cached image

Jeffrey M. Friedman - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
molecular mechanisms that regulate food intake and body weight
Website:
http://www.rockefeller.edu/research/faculty/abstract.php?id=41

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Schneeberger M, Parolari L, Das Banerjee T, Bhave V, Wang P, Patel B, Topilko T, Wu Z, Choi CHJ, Yu X, Pellegrino K, Engel EA, Cohen P, Renier N, Friedman JM, et al. Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell. PMID 31257028 DOI: 10.1016/j.cell.2019.05.048  0.96
2019 Azevedo EP, Pomeranz L, Cheng J, Schneeberger M, Vaughan R, Stern SA, Tan B, Doerig K, Greengard P, Friedman JM. A Role of Drd2 Hippocampal Neurons in Context-Dependent Food Intake. Neuron. PMID 30930044 DOI: 10.1016/j.neuron.2019.03.011  0.52
2019 Dallner OS, Marinis JM, Lu YH, Birsoy K, Werner E, Fayzikhodjaeva G, Dill BD, Molina H, Moscati A, Kutalik Z, Marques-Vidal P, Kilpeläinen TO, Grarup N, Linneberg A, Zhang Y, ... ... Friedman JM, et al. Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity. Nature Medicine. PMID 30842678 DOI: 10.1038/s41591-019-0370-1  0.88
2018 Zhang H, Chaudhury D, Nectow AR, Friedman AK, Zhang S, Juarez B, Liu H, Pfau ML, Aleyasin H, Jiang C, Crumiller M, Calipari ES, Ku SM, Morel C, Tzavaras N, ... ... Friedman JM, et al. α- and β-Adrenergic Receptor-Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice. Biological Psychiatry. PMID 30336931 DOI: 10.1016/j.biopsych.2018.08.020  0.52
2018 Zhang Y, Dallner OS, Nakadai T, Fayzikhodjaeva G, Lu YH, Lazar MA, Roeder RG, Friedman JM. A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891714 DOI: 10.1073/pnas.1806366115  0.88
2018 Stern SA, Doerig KR, Azevedo EP, Stoffel E, Friedman JM. Control of non-homeostatic feeding in sated mice using associative learning of contextual food cues. Molecular Psychiatry. PMID 29875477 DOI: 10.1038/s41380-018-0072-y  0.52
2018 Schneeberger M, Tan K, Nectow AR, Parolari L, Caglar C, Azevedo E, Li Z, Domingos A, Friedman JM. Functional analysis reveals differential effects of glutamate and MCH neuropeptide in MCH neurons. Molecular Metabolism. PMID 29843980 DOI: 10.1016/j.molmet.2018.05.001  0.64
2018 Calarco CA, Li Z, Taylor SR, Lee S, Zhou W, Friedman JM, Mineur YS, Gotti C, Picciotto MR. Molecular and cellular characterization of nAChR subtypes in the arcuate nucleus of the mouse hypothalamus. The European Journal of Neuroscience. PMID 29791746 DOI: 10.1111/ejn.13966  0.36
2017 Nectow AR, Schneeberger M, Zhang H, Field BC, Renier N, Azevedo E, Patel B, Liang Y, Mitra S, Tessier-Lavigne M, Han MH, Friedman JM. Identification of a Brainstem Circuit Controlling Feeding. Cell. 170: 429-442.e11. PMID 28753423 DOI: 10.1016/j.cell.2017.06.045  0.52
2017 Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/j.celrep.2017.03.048  0.52
2017 Pomeranz LE, Ekstrand MI, Latcha KN, Smith GA, Enquist LW, Friedman JM. Gene expression profiling with Cre-conditional pseudorabies virus reveals a subset of midbrain neurons that participate in reward circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28283558 DOI: 10.1523/JNEUROSCI.3193-16.2017  0.52
2016 Stanley SA, Kelly L, Latcha KN, Schmidt SF, Yu X, Nectow AR, Sauer J, Dyke JP, Dordick JS, Friedman JM. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature. PMID 27007848 DOI: 10.1038/nature17183  0.96
2015 Li Z, Kelly L, Heiman M, Greengard P, Friedman JM. Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. Cell Metabolism. 22: 1059-67. PMID 26655697 DOI: 10.1016/j.cmet.2015.10.012  0.96
2015 Zeng W, Pirzgalska RM, Pereira MM, Kubasova N, Barateiro A, Seixas E, Lu YH, Kozlova A, Voss H, Martins GG, Friedman JM, Domingos AI. Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis. Cell. 163: 84-94. PMID 26406372 DOI: 10.1016/j.cell.2015.08.055  0.96
