Eugene M. Johnson - Publications

Affiliations: 
Washington University School of Medicine, St. Louis, MO, United States 

186 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bartus RT, Johnson EM. Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned? Neurobiology of Disease. PMID 27063798 DOI: 10.1016/J.Nbd.2016.03.027  0.12
2016 Bartus RT, Johnson EM. Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next? Neurobiology of Disease. PMID 27063797 DOI: 10.1016/J.Nbd.2016.03.026  0.12
2016 Daigle JG, Krishnamurthy K, Ramesh N, Casci I, Monaghan J, McAvoy K, Godfrey EW, Daniel DC, Johnson EM, Monahan Z, Shewmaker F, Pasinelli P, Pandey UB. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity. Acta Neuropathologica. PMID 26728149 DOI: 10.1007/S00401-015-1530-0  0.04
2015 Johnson EM, Roberts M, Mozaffar T, Young P, Quartel A, Berger KI. Pulmonary function tests (maximum inspiratory pressure, maximum expiratory pressure, vital capacity, forced vital capacity) predict ventilator use in late-onset Pompe disease. Neuromuscular Disorders : Nmd. PMID 26794303 DOI: 10.1016/j.nmd.2015.11.009  0.01
2015 Fraser M, Brown Z, Houldsworth M, Borman AM, Johnson EM. Rapid identification of 6328 isolates of pathogenic yeasts using MALDI-ToF MS and a simplified, rapid extraction procedure that is compatible with the Bruker Biotyper platform and database. Medical Mycology. PMID 26591008 DOI: 10.1093/mmy/myv085  0.01
2015 Schmidt KL, Johnson EM. Direct Influence: Past and Present. Journal For Nurses in Professional Development. 31: 345-6. PMID 26580467 DOI: 10.1097/NND.0000000000000215  0.01
2015 Rajendran R, Sherry L, Nile CJ, Sherriff A, Johnson E, Hanson M, Williams C, Munro C, Jones B, Ramage G. Biofilm formation is a risk factor for mortality in patients with Candida albicans bloodstream infection - Scotland, 2012-2013. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 26432192 DOI: 10.1016/j.cmi.2015.09.018  0.01
2015 Barrett AW, Noden BH, Gruntmeir JM, Holland T, Mitcham JR, Martin JE, Johnson EM, Little SE. County Scale Distribution of Amblyomma americanum (Ixodida: Ixodidae) in Oklahoma: Addressing Local Deficits in Tick Maps Based on Passive Reporting. Journal of Medical Entomology. 52: 269-73. PMID 26336311 DOI: 10.1093/jme/tju026  0.01
2015 Russo MJ, Jeevanandam V, Hur MJ, Johnson EM, Siffring T, Shah AP, Raman J. Prophylactic Subclavian Artery Intraaortic Balloon Counter-Pulsation is Safe in High-Risk Cardiac Surgery Patients. Asaio Journal (American Society For Artificial Internal Organs : 1992). 61: e36-9. PMID 26313557 DOI: 10.1097/MAT.0000000000000237  0.01
2015 Gibb SL, Zhao Y, Potter D, Hylin MJ, Bruhn R, Baimukanova G, Zhao J, Xue H, Abdel-Mohsen M, Pillai SK, Moore AN, Johnson EM, Cox CS, Dash PK, Pati S. TIMP3 attenuates the loss of neural stem cells, mature neurons and neurocognitive dysfunction in Traumatic Brain Injury. Stem Cells (Dayton, Ohio). PMID 26299440 DOI: 10.1002/Stem.2189  0.01
2015 Herd HR, Sula MM, Starkey LA, Panciera RJ, Johnson EM, Snider TA, Holbrook TC. Sarcocystis fayeri-Induced Granulomatous and Eosinophilic Myositis in 2 Related Horses. Veterinary Pathology. PMID 25957356 DOI: 10.1177/0300985815584073  0.01
2015 Bartus RT, Kordower JH, Johnson EM, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies. Neurobiology of Disease. 78: 162-71. PMID 25841760 DOI: 10.1016/J.Nbd.2015.03.023  0.12
2014 Appari A, Johnson EM, Anthony DL. Information technology and hospital patient safety: a cross-sectional study of US acute care hospitals. The American Journal of Managed Care. 20: eSP39-47. PMID 25811818  0.01
2013 Golden JP, Demaro JA, Knoten A, Hoshi M, Pehek E, Johnson EM, Gereau RW, Jain S. Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17095-107. PMID 24155314 DOI: 10.1523/Jneurosci.0890-13.2013  1
2013 Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM, Bartus RT. Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiology of Disease. 58: 38-48. PMID 23631873 DOI: 10.1016/J.Nbd.2013.04.011  1
2011 Bartus RT, Brown L, Wilson A, Kruegel B, Siffert J, Johnson EM, Kordower JH, Herzog CD. Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease. Neurobiology of Disease. 44: 38-52. PMID 21704161 DOI: 10.1016/J.Nbd.2011.05.026  1
2011 Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Siffert J, Johnson EM, Olanow CW, Mufson EJ, Kordower JH. Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 27-36. PMID 21322017 DOI: 10.1002/Mds.23442  1
2010 Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RW, Johnson EM, Jain S. RET signaling is required for survival and normal function of nonpeptidergic nociceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3983-94. PMID 20237269 DOI: 10.1523/Jneurosci.5930-09.2010  1
2009 Valdez R, Johnson EM, Belcher JA, Fuini JF, Brancaleon L. Porphyrins affect the self-assembly of tubulin in solution. Biophysical Chemistry. 145: 98-104. PMID 19819610 DOI: 10.1016/J.Bpc.2009.09.006  0.01
2008 Kalli KR, Krco CJ, Hartmann LC, Goodman K, Maurer MJ, Yu C, Johnson EM, Erskine CL, Disis ML, Wettstein PJ, Fikes JD, Beebe M, Ishioka G, Knutson KL. An HLA-DR-degenerate epitope pool detects insulin-like growth factor binding protein 2-specific immunity in patients with cancer. Cancer Research. 68: 4893-901. PMID 18559537 DOI: 10.1158/0008-5472.Can-07-6726  0.01
