Peter S. DiStefano - Publications

Affiliations: 
Elixir Pharmaceuticals, Cambridge, MA, United States 
Area:
Neurotrophins,

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J. Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987039 DOI: 10.1073/pnas.1806660115  0.72
2012 Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, et al. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity (Journal of Pharmacology and Experimental Therapeutics (2011) 339, (115-124)) Journal of Pharmacology and Experimental Therapeutics. 340: 810.  0.8
2011 Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, et al. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24. PMID 21775475 DOI: 10.1124/jpet.111.183764  0.8
2011 Qi Y, Longo KA, Giuliana DJ, Gagne S, McDonagh T, Govek E, Nolan A, Zou C, Morgan K, Hixon J, Saunders JO, Distefano PS, Geddes BJ. Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps. Bmc Physiology. 11: 1. PMID 21211044 DOI: 10.1186/1472-6793-11-1  0.8
2010 Huber JL, McBurney MW, Distefano PS, McDonagh T. SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183. Future Medicinal Chemistry. 2: 1751-9. PMID 21428798 DOI: 10.4155/fmc.10.257  0.8
2010 Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Distefano PS, Geddes BJ. The 24-hour respiratory quotient predicts energy intake and changes in body mass. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R747-54. PMID 20018821 DOI: 10.1152/ajpregu.00476.2009  0.8
2010 Longo KA, Berryman DE, Kelder B, Charoenthongtrakul S, Distefano PS, Geddes BJ, Kopchick JJ. Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 20: 73-9. PMID 19747867 DOI: 10.1016/j.ghir.2009.08.002  0.8
2009 Charoenthongtrakul S, Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, DiStefano PS, et al. Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. The Journal of Pharmacology and Experimental Therapeutics. 329: 1178-86. PMID 19252061 DOI: 10.1124/jpet.108.150193  0.8
2008 Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Qi Y, DiStefano PS, Geddes BJ. Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice. Regulatory Peptides. 150: 55-61. PMID 18453014 DOI: 10.1016/j.regpep.2008.03.011  0.8
2007 DiStefano PS, Curtis R, Geddes BJ. Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan. Current Alzheimer Research. 4: 153-7. PMID 17430240 DOI: 10.2174/156720507780362038  0.8
2006 Bingham B, Shen R, Kotnis S, Lo CF, Ozenberger BA, Ghosh N, Kennedy JD, Jacobsen JS, Grenier JM, DiStefano PS, Chiang LW, Wood A. Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 1123-31. PMID 17051583 DOI: 10.1002/cyto.a.20346  0.6
2006 Curtis R, O'Connor G, DiStefano PS. Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell. 5: 119-26. PMID 16626391 DOI: 10.1111/j.1474-9726.2006.00205.x  0.8
2006 Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology. 26: 28-38. PMID 16354677 DOI: 10.1128/MCB.26.1.28-38.2006  0.6
2005 Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, ... DiStefano PS, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. Journal of Medicinal Chemistry. 48: 8045-54. PMID 16335928 DOI: 10.1021/jm050522v  0.6
2005 McDonagh T, Hixon J, DiStefano PS, Curtis R, Napper AD. Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (San Diego, Calif.). 36: 346-50. PMID 16085423 DOI: 10.1016/j.ymeth.2005.03.005  0.6
2005 Curtis R, Geesaman BJ, DiStefano PS. Ageing and metabolism: drug discovery opportunities. Nature Reviews. Drug Discovery. 4: 569-80. PMID 15976816 DOI: 10.1038/nrd1777  0.8
