Year |
Citation |
Score |
2015 |
Bartus RT, Kordower JH, Johnson EM, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies. Neurobiology of Disease. 78: 162-71. PMID 25841760 DOI: 10.1016/J.Nbd.2015.03.023 |
0.322 |
|
2013 |
Golden JP, Demaro JA, Knoten A, Hoshi M, Pehek E, Johnson EM, Gereau RW, Jain S. Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17095-107. PMID 24155314 DOI: 10.1523/Jneurosci.0890-13.2013 |
0.312 |
|
2013 |
Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM, Bartus RT. Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiology of Disease. 58: 38-48. PMID 23631873 DOI: 10.1016/J.Nbd.2013.04.011 |
0.646 |
|
2011 |
Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Siffert J, Johnson EM, Olanow CW, Mufson EJ, Kordower JH. Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 27-36. PMID 21322017 DOI: 10.1002/Mds.23442 |
0.358 |
|
2010 |
Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RW, Johnson EM, Jain S. RET signaling is required for survival and normal function of nonpeptidergic nociceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3983-94. PMID 20237269 DOI: 10.1523/Jneurosci.5930-09.2010 |
0.334 |
|
2008 |
Wang LH, Johnson EM. Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease. Neurology. 71: 462; author reply 46. PMID 18678833 DOI: 10.1212/01.Wnl.0000324506.93877.5E |
0.457 |
|
2008 |
Encinas M, Rozen EJ, Dolcet X, Jain S, Comella JX, Milbrandt J, Johnson EM. Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death and Differentiation. 15: 1510-21. PMID 18497757 DOI: 10.1038/Cdd.2008.76 |
0.452 |
|
2008 |
Brantley MA, Jain S, Barr EE, Johnson EM, Milbrandt J. Neurturin-mediated ret activation is required for retinal function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4123-35. PMID 18417692 DOI: 10.1523/Jneurosci.0249-08.2008 |
0.315 |
|
2007 |
Gustin JA, Yang M, Johnson EM, Milbrandt J. Deciphering adaptor specificity in GFL-dependent RET-mediated proliferation and neurite outgrowth. Journal of Neurochemistry. 102: 1184-94. PMID 17663753 DOI: 10.1111/J.1471-4159.2007.04624.X |
0.364 |
|
2007 |
Pierchala BA, Tsui CC, Milbrandt J, Johnson EM. NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation. Journal of Neurochemistry. 100: 1169-76. PMID 17241133 DOI: 10.1111/J.1471-4159.2006.04292.X |
0.754 |
|
2006 |
Jain S, Golden JP, Wozniak D, Pehek E, Johnson EM, Milbrandt J. RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11230-8. PMID 17065462 DOI: 10.1523/Jneurosci.1876-06.2006 |
0.402 |
|
2006 |
Besirli CG, Johnson EM. The activation loop phosphorylation of protein kinase D is an early marker of neuronal DNA damage. Journal of Neurochemistry. 99: 218-25. PMID 16911582 DOI: 10.1111/J.1471-4159.2006.04116.X |
0.41 |
|
2006 |
Pierchala BA, Milbrandt J, Johnson EM. Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2777-87. PMID 16525057 DOI: 10.1523/Jneurosci.3420-05.2006 |
0.72 |
|
2005 |
Besirli CG, Wagner EF, Johnson EM. The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. The Journal of Cell Biology. 170: 401-11. PMID 16061693 DOI: 10.1083/Jcb.200501138 |
0.473 |
|
2005 |
Wei L, Cui L, Snider BJ, Rivkin M, Yu SS, Lee CS, Adams LD, Gottlieb DI, Johnson EM, Yu SP, Choi DW. Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiology of Disease. 19: 183-93. PMID 15837573 DOI: 10.1016/J.Nbd.2004.12.016 |
0.338 |
|
2005 |
Leitner ML, Wang LH, Osborne PA, Golden JP, Milbrandt J, Johnson EM. Expression and function of GDNF family ligands and receptors in the carotid body. Experimental Neurology. 191: S68-79. PMID 15629763 DOI: 10.1016/J.Expneurol.2004.08.013 |
0.326 |
|
2005 |
Lee CS, Tee LY, Dusenbery S, Takata T, Golden JP, Pierchala BA, Gottlieb DI, Johnson EM, Choi DW, Snider BJ. Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells. Experimental Neurology. 191: 65-76. PMID 15589513 DOI: 10.1016/J.Expneurol.2004.08.025 |
0.751 |
|
2005 |
Wang LH, Paden AJ, Johnson EM. Mixed-lineage kinase inhibitors require the activation of Trk receptors to maintain long-term neuronal trophism and survival. The Journal of Pharmacology and Experimental Therapeutics. 312: 1007-19. PMID 15525794 DOI: 10.1124/Jpet.104.077800 |
0.454 |
|
2004 |
Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J. GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 44: 623-36. PMID 15541311 DOI: 10.1016/J.Neuron.2004.10.032 |
0.399 |
|
2004 |
Jain S, Naughton CK, Yang M, Strickland A, Vij K, Encinas M, Golden J, Gupta A, Heuckeroth R, Johnson EM, Milbrandt J. Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis. Development (Cambridge, England). 131: 5503-13. PMID 15469971 DOI: 10.1242/Dev.01421 |
0.32 |
|
2004 |
Crowder RJ, Enomoto H, Yang M, Johnson EM, Milbrandt J. Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth. The Journal of Biological Chemistry. 279: 42072-81. PMID 15286081 DOI: 10.1074/Jbc.M403726200 |
0.366 |
|
2004 |
Pierchala BA, Ahrens RC, Paden AJ, Johnson EM. Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways. The Journal of Biological Chemistry. 279: 27986-93. PMID 15117960 DOI: 10.1074/Jbc.M312237200 |
0.769 |
|
2004 |
Encinas M, Crowder RJ, Milbrandt J, Johnson EM. Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. The Journal of Biological Chemistry. 279: 18262-9. PMID 14766744 DOI: 10.1074/Jbc.M400505200 |
0.447 |
|
2004 |
Wang LH, Besirli CG, Johnson EM. Mixed-lineage kinases: a target for the prevention of neurodegeneration. Annual Review of Pharmacology and Toxicology. 44: 451-74. PMID 14744254 DOI: 10.1146/Annurev.Pharmtox.44.101802.121840 |
0.466 |
|
2004 |
Putcha GV, Johnson EM. Men are but worms: neuronal cell death in C elegans and vertebrates. Cell Death and Differentiation. 11: 38-48. PMID 14647239 DOI: 10.1038/Sj.Cdd.4401352 |
0.459 |
|
2003 |
Golden JP, Milbrandt J, Johnson EM. Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. Experimental Neurology. 184: 447-55. PMID 14637114 DOI: 10.1016/J.Expneurol.2003.07.999 |
0.498 |
|
2003 |
Besirli CG, Deckwerth TL, Crowder RJ, Freeman RS, Johnson EM. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death and Differentiation. 10: 1045-58. PMID 12934079 DOI: 10.1038/Sj.Cdd.4401259 |
0.632 |
|
2003 |