2008 Encinas M, Rozen EJ, Dolcet X, Jain S, Comella JX, Milbrandt J, Johnson EM. Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death and Differentiation. 15: 1510-21. PMID 18497757 DOI: 10.1038/Cdd.2008.76  1
2008 Brantley MA, Jain S, Barr EE, Johnson EM, Milbrandt J. Neurturin-mediated ret activation is required for retinal function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4123-35. PMID 18417692 DOI: 10.1523/Jneurosci.0249-08.2008  1
2007 Tian F, Johnson EM, Zamarripa M, Sansone S, Brancaleon L. Binding of porphyrins to tubulin heterodimers. Biomacromolecules. 8: 3767-78. PMID 18020394 DOI: 10.1021/Bm700687X  0.01
2007 Gustin JA, Yang M, Johnson EM, Milbrandt J. Deciphering adaptor specificity in GFL-dependent RET-mediated proliferation and neurite outgrowth. Journal of Neurochemistry. 102: 1184-94. PMID 17663753 DOI: 10.1111/J.1471-4159.2007.04624.X  1
2007 Pierchala BA, Tsui CC, Milbrandt J, Johnson EM. NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation. Journal of Neurochemistry. 100: 1169-76. PMID 17241133 DOI: 10.1111/J.1471-4159.2006.04292.X  1
2006 Jain S, Golden JP, Wozniak D, Pehek E, Johnson EM, Milbrandt J. RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11230-8. PMID 17065462 DOI: 10.1523/Jneurosci.1876-06.2006  1
2006 Besirli CG, Johnson EM. The activation loop phosphorylation of protein kinase D is an early marker of neuronal DNA damage. Journal of Neurochemistry. 99: 218-25. PMID 16911582 DOI: 10.1111/J.1471-4159.2006.04116.X  1
2006 Pierchala BA, Milbrandt J, Johnson EM. Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2777-87. PMID 16525057 DOI: 10.1523/Jneurosci.3420-05.2006  1
2006 Jain S, Encinas M, Johnson EM, Milbrandt J. Critical and distinct roles for key RET tyrosine docking sites in renal development. Genes & Development. 20: 321-33. PMID 16452504 DOI: 10.1101/Gad.1387206  1
2005 Besirli CG, Wagner EF, Johnson EM. The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. The Journal of Cell Biology. 170: 401-11. PMID 16061693 DOI: 10.1083/Jcb.200501138  1
2005 Pepose JS, Johnson EM. Is there a role for neurotrophin treatment of the ocular surface following laser in situ keratomileusis (LASIK)? American Journal of Ophthalmology. 139: 1090-4. PMID 15953442 DOI: 10.1016/J.Ajo.2005.03.064  1
2005 Wei L, Cui L, Snider BJ, Rivkin M, Yu SS, Lee CS, Adams LD, Gottlieb DI, Johnson EM, Yu SP, Choi DW. Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiology of Disease. 19: 183-93. PMID 15837573 DOI: 10.1016/J.Nbd.2004.12.016  1
2005 Leitner ML, Wang LH, Osborne PA, Golden JP, Milbrandt J, Johnson EM. Expression and function of GDNF family ligands and receptors in the carotid body. Experimental Neurology. 191: S68-79. PMID 15629763 DOI: 10.1016/J.Expneurol.2004.08.013  1
2005 Lee CS, Tee LY, Dusenbery S, Takata T, Golden JP, Pierchala BA, Gottlieb DI, Johnson EM, Choi DW, Snider BJ. Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells. Experimental Neurology. 191: 65-76. PMID 15589513 DOI: 10.1016/J.Expneurol.2004.08.025  1
2005 Wang LH, Paden AJ, Johnson EM. Mixed-lineage kinase inhibitors require the activation of Trk receptors to maintain long-term neuronal trophism and survival. The Journal of Pharmacology and Experimental Therapeutics. 312: 1007-19. PMID 15525794 DOI: 10.1124/Jpet.104.077800  1
2004 Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J. GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 44: 623-36. PMID 15541311 DOI: 10.1016/J.Neuron.2004.10.032  1
2004 Jain S, Naughton CK, Yang M, Strickland A, Vij K, Encinas M, Golden J, Gupta A, Heuckeroth R, Johnson EM, Milbrandt J. Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis. Development (Cambridge, England). 131: 5503-13. PMID 15469971 DOI: 10.1242/Dev.01421  1
2004 Crowder RJ, Enomoto H, Yang M, Johnson EM, Milbrandt J. Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth. The Journal of Biological Chemistry. 279: 42072-81. PMID 15286081 DOI: 10.1074/Jbc.M403726200  1
2004 Pierchala BA, Ahrens RC, Paden AJ, Johnson EM. Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways. The Journal of Biological Chemistry. 279: 27986-93. PMID 15117960 DOI: 10.1074/Jbc.M312237200  1
2004 Encinas M, Crowder RJ, Milbrandt J, Johnson EM. Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. The Journal of Biological Chemistry. 279: 18262-9. PMID 14766744 DOI: 10.1074/Jbc.M400505200  1
2004 Wang LH, Besirli CG, Johnson EM. Mixed-lineage kinases: a target for the prevention of neurodegeneration. Annual Review of Pharmacology and Toxicology. 44: 451-74. PMID 14744254 DOI: 10.1146/Annurev.Pharmtox.44.101802.121840  1
2004 Burke WJ, Li SW, Chung HD, Ruggiero DA, Kristal BS, Johnson EM, Lampe P, Kumar VB, Franko M, Williams EA, Zahm DS. Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases. Neurotoxicology. 25: 101-15. PMID 14697885 DOI: 10.1016/S0161-813X(03)00090-1  1
2004 Putcha GV, Johnson EM. Men are but worms: neuronal cell death in C elegans and vertebrates. Cell Death and Differentiation. 11: 38-48. PMID 14647239 DOI: 10.1038/Sj.Cdd.4401352  1
