: 754-764. PMID 32694767 DOI: 10.1038/s42255-019-0095-y  0.01
2019 Schneeberger M, Parolari L, Das Banerjee T, Bhave V, Wang P, Patel B, Topilko T, Wu Z, Choi CHJ, Yu X, Pellegrino K, Engel EA, Cohen P, Renier N, Friedman JM, et al. Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell. PMID 31257028 DOI: 10.1016/J.Cell.2019.05.048  1
2019 Azevedo EP, Pomeranz L, Cheng J, Schneeberger M, Vaughan R, Stern SA, Tan B, Doerig K, Greengard P, Friedman JM. A Role of Drd2 Hippocampal Neurons in Context-Dependent Food Intake. Neuron. PMID 30930044 DOI: 10.1016/J.Neuron.2019.03.011  1
2019 Dallner OS, Marinis JM, Lu YH, Birsoy K, Werner E, Fayzikhodjaeva G, Dill BD, Molina H, Moscati A, Kutalik Z, Marques-Vidal P, Kilpeläinen TO, Grarup N, Linneberg A, Zhang Y, ... ... Friedman JM, et al. Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity. Nature Medicine. PMID 30842678 DOI: 10.1038/S41591-019-0370-1  1
2018 Zhang H, Chaudhury D, Nectow AR, Friedman AK, Zhang S, Juarez B, Liu H, Pfau ML, Aleyasin H, Jiang C, Crumiller M, Calipari ES, Ku SM, Morel C, Tzavaras N, ... ... Friedman JM, et al. α- and β-Adrenergic Receptor-Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice. Biological Psychiatry. PMID 30336931 DOI: 10.1016/J.Biopsych.2018.08.020  1
2018 Stanley SA, Friedman JM. Electromagnetic Regulation of Cell Activity. Cold Spring Harbor Perspectives in Medicine. PMID 30249601 DOI: 10.1101/cshperspect.a034322  1
2018 Tabansky I, Liang Y, Frankfurt M, Daniels MA, Harrigan M, Stern S, Milner TA, Leshan R, Rama R, Moll T, Friedman JM, Stern JNH, Pfaff DW. Molecular profiling of reticular gigantocellularis neurons indicates that eNOS modulates environmentally dependent levels of arousal. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967172 DOI: 10.1073/Pnas.1806123115  1
2018 Zhang Y, Dallner OS, Nakadai T, Fayzikhodjaeva G, Lu YH, Lazar MA, Roeder RG, Friedman JM. A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891714 DOI: 10.1073/Pnas.1806366115  1
2018 Stern SA, Doerig KR, Azevedo EP, Stoffel E, Friedman JM. Control of non-homeostatic feeding in sated mice using associative learning of contextual food cues. Molecular Psychiatry. PMID 29875477 DOI: 10.1038/S41380-018-0072-Y  1
2018 Schneeberger M, Tan K, Nectow AR, Parolari L, Caglar C, Azevedo E, Li Z, Domingos A, Friedman JM. Functional analysis reveals differential effects of glutamate and MCH neuropeptide in MCH neurons. Molecular Metabolism. PMID 29843980 DOI: 10.1016/J.Molmet.2018.05.001  1
2018 Calarco CA, Li Z, Taylor SR, Lee S, Zhou W, Friedman JM, Mineur YS, Gotti C, Picciotto MR. Molecular and cellular characterization of nAChR subtypes in the arcuate nucleus of the mouse hypothalamus. The European Journal of Neuroscience. PMID 29791746 DOI: 10.1111/Ejn.13966  1
2017 Nectow AR, Schneeberger M, Zhang H, Field BC, Renier N, Azevedo E, Patel B, Liang Y, Mitra S, Tessier-Lavigne M, Han MH, Friedman JM. Identification of a Brainstem Circuit Controlling Feeding. Cell. 170: 429-442.e11. PMID 28753423 DOI: 10.1016/J.Cell.2017.06.045  1
2017 Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/J.Celrep.2017.03.048  1
2017 Pomeranz LE, Ekstrand MI, Latcha KN, Smith GA, Enquist LW, Friedman JM. Gene expression profiling with Cre-conditional pseudorabies virus reveals a subset of midbrain neurons that participate in reward circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28283558 DOI: 10.1523/Jneurosci.3193-16.2017  1
2016 Friedman J. The long road to leptin. Journal of Clinical Investigation. 126: 4727-4734. PMID 27906690 DOI: 10.1172/Jci91578  0.01
2016 Sanchez-Rodriguez SP, Sauer JP, Stanley SA, Qian X, Gottesdiener A, Friedman JM, Dordick JS. Plasmonic activation of gold nanorods for remote stimulation of calcium signaling and protein expression in HEK 293T cells. Biotechnology and Bioengineering. 113: 2228-2240. PMID 27563853 DOI: 10.1002/Bit.25984  1
2016 Stanley SA, Kelly L, Latcha KN, Schmidt SF, Yu X, Nectow AR, Sauer J, Dyke JP, Dordick JS, Friedman JM. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature. PMID 27007848 DOI: 10.1038/Nature17183  1
2016 Sanchez-Rodriguez SP, Sauer JP, Stanley SA, Qian X, Gottesdiener A, Friedman JM, Dordick JS. Plasmonic activation of gold nanorods for remote stimulation of calcium signaling and protein expression in HEK 293T cells Biotechnology and Bioengineering. DOI: 10.1002/bit.25984  1
2015 Li Z, Kelly L, Heiman M, Greengard P, Friedman JM. Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. Cell Metabolism. 22: 1059-67. PMID 26655697 DOI: 10.1016/J.Cmet.2015.10.012  1
2015 Friedman J. Leptin and the Regulation of Food Intake and Body Weight. Journal of Nutritional Science and Vitaminology. 61: S202. PMID 26598860 DOI: 10.3177/Jnsv.61.S202  1
2015 Chitty LS, Friedman JM, Langlois S. Current Controversies in Prenatal Diagnosis 2: Should a fetal exome be used in the assessment of a dysmorphic or malformed fetus? Prenatal Diagnosis. PMID 26525746 DOI: 10.1002/pd.4718  1
2015 Tanowitz HB, Machado FS, Spray DC, Friedman JM, Weiss OS, Lora JN, Nagajyothi J, Moraes DN, Garg NJ, Nunes MC, Ribeiro AL. Developments in the management of Chagas cardiomyopathy. Expert Review of Cardiovascular Therapy. 1-17. PMID 26496376 DOI: 10.1586/14779072.2015.1103648  1
2015 Zeng W, Pirzgalska RM, Pereira MM, Kubasova N, Barateiro A, Seixas E, Lu YH, Kozlova A, Voss H, Martins GG, Friedman JM, Domingos AI. Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis. Cell. 163: 84-94. PMID 26406372 DOI: 10.1016/J.Cell.2015.08.055  1
2015 Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/J.Chembiol.2015.07.011  1
2015 Hexter A, Jones A, Joe H, Heap L, Smith MJ, Wallace AJ, Halliday D, Parry A, Taylor A, Raymond L, Shaw A, Afridi S, Obholzer R, Axon P, King AT, ... Friedman JM, et al. Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients. Journal of Medical Genetics. PMID 26275417 DOI: 10.1136/jmedgenet-2015-103290  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405]. Molecular Metabolism. 4: 592. PMID 26266092 DOI: 10.1016/J.Molmet.2015.05.004  1
2015 Nectow AR, Ekstrand MI, Friedman JM. Molecular characterization of neuronal cell types based on patterns of projection with Retro-TRAP. Nature Protocols. 10: 1319-27. PMID 26247298 DOI: 10.1038/Nprot.2015.087  1
2015 Qin M, Landriscina A, Rosen J, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler B, Krausz A, Friedman J, Nosanchuk J, et al. Nitric Oxide Releasing Nanoparticles Prevent Propionibacterium acnes Induced Inflammation by both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. The Journal of Investigative Dermatology. PMID 26172313 DOI: 10.1038/Jid.2015.277  1
2015 Reefhuis J, Devine O, Friedman JM, Louik C, Honein MA. Specific SSRIs and birth defects: Bayesian analysis to interpret new data in the context of previous reports. Bmj (Clinical Research Ed.). 351: h3190. PMID 26156519 DOI: 10.1136/bmj.h3190  1
2015 Zeng W, Lu YH, Lee J, Friedman JM. Reanalysis of parabiosis of obesity mutants in the age of leptin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150485 DOI: 10.1073/Pnas.1510378112  1
2015 Ning X, Farschtschi S, Jones A, Kehrer-Sawatzki H, Mautner VF, Friedman JM. Growth in Neurofibromatosis 1 Microdeletion Patients. Clinical Genetics. PMID 26111455 DOI: 10.1111/cge.12632  1
2015 Friedman JM. Editorial. Life Sciences. PMID 26092482 DOI: 10.1016/j.lfs.2015.06.002  1
2015 Adam S, Friedman JM. Individual DNA samples and health information sold by 23andMe. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 26087174 DOI: 10.1038/gim.2015.82  1
2015 Battula KK, Nappanveettil G, Nakanishi S, Kuramoto T, Friedman JM, Kalashikam RR. Genetic Relatedness of WNIN and WNIN/Ob with Major Rat Strains in Biomedical Research. Biochemical Genetics. 53: 132-40. PMID 25991561 DOI: 10.1007/s10528-015-9679-8  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression. Molecular Metabolism. 4: 392-405. PMID 25973387 DOI: 10.1016/J.Molmet.2015.02.002  1
2015 Boycott K, Hartley T, Adam S, Bernier F, Chong K, Fernandez BA, Friedman JM, Geraghty MT, Hume S, Knoppers BM, Laberge AM, Majewski J, Mendoza-Londono R, Meyn MS, Michaud JL, et al. The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists. Journal of Medical Genetics. 52: 431-7. PMID 25951830 DOI: 10.1136/Jmedgenet-2015-103144  1
2015 Bajou K, Herkenne S, Thijssen VL, D'Amico S, Nguyen NQ, Bouché A, Tabruyn S, Srahna M, Carabin JY, Nivelles O, Paques C, Cornelissen I, Lion M, Noel A, Gils A, et al. Corrigendum: PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin. Nature Medicine. 21: 537. PMID 25951534 DOI: 10.1038/Nm0515-537A  0.04
2015 Stanley SA, Sauer J, Kane RS, Dordick JS, Friedman JM. Corrigendum: Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nature Medicine. 21: 537. PMID 25951532 DOI: 10.1038/Nm0515-537B  1
2015 Jett K, Nguyen R, Arman D, Birch P, Chohan H, Farschtschi S, Fuensterer C, Kluwe L, Friedman JM, Mautner VF. Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1. American Journal of Medical Genetics. Part A. 167: 1518-24. PMID 25900062 DOI: 10.1002/ajmg.a.37068  1
2015 Samuels ME, Friedman JM. Genetic mosaics and the germ line lineage. Genes. 6: 216-37. PMID 25898403 DOI: 10.3390/genes6020216  1
2015 Charafeddine RA, Makdisi J, Schairer D, O'Rourke BP, Diaz-Valencia JD, Chouake J, Kutner A, Krausz A, Adler B, Nacharaju P, Liang H, Mukherjee S, Friedman JM, Friedman A, Nosanchuk JD, et al. Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing. The Journal of Investigative Dermatology. PMID 25756798 DOI: 10.1038/jid.2015.94  1
2015 Filges I, Manokhina I, Peñaherrera MS, McFadden DE, Louie K, Nosova E, Friedman JM, Robinson WP. Recurrent triploidy due to a failure to complete maternal meiosis II: whole-exome sequencing reveals candidate variants. Molecular Human Reproduction. 21: 339-46. PMID 25504873 DOI: 10.1093/molehr/gau112  1
2015 Stanley SA, Sauer J, Kane RS, Dordick JS, Friedman JM. Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nature Medicine. 21: 92-8. PMID 25501906 DOI: 10.1038/Nm.3730  1
2015 Friedman JM, Mantzoros CS. 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. Metabolism: Clinical and Experimental. 64: 1-4. PMID 25497341 DOI: 10.1016/J.Metabol.2014.10.023  1
2015 Mordorski B, Pelgrift R, Adler B, Krausz A, da Costa Neto AB, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Nacharaju P, Friedman AJ. S-nitrosocaptopril nanoparticles as nitric oxide-liberating and transnitrosylating anti-infective technology. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 283-91. PMID 25461287 DOI: 10.1016/j.nano.2014.09.017  1
2015 Roche CJ, Talwar A, Palmer AF, Cabrales P, Gerfen G, Friedman JM. Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties. The Journal of Biological Chemistry. 290: 99-117. PMID 25371199 DOI: 10.1074/Jbc.M114.583260  1
2015 Krausz AE, Adler BL, Cabral V, Navati M, Doerner J, Charafeddine RA, Chandra D, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Friedman AJ. Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 195-206. PMID 25240595 DOI: 10.1016/J.Nano.2014.09.004  1
2015 Berkunsky I, Simoy MV, Cepeda RE, Marinelli C, Kacoliris FP, Daniele G, Cortelezzi A, Díaz-Luque JA, Friedman JM, Aramburú RM. Assessing the use of forest islands by parrot species in a neotropical savanna | Évaluation de l'utilisation d'îles forestières par des espèces de perroquets dans une savane néotropicale Avian Conservation and Ecology. 10. DOI: 10.5751/ACE-00753-100111  1
2015 Meko DM, Friedman JM, Touchan R, Edmondson JR, Griffin ER, Scott JA. Alternative standardization approaches to improving streamflow reconstructions with ring-width indices of riparian trees Holocene. 25: 1093-1101. DOI: 10.1177/0959683615580181  1
2015 Friedman JM, Vincent KR, Griffin ER, Scott ML, Shafroth PB, Auble GT. Processes of arroyo filling in northern New Mexico, USA Bulletin of the Geological Society of America. 127: 621-640. DOI: 10.1130/B31046.1  1
2015 Mcshane RR, Auerbach DA, Friedman JM, Auble GT, Shafroth PB, Merigliano MF, Scott ML, Poff NL. Distribution of invasive and native riparian woody plants across the western USA in relation to climate, river flow, floodplain geometry and patterns of introduction Ecography. 38: 1254-1265. DOI: 10.1111/Ecog.01285  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405] Molecular Metabolism. DOI: 10.1016/j.molmet.2015.05.004  1
2015 Sackeyfio R, Bernstein JL, Kutler DI, Friedman JM, Spector JA. Reconstruction of a pathologic mandibular fracture in a patient with pycnodysostosis using a free osteocutaneous fibula flap: A case report Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. DOI: 10.1016/j.ajoms.2015.03.010  1
2015 Nemzer LR, Navati MS, Friedman JM. Imprisoned lightning: charge transport in trehalose-derived sugar glasses Ionics. DOI: 10.1007/s11581-015-1410-6  1
2015 Liu S, Chen Y, Friedman JM, Hati JHA, Fang G. Use of 2H and 18O stable isotopes to investigate water sources for different ages of Populus euphratica along the lower Heihe River Ecological Research. DOI: 10.1007/s11284-015-1270-6  1
2015 Friedman J. Foreword Leptin: Regulation and Clinical Applications. vii-xvi. DOI: 10.1007/978-3-319-09915-6  1
2015 Mandinach EB, Friedman JM, Gummer ES. How can schools of education help to build educators' capacity to use data? A systemic view of the issue Teachers College Record. 117: 1-50.  1