Chang LK, Schmidt RE, Johnson EM. Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death. The Journal of Cell Biology. 162: 245-56. PMID 12876275 DOI: 10.1083/Jcb.200302109 |
0.43 |
|
2003 |
Putcha GV, Le S, Frank S, Besirli CG, Clark K, Chu B, Alix S, Youle RJ, LaMarche A, Maroney AC, Johnson EM. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron. 38: 899-914. PMID 12818176 DOI: 10.1016/S0896-6273(03)00355-6 |
0.328 |
|
2003 |
Besirli CG, Johnson EM. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents. The Journal of Biological Chemistry. 278: 22357-66. PMID 12684520 DOI: 10.1074/Jbc.M300742200 |
0.415 |
|
2002 |
Harris C, Maroney AC, Johnson EM. Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis. Journal of Neurochemistry. 83: 992-1001. PMID 12421372 DOI: 10.1046/J.1471-4159.2002.01219.X |
0.45 |
|
2002 |
Deshmukh M, Du C, Wang X, Johnson EM. Exogenous smac induces competence and permits caspase activation in sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8018-27. PMID 12223555 DOI: 10.1523/Jneurosci.22-18-08018.2002 |
0.656 |
|
2002 |
Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J. Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 35: 267-82. PMID 12160745 DOI: 10.1016/S0896-6273(02)00774-2 |
0.335 |
|
2002 |
Tsui-Pierchala BA, Encinas M, Milbrandt J, Johnson EM. Lipid rafts in neuronal signaling and function. Trends in Neurosciences. 25: 412-7. PMID 12127758 DOI: 10.1016/S0166-2236(02)02215-4 |
0.374 |
|
2002 |
Tsui-Pierchala BA, Ahrens RC, Crowder RJ, Milbrandt J, Johnson EM. The long and short isoforms of Ret function as independent signaling complexes. The Journal of Biological Chemistry. 277: 34618-25. PMID 12091387 DOI: 10.1074/Jbc.M203580200 |
0.442 |
|
2002 |
Chang LK, Putcha GV, Deshmukh M, Johnson EM. Mitochondrial involvement in the point of no return in neuronal apoptosis. Biochimie. 84: 223-31. PMID 12022953 DOI: 10.1016/S0300-9084(02)01372-X |
0.599 |
|
2002 |
Chang LK, Johnson EM. Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition. The Journal of Cell Biology. 157: 771-81. PMID 12021257 DOI: 10.1083/Jcb.200112130 |
0.484 |
|
2002 |
Rakowicz WP, Staples CS, Milbrandt J, Brunstrom JE, Johnson EM. Glial cell line-derived neurotrophic factor promotes the survival of early postnatal spinal motor neurons in the lateral and medial motor columns in slice culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3953-62. PMID 12019314 DOI: 10.1523/Jneurosci.22-10-03953.2002 |
0.448 |
|
2002 |
Putcha GV, Harris CA, Moulder KL, Easton RM, Thompson CB, Johnson EM. Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice. The Journal of Cell Biology. 157: 441-53. PMID 11980919 DOI: 10.1083/Jcb.200110108 |
0.472 |
|
2002 |
Zhou Y, Zhang W, Easton R, Ray JW, Lampe P, Jiang Z, Brunkan AL, Goate A, Johnson EM, Wu JY. Presenilin-1 protects against neuronal apoptosis caused by its interacting protein PAG. Neurobiology of Disease. 9: 126-38. PMID 11895366 DOI: 10.1006/Nbdi.2001.0472 |
0.459 |
|
2002 |
Tsui-Pierchala BA, Milbrandt J, Johnson EM. NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons. Neuron. 33: 261-73. PMID 11804573 DOI: 10.1016/S0896-6273(01)00585-2 |
0.487 |
|
2002 |
Xia S, Lampe PA, Deshmukh M, Yang A, Brown BS, Rothman SM, Johnson EM, Yu SP. Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 114-22. PMID 11756494 DOI: 10.1523/Jneurosci.22-01-00114.2002 |
0.562 |
|
2002 |
Harris CA, Deshmukh M, Tsui-Pierchala B, Maroney AC, Johnson EM. Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 103-13. PMID 11756493 DOI: 10.1523/Jneurosci.22-01-00103.2002 |
0.631 |
|
2001 |
Harris CA, Johnson EM. BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. The Journal of Biological Chemistry. 276: 37754-60. PMID 11495903 DOI: 10.1074/Jbc.M104073200 |
0.42 |
|
2001 |
Putcha GV, Moulder KL, Golden JP, Bouillet P, Adams JA, Strasser A, Johnson EM. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron. 29: 615-28. PMID 11301022 DOI: 10.1016/S0896-6273(01)00238-0 |
0.445 |
|
2001 |
Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM. c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1464-72. PMID 11222636 DOI: 10.1523/Jneurosci.21-05-01464.2001 |
0.659 |
|
2001 |
Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM. c-Src Is Required for Glial Cell Line-Derived Neurotrophic Factor (GDNF) Family Ligand-Mediated Neuronal Survival via a Phosphatidylinositol-3 Kinase (PI-3K)-Dependent Pathway The Journal of Neuroscience. 21: 1464-1472. DOI: 10.1523/JNEUROSCI.21-05-01464.2001 |
0.596 |
|
2000 |
Enomoto H, Heuckeroth RO, Golden JP, Johnson EM, Milbrandt J. Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Development (Cambridge, England). 127: 4877-89. PMID 11044402 |
0.381 |
|
2000 |
Tsui-Pierchala BA, Putcha GV, Johnson EM. Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7228-37. PMID 11007879 DOI: 10.1523/Jneurosci.20-19-07228.2000 |
0.479 |
|
2000 |
Hongo JA, Tsai SP, Moffat B, Schroeder KA, Jung C, Chuntharapai A, Lampe PA, Johnson EM, de Sauvage FJ, Armanini M, Phillips H, Devaux B. Characterization of novel neutralizing monoclonal antibodies specific to human neurturin. Hybridoma. 19: 303-15. PMID 11001403 DOI: 10.1089/027245700429855 |
0.368 |
|
2000 |
Deshmukh M, Kuida K, Johnson EM. Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization. The Journal of Cell Biology. 150: 131-43. PMID 10893262 DOI: 10.1083/Jcb.150.1.131 |
0.626 |
|
2000 |
Putcha GV, Deshmukh M, Johnson EM. Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation. The Journal of Cell Biology. 149: 1011-8. PMID 10831605 DOI: 10.1083/Jcb.149.5.1011 |
0.664 |
|
2000 |
Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron. 25: 611-23. PMID 10774729 DOI: 10.1016/S0896-6273(00)81064-8 |
0.595 |
|
2000 |
Deshmukh M, Johnson EM. Staurosporine-induced neuronal death: multiple mechanisms and methodological implications. Cell Death and Differentiation. 7: 250-61. PMID 10745270 DOI: 10.1038/Sj.Cdd.4400641 |
0.636 |
|
2000 |
Ho TW, Bristol LA, Coccia C, Li Y, Milbrandt J, Johnson E, Jin L, Bar-Peled O, Griffin JW, Rothstein JD. TGFbeta trophic factors differentially modulate motor axon outgrowth and protection from excitotoxicity. Experimental Neurology. 161: 664-75. PMID 10686085 DOI: 10.1006/Exnr.1999.7290 |