2004 Golden JP, Johnson EM. Models of chemotherapy drug-induced peripheral neuropathy Drug Discovery Today: Disease Models. 1: 186-191. DOI: 10.1016/J.Ddmod.2004.09.005  1
2003 Golden JP, Milbrandt J, Johnson EM. Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. Experimental Neurology. 184: 447-55. PMID 14637114 DOI: 10.1016/J.Expneurol.2003.07.999  1
2003 Besirli CG, Deckwerth TL, Crowder RJ, Freeman RS, Johnson EM. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death and Differentiation. 10: 1045-58. PMID 12934079 DOI: 10.1038/Sj.Cdd.4401259  1
2003 Chang LK, Schmidt RE, Johnson EM. Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death. The Journal of Cell Biology. 162: 245-56. PMID 12876275 DOI: 10.1083/Jcb.200302109  1
2003 Putcha GV, Le S, Frank S, Besirli CG, Clark K, Chu B, Alix S, Youle RJ, LaMarche A, Maroney AC, Johnson EM. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron. 38: 899-914. PMID 12818176 DOI: 10.1016/S0896-6273(03)00355-6  1
2003 Besirli CG, Johnson EM. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents. The Journal of Biological Chemistry. 278: 22357-66. PMID 12684520 DOI: 10.1074/Jbc.M300742200  1
2002 Harris C, Maroney AC, Johnson EM. Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis. Journal of Neurochemistry. 83: 992-1001. PMID 12421372 DOI: 10.1046/J.1471-4159.2002.01219.X  1
2002 Deshmukh M, Du C, Wang X, Johnson EM. Exogenous smac induces competence and permits caspase activation in sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8018-27. PMID 12223555 DOI: 10.1523/Jneurosci.22-18-08018.2002  1
2002 Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J. Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 35: 267-82. PMID 12160745 DOI: 10.1016/S0896-6273(02)00774-2  1
2002 Tsui-Pierchala BA, Encinas M, Milbrandt J, Johnson EM. Lipid rafts in neuronal signaling and function. Trends in Neurosciences. 25: 412-7. PMID 12127758 DOI: 10.1016/S0166-2236(02)02215-4  1
2002 Tsui-Pierchala BA, Ahrens RC, Crowder RJ, Milbrandt J, Johnson EM. The long and short isoforms of Ret function as independent signaling complexes. The Journal of Biological Chemistry. 277: 34618-25. PMID 12091387 DOI: 10.1074/Jbc.M203580200  1
2002 Blesch A, Lu P, Tuszynski MH. Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Research Bulletin. 57: 833-8. PMID 12031281 DOI: 10.1016/S0361-9230(01)00774-2  1
2002 Chang LK, Putcha GV, Deshmukh M, Johnson EM. Mitochondrial involvement in the point of no return in neuronal apoptosis. Biochimie. 84: 223-31. PMID 12022953 DOI: 10.1016/S0300-9084(02)01372-X  1
2002 Chang LK, Johnson EM. Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition. The Journal of Cell Biology. 157: 771-81. PMID 12021257 DOI: 10.1083/Jcb.200112130  1
2002 Rakowicz WP, Staples CS, Milbrandt J, Brunstrom JE, Johnson EM. Glial cell line-derived neurotrophic factor promotes the survival of early postnatal spinal motor neurons in the lateral and medial motor columns in slice culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3953-62. PMID 12019314 DOI: 10.1523/Jneurosci.22-10-03953.2002  1
2002 Putcha GV, Harris CA, Moulder KL, Easton RM, Thompson CB, Johnson EM. Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice. The Journal of Cell Biology. 157: 441-53. PMID 11980919 DOI: 10.1083/Jcb.200110108  1
2002 Zhou Y, Zhang W, Easton R, Ray JW, Lampe P, Jiang Z, Brunkan AL, Goate A, Johnson EM, Wu JY. Presenilin-1 protects against neuronal apoptosis caused by its interacting protein PAG. Neurobiology of Disease. 9: 126-38. PMID 11895366 DOI: 10.1006/Nbdi.2001.0472  1
2002 Tsui-Pierchala BA, Milbrandt J, Johnson EM. NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons. Neuron. 33: 261-73. PMID 11804573 DOI: 10.1016/S0896-6273(01)00585-2  1
2002 Xia S, Lampe PA, Deshmukh M, Yang A, Brown BS, Rothman SM, Johnson EM, Yu SP. Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 114-22. PMID 11756494 DOI: 10.1523/Jneurosci.22-01-00114.2002  1
2002 Harris CA, Deshmukh M, Tsui-Pierchala B, Maroney AC, Johnson EM. Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 103-13. PMID 11756493 DOI: 10.1523/Jneurosci.22-01-00103.2002  1
2001 Enomoto H, Crawford PA, Gorodinsky A, Heuckeroth RO, Johnson EM, Milbrandt J. RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development (Cambridge, England). 128: 3963-74. PMID 11641220  1
2001 Hashino E, Shero M, Junghans D, Rohrer H, Milbrandt J, Johnson EM. GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development. Development (Cambridge, England). 128: 3773-82. PMID 11585803  0.52
2001 Harris CA, Johnson EM. BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. The Journal of Biological Chemistry. 276: 37754-60. PMID 11495903 DOI: 10.1074/Jbc.M104073200  1
2001 Putcha GV, Moulder KL, Golden JP, Bouillet P, Adams JA, Strasser A, Johnson EM. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron. 29: 615-28. PMID 11301022 DOI: 10.1016/S0896-6273(01)00238-0  1
2001 Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM. c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1464-72. PMID 11222636 DOI: 10.1523/Jneurosci.21-05-01464.2001  1
