Guido Reifenberger, M.D. - Publications

Affiliations: 
Department of Neuropathology Heinrich-Heine-University Düsseldorf, Germany 

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Year Citation  Score
2020 Herrera-Rios D, Mughal SS, Teuber-Hanselmann S, Pierscianek D, Sucker A, Jansen P, Schimming T, Klode J, Reifenberger J, Felsberg J, Keyvani K, Brors B, Sure U, Reifenberger G, Schadendorf D, et al. Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain. Frontiers in Immunology. 11: 120. PMID 32117271 DOI: 10.3389/fimmu.2020.00120  0.32
2016 Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathologica. 131: 803-20. PMID 27157931 DOI: 10.1007/s00401-016-1545-1  0.48
2015 Herrlinger U, Jones DT, Glas M, Hattingen E, Gramatzki D, Stuplich M, Felsberg J, Bähr O, Gielen GH, Simon M, Wiewrodt D, Schabet M, Hovestadt V, Capper D, Steinbach JP, ... ... Reifenberger G, et al. Gliomatosis cerebri: no evidence for a separate brain tumor entity. Acta Neuropathologica. PMID 26493382 DOI: 10.1007/s00401-015-1495-z  0.48
2015 Korshunov A, Capper D, Reuss D, Schrimpf D, Ryzhova M, Hovestadt V, Sturm D, Meyer J, Jones C, Zheludkova O, Kumirova E, Golanov A, Kool M, Schüller U, Mittelbronn M, ... ... Reifenberger G, et al. Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity. Acta Neuropathologica. PMID 26482474 DOI: 10.1007/s00401-015-1493-1  0.48
2015 Reuss DE, Kratz A, Sahm F, Capper D, Schrimpf D, Koelsche C, Hovestadt V, Bewerunge-Hudler M, Jones DT, Schittenhelm J, Mittelbronn M, Rushing E, Simon M, Westphal M, Unterberg A, ... ... Reifenberger G, et al. Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathologica. PMID 26087904 DOI: 10.1007/s00401-015-1454-8  0.48
2015 Weller M, Weber RG, Willscher E, Riehmer V, Hentschel B, Kreuz M, Felsberg J, Beyer U, Löffler-Wirth H, Kaulich K, Steinbach JP, Hartmann C, Gramatzki D, Schramm J, Westphal M, ... ... Reifenberger G, et al. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups. Acta Neuropathologica. 129: 679-93. PMID 25783747 DOI: 10.1007/s00401-015-1409-0  0.48
2015 Korshunov A, Ryzhova M, Hovestadt V, Bender S, Sturm D, Capper D, Meyer J, Schrimpf D, Kool M, Northcott PA, Zheludkova O, Milde T, Witt O, Kulozik AE, Reifenberger G, et al. Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers. Acta Neuropathologica. 129: 669-78. PMID 25752754 DOI: 10.1007/s00401-015-1405-4  0.48
2015 Weller M, Tabatabai G, Kästner B, Felsberg J, Steinbach JP, Wick A, Schnell O, Hau P, Herrlinger U, Sabel MC, Wirsching HG, Ketter R, Bähr O, Platten M, Tonn JC, ... ... Reifenberger G, et al. MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2057-64. PMID 25655102 DOI: 10.1158/1078-0432.CCR-14-2737  0.48
2015 Dunkl V, Cleff C, Stoffels G, Judov N, Sarikaya-Seiwert S, Law I, Bøgeskov L, Nysom K, Andersen SB, Steiger HJ, Fink GR, Reifenberger G, Shah NJ, Coenen HH, Langen KJ, et al. The usefulness of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the clinical evaluation of brain tumors in children and adolescents. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 88-92. PMID 25525183 DOI: 10.2967/jnumed.114.148734  0.48
2015 Galldiks N, Dunkl V, Stoffels G, Hutterer M, Rapp M, Sabel M, Reifenberger G, Kebir S, Dorn F, Blau T, Herrlinger U, Hau P, Ruge MI, Kocher M, Goldbrunner R, et al. Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET. European Journal of Nuclear Medicine and Molecular Imaging. 42: 685-95. PMID 25411133 DOI: 10.1007/s00259-014-2959-4  0.48
2015 Röck K, Tigges J, Sass S, Schütze A, Florea AM, Fender AC, Theis FJ, Krutmann J, Boege F, Fritsche E, Reifenberger G, Fischer JW. miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging. The Journal of Investigative Dermatology. 135: 369-77. PMID 25264594 DOI: 10.1038/jid.2014.422  0.48
