| Year |
Citation |
Score |
| 2024 |
Mary A, Mancuso R, Heneka MT. Immune Activation in Alzheimer Disease. Annual Review of Immunology. PMID 38424470 DOI: 10.1146/annurev-immunol-101921-035222 |
0.352 |
|
| 2024 |
Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38375983 DOI: 10.1002/alz.13703 |
0.358 |
|
| 2024 |
Talavera Andújar B, Mary A, Venegas C, Cheng T, Zaslavsky L, Bolton EE, Heneka MT, Schymanski EL. Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients? Environmental Science & Technology. PMID 38373301 DOI: 10.1021/acs.est.3c10490 |
0.324 |
|
| 2024 |
Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, ... ... Heneka MT, et al. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Molecular Psychiatry. PMID 38216727 DOI: 10.1038/s41380-023-02387-3 |
0.313 |
|
| 2024 |
Teipel SJ, Dyrba M, Kleineidam L, Brosseron F, Levin F, Bruno D, Buerger K, Cosma N, Schneider LS, Düzel E, Glanz W, Fliessbach K, Janowitz D, Kilimann I, Laske C, ... ... Heneka MT, et al. Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline. Alzheimer's & Dementia (Amsterdam, Netherlands). 16: e12510. PMID 38213951 DOI: 10.1002/dad2.12510 |
0.332 |
|
| 2023 |
Teipel SJ, Dyrba M, Levin F, Altenstein S, Berger M, Beyle A, Brosseron F, Buerger K, Burow L, Dobisch L, Ewers M, Fliessbach K, Frommann I, Glanz W, Goerss D, ... ... Heneka MT, et al. Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach. Journal of Alzheimer's Disease Reports. 7: 1055-1076. PMID 37849637 DOI: 10.3233/ADR-230027 |
0.322 |
|
| 2023 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, Häsler LM, McManus R, Ising C, Röske S, Peters O, Cosma NC, Schneider LS, Wang X, ... ... Heneka MT, et al. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimer's Research & Therapy. 15: 13. PMID 36631909 DOI: 10.1186/s13195-022-01118-0 |
0.361 |
|
| 2022 |
Mercan D, Heneka MT. The Contribution of the Locus Coeruleus-Noradrenaline System Degeneration during the Progression of Alzheimer's Disease. Biology. 11. PMID 36552331 DOI: 10.3390/biology11121822 |
0.374 |
|
| 2022 |
Whitson HE, Colton C, El Khoury J, Gate D, Goate A, Heneka MT, Kaddurah-Daouk R, Klein RS, Shinohara ML, Sisodia S, Spudich SS, Stevens B, Tanzi R, Ting JP, Garden G. Infection and inflammation: New perspectives on Alzheimer's disease. Brain, Behavior, & Immunity - Health. 22: 100462. PMID 36118272 DOI: 10.1016/j.bbih.2022.100462 |
0.325 |
|
| 2022 |
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, ... ... Heneka MT, et al. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathologica. PMID 36066633 DOI: 10.1007/s00401-022-02454-z |
0.331 |
|
| 2022 |
Perea JR, Bolós M, Cuadros R, García E, García-Escudero V, Hernández F, McManus RM, Heneka MT, Avila J. p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function. Molecular Neurobiology. PMID 35006531 DOI: 10.1007/s12035-021-02715-0 |
0.336 |
|
| 2021 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, ... ... Heneka MT, et al. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. PMID 34995486 DOI: 10.1016/j.neuron.2021.12.016 |
0.338 |
|
| 2021 |
Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, ... ... Heneka MT, et al. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. Journal of Alzheimer's Disease : Jad. PMID 34924387 DOI: 10.3233/JAD-215196 |
0.378 |
|
| 2021 |
Ravichandran KA, Heneka MT. Inflammasome activation in neurodegenerative diseases. Essays in Biochemistry. 65: 885-904. PMID 34846519 DOI: 10.1042/EBC20210021 |
0.331 |
|
| 2021 |
Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Brückner M, Händler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. The Embo Journal. 40: e108662. PMID 34825707 DOI: 10.15252/embj.2021108662 |
0.649 |
|
| 2021 |
Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J, Walter J. TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits. Acta Neuropathologica Communications. 9: 168. PMID 34663480 DOI: 10.1186/s40478-021-01263-x |
0.351 |
|
| 2021 |
Rueda-Carrasco J, Martin-Bermejo MJ, Pereyra G, Mateo MI, Borroto A, Brosseron F, Kummer MP, Schwartz S, López-Atalaya JP, Alarcon B, Esteve P, Heneka MT, Bovolenta P. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. Embo Reports. e51696. PMID 34569685 DOI: 10.15252/embr.202051696 |
0.654 |
|
| 2021 |
Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia. PMID 34427354 DOI: 10.1002/glia.24077 |
0.323 |
|
| 2021 |
Bergström S, Remnestål J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, Löwenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellgård B, Brosseron F, ... Heneka MT, et al. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Annals of Clinical and Translational Neurology. 8: 1456-1470. PMID 34129723 DOI: 10.1002/acn3.51402 |
0.373 |
|
| 2020 |
Kumar S, Kapadia A, Theil S, Joshi P, Riffel F, Heneka MT, Walter J. Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer's Disease. Frontiers in Molecular Neuroscience. 13: 619639. PMID 33519377 DOI: 10.3389/fnmol.2020.619639 |
0.308 |
|
| 2020 |
Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, ... ... Heneka MT, et al. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage. Clinical. 28: 102495. PMID 33395986 DOI: 10.1016/j.nicl.2020.102495 |
0.323 |
|
| 2020 |
Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid binding protein 3 and ferritin to neurodegeneration and neuroinflammation. Journal of Neurochemistry. PMID 32894885 DOI: 10.1111/Jnc.15175 |
0.436 |
|
| 2020 |
Finsterwalder S, Vlegels N, Gesierich B, Araque Caballero MÁ, Weaver NA, Franzmeier N, Georgakis MK, Konieczny MJ, Koek HL, Karch CM, Graff-Radford NR, Salloway S, Oh H, Allegri RF, Chhatwal JP, ... ... Heneka MT, et al. Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32808747 DOI: 10.1002/Alz.12150 |
0.375 |
|
| 2020 |
Wolfsgruber S, Kleineidam L, Guski J, Polcher A, Frommann I, Roeske S, Spruth EJ, Franke C, Priller J, Kilimann I, Teipel S, Buerger K, Janowitz D, Laske C, Buchmann M, ... ... Heneka M, et al. Minor neuropsychological deficits in patients with subjective cognitive decline. Neurology. PMID 32636322 DOI: 10.1212/Wnl.0000000000010142 |
0.354 |
|
| 2020 |
Beyer MMS, Lonnemann N, Remus A, Latz E, Heneka MT, Korte M. Enduring changes in neuronal function upon systemic inflammation are NLRP3 inflammasome dependent. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32499379 DOI: 10.1523/Jneurosci.0200-20.2020 |
0.403 |
|
| 2020 |
Heneka MT, Golenbock D, Latz E, Morgan D, Brown R. Immediate and long-term consequences of COVID-19 infections for the development of neurological disease. Alzheimer's Research & Therapy. 12: 69. PMID 32498691 DOI: 10.1186/S13195-020-00640-3 |
0.31 |
|
| 2020 |
Unger MS, Li E, Scharnagl L, Poupardin R, Altendorfer B, Mrowetz H, Hutter-Paier B, Weiger TM, Heneka MT, Attems J, Aigner L. CD8 T-cells infiltrate Alzheimer's disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice. Brain, Behavior, and Immunity. PMID 32479993 DOI: 10.1016/J.Bbi.2020.05.070 |
0.407 |
|
| 2020 |
Schröder N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, et al. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. Journal of Neuroinflammation. 17: 131. PMID 32331524 DOI: 10.1186/S12974-020-01816-2 |
0.451 |
|
| 2020 |
McManus RM, Heneka MT. T cells in Alzheimer's disease: space invaders. The Lancet. Neurology. 19: 285-287. PMID 32199089 DOI: 10.1016/S1474-4422(20)30076-4 |
0.349 |
|
| 2020 |
Friker LL, Scheiblich H, Hochheiser IV, Brinkschulte R, Riedel D, Latz E, Geyer M, Heneka MT. β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia. Cell Reports. 30: 3743-3754.e6. PMID 32187546 DOI: 10.1016/J.Celrep.2020.02.025 |
0.439 |
|
| 2020 |
Kleineidam L, Chouraki V, Próchnicki T, van der Lee SJ, Madrid-Márquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, ... ... Heneka MT, et al. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathologica. PMID 32166339 DOI: 10.1007/S00401-020-02138-6 |
0.431 |
|
| 2020 |
Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nature Reviews. Neurology. PMID 32152461 DOI: 10.1038/S41582-020-0323-9 |
0.406 |
|
| 2020 |
Scheiblich H, Trombly M, Ramirez A, Heneka MT. Neuroimmune Connections in Aging and Neurodegenerative Diseases. Trends in Immunology. PMID 32147113 DOI: 10.1016/J.It.2020.02.002 |
0.343 |
|
| 2020 |
Villacampa N, Heneka MT. Microglia in Alzheimer's disease: Local heroes! The Journal of Experimental Medicine. 217. PMID 32126139 DOI: 10.1084/Jem.20192311 |
0.357 |
|
| 2020 |
Heneka MT. An immune-cell signature marks the brain in Alzheimer's disease. Nature. 577: 322-323. PMID 31937952 DOI: 10.1038/D41586-019-03892-8 |
0.36 |
|
| 2019 |
Lučiūnaitė A, McManus RM, Jankunec M, Rácz I, Dansokho C, Dalgėdienė I, Schwartz S, Brosseron F, Heneka MT. Soluble Aβ Oligomers and Protofibrils Induce NLRP3 Inflammasome Activation in Microglia. Journal of Neurochemistry. e14945. PMID 31872431 DOI: 10.1111/Jnc.14945 |
0.447 |
|
| 2019 |
Riester K, Brawek B, Savitska D, Fröhlich N, Zirdum E, Mojtahedi N, Heneka MT, Garaschuk O. In vivo characterization of functional states of cortical microglia during peripheral inflammation. Brain, Behavior, and Immunity. PMID 31837418 DOI: 10.1016/J.Bbi.2019.12.007 |
0.316 |
|
| 2019 |
Mantile F, Capasso A, Villacampa N, Donnini M, Liguori GL, Constantin G, De Berardinis P, Heneka MT, Prisco A. Vaccination with (1-11)E2 in alum efficiently induces an antibody response to β-amyloid without affecting brain β-amyloid load and microglia activation in 3xTg mice. Aging Clinical and Experimental Research. PMID 31758499 DOI: 10.1007/S40520-019-01414-0 |
0.419 |
|
| 2019 |
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, ... ... Heneka MT, et al. NLRP3 inflammasome activation drives tau pathology. Nature. PMID 31748742 DOI: 10.1038/S41586-019-1769-Z |
0.463 |
|
| 2019 |
Venegas C, Heneka MT. Inflammasome-mediated innate immunity in Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900439. PMID 31702392 DOI: 10.1096/Fj.201900439 |
0.453 |
|
| 2019 |
Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunology and Cell Biology. PMID 31654430 DOI: 10.1111/Imcb.12301 |
0.51 |
|
| 2019 |
Brosseron F, Kolbe CC, Santarelli F, Carvalho S, Antonell A, Castro-Gomez S, Tacik P, Namasivayam AA, Mangone G, Schneider R, Latz E, Wüllner U, Svenningsson P, Sánchez-Valle R, Molinuevo JL, ... ... Heneka MT, et al. Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31630996 DOI: 10.1016/J.Jalz.2019.07.018 |
0.39 |
|
| 2019 |
Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Fließbach K, Haynes JD, Heneka MT, Kilimann I, et al. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. Journal of Alzheimer's Disease : Jad. PMID 31594223 DOI: 10.3233/Jad-190446 |
0.4 |
|
| 2019 |
Berron D, Cardenas-Blanco A, Bittner D, Metzger CD, Spottke A, Heneka MT, Fließbach K, Schneider A, Teipel SJ, Wagner M, Speck O, Jessen F, Düzel E. Higher CSF tau levels are related to hippocampal hyperactivity and object mnemonic discrimination in older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31541019 DOI: 10.1523/Jneurosci.1279-19.2019 |
0.337 |
|
| 2019 |
Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. Journal of Neurochemistry. PMID 31520481 DOI: 10.1111/Jnc.14870 |
0.449 |
|
| 2019 |
Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frölich L, Hüll M, Wiltfang J, Scherer M, Riedel-Heller S, ... ... Heneka MT, et al. A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Human Mutation. PMID 31464095 DOI: 10.1002/Humu.23904 |
0.376 |
|
| 2019 |
Bertens D, Vos S, Kehoe P, Wolf H, Nobili F, Mendonça A, van Rossum I, Hort J, Molinuevo JL, Heneka M, Petersen R, Scheltens P, Visser PJ. Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey. Alzheimer's Research & Therapy. 11: 74. PMID 31439020 DOI: 10.1186/S13195-019-0525-9 |
0.388 |
|
| 2019 |
Castro-Gomez S, Binder J, Heneka MT. [Neuroinflammation as motor of Alzheimer's disease]. Der Nervenarzt. PMID 31428829 DOI: 10.1007/S00115-019-0778-3 |
0.404 |
|
| 2019 |
Tejera D, Heneka MT. In Vivo Phagocytosis Analysis of Amyloid Beta. Methods in Molecular Biology (Clifton, N.J.). 2034: 287-292. PMID 31392693 DOI: 10.1007/978-1-4939-9658-2_21 |
0.465 |
|
| 2019 |
Tejera D, Heneka MT. Microglia in Neurodegenerative Disorders. Methods in Molecular Biology (Clifton, N.J.). 2034: 57-67. PMID 31392677 DOI: 10.1007/978-1-4939-9658-2_5 |
0.34 |
|
| 2019 |
Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, ... ... Heneka MT, et al. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimer's Research & Therapy. 11: 66. PMID 31366409 DOI: 10.1186/S13195-019-0515-Y |
0.389 |
|
| 2019 |
Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome. The Embo Journal. e101064. PMID 31359456 DOI: 10.15252/Embj.2018101064 |
0.493 |
|
| 2019 |
Esteve P, Rueda-Carrasco J, Inés Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandonís Á, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, Rábano A, Fortea J, Alcolea D, ... ... Heneka MT, et al. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nature Neuroscience. PMID 31308530 DOI: 10.1038/S41593-019-0432-1 |
