David N. Furness - Publications

Affiliations: 
Keele University, Keele, England, United Kingdom 
Area:
auditory neuroscience
Website:
http://www.keele.ac.uk/depts/co/auditory/CNS%20intro%202003.htm

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mahendrasingam S, Furness DN. Ultrastructural localization of the likely mechanoelectrical transduction channel protein, transmembrane-like channel 1 (TMC1) during development of cochlear hair cells. Scientific Reports. 9: 1274. PMID 30718571 DOI: 10.1038/s41598-018-37563-x  0.72
2017 Mahendrasingam S, Fettiplace R, Alagramam KN, Cross E, Furness DN. Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15. Plos One. 12: e0185285. PMID 29069081 DOI: 10.1371/journal.pone.0185285  0.72
2015 Li H, Kachelmeier A, Furness DN, Steyger PS. Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells. Frontiers in Cellular Neuroscience. 9: 130. PMID 25926770 DOI: 10.3389/fncel.2015.00130  0.8
2015 Furness DN. Molecular basis of hair cell loss. Cell and Tissue Research. 361: 387-99. PMID 25676005 DOI: 10.1007/s00441-015-2113-z  0.8
2014 Khalil M, Furness DN, Zholobenko V, Hoole D. Effect of tapeworm parasitisation on cadmium toxicity in the bioindicator copepod, Cyclops strenuus Ecological Indicators. 37: 21-26. DOI: 10.1016/j.ecolind.2013.09.033  0.8
2013 Kim KX, Beurg M, Hackney CM, Furness DN, Mahendrasingam S, Fettiplace R. The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels. The Journal of General Physiology. 142: 493-505. PMID 24127526 DOI: 10.1085/jgp.201311068  0.8
2013 Furness DN, Johnson SL, Manor U, Rüttiger L, Tocchetti A, Offenhauser N, Olt J, Goodyear RJ, Vijayakumar S, Dai Y, Hackney CM, Franz C, Di Fiore PP, Masetto S, Jones SM, et al. Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. Proceedings of the National Academy of Sciences of the United States of America. 110: 13898-903. PMID 23918390 DOI: 10.1073/pnas.1304644110  0.8
2013 Johnson SL, Kuhn S, Franz C, Ingham N, Furness DN, Knipper M, Steel KP, Adelman JP, Holley MC, Marcotti W. Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 8720-5. PMID 23650376 DOI: 10.1073/pnas.1219578110  0.8
2013 Hackney CM, Furness DN. The composition and role of cross links in mechanoelectrical transduction in vertebrate sensory hair cells. Journal of Cell Science. 126: 1721-31. PMID 23641064 DOI: 10.1242/jcs.106120  0.8
2013 Geng R, Sotomayor M, Kinder KJ, Gopal SR, Gerka-Stuyt J, Chen DH, Hardisty-Hughes RE, Ball G, Parker A, Gaudet R, Furness D, Brown SD, Corey DP, Alagramam KN. Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4395-404. PMID 23467356 DOI: 10.1523/JNEUROSCI.4514-12.2013  0.8
2013 Jenkins SI, Pickard MR, Furness DN, Yiu HH, Chari DM. Differences in magnetic particle uptake by CNS neuroglial subclasses: implications for neural tissue engineering. Nanomedicine (London, England). 8: 951-68. PMID 23173710 DOI: 10.2217/nnm.12.145  0.8
2012 Geng R, Melki S, Chen DH, Tian G, Furness DN, Oshima-Takago T, Neef J, Moser T, Askew C, Horwitz G, Holt JR, Imanishi Y, Alagramam KN. The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9485-98. PMID 22787034 DOI: 10.1523/JNEUROSCI.0311-12.2012  0.8
2012 Chen Q, Mahendrasingam S, Tickle JA, Hackney CM, Furness DN, Fettiplace R. The development, distribution and density of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells. The European Journal of Neuroscience. 36: 2302-10. PMID 22672315 DOI: 10.1111/j.1460-9568.2012.08159.x  0.8
2012 Holmseth S, Dehnes Y, Huang YH, Follin-Arbelet VV, Grutle NJ, Mylonakou MN, Plachez C, Zhou Y, Furness DN, Bergles DE, Lehre KP, Danbolt NC. The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6000-13. PMID 22539860 DOI: 10.1523/JNEUROSCI.5347-11.2012  0.8
2012 Hackney CM, Furness DN. Hair bundle structure and mechanotransduction Oxford Handbook of Auditory Science the Ear. DOI: 10.1093/oxfordhb/9780199233397.013.0008  0.8
