Rory Curtis - Publications

Affiliations: 
Elixir Pharmaceuticals, Cambridge, MA, United States 
Area:
GAP43, glia, ion channels, regeneration, neurotrophins, GAP-43

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, et al. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity (Journal of Pharmacology and Experimental Therapeutics (2011) 339, (115-124)) Journal of Pharmacology and Experimental Therapeutics. 340: 810.  0.506
2011 Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, et al. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24. PMID 21775475 DOI: 10.1124/Jpet.111.183764  0.552
2007 DiStefano PS, Curtis R, Geddes BJ. Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan. Current Alzheimer Research. 4: 153-7. PMID 17430240 DOI: 10.2174/156720507780362038  0.557
2006 Curtis R, O'Connor G, DiStefano PS. Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell. 5: 119-26. PMID 16626391 DOI: 10.1111/J.1474-9726.2006.00205.X  0.573
2006 Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology. 26: 28-38. PMID 16354677 DOI: 10.1128/Mcb.26.1.28-38.2006  0.581
2005 Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, ... ... Curtis R, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. Journal of Medicinal Chemistry. 48: 8045-54. PMID 16335928 DOI: 10.1021/Jm050522V  0.555
2005 McDonagh T, Hixon J, DiStefano PS, Curtis R, Napper AD. Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (San Diego, Calif.). 36: 346-50. PMID 16085423 DOI: 10.1016/J.Ymeth.2005.03.005  0.551
2005 Curtis R, Geesaman BJ, DiStefano PS. Ageing and metabolism: drug discovery opportunities. Nature Reviews. Drug Discovery. 4: 569-80. PMID 15976816 DOI: 10.1038/Nrd1777  0.548
2005 Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK. Substrate-specific activation of sirtuins by resveratrol. The Journal of Biological Chemistry. 280: 17038-45. PMID 15684413 DOI: 10.1074/Jbc.M500655200  0.565
2004 Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes & Development. 18: 3004-9. PMID 15574588 DOI: 10.1101/Gad.1255404  0.565
2004 Maier SK, Westenbroek RE, McCormick KA, Curtis R, Scheuer T, Catterall WA. Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart. Circulation. 109: 1421-7. PMID 15007009 DOI: 10.1161/01.Cir.0000121421.61896.24  0.485
2003 Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T, Curtis R. Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7577-85. PMID 12930796  0.739
2002 Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature. 418: 181-6. PMID 12077604 DOI: 10.1038/Nature00882  0.742
2002 Baxter DF, Kirk M, Garcia AF, Raimondi A, Holmqvist MH, Flint KK, Bojanic D, Distefano PS, Curtis R, Xie Y. A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels. Journal of Biomolecular Screening. 7: 79-85. PMID 11897058 DOI: 10.1177/108705710200700110  0.744
2001 Qu Y, Curtis R, Lawson D, Gilbride K, Ge P, DiStefano PS, Silos-Santiago I, Catterall WA, Scheuer T. Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits. Molecular and Cellular Neurosciences. 18: 570-80. PMID 11922146 DOI: 10.1006/Mcne.2001.1039  0.763
2001 Ratcliffe CF, Westenbroek RE, Curtis R, Catterall WA. Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain. The Journal of Cell Biology. 154: 427-34. PMID 11470829 DOI: 10.1083/Jcb.200102086  0.515
2000 Holmes FE, Mahoney S, King VR, Bacon A, Kerr NC, Pachnis V, Curtis R, Priestley JV, Wynick D. Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proceedings of the National Academy of Sciences of the United States of America. 97: 11563-8. PMID 11016970 DOI: 10.1073/Pnas.210221897  0.653
2000 Alderson RF, Curtis R, Alterman AL, Lindsay RM, DiStefano PS. Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro. Brain Research. 871: 210-22. PMID 10899288 DOI: 10.1016/S0006-8993(00)02428-8  0.691
