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Nagasuma Chandra - Publications

Affiliations: 
Indian Institute of Science, Bengaluru, Karnataka, India 
Area:
Systems Biology, Structural Bioinformatics , Cell Modelling , Computational Immunology, Sequence Analysis, Carbohydrate Recognition
Website:
http://proline.physics.iisc.ernet.in/home/Main_Page
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ravichandran S, Chandra N. Interrogation of genome-wide networks in biology: comparison of knowledge-based and statistical methods International Journal of Advances in Engineering Sciences and Applied Mathematics. 11: 119-137. DOI: 10.1007/S12572-018-0242-9  0.307
2018 Bhagavat R, Sankar S, Srinivasan N, Chandra N. An Augmented Pocketome: Detection and Analysis of Small-Molecule Binding Pockets in Proteins of Known 3D Structure. Structure (London, England : 1993). 26: 499-512.e2. PMID 29514079 DOI: 10.1016/J.Str.2018.02.001  0.342
2018 Gopalan A, Bhagavat R, Chandra N, Subbarao SH, Raja A, Bethunaickan R. Biophysical and biochemical characterization of Rv3405c, a tetracycline repressor protein from Mycobacterium tuberculosis. Biochemical and Biophysical Research Communications. 496: 799-805. PMID 29395080 DOI: 10.1016/J.Bbrc.2018.01.152  0.368
2017 Bhagavat R, Kim HB, Kim CY, Terwilliger TC, Mehta D, Srinivasan N, Chandra N. A genome-wide structure-based survey of nucleotide binding proteins in M. tuberculosis. Scientific Reports. 7: 12489. PMID 28970579 DOI: 10.1038/S41598-017-12471-8  0.375
2017 Ramakrishnan G, Chandra N, Srinivasan N. Exploring anti-malarial potential of FDA approved drugs: an in silico approach. Malaria Journal. 16: 290. PMID 28720135 DOI: 10.1186/S12936-017-1937-2  0.305
2017 Bhaskarla C, Bhosale M, Banerjee P, Chandra N, Nandi D. Protein tagging, destruction and infection. Current Protein & Peptide Science. PMID 28707598 DOI: 10.2174/1389203718666170713100627  0.314
2017 Bhagavat R, Srinivasan N, Chandra N. Deciphering common recognition principles of nucleoside mono/di/and tri-phosphates binding in diverse proteins via structural matching of their binding sites. Proteins. PMID 28547747 DOI: 10.1002/Prot.25328  0.321
2017 Mudgal R, Srinivasan N, Chandra N. Resolving protein structure-function-binding site relationships from a binding site similarity network perspective. Proteins. PMID 28342236 DOI: 10.1002/Prot.25293  0.338
2016 Gilbert HJ, Chandra N. Editorial overview: Carbohydrate-protein interactions and glycosylation: integrating structural biology, informatics and systems modelling to understand glycan structure and glycan-protein interactions. Current Opinion in Structural Biology. PMID 27899244 DOI: 10.1016/J.Sbi.2016.11.009  0.307
2016 Padiadpu J, Baloni P, Anand K, Munshi M, Thakur C, Mohan A, Singh A, Chandra N. Identifying and Tackling Emergent Vulnerability in Drug-Resistant Mycobacteria. Acs Infectious Diseases. 2: 592-607. PMID 27759382 DOI: 10.1021/Acsinfecdis.6B00004  0.318
2016 Sambaturu N, Mishra M, Chandra N. EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks. Bmc Genomics. 17: 543. PMID 27556637 DOI: 10.1186/S12864-016-2792-1  0.301
2016 Singh A, Bhagavat R, Vijayan M, Chandra N. A comparative analysis of the DNA recombination repair pathway in mycobacterial genomes. Tuberculosis (Edinburgh, Scotland). 99: 109-19. PMID 27450012 DOI: 10.1016/J.Tube.2016.04.011  0.346
2016 Ramakrishnan G, Jain A, Chandra N, Srinivasan N. Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria. Biology Direct. 11: 27. PMID 27246835 DOI: 10.1186/S13062-016-0130-9  0.328
2016 Marathe SA, Balakrishnan A, Negi VD, Sakorey D, Chandra N, Chakravortty D. Curcumin Reduces the Motility of Salmonella enterica serovar Typhimurium by Binding to the Flagella thereby Leading to Flagellar Fragility and Shedding. Journal of Bacteriology. PMID 27091154 DOI: 10.1128/Jb.00092-16  0.314