2014 Daston GP, Beyer BK, Carney EW, Chapin RE, Friedman JM, Piersma AH, Rogers JM, Scialli AR. Exposure-based validation list for developmental toxicity screening assays. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 423-8. PMID 25475026 DOI: 10.1002/bdrb.21132  1
2014 Bove R, Alwan S, Friedman JM, Hellwig K, Houtchens M, Koren G, Lu E, McElrath TF, Smyth P, Tremlett H, Sadovnick AD. Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review. Obstetrics and Gynecology. 124: 1157-68. PMID 25415167 DOI: 10.1097/01.Aoa.0000472705.96338.58  1
2014 Stavas MJ, Shinohara ET, Attia A, Ning MS, Friedman JM, Cmelak AJ. Short course high dose radiotherapy in the treatment of anaplastic thyroid carcinoma. Journal of Thyroid Research. 2014: 764281. PMID 25379320 DOI: 10.1155/2014/764281  1
2014 Tan K, Knight ZA, Friedman JM. Ablation of AgRP neurons impairs adaption to restricted feeding. Molecular Metabolism. 3: 694-704. PMID 25352998 DOI: 10.1016/J.Molmet.2014.07.002  1
2014 Friedman JM, Stavas MJ, Cmelak AJ. Clinical and scientific impact of human papillomavirus on head and neck cancer. World Journal of Clinical Oncology. 5: 781-91. PMID 25302178 DOI: 10.5306/wjco.v5.i4.781  1
2014 Elliott JE, Friedman JM, Futral JE, Goodman RD, Lovering AT. Sildenafil, nifedipine and acetazolamide do not allow for blood flow through intrapulmonary arteriovenous anastomoses during exercise while breathing 100% oxygen. Experimental Physiology. 99: 1636-47. PMID 25261497 DOI: 10.1113/Expphysiol.2014.081562  1
2014 Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/Ajmg.A.36754  1
2014 Saito N, Sakakibara K, Sato T, Friedman JM, Kufe DW, VonHoff DD, Kawabe T. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway. Molecular Cancer Therapeutics. 13: 3013-23. PMID 25253782 DOI: 10.1158/1535-7163.MCT-14-0064  1
2014 Knight ZA, Schmidt SF, Birsoy K, Tan K, Friedman JM. A critical role for mTORC1 in erythropoiesis and anemia. Elife. 3: e01913. PMID 25201874 DOI: 10.7554/Elife.01913  1
2014 Friedman J. 20 years of leptin: leptin at 20: an overview. The Journal of Endocrinology. 223: T1-8. PMID 25121999 DOI: 10.1530/Joe-14-0405  1
2014 Filges I, Friedman JM. Exome sequencing for gene discovery in lethal fetal disorders - harnessing the value of extreme phenotypes. Prenatal Diagnosis. PMID 25046514 DOI: 10.1002/pd.4464  1
2014 Liong C, Ortiz D, Ao-ieong E, Navati MS, Friedman JM, Cabrales P. Localized increase of tissue oxygen tension by magnetic targeted drug delivery. Nanotechnology. 25: 265102. PMID 24920392 DOI: 10.1088/0957-4484/25/26/265102  1
2014 Beaulieu CL, Majewski J, Schwartzentruber J, Samuels ME, Fernandez BA, Bernier FP, Brudno M, Knoppers B, Marcadier J, Dyment D, Adam S, Bulman DE, Jones SJ, Avard D, Nguyen MT, ... ... Friedman JM, et al. FORGE Canada Consortium: outcomes of a 2-year national rare-disease gene-discovery project. American Journal of Human Genetics. 94: 809-17. PMID 24906018 DOI: 10.1016/J.Ajhg.2014.05.003  1
2014 Friedman J. Douglas Coleman (1931-2014). Nature. 509: 564. PMID 24870535 DOI: 10.1038/509564A  1
2014 Ekstrand MI, Nectow AR, Knight ZA, Latcha KN, Pomeranz LE, Friedman JM. Molecular profiling of neurons based on connectivity. Cell. 157: 1230-42. PMID 24855954 DOI: 10.1016/J.Cell.2014.03.059  1
2014 Williams WI, Friedman JM, Gaskin JF, Norton AP. Hybridization of an invasive shrub affects tolerance and resistance to defoliation by a biological control agent. Evolutionary Applications. 7: 381-93. PMID 24665340 DOI: 10.1111/eva.12134  1
2014 Friedman JM, Adam S. Genetic diagnosis through whole-exome sequencing. The New England Journal of Medicine. 370: 1067-8. PMID 24620874 DOI: 10.1056/NEJMc1315908#SA2  1
2014 Domingos AI, Vaynshteyn J, Sordillo A, Friedman JM. The reward value of sucrose in leptin-deficient obese mice. Molecular Metabolism. 3: 73-80. PMID 24567906 DOI: 10.1016/J.Molmet.2013.10.007  1
2014 Demos MK, van Karnebeek CD, Ross CJ, Adam S, Shen Y, Zhan SH, Shyr C, Horvath G, Suri M, Fryer A, Jones SJ, Friedman JM. A novel recurrent mutation in ATP1A3 causes CAPOS syndrome. Orphanet Journal of Rare Diseases. 9: 15. PMID 24468074 DOI: 10.1186/1750-1172-9-15  1
2014 Saito Y, Saito H, Liang G, Friedman JM. Epigenetic alterations and microRNA misexpression in cancer and autoimmune diseases: a critical review. Clinical Reviews in Allergy & Immunology. 47: 128-35. PMID 24362548 DOI: 10.1007/s12016-013-8401-z  1
2014 McKinnon ML, Rozmus J, Fung SY, Hirschfeld AF, Del Bel KL, Thomas L, Marr N, Martin SD, Marwaha AK, Priatel JJ, Tan R, Senger C, Tsang A, Prendiville J, Junker AK, ... ... Friedman JM, et al. Combined immunodeficiency associated with homozygous MALT1 mutations. The Journal of Allergy and Clinical Immunology. 133: 1458-62, 1462.e1-7. PMID 24332264 DOI: 10.1016/j.jaci.2013.10.045  1
2014 Walsh JJ, Friedman AK, Sun H, Heller EA, Ku SM, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nature Neuroscience. 17: 27-9. PMID 24270188 DOI: 10.1038/Nn.3591  1
2014 Tucker T, Zahir FR, Griffith M, Delaney A, Chai D, Tsang E, Lemyre E, Dobrzeniecka S, Marra M, Eydoux P, Langlois S, Hamdan FF, Michaud JL, Friedman JM. Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes. European Journal of Human Genetics : Ejhg. 22: 792-800. PMID 24253858 DOI: 10.1038/Ejhg.2013.248  1
2014 Nguyen R, Jett K, Harris GJ, Cai W, Friedman JM, Mautner VF. Benign whole body tumor volume is a risk factor for malignant peripheral nerve sheath tumors in neurofibromatosis type 1. Journal of Neuro-Oncology. 116: 307-13. PMID 24166582 DOI: 10.1007/S11060-013-1293-1  1
2014 Filges I, Nosova E, Bruder E, Tercanli S, Townsend K, Gibson WT, Röthlisberger B, Heinimann K, Hall JG, Gregory-Evans CY, Wasserman WW, Miny P, Friedman JM. Exome sequencing identifies mutations in KIF14 as a novel cause of an autosomal recessive lethal fetal ciliopathy phenotype. Clinical Genetics. 86: 220-8. PMID 24128419 DOI: 10.1111/cge.12301  1
2014 Sanchez DA, Schairer D, Tuckman-Vernon C, Chouake J, Kutner A, Makdisi J, Friedman JM, Nosanchuk JD, Friedman AJ. Amphotericin B releasing nanoparticle topical treatment of Candida spp. in the setting of a burn wound. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 269-77. PMID 23770066 DOI: 10.1016/j.nano.2013.06.002  1
2014 Lohn Z, Adam S, Birch PH, Friedman JM. Incidental findings from clinical genome-wide sequencing: a review. Journal of Genetic Counseling. 23: 463-73. PMID 23709124 DOI: 10.1007/s10897-013-9604-4  1
2014 Knight ZA, Schmidt SF, Birsoy K, Tan K, Friedman JM. Author response: A critical role for mTORC1 in erythropoiesis and anemia Elife. DOI: 10.7554/Elife.01913.013  1
2014 Griffin ER, Perignon MC, Friedman JM, Tucker GE. Effects of woody vegetation on overbank sand transport during a large flood, Rio Puerco, New Mexico Geomorphology. 207: 30-50. DOI: 10.1016/J.Geomorph.2013.10.025  1
2014 Friedman JM, Hanson JW. Clinical Teratology Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.05509-4  1
2014 Friedman JM, Weber-Schöndorfer C. Antineoplastic drugs Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment: Third Edition. 373-399. DOI: 10.1016/B978-0-12-408078-2.00014-7  1
2013 Tucker T, Giroux S, Clément V, Langlois S, Friedman JM, Rousseau F. Prevalence of selected genomic deletions and duplications in a French-Canadian population-based sample of newborns. Molecular Genetics & Genomic Medicine. 1: 87-97. PMID 24498606 DOI: 10.1002/Mgg3.12  1
2013 Domingos AI, Sordillo A, Dietrich MO, Liu ZW, Tellez LA, Vaynshteyn J, Ferreira JG, Ekstrand MI, Horvath TL, de Araujo IE, Friedman JM. Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar. Elife. 2: e01462. PMID 24381247 DOI: 10.7554/Elife.01462  1
2013 Li Z, Ceccarini G, Eisenstein M, Tan K, Friedman JM. Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor. Molecular Metabolism. 2: 364-75. PMID 24327953 DOI: 10.1016/J.Molmet.2013.07.007  1
2013 Kalashikam RR, Battula KK, Kirlampalli V, Friedman JM, Nappanveettil G. Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor. Plos One. 8: e77679. PMID 24204914 DOI: 10.1371/journal.pone.0077679  1
2013 Clemens A, Fraessdorf M, Friedman J. Cardiovascular outcomes during treatment with dabigatran: comprehensive analysis of individual subject data by treatment. Vascular Health and Risk Management. 9: 599-615. PMID 24143109 DOI: 10.2147/VHRM.S49830  1
2013 le Coutre J, Mattson MP, Dillin A, Friedman J, Bistrian B. Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction. The Journal of Nutrition, Health & Aging. 17: 717-20. PMID 24097030 DOI: 10.1007/s12603-013-0375-2  1
2013 Stanley S, Domingos AI, Kelly L, Garfield A, Damanpour S, Heisler L, Friedman J. Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia. Cell Metabolism. 18: 596-607. PMID 24093682 DOI: 10.1016/J.Cmet.2013.09.002  1
2013 Jego S, Glasgow SD, Herrera CG, Ekstrand M, Reed SJ, Boyce R, Friedman J, Burdakov D, Adamantidis AR. Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus. Nature Neuroscience. 16: 1637-43. PMID 24056699 DOI: 10.1038/Nn.3522  1
2013 Roche CJ, Dantsker D, Heller ER, Sabat JE, Friedman JM. Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin. Chemical Physics. 430: 88-97. PMID 24039330 DOI: 10.1016/j.chemphys.2013.04.006  1
2013 Friedman JM. A conversation with NYSDA President Joel M. Friedman, D.D.S. The New York State Dental Journal. 79: 26-8. PMID 24027893  1
2013 Townsend A, Adam S, Birch PH, Friedman JM. Paternalism and the ACMG recommendations on genomic incidental findings: patients seen but not heard. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 751-2. PMID 24008256 DOI: 10.1038/gim.2013.105  1
2013 Thorpe PG, Gilboa SM, Hernandez-Diaz S, Lind J, Cragan JD, Briggs G, Kweder S, Friedman JM, Mitchell AA, Honein MA. Medications in the first trimester of pregnancy: most common exposures and critical gaps in understanding fetal risk. Pharmacoepidemiology and Drug Safety. 22: 1013-8. PMID 23893932 DOI: 10.1002/Pds.3495  1
2013 Roche CJ, Cassera MB, Dantsker D, Hirsch RE, Friedman JM. Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance. The Journal of Biological Chemistry. 288: 22408-25. PMID 23775069 DOI: 10.1074/Jbc.M113.482679  1
2013 Armstrong L, Jett K, Birch P, Kendler DL, McKay H, Tsang E, Stevenson DA, Hanley DA, Egeli D, Burrows M, Friedman JM. The generalized bone phenotype in children with neurofibromatosis 1: a sibling matched case-control study. American Journal of Medical Genetics. Part A. 161: 1654-61. PMID 23713011 DOI: 10.1002/Ajmg.A.36001  1
2013 Friedman JM. A conversation with Jeffrey M. Friedman by Ushma S. Neill. The Journal of Clinical Investigation. 123: 529-30. PMID 23598296 DOI: 10.1172/JCI68394  0.01
2013 Stevenson DA, Little D, Armstrong L, Crawford AH, Eastwood D, Friedman JM, Greggi T, Gutierrez G, Hunter-Schaedle K, Kendler DL, Kolanczyk M, Monsell F, Oetgen M, Richards BS, Schindeler A, et al. Approaches to treating NF1 tibial pseudarthrosis: consensus from the Children's Tumor Foundation NF1 Bone Abnormalities Consortium. Journal of Pediatric Orthopedics. 33: 269-75. PMID 23482262 DOI: 10.1097/Bpo.0B013E31828121B8  1
2013 Dias C, McDonald A, Sincan M, Rupps R, Markello T, Salvarinova R, Santos RF, Menghrajani K, Ahaghotu C, Sutherland DP, Fortuno ES, Kollmann TR, Demos M, Friedman JM, Speert DP, et al. Recurrent subacute post-viral onset of ataxia associated with a PRF1 mutation. European Journal of Human Genetics : Ejhg. 21: 1232-9. PMID 23443029 DOI: 10.1038/Ejhg.2013.20  1
2013 Li Z, Schmidt SF, Friedman JM. Developmental role for endocannabinoid signaling in regulating glucose metabolism and growth. Diabetes. 62: 2359-67. PMID 23423572 DOI: 10.2337/Db12-0901  1
2013 Zhu JL, Hasle H, Correa A, Schendel D, Friedman JM, Olsen J, Rasmussen SA. Hospitalizations among people with Down syndrome: a nationwide population-based study in Denmark. American Journal of Medical Genetics. Part A. 161: 650-7. PMID 23404922 DOI: 10.1002/Ajmg.A.35711  1
2013 Murdock D, Salit J, Stoffel M, Friedman JM, Pe'er I, Breslow JL, Bonnen PE. Longitudinal study shows increasing obesity and hyperglycemia in micronesia. Obesity (Silver Spring, Md.). 21: E421-7. PMID 23404778 DOI: 10.1002/Oby.20041  1
2013 Peters SL, Lind JN, Humphrey JR, Friedman JM, Honein MA, Tassinari MS, Moore CA, Mathis LL, Broussard CS. Safe lists for medications in pregnancy: inadequate evidence base and inconsistent guidance from Web-based information, 2011. Pharmacoepidemiology and Drug Safety. 22: 324-8. PMID 23359404 DOI: 10.1002/pds.3410  1
2013 Nguyen R, Mir TS, Kluwe L, Jett K, Kentsch M, Mueller G, Kehrer-Sawatzki H, Friedman JM, Mautner VF. Cardiac characterization of 16 patients with large NF1 gene deletions. Clinical Genetics. 84: 344-9. PMID 23278345 DOI: 10.1111/cge.12072  1
2013 Cabrales P, Friedman JM. HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species. Antioxidants & Redox Signaling. 18: 2284-97. PMID 23249305 DOI: 10.1089/Ars.2012.5099  1
2013 Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... ... Friedman JM, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/Nature11713  1
2013 Schnabel C, Jett K, Friedman JM, Frieling I, Kruse HP, Mautner V. Effect of vitamin D3 treatment on bone density in neurofibromatosis 1 patients: a retrospective clinical study. Joint, Bone, Spine : Revue Du Rhumatisme. 80: 315-9. PMID 23021159 DOI: 10.1016/j.jbspin.2012.07.010  1