2000 Weiger TM, Holmqvist MH, Levitan IB, Clark FT, Sprague S, Huang WJ, Ge P, Wang C, Lawson D, Jurman ME, Glucksmann MA, Silos-Santiago I, DiStefano PS, Curtis R. A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3563-70. PMID 10804197 DOI: 10.1523/Jneurosci.20-10-03563.2000  0.738
1999 Davies M, Paterson IC, Stone A, Huntley S, Patel V, Curtis R, Matthews JB, Pring M, Eveson JW, Prime SS. Loss of differentiation of 4NQO-induced rat malignant oral keratinocytes correlates with metastatic dissemination and is associated with a reduced cellular response to TGF-beta1 and an altered receptor profile. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 28: 397-405. PMID 10535362 DOI: 10.1111/J.1600-0714.1999.Tb02110.X  0.347
1998 Curtis R, Tonra JR, Stark JL, Adryan KM, Park JS, Cliffer KD, Lindsay RM, DiStefano PS. Neuronal injury increases retrograde axonal transport of the neurotrophins to spinal sensory neurons and motor neurons via multiple receptor mechanisms. Molecular and Cellular Neurosciences. 12: 105-18. PMID 9790733 DOI: 10.1006/Mcne.1998.0704  0.788
1998 Tonra JR, Curtis R, Wong V, Cliffer KD, Park JS, Timmes A, Nguyen T, Lindsay RM, Acheson A, DiStefano PS. Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4374-83. PMID 9592114 DOI: 10.1523/Jneurosci.18-11-04374.1998  0.783
1998 Hackett SF, Friedman Z, Freund J, Schoenfeld C, Curtis R, DiStefano PS, Campochiaro PA. A splice variant of trkB and brain-derived neurotrophic factor are co-expressed in retinal pigmented epithelial cells and promote differentiated characteristics. Brain Research. 789: 201-12. PMID 9573364 DOI: 10.1016/S0006-8993(97)01440-6  0.626
1998 Helke CJ, Adryan KM, Fedorowicz J, Zhuo H, Park JS, Curtis R, Radley HE, Distefano PS. Axonal transport of neurotrophins by visceral afferent and efferent neurons of the vagus nerve of the rat. The Journal of Comparative Neurology. 393: 102-17. PMID 9520105 DOI: 10.1002/(Sici)1096-9861(19980330)393:1<102::Aid-Cne10>3.0.Co;2-Z  0.65
1997 Helgren ME, Cliffer KD, Torrento K, Cavnor C, Curtis R, DiStefano PS, Wiegand SJ, Lindsay RM. Neurotrophin-3 administration attenuates deficits of pyridoxine-induced large-fiber sensory neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 372-82. PMID 8987762 DOI: 10.1523/Jneurosci.17-01-00372.1997  0.672
1996 Zhuo H, Adryan' KM, Curtis R, DiStefano PS, Heike CJ. Neurotrophin (NT) receptor TrkC mRNA and retrograde transport of NT-3 in vagal motor neurons of the dorsal motor nucleus of the vagus and nucleus ambiguus Faseb Journal. 10: A130.  0.559
1995 Ilag LL, Curtis R, Glass D, Funakoshi H, Tobkes NJ, Ryan TE, Acheson A, Lindsay RM, Persson H, Yancopoulos GD. Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 607-11. PMID 7831338 DOI: 10.1073/pnas.92.2.607  0.545
1995 Stewart HJ, Curtis R, Jessen KR, Mirsky R. TGF-beta s and cAMP regulate GAP-43 expression in Schwann cells and reveal the association of this protein with the trans-Golgi network. The European Journal of Neuroscience. 7: 1761-72. PMID 7582129 DOI: 10.1111/J.1460-9568.1995.Tb00696.X  0.732
1995 Curtis R, Adryan KM, Stark JL, Park JS, Compton DL, Weskamp G, Huber LJ, Chao MV, Jaenisch R, Lee KF. Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron. 14: 1201-11. PMID 7541633 DOI: 10.1016/0896-6273(95)90267-8  0.379
1994 Curtis R, DiStefano PS. Neurotropic factors, retrograde axonal transport and cell signalling. Trends in Cell Biology. 4: 383-6. PMID 14731813 DOI: 10.1016/0962-8924(94)90045-0  0.614
1994 DiStefano PS, Curtis R. Receptor mediated retrograde axonal transport of neurotrophic factors is increased after peripheral nerve injury. Progress in Brain Research. 103: 35-42. PMID 7533913 DOI: 10.1016/S0079-6123(08)61124-3  0.649