2011 Mahendrasingam S, Bebb C, Shepard E, Furness DN. Subcellular distribution and relative expression of fibrocyte markers in the CD/1 mouse cochlea assessed by semiquantitative immunogold electron microscopy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 59: 984-1000. PMID 22043022 DOI: 10.1369/0022155411421801  0.8
2011 Alagramam KN, Goodyear RJ, Geng R, Furness DN, van Aken AF, Marcotti W, Kros CJ, Richardson GP. Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells. Plos One. 6: e19183. PMID 21532990 DOI: 10.1371/journal.pone.0019183  0.8
2011 Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S, Marcotti W. Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells. Plos Biology. 9: e1001048. PMID 21526224 DOI: 10.1371/journal.pbio.1001048  0.8
2011 Osen KK, Furness DN, Hackney CM. The border between the central and the peripheral nervous system in the cat cochlear nerve: a light and scanning electron microscopical study. Hearing Research. 277: 44-53. PMID 21447373 DOI: 10.1016/j.heares.2011.03.012  0.8
2011 Mahendrasingam S, Macdonald JA, Furness DN. Relative time course of degeneration of different cochlear structures in the CD/1 mouse model of accelerated aging. Journal of the Association For Research in Otolaryngology : Jaro. 12: 437-53. PMID 21399990 DOI: 10.1007/s10162-011-0263-6  0.8
2011 Kuhn S, Johnson SL, Furness DN, Chen J, Ingham N, Hilton JM, Steffes G, Lewis MA, Zampini V, Hackney CM, Masetto S, Holley MC, Steel KP, Marcotti W. miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 2355-60. PMID 21245307 DOI: 10.1073/pnas.1016646108  0.8
2011 Pickard MR, Jenkins SI, Koller CJ, Furness DN, Chari DM. Magnetic nanoparticle labeling of astrocytes derived for neural transplantation. Tissue Engineering. Part C, Methods. 17: 89-99. PMID 20666601 DOI: 10.1089/ten.TEC.2010.0170  0.8
2010 Jasinska M, Siucinska E, Cybulska-Klosowicz A, Pyza E, Furness DN, Kossut M, Glazewski S. Rapid, learning-induced inhibitory synaptogenesis in murine barrel field. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1176-84. PMID 20089926 DOI: 10.1523/JNEUROSCI.2970-09.2010  0.8
2010 Furness DN, Hackney CM, Evans MG. Localisation of the mechanotransducer channels in mammalian cochlear hair cells provides clues to their gating. The Journal of Physiology. 588: 765-72. PMID 20026619 DOI: 10.1113/jphysiol.2009.179614  0.8
2010 Johnson SL, Franz C, Kuhn S, Furness DN, Rüttiger L, Münkner S, Rivolta MN, Seward EP, Herschman HR, Engel J, Knipper M, Marcotti W. Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. Nature Neuroscience. 13: 45-52. PMID 20010821 DOI: 10.1038/nn.2456  0.8
2010 Furness DN, Hackney CM. Molecular Anatomy of Receptor Cells and Organ of Corti The Senses: a Comprehensive Reference. 3: 107-137. DOI: 10.1016/B978-012370880-9.00012-8  0.8
2009 Furness DN, Lawton DM, Mahendrasingam S, Hodierne L, Jagger DJ. Quantitative analysis of the expression of the glutamate-aspartate transporter and identification of functional glutamate uptake reveal a role for cochlear fibrocytes in glutamate homeostasis. Neuroscience. 162: 1307-21. PMID 19464351 DOI: 10.1016/j.neuroscience.2009.05.036  0.8
2009 Khalil M, Furness D, Polwart A, Hoole D. X-ray microanalysis (EDXMA) of cadmium-exposed eggs of Bothriocephalus acheilognathi (Cestoda: Bothriocephalidea) and the influence of this heavy metal on coracidial hatching and activity International Journal For Parasitology. 39: 1093-1098. PMID 19341741 DOI: 10.1016/j.ijpara.2009.02.023  0.8
2008 Furness DN, Dehnes Y, Akhtar AQ, Rossi DJ, Hamann M, Grutle NJ, Gundersen V, Holmseth S, Lehre KP, Ullensvang K, Wojewodzic M, Zhou Y, Attwell D, Danbolt NC. A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience. 157: 80-94. PMID 18805467 DOI: 10.1016/j.neuroscience.2008.08.043  0.8