2013 Friedman JM, Hagander L, Hughes CD, Nash KA, Linden AF, Blossom J, Meara JG. Distance to hospital and utilization of surgical services in Haiti: do children, delivering mothers, and patients with emergent surgical conditions experience greater geographical barriers to surgical care? The International Journal of Health Planning and Management. 28: 248-56. PMID 22936638 DOI: 10.1002/hpm.2134  1
2013 Zhu JL, Hasle H, Correa A, Schendel D, Friedman JM, Olsen J, Rasmussen SA. Survival among people with Down syndrome: a nationwide population-based study in Denmark. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 64-9. PMID 22878506 DOI: 10.1038/Gim.2012.93  1
2013 Domingos AI, Sordillo A, Dietrich MO, Liu Z, Tellez LA, Vaynshteyn J, Ferreira JG, Ekstrand MI, Horvath TL, Araujo IEd, Friedman JM. Author response: Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar Elife. DOI: 10.7554/Elife.01462.019  1
2013 Schnabel C, Jett K, Friedman JM, Frieling I, Kruse HP, Mautner V. Effect of vitamin D3 on bone density among patients with a neurofibromatosis type 1: A retrospective clinical study | Effet de la vitamine D3 sur la densité osseuse chez les patients porteurs d'une neurofibromatose 1: Une étude clinique rétrospective Revue Du Rhumatisme (Edition Francaise). 80: 262-266. DOI: 10.1016/j.rhum.2012.09.011  1
2013 Friedman JM, Hanson JW. Clinical Teratology Emery and Rimoin's Principles and Practice of Medical Genetics. 1-39. DOI: 10.1016/B978-0-12-383834-6.00044-6  1
2013 Merigliano MF, Friedman JM, Scott ML. Tree-Ring Records of Variation in Flow and Channel Geometry Treatise On Geomorphology. 12: 145-164. DOI: 10.1016/B978-0-12-374739-6.00319-5  1
2013 Birch P, Friedman JM. Quality of life in NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 93-103. DOI: 10.1007/978-3-642-32864-0_8  1
2013 Stansfield BK, Ingram DA, Conway SJ, Friedman JM. Molecular basis of cardiovascular abnormalities in NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 353-366. DOI: 10.1007/978-3-642-32864-0_23  1
2013 Perignon MC, Tucker GE, Griffin ER, Friedman JM. Effects of riparian vegetation on topographic change during a large flood event, Rio Puerco, New Mexico, USA Journal of Geophysical Research: Earth Surface. 118: 1193-1209. DOI: 10.1002/Jgrf.20073  1
2012 Chouake J, Schairer D, Kutner A, Sanchez DA, Makdisi J, Blecher-Paz K, Nacharaju P, Tuckman-Vernon C, Gialanella P, Friedman JM, Nosanchuk JD, Friedman AJ. Nitrosoglutathione generating nitric oxide nanoparticles as an improved strategy for combating Pseudomonas aeruginosa-infected wounds. Journal of Drugs in Dermatology : Jdd. 11: 1471-7. PMID 23377518  1
2012 Knight ZA, Tan K, Birsoy K, Schmidt S, Garrison JL, Wysocki RW, Emiliano A, Ekstrand MI, Friedman JM. Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell. 151: 1126-37. PMID 23178128 DOI: 10.1016/J.Cell.2012.10.039  1
2012 Nguyen R, Dombi E, Widemann BC, Solomon J, Fuensterer C, Kluwe L, Friedman JM, Mautner VF. Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1. Orphanet Journal of Rare Diseases. 7: 75. PMID 23035791 DOI: 10.1186/1750-1172-7-75  1
2012 Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, et al. Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome. American Journal of Human Genetics. 91: 541-7. PMID 22958903 DOI: 10.1016/J.Ajhg.2012.07.009  1
2012 Friedman J. Leading the charge in leptin research: an interview with Jeffrey Friedman. Disease Models & Mechanisms. 5: 576-9. PMID 22915017 DOI: 10.1242/dmm.010629  1
2012 Tsang E, Rupps R, McGillivray B, Eydoux P, Marra M, Arbour L, Langlois S, Friedman JM, Zahir FR. Life-history chronicle for a patient with the recently described chromosome 4q21 microdeletion syndrome. American Journal of Medical Genetics. Part A. 158: 2606-9. PMID 22903878 DOI: 10.1002/Ajmg.A.35568  1
2012 Townsend A, Adam S, Birch PH, Lohn Z, Rousseau F, Friedman JM. "I want to know what's in Pandora's Box": comparing stakeholder perspectives on incidental findings in clinical whole genomic sequencing. American Journal of Medical Genetics. Part A. 158: 2519-25. PMID 22903777 DOI: 10.1002/ajmg.a.35554  1
2012 Chambers C, Friedman JM. OTIS special issue preface. Birth Defects Research. Part a, Clinical and Molecular Teratology. 94: 569. PMID 22847972 DOI: 10.1002/Bdra.23069  1
2012 Friedman JM. ABCDXXX: The obscenity of postmarketing surveillance for teratogenic effects. Birth Defects Research. Part a, Clinical and Molecular Teratology. 94: 670-6. PMID 22786781 DOI: 10.1002/bdra.23043  1
2012 Nacharaju P, Tuckman-Vernon C, Maier KE, Chouake J, Friedman A, Cabrales P, Friedman JM. A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 27: 150-60. PMID 22705913 DOI: 10.1016/J.Niox.2012.06.003  1
2012 Stanley SA, Gagner JE, Damanpour S, Yoshida M, Dordick JS, Friedman JM. Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science (New York, N.Y.). 336: 604-8. PMID 22556257 DOI: 10.1126/Science.1216753  1
2012 Roche CJ, Dantsker D, Alayash AI, Friedman JM. Enhanced nitrite reductase activity associated with the haptoglobin complexed hemoglobin dimer: functional and antioxidative implications. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 27: 32-9. PMID 22521791 DOI: 10.1016/j.niox.2012.04.002  1
2012 Yang Q, Bailey L, Clarke R, Flanders WD, Liu T, Yesupriya A, Khoury MJ, Friedman JM. Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults. The American Journal of Clinical Nutrition. 95: 1245-53. PMID 22492374 DOI: 10.3945/ajcn.111.022384  1
2012 Demanes DJ, Friedman JM, Park SJ, Steinberg ML, Hayes JK, Kamrava MR. Brachytherapy catheter spacing and stabilization technique. Brachytherapy. 11: 392-7. PMID 22436515 DOI: 10.1016/j.brachy.2012.01.010  1
2012 Blecher K, Martinez LR, Tuckman-Vernon C, Nacharaju P, Schairer D, Chouake J, Friedman JM, Alfieri A, Guha C, Nosanchuk JD, Friedman AJ. Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 1364-71. PMID 22406184 DOI: 10.1016/J.Nano.2012.02.014  1
2012 Han G, Nguyen LN, Macherla C, Chi Y, Friedman JM, Nosanchuk JD, Martinez LR. Nitric oxide-releasing nanoparticles accelerate wound healing by promoting fibroblast migration and collagen deposition. The American Journal of Pathology. 180: 1465-73. PMID 22306734 DOI: 10.1016/J.Ajpath.2011.12.013  1
2012 Schairer D, Martinez LR, Blecher K, Chouake J, Nacharaju P, Gialanella P, Friedman JM, Nosanchuk JD, Friedman A. Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses. Virulence. 3: 62-7. PMID 22286699 DOI: 10.4161/Viru.3.1.18816  1
2012 Bombard Y, Palin J, Friedman JM, Veenstra G, Creighton S, Bottorff JL, Hayden MR. Beyond the patient: the broader impact of genetic discrimination among individuals at risk of Huntington disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 217-26. PMID 22231990 DOI: 10.1002/Ajmg.B.32016  1
2012 Gusev A, Shah MJ, Kenny EE, Ramachandran A, Lowe JK, Salit J, Lee CC, Levandowsky EC, Weaver TN, Doan QC, Peckham HE, McLaughlin SF, Lyons MR, Sheth VN, Stoffel M, ... ... Friedman JM, et al. Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population. Genetics. 190: 679-89. PMID 22135348 DOI: 10.1534/Genetics.111.134874  1
2012 Tsang E, Birch P, Friedman JM. Valuing gene testing in children with possible neurofibromatosis 1. Clinical Genetics. 82: 591-3. PMID 22014292 DOI: 10.1111/j.1399-0004.2011.01801.x  1
2012 Friedman JM. Leptin and the homeostatic system regulating body weight Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-O6  0.01
2012 Jasaitis A, Ouellet H, Lambry JC, Martin JL, Friedman JM, Guertin M, Vos MH. Ultrafast heme-ligand recombination in truncated hemoglobin HbO from Mycobacterium tuberculosis: A ligand cage Chemical Physics. 396: 10-16. DOI: 10.1016/J.Chemphys.2011.04.003  1
2012 Guilbault KR, Brown CS, Friedman JM, Shafroth PB. The influence of chilling requirement on the southern distribution limit of exotic Russian olive (Elaeagnus angustifolia) in western North America Biological Invasions. 14: 1711-1724. DOI: 10.1007/s10530-012-0182-4  1
2011 Friedman JM. Using genomics for birth defects epidemiology: can epigenetics cut the GxE Gordian knot? Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 986-9. PMID 22140073 DOI: 10.1002/bdra.22875  1
2011 Domingos AI, Vaynshteyn J, Voss HU, Ren X, Gradinaru V, Zang F, Deisseroth K, de Araujo IE, Friedman J. Leptin regulates the reward value of nutrient. Nature Neuroscience. 14: 1562-8. PMID 22081158 DOI: 10.1038/nn.2977  1
2011 Birsoy K, Berry R, Wang T, Ceyhan O, Tavazoie S, Friedman JM, Rodeheffer MS. Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development (Cambridge, England). 138: 4709-19. PMID 21989915 DOI: 10.1242/Jcs.101436  1
2011 Friedman AJ, Blecher K, Schairer D, Tuckman-Vernon C, Nacharaju P, Sanchez D, Gialanella P, Martinez LR, Friedman JM, Nosanchuk JD. Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 25: 381-6. PMID 21946032 DOI: 10.1016/J.Niox.2011.09.001  1
2011 Friedman JM, Roelle JE, Cade BS. Genetic and environmental influences on leaf phenology and cold hardiness of native and introduced riparian trees. International Journal of Biometeorology. 55: 775-87. PMID 21927930 DOI: 10.1007/s00484-011-0494-6  1
2011 Ribeiro AC, Ceccarini G, Dupré C, Friedman JM, Pfaff DW, Mark AL. Contrasting effects of leptin on food anticipatory and total locomotor activity. Plos One. 6: e23364. PMID 21853117 DOI: 10.1371/Journal.Pone.0023364  1
2011 Sakakibara K, Saito N, Sato T, Suzuki A, Hasegawa Y, Friedman JM, Kufe DW, Vonhoff DD, Iwami T, Kawabe T. CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity. Blood. 118: 3922-31. PMID 21841164 DOI: 10.1182/blood-2011-01-333138  1
2011 Adam MP, Polifka JE, Friedman JM. Evolving knowledge of the teratogenicity of medications in human pregnancy. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 175-82. PMID 21766440 DOI: 10.1002/ajmg.c.30313  1
2011 Rasmussen SA, Friedman JM. Emerging issues in teratology: an introduction. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 147-9. PMID 21766432 DOI: 10.1002/ajmg.c.30305  1
2011 Friedman JM. How do we know if an exposure is actually teratogenic in humans? American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 170-4. PMID 21766430 DOI: 10.1002/ajmg.c.30302  1
2011 Qiu X, Friedman JM, Liang G. Creating a flexible multiple microRNA expression vector by linking precursor microRNAs. Biochemical and Biophysical Research Communications. 411: 276-80. PMID 21726537 DOI: 10.1016/j.bbrc.2011.06.123  1
2011 Tucker T, Riccardi VM, Brown C, Fee J, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM. S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas. Journal of Neuroscience Research. 89: 1451-60. PMID 21674567 DOI: 10.1002/jnr.22654  1
2011 Gusev A, Kenny EE, Lowe JK, Salit J, Saxena R, Kathiresan S, Altshuler DM, Friedman JM, Breslow JL, Pe'er I. DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. American Journal of Human Genetics. 88: 706-17. PMID 21620352 DOI: 10.1016/J.Ajhg.2011.04.023  1
2011 Friedman JM. Dilate, dilute, constrict, or else in treating hemorrhage? Critical Care Medicine. 39: 1591-2. PMID 21610642 DOI: 10.1097/CCM.0b013e3182185480  1
2011 Moore RA, Warren RL, Freeman JD, Gustavsen JA, Chénard C, Friedman JM, Suttle CA, Zhao Y, Holt RA. The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissue. Plos One. 6: e19838. PMID 21603639 DOI: 10.1371/Journal.Pone.0019838  1
2011 Friedman A, Blecher K, Sanchez D, Tuckman-Vernon C, Gialanella P, Friedman JM, Martinez LR, Nosanchuk JD. Susceptibility of Gram-positive and -negative bacteria to novel nitric oxide-releasing nanoparticle technology. Virulence. 2: 217-21. PMID 21577055 DOI: 10.4161/Viru.2.3.16161  1
2011 Roche CJ, Malashkevich V, Balazs TC, Dantsker D, Chen Q, Moreira J, Almo SC, Friedman JM, Hirsch RE. Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide. The Journal of Biological Chemistry. 286: 23452-66. PMID 21531715 DOI: 10.1074/Jbc.M110.183186  1
2011 Tucker T, Riccardi VM, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM. Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 59: 584-90. PMID 21525187 DOI: 10.1369/0022155411407340  1
2011 Friedman JM. Leptin and the regulation of body weigh. The Keio Journal of Medicine. 60: 1-9. PMID 21460597 DOI: 10.2302/Kjm.60.1  1
2011 Baser ME, Friedman JM, Joe H, Shenton A, Wallace AJ, Ramsden RT, Evans DG. Empirical development of improved diagnostic criteria for neurofibromatosis 2. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 13: 576-81. PMID 21451418 DOI: 10.1097/Gim.0B013E318211Faa9  1
2011 Tucker T, Montpetit A, Chai D, Chan S, Chénier S, Coe BP, Delaney A, Eydoux P, Lam WL, Langlois S, Lemyre E, Marra M, Qian H, Rouleau GA, Vincent D, ... ... Friedman JM, et al. Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardation. Bmc Medical Genomics. 4: 25. PMID 21439053 DOI: 10.1186/1755-8794-4-25  1
2011 Broussard CS, Rasmussen SA, Reefhuis J, Friedman JM, Jann MW, Riehle-Colarusso T, Honein MA. Maternal treatment with opioid analgesics and risk for birth defects. American Journal of Obstetrics and Gynecology. 204: 314.e1-11. PMID 21345403 DOI: 10.1016/j.ajog.2010.12.039  1
2011 Nachuraju P, Friedman AJ, Friedman JM, Cabrales P. Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock. Resuscitation. 82: 607-13. PMID 21342744 DOI: 10.1016/J.Resuscitation.2010.12.025  1
2011 Pérez CA, Stanley SA, Wysocki RW, Havranova J, Ahrens-Nicklas R, Onyimba F, Friedman JM. Molecular annotation of integrative feeding neural circuits. Cell Metabolism. 13: 222-32. PMID 21284989 DOI: 10.1016/J.Cmet.2010.12.013  1