1994 Curtis R, Scherer SS, Somogyi R, Adryan KM, Ip NY, Zhu Y, Lindsay RM, DiStefano PS. Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron. 12: 191-204. PMID 7507340 DOI: 10.1016/0896-6273(94)90163-5  0.76
1994 Curtis R, DiStefano PS. Neurotrophic factors, retrograde axonal transport and cell signalling Trends in Cell Biology. 4: 384-386. DOI: 10.1016/0962-8924(94)90045-0  0.576
1993 Curtis R. Growth-associated protein-43 (GAP-43) is expressed by glial cells of the central and peripheral nervous system Annals of the New York Academy of Sciences. 679: 407-411. PMID 8512205 DOI: 10.1111/J.1749-6632.1993.Tb18330.X  0.371
1993 Curtis R, Green D, Lindsay RM, Wilkin GP. Up-regulation of GAP-43 and growth of axons in rat spinal cord after compression injury. Journal of Neurocytology. 22: 51-64. PMID 8426193 DOI: 10.1007/Bf01183975  0.705
1993 Curtis R, Averill S, Priestley JV, Wilkin GP. The distribution of GAP-43 in normal rat spinal cord. Journal of Neurocytology. 22: 39-50. PMID 8426192 DOI: 10.1007/Bf01183974  0.644
1993 Curtis R, Adryan KM, Zhu Y, Harkness PJ, Lindsay RM, DiStefano PS. Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature. 365: 253-5. PMID 8371780 DOI: 10.1038/365253A0  0.724
1993 Davis S, Aldrich TH, Ip NY, Stahl N, Scherer S, Farruggella T, DiStefano PS, Curtis R, Panayotatos N, Gascan H. Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses. Science (New York, N.Y.). 259: 1736-9. PMID 7681218 DOI: 10.1126/Science.7681218  0.664
1992 Stewart HJ, Cowen T, Curtis R, Wilkin GP, Mirsky R, Jessen KR. GAP-43 immunoreactivity is widespread in the autonomic neurons and sensory neurons of the rat. Neuroscience. 47: 673-84. PMID 1533902 DOI: 10.1016/0306-4522(92)90175-2  0.781
1992 Curtis R, Stewart HJ, Hall SM, Wilkin GP, Mirsky R, Jessen KR. GAP-43 is expressed by nonmyelin-forming Schwann cells of the peripheral nervous system. The Journal of Cell Biology. 116: 1455-64. PMID 1531832 DOI: 10.1083/Jcb.116.6.1455  0.793
1992 Hall SM, Kent AP, Curtis R, Robertson D. Electron microscopic immunocytochemistry of GAP-43 within proximal and chronically denervated distal stumps of transected peripheral nerve. Journal of Neurocytology. 21: 820-31. PMID 1431999 DOI: 10.1007/Bf01237907  0.55
1992 Stewart HJ, Jessen KR, Curtis R, Mirsky R. Schwann cells, neurons and GAP-43. Perspectives On Developmental Neurobiology. 1: 45-52. PMID 1345685  0.707
1992 Averill S, Curtis R, wilkin GP, Priestley JV. Ultrastructural localization of GAP-43 immunoreactive terminals in the adult rat spinal cord Journal of Physiology. 446: 600P.  0.549
1991 Curtis R, Hardy R, Reynolds R, Spruce BA, Wilkin GP. Down-regulation of GAP-43 During Oligodendrocyte Development and Lack of Expression by Astrocytes In Vivo: Implications for Macroglial Differentiation. The European Journal of Neuroscience. 3: 876-86. PMID 12106454 DOI: 10.1111/J.1460-9568.1991.Tb00099.X  0.772
1990 Spruce BA, Curtis R, Wilkin GP, Glover DM. A neuropeptide precursor in cerebellum: proenkephalin exists in subpopulations of both neurons and astrocytes. The Embo Journal. 9: 1787-95. PMID 2189722  0.781
1990 Wilkin GP, Curtis R. Cell adhesion molecules and ion pumps--do ion fluxes regulate neuronal migration? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 12: 287-8. PMID 1696815 DOI: 10.1002/Bies.950120607  0.598
1990 Spruce B, Curtis R, Wilkin G, Glover D. A neuropeptide precursor in cerebellum: proenkephalin exists in subpopulations of both neurons and astrocytes. The Embo Journal. 9: 1787-1795. DOI: 10.1002/J.1460-2075.1990.Tb08303.X  0.788
1988 Curtis R, Cohen J, Fok-Seang J, Hanley MR, Gregson NA, Reynolds R, Wilkin GP. Development of macroglial cells in rat cerebellum. I. Use of antibodies to follow early in vivo development and migration of oligodendrocytes. Journal of Neurocytology. 17: 43-54. PMID 3047324 DOI: 10.1007/Bf01735376  0.745
Show low-probability matches.