0.456 |
|
| 2019 |
Nitsch L, Zimmermann J, Krauthausen M, Hofer MJ, Saggu R, Petzold GC, Heneka MT, Getts DR, Becker A, Campbell IL, Müller M. CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model. Molecular Neurobiology. PMID 31154574 DOI: 10.1007/S12035-019-1640-0 |
0.302 |
|
| 2019 |
Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Heneka MT, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6 |
0.407 |
|
| 2019 |
Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression. Molecular Neurobiology. PMID 30852796 DOI: 10.1007/S12035-019-1540-3 |
0.733 |
|
| 2019 |
Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, ... ... Heneka MT, et al. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimer's Research & Therapy. 11: 8. PMID 30654834 DOI: 10.1186/S13195-018-0463-Y |
0.395 |
|
| 2019 |
Heneka MT. Microglia take centre stage in neurodegenerative disease. Nature Reviews. Immunology. PMID 30610221 DOI: 10.1038/S41577-018-0112-5 |
0.303 |
|
| 2019 |
Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-339: Cortical Thickness And Alzheimer'S Related Biomarkers In Subjective Cognitive Decline - Data From The Delcode-Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.894 |
0.32 |
|
| 2019 |
Sannemann L, Spottke A, Brosseron F, Buerger K, Fließbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, Düzel E, et al. P4-236: The Association Of Ad Pathology With Neuropsychiatric Symptoms And Worry In Subjective Cognitive Decline - Data From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3899 |
0.324 |
|
| 2019 |
Marzban EN, Teipel SJ, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Spottke A, Wagner M, Wiltfang J, Düzel E, Jessen F, et al. P3-361: Explainable Convolutional Networks And Multimodal Imaging Data: The Next Step Towards Using Artificial Intelligence As Diagnostic Tool For Early Detection Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3394 |
0.315 |
|
| 2019 |
Metzger CD, Dyrba M, Bittner D, Hu X, Teipel SJ, Grothe MJ, Peters O, Menne F, Fuentes M, Priller J, Spruth E, Franke C, Schneider A, Fliessbach K, Kofler B, ... ... Heneka MT, et al. P1-407: Relationship Between Global Connectivity, Amyloid And Tau In Different Stages During The Development Of Alzheimer'S Disease As Demonstrated In The Dzne Delcode Cohort Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1012 |
0.405 |
|
| 2019 |
Polcher A, Wolfsgruber S, Spottke A, Peters O, Priller J, Bürger K, Perneczky R, Laske C, Schneider A, Heneka MT, Teipel SJ, Wiltfang J, Düzel E, Jessen F, Wagner M. Subjective Cognitive Decline Versus Subtle Deficits As Indicators Of Preclinical Ad: Results From The Multicenter Observational Study On Predementia Alzheimer’S Disease (Delcode) Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.034 |
0.378 |
|
| 2018 |
Düzel E, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Betts M, Ziegler G, Chen Y, Dobisch L, Bittner D, Glanz W, Reuter M, Spottke A, Rudolph J, Brosseron F, ... ... Heneka M, et al. CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 782-790. PMID 30555890 DOI: 10.1016/J.Dadm.2018.10.003 |
0.371 |
|
| 2018 |
Hu X, Teunissen C, Spottke A, Heneka MT, Düzel E, Peters O, Li S, Priller J, Bürger K, Teipel S, Laske C, Verfaillie S, Barkhof F, Coll-Padrós N, Rami L, et al. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321506 DOI: 10.1016/J.Jalz.2018.09.002 |
0.408 |
|
| 2018 |
Ativie F, Komorowska JA, Beins E, Albayram Ö, Zimmer T, Zimmer A, Tejera D, Heneka M, Bilkei-Gorzo A. Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity. Frontiers in Molecular Neuroscience. 11: 295. PMID 30210289 DOI: 10.3389/Fnmol.2018.00295 |
0.382 |
|
| 2018 |
Heneka MT, McManus RM, Latz E. Inflammasome signalling in brain function and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 30206330 DOI: 10.1038/S41583-018-0055-7 |
0.396 |
|
| 2018 |
Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127003 DOI: 10.1073/Pnas.1801802115 |
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| 2018 |
Faivre E, Coelho JE, Zornbach K, Malik E, Baqi Y, Schneider M, Cellai L, Carvalho K, Sebda S, Figeac M, Eddarkaoui S, Caillierez R, Chern Y, Heneka M, Sergeant N, et al. Beneficial Effect of a Selective Adenosine A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 235. PMID 30050407 DOI: 10.3389/Fnmol.2018.00235 |
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| 2018 |
Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J, Parsons CG. The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP). Neuropharmacology. PMID 30016667 DOI: 10.1016/J.Neuropharm.2018.07.021 |
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| 2018 |
Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, ... ... Heneka MT, et al. Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial. The Lancet. Neurology. PMID 29934198 DOI: 10.1016/S1474-4422(18)30176-5 |
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| 2018 |
Teipel SJ, Metzger C, Brosseron F, Buerger K, Brueggen K, Catak C, Diesing D, Dobisch L, Fliebach K, Franke C, Heneka M, Kilimann I, Kofler B, Menne F, Peters O, et al. Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29914027 DOI: 10.3233/Jad-180106 |
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| 2018 |
Kalinin S, González-Prieto M, Scheiblich H, Lisi L, Kusumo H, Heneka MT, Madrigal JLM, Pandey SC, Feinstein DL. Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. Journal of Neuroinflammation. 15: 141. PMID 29759078 DOI: 10.1186/S12974-018-1184-7 |
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| 2018 |
Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Roßner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29630865 DOI: 10.1016/J.Jalz.2018.02.017 |
0.352 |
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| 2018 |
Enkirch SJ, Traschütz A, Müller A, Widmann CN, Gielen GH, Heneka MT, Jurcoane A, Schild HH, Hattingen E. The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease. Radiology. 171888. PMID 29514015 DOI: 10.1148/Radiol.2018171888 |
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| 2018 |
Brosseron F, Traschütz A, Widmann CN, Kummer MP, Tacik P, Santarelli F, Jessen F, Heneka MT. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimer's Research & Therapy. 10: 25. PMID 29482610 DOI: 10.1186/S13195-018-0353-3 |
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| 2018 |
Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Heneka MT, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008 |
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| 2018 |
Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, et al. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimer's Research & Therapy. 10: 15. PMID 29415768 DOI: 10.1186/S13195-017-0314-2 |
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| 2018 |
Ising C, Heneka MT. Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration. Cell Death & Disease. 9: 120. PMID 29371603 DOI: 10.1038/S41419-017-0153-X |
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| 2018 |
Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-379: Cortical Thinning In Subjective Cognitive Decline With And Without Ad Pathology: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.387 |
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| 2018 |
Schipke CG, Menne F, Teipel SJ, Buerger K, Schneider A, Priller J, Christoph L, Wiltfang J, Spottke A, Heneka M, Brosseron F, Wagner M, Düzel E, Jessen F, Peters O. P4-068: Levels Of The Astrocyte-Derived Proteins Gfap And S100B In The Cerebrospinal Fluid Of Healthy Individuals And Alzheimer'S Disease Patients At Different Disease Stages Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2471 |
0.374 |
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| 2018 |
Dyrba M, Metzger CD, Grothe MJ, Spottke A, Buerger K, Schneider A, Peters O, Priller J, Heneka M, Brosseron F, Wagner M, Jessen F, Düzel E, Teipel SJ. P3-366: Multicenter Resting State Functional Connectivity In Prodromal And Dementia Stages Of Alzheimer'S Disease: Results From The Dzne Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1728 |
0.362 |
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| 2018 |
Sannemann L, Hu X, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka M, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, et al. P3-327: Neuropsychiatric Symptoms In At-Risk Groups For Ad Dementia And Their Relation To Ad Biomarkers: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1688 |
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| 2017 |
Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, ... ... Heneka MT, et al. Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease. Nature. 552: 355-361. PMID 29293211 DOI: 10.1038/Nature25158 |
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| 2017 |
Dansokho C, Heneka MT. Neuroinflammatory responses in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 125: 771-779. PMID 29273951 DOI: 10.1007/S00702-017-1831-7 |
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| 2017 |
Tejera D, Heneka MT. United Again: STING and the Police. Neuron. 96: 1207-1208. PMID 29268089 DOI: 10.1016/J.Neuron.2017.12.015 |
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| 2017 |
Kaczmarczyk R, Tejera D, Simon BJ, Heneka MT. Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease. Journal of Neurochemistry. PMID 29266221 DOI: 10.1111/Jnc.14284 |
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| 2017 |
Ardura-Fabregat A, Boddeke EWGM, Boza-Serrano A, Brioschi S, Castro-Gomez S, Ceyzériat K, Dansokho C, Dierkes T, Gelders G, Heneka MT, Hoeijmakers L, Hoffmann A, Iaccarino L, Jahnert S, Kuhbandner K, et al. Targeting Neuroinflammation to Treat Alzheimer's Disease. Cns Drugs. PMID 29260466 DOI: 10.1007/S40263-017-0483-3 |
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| 2017 |
Traschütz A, Kummer MP, Schwartz S, Heneka MT. Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice. Behavioural Processes. PMID 29155004 DOI: 10.1016/J.Beproc.2017.11.009 |
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| 2017 |
Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annual Review of Medicine. PMID 29106805 DOI: 10.1146/Annurev-Med-050715-104343 |
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| 2017 |
Scheiblich H, Schlütter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Activation of the NLRP3 inflammasome in microglia: The role of ceramide. Journal of Neurochemistry. PMID 28940479 DOI: 10.1111/Jnc.14225 |
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| 2017 |
Sarlus H, Heneka MT. Microglia in Alzheimer's disease. The Journal of Clinical Investigation. 127: 3240-3249. PMID 28862638 DOI: 10.1172/Jci90606 |
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| 2017 |
Müller S, Preische O, Göpfert JC, Yañez VAC, Joos TO, Boecker H, Düzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, et al. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Scientific Reports. 7: 9529. PMID 28842559 DOI: 10.1038/S41598-017-08779-0 |
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| 2017 |
Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Kummer MP, Brosseron F, Gieselmann V, Heneka MT. Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags. Journal of Neuroscience Methods. PMID 28789995 DOI: 10.1016/J.Jneumeth.2017.08.005 |
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| 2017 |
Simchovitz A, Heneka MT, Soreq H. Personalized genetics of the cholinergic blockade of neuroinflammation. Journal of Neurochemistry. PMID 28326544 DOI: 10.1111/Jnc.13928 |
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| 2017 |
McManus RM, Heneka MT. Role of neuroinflammation in neurodegeneration: new insights. Alzheimer's Research & Therapy. 9: 14. PMID 28259169 DOI: 10.1186/S13195-017-0241-2 |
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| 2017 |
Zimmermann J, Emrich M, Krauthausen M, Saxe S, Nitsch L, Heneka MT, Campbell IL, Müller M. IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination. Molecular Neurobiology. PMID 28084589 DOI: 10.1007/S12035-016-0368-3 |
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| 2017 |
Venegas C, Heneka MT. Danger-associated molecular patterns in Alzheimer's disease. Journal of Leukocyte Biology. 101: 87-98. PMID 28049142 DOI: 10.1189/Jlb.3Mr0416-204R |
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| 2017 |
Franzmeier N, Wolfsgruber S, Ramirez A, Wagner M, Buerger K, Dichgans M, Heneka M, Falkai P, Teipel SJ, Wiltfang J, Priller J, Laske C, Schneider A, Spottke A, Duzel E, et al. [IC-P-030]: CONNECTIVITY OF THE LEFT FRONTAL CORTEX ATTENUATES DETRIMENTAL EFFECTS OF CSF-TAU ON MEMORY IN PRECLINICAL AND CLINICAL ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P28-P28. DOI: 10.1016/J.Jalz.2017.06.2302 |