2014 Waldera-Lupa DM, Kalfalah F, Florea AM, Sass S, Kruse F, Rieder V, Tigges J, Fritsche E, Krutmann J, Busch H, Boerries M, Meyer HE, Boege F, Theis F, Reifenberger G, et al. Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts. Aging. 6: 856-78. PMID 25411231  0.48
2014 Codo P, Weller M, Meister G, Szabo E, Steinle A, Wolter M, Reifenberger G, Roth P. MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape. Oncotarget. 5: 7651-62. PMID 25277195  0.48
2014 Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, ... ... Reifenberger G, et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature. 511: 428-34. PMID 25043047 DOI: 10.1038/nature13379  0.48
2014 Wiestler B, Capper D, Hovestadt V, Sill M, Jones DT, Hartmann C, Felsberg J, Platten M, Feiden W, Keyvani K, Pfister SM, Wiestler OD, Meyermann R, Reifenberger G, Pietsch T, et al. Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. Neuro-Oncology. 16: 1630-8. PMID 25028501 DOI: 10.1093/neuonc/nou138  0.48
2014 Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, ... ... Reifenberger G, et al. Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. Acta Neuropathologica. 128: 561-71. PMID 25008768 DOI: 10.1007/s00401-014-1315-x  0.48
2014 Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, et al. International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathology (Zurich, Switzerland). 24: 429-35. PMID 24990071 DOI: 10.1111/bpa.12171  0.48
2014 Wick W, Weller M, van den Bent M, Sanson M, Weiler M, von Deimling A, Plass C, Hegi M, Platten M, Reifenberger G. MGMT testing--the challenges for biomarker-based glioma treatment. Nature Reviews. Neurology. 10: 372-85. PMID 24912512 DOI: 10.1038/nrneurol.2014.100  0.48
2014 Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northcott PA, Sultan M, Stachurski K, Ryzhova M, Warnatz HJ, Ralser M, Brun S, Bunt J, Jäger N, Kleinheinz K, ... ... Reifenberger G, et al. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature. 510: 537-41. PMID 24847876 DOI: 10.1038/nature13268  0.48
2014 Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones DT, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott PA, von Hoff K, von Bueren AO, Friedrich C, Mynarek M, ... ... Reifenberger G, et al. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort. Acta Neuropathologica. 128: 137-49. PMID 24791927 DOI: 10.1007/s00401-014-1276-0  0.48
2014 Riehmer V, Gietzelt J, Beyer U, Hentschel B, Westphal M, Schackert G, Sabel MC, Radlwimmer B, Pietsch T, Reifenberger G, Weller M, Weber RG, Loeffler M. Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma. Genes, Chromosomes & Cancer. 53: 589-605. PMID 24706357 DOI: 10.1002/gcc.22169  0.48
2014 Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V, Piro RM, Esparza LA, Markant SL, Remke M, Milde T, Bourdeaut F, Ryzhova M, Sturm D, Pfaff E, ... ... Reifenberger G, et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell. 25: 393-405. PMID 24651015 DOI: 10.1016/j.ccr.2014.02.004  0.48
2014 Reifenberger G, Weber RG, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel MC, Gramatzki D, et al. Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling. International Journal of Cancer. Journal International Du Cancer. 135: 1822-31. PMID 24615357 DOI: 10.1002/ijc.28836  0.48
2014 Weller M, Kaulich K, Hentschel B, Felsberg J, Gramatzki D, Pietsch T, Simon M, Westphal M, Schackert G, Tonn JC, von Deimling A, Davis T, Weiss WA, Loeffler M, Reifenberger G, et al. Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy. International Journal of Cancer. Journal International Du Cancer. 134: 2437-47. PMID 24614983 DOI: 10.1002/ijc.28576  0.48
2013 Galldiks N, Stoffels G, Ruge MI, Rapp M, Sabel M, Reifenberger G, Erdem Z, Shah NJ, Fink GR, Coenen HH, Langen KJ. Role of O-(2-18F-fluoroethyl)-L-tyrosine PET as a diagnostic tool for detection of malignant progression in patients with low-grade glioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 2046-54. PMID 24159047 DOI: 10.2967/jnumed.113.123836  0.48