0.337 |
|
2000 |
Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM. Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Experimental Neurology. 161: 203-11. PMID 10683286 DOI: 10.1006/Exnr.1999.7241 |
0.658 |
|
2000 |
Baloh RH, Enomoto H, Johnson EM, Milbrandt J. The GDNF family ligands and receptors - implications for neural development. Current Opinion in Neurobiology. 10: 103-10. PMID 10679429 DOI: 10.1016/S0959-4388(99)00048-3 |
0.369 |
|
2000 |
Baloh RH, Tansey MG, Johnson EM, Milbrandt J. Functional mapping of receptor specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRalpha1 RET-specific agonists. The Journal of Biological Chemistry. 275: 3412-20. PMID 10652334 DOI: 10.1074/Jbc.275.5.3412 |
0.597 |
|
2000 |
Johnson EM, Deshmukh M. Mitochondrial status of caspase inhibitor-saved neurons: Role of membrane potential in commitment(s) to die Neurobiology of Aging. 21: 282. DOI: 10.1016/S0197-4580(00)83218-2 |
0.551 |
|
2000 |
Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRα-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival Neuron. 25: 611-623. |
0.579 |
|
2000 |
Deshmukh M, Johnson EM. 8. Apoptosis Facts, Research and Intervention in Geriatrics. 2000: 129-142. |
0.409 |
|
1999 |
Leitner ML, Molliver DC, Osborne PA, Vejsada R, Golden JP, Lampe PA, Kato AC, Milbrandt J, Johnson EM. Analysis of the retrograde transport of glial cell line-derived neurotrophic factor (GDNF), neurturin, and persephin suggests that in vivo signaling for the GDNF family is GFRalpha coreceptor-specific. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9322-31. PMID 10531437 DOI: 10.1523/Jneurosci.19-21-09322.1999 |
0.451 |
|
1999 |
Selznick LA, Holtzman DM, Han BH, Gökden M, Srinivasan AN, Johnson EM, Roth KA. In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 1020-6. PMID 10499444 DOI: 10.1097/00005072-199909000-00012 |
0.387 |
|
1999 |
Hashino E, Johnson EM, Milbrandt J, Shero M, Salvi RJ, Cohan CS. Multiple actions of neurturin correlate with spatiotemporal patterns of Ret expression in developing chick cranial ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8476-86. PMID 10493748 DOI: 10.1523/Jneurosci.19-19-08476.1999 |
0.416 |
|
1999 |
Putcha GV, Deshmukh M, Johnson EM. BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7476-85. PMID 10460254 DOI: 10.1523/Jneurosci.19-17-07476.1999 |
0.611 |
|
1999 |
Golden JP, DeMaro JA, Osborne PA, Milbrandt J, Johnson EM. Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse. Experimental Neurology. 158: 504-28. PMID 10415156 DOI: 10.1006/Exnr.1999.7127 |
0.37 |
|
1999 |
Heuckeroth RO, Enomoto H, Grider JR, Golden JP, Hanke JA, Jackman A, Molliver DC, Bardgett ME, Snider WD, Johnson EM, Milbrandt J. Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron. 22: 253-63. PMID 10069332 DOI: 10.1016/S0896-6273(00)81087-9 |
0.415 |
|
1999 |
Moulder KL, Narita M, Chang LK, Bu G, Johnson EM. Analysis of a novel mechanism of neuronal toxicity produced by an apolipoprotein E-derived peptide. Journal of Neurochemistry. 72: 1069-80. PMID 10037478 DOI: 10.1046/J.1471-4159.1999.0721069.X |
0.424 |
|
1999 |
Moulder KL, Onodera O, Burke JR, Strittmatter WJ, Johnson EM. Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 705-15. PMID 9880591 DOI: 10.1523/Jneurosci.19-02-00705.1999 |
0.379 |
|
1998 |
Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML, Araki T, Johnson EM, Milbrandt J. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron. 21: 1291-302. PMID 9883723 DOI: 10.1016/S0896-6273(00)80649-2 |
0.646 |
|
1998 |
Deshmukh M, Johnson EM. Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron. 21: 695-705. PMID 9808457 DOI: 10.1016/S0896-6273(00)80587-5 |
0.646 |
|
1998 |
Franklin JL, Johnson EM. Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis. The Journal of Cell Biology. 142: 1313-24. PMID 9732291 DOI: 10.1083/Jcb.142.5.1313 |
0.301 |
|
1998 |
Enomoto H, Araki T, Jackman A, Heuckeroth RO, Snider WD, Johnson EM, Milbrandt J. GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron. 21: 317-24. PMID 9728913 DOI: 10.1016/S0896-6273(00)80541-3 |
0.34 |
|
1998 |
Golden JP, Baloh RH, Kotzbauer PT, Lampe PA, Osborne PA, Milbrandt J, Johnson EM. Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. The Journal of Comparative Neurology. 398: 139-50. PMID 9703032 DOI: 10.1002/(Sici)1096-9861(19980817)398:1<139::Aid-Cne9>3.0.Co;2-2 |
0.431 |
|
1998 |
Heuckeroth RO, Lampe PA, Johnson EM, Milbrandt J. Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro. Developmental Biology. 200: 116-29. PMID 9698461 DOI: 10.1006/Dbio.1998.8955 |
0.498 |
|
1998 |
Easton RM, Johnson EM, Creedon DJ. Analysis of events leading to neuronal death after infection with E1-deficient adenoviral vectors. Molecular and Cellular Neurosciences. 11: 334-47. PMID 9698398 DOI: 10.1006/Mcne.1998.0690 |
0.415 |
|
1998 |
Deckwerth TL, Easton RM, Knudson CM, Korsmeyer SJ, Johnson EM. Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation. Experimental Neurology. 152: 150-62. PMID 9682022 DOI: 10.1006/Exnr.1998.6846 |
0.505 |
|
1998 |
Horger BA, Nishimura MC, Armanini MP, Wang LC, Poulsen KT, Rosenblad C, Kirik D, Moffat B, Simmons L, Johnson E, Milbrandt J, Rosenthal A, Bjorklund A, Vandlen RA, Hynes MA, et al. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4929-37. PMID 9634558 DOI: 10.1523/Jneurosci.18-13-04929.1998 |
0.48 |
|
1998 |
Baloh RH, Gorodinsky A, Golden JP, Tansey MG, Keck CL, Popescu NC, Johnson EM, Milbrandt J. GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. Proceedings of the National Academy of Sciences of the United States of America. 95: 5801-6. PMID 9576965 DOI: 10.1073/Pnas.95.10.5801 |
0.587 |
|
1998 |
Cheng Y, Deshmukh M, D'Costa A, Demaro JA, Gidday JM, Shah A, Sun Y, Jacquin MF, Johnson EM, Holtzman DM. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. The Journal of Clinical Investigation. 101: 1992-9. PMID 9576764 DOI: 10.1172/Jci2169 |
0.519 |
|
1998 |
Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, ... ... Johnson EM, et al. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron. 20: 245-53. PMID 9491986 DOI: 10.1016/S0896-6273(00)80453-5 |
0.671 |
|
1997 |