2000 Enomoto H, Heuckeroth RO, Golden JP, Johnson EM, Milbrandt J. Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Development (Cambridge, England). 127: 4877-89. PMID 11044402  1
2000 Tsui-Pierchala BA, Putcha GV, Johnson EM. Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7228-37. PMID 11007879 DOI: 10.1523/Jneurosci.20-19-07228.2000  1
2000 Hongo JA, Tsai SP, Moffat B, Schroeder KA, Jung C, Chuntharapai A, Lampe PA, Johnson EM, de Sauvage FJ, Armanini M, Phillips H, Devaux B. Characterization of novel neutralizing monoclonal antibodies specific to human neurturin. Hybridoma. 19: 303-15. PMID 11001403 DOI: 10.1089/027245700429855  1
2000 Deshmukh M, Kuida K, Johnson EM. Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization. The Journal of Cell Biology. 150: 131-43. PMID 10893262 DOI: 10.1083/Jcb.150.1.131  1
2000 Putcha GV, Deshmukh M, Johnson EM. Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation. The Journal of Cell Biology. 149: 1011-8. PMID 10831605 DOI: 10.1083/Jcb.149.5.1011  1
2000 Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron. 25: 611-23. PMID 10774729 DOI: 10.1016/S0896-6273(00)81064-8  0.48
2000 Deshmukh M, Johnson EM. Staurosporine-induced neuronal death: multiple mechanisms and methodological implications. Cell Death and Differentiation. 7: 250-61. PMID 10745270 DOI: 10.1038/Sj.Cdd.4400641  1
2000 Ho TW, Bristol LA, Coccia C, Li Y, Milbrandt J, Johnson E, Jin L, Bar-Peled O, Griffin JW, Rothstein JD. TGFbeta trophic factors differentially modulate motor axon outgrowth and protection from excitotoxicity. Experimental Neurology. 161: 664-75. PMID 10686085 DOI: 10.1006/Exnr.1999.7290  1
2000 Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM. Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Experimental Neurology. 161: 203-11. PMID 10683286 DOI: 10.1006/Exnr.1999.7241  1
2000 Baloh RH, Enomoto H, Johnson EM, Milbrandt J. The GDNF family ligands and receptors - implications for neural development. Current Opinion in Neurobiology. 10: 103-10. PMID 10679429 DOI: 10.1016/S0959-4388(99)00048-3  1
2000 Baloh RH, Tansey MG, Johnson EM, Milbrandt J. Functional mapping of receptor specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRalpha1 RET-specific agonists. The Journal of Biological Chemistry. 275: 3412-20. PMID 10652334 DOI: 10.1074/Jbc.275.5.3412  1
2000 Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRα-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival Neuron. 25: 611-623.  1
2000 Deshmukh M, Johnson EM. 8. Apoptosis Facts, Research and Intervention in Geriatrics. 2000: 129-142.  1
1999 Leitner ML, Molliver DC, Osborne PA, Vejsada R, Golden JP, Lampe PA, Kato AC, Milbrandt J, Johnson EM. Analysis of the retrograde transport of glial cell line-derived neurotrophic factor (GDNF), neurturin, and persephin suggests that in vivo signaling for the GDNF family is GFRalpha coreceptor-specific. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9322-31. PMID 10531437 DOI: 10.1523/Jneurosci.19-21-09322.1999  1
1999 Selznick LA, Holtzman DM, Han BH, Gökden M, Srinivasan AN, Johnson EM, Roth KA. In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 1020-6. PMID 10499444 DOI: 10.1097/00005072-199909000-00012  1
1999 Hashino E, Johnson EM, Milbrandt J, Shero M, Salvi RJ, Cohan CS. Multiple actions of neurturin correlate with spatiotemporal patterns of Ret expression in developing chick cranial ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8476-86. PMID 10493748 DOI: 10.1523/Jneurosci.19-19-08476.1999  1
1999 Putcha GV, Deshmukh M, Johnson EM. BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7476-85. PMID 10460254 DOI: 10.1523/Jneurosci.19-17-07476.1999  1
1999 Golden JP, DeMaro JA, Osborne PA, Milbrandt J, Johnson EM. Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse. Experimental Neurology. 158: 504-28. PMID 10415156 DOI: 10.1006/Exnr.1999.7127  1
1999 Davies JA, Millar CB, Johnson EM, Milbrandt J. Neurturin: an autocrine regulator of renal collecting duct development. Developmental Genetics. 24: 284-92. PMID 10322636 DOI: 10.1002/(Sici)1520-6408(1999)24:3/4<284::Aid-Dvg11>3.0.Co;2-X  1
1999 Heuckeroth RO, Enomoto H, Grider JR, Golden JP, Hanke JA, Jackman A, Molliver DC, Bardgett ME, Snider WD, Johnson EM, Milbrandt J. Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron. 22: 253-63. PMID 10069332 DOI: 10.1016/S0896-6273(00)81087-9  1
1999 Moulder KL, Narita M, Chang LK, Bu G, Johnson EM. Analysis of a novel mechanism of neuronal toxicity produced by an apolipoprotein E-derived peptide. Journal of Neurochemistry. 72: 1069-80. PMID 10037478 DOI: 10.1046/J.1471-4159.1999.0721069.X  1
1999 Moulder KL, Onodera O, Burke JR, Strittmatter WJ, Johnson EM. Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 705-15. PMID 9880591 DOI: 10.1523/Jneurosci.19-02-00705.1999  1
1998 Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML, Araki T, Johnson EM, Milbrandt J. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron. 21: 1291-302. PMID 9883723 DOI: 10.1016/S0896-6273(00)80649-2  1