2013 Wick W, Meisner C, Hentschel B, Platten M, Schilling A, Wiestler B, Sabel MC, Koeppen S, Ketter R, Weiler M, Tabatabai G, von Deimling A, Gramatzki D, Westphal M, Schackert G, ... ... Reifenberger G, et al. Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation. Neurology. 81: 1515-22. PMID 24068788 DOI: 10.1212/WNL.0b013e3182a95680  0.48
2013 Hartmann C, Hentschel B, Simon M, Westphal M, Schackert G, Tonn JC, Loeffler M, Reifenberger G, Pietsch T, von Deimling A, Weller M. Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5146-57. PMID 23918605 DOI: 10.1158/1078-0432.CCR-13-0017  0.48
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, ... ... Reifenberger G, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics. 45: 927-32. PMID 23817572 DOI: 10.1038/ng.2682  0.48
2013 Tönjes M, Barbus S, Park YJ, Wang W, Schlotter M, Lindroth AM, Pleier SV, Bai AH, Karra D, Piro RM, Felsberg J, Addington A, Lemke D, Weibrecht I, Hovestadt V, ... ... Reifenberger G, et al. BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1. Nature Medicine. 19: 901-8. PMID 23793099 DOI: 10.1038/nm.3217  0.48
2013 Hovestadt V, Remke M, Kool M, Pietsch T, Northcott PA, Fischer R, Cavalli FM, Ramaswamy V, Zapatka M, Reifenberger G, Rutkowski S, Schick M, Bewerunge-Hudler M, Korshunov A, Lichter P, et al. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays. Acta Neuropathologica. 125: 913-6. PMID 23670100 DOI: 10.1007/s00401-013-1126-5  0.48
2013 Wiestler B, Claus R, Hartlieb SA, Schliesser MG, Weiss EK, Hielscher T, Platten M, Dittmann LM, Meisner C, Felsberg J, Happold C, Simon M, Nikkhah G, Papsdorf K, Steinbach JP, ... ... Reifenberger G, et al. Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective. Neuro-Oncology. 15: 1017-26. PMID 23595628 DOI: 10.1093/neuonc/not043  0.48
2012 Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, ... ... Reifenberger G, et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 22: 425-37. PMID 23079654 DOI: 10.1016/j.ccr.2012.08.024  0.48
2012 Liu XY, Gerges N, Korshunov A, Sabha N, Khuong-Quang DA, Fontebasso AM, Fleming A, Hadjadj D, Schwartzentruber J, Majewski J, Dong Z, Siegel P, Albrecht S, Croul S, Jones DT, ... ... Reifenberger G, et al. Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathologica. 124: 615-25. PMID 22886134 DOI: 10.1007/s00401-012-1031-3  0.48
2012 Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, ... ... Reifenberger G, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature. 488: 100-5. PMID 22832583 DOI: 10.1038/nature11284  0.48
2012 von dem Knesebeck A, Felsberg J, Waha A, Hartmann W, Scheffler B, Glas M, Hammes J, Mikeska T, Yan PS, Endl E, Simon M, Reifenberger G, Pietsch T, Waha A. RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. Neoplasia (New York, N.Y.). 14: 526-34. PMID 22787434 DOI: 10.1596/neo.12360  0.48
2012 Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, ... Reifenberger G, et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature. 488: 656-9. PMID 22763442 DOI: 10.1038/nature11323  0.48
2012 Wick W, Platten M, Meisner C, Felsberg J, Tabatabai G, Simon M, Nikkhah G, Papsdorf K, Steinbach JP, Sabel M, Combs SE, Vesper J, Braun C, Meixensberger J, Ketter R, ... ... Reifenberger G, et al. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. The Lancet. Oncology. 13: 707-15. PMID 22578793 DOI: 10.1016/S1470-2045(12)70164-X  0.48
2012 Haag D, Zipper P, Westrich V, Karra D, Pfleger K, Toedt G, Blond F, Delhomme N, Hahn M, Reifenberger J, Reifenberger G, Lichter P. Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration. Plos Genetics. 8: e1002572. PMID 22438824 DOI: 10.1371/journal.pgen.1002572  0.32