Easton RM, Deckwerth TL, Parsadanian AS, Johnson EM. Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9656-66. PMID 9391020 DOI: 10.1523/Jneurosci.17-24-09656.1997 |
0.539 |
|
1997 |
Miller TM, Moulder KL, Knudson CM, Creedon DJ, Deshmukh M, Korsmeyer SJ, Johnson EM. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. The Journal of Cell Biology. 139: 205-17. PMID 9314540 DOI: 10.1083/Jcb.139.1.205 |
0.546 |
|
1997 |
Heuckeroth RO, Kotzbauer P, Copeland NG, Gilbert DJ, Jenkins NA, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3. Genomics. 44: 137-40. PMID 9286710 DOI: 10.1006/Geno.1997.4846 |
0.34 |
|
1997 |
Nichol PF, Chang JY, Johnson EM, Olivo PD. Infection of sympathetic and sensory neurones with herpes simplex virus does not elicit a shut-off of cellular protein synthesis: implications for viral latency and herpes vectors. Neurobiology of Disease. 1: 83-94. PMID 9216990 DOI: 10.1006/Nbdi.1994.0011 |
0.385 |
|
1997 |
Creedon DJ, Tansey MG, Baloh RH, Osborne PA, Lampe PA, Fahrner TJ, Heuckeroth RO, Milbrandt J, Johnson EM. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 7018-23. PMID 9192684 DOI: 10.1073/Pnas.94.13.7018 |
0.68 |
|
1997 |
Deshmukh M, Johnson EM. Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Molecular Pharmacology. 51: 897-906. PMID 9187255 DOI: 10.1124/Mol.51.6.897 |
0.663 |
|
1997 |
Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron. 18: 793-802. PMID 9182803 DOI: 10.1016/S0896-6273(00)80318-9 |
0.62 |
|
1997 |
Dugan LL, Creedon DJ, Johnson EM, Holtzman DM. Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway Proceedings of the National Academy of Sciences of the United States of America. 94: 4086-4091. PMID 9108109 DOI: 10.1073/Pnas.94.8.4086 |
0.513 |
|
1997 |
Miller TM, Tansey MG, Johnson EM, Creedon DJ. Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells Journal of Biological Chemistry. 272: 9847-9853. PMID 9092520 DOI: 10.1074/Jbc.272.15.9847 |
0.61 |
|
1996 |
Deshmukh M, Vasilakos J, Deckwerth TL, Lampe PA, Shivers BD, Johnson EM. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. The Journal of Cell Biology. 135: 1341-54. PMID 8947555 DOI: 10.1083/Jcb.135.5.1341 |
0.644 |
|
1996 |
Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM, Milbrandt J. Neurturin, a relative of glial-cell-line-derived neurotrophic factor Nature. 384: 467-470. PMID 8945474 DOI: 10.1038/384467A0 |
0.511 |
|
1996 |
Johnson EM, Deckwerth TL, Deshmukh M. Neuronal death in developmental models: possible implications in neuropathology. Brain Pathology (Zurich, Switzerland). 6: 397-409. PMID 8944313 DOI: 10.1111/J.1750-3639.1996.Tb00872.X |
0.629 |
|
1996 |
Miller TM, Johnson EM. Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells Journal of Neuroscience. 16: 7487-7495. PMID 8922404 DOI: 10.1523/Jneurosci.16-23-07487.1996 |
0.398 |
|
1996 |
Bullock ED, Johnson EM. Nerve growth factor induces the expression of certain cytokine genes and bcl-2 in mast cells: Potential role in survival promotion Journal of Biological Chemistry. 271: 27500-27508. PMID 8910334 DOI: 10.1074/Jbc.271.44.27500 |
0.388 |
|
1996 |
Deckwerth TL, Elliott JL, Knudson CM, Johnson EM, Snider WD, Korsmeyer SJ. BAX is required for neuronal death after trophic factor deprivation and during development. Neuron. 17: 401-11. PMID 8816704 DOI: 10.1016/S0896-6273(00)80173-7 |
0.507 |
|
1996 |
Nichol PF, Chang JY, Johnson EM, Olivo PD. Herpes simplex virus gene expression in neurons: viral DNA synthesis is a critical regulatory event in the branch point between the lytic and latent pathways. Journal of Virology. 70: 5476-86. PMID 8764059 DOI: 10.1128/Jvi.70.8.5476-5486.1996 |
0.362 |
|
1996 |
Creedon DJ, Johnson EM, Lawrence JC. Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival. The Journal of Biological Chemistry. 271: 20713-8. PMID 8702822 DOI: 10.1074/Jbc.271.34.20713 |
0.436 |
|
1996 |
Johnson EM. 571 Metabolic and genetics events Involved in neuronal programmed cell death Neurobiology of Aging. 17: S142. DOI: 10.1016/S0197-4580(96)80573-2 |
0.385 |
|
1995 |
Greenlund LJ, Deckwerth TL, Johnson EM. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 14: 303-15. PMID 7857640 DOI: 10.1016/0896-6273(95)90287-2 |
0.503 |
|
1995 |
Silos-Santiago I, Greenlund LJ, Johnson EM, Snider WD. Molecular genetics of neuronal survival. Current Opinion in Neurobiology. 5: 42-9. PMID 7773004 DOI: 10.1016/0959-4388(95)80085-9 |
0.443 |
|
1995 |
Lampe PA, Cornbrooks EB, Juhasz A, Johnson EM, Franklin JL. Suppression of programmed neuronal death by a thapsigargin-induced Ca2+ influx. Journal of Neurobiology. 26: 205-12. PMID 7707042 DOI: 10.1002/Neu.480260205 |
0.332 |
|
1995 |
Greenlund LJ, Korsmeyer SJ, Johnson EM. Role of BCL-2 in the survival and function of developing and mature sympathetic neurons. Neuron. 15: 649-61. PMID 7546744 DOI: 10.1016/0896-6273(95)90153-1 |
0.535 |
|
1995 |
Franklin J, Sanz-Rodriguez C, Juhasz A, Deckwerth T, Johnson E. Chronic depolarization prevents programmed death of sympathetic neurons in vitro but does not support growth: requirement for Ca2+ influx but not Trk activation The Journal of Neuroscience. 15: 643-664. DOI: 10.1523/Jneurosci.15-01-00643.1995 |
0.356 |
|
1994 |
Kotzbauer PT, Lampe PA, Estus S, Milbrandt J, Johnson EM. Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor Neuron. 12: 763-773. PMID 8161448 DOI: 10.1016/0896-6273(94)90329-8 |
0.516 |
|
1994 |
Freeman RS, Estus S, Johnson EM. Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death. Neuron. 12: 343-55. PMID 8110463 DOI: 10.1016/0896-6273(94)90276-3 |
0.65 |
|
1994 |
Deckwerth TL, Johnson EM. Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis). Developmental Biology. 165: 63-72. PMID 8088451 DOI: 10.1006/Dbio.1994.1234 |
0.5 |
|
1994 |
Laycock KA, Brady RH, Lee SF, Osborne PA, Johnson EM, Pepose JS. The role of nerve growth factor in modulating herpes simplex virus reactivation in vivo Graefe's Archive For Clinical and Experimental Ophthalmology. 232: 421-425. PMID 7926874 DOI: 10.1007/Bf00186584 |
0.364 |
|
1994 |
Franklin JL, Johnson EM. Elevated intracellular calcium blocks programmed neuronal death. Annals of the New York Academy of Sciences. 747: 195-204. PMID 7847671 DOI: 10.1111/J.1749-6632.1994.Tb44410.X |
0.384 |
|
1994 |