2015 Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/j.chembiol.2015.07.011  0.96
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405]. Molecular Metabolism. 4: 592. PMID 26266092 DOI: 10.1016/j.molmet.2015.05.004  0.88
2015 Nectow AR, Ekstrand MI, Friedman JM. Molecular characterization of neuronal cell types based on patterns of projection with Retro-TRAP. Nature Protocols. 10: 1319-27. PMID 26247298 DOI: 10.1038/nprot.2015.087  0.96
2015 Zeng W, Lu YH, Lee J, Friedman JM. Reanalysis of parabiosis of obesity mutants in the age of leptin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150485 DOI: 10.1073/pnas.1510378112  0.96
2015 Friedman JM. Editorial. Life Sciences. PMID 26092482 DOI: 10.1016/j.lfs.2015.06.002  0.96
2015 Battula KK, Nappanveettil G, Nakanishi S, Kuramoto T, Friedman JM, Kalashikam RR. Genetic Relatedness of WNIN and WNIN/Ob with Major Rat Strains in Biomedical Research. Biochemical Genetics. 53: 132-40. PMID 25991561 DOI: 10.1007/s10528-015-9679-8  0.96
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression. Molecular Metabolism. 4: 392-405. PMID 25973387 DOI: 10.1016/j.molmet.2015.02.002  0.96
2015 Stanley SA, Sauer J, Kane RS, Dordick JS, Friedman JM. Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nature Medicine. 21: 92-8. PMID 25501906 DOI: 10.1038/nm.3730  0.96
2015 Friedman JM, Mantzoros CS. 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. Metabolism: Clinical and Experimental. 64: 1-4. PMID 25497341 DOI: 10.1016/j.metabol.2014.10.023  0.96
2015 Meko DM, Friedman JM, Touchan R, Edmondson JR, Griffin ER, Scott JA. Alternative standardization approaches to improving streamflow reconstructions with ring-width indices of riparian trees Holocene. 25: 1093-1101. DOI: 10.1177/0959683615580181  0.44
2015 Friedman JM, Vincent KR, Griffin ER, Scott ML, Shafroth PB, Auble GT. Processes of arroyo filling in northern New Mexico, USA Bulletin of the Geological Society of America. 127: 621-640. DOI: 10.1130/B31046.1  0.44
2015 Mcshane RR, Auerbach DA, Friedman JM, Auble GT, Shafroth PB, Merigliano MF, Scott ML, Poff NL. Distribution of invasive and native riparian woody plants across the western USA in relation to climate, river flow, floodplain geometry and patterns of introduction Ecography. 38: 1254-1265. DOI: 10.1111/ecog.01285  0.44
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405] Molecular Metabolism. DOI: 10.1016/j.molmet.2015.05.004  0.96
2015 Liu S, Chen Y, Friedman JM, Hati JHA, Fang G. Use of 2H and 18O stable isotopes to investigate water sources for different ages of Populus euphratica along the lower Heihe River Ecological Research. DOI: 10.1007/s11284-015-1270-6  0.44
2015 Friedman J. Foreword Leptin: Regulation and Clinical Applications. vii-xvi. DOI: 10.1007/978-3-319-09915-6  0.96
2014 Tan K, Knight ZA, Friedman JM. Ablation of AgRP neurons impairs adaption to restricted feeding. Molecular Metabolism. 3: 694-704. PMID 25352998 DOI: 10.1016/j.molmet.2014.07.002  0.68
2014 Knight ZA, Schmidt SF, Birsoy K, Tan K, Friedman JM. A critical role for mTORC1 in erythropoiesis and anemia. Elife. 3: e01913. PMID 25201874 DOI: 10.7554/eLife.01913  0.88
2014 Friedman J. 20 years of leptin: leptin at 20: an overview. The Journal of Endocrinology. 223: T1-8. PMID 25121999 DOI: 10.1530/JOE-14-0405  0.96
2014 Friedman J. Douglas Coleman (1931-2014). Nature. 509: 564. PMID 24870535 DOI: 10.1038/509564a  0.96
2014 Ekstrand MI, Nectow AR, Knight ZA, Latcha KN, Pomeranz LE, Friedman JM. Molecular profiling of neurons based on connectivity. Cell. 157: 1230-42. PMID 24855954 DOI: 10.1016/j.cell.2014.03.059  0.68
2014 Williams WI, Friedman JM, Gaskin JF, Norton AP. Hybridization of an invasive shrub affects tolerance and resistance to defoliation by a biological control agent. Evolutionary Applications. 7: 381-93. PMID 24665340 DOI: 10.1111/eva.12134  0.44