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| 2017 |
Unger MS, Marschallinger J, Klein B, Johnson M, Khundakar AA, Heneka M, Couillard-Despres S, Masliah E, Attems J, Aigner L. Immune Cell Interactions In Amyloid-Beta Plaque Pathology Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1341 |
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| 2016 |
Heneka MT. Inflammasome activation and innate immunity in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). PMID 28019679 DOI: 10.1111/Bpa.12483 |
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| 2016 |
Unger MS, Marschallinger J, Kaindl J, Höfling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease. Molecular Neurobiology. PMID 27544234 DOI: 10.1007/S12035-016-0018-9 |
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| 2016 |
Heneka MT, Nicotera P. Thoughts on Obesity and Brain Glucose. Cell. 165: 773-5. PMID 27153489 DOI: 10.1016/J.Cell.2016.04.057 |
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| 2016 |
Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, ... ... Heneka MT, et al. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. Embo Molecular Medicine. PMID 26941262 DOI: 10.15252/Emmm.201506123 |
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| 2015 |
Tejera D, Heneka MT. Microglia in Alzheimer's disease: the good, the bad and the ugly. Current Alzheimer Research. PMID 26567746 DOI: 10.2174/1567205013666151116125012 |
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| 2015 |
Traschütz A, Tzaridis T, Penner AH, Kuchelmeister K, Urbach H, Hattingen E, Heneka MT. Reduction of microbleeds by immunosuppression in a patient with Aβ-related vascular inflammation. Neurology® Neuroimmunology & Neuroinflammation. 2: e165. PMID 26516630 DOI: 10.1212/Nxi.0000000000000165 |
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| 2015 |
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, ... ... Heneka MT, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. PMID 26322584 DOI: 10.1038/Nature14864 |
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| 2015 |
Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S. Effects of macrophage-dependent peroxisome proliferator-activated receptor γ signalling on adhesion formation after abdominal surgery in an experimental model. The British Journal of Surgery. PMID 26313905 DOI: 10.1002/bjs.9907 |
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| 2015 |
Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, et al. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. Plos One. 10: e0132227. PMID 26168044 DOI: 10.1371/Journal.Pone.0132227 |
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| 2015 |
Heneka MT, Fink A, Doblhammer G. Effect of pioglitazone medication on the incidence of dementia. Annals of Neurology. 78: 284-94. PMID 25974006 DOI: 10.1002/Ana.24439 |
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| 2015 |
Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, ... ... Heneka MT, et al. PLD3 in non-familial Alzheimer's disease. Nature. 520: E3-5. PMID 25832411 DOI: 10.1038/Nature14039 |
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| 2015 |
Schmidt R, Hofer E, Bouwman FH, Buerger K, Cordonnier C, Fladby T, Galimberti D, Georges J, Heneka MT, Hort J, Laczó J, Molinuevo JL, O'Brien JT, Religa D, Scheltens P, et al. EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 889-98. PMID 25808982 DOI: 10.1111/Ene.12707 |
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| 2015 |
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5 |
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| 2015 |
Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nature Immunology. 16: 229-36. PMID 25689443 DOI: 10.1038/Ni.3102 |
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| 2015 |
Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, Müller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. The Journal of Clinical Investigation. 125: 365-78. PMID 25500888 DOI: 10.1172/Jci66771 |
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| 2015 |
Meiberth D, Scheef L, Wolfsgruber S, Boecker H, Block W, Träber F, Erk S, Heneka MT, Jacobi H, Spottke A, Walter H, Wagner M, Hu X, Jessen F. Cortical thinning in individuals with subjective memory impairment. Journal of Alzheimer's Disease : Jad. 45: 139-46. PMID 25471190 DOI: 10.3233/Jad-142322 |
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| 2015 |
Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Molecular Neurobiology. 51: 661-71. PMID 24838579 DOI: 10.1007/S12035-014-8743-4 |
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| 2015 |
Herrera-Rivero M, Heneka MT, Papadopoulos V. Translocator protein and new targets for neuroinflammation Clinical and Translational Imaging. 3: 391-402. DOI: 10.1007/S40336-015-0151-X |
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| 2015 |
Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S. Effects of macrophage-dependent peroxisome proliferator-activated receptor γ signalling on adhesion formation after abdominal surgery in an experimental model British Journal of Surgery. DOI: 10.1002/bjs.9907 |
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| 2014 |
Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, ... ... Heneka MT, et al. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiology of Aging. 35: 2657.e13-9. PMID 25042114 DOI: 10.1016/J.Neurobiolaging.2014.06.018 |
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| 2014 |
Kummer MP, Heneka MT. Truncated and modified amyloid-beta species. Alzheimer's Research & Therapy. 6: 28. PMID 25031638 DOI: 10.1186/Alzrt258 |
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| 2014 |
Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, ... ... Heneka MT, et al. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Human Molecular Genetics. 23: 6644-58. PMID 25027320 DOI: 10.1093/Hmg/Ddu372 |
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| 2014 |
Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, ... ... Heneka MT, et al. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 6: 243ra86. PMID 24990881 DOI: 10.1126/Scitranslmed.3009093 |
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| 2014 |
Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8845-54. PMID 24966384 DOI: 10.1523/Jneurosci.4027-13.2014 |
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| 2014 |
Heneka MT, Kummer MP, Latz E. Innate immune activation in neurodegenerative disease. Nature Reviews. Immunology. 14: 463-77. PMID 24962261 DOI: 10.1038/Nri3705 |
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| 2014 |
Krauthausen M, Saxe S, Zimmermann J, Emrich M, Heneka MT, Müller M. CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system. Journal of Neuroinflammation. 11: 109. PMID 24930935 DOI: 10.1186/1742-2094-11-109 |
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| 2014 |
Widmann CN, Heneka MT. Long-term cerebral consequences of sepsis. The Lancet. Neurology. 13: 630-6. PMID 24849863 DOI: 10.1016/S1474-4422(14)70017-1 |
0.367 |
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| 2014 |
Brosseron F, Krauthausen M, Kummer M, Heneka MT. Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview. Molecular Neurobiology. 50: 534-44. PMID 24567119 DOI: 10.1007/S12035-014-8657-1 |
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| 2014 |
Peter J, Scheef L, Abdulkadir A, Boecker H, Heneka M, Wagner M, Koppara A, Klöppel S, Jessen F. Gray matter atrophy pattern in elderly with subjective memory impairment Alzheimer's and Dementia. 10: 99-108. PMID 23867795 DOI: 10.1016/J.Jalz.2013.05.1764 |
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| 2014 |
Malhotra A, Younesi E, Gündel M, Müller B, Heneka MT, Hofmann-Apitius M. ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 238-46. PMID 23830913 DOI: 10.1016/J.Jalz.2013.02.009 |
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| 2014 |
Zimmermann J, Emrich M, Krauthausen M, Saxe S, Heneka M, Campbell I, Müller M. IL-17A promotes myelin loss and inflammatory response during Cuprizone-induced demyelination Journal of Neuroimmunology. 275: 110. DOI: 10.1016/J.Jneuroim.2014.08.296 |
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| 2014 |
Brosseron F, Kummer MP, Krauthausen M, Jessen F, Heneka M. Correlation Of Cerebrospinal Fluid Cytokines With Clinical Markers Of Dementia In Mild Cognitive Impairment And Alzheimer'S Disease Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.786 |
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| 2014 |
Wijasa TS, Brosseron F, Kummer MP, Heneka M. Nitro-Proteomics To Discover Synaptosomal Biomarkers Of Neuroinflammation In Alzheimer'S Disease Alzheimers & Dementia. 10: 360. DOI: 10.1016/J.Jalz.2014.05.402 |
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| 2014 |
Ramirez A, Heilmann S, Drichel D, Hernandez I, Lleó A, Lacour A, Rosende-Roca M, Mauleon A, Ruiz S, Alegret M, Espinosa A, Sotolongo O, Blesa R, Fortea J, Kornhuber J, ... ... Heneka M, et al. Role Of Pld3 Rare Variants In European Sporadic Alzheimer'S Disease Patients Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.281 |
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| 2014 |
Heneka MT. S4-02-01: INNATE IMMUNITY AND REGULATION OF ABETA Alzheimer's & Dementia. 10: P239-P240. DOI: 10.1016/J.Jalz.2014.04.358 |
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| 2014 |
Heneka MT. Alzheimer-Demenz: Praxis und neue Entwicklungen Info Neurologie & Psychiatrie. 16: 40-51. DOI: 10.1007/s15005-014-0002-8 |
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| 2013 |
Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Research & Therapy. 5: 21. PMID 23634965 DOI: 10.1186/Alzrt175 |
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| 2013 |
Molinuevo JL, Gispert JD, Dubois B, Heneka MT, Lleo A, Engelborghs S, Pujol J, de Souza LC, Alcolea D, Jessen F, Sarazin M, Lamari F, Balasa M, Antonell A, Rami L. The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study. Journal of Alzheimer's Disease : Jad. 36: 67-77. PMID 23524657 DOI: 10.3233/Jad-130203 |
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| 2013 |
Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 493: 674-8. PMID 23254930 DOI: 10.1038/Nature11729 |
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| 2013 |
van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, Bäumer V, Maes G, Corsmit E, Borroni B, Padovani A, ... ... Heneka MT, ... ... Heneka MT, ... ... Heneka MT, et al. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Human Mutation. 34: 363-73. PMID 23111906 DOI: 10.1002/Humu.22244 |
0.312 |
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| 2013 |
Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biological Psychiatry. 73: 454-63. PMID 22883210 DOI: 10.1016/J.Biopsych.2012.06.013 |
0.716 |
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| 2013 |
Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiology of Aging. 34: 351-4. PMID 22651996 DOI: 10.1016/J.Neurobiolaging.2012.04.016 |
0.711 |
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| 2013 |
Delgado-Morales R, Patchev A, Llobet-Navas D, Kummer M, Heneka M, Silva J, Almeida O. Delay of Alzheimer's-like pathology in mice with 7,8-dihydroxyflavone Alzheimers & Dementia. 9: 815. DOI: 10.1016/J.Jalz.2013.05.1747 |
0.799 |
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| 2012 |
Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17824-9. PMID 23223301 DOI: 10.1523/Jneurosci.1504-12.2012 |
0.746 |
|
| 2012 |
Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17321-31. PMID 23197723 DOI: 10.1523/Jneurosci.1569-12.2012 |
0.744 |
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| 2012 |
Scheef L, Spottke A, Daerr M, Joe A, Striepens N, Kölsch H, Popp J, Daamen M, Gorris D, Heneka MT, Boecker H, Biersack HJ, Maier W, Schild HH, Wagner M, et al. Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment. Neurology. 79: 1332-9. PMID 22914828 DOI: 10.1212/Wnl.0B013E31826C1A8D |
0.305 |
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| 2012 |
Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A. Glial cells in (patho)physiology. Journal of Neurochemistry. 121: 4-27. PMID 22251135 DOI: 10.1111/J.1471-4159.2012.07664.X |
0.347 |
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| 2012 |
Kummer MP, Hülsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 165-72. PMID 22227962 DOI: 10.1007/S11481-011-9339-7 |
0.684 |
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| 2012 |
Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, Rübe CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1098-107. PMID 22198949 DOI: 10.4049/Jimmunol.1101121 |
0.417 |
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| 2012 |
Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiology of Aging. 33: 426.e1-11. PMID 21109328 DOI: 10.1016/J.Neurobiolaging.2010.10.009 |