2012 Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, ... ... Reifenberger G, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 482: 226-31. PMID 22286061 DOI: 10.1038/nature10833  0.48
2012 Augustin I, Goidts V, Bongers A, Kerr G, Vollert G, Radlwimmer B, Hartmann C, Herold-Mende C, Reifenberger G, von Deimling A, Boutros M. The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis. Embo Molecular Medicine. 4: 38-51. PMID 22147553 DOI: 10.1002/emmm.201100186  0.48
2012 Reifenberger G, Hentschel B, Felsberg J, Schackert G, Simon M, Schnell O, Westphal M, Wick W, Pietsch T, Loeffler M, Weller M. Predictive impact of MGMT promoter methylation in glioblastoma of the elderly. International Journal of Cancer. Journal International Du Cancer. 131: 1342-50. PMID 22139906 DOI: 10.1002/ijc.27385  0.48
2011 Lindemann C, Hackmann O, Delic S, Schmidt N, Reifenberger G, Riemenschneider MJ. SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation Acta Neuropathologica. 122: 241-251. PMID 21590492 DOI: 10.1007/s00401-011-0832-0  0.48
2011 Hartmann C, Hentschel B, Tatagiba M, Schramm J, Schnell O, Seidel C, Stein R, Reifenberger G, Pietsch T, von Deimling A, Loeffler M, Weller M. Molecular markers in low-grade gliomas: predictive or prognostic? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4588-99. PMID 21558404 DOI: 10.1158/1078-0432.CCR-10-3194  0.48
2011 Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, Westphal M, Schackert G, Kreth FW, Pietsch T, Löffler M, Weller M, Reifenberger G, Tonn JC. Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. International Journal of Cancer. Journal International Du Cancer. 129: 659-70. PMID 21425258 DOI: 10.1002/ijc.26083  0.48
2011 Kim Y, Reifenberger G, Lu D, Endo T, Carson DA, Gast SM, Meschenmoser K, Nowak M, Schmidt-Wolf IG. Influencing the Wnt signaling pathway in multiple myeloma. Anticancer Research. 31: 725-30. PMID 21378363  0.48
2011 Barbus S, Tews B, Karra D, Hahn M, Radlwimmer B, Delhomme N, Hartmann C, Felsberg J, Krex D, Schackert G, Martinez R, Reifenberger G, Lichter P. Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors. Journal of the National Cancer Institute. 103: 598-606. PMID 21346226 DOI: 10.1093/jnci/djr036  0.48
2011 Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister S, Hartmann C, Paulus W, ... Reifenberger G, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathologica. 121: 397-405. PMID 21274720 DOI: 10.1007/s00401-011-0802-6  0.48
2011 Toedt G, Barbus S, Wolter M, Felsberg J, Tews B, Blond F, Sabel MC, Hofmann S, Becker N, Hartmann C, Ohgaki H, von Deimling A, Wiestler OD, Hahn M, Lichter P, ... Reifenberger G, et al. Molecular signatures classify astrocytic gliomas by IDH1 mutation status. International Journal of Cancer. Journal International Du Cancer. 128: 1095-103. PMID 20473936 DOI: 10.1002/ijc.25448  0.48
2010 Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A. Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathologica. 120: 707-18. PMID 21088844 DOI: 10.1007/s00401-010-0781-z  0.48
2010 Reifenberger G, Wesseling P. Molecular diagnostics of brain tumors. Acta Neuropathologica. 120: 549-51. PMID 20927631 DOI: 10.1007/s00401-010-0752-4  0.48
2010 Traenka C, Remke M, Korshunov A, Bender S, Hielscher T, Northcott PA, Witt H, Ryzhova M, Felsberg J, Benner A, Riester S, Scheurlen W, Grunewald TG, von Deimling A, Kulozik AE, ... Reifenberger G, et al. Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. Cancer Research. 70: 8003-14. PMID 20924110 DOI: 10.1158/0008-5472.CAN-10-0592  0.48
2010 Riemenschneider MJ, Jeuken JW, Wesseling P, Reifenberger G. Molecular diagnostics of gliomas: state of the art. Acta Neuropathologica. 120: 567-84. PMID 20714900 DOI: 10.1007/s00401-010-0736-4  0.48
2010 Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain : a Journal of Neurology. 133: 983-95. PMID 20375133 DOI: 10.1093/brain/awq042  0.48