1998 Deshmukh M, Johnson EM. Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron. 21: 695-705. PMID 9808457 DOI: 10.1016/S0896-6273(00)80587-5  1
1998 Franklin JL, Johnson EM. Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis. The Journal of Cell Biology. 142: 1313-24. PMID 9732291 DOI: 10.1083/Jcb.142.5.1313  1
1998 Enomoto H, Araki T, Jackman A, Heuckeroth RO, Snider WD, Johnson EM, Milbrandt J. GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron. 21: 317-24. PMID 9728913 DOI: 10.1016/S0896-6273(00)80541-3  1
1998 Golden JP, Baloh RH, Kotzbauer PT, Lampe PA, Osborne PA, Milbrandt J, Johnson EM. Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. The Journal of Comparative Neurology. 398: 139-50. PMID 9703032 DOI: 10.1002/(Sici)1096-9861(19980817)398:1<139::Aid-Cne9>3.0.Co;2-2  1
1998 Heuckeroth RO, Lampe PA, Johnson EM, Milbrandt J. Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro. Developmental Biology. 200: 116-29. PMID 9698461 DOI: 10.1006/Dbio.1998.8955  1
1998 Easton RM, Johnson EM, Creedon DJ. Analysis of events leading to neuronal death after infection with E1-deficient adenoviral vectors. Molecular and Cellular Neurosciences. 11: 334-47. PMID 9698398 DOI: 10.1006/Mcne.1998.0690  1
1998 Deckwerth TL, Easton RM, Knudson CM, Korsmeyer SJ, Johnson EM. Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation. Experimental Neurology. 152: 150-62. PMID 9682022 DOI: 10.1006/Exnr.1998.6846  1
1998 Horger BA, Nishimura MC, Armanini MP, Wang LC, Poulsen KT, Rosenblad C, Kirik D, Moffat B, Simmons L, Johnson E, Milbrandt J, Rosenthal A, Bjorklund A, Vandlen RA, Hynes MA, et al. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4929-37. PMID 9634558 DOI: 10.1523/Jneurosci.18-13-04929.1998  1
1998 Rodig SJ, Meraz MA, White JM, Lampe PA, Riley JK, Arthur CD, King KL, Sheehan KC, Yin L, Pennica D, Johnson EM, Schreiber RD. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell. 93: 373-83. PMID 9590172 DOI: 10.1016/S0092-8674(00)81166-6  1
1998 Baloh RH, Gorodinsky A, Golden JP, Tansey MG, Keck CL, Popescu NC, Johnson EM, Milbrandt J. GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. Proceedings of the National Academy of Sciences of the United States of America. 95: 5801-6. PMID 9576965 DOI: 10.1073/Pnas.95.10.5801  1
1998 Cheng Y, Deshmukh M, D'Costa A, Demaro JA, Gidday JM, Shah A, Sun Y, Jacquin MF, Johnson EM, Holtzman DM. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. The Journal of Clinical Investigation. 101: 1992-9. PMID 9576764 DOI: 10.1172/Jci2169  1
1998 Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, ... ... Johnson EM, et al. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron. 20: 245-53. PMID 9491986 DOI: 10.1016/S0896-6273(00)80453-5  1
1997 Easton RM, Deckwerth TL, Parsadanian AS, Johnson EM. Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9656-66. PMID 9391020 DOI: 10.1523/Jneurosci.17-24-09656.1997  1
1997 Miller TM, Moulder KL, Knudson CM, Creedon DJ, Deshmukh M, Korsmeyer SJ, Johnson EM. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. The Journal of Cell Biology. 139: 205-17. PMID 9314540 DOI: 10.1083/Jcb.139.1.205  1
1997 Heuckeroth RO, Kotzbauer P, Copeland NG, Gilbert DJ, Jenkins NA, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3. Genomics. 44: 137-40. PMID 9286710 DOI: 10.1006/Geno.1997.4846  1
1997 Hill JM, Garza HH, Helmy MF, Cook SD, Osborne PA, Johnson EM, Thompson HW, Green LC, O'Callaghan RJ, Gebhardt BM. Nerve growth factor antibody stimulates reactivation of ocular herpes simplex virus type 1 in latently infected rabbits. Journal of Neurovirology. 3: 206-11. PMID 9200068 DOI: 10.3109/13550289709018295  1
1997 Creedon DJ, Tansey MG, Baloh RH, Osborne PA, Lampe PA, Fahrner TJ, Heuckeroth RO, Milbrandt J, Johnson EM. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 7018-23. PMID 9192684 DOI: 10.1073/Pnas.94.13.7018  1
1997 Deshmukh M, Johnson EM. Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Molecular Pharmacology. 51: 897-906. PMID 9187255 DOI: 10.1124/Mol.51.6.897  1
1997 Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron. 18: 793-802. PMID 9182803 DOI: 10.1016/S0896-6273(00)80318-9  1
1997 Dugan LL, Creedon DJ, Johnson EM, Holtzman DM. Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway Proceedings of the National Academy of Sciences of the United States of America. 94: 4086-4091. PMID 9108109 DOI: 10.1073/Pnas.94.8.4086  1
1997 Miller TM, Tansey MG, Johnson EM, Creedon DJ. Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells Journal of Biological Chemistry. 272: 9847-9853. PMID 9092520 DOI: 10.1074/Jbc.272.15.9847  1
1996 Deshmukh M, Vasilakos J, Deckwerth TL, Lampe PA, Shivers BD, Johnson EM. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. The Journal of Cell Biology. 135: 1341-54. PMID 8947555 DOI: 10.1083/Jcb.135.5.1341  1
1996 Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM, Milbrandt J. Neurturin, a relative of glial-cell-line-derived neurotrophic factor Nature. 384: 467-470. PMID 8945474 DOI: 10.1038/384467A0  1
1996 Johnson EM, Deckwerth TL, Deshmukh M. Neuronal death in developmental models: possible implications in neuropathology. Brain Pathology (Zurich, Switzerland). 6: 397-409. PMID 8944313 DOI: 10.1111/J.1750-3639.1996.Tb00872.X  1