2011 Smith M, Heran MK, Connolly MB, Heran HK, Friedman JM, Jett K, Lyons CJ, Steinbok P, Armstrong L. Cerebrovasculopathy in NF1 associated with ocular and scalp defects. American Journal of Medical Genetics. Part A. 155: 380-5. PMID 21271658 DOI: 10.1002/ajmg.a.33788  1
2011 Bombard Y, Palin J, Friedman JM, Veenstra G, Creighton S, Paulsen JS, Bottorff JL, Hayden MR. Factors associated with experiences of genetic discrimination among individuals at risk for Huntington disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 19-27. PMID 21184581 DOI: 10.1002/Ajmg.B.31130  1
2011 Donato J, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S, Coppari R, Zigman JM, et al. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. The Journal of Clinical Investigation. 121: 355-68. PMID 21183787 DOI: 10.1172/Jci45106  1
2011 Han G, Friedman AJ, Friedman JM. Nitric oxide releasing nanoparticle synthesis and characterization. Methods in Molecular Biology (Clifton, N.J.). 704: 187-95. PMID 21161638 DOI: 10.1007/978-1-61737-964-2_14  1
2011 Kenny EE, Kim M, Gusev A, Lowe JK, Salit J, Smith JG, Kovvali S, Kang HM, Newton-Cheh C, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Eskin E, Breslow JL, et al. Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. Human Molecular Genetics. 20: 827-39. PMID 21118897 DOI: 10.1093/Hmg/Ddq510  1
2011 Cabrales P, Han G, Nacharaju P, Friedman AJ, Friedman JM. Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. American Journal of Physiology. Heart and Circulatory Physiology. 300: H49-56. PMID 21057038 DOI: 10.1152/Ajpheart.00665.2010  1
2011 Alwan S, Reefhuis J, Rasmussen SA, Friedman JM. Patterns of antidepressant medication use among pregnant women in a United States population. Journal of Clinical Pharmacology. 51: 264-70. PMID 20663997 DOI: 10.1177/0091270010373928  1
2011 Broussard CS, Rasmussen SA, Friedman JM. Reply American Journal of Obstetrics and Gynecology. 205: e12. DOI: 10.1016/j.ajog.2011.04.027  1
2010 Friedman JM, Portnof JE. Similar experience. The New York State Dental Journal. 76: 8. PMID 21229665  1
2010 Mihu MR, Sandkovsky U, Han G, Friedman JM, Nosanchuk JD, Martinez LR. The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence. 1: 62-7. PMID 21178416 DOI: 10.4161/Viru.1.2.10038  1
2010 Daston GP, Chapin RE, Scialli AR, Piersma AH, Carney EW, Rogers JM, Friedman JM. A different approach to validating screening assays for developmental toxicity. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 89: 526-30. PMID 21086491 DOI: 10.1002/bdrb.20276  1
2010 Friedman JM. A tale of two hormones. Nature Medicine. 16: 1100-6. PMID 20930753 DOI: 10.1038/Nm1010-1100  1
2010 Israel HA, Behrman DA, Friedman JM, Silberstein J. Rationale for early versus late intervention with arthroscopy for treatment of inflammatory/degenerative temporomandibular joint disorders. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. 68: 2661-7. PMID 20739111 DOI: 10.1016/j.joms.2010.05.051  1
2010 Friedman JM. The principles of teratology: are they still true? Birth Defects Research. Part a, Clinical and Molecular Teratology. 88: 766-8. PMID 20706993 DOI: 10.1002/bdra.20697  0.01
2010 Knight ZA, Hannan KS, Greenberg ML, Friedman JM. Hyperleptinemia is required for the development of leptin resistance. Plos One. 5: e11376. PMID 20613882 DOI: 10.1371/Journal.Pone.0011376  1
2010 Miller DT, Adam MP, Aradhya S, Biesecker LG, Brothman AR, Carter NP, Church DM, Crolla JA, Eichler EE, Epstein CJ, Faucett WA, Feuk L, Friedman JM, Hamosh A, Jackson L, et al. Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies. American Journal of Human Genetics. 86: 749-64. PMID 20466091 DOI: 10.1016/J.Ajhg.2010.04.006  1
2010 Cabrales P, Han G, Roche C, Nacharaju P, Friedman AJ, Friedman JM. Sustained release nitric oxide from long-lived circulating nanoparticles. Free Radical Biology & Medicine. 49: 530-8. PMID 20460149 DOI: 10.1016/J.Freeradbiomed.2010.04.034  1
2010 Alwan S, Reefhuis J, Botto LD, Rasmussen SA, Correa A, Friedman JM. Maternal use of bupropion and risk for congenital heart defects. American Journal of Obstetrics and Gynecology. 203: 52.e1-6. PMID 20417496 DOI: 10.1016/j.ajog.2010.02.015  1
2010 Regier DA, Friedman JM, Marra CA. Value for money? Array genomic hybridization for diagnostic testing for genetic causes of intellectual disability. American Journal of Human Genetics. 86: 765-72. PMID 20398885 DOI: 10.1016/J.Ajhg.2010.03.009  1
2010 Stanley S, Pinto S, Segal J, Pérez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM. Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically. Proceedings of the National Academy of Sciences of the United States of America. 107: 7024-9. PMID 20351287 DOI: 10.1073/Pnas.1002790107  1
2010 Martinez LR, Mihu MR, Tar M, Cordero RJ, Han G, Friedman AJ, Friedman JM, Nosanchuk JD. Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. The Journal of Infectious Diseases. 201: 1436-40. PMID 20331379 DOI: 10.1086/651558  1
2010 Navati MS, Friedman JM. Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide. The Journal of Physical Chemistry. B. 114: 2938-43. PMID 20146537 DOI: 10.1021/jp909425z  1
2010 Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. Antidiabetic effects of IGFBP2, a leptin-regulated gene. Cell Metabolism. 11: 11-22. PMID 20074524 DOI: 10.1016/J.Cmet.2009.11.007  1
2010 Tsang ES, Birch P, Friedman JM, Johnston D, Tucker T, Armstrong L. Prevalence of dental caries in children with neurofibromatosis 1. Clinical Oral Investigations. 14: 479-80; author reply. PMID 20049496 DOI: 10.1007/s00784-009-0361-6  1
2010 Jett K, Friedman JM. Clinical and genetic aspects of neurofibromatosis 1. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 12: 1-11. PMID 20027112 DOI: 10.1097/GIM.0b013e3181bf15e3  1
2010 Roche CJ, Friedman JM. NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 22: 180-90. PMID 19919854 DOI: 10.1016/j.niox.2009.11.003  1
2010 Gautron L, Lee C, Funahashi H, Friedman J, Lee S, Elmquist J. Melanocortin-4 receptor expression in a vago-vagal circuitry involved in postprandial functions. The Journal of Comparative Neurology. 518: 6-24. PMID 19882715 DOI: 10.1002/Cne.22221  1
2010 Bonnen PE, Lowe JK, Altshuler DM, Breslow JL, Stoffel M, Friedman JM, Pe'er I. European admixture on the Micronesian island of Kosrae: lessons from complete genetic information. European Journal of Human Genetics : Ejhg. 18: 309-16. PMID 19844264 DOI: 10.1038/Ejhg.2009.180  1
2010 Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone JM, Fong CT, Kussmann JL, Grange DK, Gorski JL, Zahir F, Yong SL, Morris MM, ... ... Friedman JM, et al. Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome. Journal of Medical Genetics. 47: 155-61. PMID 19833603 DOI: 10.1136/Jmg.2009.070573  1
2010 Martinez LR, Mihu MR, Han G, Frases S, Cordero RJ, Casadevall A, Friedman AJ, Friedman JM, Nosanchuk JD. The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials. 31: 669-79. PMID 19819009 DOI: 10.1016/J.Biomaterials.2009.09.087  1
2010 Moslehi R, Singh R, Lessner L, Friedman JM. Impact of BRCA mutations on female fertility and offspring sex ratio. American Journal of Human Biology : the Official Journal of the Human Biology Council. 22: 201-5. PMID 19642207 DOI: 10.1002/ajhb.20978  0.04
2010 Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene (DOI:10.1016/j.cmet.2009.11.007) Cell Metabolism. 11: 239. DOI: 10.1016/J.Cmet.2010.02.010  1
2009 Guo F, Friedman JM. Osmolyte-induced perturbations of hydrogen bonding between hydration layer waters: correlation with protein conformational changes. The Journal of Physical Chemistry. B. 113: 16632-42. PMID 19961206 DOI: 10.1021/jp9072284  1
2009 Han G, Martinez LR, Mihu MR, Friedman AJ, Friedman JM, Nosanchuk JD. Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection. Plos One. 4: e7804. PMID 19915659 DOI: 10.1371/Journal.Pone.0007804  1
2009 Shum JW, Lee AW, Lustman K, Friedman JM. Cavernous sinus thrombosis secondary to fracture of posterior maxillary sinus wall. Case report. The New York State Dental Journal. 75: 41-4. PMID 19882841  0.04
2009 Alon T, Zhou L, Pérez CA, Garfield AS, Friedman JM, Heisler LK. Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. Endocrinology. 150: 5626-32. PMID 19854866 DOI: 10.1210/En.2009-0881  1
2009 Makela NL, Birch PH, Friedman JM, Marra CA. Parental perceived value of a diagnosis for intellectual disability (ID): a qualitative comparison of families with and without a diagnosis for their child's ID. American Journal of Medical Genetics. Part A. 149: 2393-402. PMID 19842198 DOI: 10.1002/Ajmg.A.33050  1
2009 Lehman AM, Friedman JM, Chai D, Zahir FR, Marra MA, Prisman L, Tsang E, Eydoux P, Armstrong L. A characteristic syndrome associated with microduplication of 8q12, inclusive of CHD7. European Journal of Medical Genetics. 52: 436-9. PMID 19772954 DOI: 10.1016/J.Ejmg.2009.09.006  1
2009 Elefteriou F, Kolanczyk M, Schindeler A, Viskochil DH, Hock JM, Schorry EK, Crawford AH, Friedman JM, Little D, Peltonen J, Carey JC, Feldman D, Yu X, Armstrong L, Birch P, et al. Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options. American Journal of Medical Genetics. Part A. 149: 2327-38. PMID 19764036 DOI: 10.1002/Ajmg.A.33045  1
2009 Portnof JE, Friedman JM, Reich R, Freedman PD, Behrman DA. Oral ectomesenchymal chondromyxoid tumor: case report and literature review. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 108: e20-4. PMID 19716722 DOI: 10.1016/j.tripleo.2009.05.040  1
2009 Friedman JM, Jones PA. MicroRNAs: critical mediators of differentiation, development and disease. Swiss Medical Weekly. 139: 466-72. PMID 19705306 DOI: 10.4414/Smw.2009.12794  1
2009 Tucker T, Marra M, Friedman JM. Massively parallel sequencing: the next big thing in genetic medicine. American Journal of Human Genetics. 85: 142-54. PMID 19679224 DOI: 10.1016/J.Ajhg.2009.06.022  1
2009 Kenny EE, Gusev A, Riegel K, Lütjohann D, Lowe JK, Salit J, Maller JB, Stoffel M, Daly MJ, Altshuler DM, Friedman JM, Breslow JL, Pe'er I, Sehayek E. Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae. Proceedings of the National Academy of Sciences of the United States of America. 106: 13886-91. PMID 19667188 DOI: 10.1073/Pnas.0907336106  1
2009 Navati MS, Friedman JM. Reactivity of glass-embedded met hemoglobin derivatives toward external NO: implications for nitrite-mediated production of bioactive NO. Journal of the American Chemical Society. 131: 12273-9. PMID 19663497 DOI: 10.1021/ja903364h  1
2009 Ceccarini G, Flavell RR, Butelman ER, Synan M, Willnow TE, Bar-Dagan M, Goldsmith SJ, Kreek MJ, Kothari P, Vallabhajosula S, Muir TW, Friedman JM. PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metabolism. 10: 148-59. PMID 19656493 DOI: 10.1016/J.Cmet.2009.07.001  1
2009 Friedman JM, Jones PA, Liang G. The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer. Cell Cycle (Georgetown, Tex.). 8: 2313-4. PMID 19625769 DOI: 10.4161/Cc.8.15.9168  1
2009 Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G, Schmidt S, Vidal-Puig A, Diano S, Andrews P, Brand MD, Friedman J. Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. Proceedings of the National Academy of Sciences of the United States of America. 106: 13100-5. PMID 19622746 DOI: 10.1073/Pnas.0903723106  1
2009 Guo F, Friedman JM. Charge density-dependent modifications of hydration shell waters by Hofmeister ions. Journal of the American Chemical Society. 131: 11010-8. PMID 19603752 DOI: 10.1021/ja902240j  1
2009 Friedman JM. Big risks in small groups: The difference between epidemiology and counselling. Birth Defects Research. Part a, Clinical and Molecular Teratology. 85: 720-4. PMID 19572407 DOI: 10.1002/bdra.20606  0.01
2009 Vincent KR, Friedman JM, Griffin ER. Erosional consequence of saltcedar control. Environmental Management. 44: 218-27. PMID 19548024 DOI: 10.1007/s00267-009-9314-8  1
2009 Bombard Y, Veenstra G, Friedman JM, Creighton S, Currie L, Paulsen JS, Bottorff JL, Hayden MR. Perceptions of genetic discrimination among people at risk for Huntington's disease: a cross sectional survey. Bmj (Clinical Research Ed.). 338: b2175. PMID 19509425 DOI: 10.1136/Bmj.B2175  1
2009 Regier DA, Friedman JM, Makela N, Ryan M, Marra CA. Valuing the benefit of diagnostic testing for genetic causes of idiopathic developmental disability: willingness to pay from families of affected children. Clinical Genetics. 75: 514-21. PMID 19508416 DOI: 10.1111/J.1399-0004.2009.01193.X  1
2009 Alwan S, Friedman JM. Safety of selective serotonin reuptake inhibitors in pregnancy. Cns Drugs. 23: 493-509. PMID 19480468 DOI: 10.2165/00023210-200923060-00004  1
2009 Wang W, Huang L, Huang Y, Yin JW, Berk AJ, Friedman JM, Wang G. Mediator MED23 links insulin signaling to the adipogenesis transcription cascade. Developmental Cell. 16: 764-71. PMID 19460352 DOI: 10.1016/J.Devcel.2009.04.006  1
2009 Friedman JM. Obesity: Causes and control of excess body fat. Nature. 459: 340-2. PMID 19458707 DOI: 10.1038/459340A  1
2009 Zahir FR, Langlois S, Gall K, Eydoux P, Marra MA, Friedman JM. A novel de novo 1.1 Mb duplication of 17q21.33 associated with cognitive impairment and other anomalies. American Journal of Medical Genetics. Part A. 149: 1257-62. PMID 19449402 DOI: 10.1002/Ajmg.A.32827  1
2009 Yang Q, Bostick RM, Friedman JM, Flanders WD. Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1439-47. PMID 19423522 DOI: 10.1158/1055-9965.Epi-08-0908  1