2014 Domingos AI, Vaynshteyn J, Sordillo A, Friedman JM. The reward value of sucrose in leptin-deficient obese mice. Molecular Metabolism. 3: 73-80. PMID 24567906 DOI: 10.1016/j.molmet.2013.10.007  0.96
2014 Walsh JJ, Friedman AK, Sun H, Heller EA, Ku SM, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nature Neuroscience. 17: 27-9. PMID 24270188 DOI: 10.1038/nn.3591  0.96
2014 Griffin ER, Perignon MC, Friedman JM, Tucker GE. Effects of woody vegetation on overbank sand transport during a large flood, Rio Puerco, New Mexico Geomorphology. 207: 30-50. DOI: 10.1016/j.geomorph.2013.10.025  0.44
2013 Domingos AI, Sordillo A, Dietrich MO, Liu ZW, Tellez LA, Vaynshteyn J, Ferreira JG, Ekstrand MI, Horvath TL, de Araujo IE, Friedman JM. Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar. Elife. 2: e01462. PMID 24381247 DOI: 10.7554/eLife.01462  0.96
2013 Li Z, Ceccarini G, Eisenstein M, Tan K, Friedman JM. Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor. Molecular Metabolism. 2: 364-75. PMID 24327953 DOI: 10.1016/j.molmet.2013.07.007  0.96
2013 Kalashikam RR, Battula KK, Kirlampalli V, Friedman JM, Nappanveettil G. Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor. Plos One. 8: e77679. PMID 24204914 DOI: 10.1371/journal.pone.0077679  0.96
2013 le Coutre J, Mattson MP, Dillin A, Friedman J, Bistrian B. Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction. The Journal of Nutrition, Health & Aging. 17: 717-20. PMID 24097030 DOI: 10.1007/s12603-013-0375-2  0.96
2013 Stanley S, Domingos AI, Kelly L, Garfield A, Damanpour S, Heisler L, Friedman J. Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia. Cell Metabolism. 18: 596-607. PMID 24093682 DOI: 10.1016/j.cmet.2013.09.002  0.96
2013 Jego S, Glasgow SD, Herrera CG, Ekstrand M, Reed SJ, Boyce R, Friedman J, Burdakov D, Adamantidis AR. Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus. Nature Neuroscience. 16: 1637-43. PMID 24056699 DOI: 10.1038/nn.3522  0.96
2013 Li Z, Schmidt SF, Friedman JM. Developmental role for endocannabinoid signaling in regulating glucose metabolism and growth. Diabetes. 62: 2359-67. PMID 23423572 DOI: 10.2337/db12-0901  0.96
2013 Murdock D, Salit J, Stoffel M, Friedman JM, Pe'er I, Breslow JL, Bonnen PE. Longitudinal study shows increasing obesity and hyperglycemia in micronesia. Obesity (Silver Spring, Md.). 21: E421-7. PMID 23404778 DOI: 10.1002/oby.20041  0.96
2013 Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... ... Friedman JM, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/nature11713  0.96
2013 Merigliano MF, Friedman JM, Scott ML. Tree-Ring Records of Variation in Flow and Channel Geometry Treatise On Geomorphology. 12: 145-164. DOI: 10.1016/B978-0-12-374739-6.00319-5  0.44
2013 Perignon MC, Tucker GE, Griffin ER, Friedman JM. Effects of riparian vegetation on topographic change during a large flood event, Rio Puerco, New Mexico, USA Journal of Geophysical Research: Earth Surface. 118: 1193-1209. DOI: 10.1002/jgrf.20073  0.44
2012 Knight ZA, Tan K, Birsoy K, Schmidt S, Garrison JL, Wysocki RW, Emiliano A, Ekstrand MI, Friedman JM. Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell. 151: 1126-37. PMID 23178128 DOI: 10.1016/j.cell.2012.10.039  0.96
2012 Friedman J. Leading the charge in leptin research: an interview with Jeffrey Friedman. Disease Models & Mechanisms. 5: 576-9. PMID 22915017 DOI: 10.1242/dmm.010629  0.96
2012 Stanley SA, Gagner JE, Damanpour S, Yoshida M, Dordick JS, Friedman JM. Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science (New York, N.Y.). 336: 604-8. PMID 22556257 DOI: 10.1126/science.1216753  0.96