2010 Liu HK, Wang Y, Belz T, Bock D, Takacs A, Radlwimmer B, Barbus S, Reifenberger G, Lichter P, Schütz G. The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes & Development. 24: 683-95. PMID 20360385 DOI: 10.1101/gad.560310  0.48
2010 Waha A, Felsberg J, Hartmann W, von dem Knesebeck A, Mikeska T, Joos S, Wolter M, Koch A, Yan PS, Endl E, Wiestler OD, Reifenberger G, Pietsch T, Waha A. Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. Cancer Research. 70: 1689-99. PMID 20124482 DOI: 10.1158/0008-5472.CAN-09-3218  0.48
2010 Küsters-Vandevelde HV, Klaasen A, Küsters B, Groenen PJ, van Engen-van Grunsven IA, van Dijk MR, Reifenberger G, Wesseling P, Blokx WA. Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system. Acta Neuropathologica. 119: 317-23. PMID 19936769 DOI: 10.1007/s00401-009-0611-3  0.48
2009 Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, Sabel MC, Koeppen S, Ketter R, Meyermann R, Rapp M, Meisner C, Kortmann RD, Pietsch T, Wiestler OD, ... ... Reifenberger G, et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5874-80. PMID 19901110 DOI: 10.1200/JCO.2009.23.6497  0.48
2006 Schneider DT, Zahn S, Sievers S, Alemazkour K, Reifenberger G, Wiestler OD, Calaminus G, Göbel U, Perlman EJ. Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 864-73. PMID 16607373 DOI: 10.1038/modpathol.3800607  0.48
1996 Reifenberger J, Ring GU, Gies U, Cobbers L, Oberstrass J, An HX, Niederacher D, Wechsler W, Reifenberger G. Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. Journal of Neuropathology and Experimental Neurology. 55: 822-31. PMID 8965097  0.48
1996 Reifenberger G, Boström J, Bettag M, Bock WJ, Wechsler W, Kepes JJ. Primary glioblastoma multiforme of the oculomotor nerve. Case report. Journal of Neurosurgery. 84: 1062-6. PMID 8847574 DOI: 10.3171/jns.1996.84.6.1062  0.48
1996 Oberstrass J, Reifenberger G, Reifenberger J, Wechsler W, Collins VP. Mutation of the Von Hippel-Lindau tumour suppressor gene in capillary haemangioblastomas of the central nervous system. The Journal of Pathology. 179: 151-6. PMID 8758206 DOI: 10.1002/(SICI)1096-9896(199606)179:2<151::AID-PATH556>3.0.CO;2-0  0.48
1996 Reifenberger J, Reifenberger G, Ichimura K, Schmidt EE, Wechsler W, Collins VP. Epidermal growth factor receptor expression in oligodendroglial tumors. The American Journal of Pathology. 149: 29-35. PMID 8686753  0.48
1995 Schober R, Bilzer T, Waha A, Reifenberger G, Wechsler W, von Deimling A, Wiestler OD, Westphal M, Kemshead JT, Vega F. The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial. Clinical Neuropathology. 14: 169-74. PMID 7671460  0.48
1995 Reifenberger G, Reifenberger J, Bilzer T, Wechsler W, Collins VP. Coexpression of transforming growth factor-alpha and épidermal growth factor receptor in capillary hemangioblastomas of the central nervous system. The American Journal of Pathology. 147: 245-50. PMID 7639324  0.48
1994 Westphal M, Hamel W, Zirkel D, Herrmann HD, Bilzer T, Reifenberger G, Schober R, Wechsler W, Albert FK, Behnke J. Epidermal growth factor receptor expression in human malignant glioma: in vitro and in vivo effects of application of monoclonal antibodies to the epidermal growth factor receptor. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 135: 171-84. PMID 8047692  0.48
1994 Reifenberger J, Reifenberger G, Liu L, James CD, Wechsler W, Collins VP. Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. The American Journal of Pathology. 145: 1175-90. PMID 7977648  0.48
1992 Figge C, Reifenberger G, Vogeley KT, Messing M, Roosen N, Wechsler W. Immunohistochemical demonstration of proliferating cell nuclear antigen in glioblastomas: pronounced heterogeneity and lack of prognostic significance. Journal of Cancer Research and Clinical Oncology. 118: 289-95. PMID 1374410 DOI: 10.1007/BF01208618  0.48