1996 Miller TM, Johnson EM. Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells Journal of Neuroscience. 16: 7487-7495. PMID 8922404 DOI: 10.1523/Jneurosci.16-23-07487.1996  1
1996 Bullock ED, Johnson EM. Nerve growth factor induces the expression of certain cytokine genes and bcl-2 in mast cells: Potential role in survival promotion Journal of Biological Chemistry. 271: 27500-27508. PMID 8910334 DOI: 10.1074/Jbc.271.44.27500  1
1996 Deckwerth TL, Elliott JL, Knudson CM, Johnson EM, Snider WD, Korsmeyer SJ. BAX is required for neuronal death after trophic factor deprivation and during development. Neuron. 17: 401-11. PMID 8816704 DOI: 10.1016/S0896-6273(00)80173-7  1
1996 Creedon DJ, Johnson EM, Lawrence JC. Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival. The Journal of Biological Chemistry. 271: 20713-8. PMID 8702822 DOI: 10.1074/Jbc.271.34.20713  1
1995 Johnson EM, Greenlund LJ, Akins PT, Hsu CY. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury. Journal of Neurotrauma. 12: 843-52. PMID 8594212 DOI: 10.1089/Neu.1995.12.843  1
1995 Silos-Santiago I, Greenlund LJ, Johnson EM, Snider WD. Molecular genetics of neuronal survival. Current Opinion in Neurobiology. 5: 42-9. PMID 7773004 DOI: 10.1016/0959-4388(95)80085-9  1
1995 Lampe PA, Cornbrooks EB, Juhasz A, Johnson EM, Franklin JL. Suppression of programmed neuronal death by a thapsigargin-induced Ca2+ influx. Journal of Neurobiology. 26: 205-12. PMID 7707042 DOI: 10.1002/Neu.480260205  1
1994 Kotzbauer PT, Lampe PA, Estus S, Milbrandt J, Johnson EM. Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor Neuron. 12: 763-773. PMID 8161448 DOI: 10.1016/0896-6273(94)90329-8  1
1994 Freeman RS, Estus S, Johnson EM. Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death. Neuron. 12: 343-55. PMID 8110463 DOI: 10.1016/0896-6273(94)90276-3  1
1994 Laycock KA, Brady RH, Lee SF, Osborne PA, Johnson EM, Pepose JS. The role of nerve growth factor in modulating herpes simplex virus reactivation in vivo Graefe's Archive For Clinical and Experimental Ophthalmology. 232: 421-425. PMID 7926874 DOI: 10.1007/Bf00186584  1
1994 Franklin JL, Johnson EM. Elevated intracellular calcium blocks programmed neuronal death. Annals of the New York Academy of Sciences. 747: 195-204. PMID 7847671 DOI: 10.1111/J.1749-6632.1994.Tb44410.X  1
1994 Franklin JL, Johnson EM. Block of neuronal apoptosis by a sustained increase of steady-state free Ca2+ concentration. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 251-6. PMID 7846122 DOI: 10.1098/Rstb.1994.0102  1
1994 Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM. Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. The Journal of Cell Biology. 127: 1717-27. PMID 7798322 DOI: 10.1083/Jcb.127.6.1717  1
1994 Johnson EM. Possible role of neuronal apoptosis in Alzheimer's disease Neurobiology of Aging. 15: 187-189. PMID 7700450 DOI: 10.1016/0197-4580(94)90202-X  1
1993 Smith CJ, Johnson EM, Osborne P, Freeman RS, Neveu I, Brachet P. NGF deprivation and neuronal degeneration trigger altered beta-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro. Brain Research. Molecular Brain Research. 17: 328-34. PMID 8510504 DOI: 10.1016/0169-328X(93)90018-K  1
1993 Johnson EM, Deckwerth TL. Molecular mechanisms of developmental neuronal death Annual Review of Neuroscience. 16: 31-46. PMID 8460896 DOI: 10.1146/ANNUREV.NE.16.030193.000335  1
1993 Freeman RS, Estus S, Horigome K, Johnson EM. Cell death genes in invertebrates and (maybe) vertebrates. Current Opinion in Neurobiology. 3: 25-31. PMID 8453285 DOI: 10.1016/0959-4388(93)90031-S  1
1993 Henderson TA, Rhoades RW, Bennett-Clarke CA, Osborne PA, Johnson EM, Jacquin MF. NGF augmentation rescues trigeminal ganglion and principalis neurons, but not brainstem or cortical whisker patterns, after infraorbital nerve injury at birth Journal of Comparative Neurology. 336: 243-260. PMID 8245217 DOI: 10.1002/Cne.903360207  1
1992 Franklin JL, Johnson EM. Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends in Neurosciences. 15: 501-8. PMID 1282751 DOI: 10.1016/0166-2236(92)90103-F  1
1991 Ferguson IA, Schweitzer JB, Bartlett PF, Johnson EM. Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors. The Journal of Comparative Neurology. 313: 680-92. PMID 1664436 DOI: 10.1002/Cne.903130411  1
1990 Ruit KG, Osborne PA, Schmidt RE, Johnson EM, Snider WD. Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2412-9. PMID 2376779 DOI: 10.1523/Jneurosci.10-07-02412.1990  1
1990 Wanaka A, Johnson EM. Developmental study of nerve growth factor receptor mRNA expression in the postnatal rat cerebellum. Brain Research. Developmental Brain Research. 55: 288-92. PMID 2174751 DOI: 10.1016/0165-3806(90)90211-G  1
1990 Wanaka A, Johnson EM, Milbrandt J. Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron. 5: 267-81. PMID 2169267 DOI: 10.1016/0896-6273(90)90164-B  1
1990 Yan Q, Clark HB, Johnson EM. Nerve growth factor receptor in neural lobe of rat pituitary gland: immunohistochemical localization, biochemical characterization and regulation. Journal of Neurocytology. 19: 302-12. PMID 2167948 DOI: 10.1007/Bf01188400  1