0.671 |
|
| 2012 |
Ramirez A, Herold C, Lewczuk P, Lacour A, Drichel D, Schürmann B, Kornhuber J, Peters O, Heun R, Hampel H, Frölich L, Hüll M, Hoffmann P, Vogt S, Kölsch H, ... Heneka M, et al. Genome-wide association study using cerebrospinal fluid biomarkers beta-amyloid-42 and pTau181 in German samples of Alzheimer's disease Alzheimers & Dementia. 8: 663. DOI: 10.1016/J.Jalz.2012.05.1786 |
0.371 |
|
| 2011 |
Heneka MT, Reyes-Irisarri E, Hüll M, Kummer MP. Impact and Therapeutic Potential of PPARs in Alzheimer's Disease. Current Neuropharmacology. 9: 643-50. PMID 22654722 DOI: 10.2174/157015911798376325 |
0.749 |
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| 2011 |
Krauthausen M, Ellis SL, Zimmermann J, Sarris M, Wakefield D, Heneka MT, Campbell IL, Müller M. Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12. The American Journal of Pathology. 179: 2346-59. PMID 21925471 DOI: 10.1016/J.Ajpath.2011.07.041 |
0.311 |
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| 2011 |
Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, König S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation. Neuron. 71: 833-44. PMID 21903077 DOI: 10.1016/J.Neuron.2011.07.001 |
0.744 |
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| 2011 |
Mildner A, Schlevogt B, Kierdorf K, Böttcher C, Erny D, Kummer MP, Quinn M, Brück W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11159-71. PMID 21813677 DOI: 10.1523/Jneurosci.6209-10.2011 |
0.74 |
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| 2011 |
Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, ... ... Heneka MT, et al. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 386-395.e6. PMID 21784349 DOI: 10.1016/J.Jalz.2011.05.2243 |
0.671 |
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| 2011 |
Juckel G, Manitz MP, Brüne M, Friebe A, Heneka MT, Wolf RJ. Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study. Schizophrenia Research. 131: 96-100. PMID 21752601 DOI: 10.1016/J.Schres.2011.06.018 |
0.341 |
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| 2011 |
Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson JÅ, Holtzman DM, Heneka MT. Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7049-59. PMID 21562267 DOI: 10.1523/Jneurosci.6546-10.2011 |
0.732 |
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| 2011 |
Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. The Embo Journal. 30: 2255-65. PMID 21527912 DOI: 10.1038/Emboj.2011.138 |
0.447 |
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| 2011 |
Terwel D, Löschmann YN, Schmidt HH, Schöler HR, Cantz T, Heneka MT. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease. Journal of Neurochemistry. 118: 105-12. PMID 21517843 DOI: 10.1111/J.1471-4159.2011.07278.X |
0.401 |
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| 2011 |
Heneka MT, Kummer MP, Weggen S, Bulic B, Multhaup G, Münter L, Hüll M, Pflanzner T, Pietrzik CU. Molecular mechanisms and therapeutic application of NSAIDs and derived compounds in Alzheimer's disease. Current Alzheimer Research. 8: 115-31. PMID 21345168 DOI: 10.2174/156720511795256099 |
0.724 |
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| 2011 |
Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Thiele A, Heneka MT. Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice. Neuroscience. 176: 396-407. PMID 21129451 DOI: 10.1016/J.Neuroscience.2010.11.052 |
0.722 |
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| 2011 |
Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice. Journal of Neurochemistry. 116: 43-52. PMID 21044080 DOI: 10.1111/J.1471-4159.2010.07083.X |
0.706 |
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| 2011 |
Rapic S, Backes H, Viel T, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka M, Jacobs A. Multi-tracer microPET imaging of a mouse model of Alzheimer's disease to assess microglial activation and anti-inflammatory treatment Klinische Neurophysiologie. 42. DOI: 10.1055/S-0031-1272776 |
0.402 |
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| 2011 |
Kumar S, Rezaei-Ghaleh N, Zweckstetter M, Terwel D, Thal D, Heneka M, Walter J. Site-Specific Effect of Amyloid B-Peptide (Aβ) Phosphorylation on Its Conformation and Aggregation Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2440 |
0.308 |
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| 2011 |
Yamanaka M, Kurzwelly D, Reyes E, Heneka M. PPAR gamma/RXR induced and CD36-mediated Abeta phagocytosis results in cognitive improvement in APP/PS1 mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1158 |
0.349 |
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| 2010 |
Fleisher-Berkovich S, Filipovich-Rimon T, Ben-Shmuel S, Hülsmann C, Kummer MP, Heneka MT. Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides (i). Journal of Neuroinflammation. 7: 61. PMID 20937084 DOI: 10.1186/1742-2094-7-61 |
0.695 |
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| 2010 |
Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, Lütjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. The Journal of Biological Chemistry. 285: 37405-14. PMID 20876579 DOI: 10.1074/Jbc.M110.149468 |
0.369 |
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| 2010 |
Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 919-47. PMID 20632195 DOI: 10.1007/S00702-010-0438-Z |
0.753 |
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| 2010 |
Heneka MT. [Course modifying therapy of Alzheimer's dementia]. Der Nervenarzt. 81: 807-8, 810-4. PMID 20567962 DOI: 10.1007/S00115-010-3000-1 |
0.364 |
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| 2010 |
Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proceedings of the National Academy of Sciences of the United States of America. 107: 6058-63. PMID 20231476 DOI: 10.1073/Pnas.0909586107 |
0.737 |
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| 2010 |
Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochemistry International. 57: 375-82. PMID 20144675 DOI: 10.1016/J.Neuint.2010.02.001 |
0.726 |
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| 2010 |
Schlachetzki JC, Fiebich BL, Haake E, de Oliveira AC, Candelario-Jalil E, Heneka MT, Hüll M. Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia. Journal of Neuroinflammation. 7: 2. PMID 20064241 DOI: 10.1186/1742-2094-7-2 |
0.346 |
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| 2010 |
Heneka MT, RodrÃguez JJ, Verkhratsky A. Neuroglia in neurodegeneration. Brain Research Reviews. 63: 189-211. PMID 19944719 DOI: 10.1016/J.Brainresrev.2009.11.004 |
0.358 |
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| 2010 |
Heneka MT. The other brain Journal of Clinical Investigation. 120: 1789-1789. DOI: 10.1172/Jci43397 |
0.327 |
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| 2009 |
Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Schäfers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14177-84. PMID 19906966 DOI: 10.1523/Jneurosci.3238-09.2009 |
0.674 |
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| 2009 |
Jäger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU. alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. Journal of Neurochemistry. 111: 1369-82. PMID 19804379 DOI: 10.1111/J.1471-4159.2009.06420.X |
0.361 |
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| 2009 |
Papi A, Tatenhorst L, Terwel D, Hermes M, Kummer MP, Orlandi M, Heneka MT. PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models. Journal of Neurochemistry. 109: 1779-90. PMID 19457135 DOI: 10.1111/J.1471-4159.2009.06111.X |
0.649 |
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| 2009 |
Heneka MT, Nadrigny F, Regen T, Dumitrescu-Ozimek L, Jardanhazi-Kurutz D, Terwel D, Walter J, Hanisch UK, Kirchhoff F, Kummer MP. O4-02-06: Norepinephrine modulates salutary microglial functions in transgenic models of Alzheimer's disease Alzheimer's & Dementia. 5: P153-P153. DOI: 10.1016/J.Jalz.2009.05.527 |
0.685 |
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| 2009 |
Kummer MP, Hermes M, Hammerschmidt T, Terwel D, Gorji A, Pape H, Heneka MT. O1-05-07: iNOS gene deficiency modifies amyloid β
deposition, cognitive performance and hippocampal long-term potentiation in an APP transgenic mouse model Alzheimer's & Dementia. 5: P89-P89. DOI: 10.1016/J.Jalz.2009.05.229 |
0.665 |
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| 2009 |
Hammerschmidt T, Terwel D, Kummer M, Weinshenker D, Gorji A, Hermann S, Schäfers M, Pape H, Heneka MT. P4-235: Norepinephrine deficiency aggravates learning and memory impairment independent of amyloid-beta levels in APP PS1 mice Alzheimer's & Dementia. 5: P499-P499. DOI: 10.1016/J.Jalz.2009.04.701 |
0.662 |
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| 2008 |
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12097-106. PMID 19005074 DOI: 10.1523/Jneurosci.2635-08.2008 |
0.38 |
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| 2008 |
Seufert S, Coras R, Tränkle C, Zlotos DP, Blümcke I, Tatenhorst L, Heneka MT, Hahnen E. PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion. Ppar Research. 2008: 513943. PMID 18815619 DOI: 10.1155/2008/513943 |
0.317 |
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| 2008 |
Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. Journal of Neuroinflammation. 5: 38. PMID 18793399 DOI: 10.1186/1742-2094-5-38 |
0.664 |
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| 2008 |
Kummer MP, Heneka MT. PPARs in Alzheimer's Disease. Ppar Research. 2008: 403896. PMID 18645613 DOI: 10.1155/2008/403896 |
0.751 |
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| 2008 |
Landreth G, Jiang Q, Mandrekar S, Heneka M. PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 5: 481-9. PMID 18625459 DOI: 10.1016/J.Nurt.2008.05.003 |
0.493 |
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| 2008 |
Winkeler A, Waerzeggers Y, Klose A, Monfared P, Thomas AV, Schubert M, Heneka MT, Jacobs AH. Imaging noradrenergic influence on amyloid pathology in mouse models of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 35: S107-13. PMID 18219484 DOI: 10.1007/S00259-007-0710-0 |
0.302 |
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| 2008 |
Jiang Q, Heneka M, Landreth GE. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. Cns Drugs. 22: 1-14. PMID 18072811 DOI: 10.2165/00023210-200822010-00001 |
0.496 |
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| 2008 |
Heneka M, Dumitrescu-Ozimek L, Terwel D, Clermont-Timmer M, Tatenhorst L, Walter J, Kummer M. Norepinephrine induces a samaritan phenotype of microglia in an Alzheimer disease mouse model Aktuelle Neurologie. 35. DOI: 10.1055/s-0028-1086724 |
0.326 |
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| 2008 |
Krauthausen M, Carter S, Sarris M, Wakefield D, Heneka M, Campbell I, Müller M. CXCR3 promotes cerebellar inflammation but prevents ocular destruction in transgenic mice with a TH1-driven neuroinflammation Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086722 |
0.335 |
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| 2008 |
Feinstein DL, Brosnan CF, Whitacre CC, Landreth GE, Gavrilyuk V, Heneka MT. PPAR-agonists prevent experimental autoimmune encephalomyelitis Journal of Neurochemistry. 81: 36-36. DOI: 10.1046/J.1471-4159.81.S1.81.X |
0.729 |
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| 2007 |
Heneka MT, Landreth GE, Hüll M. Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders. Nature Clinical Practice. Neurology. 3: 496-504. PMID 17805244 DOI: 10.1038/Ncpneuro0586 |
0.468 |
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| 2007 |
Heneka MT, Landreth GE. PPARs in the brain. Biochimica Et Biophysica Acta. 1771: 1031-45. PMID 17569578 DOI: 10.1016/J.Bbalip.2007.04.016 |
0.491 |
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| 2007 |
Semmler A, Frisch C, Debeir T, Ramanathan M, Okulla T, Klockgether T, Heneka MT. Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model. Experimental Neurology. 204: 733-40. PMID 17306796 DOI: 10.1016/J.Expneurol.2007.01.003 |
0.307 |
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| 2007 |
Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. Journal of Neuroimmunology. 184: 69-91. PMID 17222916 DOI: 10.1016/J.Jneuroim.2006.11.017 |
0.48 |
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| 2007 |
Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiology of Aging. 28: 1206-14. PMID 16837104 DOI: 10.1016/J.Neurobiolaging.2006.06.003 |
0.769 |
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| 2006 |
Wahle T, Thal DR, Sastre M, Rentmeister A, Bogdanovic N, Famulok M, Heneka MT, Walter J. GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12838-46. PMID 17151287 DOI: 10.1523/Jneurosci.1982-06.2006 |
0.424 |
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| 2006 |