2012 Gusev A, Shah MJ, Kenny EE, Ramachandran A, Lowe JK, Salit J, Lee CC, Levandowsky EC, Weaver TN, Doan QC, Peckham HE, McLaughlin SF, Lyons MR, Sheth VN, Stoffel M, ... ... Friedman JM, et al. Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population. Genetics. 190: 679-89. PMID 22135348 DOI: 10.1534/genetics.111.134874  0.96
2012 Guilbault KR, Brown CS, Friedman JM, Shafroth PB. The influence of chilling requirement on the southern distribution limit of exotic Russian olive (Elaeagnus angustifolia) in western North America Biological Invasions. 14: 1711-1724. DOI: 10.1007/s10530-012-0182-4  0.44
2011 Domingos AI, Vaynshteyn J, Voss HU, Ren X, Gradinaru V, Zang F, Deisseroth K, de Araujo IE, Friedman J. Leptin regulates the reward value of nutrient. Nature Neuroscience. 14: 1562-8. PMID 22081158 DOI: 10.1038/nn.2977  0.96
2011 Birsoy K, Berry R, Wang T, Ceyhan O, Tavazoie S, Friedman JM, Rodeheffer MS. Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development (Cambridge, England). 138: 4709-19. PMID 21989915 DOI: 10.1242/dev.067710  0.96
2011 Friedman JM, Roelle JE, Cade BS. Genetic and environmental influences on leaf phenology and cold hardiness of native and introduced riparian trees. International Journal of Biometeorology. 55: 775-87. PMID 21927930 DOI: 10.1007/s00484-011-0494-6  0.44
2011 Gusev A, Kenny EE, Lowe JK, Salit J, Saxena R, Kathiresan S, Altshuler DM, Friedman JM, Breslow JL, Pe'er I. DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. American Journal of Human Genetics. 88: 706-17. PMID 21620352 DOI: 10.1016/j.ajhg.2011.04.023  0.96
2011 Friedman JM. Leptin and the regulation of body weigh. The Keio Journal of Medicine. 60: 1-9. PMID 21460597 DOI: 10.2302/kjm.60.1  0.96
2011 Pérez CA, Stanley SA, Wysocki RW, Havranova J, Ahrens-Nicklas R, Onyimba F, Friedman JM. Molecular annotation of integrative feeding neural circuits. Cell Metabolism. 13: 222-32. PMID 21284989 DOI: 10.1016/j.cmet.2010.12.013  0.96
2011 Donato J, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S, Coppari R, Zigman JM, et al. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. The Journal of Clinical Investigation. 121: 355-68. PMID 21183787 DOI: 10.1172/JCI45106  0.96
2011 Kenny EE, Kim M, Gusev A, Lowe JK, Salit J, Smith JG, Kovvali S, Kang HM, Newton-Cheh C, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Eskin E, Breslow JL, et al. Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. Human Molecular Genetics. 20: 827-39. PMID 21118897 DOI: 10.1093/hmg/ddq510  0.96
2010 Friedman JM. A tale of two hormones. Nature Medicine. 16: 1100-6. PMID 20930753 DOI: 10.1038/nm1010-1100  0.96
2010 Knight ZA, Hannan KS, Greenberg ML, Friedman JM. Hyperleptinemia is required for the development of leptin resistance. Plos One. 5: e11376. PMID 20613882 DOI: 10.1371/journal.pone.0011376  0.68
2010 Stanley S, Pinto S, Segal J, Pérez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM. Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically. Proceedings of the National Academy of Sciences of the United States of America. 107: 7024-9. PMID 20351287 DOI: 10.1073/pnas.1002790107  0.96
2010 Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. Antidiabetic effects of IGFBP2, a leptin-regulated gene. Cell Metabolism. 11: 11-22. PMID 20074524 DOI: 10.1016/j.cmet.2009.11.007  0.96
2010 Gautron L, Lee C, Funahashi H, Friedman J, Lee S, Elmquist J. Melanocortin-4 receptor expression in a vago-vagal circuitry involved in postprandial functions. The Journal of Comparative Neurology. 518: 6-24. PMID 19882715 DOI: 10.1002/cne.22221  0.96
2010 Bonnen PE, Lowe JK, Altshuler DM, Breslow JL, Stoffel M, Friedman JM, Pe'er I. European admixture on the Micronesian island of Kosrae: lessons from complete genetic information. European Journal of Human Genetics : Ejhg. 18: 309-16. PMID 19844264 DOI: 10.1038/ejhg.2009.180  0.96