2005 Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK. Substrate-specific activation of sirtuins by resveratrol. The Journal of Biological Chemistry. 280: 17038-45. PMID 15684413 DOI: 10.1074/jbc.M500655200  0.6
2004 Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes & Development. 18: 3004-9. PMID 15574588 DOI: 10.1101/gad.1255404  0.8
2004 Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Mémet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nature Immunology. 5: 1166-74. PMID 15489856 DOI: 10.1038/ni1131  0.6
2003 Naureckiene S, Ma L, Sreekumar K, Purandare U, Lo CF, Huang Y, Chiang LW, Grenier JM, Ozenberger BA, Jacobsen JS, Kennedy JD, DiStefano PS, Wood A, Bingham B. Functional characterization of Narc 1, a novel proteinase related to proteinase K. Archives of Biochemistry and Biophysics. 420: 55-67. PMID 14622975 DOI: 10.1016/j.abb.2003.09.011  0.6
2003 Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T, Curtis R. Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7577-85. PMID 12930796  0.6
2003 Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jéhanno M, Viala J, Tedin K, Taha MK, Labigne A, Zähringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (New York, N.Y.). 300: 1584-7. PMID 12791997 DOI: 10.1126/science.1084677  0.6
2002 Grenier JM, Wang L, Manji GA, Huang WJ, Al-Garawi A, Kelly R, Carlson A, Merriam S, Lora JM, Briskin M, DiStefano PS, Bertin J. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. Febs Letters. 530: 73-8. PMID 12387869 DOI: 10.1016/S0014-5793(02)03416-6  0.6
2002 Wang D, You Y, Case SM, McAllister-Lucas LM, Wang L, DiStefano PS, Nuñez G, Bertin J, Lin X. A requirement for CARMA1 in TCR-induced NF-kappa B activation. Nature Immunology. 3: 830-5. PMID 12154356 DOI: 10.1038/ni824  0.6
2002 Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature. 418: 181-6. PMID 12077604 DOI: 10.1038/nature00882  0.6
2002 Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. The Journal of Biological Chemistry. 277: 29874-80. PMID 12019269 DOI: 10.1074/jbc.M203915200  0.6
2002 Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (New York, N.Y.). 296: 530-4. PMID 11964479 DOI: 10.1126/science.1068712  0.6
2002 Baxter DF, Kirk M, Garcia AF, Raimondi A, Holmqvist MH, Flint KK, Bojanic D, Distefano PS, Curtis R, Xie Y. A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels. Journal of Biomolecular Screening. 7: 79-85. PMID 11897058 DOI: 10.1089/108705702753520369  0.6
2002 Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, Alnemri ES. CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. The Journal of Biological Chemistry. 277: 13952-8. PMID 11821383 DOI: 10.1074/jbc.M107811200  0.6
2002 Holmqvist MH, Cao J, Hernandez-Pineda R, Jacobson MD, Carroll KI, Sung MA, Betty M, Ge P, Gilbride KJ, Brown ME, Jurman ME, Lawson D, Silos-Santiago I, Xie Y, Covarrubias M, ... ... Distefano PS, et al. Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 1035-40. PMID 11805342 DOI: 10.1073/pnas.022509299  0.6
2002 Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, Mak S, Lora JM, Briskin M, Jurman M, Cao J, DiStefano PS, Bertin J. PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B. The Journal of Biological Chemistry. 277: 11570-5. PMID 11786556 DOI: 10.1074/jbc.M112208200  0.6
2001 Qu Y, Curtis R, Lawson D, Gilbride K, Ge P, DiStefano PS, Silos-Santiago I, Catterall WA, Scheuer T. Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits. Molecular and Cellular Neurosciences. 18: 570-80. PMID 11922146 DOI: 10.1006/mcne.2001.1039  0.6