Franklin JL, Johnson EM. Block of neuronal apoptosis by a sustained increase of steady-state free Ca2+ concentration. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 251-6. PMID 7846122 DOI: 10.1098/Rstb.1994.0102 |
0.395 |
|
1994 |
Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM. Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. The Journal of Cell Biology. 127: 1717-27. PMID 7798322 DOI: 10.1083/Jcb.127.6.1717 |
0.651 |
|
1994 |
Johnson EM. Possible role of neuronal apoptosis in Alzheimer's disease Neurobiology of Aging. 15: 187-189. PMID 7700450 DOI: 10.1016/0197-4580(94)90202-X |
0.398 |
|
1994 |
Deckwerth TL, Johnson EM. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. The Journal of Cell Biology. 123: 1207-22. PMID 7503996 DOI: 10.1083/Jcb.123.5.1207 |
0.508 |
|
1993 |
Deckwerth TL, Johnson EM. Neurotrophic factor deprivation-induced death. Annals of the New York Academy of Sciences. 679: 121-31. PMID 8512180 DOI: 10.1111/J.1749-6632.1993.Tb18293.X |
0.48 |
|
1993 |
Smith CJ, Johnson EM, Osborne P, Freeman RS, Neveu I, Brachet P. NGF deprivation and neuronal degeneration trigger altered beta-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro. Brain Research. Molecular Brain Research. 17: 328-34. PMID 8510504 DOI: 10.1016/0169-328X(93)90018-K |
0.645 |
|
1993 |
Johnson EM, Deckwerth TL. Molecular mechanisms of developmental neuronal death Annual Review of Neuroscience. 16: 31-46. PMID 8460896 DOI: 10.1146/ANNUREV.NE.16.030193.000335 |
0.315 |
|
1993 |
Freeman RS, Estus S, Horigome K, Johnson EM. Cell death genes in invertebrates and (maybe) vertebrates. Current Opinion in Neurobiology. 3: 25-31. PMID 8453285 DOI: 10.1016/0959-4388(93)90031-S |
0.548 |
|
1993 |
Henderson TA, Rhoades RW, Bennett-Clarke CA, Osborne PA, Johnson EM, Jacquin MF. NGF augmentation rescues trigeminal ganglion and principalis neurons, but not brainstem or cortical whisker patterns, after infraorbital nerve injury at birth Journal of Comparative Neurology. 336: 243-260. PMID 8245217 DOI: 10.1002/Cne.903360207 |
0.412 |
|
1993 |
Martin DP, Ito A, Horigome K, Lampe PA, Johnson EM. Biochemical characterization of programmed cell death in NGF-deprived sympathetic neurons. Journal of Neurobiology. 23: 1205-20. PMID 1335032 DOI: 10.1002/Neu.480230911 |
0.488 |
|
1992 |
Johnson EM, Koike T, Franklin J. A "calcium set-point hypothesis" of neuronal dependence on neurotrophic factor. Experimental Neurology. 115: 163-6. PMID 1728563 DOI: 10.1016/0014-4886(92)90242-I |
0.4 |
|
1992 |
Ferguson IA, Johnson EM. Fibroblast growth factor receptor-bearing neurons in the CNS: identification by receptor-mediated retrograde transport. The Journal of Comparative Neurology. 313: 693-706. PMID 1664437 DOI: 10.1002/Cne.903130412 |
0.499 |
|
1992 |
Smith RL, Pizer LI, Johnson EM, Wilcox CL. Activation of second-messenger pathways reactivates latent herpes simplex virus in neuronal cultures. Virology. 188: 311-8. PMID 1314458 DOI: 10.1016/0042-6822(92)90760-M |
0.449 |
|
1992 |
Franklin JL, Johnson EM. Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends in Neurosciences. 15: 501-8. PMID 1282751 DOI: 10.1016/0166-2236(92)90103-F |
0.409 |
|
1992 |
Smith C, Brachet P, Johnson E. Altered amyloid precursor protein (APP) gene expression during neuronal degeneration Neurobiology of Aging. 13: S85. DOI: 10.1016/0197-4580(92)90464-9 |
0.373 |
|
1991 |
Ferguson IA, Schweitzer JB, Bartlett PF, Johnson EM. Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors. The Journal of Comparative Neurology. 313: 680-92. PMID 1664436 DOI: 10.1002/Cne.903130411 |
0.46 |
|
1991 |
Chang JY, Johnson EM, Olivo PD. A gene delivery/recall system for neurons which utilizes ribonucleotide reductase-negative herpes simplex viruses Virology. 185: 437-440. PMID 1656596 DOI: 10.1016/0042-6822(91)90794-C |
0.375 |
|
1990 |
Yan Q, Johnson EM. Immunohistochemical localization and biochemical characterization of nerve growth factor receptor in adult rat brain. The Journal of Comparative Neurology. 290: 585-98. PMID 2559110 DOI: 10.1002/Cne.902900411 |
0.427 |
|
1990 |
Ruit KG, Osborne PA, Schmidt RE, Johnson EM, Snider WD. Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2412-9. PMID 2376779 DOI: 10.1523/Jneurosci.10-07-02412.1990 |
0.426 |
|
1990 |
Wanaka A, Johnson EM. Developmental study of nerve growth factor receptor mRNA expression in the postnatal rat cerebellum. Brain Research. Developmental Brain Research. 55: 288-92. PMID 2174751 DOI: 10.1016/0165-3806(90)90211-G |
0.313 |
|
1990 |
Wanaka A, Johnson EM, Milbrandt J. Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron. 5: 267-81. PMID 2169267 DOI: 10.1016/0896-6273(90)90164-B |
0.395 |
|
1990 |
Yan Q, Clark HB, Johnson EM. Nerve growth factor receptor in neural lobe of rat pituitary gland: immunohistochemical localization, biochemical characterization and regulation. Journal of Neurocytology. 19: 302-12. PMID 2167948 DOI: 10.1007/Bf01188400 |
0.362 |
|
1990 |
Chang JY, Martin DP, Johnson EM. Interferon suppresses sympathetic neuronal cell death caused by nerve growth factor deprivation. Journal of Neurochemistry. 55: 436-45. PMID 2164567 DOI: 10.1111/J.1471-4159.1990.Tb04155.X |
0.466 |
|
1990 |
Ferguson I, Schweitzer J, Johnson E. Basic fibroblast growth factor: receptor-mediated internalization, metabolism, and anterograde axonal transport in retinal ganglion cells The Journal of Neuroscience. 10: 2176-2189. DOI: 10.1523/Jneurosci.10-07-02176.1990 |
0.34 |
|
1990 |
Martin D, Wallace T, Johnson E. Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction The Journal of Neuroscience. 10: 184-193. DOI: 10.1523/Jneurosci.10-01-00184.1990 |
0.527 |
|
1989 |
Johnson EM, Chang JY, Koike T, Martin DP. Why do neurons die when deprived of trophic factor? Neurobiology of Aging. 10: 549-52; discussion 5. PMID 2812227 DOI: 10.1016/0197-4580(89)90127-9 |
0.466 |
|
1989 |
Koike T, Martin DP, Johnson EM. Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 6421-5. PMID 2548215 DOI: 10.1073/Pnas.86.16.6421 |
0.394 |
|
1989 |
Johnson EM, Osborne PA, Taniuchi M. Destruction of sympathetic and sensory neurons in the developing rat by a monoclonal antibody against the nerve growth factor (NGF) receptor Brain Research. 478: 166-170. PMID 2538200 DOI: 10.1016/0006-8993(89)91491-1 |