2016 Padiadpu J, Mishra M, Sharma E, Mala U, Somasundaram K, Chandra N. Probing the druggability limits for enzymes of the NAD biosynthetic network in glioma. Journal of Chemical Information and Modeling. PMID 26958865 DOI: 10.1021/Acs.Jcim.5B00733  0.304
2016 Bhosle A, Chandra N. Structural analysis of dihydrofolate reductases enables rationalization of antifolate binding affinities and suggests repurposing possibilities. The Febs Journal. PMID 26797763 DOI: 10.1111/Febs.13662  0.346
2015 Mudgal R, Sandhya S, Chandra N, Srinivasan N. De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods. Biology Direct. 10: 38. PMID 26228684 DOI: 10.1186/S13062-015-0069-2  0.309
2015 Sharadamma N, Harshavardhana Y, Ravishankar A, Anand P, Chandra N, Muniyappa K. Molecular Dissection of Mycobacterium tuberculosis Integration Host Factor Reveals Novel Insights into the Mode of DNA Binding and Nucleoid Compaction. Biochemistry. 54: 4142-60. PMID 26067376 DOI: 10.1021/Acs.Biochem.5B00447  0.317
2015 Dighe A, Chandra N, Vishveshwara S, Ananthasuresh G. Dissecting Ligand Binding Sites : A Layer at a Time Biophysical Journal. 108: 216a. DOI: 10.1016/J.Bpj.2014.11.1195  0.326
2014 Chandra N, Sandhya S, Anand P. Structural Annotation of the Mycobacterium tuberculosis Proteome. Microbiology Spectrum. 2. PMID 26105824 DOI: 10.1128/Microbiolspec.Mgm2-0027-2013  0.375
2014 Anand P, Nagarajan D, Mukherjee S, Chandra N. ABS-Scan: In silico alanine scanning mutagenesis for binding site residues in protein-ligand complex. F1000research. 3: 214. PMID 25685322 DOI: 10.12688/F1000Research.5165.2  0.327
2014 Anand P, Chandra N. Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection. Scientific Reports. 4: 6356. PMID 25220818 DOI: 10.1038/Srep06356  0.375
2014 Bhagavat R, Chandra N. Common recognition principles across diverse sequence and structural families of sialic acid binding proteins. Glycobiology. 24: 5-16. PMID 24043392 DOI: 10.1093/Glycob/Cwt063  0.35
2013 Sambarey A, Prashanthi K, Chandra N. Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection. Scientific Reports. 3: 2302. PMID 23892477 DOI: 10.1038/Srep02302  0.324
2013 Chandra N, Padiadpu J. Network approaches to drug discovery. Expert Opinion On Drug Discovery. 8: 7-20. PMID 23140510 DOI: 10.1517/17460441.2013.741119  0.336
2013 Padiadpu J, Mukherjee S, Chandra N. Rationalization and prediction of drug resistant mutations in targets for clinical anti-tubercular drugs. Journal of Biomolecular Structure & Dynamics. 31: 44-58. PMID 22803837 DOI: 10.1080/07391102.2012.691361  0.336
2012 Mishra S, Bhagavat R, Chandra N, Vijayarangan N, Rajeswari H, Ajitkumar P. Cloning, expression, purification, and biochemical characterisation of the FIC motif containing protein of Mycobacterium tuberculosis. Protein Expression and Purification. 86: 58-67. PMID 22982230 DOI: 10.1016/J.Pep.2012.08.020  0.336
2012 Vashisht R, Mondal AK, Jain A, Shah A, Vishnoi P, Priyadarshini P, Bhattacharyya K, Rohira H, Bhat AG, Passi A, Mukherjee K, Choudhary KS, Kumar V, Arora A, Munusamy P, ... ... Chandra N, et al. Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis. Plos One. 7: e39808. PMID 22808064 DOI: 10.1371/Journal.Pone.0039808  0.375
2012 Vashisht R, Mondal AK, Jain A, Shah A, Vishnoi P, Priyadarshini P, Bhattacharyya K, Rohira H, Bhat AG, Passi A, Mukherjee K, Choudhary KS, Kumar V, Arora A, Munusamy P, ... ... Chandra N, et al. Illustrates the comprehensive analyses of central proteins as potential drug targets. Plos One. DOI: 10.1371/Journal.Pone.0039808.G004  0.324
2011 Anand P, Sankaran S, Mukherjee S, Yeturu K, Laskowski R, Bhardwaj A, Bhagavat R, Brahmachari SK, Chandra N. Structural annotation of Mycobacterium tuberculosis proteome. Plos One. 6: e27044. PMID 22073123 DOI: 10.1371/Journal.Pone.0027044  0.364
2011 Ghosh S, Prasad KV, Vishveshwara S, Chandra N. Rule-based modelling of iron homeostasis in tuberculosis. Molecular Biosystems. 7: 2750-68. PMID 21833436 DOI: 10.1039/C1Mb05093A  0.301