Hüll M, Berger M, Heneka M. Disease-modifying therapies in Alzheimer's disease: how far have we come? Drugs. 66: 2075-93. PMID 17112302 DOI: 10.2165/00003495-200666160-00004 |
0.435 |
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| 2006 |
Grommes C, Landreth GE, Sastre M, Beck M, Feinstein DL, Jacobs AH, Schlegel U, Heneka MT. Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment. Molecular Pharmacology. 70: 1524-33. PMID 16887936 DOI: 10.1124/Mol.106.022194 |
0.554 |
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| 2006 |
Ambrée O, Leimer U, Herring A, Görtz N, Sachser N, Heneka MT, Paulus W, Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. The American Journal of Pathology. 169: 544-52. PMID 16877355 DOI: 10.2353/Ajpath.2006.051107 |
0.466 |
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| 2006 |
Sundararajan S, Jiang Q, Heneka M, Landreth G. PPARgamma as a therapeutic target in central nervous system diseases. Neurochemistry International. 49: 136-44. PMID 16766086 DOI: 10.1016/J.Neuint.2006.03.020 |
0.4 |
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| 2006 |
Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 24: 167-76. PMID 16472958 DOI: 10.1016/J.Ijdevneu.2005.11.014 |
0.507 |
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| 2006 |
Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1343-54. PMID 16452658 DOI: 10.1523/Jneurosci.4236-05.2006 |
0.477 |
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| 2006 |
Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 103: 443-8. PMID 16407166 DOI: 10.1073/Pnas.0503839103 |
0.413 |
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| 2006 |
Betts MJ, Cardenas-Blanco A, Kanowski M, Wagner M, Heneka M, Spottke A, Teipel SJ, Schneider A, Oliver P, Priller J, Wiltfang J, Laske C, Jessen F, Düzel E. F4-07-03: RELATIONSHIP BETWEEN LOCUS COERULEUS MRI CONTRAST, COGNITION AND CSF BIOMARKERS IN AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1393-P1393. DOI: 10.1016/J.Jalz.2018.06.2890 |
0.351 |
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| 2006 |
Düzel E, Berron D, Cardenas-Blanco A, Metzger CD, Bittner D, Spottke A, Buerger K, Fliessbach K, Heneka M, Nestor P, Laske C, Peters O, Priller J, Schneider A, Speck O, et al. F1-04-02: ASSOCIATION BETWEEN NEURAL NOVELTY RESPONSES AND CSF BIOMARKERS OF ALZHEIMER'S DISEASE: ANATOMICAL SPECIFICITY AND DEPENDENCE ON ATROPHY Alzheimer's & Dementia. 14: P206-P207. DOI: 10.1016/J.Jalz.2018.06.2316 |
0.359 |
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| 2006 |
Metzger CD, Dyrba M, Bittner D, Hu X, Jessen F, Teipel SJ, Grothe M, Oliver P, Menne F, Fuentes M, Priller J, Spruth E, Franke C, Schneider A, Fließbach K, ... ... Heneka MT, et al. P2-431: RELATIONSHIP BETWEEN LOCAL RESTING STATE ACTIVITY, β-AMYLOID DEPOSITION AND MEMORY PERFORMANCE IN THE DZNE: LONGITUDINAL COGNITIVE IMPAIRMENT AND DEMENTIA STUDY (DELCODE) Alzheimer's & Dementia. 14: P877-P878. DOI: 10.1016/J.Jalz.2018.06.1123 |
0.328 |
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| 2006 |
Wahle T, Sastre M, Thal DR, Rentmeister A, Bogdanovic N, Famulok M, Heneka MT, Walter J. P4-011: Expression of GGA1 is altered in Alzheimer’s disease and regulates the generation of amyloid β-peptide Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1749 |
0.336 |
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| 2006 |
Heneka MT, Leimer U, Van Leuven F, Sastre M, Dumitrescu-Ozimek L, Feinstein DL. P3-283: Differential regulation of microglial cytokine production, phagocytosis and migration by norepinephrine: How locus ceruleus degeneration affects Alzheimer disease Alzheimer's & Dementia. 2: S458-S459. DOI: 10.1016/J.Jalz.2006.05.1552 |
0.593 |
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| 2006 |
Sastre M, Walter J, Klockgether T, Heneka MT. P3-269: Stimulation with norepinephrine induces a reduction of amyloid-β levels in neuronal cells under inflammatory conditions Alzheimer's & Dementia. 2: S454-S454. DOI: 10.1016/J.Jalz.2006.05.1538 |
0.345 |
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| 2006 |
Heneka MT. Inflammation in Alzheimer's disease Clinical Neuroscience Research. 6: 247-260. DOI: 10.1016/J.Cnr.2006.09.005 |
0.467 |
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| 2005 |
Heneka MT, Sastre M, Dumitrescu-Ozimek L, Dewachter I, Walter J, Klockgether T, Van Leuven F. Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice. Journal of Neuroinflammation. 2: 22. PMID 16212664 DOI: 10.1186/1742-2094-2-22 |
0.477 |
|
| 2005 |
Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T, Heneka MT. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. Journal of Immunology (Baltimore, Md. : 1950). 175: 4948-55. PMID 16210596 DOI: 10.4049/Jimmunol.175.8.4948 |
0.32 |
|
| 2005 |
Semmler A, Okulla T, Sastre M, Dumitrescu-Ozimek L, Heneka MT. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. Journal of Chemical Neuroanatomy. 30: 144-57. PMID 16122904 DOI: 10.1016/J.Jchemneu.2005.07.003 |
0.35 |
|
| 2005 |
Schütz B, Reimann J, Dumitrescu-Ozimek L, Kappes-Horn K, Landreth GE, Schürmann B, Zimmer A, Heneka MT. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7805-12. PMID 16120782 DOI: 10.1523/Jneurosci.2038-05.2005 |
0.361 |
|
| 2005 |
Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide. The Journal of Biological Chemistry. 280: 28110-7. PMID 15923191 DOI: 10.1074/Jbc.M414525200 |
0.356 |
|
| 2005 |
Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain : a Journal of Neurology. 128: 1442-53. PMID 15817521 DOI: 10.1093/Brain/Awh452 |
0.502 |
|
| 2004 |
Lacombe P, Mathews PM, Schmidt SD, Breidert T, Heneka MT, Landreth GE, Feinstein DL, Galea E. Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. Journal of Neuroinflammation. 1: 11. PMID 15285804 DOI: 10.1186/1742-2094-1-11 |
0.635 |
|
| 2004 |
Pershadsingh HA, Heneka MT, Saini R, Amin NM, Broeske DJ, Feinstein DL. Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. Journal of Neuroinflammation. 1: 3. PMID 15285799 DOI: 10.1186/1742-2094-1-3 |
0.542 |
|
| 2004 |
Grommes C, Landreth GE, Heneka MT. Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. The Lancet. Oncology. 5: 419-29. PMID 15231248 DOI: 10.1016/S1470-2045(04)01509-8 |
0.315 |
|
| 2004 |
Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. Journal of Neurochemistry. 88: 494-501. PMID 14690537 DOI: 10.1046/J.1471-4159.2003.02210.X |
0.396 |
|
| 2004 |
Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. Journal of Leukocyte Biology. 75: 478-85. PMID 14657213 DOI: 10.1189/Jlb.0803402 |
0.569 |
|
| 2004 |
Dewachter I, Rosen E, Landreth G, Willson T, Klockgether T, Van Leuven F, Heneka M. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists modulate immunostimulated processing of APP through regulation of beta-secretase (BACE) Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-833264 |
0.316 |
|
| 2004 |
Sastre M, Dewachter I, Rosen E, Klockgether T, van Leuven F, Heneka MT. P4-203 Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists modulate immunostimulated processing of APP through regulation of β-secretase (BACE) Neurobiology of Aging. 25: S533. DOI: 10.1016/S0197-4580(04)81761-5 |
0.305 |
|
| 2004 |
Feinstein DL, Heneka MT, Kalinin S, Chauhan N, Gavrilyuk V. O3-04-04 Cortical noradrenergic depletion accelerates pathology in TGAPP mice Neurobiology of Aging. 25: S60. DOI: 10.1016/S0197-4580(04)80201-X |
0.68 |
|
| 2003 |
Pedraza CE, Baltrons MA, Heneka MT, GarcÃa A. Interleukin-1 beta and lipopolysaccharide decrease soluble guanylyl cyclase in brain cells: NO-independent destabilization of protein and NO-dependent decrease of mRNA. Journal of Neuroimmunology. 144: 80-90. PMID 14597101 DOI: 10.1016/J.Jneuroim.2003.08.034 |
0.308 |
|
| 2003 |
Sastre M, Dewachter I, Landreth GE, Willson TM, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9796-804. PMID 14586007 |
0.343 |
|
| 2003 |
Galea E, Heneka MT, Dello Russo C, Feinstein DL. Intrinsic regulation of brain inflammatory responses. Cellular and Molecular Neurobiology. 23: 625-35. PMID 14514020 DOI: 10.1023/A:1025084415833 |
0.745 |
|
| 2003 |
Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. Journal of Neurochemistry. 86: 907-16. PMID 12887689 DOI: 10.1046/J.1471-4159.2003.01909.X |
0.758 |
|
| 2003 |
Harzheim M, Altenschmidt M, Heneka MT, Schröder R, Klockgether T, Schmidt S. IFN-beta1a (Rebif) modifies the expression of microfilament-associated cell-cell contacts in C6 glioma cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 83-9. PMID 12744773 DOI: 10.1089/107999003321455471 |
0.334 |
|
| 2003 |
Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. Journal of Neurochemistry. 85: 387-98. PMID 12675915 DOI: 10.1046/J.1471-4159.2003.01694.X |
0.742 |
|
| 2002 |
Feinstein DL, Heneka MT, Gavrilyuk V, Dello Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochemistry International. 41: 357-65. PMID 12176079 DOI: 10.1016/S0197-0186(02)00049-9 |
0.81 |
|
| 2002 |
Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. Journal of Neurochemistry. 82: 615-24. PMID 12153485 DOI: 10.1046/J.1471-4159.2002.00990.X |
0.355 |
|
| 2002 |
Baltrons MA, Pedraza CE, Heneka MT, GarcÃa A. Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells. Neurobiology of Disease. 10: 139-49. PMID 12127152 DOI: 10.1006/Nbdi.2002.0492 |
0.372 |
|
| 2002 |
Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G, Heneka MT. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Annals of Neurology. 51: 694-702. PMID 12112074 DOI: 10.1002/Ana.10206 |
0.729 |
|
| 2002 |
Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. Journal of Neurochemistry. 81: 1052-60. PMID 12065618 DOI: 10.1046/J.1471-4159.2002.00899.X |
0.547 |
|
| 2002 |
Gavrilyuk V, Dello Russo C, Heneka MT, Pelligrino D, Weinberg G, Feinstein DL. Norepinephrine increases I kappa B alpha expression in astrocytes. The Journal of Biological Chemistry. 277: 29662-8. PMID 12050158 DOI: 10.1074/Jbc.M203256200 |
0.763 |
|
| 2002 |
Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2434-42. PMID 11923407 DOI: 10.1046/J.1471-4159.81.S1.20_10.X |
0.647 |
|
| 2002 |
Murphy P, Sharp A, Shin J, Gavrilyuk V, Dello Russo C, Weinberg G, Sharp FR, Lu A, Heneka MT, Feinstein DL. Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 67: 461-70. PMID 11835313 DOI: 10.1002/Jnr.10139 |
0.799 |
|
| 2002 |
Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic Depletion Potentiates β-Amyloid-Induced Cortical Inflammation: Implications for Alzheimer's Disease The Journal of Neuroscience. 22: 2434-2442. DOI: 10.1523/Jneurosci.22-07-02434.2002 |
0.642 |
|
| 2001 |
Landreth GE, Heneka MT. Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease. Neurobiology of Aging. 22: 937-44. PMID 11755002 DOI: 10.1016/S0197-4580(01)00296-2 |
0.467 |
|
| 2001 |
Heneka MT, Wiesinger H, Dumitrescu-Ozimek L, Riederer P, Feinstein DL, Klockgether T. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 906-16. PMID 11556547 DOI: 10.1093/Jnen/60.9.906 |
0.615 |
|
| 2001 |
Heneka MT, Sharp A, Murphy P, Lyons JA, Dumitrescu L, Feinstein DL. The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice. Journal of Neurochemistry. 77: 568-79. PMID 11299319 DOI: 10.1046/J.1471-4159.2001.00260.X |
0.616 |
|
| 2001 |
Heneka MT, Feinstein DL. Expression and function of inducible nitric oxide synthase in neurons. Journal of Neuroimmunology. 114: 8-18. PMID 11240010 DOI: 10.1016/S0165-5728(01)00246-6 |
0.563 |
|
| 2001 |
Heneka MT, Landreth GE, Feinstein DL. Role for peroxisome proliferator-activated receptor-gamma in Alzheimer's disease. Annals of Neurology. 49: 276. PMID 11220752 DOI: 10.1002/1531-8249(20010201)49:2<276::Aid-Ana53>3.0.Co;2-5 |
0.614 |
|
| 2000 |
Heneka MT, Klockgether T, Feinstein DL. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6862-7. PMID 10995830 |
0.591 |
|
| 2000 |
Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL. The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 800-11. PMID 10826530 DOI: 10.1097/00004647-200005000-00006 |
0.721 |
|
| 2000 |
Heneka MT, Dumitrescu L, Löschmann PA, Wüllner U, Klockgether T. Temporal, regional, and cell-specific changes of iNOS expression after intrastriatal microinjection of interferon gamma and bacterial lipopolysaccharide. Journal of Chemical Neuroanatomy. 18: 167-79. PMID 10781735 DOI: 10.1016/S0891-0618(00)00041-7 |
0.322 |
|
| 2000 |
Heneka MT, Klockgether T, Feinstein DL. Peroxisome Proliferator-Activated Receptor-γ Ligands Reduce Neuronal Inducible Nitric Oxide Synthase Expression and Cell DeathIn Vivo The Journal of Neuroscience. 20: 6862-6867. DOI: 10.1523/Jneurosci.20-18-06862.2000 |
0.628 |
|
| 1999 |
Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wüllner U, Klockgether T. Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. Journal of Neuroimmunology. 100: 156-68. PMID 10695726 DOI: 10.1016/S0165-5728(99)00192-7 |
0.605 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2005 |