2009 Smith JG, Lowe JK, Kovvali S, Maller JB, Salit J, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Breslow JL, Newton-Cheh C. Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 634-41. PMID 19389651 DOI: 10.1016/J.Hrthm.2009.02.022  1
2009 Martinez LR, Han G, Chacko M, Mihu MR, Jacobson M, Gialanella P, Friedman AJ, Nosanchuk JD, Friedman JM. Antimicrobial and healing efficacy of sustained release nitric oxide nanoparticles against Staphylococcus aureus skin infection. The Journal of Investigative Dermatology. 129: 2463-9. PMID 19387479 DOI: 10.1038/Jid.2009.95  1
2009 Scott MM, Lachey JL, Sternson SM, Lee CE, Elias CF, Friedman JM, Elmquist JK. Leptin targets in the mouse brain. The Journal of Comparative Neurology. 514: 518-32. PMID 19350671 DOI: 10.1002/Cne.22025  1
2009 Giordano D, Boechi L, Vergara A, Martí MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, di Prisco G, Verde C. The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species--oxygen-binding equilibria, kinetics and molecular dynamics. The Febs Journal. 276: 2266-77. PMID 19292863 DOI: 10.1111/J.1742-4658.2009.06954.X  1
2009 Friedman JM, Liang G, Liu CC, Wolff EM, Tsai YC, Ye W, Zhou X, Jones PA. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Research. 69: 2623-9. PMID 19258506 DOI: 10.1158/0008-5472.CAN-08-3114  1
2009 Lowe JK, Maller JB, Pe'er I, Neale BM, Salit J, Kenny EE, Shea JL, Burkhardt R, Smith JG, Ji W, Noel M, Foo JN, Blundell ML, Skilling V, Garcia L, ... ... Friedman JM, et al. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. Plos Genetics. 5: e1000365. PMID 19197348 DOI: 10.1371/Journal.Pgen.1000365  1
2009 Friedman JM. Leptin at 14 y of age: an ongoing story. The American Journal of Clinical Nutrition. 89: 973S-979S. PMID 19190071 DOI: 10.3945/Ajcn.2008.26788B  1
2009 Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G. Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. Biochemical and Biophysical Research Communications. 379: 726-31. PMID 19116145 DOI: 10.1016/J.Bbrc.2008.12.098  1
2009 Tucker T, Schnabel C, Hartmann M, Friedrich RE, Frieling I, Kruse HP, Mautner VF, Friedman JM. Bone health and fracture rate in individuals with neurofibromatosis 1 (NF1). Journal of Medical Genetics. 46: 259-65. PMID 19066167 DOI: 10.1136/jmg.2008.061895  1
2009 Friedman JM. High-resolution array genomic hybridization in prenatal diagnosis. Prenatal Diagnosis. 29: 20-8. PMID 19009552 DOI: 10.1002/pd.2129  0.01
2009 Gusev A, Lowe JK, Stoffel M, Daly MJ, Altshuler D, Breslow JL, Friedman JM, Pe'er I. Whole population, genome-wide mapping of hidden relatedness. Genome Research. 19: 318-26. PMID 18971310 DOI: 10.1101/Gr.081398.108  1
2009 Tucker T, Friedman JM, Friedrich RE, Wenzel R, Fünsterer C, Mautner VF. Longitudinal study of neurofibromatosis 1 associated plexiform neurofibromas. Journal of Medical Genetics. 46: 81-5. PMID 18930997 DOI: 10.1136/jmg.2008.061051  1
2008 Friedman JM, Roelle JE, Gaskin JF, Pepper AE, Manhart JR. Latitudinal variation in cold hardiness in introduced Tamarix and native Populus. Evolutionary Applications. 1: 598-607. PMID 25567800 DOI: 10.1111/J.1752-4571.2008.00044.X  1
2008 Delaney AD, Qian H, Friedman JM, Marra MA. Use of Affymetrix mapping arrays in the diagnosis of gene copy number variation. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 8.13. PMID 18972373 DOI: 10.1002/0471142905.Hg0813S59  1
2008 Rodeheffer MS, Birsoy K, Friedman JM. Identification of white adipocyte progenitor cells in vivo. Cell. 135: 240-9. PMID 18835024 DOI: 10.1016/J.Cell.2008.09.036  1
2008 Burkhardt R, Kenny EE, Lowe JK, Birkeland A, Josowitz R, Noel M, Salit J, Maller JB, Pe'er I, Daly MJ, Altshuler D, Stoffel M, Friedman JM, Breslow JL. Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2078-84. PMID 18802019 DOI: 10.1161/Atvbaha.108.172288  1
2008 Birsoy K, Soukas A, Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva G, Viale A, Socci ND, Friedman JM. Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12985-90. PMID 18753616 DOI: 10.1073/Pnas.0805621105  1
2008 Ouellet YH, Daigle R, Lagüe P, Dantsker D, Milani M, Bolognesi M, Friedman JM, Guertin M. Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water. The Journal of Biological Chemistry. 283: 27270-8. PMID 18676995 DOI: 10.1074/Jbc.M804215200  1
2008 Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 454: 846-51. PMID 18668043 DOI: 10.1038/Nature07181  1
2008 Yang QH, Botto LD, Gallagher M, Friedman JM, Sanders CL, Koontz D, Nikolova S, Erickson JD, Steinberg K. Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank. The American Journal of Clinical Nutrition. 88: 232-46. PMID 18614746  1
2008 Flavell RR, Kothari P, Bar-Dagan M, Synan M, Vallabhajosula S, Friedman JM, Muir TW, Ceccarini G. Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. Journal of the American Chemical Society. 130: 9106-12. PMID 18570424 DOI: 10.1021/Ja801666Z  1
2008 Mautner VF, Asuagbor FA, Dombi E, Fünsterer C, Kluwe L, Wenzel R, Widemann BC, Friedman JM. Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1. Neuro-Oncology. 10: 593-8. PMID 18559970 DOI: 10.1215/15228517-2008-011  1
2008 Zeigerer A, Rodeheffer MS, McGraw TE, Friedman JM. Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism. Experimental Cell Research. 314: 2249-56. PMID 18501893 DOI: 10.1016/J.Yexcr.2008.04.003  1
2008 Vincent JB, Choufani S, Horike S, Stachowiak B, Li M, Dill FJ, Marshall C, Hrynchak M, Pewsey E, Ukadike KC, Friedman JM, Srivastava AK, Scherer SW. A translocation t(6;7)(p11-p12;q22) associated with autism and mental retardation: localization and identification of candidate genes at the breakpoints. Psychiatric Genetics. 18: 101-9. PMID 18496206 DOI: 10.1097/Ypg.0B013E3282F97Df7  0.04
2008 Friedman AJ, Han G, Navati MS, Chacko M, Gunther L, Alfieri A, Friedman JM. Sustained release nitric oxide releasing nanoparticles: characterization of a novel delivery platform based on nitrite containing hydrogel/glass composites. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 12-20. PMID 18457680 DOI: 10.1016/j.niox.2008.04.003  1
2008 Birsoy K, Chen Z, Friedman J. Transcriptional regulation of adipogenesis by KLF4. Cell Metabolism. 7: 339-47. PMID 18396140 DOI: 10.1016/J.Cmet.2008.02.001  1
2008 Shifera AS, Friedman JM, Horwitz MS. IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways. Molecular and Cellular Biochemistry. 310: 181-90. PMID 18080803 DOI: 10.1007/S11010-007-9679-Z  1
2008 Chambers CD, Polifka JE, Friedman JM. Drug safety in pregnant women and their babies: ignorance not bliss. Clinical Pharmacology and Therapeutics. 83: 181-3. PMID 18073777 DOI: 10.1038/sj.clpt.6100448  1
2008 Zahir FR, Baross A, Delaney AD, Eydoux P, Fernandes ND, Pugh T, Marra MA, Friedman JM. A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1alpha. Journal of Medical Genetics. 45: 239-43. PMID 18057082 DOI: 10.1136/Jmg.2007.054437  1
2007 Tucker T, Birch P, Savoy DM, Friedman JM. Increased dental caries in people with neurofibromatosis 1. Clinical Genetics. 72: 524-7. PMID 18001351 DOI: 10.1111/j.1399-0004.2007.00886.x  1
2007 Baross A, Delaney AD, Li HI, Nayar T, Flibotte S, Qian H, Chan SY, Asano J, Ally A, Cao M, Birch P, Brown-John M, Fernandes N, Go A, Kennedy G, ... ... Friedman JM, et al. Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data. Bmc Bioinformatics. 8: 368. PMID 17910767 DOI: 10.1186/1471-2105-8-368  1
2007 Samuni U, Roche CJ, Dantsker D, Friedman JM. Conformational dependence of hemoglobin reactivity under high viscosity conditions: the role of solvent slaved dynamics. Journal of the American Chemical Society. 129: 12756-64. PMID 17910446 DOI: 10.1021/Ja072342B  1
2007 Zahir F, Friedman JM. The impact of array genomic hybridization on mental retardation research: a review of current technologies and their clinical utility. Clinical Genetics. 72: 271-87. PMID 17850622 DOI: 10.1111/j.1399-0004.2007.00847.x  0.01
2007 Lammert M, Friedrich RE, Friedman JM, Mautner VF, Tucker T. Early primary tooth eruption in neurofibromatosis 1 individuals. European Journal of Oral Sciences. 115: 425-6. PMID 17850432 DOI: 10.1111/j.1600-0722.2007.00474.x  1
2007 Stevenson DA, Viskochil DH, Schorry EK, Crawford AH, D'Astous J, Murray KA, Friedman JM, Armstrong L, Carey JC. The use of anterolateral bowing of the lower leg in the diagnostic criteria for neurofibromatosis type 1. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 9: 409-12. PMID 17666887 DOI: 10.1097/GIM.0b013e3180986e05  1
2007 Alwan S, Reefhuis J, Rasmussen SA, Olney RS, Friedman JM. Use of selective serotonin-reuptake inhibitors in pregnancy and the risk of birth defects. The New England Journal of Medicine. 356: 2684-92. PMID 17596602 DOI: 10.1056/NEJMoa066584  1
2007 Samuni U, Dantsker D, Roche CJ, Friedman JM. Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene. 398: 234-48. PMID 17570619 DOI: 10.1016/J.Gene.2007.04.032  1
2007 Zahir F, Firth HV, Baross A, Delaney AD, Eydoux P, Gibson WT, Langlois S, Martin H, Willatt L, Marra MA, Friedman JM. Novel deletions of 14q11.2 associated with developmental delay, cognitive impairment and similar minor anomalies in three children. Journal of Medical Genetics. 44: 556-61. PMID 17545556 DOI: 10.1136/Jmg.2007.050823  1
2007 Alwan S, Armstrong L, Joe H, Birch PH, Szudek J, Friedman JM. Associations of osseous abnormalities in Neurofibromatosis 1. American Journal of Medical Genetics. Part A. 143: 1326-33. PMID 17506102 DOI: 10.1002/Ajmg.A.31754  1
2007 Yang QH, Carter HK, Mulinare J, Berry RJ, Friedman JM, Erickson JD. Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001-2002. The American Journal of Clinical Nutrition. 85: 1409-16. PMID 17490980  1
2007 Weksberg R, Shuman C, Wilkins-Haug L, Mann M, Croughan M, Stewart D, Rakowsky C, Leader A, Hall J, Friedman JM, Simpson JL, Holmes L, Infante-Rivard C. Workshop report: evaluation of genetic and epigenetic risks associated with assisted reproductive technologies and infertility. Fertility and Sterility. 88: 27-31. PMID 17442312 DOI: 10.1016/J.Fertnstert.2006.11.114  1
2007 Nacharaju P, Friedman JM, Prabhakaran M, Acharya SA, Manjula BN. Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin. Biochemistry. 46: 4554-64. PMID 17381072 DOI: 10.1021/bi0621462  1
2007 Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM. Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. Cell Metabolism. 5: 115-28. PMID 17276354 DOI: 10.1016/J.Cmet.2007.01.005  1
2007 Sha SK, Sato T, Kobayashi H, Ishigaki M, Yamamoto S, Sato H, Takada A, Nakajyo S, Mochizuki Y, Friedman JM, Cheng FC, Okura T, Kimura R, Kufe DW, Vonhoff DD, et al. Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint. Molecular Cancer Therapeutics. 6: 147-53. PMID 17237275 DOI: 10.1158/1535-7163.MCT-06-0371  1
2007 Menten B, Buysse K, Zahir F, Hellemans J, Hamilton SJ, Costa T, Fagerstrom C, Anadiotis G, Kingsbury D, McGillivray BC, Marra MA, Friedman JM, Speleman F, Mortier G. Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14. Journal of Medical Genetics. 44: 264-8. PMID 17220210 DOI: 10.1136/Jmg.2006.047860  1
2007 Robinson WP, McGillivray B, Friedman JM. Pregnancy and postnatal outcome of mosaic isochromosome 20q. Prenatal Diagnosis. 27: 143-5. PMID 17191261 DOI: 10.1002/pd.1636  1
2007 Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metabolism. 5: 21-33. PMID 17189204 DOI: 10.1016/J.Cmet.2006.12.002  1
2006 Roche CJ, Guo F, Friedman JM. Molecular level probing of preferential hydration and its modulation by osmolytes through the use of pyranine complexed to hemoglobin. The Journal of Biological Chemistry. 281: 38757-68. PMID 17057250 DOI: 10.1074/jbc.M608835200  1
2006 Kenneson A, Kolor K, Yang Q, Olney RS, Rasmussen SA, Friedman JM. Trends and racial disparities in muscular dystrophy deaths in the United States, 1983-1998: an analysis of multiple cause mortality data. American Journal of Medical Genetics. Part A. 140: 2289-97. PMID 17022078 DOI: 10.1002/ajmg.a.31437  1
2006 Navati MS, Friedman JM. Sugar-derived glasses support thermal and photo-initiated electron transfer processes over macroscopic distances. The Journal of Biological Chemistry. 281: 36021-8. PMID 17005567 DOI: 10.1074/jbc.M606866200  1
2006 Roche CJ, Dantsker D, Samuni U, Friedman JM. Nitrite reductase activity of sol-gel-encapsulated deoxyhemoglobin. Influence of quaternary and tertiary structure. The Journal of Biological Chemistry. 281: 36874-82. PMID 16984908 DOI: 10.1074/Jbc.M603914200  1
2006 Friedman JM, Baross A, Delaney AD, Ally A, Arbour L, Armstrong L, Asano J, Bailey DK, Barber S, Birch P, Brown-John M, Cao M, Chan S, Charest DL, Farnoud N, et al. Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation. American Journal of Human Genetics. 79: 500-13. PMID 16909388 DOI: 10.1086/507471  1
2006 Cragan JD, Friedman JM, Holmes LB, Uhl K, Green NS, Riley L. Ensuring the safe and effective use of medications during pregnancy: planning and prevention through preconception care. Maternal and Child Health Journal. 10: S129-35. PMID 16850277 DOI: 10.1007/s10995-006-0102-2  1
2006 Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, ... ... Friedman JM, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 51: 239-49. PMID 16846858 DOI: 10.1016/J.Neuron.2006.06.004  1
2006 Rasmussen SA, Wong LY, Correa A, Gambrell D, Friedman JM. Survival in infants with Down syndrome, Metropolitan Atlanta, 1979-1998. The Journal of Pediatrics. 148: 806-812. PMID 16769392 DOI: 10.1016/j.jpeds.2006.01.010  1