1992 Reifenberger G, Sieth P, Niederhaus M, Wechsler W. Expression of CD15 in tumours of the nervous system. The Histochemical Journal. 24: 890-901. PMID 1362199 DOI: 10.1007/BF01046360  0.48
1991 Vogeley KT, Bilzer T, Reifenberger G, Wechsler W. Immunochemistry of ethylnitrosourea-induced rat neurinomas, the RN6 neurinoma cell line and their transplantation tumors. Acta Neuropathologica. 82: 78-85. PMID 1719740 DOI: 10.1007/BF00310927  0.48
1990 Tajika Y, Reifenberger G, Kiwit JC, Wechsler W. Metastatic adenocarcinoma in cerebral astrocytoma: clinicopathological and immunohistochemical study with review of the literature. Acta Neurochirurgica. 105: 50-5. PMID 2239381 DOI: 10.1007/BF01664858  0.48
1990 Prior R, Reifenberger G, Wechsler W. Transferrin receptor expression in tumours of the human nervous system: relation to tumour type, grading and tumour growth fraction. Virchows Archiv. a, Pathological Anatomy and Histopathology. 416: 491-6. PMID 2110696 DOI: 10.1007/BF01600299  0.48
1990 Cardesa A, Ribalta T, Vogeley KT, Reifenberger G, Wechsler W, Turusov VS. Pathology of tumours in laboratory animals. Tumours of the rat. Tumours of the peripheral nervous system. Iarc Scientific Publications. 699-724. PMID 2093667  0.48
1990 Sugita Y, Kepes JJ, Shigemori M, Kuramoto S, Reifenberger G, Kiwit JC, Wechsler W. Pleomorphic xanthoastrocytoma with desmoplastic reaction: angiomatous variant. Report of two cases. Clinical Neuropathology. 9: 271-8. PMID 1962743  0.48
1989 Reifenberger G, Deckert M, Wechsler W. Immunohistochemical determination of protein kinase C expression and proliferative activity in human brain tumors. Acta Neuropathologica. 78: 166-75. PMID 2750486 DOI: 10.1007/BF00688205  0.48
1989 Deckert M, Reifenberger G, Wechsler W. Determination of the proliferative potential of human brain tumors using the monoclonal antibody Ki-67. Journal of Cancer Research and Clinical Oncology. 115: 179-88. PMID 2715168 DOI: 10.1007/BF00397921  0.48
1989 Bilzer T, Reifenberger G, Wechsler W. Chemical induction of brain tumors in rats by nitrosoureas: molecular biology and neuropathology. Neurotoxicology and Teratology. 11: 551-6. PMID 2696875 DOI: 10.1016/0892-0362(89)90036-6  0.48
1989 Reifenberger G, Prior R, Deckert M, Wechsler W. Epidermal growth factor receptor expression and growth fraction in human tumours of the nervous system. Virchows Archiv. a, Pathological Anatomy and Histopathology. 414: 147-55. PMID 2563600 DOI: 10.1007/BF00718594  0.48
1989 Prior R, Reifenberger G, Wechsler W. Nerve growth factor receptor in tumours of the human nervous system. Immunohistochemical analysis of receptor expression and tumour growth fraction. Pathology, Research and Practice. 185: 332-8. PMID 2478988 DOI: 10.1016/S0344-0338(89)80008-1  0.48
1989 Reifenberger G, Bilzer T, Seitz RJ, Wechsler W. Expression of vimentin and glial fibrillary acidic protein in ethylnitrosourea-induced rat gliomas and glioma cell lines. Acta Neuropathologica. 78: 270-82. PMID 2475009 DOI: 10.1007/BF00687757  0.48
1987 Szymas J, Reifenberger G, Wechsler W. Leu-M1 immunoreactivity in the human brain. Discrimination between different tumors and between neoplastic and brain tissue. Die Naturwissenschaften. 74: 188-90. PMID 3600813 DOI: 10.1007/BF00372924  0.48
1987 Reifenberger G, Szymas J, Wechsler W. Differential expression of glial- and neuronal-associated antigens in human tumors of the central and peripheral nervous system. Acta Neuropathologica. 74: 105-23. PMID 3314309 DOI: 10.1007/BF00692841  0.48
1987 Reifenberger G, Mai JK, Krajewski S, Wechsler W. Distribution of anti-Leu-7, anti-Leu-11a and anti-Leu-M1 immunoreactivity in the brain of the adult rat. Cell and Tissue Research. 248: 305-13. PMID 2438044 DOI: 10.1007/BF00218197  0.48
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