Grommes C, Landreth GE, Schlegel U, Heneka MT. The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells. The Journal of Pharmacology and Experimental Therapeutics. 313: 806-13. PMID 15665144 DOI: 10.1124/Jpet.104.078972 |
0.298 |
|
| 2023 |
Karabag D, Scheiblich H, Griep A, Santarelli F, Schwartz S, Heneka MT, Ising C. Characterizing microglial senescence: Tau as a key player. Journal of Neurochemistry. PMID 37278117 DOI: 10.1111/jnc.15866 |
0.298 |
|
| 2023 |
Kapadia A, Theil S, Opitz S, Villacampa N, Beckert H, Schoch-McGovern S, Heneka MT, Kumar S, Walter J. Phosphorylation-state dependent intraneuronal sorting of Aβ differentially impairs autophagy and the endo-lysosomal system. Autophagy. PMID 37642583 DOI: 10.1080/15548627.2023.2252300 |
0.296 |
|
| 2023 |
Walker KA, Le Page LM, Terrando N, Duggan MR, Heneka MT, Bettcher BM. The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap. Molecular Neurodegeneration. 18: 37. PMID 37277738 DOI: 10.1186/s13024-023-00627-2 |
0.296 |
|
| 2017 |
Kemmerling N, Wunderlich P, Theil S, Linnartz-Gerlach B, Hersch N, Hoffmann B, Heneka MT, de Strooper B, Neumann H, Walter J. Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. Glia. PMID 28370426 DOI: 10.1002/Glia.23147 |
0.296 |
|
| 2016 |
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, et al. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine. 8: 333ra50. PMID 27053774 DOI: 10.1126/Scitranslmed.Aad6100 |
0.295 |
|
| 2014 |
Korte M, Faiz S, Heneka M. P1-003: MICROGLIA ACTIVATION COMPROMISES NEURONAL AUTOPHAGY THROUGH A NLRP3 INFLAMMASOME-MEDIATED MECHANISM Alzheimer's & Dementia. 10: P305-P305. DOI: 10.1016/J.Jalz.2014.05.238 |
0.294 |
|
| 2013 |
Semmler A, Widmann CN, Okulla T, Urbach H, Kaiser M, Widman G, Mormann F, Weide J, Fliessbach K, Hoeft A, Jessen F, Putensen C, Heneka MT. Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 62-9. PMID 23134661 DOI: 10.1136/Jnnp-2012-302883 |
0.294 |
|
| 2022 |
Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, ... ... Heneka MT, et al. Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. 99: e775-e788. PMID 35995589 DOI: 10.1212/WNL.0000000000200667 |
0.29 |
|
| 2008 |
Tatenhorst L, Hahnen E, Heneka MT. Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors. Ppar Research. 2008: 204514. PMID 18725982 DOI: 10.1155/2008/204514 |
0.288 |
|
| 2014 |
Heneka MT. Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction. The Journal of Experimental Medicine. 211: 1500. PMID 25071159 DOI: 10.1084/Jem.2118Insight1 |
0.287 |
|
| 2014 |
Fink A, Heneka M, Doblhammer G. The Effect Of The Prescription Of Pioglitazone On The Incidence Of Dementia Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.973 |
0.287 |
|
| 2021 |
Ballarini T, Melo van Lent D, Brunner J, Schröder A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, ... ... Heneka MT, et al. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. PMID 33952652 DOI: 10.1212/WNL.0000000000012067 |
0.287 |
|
| 2022 |
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Heneka MT, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z |
0.287 |
|
| 2022 |
Ersoezlue E, Rauchmann BS, Schneider-Axmann T, Wagner M, Ballarini T, Tato M, Utecht J, Kurz C, Papazov B, Guersel S, Burow L, Koller G, Stöcklein S, Keeser D, Bartels C, ... ... Heneka MT, et al. Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease. Neurobiology of Aging. 122: 33-44. PMID 36476760 DOI: 10.1016/j.neurobiolaging.2022.05.015 |
0.286 |
|
| 2023 |
Dadwal S, Heneka MT. Microglia heterogeneity in health and disease. Febs Open Bio. PMID 37945346 DOI: 10.1002/2211-5463.13735 |
0.285 |
|
| 2008 |
Terwel D, Heneka M. GSK-3beta activation mediates Abeta induced tau pathology in multiple transgenic mice Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086929 |
0.285 |
|
| 2017 |
Karaca I, Walliser C, Wagner H, Rüther E, Frölich L, Peters O, Hüll M, Popp J, Lewczuk P, Kornhuber J, Wiltfang J, Heneka M, Walter J, Jessen F, Maier W, et al. FUNCTIONAL CHARACTERIZATION OF A RARE GENETIC VARIANT IN PHOSPHOLIPASE Cγ2 WHICH IS ASSOCIATED WITH A BENEFICIAL EFFECT ON THE PROGRESSION OF ALZHEIMER’S DISEASE Alzheimers & Dementia. 13: 997. DOI: 10.1016/J.Jalz.2017.06.1376 |
0.284 |
|
| 2013 |
Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, Müller M. CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia. Plos One. 8: e57307. PMID 23468966 DOI: 10.1371/Journal.Pone.0057307 |
0.284 |
|
| 2022 |
Düzel E, Ziegler G, Berron D, Maass A, Schütze H, Cardenas-Blanco A, Glanz W, Metzger C, Dobisch L, Reuter M, Spottke A, Brosseron F, Fliessbach K, Heneka MT, Laske C, et al. Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction. Brain : a Journal of Neurology. PMID 35352105 DOI: 10.1093/brain/awab405 |
0.284 |
|
| 2019 |
Heneka MT, McManus RM, Latz E. Author Correction: Inflammasome signalling in brain function and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 30742056 DOI: 10.1038/S41583-019-0137-1 |
0.28 |
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| 2008 |
Löschmann Y, Terwel D, Hoffmann E, Cantz T, Schöler H, Heneka M. Neuroinflammatory and behavioural changes in Atp7b knockout mice, an animal model for Morbus Wilson Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086635 |
0.279 |
|
| 2007 |
Kummer C, Winkeler A, Dittmar C, Bauer B, Rueger MA, Rueckriem B, Heneka MT, Vollmar S, Wienhard K, Fraefel C, Heiss WD, Jacobs AH. Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector. Molecular Imaging. 6: 181-92. PMID 17532884 DOI: 10.2310/7290.2007.00015 |
0.278 |
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| 2023 |
Bartsch T, Berg D, Heneka M, Leypoldt F. [Parkinson's and Alzheimer's disease as system-wide neurodegenerative disorders]. Der Nervenarzt. 94: 875-884. PMID 37672086 DOI: 10.1007/s00115-023-01542-z |
0.278 |
|
| 2013 |
Gaikwad SM, Heneka MT. Studying M1 and M2 states in adult microglia. Methods in Molecular Biology (Clifton, N.J.). 1041: 185-97. PMID 23813380 DOI: 10.1007/978-1-62703-520-0_18 |
0.277 |
|
| 2018 |
Villacampa N, Heneka MT. Microglia: You'll Never Walk Alone! Immunity. 48: 195-197. PMID 29466750 DOI: 10.1016/J.Immuni.2018.02.009 |
0.273 |
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| 2008 |
Weberpals M, Hermes M, Hermann S, Semmler A, Kummer M, Terwel D, Schütz B, Schäfers M, Heneka M. iNOS gene deficiency protects from sepsis induced cognitive long-term deficits Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086922 |
0.272 |
|
| 2008 |
Hammerschmidt T, Kummer M, Gorji A, Terwel D, Weinshenker D, Pape H, Heneka M. Noradreneline deficiency aggrevates learning and memory impairment independent of Aß Levels in APPPS1 mice Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086716 |
0.27 |
|
| 2006 |
McManus RM, Heneka MT. S3-02-03: NEUROINFLAMMATORY PROCESSES AND NEURODEGENERATION Alzheimer's & Dementia. 14: P995-P995. DOI: 10.1016/J.Jalz.2018.06.2737 |
0.27 |
|
| 2018 |
Miebach L, Wolfsgruber S, Frommann I, Roeske S, Oliver P, Buerger K, Nestor P, Ewers M, Laske C, Priller J, Schneider A, Spottke A, Heneka M, Teipel SJ, Wiltfang J, et al. F4-08-04: Subjective Cognitive Decline, As Measured With A Structured Interview, Is Related To Amyloid Pathology In Cognitively Healthy Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2895 |
0.27 |
|
| 2022 |
Nemy M, Dyrba M, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Goerss D, Heneka MT, Hetzer S, Incesoy EI, Janowitz D, Kilimann I, et al. Cholinergic white matter pathways along the Alzheimer's disease continuum. Brain : a Journal of Neurology. PMID 36288546 DOI: 10.1093/brain/awac385 |
0.269 |
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| 2024 |
Ravichandran KA, Heneka MT. Inflammasomes in neurological disorders - mechanisms and therapeutic potential. Nature Reviews. Neurology. PMID 38195712 DOI: 10.1038/s41582-023-00915-x |
0.268 |
|
| 2019 |
Mercan D, Heneka MT. Norepinephrine as a modulator of microglial dynamics. Nature Neuroscience. PMID 31636450 DOI: 10.1038/S41593-019-0526-9 |
0.267 |
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| 2017 |
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, et al. A guiding map for inflammation. Nature Immunology. 18: 826-831. PMID 28722720 DOI: 10.1038/Ni.3790 |
0.266 |
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| 2022 |
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, ... ... Heneka MT, et al. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. Jama Neurology. PMID 35099509 DOI: 10.1001/jamaneurol.2021.5216 |
0.266 |
|
| 2023 |
Braatz C, Komes MP, Ravichandran KA, de Fragas MG, Griep A, Schwartz S, McManus RM, Heneka MT. NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro. Journal of Neurochemistry. PMID 36799439 DOI: 10.1111/jnc.15778 |
0.262 |
|
| 2023 |
Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, et al. APOE and immunity: Research highlights. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36975090 DOI: 10.1002/alz.13020 |
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Löschmann PA, Wüllner U, Heneka MT, Schulz JB, Kunow M, Wachtel H, Klockgether T. Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease. Synapse (New York, N.Y.). 26: 381-91. PMID 9215597 DOI: 10.1002/(Sici)1098-2396(199708)26:4<381::Aid-Syn6>3.0.Co;2-2 |
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| 2020 |
Traschütz A, Enkirch SJ, Polomac N, Widmann CN, Schild HH, Heneka MT, Hattingen E. The Entorhinal Cortex Atrophy Score Is Diagnostic and Prognostic in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 32250289 DOI: 10.3233/Jad-181150 |
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| 2023 |
Stratoulias V, Ruiz R, Kanatani S, Osman AM, Keane L, Armengol JA, Rodríguez-Moreno A, Murgoci AN, García-Domínguez I, Alonso-Bellido I, González Ibáñez F, Picard K, Vázquez-Cabrera G, Posada-Pérez M, Vernoux N, ... ... Heneka MT, et al. ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Nature Neuroscience. PMID 37169859 DOI: 10.1038/s41593-023-01326-3 |
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| 2023 |
Heneka MT. ApoE4 makes microglia trembling. Neuron. 111: 142-144. PMID 36657395 DOI: 10.1016/j.neuron.2022.12.032 |
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| 2019 |
Bainbridge WA, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Dobisch L, Bittner D, Glanz W, Spottke A, Rudolph J, Brosseron F, Buerger K, Janowitz D, Fliessbach K, Heneka M, et al. Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 610-618. PMID 31517023 DOI: 10.1016/J.Dadm.2019.07.005 |
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Berron D, Cardenas-Blanco A, Bittner D, Metzger CD, Spottke A, Heneka M, Fließbach K, Schneider A, Teipel SJ, Wagner M, Speck O, Jessen F, Düzel E. Ic-P-084: Effects Of Age And Csf Measures Of Tau On Mnemonic Discrimination Of Objects And Scenes In Medial Temporal Lobe Pathways Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1126 |
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Winkeler A, Sena-Esteves M, Paulis LE, Li H, Waerzeggers Y, Rückriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, et al. Switching on the lights for gene therapy. Plos One. 2: e528. PMID 17565381 DOI: 10.1371/Journal.Pone.0000528 |
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Lehmer C, Schludi MH, Ransom L, Greiling J, Junghänel M, Exner N, Riemenschneider H, van der Zee J, Van Broeckhoven C, Weydt P, Heneka MT, Edbauer D. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. Embo Molecular Medicine. PMID 29789341 DOI: 10.15252/Emmm.201708558 |
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| 2013 |
Okroglic S, Widmann CN, Urbach H, Scheltens P, Heneka MT. Clinical symptoms and risk factors in cerebral microangiopathy patients. Plos One. 8: e53455. PMID 23393549 DOI: 10.1371/Journal.Pone.0053455 |
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| 2015 |
Draffin JE, Knafo S, Heneka MT. Alzheimer's Disease and Mechanism-Based Attempts to Enhance Cognition Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors. 193-231. DOI: 10.1016/B978-0-12-417042-1.00009-7 |
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| 2018 |
Berron D, Cardenas-Blanco A, Bittner D, Metzger CD, Spottke A, Heneka M, Fließbach K, Schneider A, Teipel SJ, Wagner M, Speck O, Jessen F, Düzel E. F1-04-03: Effects Of Age And Tau Measured In Csf On Mnemonic Discrimination Of Objects And Scenes In Medial Temporal Lobe Pathways Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2317 |
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van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Mat?j R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, ... ... Heneka MT, et al. Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration. Acta Neuropathologica. 128: 397-410. PMID 24899140 DOI: 10.1007/S00401-014-1298-7 |
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| 2021 |
Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, et al. Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cerebral Cortex (New York, N.Y. : 1991). PMID 34080613 DOI: 10.1093/cercor/bhab130 |
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| 2020 |
Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, et al. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimer's Research & Therapy. 12: 131. PMID 33066827 DOI: 10.1186/s13195-020-00701-7 |
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Widmann CN, Schewe JC, Heneka MT. Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply. The Lancet. Neurology. 13: 968-9. PMID 25231518 DOI: 10.1016/S1474-4422(14)70204-2 |
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Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, Röske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Fließbach K, Schneider A, Wiltfang J, Bartels C, ... ... Heneka MT, et al. Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35275535 DOI: 10.3233/JAD-215416 |
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Widmann CN, Sinning J, Ghanem A, Brosseron F, Heneka M, Wagner M. Chronic And Acute Systemic Inflammation And Long-Term Cognitive Decline Alzheimers & Dementia. 13: 640. DOI: 10.1016/J.Jalz.2017.06.737 |
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| 2022 |
Jessen F, Wolfsgruber S, Kleineindam L, Spottke A, Altenstein S, Bartels C, Berger M, Brosseron F, Daamen M, Dichgans M, Dobisch L, Ewers M, Fenski F, Fliessbach K, Freiesleben SD, ... ... Heneka MT, et al. Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35451563 DOI: 10.1002/alz.12674 |
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Heneka MT. Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients. Experimental Neurology. 217: 237-9. PMID 19328200 DOI: 10.1016/J.Expneurol.2009.03.013 |
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de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Heneka MT, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8 |
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van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, Bäumer V, Engelborghs S, De Bleecker J, Baets J, Gelpi E, Rojas-García R, Clarimón J, Lleó A, Diehl-Schmid J, ... ... Heneka MT, et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort With Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Human Mutation. PMID 28008748 DOI: 10.1002/Humu.23161 |
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Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, ... ... Heneka MT, et al. Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression. International Journal of Geriatric Psychiatry. 38: e6007. PMID 37800601 DOI: 10.1002/gps.6007 |
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Wolfsgruber S, Kleineidam L, Roeske S, Zulka L, Buerger K, Ewers M, Christoph L, Peters O, Priller J, Nestor P, Schneider A, Spottke A, Ramirez A, Heneka M, Wiltfang J, et al. P1-028: Occupational Cognitive Requirements Are An Important Proxy Measure Of Cognitive Reserve: Evidence From The Agecode And Delcode Studies Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.029 |
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Bettcher BM, Tansey MG, Dorothée G, Heneka MT. Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nature Reviews. Neurology. PMID 34522039 DOI: 10.1038/s41582-021-00549-x |
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Semmler A, Okulla T, Kaiser M, Seifert B, Heneka MT. Long-term neuromuscular sequelae of critical illness. Journal of Neurology. 260: 151-7. PMID 22820684 DOI: 10.1007/S00415-012-6605-4 |
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Wolfsgruber S, Kleineidam L, Peters O, Buerger K, Ewers M, Priller J, Laske C, Teipel SJ, Schneider A, Spottke A, Heneka MT, Wiltfang J, Jessen F, Wagner M. P3-447: Minor Neuropsychological Deficits In Cognitively Normal Older Individuals With Subjective Cognitive Decline: Results From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3481 |
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Traschütz A, Heneka MT. Neuroinflammation in Neurodegenerative Disease | Neuroinflammation bei neurodegenerativen Erkrankungen Aktuelle Neurologie. 42: 402-410. DOI: 10.1055/s-0035-1552714 |
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Lindlau A, Widmann CN, Putensen C, Jessen F, Semmler A, Heneka MT. Predictors of hippocampal atrophy in critically ill patients. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 410-5. PMID 24724819 DOI: 10.1111/Ene.12443 |
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Jacobs AH, Rueger MA, Winkeler A, Li H, Vollmar S, Waerzeggers Y, Rueckriem B, Kummer C, Dittmar C, Klein M, Heneka MT, Herrlinger U, Fraefel C, Graf R, Wienhard K, et al. Imaging-guided gene therapy of experimental gliomas. Cancer Research. 67: 1706-15. PMID 17308112 DOI: 10.1158/0008-5472.Can-06-2418 |
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Ziegler G, Penny WD, Berron D, Cardenas-Blanco A, Betts MJ, Schütze H, Heneka M, Fliessbach K, Teipel SJ, Wagner M, Spottke A, Nestor P, Buerger K, Schneider A, Peters O, et al. [P2-074]: MODELING OF HIDDEN CAUSES FOR DYNAMIC CHANGES IN STRUCTURAL INTEGRITY AND COGNITION IN SUBJECTIVE COGNITIVE DECLINE: A DELCODE PROJECT Alzheimer's & Dementia. 13: P634-P634. DOI: 10.1016/J.Jalz.2017.06.723 |
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Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann FJ, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, ... ... Heneka MT, et al. mTOR-dependent translation amplifies microglia priming in aging mice. The Journal of Clinical Investigation. PMID 33108356 DOI: 10.1172/JCI132727 |
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Heneka M. Neuroscience: Tide of forgetting Nature. 539: 166-167. DOI: 10.1038/539166A |
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Dupuis L, Dengler R, Heneka MT, Meyer T, Zierz S, Kassubek J, Fischer W, Steiner F, Lindauer E, Otto M, Dreyhaupt J, Grehl T, Hermann A, Winkler AS, Bogdahn U, et al. A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis. Plos One. 7: e37885. PMID 22715372 DOI: 10.1371/Journal.Pone.0037885 |
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Nitsch L, Petzinna S, Zimmermann J, Schneider L, Krauthausen M, Heneka MT, Getts DR, Becker A, Müller M. Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model. Journal of Neuroinflammation. 18: 101. PMID 33906683 DOI: 10.1186/s12974-021-02140-z |
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Hermes M, Kummer M, Hammerschmidt T, Terwel D, Pape H, Heneka M. iNOS gene deficiency modifies beta-amyloid deposition, cognitive performance and hippocampal long term potentiation in APPPS1 tg mice Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086926 |
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Widmann CN, Brosseron F, Spottke A, Wagner M, Putensen C, Hoeft A, Klockgether T, Heneka M. Long-Term Cognitive And Cerebral Outcome In Sepsis Survivors Alzheimers & Dementia. 10: 435. DOI: 10.1016/J.Jalz.2014.05.577 |
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Lage C, González-Suárez A, Puerto Alcalde-Hierro M, Isabel Sampedro-González M, Ángeles Villanueva-Eguaras M, Rubén Sánchez-Crespo M, Widmann C, Brosseron F, Pozueta A, López-García S, García-Martínez M, Kazimierczak M, Bravo-González M, Fernández-Rodríguez A, Drake-Pérez M, ... ... Heneka MT, et al. Major Surgery Affects Memory in Individuals with Cerebral Amyloid-β Pathology. Journal of Alzheimer's Disease : Jad. PMID 33361588 DOI: 10.3233/JAD-191229 |
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Yildirim Z, Delen F, Berron D, Baumeister H, Ziegler G, Schütze H, Glanz W, Dobisch L, Peters O, Freiesleben SD, Schneider LS, Priller J, Spruth EJ, Schneider A, Fliessbach K, ... ... Heneka M, et al. Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2. Alzheimer's Research & Therapy. 15: 43. PMID 36855049 DOI: 10.1186/s13195-023-01187-9 |
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Roeske S, Wolfsgruber S, Kleineidam L, Zulka L, Buerger K, Ewers M, Laske C, Nestor P, Peters O, Priller J, Schneider A, Spottke A, Ramirez A, Heneka M, Teipel SJ, et al. P3-591: A German Version Of The Lifetime Of Experiences Questionnaire (Leq) To Measure Cognitive Reserve: Validation Results From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1957 |
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Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, ... ... Heneka MT, et al. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nature Genetics. 46: 901-4. PMID 24997987 DOI: 10.1038/Ng.3029 |
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Thees C, Kaiser M, Scholz M, Semmler A, Heneka MT, Baumgarten G, Hoeft A, Putensen C. Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome. Critical Care (London, England). 11: R123. PMID 18045492 DOI: 10.1186/Cc6185 |
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Bettcher BM, Tansey MG, Dorothée G, Heneka MT. Publisher Correction: Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nature Reviews. Neurology. 17: 724. PMID 34625724 DOI: 10.1038/s41582-021-00579-5 |
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Ribon M, Leone C, Chiot A, Berriat F, Rampanana M, Cottin J, Bohl D, Millecamps S, Lobsiger CS, Heneka MT, Boillée S. Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1 ALS mice. Neurobiology of Aging. 101: 181-186. PMID 33626479 DOI: 10.1016/j.neurobiolaging.2021.01.015 |
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Heneka MT. Apoptosis in inflammation, Edited by James D. Winkler, Birkhäuser Verlag AG, Basel, Swizerland, 1999, 244 pages, price DM 228.00, ISBN 3-7643-5795-9 Journal of Chemical Neuroanatomy. 21: 251-252. DOI: 10.1016/S0891-0618(01)00102-8 |
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Miebach L, Kleineidam L, Peters O, Priller J, Buerger K, Perneczky R, Laske C, Schneider A, Heneka MT, Spottke A, Teipel SJ, Wiltfang J, Düzel E, Jessen F, Wagner M. P1-326: Anosognosia And Csf-Biomarkers In Nondemented Older Adults: Results From The Delcode-Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.881 |
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Heinzinger N, Maass A, Berron D, Yakupov R, Peters O, Fiebach J, Villringer K, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, ... ... Heneka MT, et al. Exploring the ATN classification system using brain morphology. Alzheimer's Research & Therapy. 15: 50. PMID 36915139 DOI: 10.1186/s13195-023-01185-x |
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Odoj K, Brawek B, Asavapanumas N, Mojtahedi N, Heneka MT, Garaschuk O. In vivo mechanisms of cortical network dysfunction induced by systemic inflammation. Brain, Behavior, and Immunity. PMID 34052361 DOI: 10.1016/j.bbi.2021.05.021 |
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Meiberth D, Burkei E, Block W, Scheef L, Schild HH, Heneka MT, Wagner M, Frommann I, Röske S, Hu X, Jessen F. Hippocampal Grey Matter Atrophy Is Associated With The Free And Cued Selective Reminding Test Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.253 |
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Hansen N, Singh A, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dobisch L, Dechent P, Ertl-Wagner BB, Fliessbach K, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, et al. Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline. Frontiers in Aging Neuroscience. 13: 626974. PMID 33967736 DOI: 10.3389/fnagi.2021.626974 |
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Henning L, Antony H, Breuer A, Müller J, Seifert G, Audinat E, Singh P, Brosseron F, Heneka MT, Steinhäuser C, Bedner P. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. PMID 36373840 DOI: 10.1002/glia.24265 |
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Heneka MT, Schmidlin A, Wiesinger H. Induction of argininosuccinate synthetase in rat brain glial cells after striatal microinjection of immunostimulants. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 898-907. PMID 10458597 DOI: 10.1097/00004647-199908000-00009 |
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Jessen F, Wolfsgruber S, Daamen M, Molinuevo JL, Teunissen CE, Rami L, Coll-Padros N, Bouwman FH, Slot RER, Sikkes SAM, Wesselman LMP, Peters O, Buerger K, Priller J, Laske C, ... ... Heneka MT, et al. P3-289: Harmonization Of Scd Operationalization Across Different Memory Clinic Settings: The Euro-Scd Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1649 |
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Kleineidam L, Wolfsgruber S, Weyrauch AS, Zulka LE, Forstmeier S, Roeske S, van den Bussche H, Kaduszkiewicz H, Wiese B, Weyerer S, Werle J, Fuchs A, Pentzek M, Brettschneider C, König HH, ... ... Heneka MT, et al. Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve. Frontiers in Psychology. 13: 957308. PMID 36571008 DOI: 10.3389/fpsyg.2022.957308 |