0.501 |
|
1989 |
Wallace T, Johnson E. Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis The Journal of Neuroscience. 9: 115-124. DOI: 10.1523/JNEUROSCI.09-01-00115.1989 |
0.324 |
|
1988 |
Laing NG, Osborne PA, Johnson EM. Muscle spindle number is normal in guinea pigs with reduced dorsal root ganglia following in utero deprivation of nerve growth factor Brain Research. 444: 351-355. PMID 2965960 DOI: 10.1016/0006-8993(88)90945-6 |
0.304 |
|
1988 |
Johnson EM. Regulation of nerve growth factor receptor expression on Schwann cells Progress in Brain Research. 78: 327-331. PMID 2854638 DOI: 10.1016/S0079-6123(08)60300-3 |
0.497 |
|
1988 |
DiStefano PS, Johnson EM. Identification of a truncated form of the nerve growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 270-4. PMID 2829174 DOI: 10.1073/Pnas.85.1.270 |
0.666 |
|
1988 |
DiStefano PS, Johnson EM. Nerve growth factor receptors on cultured rat Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 231-41. PMID 2828562 DOI: 10.1523/Jneurosci.08-01-00231.1988 |
0.64 |
|
1988 |
Johnson EM, Taniuchi M. Nerve growth factor (NGF) receptors in the central nervous system. Biochemical Pharmacology. 36: 4189-95. PMID 2825719 DOI: 10.1016/0006-2952(87)90658-7 |
0.37 |
|
1988 |
Yan Q, Snider WD, Pinzone JJ, Johnson EM. Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: assessment of potential neurotrophic effects. Neuron. 1: 335-43. PMID 2483324 DOI: 10.1016/0896-6273(88)90082-7 |
0.373 |
|
1988 |
Johnson EM, Taniuchi M, DiStefano PS. Expression and possible function of nerve growth factor receptors on Schwann cells. Trends in Neurosciences. 11: 299-304. PMID 2465632 DOI: 10.1016/0166-2236(88)90090-2 |
0.674 |
|
1988 |
Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. The Journal of Cell Biology. 106: 829-44. PMID 2450099 DOI: 10.1083/Jcb.106.3.829 |
0.715 |
|
1988 |
Yan Q, Johnson E. An immunohistochemical study of the nerve growth factor receptor in developing rats The Journal of Neuroscience. 8: 3481-3498. DOI: 10.1523/Jneurosci.08-09-03481.1988 |
0.384 |
|
1988 |
Taniuchi M, Clark H, Schweitzer J, Johnson E. Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties The Journal of Neuroscience. 8: 664-681. DOI: 10.1523/Jneurosci.08-02-00664.1988 |
0.409 |
|
1987 |
Palmatier MA, Schmidt RE, Plurad SB, Johnson EM. Sympathetic neuronal destruction in macaque monkeys by guanethidine and guanacline. Annals of Neurology. 21: 46-52. PMID 3827214 DOI: 10.1002/Ana.410210109 |
0.472 |
|
1987 |
Yip HK, Johnson EM. Comparative dynamics of retrograde transport of nerve growth factor and horseradish peroxidase in rat lumbar dorsal root ganglia. Journal of Neurocytology. 15: 789-98. PMID 3819780 DOI: 10.1007/Bf01625195 |
0.461 |
|
1987 |
Rich KM, Luszczynski JR, Osborne PA, Johnson EM. Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury Journal of Neurocytology. 16: 261-268. PMID 3625240 DOI: 10.1007/Bf01795309 |
0.49 |
|
1987 |
Wallace TL, Johnson EM. Partial purification of a parasympathetic neurotrophic factor in pig lung. Brain Research. 411: 351-63. PMID 3607439 DOI: 10.1016/0006-8993(87)91087-0 |
0.394 |
|
1987 |
Yan Q, Johnson EM. A quantitative study of the developmental expression of nerve growth factor (NGF) receptor in rats. Developmental Biology. 121: 139-48. PMID 3032712 DOI: 10.1016/0012-1606(87)90147-3 |
0.365 |
|
1987 |
Yip HK, Johnson EM. Nerve growth factor receptors in rat spinal cord: An autoradiographic and immunohistochemical study Neuroscience. 22: 267-279. PMID 2819775 DOI: 10.1016/0306-4522(87)90217-X |
0.347 |
|
1987 |
Johnson E, Taniuchi M, Clark H, Springer J, Koh S, Tayrien M, Loy R. Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system The Journal of Neuroscience. 7: 923-929. DOI: 10.1523/Jneurosci.07-03-00923.1987 |
0.407 |
|
1986 |
Johnson EM, Palmatier MA, Rydel RE, Manning PT. Species and structural specificity of the lipopigment accumulation and neuronal destruction induced by N-(2-guanidinoethyl)-4-methyl-1,2,5,6-tetrahydropyridine (guanacline). Brain Research. 383: 100-9. PMID 3768685 DOI: 10.1016/0006-8993(86)90011-9 |
0.434 |
|
1986 |
Wallace TL, Johnson EM. Characterization of choline acetyltransferase-sustaining and survival-promoting activities for parasympathetic neurons in pig lung. Brain Research. 375: 92-101. PMID 3719361 DOI: 10.1016/0006-8993(86)90962-5 |
0.396 |
|
1986 |
Sikich L, Woolsey TA, Johnson EM. Effect of a uniform partial denervation of the periphery on the peripheral and central vibrissal system in guinea pigs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1227-40. PMID 3711979 DOI: 10.1523/Jneurosci.06-05-01227.1986 |
0.366 |
|
1986 |
Taniuchi M, Clark HB, Johnson EM. Induction of nerve growth factor receptor in Schwann cells after axotomy. Proceedings of the National Academy of Sciences of the United States of America. 83: 4094-8. PMID 3012551 DOI: 10.1073/Pnas.83.11.4094 |
0.404 |
|
1986 |
Taniuchi M, Schweitzer JB, Johnson EM. Nerve growth factor receptor molecules in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 83: 1950-4. PMID 2419914 DOI: 10.1073/Pnas.83.6.1950 |
0.382 |
|
1986 |
Taniuchi M, Johnson EM, Roach PJ, Lawrence JC. Phosphorylation of nerve growth factor receptor proteins in sympathetic neurons and PC12 cells. In vitro phosphorylation by the cAMP-independent protein kinase FA/GSK-3. Journal of Biological Chemistry. 261: 13342-13349. DOI: 10.1016/s0021-9258(18)69310-x |
0.317 |
|
1986 |
Johnson EM, Rich KM, Yip HK. The role of NGF in sensory neurons in vivo Trends in Neurosciences. 9: 33-37. DOI: 10.1016/0166-2236(86)90012-3 |
0.489 |
|
1985 |
Rich KM, Johnson EM. Ventral rhizotomy enhances regeneration of uninjured sensory neurons Brain Research. 335: 182-187. PMID 4039959 DOI: 10.1016/0006-8993(85)90292-6 |
0.43 |
|
1985 |
Johnson EM, Yip HK. Central nervous system and peripheral nerve growth factor provide trophic support critical to mature sensory neuronal survival. Nature. 314: 751-2. PMID 3990804 DOI: 10.1038/314751A0 |
0.52 |
|
1985 |