2008 Furness DN, Mahendrasingam S, Ohashi M, Fettiplace R, Hackney CM. The dimensions and composition of stereociliary rootlets in mammalian cochlear hair cells: comparison between high- and low-frequency cells and evidence for a connection to the lateral membrane. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6342-53. PMID 18562604 DOI: 10.1523/JNEUROSCI.1154-08.2008  0.8
2008 Furness DN, Katori Y, Nirmal Kumar B, Hackney CM. The dimensions and structural attachments of tip links in mammalian cochlear hair cells and the effects of exposure to different levels of extracellular calcium. Neuroscience. 154: 10-21. PMID 18384968 DOI: 10.1016/j.neuroscience.2008.02.010  0.8
2005 Holmseth S, Dehnes Y, Bjørnsen LP, Boulland JL, Furness DN, Bergles D, Danbolt NC. Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3). Neuroscience. 136: 649-60. PMID 16344142 DOI: 10.1016/j.neuroscience.2005.07.022  0.8
2005 Schnee ME, Lawton DM, Furness DN, Benke TA, Ricci AJ. Auditory hair cell-afferent fiber synapses are specialized to operate at their best frequencies. Neuron. 47: 243-54. PMID 16039566 DOI: 10.1016/j.neuron.2005.06.004  0.8
2005 Furness DN, Katori Y, Mahendrasingam S, Hackney CM. Differential distribution of beta- and gamma-actin in guinea-pig cochlear sensory and supporting cells. Hearing Research. 207: 22-34. PMID 16024192 DOI: 10.1016/j.heares.2005.05.006  0.8
2003 Furness DN, Lawton DM. Comparative distribution of glutamate transporters and receptors in relation to afferent innervation density in the mammalian cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11296-304. PMID 14672993  0.8
2002 Furness DN, Hulme JA, Lawton DM, Hackney CM. Distribution of the glutamate/aspartate transporter GLAST in relation to the afferent synapses of outer hair cells in the guinea pig cochlea. Journal of the Association For Research in Otolaryngology : Jaro. 3: 234-47. PMID 12382100 DOI: 10.1007/s101620010064  0.8
2002 Furness DN, Karkanevatos A, West B, Hackney CM. An immunogold investigation of the distribution of calmodulin in the apex of cochlear hair cells. Hearing Research. 173: 10-20. PMID 12372631 DOI: 10.1016/S0378-5955(02)00584-1  0.8
2002 Schulte CC, Meyer J, Furness DN, Hackney CM, Kleyman TR, Gummer AW. Functional effects of a monoclonal antibody on mechanoelectrical transduction in outer hair cells. Hearing Research. 164: 190-205. PMID 11950538 DOI: 10.1016/S0378-5955(01)00431-2  0.8
2000 Walsh RM, Hackney CM, Furness DN. Regeneration of the mammalian vestibular sensory epithelium following gentamicin-induced damage. The Journal of Otolaryngology. 29: 351-60. PMID 11770143  0.8
2000 Papakostas K, Hackney CM, Furness DN. The distribution of the calcium buffer calbindin in the cochlea of the guinea-pig Clinical Otolaryngology and Allied Sciences. 25: 570-6. PMID 11123177  0.8
2000 Lawton DM, Furness DN, Lindemann B, Hackney CM. Localization of the glutamate-aspartate transporter, GLAST, in rat taste buds. The European Journal of Neuroscience. 12: 3163-71. PMID 10998100 DOI: 10.1046/j.1460-9568.2000.00207.x  0.8
1999 Löwenheim H, Furness DN, Kil J, Zinn C, Gültig K, Fero ML, Frost D, Gummer AW, Roberts JM, Rubel EW, Hackney CM, Zenner HP. Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti. Proceedings of the National Academy of Sciences of the United States of America. 96: 4084-8. PMID 10097167 DOI: 10.1073/pnas.96.7.4084  0.8
1998 Mahendrasingam S, Furness DN, Hackney CM. Ultrastructural localisation of spectrin in sensory and supporting cells of guinea-pig organ of Corti. Hearing Research. 126: 151-60. PMID 9872143 DOI: 10.1016/S0378-5955(98)00164-6  0.8
1998 Meyer J, Furness DN, Zenner HP, Hackney CM, Gummer AW. Evidence for opening of hair-cell transducer channels after tip-link loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6748-56. PMID 9712646  0.8
1998 Quint E, Furness DN, Hackney CM. The effect of explantation and neomycin on hair cells and supporting cells in organotypic cultures of the adult guinea-pig utricle. Hearing Research. 118: 157-67. PMID 9606071 DOI: 10.1016/S0378-5955(98)00026-4  0.8