2001 Tonra JR, Cliffer KD, Carson SR, Lindsay RM, Bodine SC, DiStefano PS. Reduced Ia-afferent-mediated Hoffman reflex in streptozotocin-induced diabetic rats. Experimental Neurology. 172: 220-7. PMID 11681854 DOI: 10.1006/exnr.2001.7767  1
2001 Khursigara G, Bertin J, Yano H, Moffett H, DiStefano PS, Chao MV. A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5854-63. PMID 11487608  0.6
2001 Chalazonitis A, Pham TD, Rothman TP, DiStefano PS, Bothwell M, Blair-Flynn J, Tessarollo L, Gershon MD. Neurotrophin-3 is required for the survival-differentiation of subsets of developing enteric neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5620-36. PMID 11466433  0.6
2001 Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, Philpott DJ. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. Embo Reports. 2: 736-42. PMID 11463746 DOI: 10.1093/embo-reports/kve155  0.6
2001 Holmqvist MH, Cao J, Knoppers MH, Jurman ME, Distefano PS, Rhodes KJ, Xie Y, An WF. Kinetic modulation of Kv4-mediated A-current by arachidonic acid is dependent on potassium channel interacting proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4154-61. PMID 11404400  0.6
2001 Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, Bertin J. Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis. Biochemical and Biophysical Research Communications. 284: 77-82. PMID 11374873 DOI: 10.1006/bbrc.2001.4928  0.6
2001 Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES. CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B. The Journal of Biological Chemistry. 276: 11877-82. PMID 11278692 DOI: 10.1074/jbc.M010512200  0.6
2001 Wang L, Guo Y, Huang WJ, Ke X, Poyet JL, Manji GA, Merriam S, Glucksmann MA, DiStefano PS, Alnemri ES, Bertin J. Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B. The Journal of Biological Chemistry. 276: 21405-9. PMID 11259443 DOI: 10.1074/jbc.M102488200  0.6
2001 Chiang LW, Grenier JM, Ettwiller L, Jenkins LP, Ficenec D, Martin J, Jin F, DiStefano PS, Wood A. An orchestrated gene expression component of neuronal programmed cell death revealed by cDNA array analysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 2814-9. PMID 11226323 DOI: 10.1073/pnas.051630598  0.6
2000 Bertin J, DiStefano PS. The PYRIN domain: a novel motif found in apoptosis and inflammation proteins. Cell Death and Differentiation. 7: 1273-4. PMID 11270363 DOI: 10.1038/sj.cdd.4400774  0.6
2000 Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B. The Journal of Biological Chemistry. 275: 41082-6. PMID 11053425 DOI: 10.1074/jbc.C000726200  0.6
2000 Alderson RF, Curtis R, Alterman AL, Lindsay RM, DiStefano PS. Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro. Brain Research. 871: 210-22. PMID 10899288 DOI: 10.1016/S0006-8993(00)02428-8  1
2000 Weiger TM, Holmqvist MH, Levitan IB, Clark FT, Sprague S, Huang WJ, Ge P, Wang C, Lawson D, Jurman ME, Glucksmann MA, Silos-Santiago I, DiStefano PS, Curtis R. A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3563-70. PMID 10804197  0.6
1999 Bertin J, Nir WJ, Fischer CM, Tayber OV, Errada PR, Grant JR, Keilty JJ, Gosselin ML, Robison KE, Wong GH, Glucksmann MA, DiStefano PS. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB. The Journal of Biological Chemistry. 274: 12955-8. PMID 10224040 DOI: 10.1074/jbc.274.19.12955  0.6
1999 Mizisin AP, DiStefano PS, Liu X, Garrett DN, Tonra JR. Decreased accumulation of endogenous brain-derived neurotrophic factor against constricting sciatic nerve ligatures in streptozotocin-diabetic and galactose-fed rats. Neuroscience Letters. 263: 149-52. PMID 10213157 DOI: 10.1016/S0304-3940(99)00131-7  1