2010 Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene (DOI:10.1016/j.cmet.2009.11.007) Cell Metabolism. 11: 239. DOI: 10.1016/j.cmet.2010.02.010  0.96
2009 Alon T, Zhou L, Pérez CA, Garfield AS, Friedman JM, Heisler LK. Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. Endocrinology. 150: 5626-32. PMID 19854866 DOI: 10.1210/en.2009-0881  0.96
2009 Elefteriou F, Kolanczyk M, Schindeler A, Viskochil DH, Hock JM, Schorry EK, Crawford AH, Friedman JM, Little D, Peltonen J, Carey JC, Feldman D, Yu X, Armstrong L, Birch P, et al. Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options. American Journal of Medical Genetics. Part A. 149: 2327-38. PMID 19764036 DOI: 10.1002/ajmg.a.33045  0.32
2009 Kenny EE, Gusev A, Riegel K, Lütjohann D, Lowe JK, Salit J, Maller JB, Stoffel M, Daly MJ, Altshuler DM, Friedman JM, Breslow JL, Pe'er I, Sehayek E. Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae. Proceedings of the National Academy of Sciences of the United States of America. 106: 13886-91. PMID 19667188 DOI: 10.1073/pnas.0907336106  0.96
2009 Ceccarini G, Flavell RR, Butelman ER, Synan M, Willnow TE, Bar-Dagan M, Goldsmith SJ, Kreek MJ, Kothari P, Vallabhajosula S, Muir TW, Friedman JM. PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metabolism. 10: 148-59. PMID 19656493 DOI: 10.1016/j.cmet.2009.07.001  0.96
2009 Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G, Schmidt S, Vidal-Puig A, Diano S, Andrews P, Brand MD, Friedman J. Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. Proceedings of the National Academy of Sciences of the United States of America. 106: 13100-5. PMID 19622746 DOI: 10.1073/pnas.0903723106  0.96
2009 Vincent KR, Friedman JM, Griffin ER. Erosional consequence of saltcedar control. Environmental Management. 44: 218-27. PMID 19548024 DOI: 10.1007/s00267-009-9314-8  0.44
2009 Wang W, Huang L, Huang Y, Yin JW, Berk AJ, Friedman JM, Wang G. Mediator MED23 links insulin signaling to the adipogenesis transcription cascade. Developmental Cell. 16: 764-71. PMID 19460352 DOI: 10.1016/j.devcel.2009.04.006  0.96
2009 Friedman JM. Obesity: Causes and control of excess body fat. Nature. 459: 340-2. PMID 19458707 DOI: 10.1038/459340a  0.96
2009 Smith JG, Lowe JK, Kovvali S, Maller JB, Salit J, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Breslow JL, Newton-Cheh C. Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 634-41. PMID 19389651 DOI: 10.1016/j.hrthm.2009.02.022  0.96
2009 Scott MM, Lachey JL, Sternson SM, Lee CE, Elias CF, Friedman JM, Elmquist JK. Leptin targets in the mouse brain. The Journal of Comparative Neurology. 514: 518-32. PMID 19350671 DOI: 10.1002/cne.22025  0.96
2009 Lowe JK, Maller JB, Pe'er I, Neale BM, Salit J, Kenny EE, Shea JL, Burkhardt R, Smith JG, Ji W, Noel M, Foo JN, Blundell ML, Skilling V, Garcia L, ... ... Friedman JM, et al. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. Plos Genetics. 5: e1000365. PMID 19197348 DOI: 10.1371/journal.pgen.1000365  0.96
2009 Friedman JM. Leptin at 14 y of age: an ongoing story. The American Journal of Clinical Nutrition. 89: 973S-979S. PMID 19190071 DOI: 10.3945/ajcn.2008.26788B  0.96
2009 Gusev A, Lowe JK, Stoffel M, Daly MJ, Altshuler D, Breslow JL, Friedman JM, Pe'er I. Whole population, genome-wide mapping of hidden relatedness. Genome Research. 19: 318-26. PMID 18971310 DOI: 10.1101/gr.081398.108  0.96
2008 Rodeheffer MS, Birsoy K, Friedman JM. Identification of white adipocyte progenitor cells in vivo. Cell. 135: 240-9. PMID 18835024 DOI: 10.1016/j.cell.2008.09.036  0.96
2008 Burkhardt R, Kenny EE, Lowe JK, Birkeland A, Josowitz R, Noel M, Salit J, Maller JB, Pe'er I, Daly MJ, Altshuler D, Stoffel M, Friedman JM, Breslow JL. Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2078-84. PMID 18802019 DOI: 10.1161/ATVBAHA.108.172288  0.96