1989 Snider WD, Johnson EM. Neurotrophic molecules. Annals of Neurology. 26: 489-506. PMID 2684002 DOI: 10.1002/ana.410260402  1
1989 Johnson EM, Osborne PA, Taniuchi M. Destruction of sympathetic and sensory neurons in the developing rat by a monoclonal antibody against the nerve growth factor (NGF) receptor Brain Research. 478: 166-170. PMID 2538200 DOI: 10.1016/0006-8993(89)91491-1  1
1988 Laing NG, Osborne PA, Johnson EM. Muscle spindle number is normal in guinea pigs with reduced dorsal root ganglia following in utero deprivation of nerve growth factor Brain Research. 444: 351-355. PMID 2965960 DOI: 10.1016/0006-8993(88)90945-6  1
1988 Johnson EM. Regulation of nerve growth factor receptor expression on Schwann cells Progress in Brain Research. 78: 327-331. PMID 2854638 DOI: 10.1016/S0079-6123(08)60300-3  1
1988 DiStefano PS, Johnson EM. Identification of a truncated form of the nerve growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 270-4. PMID 2829174 DOI: 10.1073/Pnas.85.1.270  1
1988 DiStefano PS, Johnson EM. Nerve growth factor receptors on cultured rat Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 231-41. PMID 2828562 DOI: 10.1523/Jneurosci.08-01-00231.1988  1
1988 Yan Q, Snider WD, Pinzone JJ, Johnson EM. Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: assessment of potential neurotrophic effects. Neuron. 1: 335-43. PMID 2483324 DOI: 10.1016/0896-6273(88)90082-7  1
1988 Johnson EM, Taniuchi M, DiStefano PS. Expression and possible function of nerve growth factor receptors on Schwann cells. Trends in Neurosciences. 11: 299-304. PMID 2465632 DOI: 10.1016/0166-2236(88)90090-2  1
1988 Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. The Journal of Cell Biology. 106: 829-44. PMID 2450099 DOI: 10.1083/Jcb.106.3.829  1
1987 Rich KM, Luszczynski JR, Osborne PA, Johnson EM. Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury Journal of Neurocytology. 16: 261-268. PMID 3625240 DOI: 10.1007/Bf01795309  1
1987 Wallace TL, Johnson EM. Partial purification of a parasympathetic neurotrophic factor in pig lung. Brain Research. 411: 351-63. PMID 3607439 DOI: 10.1016/0006-8993(87)91087-0  1
1986 Wallace TL, Johnson EM. Characterization of choline acetyltransferase-sustaining and survival-promoting activities for parasympathetic neurons in pig lung. Brain Research. 375: 92-101. PMID 3719361 DOI: 10.1016/0006-8993(86)90962-5  1
1986 Sikich L, Woolsey TA, Johnson EM. Effect of a uniform partial denervation of the periphery on the peripheral and central vibrissal system in guinea pigs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1227-40. PMID 3711979 DOI: 10.1523/Jneurosci.06-05-01227.1986  1
1986 Taniuchi M, Clark HB, Johnson EM. Induction of nerve growth factor receptor in Schwann cells after axotomy. Proceedings of the National Academy of Sciences of the United States of America. 83: 4094-8. PMID 3012551 DOI: 10.1073/Pnas.83.11.4094  1
1986 Taniuchi M, Schweitzer JB, Johnson EM. Nerve growth factor receptor molecules in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 83: 1950-4. PMID 2419914 DOI: 10.1073/Pnas.83.6.1950  0.36
1986 Johnson EM, Rich KM, Yip HK. The role of NGF in sensory neurons in vivo Trends in Neurosciences. 9: 33-37. DOI: 10.1016/0166-2236(86)90012-3  1
1985 Rich KM, Johnson EM. Ventral rhizotomy enhances regeneration of uninjured sensory neurons Brain Research. 335: 182-187. PMID 4039959 DOI: 10.1016/0006-8993(85)90292-6  1
1985 McDougal DB, McDougal SH, Johnson EM. Effect of capsaicin upon fluoride sensitive acid phosphatases in selected ganglia and spinal cord and upon neuronal size and number in dorsal root ganglion Brain Research. 331: 63-70. PMID 3986564 DOI: 10.1016/0006-8993(85)90715-2  1
1985 DiStefano PS, Schweitzer JB, Taniuchi M, Johnson EM. Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor. The Journal of Cell Biology. 101: 1107-14. PMID 2993314 DOI: 10.1083/Jcb.101.3.1107  1
1984 Rich KM, Yip HK, Osborne PA, Schmidt RE, Johnson EM. Role of nerve growth factor in the adult dorsal root ganglia neuron and its response to injury Journal of Comparative Neurology. 230: 110-118. PMID 6392356 DOI: 10.1002/Cne.902300110  1
1983 Johnson EM, Osborne PA, Rydel RE, Schmdt RE, Pearson J. Characterization of the effects of autoimmune nerve growth factor deprivation in the developing guinea-pig Neuroscience. 8: 631-642. PMID 6856089 DOI: 10.1016/0306-4522(83)90204-X  1
1983 Pearson J, Johnson EM, Brandeis L. Effects of antibodies to nerve growth factor on intrauterine development of derivatives of cranial neural crest and placode in the guinea pig Developmental Biology. 96: 32-36. PMID 6825957 DOI: 10.1016/0012-1606(83)90308-1  1
1982 Bell J, Gruenthal M, Finger S, Lundberg P, Johnson E. Behavioral effects of early deprivation of nerve growth factor: Some similarities with familial dysautonomia Brain Research. 234: 409-421. PMID 7059836 DOI: 10.1016/0006-8993(82)90880-0  1
1982 Kornblum HI, Johnson EM. Time and dose dependencies of effects of nerve growth factor on sympathetic and sensory neurons in neonatal rats. Brain Research. 234: 41-51. PMID 7059824 DOI: 10.1016/0006-8993(82)90471-1  1