1998 Curtis R, Tonra JR, Stark JL, Adryan KM, Park JS, Cliffer KD, Lindsay RM, DiStefano PS. Neuronal injury increases retrograde axonal transport of the neurotrophins to spinal sensory neurons and motor neurons via multiple receptor mechanisms. Molecular and Cellular Neurosciences. 12: 105-18. PMID 9790733 DOI: 10.1006/mcne.1998.0704  1
1998 Altar CA, DiStefano PS. Neurotrophin trafficking by anterograde transport. Trends in Neurosciences. 21: 433-7. PMID 9786341 DOI: 10.1016/S0166-2236(98)01273-9  1
1998 Cliffer KD, Tonra JR, Carson SR, Radley HE, Cavnor C, Lindsay RM, Bodine SC, DiStefano PS. Consistent repeated M- and H-Wave recording in the hind limb of rats. Muscle & Nerve. 21: 1405-13. PMID 9771663 DOI: 10.1002/(SICI)1097-4598(199811)21:11<1405::AID-MUS7>3.0.CO;2-D  1
1998 Weis J, Lie DC, Ragoss U, Züchner SL, Schröder JM, Karpati G, Farruggella T, Stahl N, Yancopoulos GD, DiStefano PS. Increased expression of CNTF receptor alpha in denervated human skeletal muscle. Journal of Neuropathology and Experimental Neurology. 57: 850-7. PMID 9737548  1
1998 Mizisin AP, Kalichman MW, Bache M, Dines KC, DiStefano PS. NT-3 attenuates functional and structural disorders in sensory nerves of galactose-fed rats. Journal of Neuropathology and Experimental Neurology. 57: 803-13. PMID 9737543  1
1998 Bowen DC, Park JS, Bodine S, Stark JL, Valenzuela DM, Stitt TN, Yancopoulos GD, Lindsay RM, Glass DJ, DiStefano PS. Localization and regulation of MuSK at the neuromuscular junction. Developmental Biology. 199: 309-19. PMID 9698449 DOI: 10.1006/dbio.1998.8936  1
1998 Croll SD, Chesnutt CR, Rudge JS, Acheson A, Ryan TE, Siuciak JA, DiStefano PS, Wiegand SJ, Lindsay RM. Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain. Experimental Neurology. 152: 20-33. PMID 9682009 DOI: 10.1006/exnr.1998.6836  1
1998 Schmidt RE, Dorsey DA, Selznick LA, DiStefano PS, Carroll SL, Beaudet LN, Roth KA. Neurotrophin sensitivity of prevertebral and paravertebral rat sympathetic autonomic ganglia. Journal of Neuropathology and Experimental Neurology. 57: 158-67. PMID 9600208  0.6
1998 Tonra JR, Curtis R, Wong V, Cliffer KD, Park JS, Timmes A, Nguyen T, Lindsay RM, Acheson A, DiStefano PS. Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4374-83. PMID 9592114  1
1998 Hackett SF, Friedman Z, Freund J, Schoenfeld C, Curtis R, DiStefano PS, Campochiaro PA. A splice variant of trkB and brain-derived neurotrophic factor are co-expressed in retinal pigmented epithelial cells and promote differentiated characteristics. Brain Research. 789: 201-12. PMID 9573364 DOI: 10.1016/S0006-8993(97)01440-6  1
1998 Helke CJ, Adryan KM, Fedorowicz J, Zhuo H, Park JS, Curtis R, Radley HE, Distefano PS. Axonal transport of neurotrophins by visceral afferent and efferent neurons of the vagus nerve of the rat. The Journal of Comparative Neurology. 393: 102-17. PMID 9520105 DOI: 10.1002/(SICI)1096-9861(19980330)393:1<102::AID-CNE10>3.0.CO;2-Z  1
1998 Cliffer KD, Siuciak JA, Carson SR, Radley HE, Park JS, Lewis DR, Zlotchenko E, Nguyen T, Garcia K, Tonra JR, Stambler N, Cedarbaum JM, Bodine SC, Lindsay RM, DiStefano PS. Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat. Annals of Neurology. 43: 46-55. PMID 9450768 DOI: 10.1002/ana.410430111  1