2006 Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell. 9: 435-43. PMID 16766263 DOI: 10.1016/J.Ccr.2006.04.020  1
2006 Friedman JM. ACE inhibitors and congenital anomalies. The New England Journal of Medicine. 354: 2498-500. PMID 16760451 DOI: 10.1056/NEJMe068089  0.01
2006 Reefhuis J, Rasmussen SA, Friedman JM. Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn. The New England Journal of Medicine. 354: 2188-90; author repl. PMID 16707761 DOI: 10.1056/NEJMc060602  1
2006 Lammert M, Friedman JM, Roth HJ, Friedrich RE, Kluwe L, Atkins D, Schooler T, Mautner VF. Vitamin D deficiency associated with number of neurofibromas in neurofibromatosis 1. Journal of Medical Genetics. 43: 810-3. PMID 16571643 DOI: 10.1136/jmg.2006.041095  1
2006 Shmulewitz D, Heath SC, Blundell ML, Han Z, Sharma R, Salit J, Auerbach SB, Signorini S, Breslow JL, Stoffel M, Friedman JM. Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. Proceedings of the National Academy of Sciences of the United States of America. 103: 3502-9. PMID 16537441 DOI: 10.1073/Pnas.0510156103  1
2006 Baser ME, Friedman JM, Evans DG. Increasing the specificity of diagnostic criteria for schwannomatosis. Neurology. 66: 730-2. PMID 16534111 DOI: 10.1212/01.wnl.0000201190.89751.41  1
2006 Yang Q, Botto LD, Erickson JD, Berry RJ, Sambell C, Johansen H, Friedman JM. Improvement in stroke mortality in Canada and the United States, 1990 to 2002. Circulation. 113: 1335-43. PMID 16534029 DOI: 10.1161/CIRCULATIONAHA.105.570846  1
2006 Samuni U, Roche CJ, Dantsker D, Juszczak LJ, Friedman JM. Modulation of reactivity and conformation within the T-quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation. Biochemistry. 45: 2820-35. PMID 16503637 DOI: 10.1021/Bi050010I  1
2006 Das TK, Dewilde S, Friedman JM, Moens L, Rousseau DL. Multiple active site conformers in the carbon monoxide complexes of trematode hemoglobins. The Journal of Biological Chemistry. 281: 11471-9. PMID 16481317 DOI: 10.1074/Jbc.M512054200  1
2006 Maliga Z, Xing J, Cheung H, Juszczak LJ, Friedman JM, Rosenfeld SS. A pathway of structural changes produced by monastrol binding to Eg5. The Journal of Biological Chemistry. 281: 7977-82. PMID 16434397 DOI: 10.1074/Jbc.M511955200  1
2006 Bonnen PE, Pe'er I, Plenge RM, Salit J, Lowe JK, Shapero MH, Lifton RP, Breslow JL, Daly MJ, Reich DE, Jones KW, Stoffel M, Altshuler D, Friedman JM. Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia. Nature Genetics. 38: 214-7. PMID 16429162 DOI: 10.1038/Ng1712  1
2006 Alon T, Friedman JM. Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 389-97. PMID 16407534 DOI: 10.1523/Jneurosci.1203-05.2006  1
2006 Yang Q, Khoury MJ, Friedman JM, Little J, Flanders WD. Authors' response to a refinement to 'how many genes underlie the occurrence of common complex diseases in the population?' by Ramal Moonesinghe [9] International Journal of Epidemiology. 35: 498. DOI: 10.1093/ije/dyi289  1
2005 Tyson C, Harvard C, Locker R, Friedman JM, Langlois S, Lewis ME, Van Allen M, Somerville M, Arbour L, Clarke L, McGilivray B, Yong SL, Siegel-Bartel J, Rajcan-Separovic E. Submicroscopic deletions and duplications in individuals with intellectual disability detected by array-CGH. American Journal of Medical Genetics. Part A. 139: 173-85. PMID 16283669 DOI: 10.1002/Ajmg.A.31015  1
2005 Alwan S, Polifka JE, Friedman JM. Addendum: sartan treatment during pregnancy. Birth Defects Research. Part a, Clinical and Molecular Teratology. 73: 904-5. PMID 16206284 DOI: 10.1002/bdra.20194  1
2005 Sternson SM, Shepherd GM, Friedman JM. Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nature Neuroscience. 8: 1356-63. PMID 16172601 DOI: 10.1038/Nn1550  1
2005 Dantsker D, Roche C, Samuni U, Blouin G, Olson JS, Friedman JM. The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities. The Journal of Biological Chemistry. 280: 38740-55. PMID 16155005 DOI: 10.1074/Jbc.M506333200  1
2005 Acharya SA, Friedman JM, Manjula BN, Intaglietta M, Tsai AG, Winslow RM, Malavalli A, Vandegriff K, Smith PK. Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33: 239-55. PMID 16152690 DOI: 10.1081/Bio-200066365  1
2005 Manjula BN, Tsai AG, Intaglietta M, Tsai CH, Ho C, Smith PK, Perumalsamy K, Kanika ND, Friedman JM, Acharya SA. Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. The Protein Journal. 24: 133-46. PMID 16096719 DOI: 10.1007/S10930-005-7837-2  1
2005 Lee TK, Friedman JM. Analysis of NF1 transcriptional regulatory elements. American Journal of Medical Genetics. Part A. 137: 130-5. PMID 16059932 DOI: 10.1002/ajmg.a.30699  0.32
2005 Chen Z, Torrens JI, Anand A, Spiegelman BM, Friedman JM. Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metabolism. 1: 93-106. PMID 16054051 DOI: 10.1016/J.Cmet.2004.12.009  1
2005 Tucker T, Wolkenstein P, Revuz J, Zeller J, Friedman JM. Association between benign and malignant peripheral nerve sheath tumors in NF1. Neurology. 65: 205-11. PMID 16043787 DOI: 10.1212/01.wnl.0000168830.79997.13  1
2005 Baser ME, Kuramoto L, Woods R, Joe H, Friedman JM, Wallace AJ, Ramsden RT, Olschwang S, Bijlsma E, Kalamarides M, Papi L, Kato R, Carroll J, Lázaro C, Joncourt F, et al. The location of constitutional neurofibromatosis 2 (NF2) splice site mutations is associated with the severity of NF2. Journal of Medical Genetics. 42: 540-6. PMID 15994874 DOI: 10.1136/Jmg.2004.029504  1
2005 Lammert M, Kappler M, Mautner VF, Lammert K, Störkel S, Friedman JM, Atkins D. Decreased bone mineral density in patients with neurofibromatosis 1. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 16: 1161-6. PMID 15988556 DOI: 10.1007/s00198-005-1940-2  1
2005 MacCollin M, Chiocca EA, Evans DG, Friedman JM, Horvitz R, Jaramillo D, Lev M, Mautner VF, Niimura M, Plotkin SR, Sang CN, Stemmer-Rachamimov A, Roach ES. Diagnostic criteria for schwannomatosis. Neurology. 64: 1838-45. PMID 15955931 DOI: 10.1212/01.Wnl.0000163982.78900.Ad  1
2005 Samuni U, Friedman JM. Proteins in motion: resonance Raman spectroscopy as a probe of functional intermediates. Methods in Molecular Biology (Clifton, N.J.). 305: 287-300. PMID 15940003 DOI: 10.1385/1-59259-912-5:287  1
2005 Li D, Yea S, Li S, Chen Z, Narla G, Banck M, Laborda J, Tan S, Friedman JM, Friedman SL, Walsh MJ. Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. The Journal of Biological Chemistry. 280: 26941-52. PMID 15917248 DOI: 10.1074/Jbc.M500463200  1
2005 Dantsker D, Samuni U, Friedman JM, Agmon N. A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model. Biochimica Et Biophysica Acta. 1749: 234-51. PMID 15914102 DOI: 10.1016/J.Bbapap.2005.04.002  1
2005 Segal JP, Stallings NR, Lee CE, Zhao L, Socci N, Viale A, Harris TM, Soares MB, Childs G, Elmquist JK, Parker KL, Friedman JM. Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4181-8. PMID 15843621 DOI: 10.1523/Jneurosci.0158-05.2005  1
2005 Alwan S, Tredwell SJ, Friedman JM. Is osseous dysplasia a primary feature of neurofibromatosis 1 (NF1)? Clinical Genetics. 67: 378-90. PMID 15811002 DOI: 10.1111/j.1399-0004.2005.00410.x  1
2005 Kavanaugh JS, Rogers PH, Arnone A, Hui HL, Wierzba A, DeYoung A, Kwiatkowski LD, Noble RW, Juszczak LJ, Peterson ES, Friedman JM. Intersubunit interactions associated with Tyr42 alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin. Biochemistry. 44: 3806-20. PMID 15751957 DOI: 10.1021/Bi0484670  1
2005 Montez JM, Soukas A, Asilmaz E, Fayzikhodjaeva G, Fantuzzi G, Friedman JM. Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 102: 2537-42. PMID 15699332 DOI: 10.1073/Pnas.0409530102  1
2005 Kishi T, Aschkenasi CJ, Choi BJ, Lopez ME, Lee CE, Liu H, Hollenberg AN, Friedman JM, Elmquist JK. Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. The Journal of Comparative Neurology. 482: 217-43. PMID 15690487 DOI: 10.1002/Cne.20432  1
2005 Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 146: 2157-64. PMID 15677756 DOI: 10.1210/En.2004-1572  1
2005 Alwan S, Polifka JE, Friedman JM. Angiotensin II receptor antagonist treatment during pregnancy. Birth Defects Research. Part a, Clinical and Molecular Teratology. 73: 123-30. PMID 15669052 DOI: 10.1002/bdra.20102  1
2005 Lammert M, Friedman JM, Kluwe L, Mautner VF. Prevalence of neurofibromatosis 1 in German children at elementary school enrollment. Archives of Dermatology. 141: 71-4. PMID 15655144 DOI: 10.1001/archderm.141.1.71  1
2005 Cohen P, Yang G, Yu X, Soukas AA, Wolfish CS, Friedman JM, Li C. Induction of leptin receptor expression in the liver by leptin and food deprivation. The Journal of Biological Chemistry. 280: 10034-9. PMID 15644325 DOI: 10.1074/Jbc.M413684200  1
2005 Milani M, Pesce A, Nardini M, Ouellet H, Ouellet Y, Dewilde S, Bocedi A, Ascenzi P, Guertin M, Moens L, Friedman JM, Wittenberg JB, Bolognesi M. Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins. Journal of Inorganic Biochemistry. 99: 97-109. PMID 15598494 DOI: 10.1016/J.Jinorgbio.2004.10.035  1
2005 Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 288: E599-607. PMID 15562249 DOI: 10.1152/Ajpendo.00439.2004  1
2005 Khosrotehrani K, Bastuji-Garin S, Riccardi VM, Birch P, Friedman JM, Wolkenstein P. Subcutaneous neurofibromas are associated with mortality in neurofibromatosis 1: a cohort study of 703 patients. American Journal of Medical Genetics. Part A. 132: 49-53. PMID 15523617 DOI: 10.1002/ajmg.a.30394  1
2005 Brown M, Flier J, Friedman J, Goldstein J, Kahn CR, Lifton R, O'Rahilly S, Spiegelman B. Cell Metabolism: Why, and why now? Cell Metabolism. 1: 3. DOI: 10.1016/J.Cmet.2004.12.007  1
2004 Wolfrum C, Asilmaz E, Luca E, Friedman JM, Stoffel M. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature. 432: 1027-32. PMID 15616563 DOI: 10.1038/Nature03047  1
2004 Friedman JM. Post-traumatic vertigo. Medicine and Health, Rhode Island. 87: 296-300. PMID 15559380  0.01
2004 Samuni U, Dantsker D, Juszczak LJ, Bettati S, Ronda L, Mozzarelli A, Friedman JM. Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels. Biochemistry. 43: 13674-82. PMID 15504030 DOI: 10.1021/Bi048531D  1
2004 Tsuneshige A, Kanaori K, Samuni U, Danstker D, Friedman JM, Neya S, Giangiacomo L, Yonetani T. Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers. The Journal of Biological Chemistry. 279: 48959-67. PMID 15361521 DOI: 10.1074/Jbc.M405909200  1
2004 Cohen P, Friedman JM. Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). The Journal of Nutrition. 134: 2455S-2463S. PMID 15333742 DOI: 10.1093/Jn/134.9.2455S  1
2004 Pham T, Lai D, Ji D, Tuntiwechapikul W, Friedman JM, Lee TR. Well-ordered self-assembled monolayer surfaces can be used to enhance the growth of protein crystals. Colloids and Surfaces. B, Biointerfaces. 34: 191-6. PMID 15261074 DOI: 10.1016/J.Colsurfb.2004.01.003  1
2004 Dantsker D, Samuni U, Ouellet Y, Wittenberg BA, Wittenberg JB, Milani M, Bolognesi M, Guertin M, Friedman JM. Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 279: 38844-53. PMID 15234986 DOI: 10.1074/Jbc.M401513200  1
2004 Sehayek E, Yu HJ, von Bergmann K, Lutjohann D, Stoffel M, Duncan EM, Garcia-Naveda L, Salit J, Blundell ML, Friedman JM, Breslow JL. Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels. Journal of Lipid Research. 45: 1608-13. PMID 15210841 DOI: 10.1194/Jlr.M400006-Jlr200  1
2004 Manjula BN, Tsai AG, Intaglietta M, Tsai CH, Ho C, Malavalli A, Vandegriff KD, Winslow RM, Smith PK, Perumalsamy K, Devi Kanika N, Friedman JM, Acharya SA. WITHDRAWN: PEGylated hemoglobin: Role of surface configuration of PEG for the modulation of hemoglobin vasoactivity. The Journal of Biological Chemistry. PMID 15194702 DOI: 10.1074/jbc.M403468200  1
2004 Baser ME, Kuramoto L, Joe H, Friedman JM, Wallace AJ, Gillespie JE, Ramsden RT, Evans DG. Genotype-phenotype correlations for nervous system tumors in neurofibromatosis 2: a population-based study. American Journal of Human Genetics. 75: 231-9. PMID 15190457 DOI: 10.1086/422700  1
2004 Friedman JM. Modern science versus the stigma of obesity. Nature Medicine. 10: 563-9. PMID 15170194 DOI: 10.1038/Nm0604-563  1
2004 Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proceedings of the National Academy of Sciences of the United States of America. 101: 6409-14. PMID 15096593 DOI: 10.1073/Pnas.0401627101  1
2004 Peterson ES, Shinder R, Khan I, Juczszak L, Wang J, Manjula B, Acharya SA, Bonaventura C, Friedman JM. Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. Biochemistry. 43: 4832-43. PMID 15096052 DOI: 10.1021/Bi035481O  1
2004 Pinto S, Roseberry AG, Liu H, Diano S, Shanabrough M, Cai X, Friedman JM, Horvath TL. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science (New York, N.Y.). 304: 110-5. PMID 15064421 DOI: 10.1126/Science.1089459  1
2004 Roseberry AG, Liu H, Jackson AC, Cai X, Friedman JM. Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron. 41: 711-22. PMID 15003171 DOI: 10.1016/S0896-6273(04)00074-1  1
2004 Samuni U, Ouellet Y, Guertin M, Friedman JM, Yeh SR. The absence of proximal strain in the truncated hemoglobins from Mycobacterium tuberculosis. Journal of the American Chemical Society. 126: 2682-3. PMID 14995168 DOI: 10.1021/Ja038093I  1
2004 Palmer C, Szudek J, Joe H, Riccardi VM, Friedman JM. Analysis of neurofibromatosis 1 (NF1) lesions by body segment. American Journal of Medical Genetics. Part A. 125: 157-61. PMID 14981716 DOI: 10.1002/Ajmg.A.20354  1