McDougal DB, McDougal SH, Johnson EM. Effect of capsaicin upon fluoride sensitive acid phosphatases in selected ganglia and spinal cord and upon neuronal size and number in dorsal root ganglion Brain Research. 331: 63-70. PMID 3986564 DOI: 10.1016/0006-8993(85)90715-2 |
0.431 |
|
1985 |
Manning PT, Russell JH, Simmons B, Johnson EM. Protection from guanethidine-induced neuronal destruction by nerve growth factor: effect of NGF on immune function. Brain Research. 340: 61-9. PMID 3161586 DOI: 10.1016/0006-8993(85)90773-5 |
0.449 |
|
1985 |
DiStefano PS, Schweitzer JB, Taniuchi M, Johnson EM. Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor. The Journal of Cell Biology. 101: 1107-14. PMID 2993314 DOI: 10.1083/Jcb.101.3.1107 |
0.683 |
|
1985 |
Taniuchi M, Johnson EM. Characterization of the binding properties and retrograde axonal transport of a monoclonal antibody directed against the rat nerve growth factor receptor. The Journal of Cell Biology. 101: 1100-6. PMID 2411735 DOI: 10.1083/Jcb.101.3.1100 |
0.358 |
|
1984 |
Rich KM, Yip HK, Osborne PA, Schmidt RE, Johnson EM. Role of nerve growth factor in the adult dorsal root ganglia neuron and its response to injury Journal of Comparative Neurology. 230: 110-118. PMID 6392356 DOI: 10.1002/Cne.902300110 |
0.476 |
|
1984 |
Yip HK, Johnson EM. Developing dorsal root ganglion neurons require trophic support from their central processes: evidence for a role of retrogradely transported nerve growth factor from the central nervous system to the periphery. Proceedings of the National Academy of Sciences of the United States of America. 81: 6245-9. PMID 6207540 DOI: 10.1073/PNAS.81.19.6245 |
0.316 |
|
1984 |
Johnson EM, Manning PT. Guanethidine-induced destruction of sympathetic neurons. International Review of Neurobiology. 25: 1-37. PMID 6206012 DOI: 10.1016/S0074-7742(08)60676-5 |
0.496 |
|
1984 |
Yip H, Rich K, Lampe P, Johnson E. The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia The Journal of Neuroscience. 4: 2986-2992. DOI: 10.1523/Jneurosci.04-12-02986.1984 |
0.521 |
|
1984 |
Palmatier M, Hartman B, Johnson E. Demonstration of retrogradely transported endogenous nerve growth factor in axons of sympathetic neurons The Journal of Neuroscience. 4: 751-756. DOI: 10.1523/Jneurosci.04-03-00751.1984 |
0.393 |
|
1983 |
Johnson EM, Osborne PA, Rydel RE, Schmdt RE, Pearson J. Characterization of the effects of autoimmune nerve growth factor deprivation in the developing guinea-pig Neuroscience. 8: 631-642. PMID 6856089 DOI: 10.1016/0306-4522(83)90204-X |
0.39 |
|
1983 |
Pearson J, Johnson EM, Brandeis L. Effects of antibodies to nerve growth factor on intrauterine development of derivatives of cranial neural crest and placode in the guinea pig Developmental Biology. 96: 32-36. PMID 6825957 DOI: 10.1016/0012-1606(83)90308-1 |
0.335 |
|
1983 |
Schmidt RE, Modert CW, Yip HK, Johnson EM. Retrograde axonal transport of intravenously administered 125I-nerve growth factor in rats with streptozotocin-induced diabetes. Diabetes. 32: 654-63. PMID 6345245 DOI: 10.2337/Diab.32.7.654 |
0.359 |
|
1983 |
Manning P, Powers C, Schmidt R, Johnson E. Guanethidine-induced destruction of peripheral sympathetic neurons occurs by an immune-mediated mechanism The Journal of Neuroscience. 3: 714-724. DOI: 10.1523/Jneurosci.03-04-00714.1983 |
0.425 |
|
1982 |
Bell J, Gruenthal M, Finger S, Lundberg P, Johnson E. Behavioral effects of early deprivation of nerve growth factor: Some similarities with familial dysautonomia Brain Research. 234: 409-421. PMID 7059836 DOI: 10.1016/0006-8993(82)90880-0 |
0.372 |
|
1982 |
Kornblum HI, Johnson EM. Time and dose dependencies of effects of nerve growth factor on sympathetic and sensory neurons in neonatal rats. Brain Research. 234: 41-51. PMID 7059824 DOI: 10.1016/0006-8993(82)90471-1 |
0.41 |
|
1982 |
Schwartz JP, Pearson J, Johnson EM. Effect of exposure to anti-NGF on sensory neurons of adult rats and guinea pigs. Brain Research. 244: 378-81. PMID 6180809 DOI: 10.1016/0006-8993(82)90102-0 |
0.466 |
|
1982 |
Manning PT, Russell JH, Johnson EM. Immunosuppressive agents prevent guanethidine-induced destruction of rat sympathetic neurons. Brain Research. 241: 131-43. PMID 6125238 DOI: 10.1016/0006-8993(82)91236-7 |
0.463 |
|
1982 |
Johnson EM, Gorin PD, Osborne PA, Rydel RE, Pearson J. Effects of autoimmune NGF deprivation in the adult rabbit and offspring Brain Research. 240: 131-140. PMID 6124306 DOI: 10.1016/0006-8993(82)90650-3 |
0.409 |
|
1981 |
McDougal DB, Yu MJ, Gorin PD, Johnson EM. Transported enzymes in sciatic nerve and sensory ganglia of rats exposed to maternal antibodies against nerve growth factor. Journal of Neurochemistry. 36: 1847-52. PMID 6165807 DOI: 10.1111/J.1471-4159.1981.Tb00439.X |
0.347 |
|
1981 |
Gorin PD, Johnson EM. Effects of exposure to nerve growth factor antibodies on the developing nervous system of the rat: an experimental autoimmune approach. Developmental Biology. 80: 313-23. PMID 6108884 DOI: 10.1016/0012-1606(80)90407-8 |
0.418 |
|
1981 |
Ross M, Lofstrandh S, Gorin P, Johnson E, Schwartz J. Use of an experimental autoimmune model to define nerve growth factor dependency of peripheral and central substance P-containing neurons in the rat The Journal of Neuroscience. 1: 1304-1311. DOI: 10.1523/Jneurosci.01-11-01304.1981 |
0.428 |
|
1981 |
Pearson J, Brandeis L, Cuello AC, Johnson E. 120 SELECTIVE DEPLETION OF SUBSTANCE P IN FAMILIAL DYSAUTONOMIA AND NERVE GROWTH FACTOR DEPRIVED ANIMALS Journal of Neuropathology and Experimental Neurology. 40: 339. DOI: 10.1097/00005072-198105000-00127 |
0.309 |
|
1980 |
Johnson EM, Gorin PD, Brandeis LD, Pearson J. Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor. Science (New York, N.Y.). 210: 916-8. PMID 7192014 DOI: 10.1126/Science.7192014 |
0.452 |
|
1980 |
Gorin PD, Johnson EM. Effects of long-term nerve growth factor deprivation on the nervous system of the adult rat: an experimental autoimmune approach. Brain Research. 198: 27-42. PMID 6105903 DOI: 10.1016/0006-8993(80)90341-8 |
0.489 |
|
1980 |
Johnson EM, Blumberg HM, Costrini NV, Bradshaw RA. Reduction by reserpine of the accumulation of retrogradely transported [125I]nerve growth factor in sympathetic neurons. Brain Research. 178: 389-401. PMID 92350 DOI: 10.1016/0006-8993(79)90701-7 |
0.395 |
|
1979 |