1998 Walsh RM, Hackney CM, Furness DN. British Society of Audiology Short Papers Meeting on Experimental Studies of Hearing and Deafness. University of Nottingham, 22-23 September 1997: Hair-bundle degeneration and possible regeneration in the guinea-pig utricle following gentamicin-induced damage British Journal of Audiology. 32: 71.  0.8
1998 Kumar BN, Furness DN, Hackney CM. Morphological effects of low extracellular calcium on stereociliary bundles in the guinea-pig cochlea British Journal of Audiology. 32: 77-78.  0.8
1997 Furness DN, Lehre KP. Immunocytochemical localization of a high-affinity glutamate-aspartate transporter, GLAST, in the rat and guinea-pig cochlea. The European Journal of Neuroscience. 9: 1961-9. PMID 9383219 DOI: 10.1111/j.1460-9568.1997.tb00763.x  0.8
1997 Mahendrasingam S, Katori Y, Furness DN, Hackney CM. Ultrastructural localization of cadherin in the adult guinea-pig organ of Corti. Hearing Research. 111: 85-92. PMID 9307314 DOI: 10.1016/S0378-5955(97)00091-9  0.8
1997 Furness DN, Zetes DE, Hackney CM, Steele CR. Kinematic analysis of shear displacement as a means for operating mechanotransduction channels in the contact region between adjacent stereocilia of mammalian cochlear hair cells. Proceedings. Biological Sciences / the Royal Society. 264: 45-51. PMID 9061959 DOI: 10.1098/rspb.1997.0007  0.8
1997 Furness DN, Lehre KP. Immunocytochemical localization of the high affinity glutamate/aspartate transporter, GLAST, in the rat and guinea-pig cochlea British Journal of Audiology. 31: 120-121.  0.8
1997 Katori Y, Mahendrasingam S, Furness DN, Hackney CM. Localization of beta-cytoplasmic actin in guinea pig organ of Corti using post-embedding immunogold labelling British Journal of Audiology. 31: 74-75.  0.8
1997 Mahendrasingam S, Katori Y, Furness DN, Hackney CM. Localization of cadherin in guinea-pig organ of Corti using post-embedding immunogold labelling British Journal of Audiology. 31: 73-74.  0.8
1996 Furness DN, Hackney CM, Benos DJ. The binding site on cochlear stereocilia for antisera raised against renal Na+ channels is blocked by amiloride and dihydrostreptomycin. Hearing Research. 93: 136-46. PMID 8735075 DOI: 10.1016/0378-5955(95)00224-3  0.8
1996 Quint E, Hackney CM, Furness DN. The effect of neomycin on organotypic cultures of the adult guinea-pig utricle. Annals of the New York Academy of Sciences. 781: 683-5. PMID 8694476  0.8
1996 Katori Y, Hackney CM, Furness DN. Immunoreactivity of sensory hair bundles of the guinea-pig cochlea to antibodies against elastin and keratan sulphate. Cell and Tissue Research. 284: 473-9. PMID 8646765 DOI: 10.1007/s004410050608  0.8
1996 Katori Y, Furness DN, Hackney CM. The relationship between extracellular linkages and the stereociliary cytoskeleton in demembranated cochlear hair cells British Journal of Audiology. 30: 92-93.  0.8
1996 Quint E, Hackney CM, Furness DN. Effect of neomycin on the utricular epithelium of the adult guinea pig in vitro British Journal of Audiology. 30: 93-94.  0.8
1995 Hackney CM, Furness DN. Mechanotransduction in vertebrate hair cells: structure and function of the stereociliary bundle. The American Journal of Physiology. 268: C1-13. PMID 7840137  0.8
1995 Hilger AW, Furness DN, Wilson JP. The possible relationship between transient evoked otoacoustic emissions and organ of Corti irregularities in the guinea pig. Hearing Research. 84: 1-11. PMID 7642443 DOI: 10.1016/0378-5955(95)00007-Q  0.8
1993 Jiang D, Furness DN, Hackney CM, Lopez DE. Microslicing of the resin-embedded cochlea in comparison with the surface preparation technique for analysis of hair cell number and morphology. British Journal of Audiology. 27: 195-203. PMID 8241968  0.8
1993 Hackney CM, Fettiplace R, Furness DN. The functional morphology of stereociliary bundles on turtle cochlear hair cells. Hearing Research. 69: 163-75. PMID 8226337 DOI: 10.1016/0378-5955(93)90104-9  0.8