2008 Birsoy K, Soukas A, Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva G, Viale A, Socci ND, Friedman JM. Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12985-90. PMID 18753616 DOI: 10.1073/pnas.0805621105  0.96
2008 Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 454: 846-51. PMID 18668043 DOI: 10.1038/nature07181  0.96
2008 Flavell RR, Kothari P, Bar-Dagan M, Synan M, Vallabhajosula S, Friedman JM, Muir TW, Ceccarini G. Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. Journal of the American Chemical Society. 130: 9106-12. PMID 18570424 DOI: 10.1021/ja801666z  0.96
2008 Zeigerer A, Rodeheffer MS, McGraw TE, Friedman JM. Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism. Experimental Cell Research. 314: 2249-56. PMID 18501893 DOI: 10.1016/j.yexcr.2008.04.003  0.96
2008 Birsoy K, Chen Z, Friedman J. Transcriptional regulation of adipogenesis by KLF4. Cell Metabolism. 7: 339-47. PMID 18396140 DOI: 10.1016/j.cmet.2008.02.001  0.96
2007 Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM. Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. Cell Metabolism. 5: 115-28. PMID 17276354 DOI: 10.1016/j.cmet.2007.01.005  0.96
2007 Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metabolism. 5: 21-33. PMID 17189204 DOI: 10.1016/j.cmet.2006.12.002  0.96
2006 Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, ... ... Friedman JM, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 51: 239-49. PMID 16846858 DOI: 10.1016/j.neuron.2006.06.004  0.96
2006 Shmulewitz D, Heath SC, Blundell ML, Han Z, Sharma R, Salit J, Auerbach SB, Signorini S, Breslow JL, Stoffel M, Friedman JM. Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. Proceedings of the National Academy of Sciences of the United States of America. 103: 3502-9. PMID 16537441 DOI: 10.1073/pnas.0510156103  0.96
2006 Bonnen PE, Pe'er I, Plenge RM, Salit J, Lowe JK, Shapero MH, Lifton RP, Breslow JL, Daly MJ, Reich DE, Jones KW, Stoffel M, Altshuler D, Friedman JM. Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia. Nature Genetics. 38: 214-7. PMID 16429162 DOI: 10.1038/ng1712  0.96
2006 Alon T, Friedman JM. Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 389-97. PMID 16407534 DOI: 10.1523/JNEUROSCI.1203-05.2006  0.96
2005 Sternson SM, Shepherd GM, Friedman JM. Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nature Neuroscience. 8: 1356-63. PMID 16172601 DOI: 10.1038/nn1550  0.96
2005 Chen Z, Torrens JI, Anand A, Spiegelman BM, Friedman JM. Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metabolism. 1: 93-106. PMID 16054051 DOI: 10.1016/j.cmet.2004.12.009  0.96
2005 Li D, Yea S, Li S, Chen Z, Narla G, Banck M, Laborda J, Tan S, Friedman JM, Friedman SL, Walsh MJ. Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. The Journal of Biological Chemistry. 280: 26941-52. PMID 15917248 DOI: 10.1074/jbc.M500463200  0.96
2005 Segal JP, Stallings NR, Lee CE, Zhao L, Socci N, Viale A, Harris TM, Soares MB, Childs G, Elmquist JK, Parker KL, Friedman JM. Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4181-8. PMID 15843621 DOI: 10.1523/JNEUROSCI.0158-05.2005  0.96
2005 Montez JM, Soukas A, Asilmaz E, Fayzikhodjaeva G, Fantuzzi G, Friedman JM. Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 102: 2537-42. PMID 15699332 DOI: 10.1073/pnas.0409530102  0.96
2005 Kishi T, Aschkenasi CJ, Choi BJ, Lopez ME, Lee CE, Liu H, Hollenberg AN, Friedman JM, Elmquist JK. Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. The Journal of Comparative Neurology. 482: 217-43. PMID 15690487 DOI: 10.1002/cne.20432  0.96
2005 Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 146: 2157-64. PMID 15677756 DOI: 10.1210/en.2004-1572  0.96