1997 Mizisin AP, Bache M, DiStefano PS, Acheson A, Lindsay RM, Calcutt NA. BDNF attenuates functional and structural disorders in nerves of galactose-fed rats. Journal of Neuropathology and Experimental Neurology. 56: 1290-301. PMID 9413278  1
1997 Mizisin AP, Calcutt NA, DiStefano PS, Acheson A, Longo FM. Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves from galactose-fed and normal rats. Diabetes. 46: 647-52. PMID 9075806  1
1997 Johnson F, Hohmann SE, DiStefano PS, Bottjer SW. Neurotrophins suppress apoptosis induced by deafferentation of an avian motor-cortical region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2101-11. PMID 9045737  1
1997 Helgren ME, Cliffer KD, Torrento K, Cavnor C, Curtis R, DiStefano PS, Wiegand SJ, Lindsay RM. Neurotrophin-3 administration attenuates deficits of pyridoxine-induced large-fiber sensory neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 372-82. PMID 8987762  1
1996 Glass DJ, DeChiara TM, Stitt TN, DiStefano PS, Valenzuela DM, Yancopoulos GD. The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin. Cold Spring Harbor Symposia On Quantitative Biology. 61: 435-44. PMID 9246472  1
1996 DiStefano PS, Boulton TG, Stark JL, Zhu Y, Adryan KM, Ryan TE, Lindsay RM. Ciliary neurotrophic factor induces down-regulation of its receptor and desensitization of signal transduction pathways in vivo: non-equivalence with pharmacological activity. The Journal of Biological Chemistry. 271: 22839-46. PMID 8798462 DOI: 10.1074/jbc.271.37.22839  1
1996 Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD. Agrin acts via a MuSK receptor complex. Cell. 85: 513-23. PMID 8653787 DOI: 10.1016/S0092-8674(00)81252-0  1
1996 DeChiara TM, Bowen DC, Valenzuela DM, Simmons MV, Poueymirou WT, Thomas S, Kinetz E, Compton DL, Rojas E, Park JS, Smith C, DiStefano PS, Glass DJ, Burden SJ, Yancopoulos GD. The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell. 85: 501-12. PMID 8653786 DOI: 10.1016/S0092-8674(00)81251-9  1
1996 Cedarbaum JM, DeStefano PS, Lakings DB, Lindsay RM. Re: Pharmacokinetics and pharmacodynamics of rHCNTF in rodents. Annals of Neurology. 39: 552-4. PMID 8619536 DOI: 10.1002/ana.410390420  1
1996 Zhuo H, Adryan' KM, Curtis R, DiStefano PS, Heike CJ. Neurotrophin (NT) receptor TrkC mRNA and retrograde transport of NT-3 in vagal motor neurons of the dorsal motor nucleus of the vagus and nucleus ambiguus Faseb Journal. 10: A130.  1
1995 Ohara S, Tantuwaya V, DiStefano PS, Schmidt RE. Exogenous NT-3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury. Brain Research. 699: 143-8. PMID 8616605 DOI: 10.1016/0006-8993(95)01021-M  1
1995 Stitt TN, Conn G, Gore M, Lai C, Bruno J, Radziejewski C, Mattsson K, Fisher J, Gies DR, Jones PF. The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. Cell. 80: 661-70. PMID 7867073 DOI: 10.1016/0092-8674(95)90520-0  1
1995 Ilag LL, Curtis R, Glass D, Funakoshi H, Tobkes NJ, Ryan TE, Acheson A, Lindsay RM, Persson H, Yancopoulos GD. Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 607-11. PMID 7831338 DOI: 10.1073/pnas.92.2.607  1
1995 Anderson KD, Alderson RF, Altar CA, DiStefano PS, Corcoran TL, Lindsay RM, Wiegand SJ. Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors. The Journal of Comparative Neurology. 357: 296-317. PMID 7665731 DOI: 10.1002/cne.903570209  1
1995 Valenzuela DM, Stitt TN, DiStefano PS, Rojas E, Mattsson K, Compton DL, Nuñez L, Park JS, Stark JL, Gies DR. Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury. Neuron. 15: 573-84. PMID 7546737 DOI: 10.1016/0896-6273(95)90146-9  1