1982 Johnson EM, Gorin PD, Osborne PA, Rydel RE, Pearson J. Effects of autoimmune NGF deprivation in the adult rabbit and offspring Brain Research. 240: 131-140. PMID 6124306 DOI: 10.1016/0006-8993(82)90650-3  1
1980 Johnson EM, Taylor AS. Inhibition of S-adenosyl methionine decarboxylase by guanethidine. Biochemical Pharmacology. 29: 113-5. PMID 7362620 DOI: 10.1016/0006-2952(80)90253-1  1
1979 Gorin P, Johnson EM. Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons Proceedings of the National Academy of Sciences of the United States of America. 76: 5382-5386. PMID 92024 DOI: 10.1073/Pnas.76.10.5382  1
1979 Johnson EM, Hunter FE. Chemical sympathectomy by guanidinium adrenergic neuron blocking agents Federation Proceedings. 38. DOI: 10.1016/0006-2952(79)90468-4  1
1978 Johnson EM. Destruction of the sympathetic nervous system in neonatal rats and hamsters by vinblastine: prevention by concomitant administration of nerve growth factor Brain Research. 141: 105-118. PMID 75043 DOI: 10.1016/0006-8993(78)90620-0  1
1976 Douglas JR, Johnson EM, Heist JF, Marshall GR, Needleman P. Is the peripheral sympatho-adrenal nervous system necessary for renal hypertension? The Journal of Pharmacology and Experimental Therapeutics. 196: 35-43. PMID 1246014  1
1975 Douglas JR, Johnson EM, Marshall GR, Heist J, Hartman BK, Needleman P. Development and maintenance of renal hypertension in normal and guanethidine sympathectomized rats. Circulation Research. 36: 171-8. PMID 1093753 DOI: 10.1161/01.Res.36.6.171  1
1974 Johnson EM, Marshall GR, Needleman P. Modification of responses to sympathetic nerve stimulation by the renin-angiotensin system in rats. British Journal of Pharmacology. 51: 541-7. PMID 4375530 DOI: 10.1111/J.1476-5381.1974.Tb09672.X  1
1974 Needleman P, Marshall GR, Johnson EM. Determinants and modification of adrenergic and vascular resistance in the kidney. The American Journal of Physiology. 227: 665-9. PMID 4369912 DOI: 10.1152/ajplegacy.1974.227.3.665  1
1974 Needleman P, Douglas JR, Jakschik B, Stoecklein PB, Johnson EM. Release of renal prostaglandin by catecholamines: relationship to renal endocrine function. The Journal of Pharmacology and Experimental Therapeutics. 188: 453-60. PMID 4359555  1
1973 Ferrendelli JA, Johnson EM, Chang M, Needleman P. Inhibition of brain adenylate cyclase by ethacrynic acid and dithiobisnitrobenzoic acid. Biochemical Pharmacology. 22: 3133-6. PMID 4761572 DOI: 10.1016/0006-2952(73)90206-2  1
1973 Johnson EM, Lang S, Needleman P. Dissociation of sympathetic compensation from glyceryl trinitrate tolerance. European Journal of Pharmacology. 21: 189-94. PMID 4633119 DOI: 10.1016/0014-2999(73)90225-2  1
1973 Needleman P, Johnson EM. Mechanism of tolerance development to organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 184: 709-15. PMID 4631470  1
1973 Frazier WA, Ohlendorf CE, Boyd LF, Aloe L, Johnson EM, Ferrendelli JA, Bradshaw RA. Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth in embryonic chick sensory ganglia: demonstration of independent pathways of stimulation. Proceedings of the National Academy of Sciences of the United States of America. 70: 2448-52. PMID 4365380 DOI: 10.1073/Pnas.70.8.2448  1
1973 Needleman P, Kauffman AH, Douglas JR, Johnson EM, Marshall GR. Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs. The American Journal of Physiology. 224: 1415-9. PMID 4351298 DOI: 10.1152/ajplegacy.1973.224.6.1415  1
1973 Douglas JR, Johnson EM, Marshall GR, Jaffe BM, Needleman P. Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII. Prostaglandins. 3: 67-74. PMID 4348364 DOI: 10.1016/0090-6980(73)90138-X  1
1973 Needleman P, Jakschik B, Johnson EM. Sulfhydryl requirement for relaxation of vascular smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. 187: 324-31. PMID 4201275  1
1972 Johnson EM, Harkey AB, Blehm DJ, Needleman P. Clearance and metabolism of organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 182: 56-62. PMID 4625289  1
1972 Needleman P, Lang S, Johnson EM. Organic nitrates: relationship between biotransformation and rational angina pectoris therapy. The Journal of Pharmacology and Experimental Therapeutics. 181: 489-97. PMID 4624401  1
1972 Lang S, Johnson EM, Needleman P. Metabolism of and vascular responses to glyceryl trinitrate in the eviscerated rat. Biochemical Pharmacology. 21: 422-4. PMID 4622561 DOI: 10.1016/0006-2952(72)90356-5  1
1972 Blaustein MP, Johnson EM, Needleman P. Calcium-dependent norepinephrine release from presynaptic nerve endings in vitro. Proceedings of the National Academy of Sciences of the United States of America. 69: 2237-40. PMID 4506092 DOI: 10.1073/Pnas.69.8.2237  1
1972 Needleman P, Johnson EM, Vine W, Flanigan E, Marshall GR. Pharmacology of antagonists of angiotensin I and II. Circulation Research. 31: 862-7. PMID 4345101 DOI: 10.1161/01.Res.31.6.862  1
1971 Needleman P, Blehm DJ, Harkey AB, Johnson EM, Lang S. The metabolic pathway in the degradation of glyceryl trinitrate. The Journal of Pharmacology and Experimental Therapeutics. 179: 347-53. PMID 5002725  1
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