2005 Cohen P, Yang G, Yu X, Soukas AA, Wolfish CS, Friedman JM, Li C. Induction of leptin receptor expression in the liver by leptin and food deprivation. The Journal of Biological Chemistry. 280: 10034-9. PMID 15644325 DOI: 10.1074/jbc.M413684200  0.96
2005 Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 288: E599-607. PMID 15562249 DOI: 10.1152/ajpendo.00439.2004  0.96
2005 Brown M, Flier J, Friedman J, Goldstein J, Kahn CR, Lifton R, O'Rahilly S, Spiegelman B. Cell Metabolism: Why, and why now? Cell Metabolism. 1: 3. DOI: 10.1016/j.cmet.2004.12.007  0.96
2004 Wolfrum C, Asilmaz E, Luca E, Friedman JM, Stoffel M. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature. 432: 1027-32. PMID 15616563 DOI: 10.1038/nature03047  0.96
2004 Cohen P, Friedman JM. Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). The Journal of Nutrition. 134: 2455S-2463S. PMID 15333742  0.96
2004 Sehayek E, Yu HJ, von Bergmann K, Lutjohann D, Stoffel M, Duncan EM, Garcia-Naveda L, Salit J, Blundell ML, Friedman JM, Breslow JL. Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels. Journal of Lipid Research. 45: 1608-13. PMID 15210841 DOI: 10.1194/jlr.M400006-JLR200  0.96
2004 Friedman JM. Modern science versus the stigma of obesity. Nature Medicine. 10: 563-9. PMID 15170194 DOI: 10.1038/nm0604-563  0.96
2004 Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proceedings of the National Academy of Sciences of the United States of America. 101: 6409-14. PMID 15096593 DOI: 10.1073/pnas.0401627101  0.96
2004 Pinto S, Roseberry AG, Liu H, Diano S, Shanabrough M, Cai X, Friedman JM, Horvath TL. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science (New York, N.Y.). 304: 110-5. PMID 15064421 DOI: 10.1126/science.1089459  0.96
2004 Roseberry AG, Liu H, Jackson AC, Cai X, Friedman JM. Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron. 41: 711-22. PMID 15003171 DOI: 10.1016/S0896-6273(04)00074-1  0.96
2004 Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. The Journal of Clinical Investigation. 113: 414-24. PMID 14755338 DOI: 10.1172/JCI19511  0.96
2003 Cohen P, Ntambi JM, Friedman JM. Stearoyl-CoA desaturase-1 and the metabolic syndrome. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 3: 271-80. PMID 14683458  0.96
2003 Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14531-6. PMID 14581619 DOI: 10.1073/pnas.2235619100  0.96
2003 Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13698-703. PMID 14581612 DOI: 10.1073/pnas.1735416100  0.96
2003 Haqq AM, René P, Kishi T, Khong K, Lee CE, Liu H, Friedman JM, Elmquist JK, Cone RD. Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. The Biochemical Journal. 376: 595-605. PMID 14531729 DOI: 10.1042/BJ20031241  0.96
2003 Ishii M, Fei H, Friedman JM. Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity. Proceedings of the National Academy of Sciences of the United States of America. 100: 10540-5. PMID 12925742 DOI: 10.1073/pnas.1334189100  0.96
2003 Liu H, Kishi T, Roseberry AG, Cai X, Lee CE, Montez JM, Friedman JM, Elmquist JK. Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7143-54. PMID 12904474  0.96
2003 Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM. Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. The Journal of Biological Chemistry. 278: 33904-11. PMID 12815040 DOI: 10.1074/jbc.M304724200  0.96
2003 Alon T, Friedman JM, Socci ND. Cytokine-induced patterns of gene expression in skeletal muscle tissue. The Journal of Biological Chemistry. 278: 32324-34. PMID 12750389 DOI: 10.1074/jbc.M300972200  0.96
2003 Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, Cohen P, Del Prato S, Friedman JM, Maffei M. Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. Journal of Cellular Physiology. 195: 309-21. PMID 12652657 DOI: 10.1002/jcp.10253  0.96
2003 Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, ... Friedman JM, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37: 649-61. PMID 12597862 DOI: 10.1016/S0896-6273(03)00063-1  0.96