1995 Curtis R, Adryan KM, Stark JL, Park JS, Compton DL, Weskamp G, Huber LJ, Chao MV, Jaenisch R, Lee KF. Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron. 14: 1201-11. PMID 7541633 DOI: 10.1016/0896-6273(95)90267-8  1
1994 Curtis R, DiStefano PS. Neurotropic factors, retrograde axonal transport and cell signalling. Trends in Cell Biology. 4: 383-6. PMID 14731813  0.8
1994 Helgren ME, Squinto SP, Davis HL, Parry DJ, Boulton TG, Heck CS, Zhu Y, Yancopoulos GD, Lindsay RM, DiStefano PS. Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell. 76: 493-504. PMID 8313470 DOI: 10.1016/0092-8674(94)90113-9  1
1994 DiStefano PS, Curtis R. Receptor mediated retrograde axonal transport of neurotrophic factors is increased after peripheral nerve injury. Progress in Brain Research. 103: 35-42. PMID 7533913  1
1994 Lindsay RM, Wiegand SJ, Altar CA, DiStefano PS. Neurotrophic factors: from molecule to man. Trends in Neurosciences. 17: 182-90. PMID 7520198 DOI: 10.1016/0166-2236(94)90099-X  1
1994 Curtis R, Scherer SS, Somogyi R, Adryan KM, Ip NY, Zhu Y, Lindsay RM, DiStefano PS. Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron. 12: 191-204. PMID 7507340 DOI: 10.1016/0896-6273(94)90163-5  1
1994 Curtis R, DiStefano PS. Neurotrophic factors, retrograde axonal transport and cell signalling Trends in Cell Biology. 4: 384-386. DOI: 10.1016/0962-8924(94)90045-0  1
1993 DiStefano PS, Chelsea DM, Schick CM, McKelvy JF. Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2405-14. PMID 8501514  1
1993 Altar CA, Criden MR, Lindsay RM, DiStefano PS. Characterization and topography of high-affinity 125I-neurotrophin-3 binding to mammalian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 733-43. PMID 8426234  1
1993 Curtis R, Adryan KM, Zhu Y, Harkness PJ, Lindsay RM, DiStefano PS. Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature. 365: 253-5. PMID 8371780 DOI: 10.1038/365253a0  1
1993 DiStefano PS. Neurotrophic factors in the treatment of motor neuron disease and trauma. Experimental Neurology. 124: 56-9. PMID 8282081 DOI: 10.1006/exnr.1993.1174  1
1993 Lindner MD, Gordon DD, Miller JM, Tariot PN, McDaniel KD, Hamill RW, DiStefano PS, Loy R. Increased levels of truncated nerve growth factor receptor in urine of mildly demented patients with Alzheimer's disease. Archives of Neurology. 50: 1054-60. PMID 8215963 DOI: 10.1001/archneur.1993.00540100049013  1
1993 Morse JK, Wiegand SJ, Anderson K, You Y, Cai N, Carnahan J, Miller J, DiStefano PS, Altar CA, Lindsay RM. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4146-56. PMID 8080477  1
1993 Davis S, Aldrich TH, Ip NY, Stahl N, Scherer S, Farruggella T, DiStefano PS, Curtis R, Panayotatos N, Gascan H. Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses. Science (New York, N.Y.). 259: 1736-9. PMID 7681218  1
1993 DiStefano PS. Chapter 2. Pharmacology of Neurotrophic Factors in Models of Neurodegenerative Disease Annual Reports in Medicinal Chemistry. 28: 11-17. DOI: 10.1016/S0065-7743(08)60872-6  1
1992 Radziejewski C, Robinson RC, DiStefano PS, Taylor JW. Dimeric structure and conformational stability of brain-derived neurotrophic factor and neurotrophin-3. Biochemistry. 31: 4431-6. PMID 1581298  1
1992 DiStefano PS, Friedman B, Radziejewski C, Alexander C, Boland P, Schick CM, Lindsay RM, Wiegand SJ. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron. 8: 983-93. PMID 1375039 DOI: 10.1016/0896-6273(92)90213-W  1