2004 Birch P, Friedman JM. Utility and limitations of genetic disease databases in clinical genetics research: a neurofibromatosis 1 database example. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 125: 42-9. PMID 14755433 DOI: 10.1002/ajmg.c.30007  1
2004 Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. The Journal of Clinical Investigation. 113: 414-24. PMID 14755338 DOI: 10.1172/Jci19511  1
2004 Scialli AR, Buelke-Sam JL, Chambers CD, Friedman JM, Kimmel CA, Polifka JE, Tassinari MS. Communicating risks during pregnancy: a workshop on the use of data from animal developmental toxicity studies in pregnancy labels for drugs. Birth Defects Research. Part a, Clinical and Molecular Teratology. 70: 7-12. PMID 14745889 DOI: 10.1002/bdra.10150  1
2004 Das TK, Samuni U, Lin Y, Goldberg DE, Rousseau DL, Friedman JM. Distal heme pocket conformers of carbonmonoxy derivatives of Ascaris hemoglobin: evidence of conformational trapping in porous sol-gel matrices. The Journal of Biological Chemistry. 279: 10433-41. PMID 14688246 DOI: 10.1074/Jbc.M309590200  1
2004 SIEGMUND B, SENNELLO JA, ASILMAZ E, FRIEDMAN JM, FANTUZZI G. ROLE OF LEPTIN IN ACUTE PANCREATITIS INDUCED BY IL-12 AND IL-18 Shock. 21: 35. DOI: 10.1097/00024382-200403001-00140  0.01
2004 Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD. Revisiting the Clinical Validity of Multiplex Genetic Testing in Complex Diseases: Reply to Janssens et al. [3] American Journal of Human Genetics. 74: 588-589. DOI: 10.1086/382054  1
2003 Cohen P, Ntambi JM, Friedman JM. Stearoyl-CoA desaturase-1 and the metabolic syndrome. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 3: 271-80. PMID 14683458 DOI: 10.2174/1568008033340117  1
2003 Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14531-6. PMID 14581619 DOI: 10.1073/Pnas.2235619100  1
2003 Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13698-703. PMID 14581612 DOI: 10.1073/Pnas.1735416100  1
2003 Baser ME, Kuramoto L, Joe H, Friedman JM, Wallace AJ, Ramsden RT, Evans DG. Genotype-phenotype correlations for cataracts in neurofibromatosis 2. Journal of Medical Genetics. 40: 758-60. PMID 14569124 DOI: 10.1136/Jmg.40.10.758  1
2003 Haqq AM, René P, Kishi T, Khong K, Lee CE, Liu H, Friedman JM, Elmquist JK, Cone RD. Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. The Biochemical Journal. 376: 595-605. PMID 14531729 DOI: 10.1042/Bj20031241  1
2003 Acharya SA, Malavalli A, Peterson E, Sun PD, Ho C, Prabhakaran M, Arnone A, Manjula BN, Friedman JM. Probing the conformation of hemoglobin presbyterian in the R-state. Journal of Protein Chemistry. 22: 221-30. PMID 12962322 DOI: 10.1023/A:1025080801951  1
2003 Ishii M, Fei H, Friedman JM. Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity. Proceedings of the National Academy of Sciences of the United States of America. 100: 10540-5. PMID 12925742 DOI: 10.1073/Pnas.1334189100  1
2003 Liu H, Kishi T, Roseberry AG, Cai X, Lee CE, Montez JM, Friedman JM, Elmquist JK. Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7143-54. PMID 12904474 DOI: 10.1523/Jneurosci.23-18-07143.2003  1
2003 Samuni U, Juszczak L, Dantsker D, Khan I, Friedman AJ, Pérez-González-de-Apodaca J, Bruno S, Hui HL, Colby JE, Karasik E, Kwiatkowski LD, Mozzarelli A, Noble R, Friedman JM. Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state. Biochemistry. 42: 8272-88. PMID 12846576 DOI: 10.1021/Bi020648J  1
2003 Friedman JM. Implications of research in male-mediated developmental toxicity to clinical counsellors, regulators, and occupational safety officers. Advances in Experimental Medicine and Biology. 518: 219-26. PMID 12817690  0.01
2003 Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM. Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. The Journal of Biological Chemistry. 278: 33904-11. PMID 12815040 DOI: 10.1074/Jbc.M304724200  1
2003 Alon T, Friedman JM, Socci ND. Cytokine-induced patterns of gene expression in skeletal muscle tissue. The Journal of Biological Chemistry. 278: 32324-34. PMID 12750389 DOI: 10.1074/Jbc.M300972200  1
2003 Polifka JE, Friedman JM. Developmental toxicity of ribavirin/IFalpha combination therapy: is the label more dangerous than the drugs? Birth Defects Research. Part a, Clinical and Molecular Teratology. 67: 8-12. PMID 12749379 DOI: 10.1002/bdra.10020  1
2003 Ouellet H, Juszczak L, Dantsker D, Samuni U, Ouellet YH, Savard PY, Wittenberg JB, Wittenberg BA, Friedman JM, Guertin M. Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry. 42: 5764-74. PMID 12741834 DOI: 10.1021/Bi0270337  1
2003 Samuni U, Dantsker D, Ray A, Wittenberg JB, Wittenberg BA, Dewilde S, Moens L, Ouellet Y, Guertin M, Friedman JM. Kinetic modulation in carbonmonoxy derivatives of truncated hemoglobins: the role of distal heme pocket residues and extended apolar tunnel. The Journal of Biological Chemistry. 278: 27241-50. PMID 12736253 DOI: 10.1074/Jbc.M212634200  1
2003 Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, ... ... Friedman JM, et al. Human chromosome 7: DNA sequence and biology. Science (New York, N.Y.). 300: 767-72. PMID 12690205 DOI: 10.1126/Science.1083423  1
2003 Woods R, Friedman JM, Evans DG, Baser ME, Joe H. Exploring the "two-hit hypothesis" in NF2: tests of two-hit and three-hit models of vestibular schwannoma development. Genetic Epidemiology. 24: 265-72. PMID 12687643 DOI: 10.1002/Gepi.10238  1
2003 Rasmussen SA, Wong LY, Yang Q, May KM, Friedman JM. Population-based analyses of mortality in trisomy 13 and trisomy 18. Pediatrics. 111: 777-84. PMID 12671111  1
2003 Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, Cohen P, Del Prato S, Friedman JM, Maffei M. Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. Journal of Cellular Physiology. 195: 309-21. PMID 12652657 DOI: 10.1002/Jcp.10253  1
2003 Manjula BN, Tsai A, Upadhya R, Perumalsamy K, Smith PK, Malavalli A, Vandegriff K, Winslow RM, Intaglietta M, Prabhakaran M, Friedman JM, Acharya AS. Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chain. Bioconjugate Chemistry. 14: 464-72. PMID 12643758 DOI: 10.1021/Bc0200733  1
2003 Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, Wu ZQ, Borad MJ, Frantzen M, Roussos E, Neeser J, Mikail A, Adams J, Sjak-Shie N, Vescio RA, et al. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1136-44. PMID 12631619  0.08
2003 Yang Q, Khoury MJ, Friedman JM, Flanders WD. On the use of population attributable fraction to determine sample size for case-control studies of gene-environment interaction. Epidemiology (Cambridge, Mass.). 14: 161-7. PMID 12606881 DOI: 10.1097/01.EDE.0000040256.22618.12  1
2003 Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, ... Friedman JM, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37: 649-61. PMID 12597862 DOI: 10.1016/S0896-6273(03)00063-1  1
2003 Szudek J, Evans DG, Friedman JM. Patterns of associations of clinical features in neurofibromatosis 1 (NF1). Human Genetics. 112: 289-97. PMID 12596053 DOI: 10.1007/s00439-002-0871-7  1
2003 Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD. Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes. American Journal of Human Genetics. 72: 636-49. PMID 12592605 DOI: 10.1086/367923  1
2003 Friedman JM. A war on obesity, not the obese. Science (New York, N.Y.). 299: 856-8. PMID 12574619 DOI: 10.1126/Science.1079856  0.01
2003 Huang YY, Oquendo MA, Friedman JM, Greenhill LL, Brodsky B, Malone KM, Khait V, Mann JJ. Substance abuse disorder and major depression are associated with the human 5-HT1B receptor gene (HTR1B) G861C polymorphism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 163-9. PMID 12496953 DOI: 10.1038/sj.npp.1300000  1
2003 Juszczak LJ, Fablet C, Baudin-Creuza V, Lesecq-Le Gall S, Hirsch RE, Nagel RL, Friedman JM, Pagnier J. Conformational changes in hemoglobin S (betaE6V) imposed by mutation of the beta Glu7-beta Lys132 salt bridge and detected by UV resonance Raman spectroscopy. The Journal of Biological Chemistry. 278: 7257-63. PMID 12488314 DOI: 10.1074/Jbc.M200691200  1
2003 Navati MS, Samuni U, Aisen P, Friedman JM. Binding and release of iron by gel-encapsulated human transferrin: evidence for a conformational search. Proceedings of the National Academy of Sciences of the United States of America. 100: 3832-7. PMID 12486226 DOI: 10.1073/Pnas.262526399  1
2002 Baser ME, Friedman JM, Wallace AJ, Ramsden RT, Joe H, Evans DG. Evaluation of clinical diagnostic criteria for neurofibromatosis 2. Neurology. 59: 1759-65. PMID 12473765 DOI: 10.1212/01.Wnl.0000035638.74084.F4  1
2002 Tucker T, Friedman JM. Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis. Clinical Genetics. 62: 345-57. PMID 12431247  1
2002 Friedman JM. Neurofibromatosis 1: clinical manifestations and diagnostic criteria. Journal of Child Neurology. 17: 548-54; discussion 5. PMID 12403552  0.01
2002 Friedman JM. The function of leptin in nutrition, weight, and physiology. Nutrition Reviews. 60: S1-14; discussion S6. PMID 12403078 DOI: 10.1301/002966402320634878  0.01
2002 Zhao Y, Kumar RA, Baser ME, Evans DG, Wallace A, Kluwe L, Mautner VF, Parry DM, Rouleau GA, Joe H, Friedman JM. Intrafamilial correlation of clinical manifestations in neurofibromatosis 2 (NF2). Genetic Epidemiology. 23: 245-59. PMID 12384977 DOI: 10.1002/Gepi.10181  1
2002 Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proceedings of the National Academy of Sciences of the United States of America. 99: 11482-6. PMID 12177411 DOI: 10.1073/Pnas.132384699  1
2002 Han Z, Heath SC, Shmulewitz D, Li W, Auerbach SB, Blundell ML, Lehner T, Ott J, Stoffel M, Friedman JM, Breslow JL. Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. American Journal of Medical Genetics. 110: 234-42. PMID 12116231 DOI: 10.1002/Ajmg.10445  1
2002 Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (New York, N.Y.). 297: 240-3. PMID 12114623 DOI: 10.1126/Science.1071527  1
2002 Chiellini C, Bertacca A, Novelli SE, Görgün CZ, Ciccarone A, Giordano A, Xu H, Soukas A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego L, ... ... Friedman JM, et al. Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. Journal of Cellular Physiology. 190: 251-8. PMID 11807829 DOI: 10.1002/Jcp.10061  1
2002 Friedman J. Fat in all the wrong places Nature. 415: 268-269. PMID 11796987 DOI: 10.1038/415268A  1
2001 Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, Friedman JM. Selective deletion of leptin receptor in neurons leads to obesity. The Journal of Clinical Investigation. 108: 1113-21. PMID 11602618 DOI: 10.1172/Jci13914  1
2001 Soukas A, Socci ND, Saatkamp BD, Novelli S, Friedman JM. Distinct transcriptional profiles of adipogenesis in vivo and in vitro. The Journal of Biological Chemistry. 276: 34167-74. PMID 11445576 DOI: 10.1074/jbc.M104421200  1
2001 DeFalco J, Tomishima M, Liu H, Zhao C, Cai X, Marth JD, Enquist L, Friedman JM. Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus. Science (New York, N.Y.). 291: 2608-13. PMID 11283374 DOI: 10.1126/Science.1056602  1
2001 Shmulewitz D, Auerbach SB, Lehner T, Blundell ML, Winick JD, Youngman LD, Skilling V, Heath SC, Ott J, Stoffel M, Breslow JL, Friedman JM. Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Human Heredity. 51: 8-19. PMID 11096265 DOI: 10.1159/000022953  1
2000 Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 103: 525-35. PMID 11081638 DOI: 10.1016/S0092-8674(00)00143-4  1
2000 Lin AE, Birch PH, Korf BR, Tenconi R, Niimura M, Poyhonen M, Uhas KA, Sigorini M, Virdis R, Romano C, Bonioli E, Wolkenstein P, Pivnick EK, Lawrence M, Friedman JM. Cardiovascular malformations and other cardiovascular abnormalities in neurofibromatosis 1 American Journal of Medical Genetics. 95: 108-117. PMID 11078559 DOI: 10.1002/1096-8628(20001113)95:2<108::Aid-Ajmg4>3.0.Co;2-0  1
2000 Yoon JC, Chickering TW, Rosen ED, Dussault B, Qin Y, Soukas A, Friedman JM, Holmes WE, Spiegelman BM. Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Molecular and Cellular Biology. 20: 5343-9. PMID 10866690 DOI: 10.1128/Mcb.20.14.5343-5349.2000  1
2000 Soukas A, Cohen P, Socci ND, Friedman JM. Leptin-specific patterns of gene expression in white adipose tissue. Genes & Development. 14: 963-80. PMID 10783168 DOI: 10.1101/Gad.14.8.963  1
2000 Friedman JM. Obesity in the new millennium. Nature. 404: 632-634. PMID 10766249 DOI: 10.1038/35007504  0.01
2000 FRIEDMAN J. LEPTIN AND THE NEURAL CIRCUIT REGULATING BODY WEIGHT Biochemical Society Transactions. 28: A104-A104. DOI: 10.1042/BST028A104B  0.01
1999 Li C, Friedman JM. Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 96: 9677-82. PMID 10449753 DOI: 10.1073/Pnas.96.17.9677  0.04
1999 Burcelin R, Kamohara S, Li J, Tannenbaum GS, Charron MJ, Friedman JM. Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice. Diabetes. 48: 1264-9. PMID 10342814 DOI: 10.2337/Diabetes.48.6.1264  1
1999 Soukas A, Cohen P, Friedman JM. Gene expression profile induced by leptin in white adipose tissue and liver Nature Genetics. 23: 75-75. DOI: 10.1038/14405  0.36
1998 Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 395: 763-70. PMID 9796811 DOI: 10.1038/27376  1
1998 Ioffe E, Moon B, Connolly E, Friedman JM. Abnormal regulation of the leptin gene in the pathogenesis of obesity. Proceedings of the National Academy of Sciences of the United States of America. 95: 11852-7. PMID 9751754 DOI: 10.1073/Pnas.95.20.11852  0.16