2002 Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proceedings of the National Academy of Sciences of the United States of America. 99: 11482-6. PMID 12177411 DOI: 10.1073/pnas.132384699  0.96
2002 Han Z, Heath SC, Shmulewitz D, Li W, Auerbach SB, Blundell ML, Lehner T, Ott J, Stoffel M, Friedman JM, Breslow JL. Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. American Journal of Medical Genetics. 110: 234-42. PMID 12116231 DOI: 10.1002/ajmg.10445  0.96
2002 Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (New York, N.Y.). 297: 240-3. PMID 12114623 DOI: 10.1126/science.1071527  0.96
2002 Chiellini C, Bertacca A, Novelli SE, Görgün CZ, Ciccarone A, Giordano A, Xu H, Soukas A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego L, ... ... Friedman JM, et al. Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. Journal of Cellular Physiology. 190: 251-8. PMID 11807829 DOI: 10.1002/jcp.10061  0.96
2001 Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, Friedman JM. Selective deletion of leptin receptor in neurons leads to obesity. The Journal of Clinical Investigation. 108: 1113-21. PMID 11602618 DOI: 10.1172/JCI13914  0.96
2001 Shmulewitz D, Auerbach SB, Lehner T, Blundell ML, Winick JD, Youngman LD, Skilling V, Heath SC, Ott J, Stoffel M, Breslow JL, Friedman JM. Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Human Heredity. 51: 8-19. PMID 11096265 DOI: 10.1159/000022953  0.96
2000 Soukas A, Cohen P, Socci ND, Friedman JM. Leptin-specific patterns of gene expression in white adipose tissue. Genes & Development. 14: 963-80. PMID 10783168  0.96
1996 Vaisse C, Halaas JL, Horvath CM, Darnell JE, Stoffel M, Friedman JM. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nature Genetics. 14: 95-7. PMID 8782827 DOI: 10.1038/ng0996-95  0.96
1996 Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM. Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379: 632-5. PMID 8628397 DOI: 10.1038/379632a0  0.6
1989 Xanthopoulos KG, Mirkovitch J, Friedman JM, Darnell JE. The mouse Cebp gene encoding a DNA-binding protein is polymorphic and is located on chromosome 7. Cytogenetics and Cell Genetics. 50: 174-5. PMID 2570675  0.96
1987 Babiss LE, Friedman JM, Darnell JE. Cellular promoters incorporated into the adenovirus genome. Effect of viral DNA replication on endogenous and exogenous gene transcription. Journal of Molecular Biology. 193: 643-50. PMID 3612788 DOI: 10.1016/0022-2836(87)90347-0  0.96
1987 Friedman JM, Babiss LE, Weiss M, Darnell JE. Hepatoma variants (C2) are defective for transcriptional and post-transcriptional actions from both endogenous and viral genomes. The Embo Journal. 6: 1727-31. PMID 2956094  0.96
1986 Babiss LE, Bennett A, Friedman JM, Darnell JE. DNase I-hypersensitive sites in the 5'-flanking region of the rat serum albumin gene: correlation between chromatin structure and transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. 83: 6504-8. PMID 3462709  0.96
1986 Babiss LE, Friedman JM, Darnell JE. Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters. Molecular and Cellular Biology. 6: 3798-806. PMID 2948109  0.96
1986 Friedman JM, Babiss LE, Clayton DF, Darnell JE. Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression. Molecular and Cellular Biology. 6: 3791-7. PMID 2948108  0.96
1984 Friedman JM, Chung EY, Darnell JE. Gene expression during liver regeneration. Journal of Molecular Biology. 179: 37-53. PMID 6502711 DOI: 10.1016/0022-2836(84)90305-X  0.96
1984 Powell DJ, Friedman JM, Oulette AJ, Krauter KS, Darnell JE. Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver. Journal of Molecular Biology. 179: 21-35. PMID 6502710 DOI: 10.1016/0022-2836(84)90304-8  0.96
Show low-probability matches.