1992 Matheny C, DiStefano PS, Milbrandt J. Differential activation of NGF receptor and early response genes in neural crest-derived cells. Brain Research. Molecular Brain Research. 13: 75-81. PMID 1315920 DOI: 10.1016/0169-328X(92)90046-E  1
1991 DiStefano PS, Clagett-Dame M, Chelsea DM, Loy R. Developmental regulation of human truncated nerve growth factor receptor. Annals of Neurology. 29: 13-20. PMID 1847613 DOI: 10.1002/ana.410290105  1
1991 Squinto SP, Stitt TN, Aldrich TH, Davis S, Bianco SM, Radziejewski C, Glass DJ, Masiakowski P, Furth ME, Valenzuela DM. trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell. 65: 885-93. PMID 1710174 DOI: 10.1016/0092-8674(91)90395-F  1
1990 Loy R, Heyer D, Clagett-Dame M, DiStefano PS. Localization of NGF receptors in normal and Alzheimer's basal forebrain with monoclonal antibodies against the truncated form of the receptor. Journal of Neuroscience Research. 27: 651-64. PMID 1964180 DOI: 10.1002/jnr.490270426  1
1990 DiStefano PS, Chelsea DM. Regulation of Schwann cell surface and truncated nerve growth factor receptors in vitro by axonal components. Brain Research. 534: 340-4. PMID 1963563 DOI: 10.1016/0006-8993(90)90154-4  1
1990 Clagett-Dame M, Chung C, Chao MV, DiStefano PS. Monoclonal antibodies to the cell surface and a soluble form of the human nerve growth factor receptor. Journal of Neuroscience Research. 27: 642-50. PMID 1706784 DOI: 10.1002/jnr.490270425  1
1988 DiStefano PS, Johnson EM. Identification of a truncated form of the nerve growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 270-4. PMID 2829174  1
1988 DiStefano PS, Johnson EM. Nerve growth factor receptors on cultured rat Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 231-41. PMID 2828562  1
1988 Johnson EM, Taniuchi M, DiStefano PS. Expression and possible function of nerve growth factor receptors on Schwann cells. Trends in Neurosciences. 11: 299-304. PMID 2465632 DOI: 10.1016/0166-2236(88)90090-2  1
1988 Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. The Journal of Cell Biology. 106: 829-44. PMID 2450099  0.6
1985 DiStefano PS, Brown OM. Biochemical correlates of morphine withdrawal. 2. Effects of clonidine. The Journal of Pharmacology and Experimental Therapeutics. 233: 339-44. PMID 4039756  1
1985 DiStefano PS, Schweitzer JB, Taniuchi M, Johnson EM. Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor. The Journal of Cell Biology. 101: 1107-14. PMID 2993314  1
1985 DiStefano PS, Brown OM. Biochemical correlates of morphine withdrawal. 1. Characterization in the adrenal medulla and locus ceruleus. The Journal of Pharmacology and Experimental Therapeutics. 233: 333-8. PMID 2860239  1
1984 DiStefano PS, Carroll MA, Brown OM. Clonidine blocks the biochemical changes in opiate withdrawal Federation Proceedings. 43: no. 2687.  1
1983 DiStefano PS, Brown OM. Rat adrenal catecholamines and their biosynthesizing enzymes during opiate withdrawal Federation Proceedings. 42: No. 2139.  1
1982 Wooten GF, DiStefano P, Collins RC. Regional cerebral glucose utilization during morphine withdrawal in the rat. Proceedings of the National Academy of Sciences of the United States of America. 79: 3360-4. PMID 6954484  1
1982 Distefano PS, Brown OM. Tyrosine hydroxylase and catechloamine levels in rat adrenal and LC during opiate withdrawal Federation Proceedings. 41: No. 4591.  1
1980 Distefano P, Fox G, Johnson EM. Characterization of the clonidine withdrawal syndrome in the normotensive rat Journal of Pharmacology and Experimental Therapeutics. 214: 263-268. PMID 6104723  1
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