Gorin P, Johnson EM. Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons Proceedings of the National Academy of Sciences of the United States of America. 76: 5382-5386. PMID 92024 DOI: 10.1073/Pnas.76.10.5382 |
0.447 |
|
1979 |
Johnson EM, Macia RA, Andres RY, Bradshaw RA. The effects of drug which destroy the sympathetic nervous system on the retrograde transport of nerve growth factor. Brain Research. 171: 461-72. PMID 89888 DOI: 10.1016/0006-8993(79)91050-3 |
0.456 |
|
1979 |
Johnson EM, Hunter FE. Chemical sympathectomy by guanidinium adrenergic neuron blocking agents Federation Proceedings. 38. DOI: 10.1016/0006-2952(79)90468-4 |
0.409 |
|
1978 |
Johnson EM, Andres RY, Bradshaw RA. Characterization of the retrograde transport of nerve growth factor (NGF) using high specific activity [125I] NGF. Brain Research. 150: 319-31. PMID 209849 DOI: 10.1016/0006-8993(78)90283-4 |
0.364 |
|
1978 |
Johnson EM. Destruction of the sympathetic nervous system in neonatal rats and hamsters by vinblastine: prevention by concomitant administration of nerve growth factor Brain Research. 141: 105-118. PMID 75043 DOI: 10.1016/0006-8993(78)90620-0 |
0.463 |
|
1978 |
Johnson EM, Caserta MT, Ross LL. Effect of destruction of the postganglionic sympathetic neurons in neonatal rats on development of choline acetyltransferase and survival of preganglionic cholinergic neurons. Brain Research. 136: 455-64. PMID 21722 DOI: 10.1016/0006-8993(77)90070-1 |
0.364 |
|
1976 |
Douglas JR, Johnson EM, Heist JF, Marshall GR, Needleman P. Is the peripheral sympatho-adrenal nervous system necessary for renal hypertension? The Journal of Pharmacology and Experimental Therapeutics. 196: 35-43. PMID 1246014 |
0.406 |
|
1975 |
Johnson EM, Aloe L. Suppression of the in vitro and in vivo cytotoxic effects of guanethidine in sympathetic neurons by nerve growth factor. Brain Research. 81: 519-32. PMID 4140011 DOI: 10.1016/0006-8993(74)90848-8 |
0.5 |
|
1975 |
Douglas JR, Johnson EM, Marshall GR, Heist J, Hartman BK, Needleman P. Development and maintenance of renal hypertension in normal and guanethidine sympathectomized rats. Circulation Research. 36: 171-8. PMID 1093753 DOI: 10.1161/01.Res.36.6.171 |
0.482 |
|
1974 |
Johnson EM, Marshall GR, Needleman P. Modification of responses to sympathetic nerve stimulation by the renin-angiotensin system in rats. British Journal of Pharmacology. 51: 541-7. PMID 4375530 DOI: 10.1111/J.1476-5381.1974.Tb09672.X |
0.501 |
|
1974 |
Needleman P, Marshall GR, Johnson EM. Determinants and modification of adrenergic and vascular resistance in the kidney. The American Journal of Physiology. 227: 665-9. PMID 4369912 DOI: 10.1152/ajplegacy.1974.227.3.665 |
0.375 |
|
1974 |
Needleman P, Douglas JR, Jakschik B, Stoecklein PB, Johnson EM. Release of renal prostaglandin by catecholamines: relationship to renal endocrine function. The Journal of Pharmacology and Experimental Therapeutics. 188: 453-60. PMID 4359555 |
0.386 |
|
1973 |
Ferrendelli JA, Johnson EM, Chang M, Needleman P. Inhibition of brain adenylate cyclase by ethacrynic acid and dithiobisnitrobenzoic acid. Biochemical Pharmacology. 22: 3133-6. PMID 4761572 DOI: 10.1016/0006-2952(73)90206-2 |
0.448 |
|
1973 |
Johnson EM, Lang S, Needleman P. Dissociation of sympathetic compensation from glyceryl trinitrate tolerance. European Journal of Pharmacology. 21: 189-94. PMID 4633119 DOI: 10.1016/0014-2999(73)90225-2 |
0.492 |
|
1973 |
Needleman P, Johnson EM. Mechanism of tolerance development to organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 184: 709-15. PMID 4631470 |
0.378 |
|
1973 |
Frazier WA, Ohlendorf CE, Boyd LF, Aloe L, Johnson EM, Ferrendelli JA, Bradshaw RA. Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth in embryonic chick sensory ganglia: demonstration of independent pathways of stimulation. Proceedings of the National Academy of Sciences of the United States of America. 70: 2448-52. PMID 4365380 DOI: 10.1073/Pnas.70.8.2448 |
0.374 |
|
1973 |
Needleman P, Kauffman AH, Douglas JR, Johnson EM, Marshall GR. Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs. The American Journal of Physiology. 224: 1415-9. PMID 4351298 DOI: 10.1152/ajplegacy.1973.224.6.1415 |
0.4 |
|
1973 |
Douglas JR, Johnson EM, Marshall GR, Jaffe BM, Needleman P. Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII. Prostaglandins. 3: 67-74. PMID 4348364 DOI: 10.1016/0090-6980(73)90138-X |
0.469 |
|
1973 |
Needleman P, Jakschik B, Johnson EM. Sulfhydryl requirement for relaxation of vascular smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. 187: 324-31. PMID 4201275 |
0.363 |
|
1973 |
Levi-Montalcini R, Aloe L, Johnson E. Interaction between nerve growth factor (NGF) and adrenergic blocking agents in sympathetic neurons Life Sciences. 13: cii-ciii. DOI: 10.1016/0024-3205(73)90317-2 |
0.354 |
|
1972 |
Johnson EM, Harkey AB, Blehm DJ, Needleman P. Clearance and metabolism of organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 182: 56-62. PMID 4625289 |
0.366 |
|
1972 |
Needleman P, Lang S, Johnson EM. Organic nitrates: relationship between biotransformation and rational angina pectoris therapy. The Journal of Pharmacology and Experimental Therapeutics. 181: 489-97. PMID 4624401 |
0.368 |
|
1972 |
Lang S, Johnson EM, Needleman P. Metabolism of and vascular responses to glyceryl trinitrate in the eviscerated rat. Biochemical Pharmacology. 21: 422-4. PMID 4622561 DOI: 10.1016/0006-2952(72)90356-5 |
0.458 |
|
1972 |
Blaustein MP, Johnson EM, Needleman P. Calcium-dependent norepinephrine release from presynaptic nerve endings in vitro. Proceedings of the National Academy of Sciences of the United States of America. 69: 2237-40. PMID 4506092 DOI: 10.1073/Pnas.69.8.2237 |
0.49 |
|
1972 |
Needleman P, Johnson EM, Vine W, Flanigan E, Marshall GR. Pharmacology of antagonists of angiotensin I and II. Circulation Research. 31: 862-7. PMID 4345101 DOI: 10.1161/01.Res.31.6.862 |
0.453 |
|
1971 |
Needleman P, Blehm DJ, Harkey AB, Johnson EM, Lang S. The metabolic pathway in the degradation of glyceryl trinitrate. The Journal of Pharmacology and Experimental Therapeutics. 179: 347-53. PMID 5002725 |
0.39 |
|
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