2011 Chandra N, Kumar D, Rao K. Systems biology of tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: 487-96. PMID 21459043 DOI: 10.1016/J.Tube.2011.02.008  0.353
2011 Anand P, Chandra N. Identification of secondary targets for clinically used anti-tubercular drugs through binding site similarities F1000research. 2. DOI: 10.7490/F1000Research.2120.1  0.308
2010 Padiadpu J, Vashisht R, Chandra N. Protein-protein interaction networks suggest different targets have different propensities for triggering drug resistance. Systems and Synthetic Biology. 4: 311-22. PMID 22132058 DOI: 10.1007/S11693-011-9076-5  0.369
2010 Bhat AG, Vashisht R, Chandra N. Modeling metabolic adjustment in Mycobacterium tuberculosis upon treatment with isoniazid. Systems and Synthetic Biology. 4: 299-309. PMID 22132057 DOI: 10.1007/S11693-011-9075-6  0.31
2010 Chandra N, Anand P, Yeturu K. Structural bioinformatics: deriving biological insights from protein structures. Interdisciplinary Sciences, Computational Life Sciences. 2: 347-66. PMID 21153779 DOI: 10.1007/S12539-010-0045-6  0.332
2010 Raman K, Bhat AG, Chandra N. A systems perspective of host-pathogen interactions: predicting disease outcome in tuberculosis. Molecular Biosystems. 6: 516-30. PMID 20174680 DOI: 10.1039/B912129C  0.31
2009 Chandra N. Computational systems approach for drug target discovery. Expert Opinion On Drug Discovery. 4: 1221-36. PMID 23480463 DOI: 10.1517/17460440903380422  0.312
2009 Raman K, Vashisht R, Chandra N. Strategies for efficient disruption of metabolism in Mycobacterium tuberculosis from network analysis. Molecular Biosystems. 5: 1740-51. PMID 19593474 DOI: 10.1039/B905817F  0.328
2009 Ramaswamy K, Sadiq M, Sridhar, Chandra N. Support Vector Machine Classifier for Predicting Drug Binding to P-glycoprotein Journal of Proteomics & Bioinformatics. 2: 193-201. DOI: 10.4172/Jpb.1000077  0.314
2008 Raman K, Chandra N. Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance. Bmc Microbiology. 8: 234. PMID 19105810 DOI: 10.1186/1471-2180-8-234  0.356
2008 Yeturu K, Chandra N. PocketMatch: a new algorithm to compare binding sites in protein structures. Bmc Bioinformatics. 9: 543. PMID 19091072 DOI: 10.1186/1471-2105-9-543  0.325
2008 Kalidas Y, Chandra N. PocketDepth: a new depth based algorithm for identification of ligand binding sites in proteins. Journal of Structural Biology. 161: 31-42. PMID 17949996 DOI: 10.1016/J.Jsb.2007.09.005  0.313
2008 Raman K, Chandra N. M. tuberculosis interactome analysis unravels potential pathways to drug resistance Nature Precedings. 3: 1-1. DOI: 10.1038/Npre.2008.1674.1  0.333
2007 Singh DD, Chandran D, Jeyakani J, Chandra N. Scanning the genome of Mycobacterium tuberculosis to identify potential lectins. Protein and Peptide Letters. 14: 683-91. PMID 17897094 DOI: 10.2174/092986607781483813  0.349
2007 Raman K, Rajagopalan P, Chandra N. Hallmarks of mycolic acid biosynthesis: a comparative genomics study. Proteins. 69: 358-68. PMID 17600834 DOI: 10.1002/Prot.21591  0.324
2006 Vinod PK, Konkimalla B, Chandra N. In-silico pharmacodynamics: correlation of adverse effects of H2-antihistamines with histamine N-methyl transferase binding potential. Applied Bioinformatics. 5: 141-50. PMID 16922595 DOI: 10.2165/00822942-200605030-00002  0.304
2004 Prasad T, Subramanian T, Hariharaputran S, Chaitra HS, Chandra N. Extracting hydrogen-bond signature patterns from protein structure data. Applied Bioinformatics. 3: 125-35. PMID 15693738 DOI: 10.2165/00822942-200403020-00007  0.34
2003 Konkimalla VB, Chandra N. Determinants of histamine recognition: implications for the design of antihistamines. Biochemical and Biophysical Research Communications. 309: 425-31. PMID 12951067 DOI: 10.1016/J.Bbrc.2003.08.023  0.343
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