1993 Nagasawa A, Harrison RV, Mount RJ, Harada Y. Three-dimensional cytoskeletal structures of the chinchilla organ of Corti: scanning electron microscopy application of the polyethylene glycol method. Scanning Microscopy. 7: 897-906. PMID 8146617  0.8
1993 Furness DN, Hackney CM. The functional morphology of stereociliary bundles on cochlear hair cells of the turtle Journal of Physiology. 467: 352P.  0.8
1992 Hackney CM, Furness DN, Benos DJ, Woodley JF, Barratt J. Putative immunolocalization of the mechanoelectrical transduction channels in mammalian cochlear hair cells. Proceedings. Biological Sciences / the Royal Society. 248: 215-21. PMID 1354359 DOI: 10.1098/rspb.1992.0064  0.8
1992 Hackney CM, Furness DN, Benos DJ. Binding of a polyclonal antibody raised against an amiloride-sensitive Na+ channel to guinea-pig cochlear hair cells in vitro is reduced by drugs known to affect mechanoelectrical transduction Journal of Physiology. 446: 113P.  0.8
1991 Hackney CM, Furness DN, Benos DJ. Localisation of putative mechanoelectrical transducer channels in cochlear hair cells by immunoelectron microscopy. Scanning Microscopy. 5: 741-5; discussion 74. PMID 1808712  0.8
1990 Furness DN, Hackney CM. Comparative ultrastructure of subsurface cisternae in inner and outer hair cells of the guinea pig cochlea. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With the German Society For Oto-Rhino-Laryngology - Head and Neck Surgery. 247: 12-5. PMID 2310542 DOI: 10.1007/BF00240941  0.8
1990 Furness DN, Hackney CM, Hynd AN. Rotated stereociliary bundles and their relationship with the tectorial membrane in the guinea pig cochlea. Acta Oto-Laryngologica. 109: 66-75. PMID 2309561 DOI: 10.3109/00016489009107416  0.8
1990 Furness DN, Hackney CM, Steyger PS. Organization of microtubules in cochlear hair cells. Journal of Electron Microscopy Technique. 15: 261-79. PMID 2197374 DOI: 10.1002/jemt.1060150306  0.8
1989 Furness DN, Richardson GP, Russell IJ. Stereociliary bundle morphology in organotypic cultures of the mouse cochlea. Hearing Research. 38: 95-109. PMID 2708161 DOI: 10.1016/0378-5955(89)90131-7  0.8
1989 Steyger PS, Furness DN, Hackney CM, Richardson GP. Tubulin and microtubules in cochlear hair cells: comparative immunocytochemistry and ultrastructure. Hearing Research. 42: 1-16. PMID 2584155 DOI: 10.1016/0378-5955(89)90113-5  0.8
1988 Hackney CM, Furness DN. Are the stereociliary tip linkages on outer hair cells in the guinea pig cochlea sensitive to chronic application of kanamycin? Hearing Research. 35: 279-83. PMID 3198517 DOI: 10.1016/0378-5955(88)90126-8  0.8
1988 Hackney CM, Furness DN, Sayers DL. Stereociliary cross-links between adjacent inner hair cells. Hearing Research. 34: 207-11. PMID 3170364 DOI: 10.1016/0378-5955(88)90109-8  0.8
1986 Furness DN, Hackney CM. Morphological changes to the stereociliary bundles in the guinea pig cochlea after kanamycin treatment. British Journal of Audiology. 20: 253-9. PMID 3790770 DOI: 10.3109/03005368609079024  0.8
1986 Hackney CM, Furness DN. Intercellular cross-linkages between the stereociliary bundles of adjacent hair cells in the guinea pig cochlea. Cell and Tissue Research. 245: 685-8. PMID 3757021 DOI: 10.1007/BF00218573  0.8
1986 Furness DN, Hackney CM. High-resolution scanning-electron microscopy of stereocilia using the osmium-thiocarbohydrazide coating technique. Hearing Research. 21: 243-9. PMID 3522517 DOI: 10.1016/0378-5955(86)90222-4  0.8
1986 Furness DN, Hackney CM, Evans EF. The ultrastructure of stereociliary cross-links Hearing Research. 22: 79. DOI: 10.1016/0378-5955(86)90078-X  0.8
1985 Furness DN, Hackney CM. Cross-links between stereocilia in the guinea pig cochlea. Hearing Research. 18: 177-88. PMID 4044419 DOI: 10.1016/0378-5955(85)90010-3  0.8
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