1998 Winick JD, Friedman JM. Microsatellite Marker Content Mapping of 12 Candidate Genes for Obesity: Assembly of Seven Obesity Screening Panels for Automated Genotyping Genome Research. 8: 985-994. PMID 9750197 DOI: 10.1101/Gr.8.9.985  1
1998 Friedman JM. Leptin, leptin receptors, and the control of body weight. Nutrition Reviews. 56: s38-46; discussion s. PMID 9564176 DOI: 10.1111/J.1753-4887.1998.Tb01685.X  0.01
1998 Li C, Ioffe E, Fidahusein N, Connolly E, Friedman JM. Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice. The Journal of Biological Chemistry. 273: 10078-82. PMID 9545355 DOI: 10.1074/Jbc.273.16.10078  0.2
1998 Friedman JM. La leptine, l'obésité des rongeurs et le circuit neuroendocrinien contrôlant le poids corporel Annales De L'Institut Pasteur / ActualitéS. 9: 305-320. DOI: 10.1016/S0924-4204(99)80010-9  0.01
1997 Lee GH, Li C, Montez J, Halaas J, Darvishzadeh J, Friedman JM. Leptin receptor mutations in 129 db (3J)/db(3.J) mice and NIH fa (cp)/fa(cp) rats. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 445-7. PMID 27518443 DOI: 10.1007/S003359900466  1
1997 McFadden DE, Friedman JM. Chromosome abnormalities in human beings. Mutation Research. 396: 129-40. PMID 9434864 DOI: 10.1016/S0027-5107(97)00179-6  1
1997 Halaas JL, Friedman JM. Leptin and its receptor. The Journal of Endocrinology. 155: 215-6. PMID 9415051 DOI: 10.1677/Joe.0.1550215  1
1997 Kamohara S, Burcelin R, Halaas JL, Friedman JM, Charron MJ. Acute stimulation of glucose metabolism in mice by leptin treatment. Nature. 389: 374-7. PMID 9311777 DOI: 10.1038/38717  1
1997 Weinstock PH, Levak-Frank S, Hudgins LC, Radner H, Friedman JM, Zechner R, Breslow JL. Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America. 94: 10261-6. PMID 9294198 DOI: 10.1073/Pnas.94.19.10261  0.01
1997 Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 8878-83. PMID 9238071 DOI: 10.1073/Pnas.94.16.8878  1
1997 Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proceedings of the National Academy of Sciences of the United States of America. 94: 7001-5. PMID 9192681 DOI: 10.1073/Pnas.94.13.7001  1
1997 Moon BC, Friedman JM. The molecular basis of the obese mutation in ob2J mice. Genomics. 42: 152-156. PMID 9177786 DOI: 10.1006/Geno.1997.4701  0.4
1997 Ravussin E, Pratley RE, Maffei M, Wang H, Friedman JM, Bennett PH, Bogardus C. Relatively low plasma leptin concentrations precede weight gain in Pima Indians. Nature Medicine. 3: 238-40. PMID 9018247 DOI: 10.1038/Nm0297-238  0.04
1997 Friedman JM. The alphabet of weight control. Nature. 385: 119-20. PMID 8990109 DOI: 10.1038/385119A0  0.01
1996 Winick JD, Stoffel M, Friedman JM. Identification of microsatellite markers linked to the human leptin receptor gene on chromosome 1. Genomics. 36: 221-2. PMID 8812446 DOI: 10.1006/Geno.1996.0455  1
1996 Vaisse C, Halaas JL, Horvath CM, Darnell JE, Stoffel M, Friedman JM. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nature Genetics. 14: 95-7. PMID 8782827 DOI: 10.1038/Ng0996-95  1
1996 Cohen SL, Halaas JL, Friedman JM, Chalt BT, Bennett L, Chang D, Hecht R, Collins F. Human leptin characterization Nature. 382: 589. PMID 8757126 DOI: 10.1038/382589A0  1
1996 Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM. Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379: 632-5. PMID 8628397 DOI: 10.1038/379632A0  1
1996 Maffei M, Stoffel M, Barone M, Moon B, Dammerman M, Ravussin E, Bogardus C, Ludwig DS, Flier JS, Talley M, Auerbach S, Friedman JM. Absence of mutations in the human OB gene in obese/diabetic subjects Diabetes. 45: 679-682. PMID 8621022 DOI: 10.2337/Diab.45.5.679  1
1996 Leroy P, Dessolin S, Villageois P, Moon BC, Friedman JM, Ailhaud G, Dani C. Expression of ob gene in adipose cells. Regulation by insulin. The Journal of Biological Chemistry. 271: 2365-8. PMID 8576190 DOI: 10.1074/Jbc.271.5.2365  0.08
1995 Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM. Weight-reducing effects of the plasma protein encoded by the obese gene. Science (New York, N.Y.). 269: 543-6. PMID 7624777 DOI: 10.1126/Science.7624777  1
1995 Maffei M, Fei H, Lee GH, Dani C, Leroy P, Zhang Y, Proenca R, Negrel R, Ailhaud G, Friedman JM. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proceedings of the National Academy of Sciences of the United States of America. 92: 6957-60. PMID 7624352 DOI: 10.1073/Pnas.92.15.6957  1
1995 Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Medicine. 1: 1155-61. PMID 7584987 DOI: 10.1038/Nm1195-1155  0.4
1995 Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue Nature. 374: 479-479. DOI: 10.1038/374479a0  0.04
1994 Friedman JM. Obesity. Brown fat and yellow mice. Nature. 366: 720-1. PMID 8264793 DOI: 10.1038/366720A0  0.01
1994 Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 372: 425-32. PMID 7984236 DOI: 10.1038/372425A0  1
1993 Leibel RL, Bahary N, Friedman JM. Strategies for the molecular genetic analysis of obesity in humans. Critical Reviews in Food Science and Nutrition. 33: 351-8. PMID 8357496 DOI: 10.1080/10408399309527632  1
1993 Abbott CM, Blank R, Eppig JT, Fiedorek FT, Frankel W, Friedman JM, Huppi KE, Jackson I, Steel K, Mock BA. Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 4. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: S58-71. PMID 8268685 DOI: 10.1007/Bf00360830  1
1993 Novick DM, Richman BL, Friedman JM, Friedman JE, Fried C, Wilson JP, Townley A, Kreek MJ. The medical status of methadone maintenance patients in treatment for 11-18 years Drug and Alcohol Dependence. 33: 235-245. PMID 8261888 DOI: 10.1016/0376-8716(93)90110-C  1
1993 Bahary N, McGraw DE, Shilling R, Friedman JM. Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. Genomics. 16: 113-22. PMID 8098006 DOI: 10.1006/Geno.1993.1148  1
1993 Bahary N, Siegel DA, Walsh J, Zhang Y, Leopold L, Leibel R, Proenca R, Friedman JM. Microdissection of proximal mouse chromosome 6: identification of RFLPs tightly linked to the ob mutation. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 511-5. PMID 7906968 DOI: 10.1007/Bf00364786  1
1992 Blank R, Eppig J, Fiedorek FT, Frankel WN, Friedman JM, Huppi K, Jackson I, Mock B. Mouse chromosome 4. Mammalian Genome : Official Journal of the International Mammalian Genome Society. S51-78. PMID 1799812 DOI: 10.1007/Bf00656486  0.01
1992 Friedman JM, Leibel RL, Bahary N. Molecular mapping of obesity genes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 1: 130-44. PMID 1797227 DOI: 10.1007/Bf00351059  0.01
1992 Friedman JM, Leibel RL, Siegel DS, Walsh J, Bahary N. Molecular mapping of the mouse ob mutation. Genomics. 11: 1054-62. PMID 1686014 DOI: 10.1016/0888-7543(91)90032-A  0.04
1992 Friedman JM, Vitale M, Maimon J, Israel MA, Horowitz ME, Schneider BS. Expression of the cholecystokinin gene in pediatric tumors. Proceedings of the National Academy of Sciences of the United States of America. 89: 5819-23. PMID 1631063 DOI: 10.1073/Pnas.89.13.5819  1
1992 Friedman JM, Leibel RL. Tackling a weighty problem. Cell. 69: 217-20. PMID 1568242 DOI: 10.1016/0092-8674(92)90402-X  0.08
1992 Abbott CM, Blank R, Eppig JT, Friedman JM, Huppi KE, Jackson I, Mock BA, Stoye J, Wiseman R. Mouse chromosome 4. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 3: S55-64. PMID 1498443 DOI: 10.1007/BF00648422  1
1992 Cornall RJ, Friedman JM, Todd JA. Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome Mammalian Genome. 3: 620-624. PMID 1450512 DOI: 10.1007/Bf00352478  1
1991 Vitale M, Vashishtha A, Linzer E, Powell DJ, Friedman JM. Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development Nucleic Acids Research. 19: 169-177. PMID 2011497 DOI: 10.1093/Nar/19.1.169  1
1991 Truett GE, Bahary N, Friedman JM, Leibel RL. Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). Proceedings of the National Academy of Sciences of the United States of America. 88: 7806-9. PMID 1881916 DOI: 10.1073/Pnas.88.17.7806  1
1991 Bahary N, Zorich G, Pachter JE, Leibel RL, Friedman JM. Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics. 11: 33-47. PMID 1684952 DOI: 10.1016/0888-7543(91)90099-Z  1
1991 Friedman JM, Leibel RL, Bahary N, Siegel DA, Truett G. Genetic analysis of complex disorders. Molecular mapping of obesity genes in mice and humans. Annals of the New York Academy of Sciences. 630: 100-15. PMID 1683202 DOI: 10.1111/J.1749-6632.1991.Tb19579.X  1
1990 Babiss LE, Friedman JM. Regulation of N-myc gene expression: use of an adenovirus vector to demonstrate posttranscriptional control. Molecular and Cellular Biology. 10: 6700-8. PMID 2147226 DOI: 10.1128/Mcb.10.12.6700  1
1990 Bahary N, Leibel RL, Joseph L, Friedman JM. Molecular mapping of the mouse db mutation. Proceedings of the National Academy of Sciences of the United States of America. 87: 8642-6. PMID 1978328 DOI: 10.1073/Pnas.87.21.8642  1
1990 Leibel RL, Bahary N, Friedman JM. Genetic variation and nutrition in obesity: approaches to the molecular genetics of obesity. World Review of Nutrition and Dietetics. 63: 90-101. PMID 1973864 DOI: 10.1159/000418501  0.01
1989 Schneider BS, Helson L, Monahan JW, Friedman JM. Expression of the cholecystokinin gene by cultured human primitive neuroepithelioma cell lines. The Journal of Clinical Endocrinology and Metabolism. 69: 411-9. PMID 2753982 DOI: 10.1210/Jcem-69-2-411  1
1989 Friedman JM, Schneider BS, Barton DE, Francke U. Level of expression and chromosome mapping of the mouse cholecystokinin gene: implications for murine models of genetic obesity. Genomics. 5: 463-9. PMID 2575582 DOI: 10.1016/0888-7543(89)90010-4  1
1989 Xanthopoulos KG, Mirkovitch J, Friedman JM, Darnell JE. The mouse Cebp gene encoding a DNA-binding protein is polymorphic and is located on chromosome 7. Cytogenetics and Cell Genetics. 50: 174-5. PMID 2570675  1
1987 Babiss LE, Friedman JM, Darnell JE. Cellular promoters incorporated into the adenovirus genome. Effect of viral DNA replication on endogenous and exogenous gene transcription. Journal of Molecular Biology. 193: 643-50. PMID 3612788 DOI: 10.1016/0022-2836(87)90347-0  1
1987 Friedman JM, Babiss LE, Weiss M, Darnell JE. Hepatoma variants (C2) are defective for transcriptional and post-transcriptional actions from both endogenous and viral genomes. The Embo Journal. 6: 1727-31. PMID 2956094 DOI: 10.1002/J.1460-2075.1987.Tb02424.X  1
1987 Schweigerer L, Neufeld G, Friedman J, Abraham JA, Fiddes JC, Gospodarowicz D. Basic fibroblast growth factor: production and growth stimulation in cultured adrenal cortex cells. Endocrinology. 120: 796-800. PMID 2879725 DOI: 10.1210/Endo-120-2-796  1
1987 Schweigerer L, Neufeld G, Friedman J, Abraham JA, Fiddes JC, Gospodarowicz D. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature. 325: 257-9. PMID 2433585 DOI: 10.1038/325257A0  1
1986 Schneider BS, Mainon J, Friedman J. Expression of a cholecystokinin precursor-related peptide in vertebrate and invertebrate tissues American Journal of Physiology - Endocrinology and Metabolism. 251. PMID 3789138 DOI: 10.1152/Ajpendo.1986.251.6.E707  1
1986 Babiss LE, Bennett A, Friedman JM, Darnell JE. DNase I-hypersensitive sites in the 5'-flanking region of the rat serum albumin gene: correlation between chromatin structure and transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. 83: 6504-8. PMID 3462709 DOI: 10.1073/Pnas.83.17.6504  1
1986 Babiss LE, Friedman JM, Darnell JE. Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters. Molecular and Cellular Biology. 6: 3798-806. PMID 2948109 DOI: 10.1128/Mcb.6.11.3798  1
1986 Friedman JM, Babiss LE, Clayton DF, Darnell JE. Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression. Molecular and Cellular Biology. 6: 3791-7. PMID 2948108 DOI: 10.1128/Mcb.6.11.3791  1
1986 Abraham JA, Mergia A, Whang JL, Tumolo A, Friedman J, Hjerrild KA, Gospodarowicz D, Fiddes JC. Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor Science. 233: 545-548. PMID 2425435 DOI: 10.1126/Science.2425435  1
1985 Friedman J, Schneider BS, Powell D. Differential expression of the mouse cholecystokinin gene during brain and gut development Proceedings of the National Academy of Sciences of the United States of America. 82: 5593-5597. PMID 3862083 DOI: 10.1073/Pnas.82.17.5593  1
1984 Friedman JM, Chung EY, Darnell JE. Gene expression during liver regeneration. Journal of Molecular Biology. 179: 37-53. PMID 6502711 DOI: 10.1016/0022-2836(84)90305-X  1
1984 Powell DJ, Friedman JM, Oulette AJ, Krauter KS, Darnell JE. Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver. Journal of Molecular Biology. 179: 21-35. PMID 6502710 DOI: 10.1016/0022-2836(84)90304-8  1
1979 Harrod MJE, Friedman JM, Jimenez J, Santos-Ramos R, Byrne JB, Dev VG, Weinberg AG. RAPIDLY ADHERING AMNIOTIC-FLUID CELLS AND PRENATAL DIAGNOSIS OF NEURAL-TUBE DEFECTS The Lancet. 314: 99. PMID 87993 DOI: 10.1016/S0140-6736(79)90150-8  1
1978 Friedman J, Lewy JE. 1065 PATHOPHYSIOLOGY OF CHRONIC HEREDITARY HYDRONEPHROSIS IN THE RAT Pediatric Research. 12: 541-541. DOI: 10.1203/00006450-197804001-01071  0.01
1977 Pachman LM, Jonasson O, Cannon RA, Friedman JM. HLA-B8 in juvenile dermatomyositis. Lancet. 2: 567-8. PMID 95783 DOI: 10.1016/S0140-6736(77)90716-4  1
1977 Pachman LM, Jonasson O, Cannon RA, Friedman JM. Increased frequency of HLA-B8 in juvenile dermatomyositis. Lancet. 2: 1238. PMID 73944 DOI: 10.1016/S0140-6736(77)90487-1  1
1976 Friedman JM. Letter: Inheritance of susceptibility to histocompatibility-associated disease. Lancet (London, England). 1: 49. PMID 54563 DOI: 10.1016/S0140-6736(76)92960-3  0.01
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