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Rieger J, Ständer M, Löschmann PA, Heneka M, Dichgans J, Klockgether T, Weller M. Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGF-beta, dexamethasone, and p53 gene transfer. Oncogene. 17: 2323-32. PMID 9811463 DOI: 10.1038/sj.onc.1202154 |
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Heneka MT. Nitric oxide: principles and actions, Jack Lancaster, Jr. (Editor). Academic Press, San Diego, USA, 1996, 355 pages, price $103.00, ISBN 0-12-435555-2 Journal of Chemical Neuroanatomy. 21: 249-250. DOI: 10.1016/S0891-0618(01)00104-1 |
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Dyrba M, Hanzig M, Altenstein S, Bader S, Ballarini T, Brosseron F, Buerger K, Cantré D, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Glanz W, Haynes JD, ... Heneka MT, et al. Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease. Alzheimer's Research & Therapy. 13: 191. PMID 34814936 DOI: 10.1186/s13195-021-00924-2 |
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Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MT. Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies. Journal of Immunology (Baltimore, Md. : 1950). PMID 34507948 DOI: 10.4049/jimmunol.2100035 |
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Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, ... ... Heneka MT, et al. Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline. Neurology. PMID 37821235 DOI: 10.1212/WNL.0000000000207844 |
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Schlitter M, Kappes-Horn K, Kornblum C, Klockgether T, Heneka M, Reimann J, Müller M. Charakterisierung von Makrophagen-Populationen in humanen Myopathien Aktuelle Neurologie. 36: 726. DOI: 10.1055/S-0029-1238819 |
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Kummer M, Hermes M, Hülsmann C, Hammerschmidt T, Tatenhorst L, Terwel D, Ortler S, Kroner A, Wiendl H, Heneka M. Implications of the PD-1/B7-H1 receptor-ligand system in Alzheimer's Disease Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086921 |
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Manabe T, Heneka MT. Cerebral dysfunctions caused by sepsis during ageing. Nature Reviews. Immunology. PMID 34764472 DOI: 10.1038/s41577-021-00643-7 |
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Jiang S, Maphis NM, Binder J, Chisholm D, Weston L, Duran W, Peterson C, Zimmerman A, Mandell MA, Jett SD, Bigio E, Geula C, Mellios N, Weick JP, Rosenberg GA, ... ... Heneka MT, et al. Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway. Cell Reports. 36: 109720. PMID 34551296 DOI: 10.1016/j.celrep.2021.109720 |
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Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, ... ... Heneka MT, et al. A microRNA signature that correlates with cognition and is a target against cognitive decline. Embo Molecular Medicine. e13659. PMID 34633146 DOI: 10.15252/emmm.202013659 |
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Bendella Z, Widmann CN, Layer JP, Layer YL, Haase R, Sauer M, Bieler L, Lehnen NC, Paech D, Heneka MT, Radbruch A, Schmeel FC. Brain Volume Changes after COVID-19 Compared to Healthy Controls by Artificial Intelligence-Based MRI Volumetry. Diagnostics (Basel, Switzerland). 13. PMID 37238200 DOI: 10.3390/diagnostics13101716 |
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de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Heneka MT, et al. Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 14: 716. PMID 36759603 DOI: 10.1038/s41467-023-36192-x |
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| 2004 |
Klotz L, Schmidt M, Sastre M, Klockgether T, Heneka M. Mechanismen antientzündlicher und antiproliferativer Effekte von PPARgamma-Agonisten und ihre Bedeutung für die Therapie der Multiplen Sklerose Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-832965 |
0.168 |
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| 2018 |
Traschütz A, Heneka MT. Screening for Niemann-Pick Type C Disease in a Memory Clinic Cohort. Jimd Reports. 44: 109-114. PMID 30187371 DOI: 10.1007/8904_2018_133 |
0.168 |
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| 2021 |
Manabe T, Rácz I, Schwartz S, Oberle L, Santarelli F, Emmrich JV, Neher JJ, Heneka MT. Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. Journal of Neurochemistry. PMID 34379806 DOI: 10.1111/jnc.15491 |
0.165 |
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| 2021 |
Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, Terrando N, Willette AA, Willette SA. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34874605 DOI: 10.1002/alz.12488 |
0.162 |
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| 2023 |
Ersoezlue E, Perneczky R, Tato M, Utecht J, Kurz C, Häckert J, Guersel S, Burow L, Koller G, Stoecklein S, Keeser D, Papazov B, Totzke M, Ballarini T, Brosseron F, ... ... Heneka MT, et al. A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum. Journal of Alzheimer's Disease : Jad. PMID 36806502 DOI: 10.3233/JAD-220464 |
0.156 |
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| 2007 |
Rueger MA, Kracht LW, Hilker R, Thiel A, Sobesky J, Winkeler A, Thomas AV, Heneka MT, Graf R, Herholz K, Heiss WD, Jacobs AH. Role of in vivo imaging of the central nervous system for developing novel drugs. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology. 51: 164-81. PMID 17420717 |
0.153 |
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| 2021 |
Janssen O, Jansen WJ, Vos SJB, Boada M, Parnetti L, Gabryelewicz T, Fladby T, Molinuevo JL, Villeneuve S, Hort J, Epelbaum S, Lleó A, Engelborghs S, van der Flier WM, Landau S, ... ... Heneka M, et al. Characteristics of subjective cognitive decline associated with amyloid positivity. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34877782 DOI: 10.1002/alz.12512 |
0.152 |
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| 2021 |
Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, ... ... Heneka MT, et al. mTOR-dependent translation amplifies microglia priming in aging mice. The Journal of Clinical Investigation. 131. PMID 34651589 DOI: 10.1172/JCI155208 |
0.151 |
|
| 1998 |
Heneka MT, Löschmann PA, Gleichmann M, Weller M, Schulz JB, Wüllner U, Klockgether T. Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide. Journal of Neurochemistry. 71: 88-94. PMID 9648854 DOI: 10.1046/j.1471-4159.1998.71010088.x |
0.15 |
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| 2021 |
Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell. PMID 34555357 DOI: 10.1016/j.cell.2021.09.007 |
0.15 |
|
| 2008 |
Heneka M. PPAR-gamma: bridging AD and type 2 diabetes? Aktuelle Neurologie. 35. DOI: 10.1055/s-0028-1086496 |
0.144 |
|
| 1998 |
Schulz JB, Weller M, Matthews RT, Heneka MT, Groscurth P, Martinou JC, Lommatzsch J, von Coelln R, Wüllner U, Löschmann PA, Beal MF, Dichgans J, Klockgether T. Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. Cell Death and Differentiation. 5: 847-57. PMID 10203688 DOI: 10.1038/sj.cdd.4400420 |
0.135 |
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| 2006 |
Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Modulation of proteolytic processing by glycosphingolipids generates amyloid β-peptide Sphingolipid Biology. 319-328. DOI: 10.1007/4-431-34200-1_25 |
0.127 |
|
| 1997 |
Heneka MT, Löschmann PA, Osswald H. Polymerized hemoglobin restores cardiovascular and kidney function in endotoxin-induced shock in the rat. The Journal of Clinical Investigation. 99: 47-54. PMID 9011575 DOI: 10.1172/JCI119132 |
0.125 |
|
| 2022 |
Castro-Gomez S, Binder J, Schievelkamp AH, Heneka MT. CNS Superficial Siderosis Mimicking a Motor Neuron Disease. Brain Sciences. 12. PMID 36421882 DOI: 10.3390/brainsci12111558 |
0.125 |
|
| 2024 |
Castro-Gomez S, Heneka MT. Innate immune activation in neurodegenerative diseases. Immunity. 57: 790-814. PMID 38599171 DOI: 10.1016/j.immuni.2024.03.010 |
0.12 |
|
| 2024 |
Brown GC, Heneka MT. The endotoxin hypothesis of Alzheimer's disease. Molecular Neurodegeneration. 19: 30. PMID 38561809 DOI: 10.1186/s13024-024-00722-y |
0.12 |
|
| 2022 |
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Heneka MT, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020 |
0.119 |
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| 2021 |
Castro-Gomez S, Radermacher B, Tacik P, Mirandola SR, Heneka MT, Weydt P. Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis. Brain Communications. 3: fcab274. PMID 34993474 DOI: 10.1093/braincomms/fcab274 |
0.119 |
|
| 2005 |
Sastre M, Roßner S, Bogdanovic N, Rosen E, Dewachter I, Borghgraef P, Evert B, Dumitrescu-Ozimek L, Thal D, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka M. NSAIDs repress BACE1 gene promoter activity by activation of PPARgamma Aktuelle Neurologie. 32. DOI: 10.1055/S-2005-919211 |
0.113 |
|
| 2008 |
Graf J, Tatenhorst L, Kummer M, Terwel D, Heneka M. Combination of PPARgamma activation and temozolomide chemotherapy leads to antineoplastic effects in glioma cells Aktuelle Neurologie. 35. DOI: 10.1055/s-0028-1086671 |
0.112 |
|
| 2015 |
Kurzwelly D, Krüger S, Biskup S, Heneka MT. A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation. Brain : a Journal of Neurology. PMID 25681414 DOI: 10.1093/brain/awv014 |
0.108 |
|
| 2003 |
Baltrons MA, Pedraza CE, Heneka MT, Garcí A. Neuroinflammatory agents down-regulate soluble guanylyl cyclase in astroglial cells by nitric oxide-dependent and independent mechanisms Bmc News and Views. 3. DOI: 10.1186/2048-4623-3-s2-p0006 |
0.104 |
|
| 2008 |
Papi A, Bartolini G, Tatenhorst L, Kummer M, Terwel D, Heneka M. Peroxisome proliferator-activated receptor and retinoid X receptor ligands in combination are potent antitumoral agents in the glioblastoma treatment Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086677 |
0.104 |
|
| 2021 |
Fritze T, Doblhammer G, Widmann CN, Heneka MT. Time course of dementia following sepsis in German health claims data. Neurology(R) Neuroimmunology & Neuroinflammation. 8. PMID 33293458 DOI: 10.1212/NXI.0000000000000911 |
0.103 |
|
| 2023 |
Ising C, Heneka MT. Chronic inflammation: a potential target in tauopathies. The Lancet. Neurology. 22: 371-373. PMID 37059499 DOI: 10.1016/S1474-4422(23)00116-3 |
0.1 |
|
| 2005 |
Rueger MA, Winkeler A, Miletic H, Kaestle C, Richter R, Schneider G, Hilker R, Heneka MT, Ernestus RI, Hampl JA, Fraefel C, Jacobs AH. Variability in infectivity of primary cell cultures of human brain tumors with HSV-1 amplicon vectors. Gene Therapy. 12: 588-96. PMID 15674397 DOI: 10.1038/sj.gt.3302462 |
0.095 |
|
| 2022 |
Berron D, Ziegler G, Vieweg P, Billette O, Güsten J, Grande X, Heneka MT, Schneider A, Teipel S, Jessen F, Wagner M, Düzel E. Feasibility of Digital Memory Assessments in an Unsupervised and Remote Study Setting. Frontiers in Digital Health. 4: 892997. PMID 35721797 DOI: 10.3389/fdgth.2022.892997 |
0.095 |
|
| 2008 |
Tatenhorst L, Graf J, Kummer M, Terwel D, Heneka M. Additive antineoplastic effects of PPARgamma activation and radiation on glioma cells Aktuelle Neurologie. 35. DOI: 10.1055/s-0028-1086550 |
0.088 |
|
| 2021 |
Widmann CN, Wieberneit M, Bieler L, Bernsen S, Gräfenkämper R, Brosseron F, Schmeel C, Tacik P, Skowasch D, Radbruch A, Heneka MT. Longitudinal Neurocognitive and Pulmonological Profile of Long COVID-19: Protocol for the COVIMMUNE-Clin Study. Jmir Research Protocols. 10: e30259. PMID 34559059 DOI: 10.2196/30259 |
0.088 |
|
| 1997 |
Heneka MT, Ruetten H, Millar C, Thiemermann C, Vane JR. EFFECTS OF IBUPROFEN ON INDUCIBLE NITRIC OXIDE SYNTHASE, HAEMODYNAMICS AND ORGAN DYSFUNCTION IN A RAT MODEL OF SEPTIC SHOCK Shock. 7: 166. DOI: 10.1097/00024382-199703001-00676 |
0.085 |
|
| 2021 |
Aretz B, Janssen F, Vonk JM, Heneka MT, Boezen HM, Doblhammer G. Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes. Environmental Research. 201: 111533. PMID 34153335 DOI: 10.1016/j.envres.2021.111533 |
0.085 |
|
| 2021 |
Aretz B, Janssen F, Vonk JM, Heneka MT, Boezen HM, Doblhammer G. Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes. Environmental Research. 201: 111533. PMID 34153335 DOI: 10.1016/j.envres.2021.111533 |
0.085 |
|
| 2023 |
Rakuša E, Fink A, Tamgüney G, Heneka MT, Doblhammer G. Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case-Control Study Based on German Health Claims Data. Journal of Alzheimer's Disease : Jad. PMID 37182873 DOI: 10.3233/JAD-221153 |
0.084 |
|
| 2011 |
Gaikwad SM, Widmann CN, Heneka MT. Sepsis–induced neuronal dysfunction and death Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. 200-207. DOI: 10.1017/CBO9781139248822.024 |
0.074 |
|
| 2024 |
Schuster J, Dreyhaupt J, Mönkemöller K, Dupuis L, Dieterlé S, Weishaupt JH, Kassubek J, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, ... ... Heneka MT, et al. In-depth analysis of data from the RAS-ALS study reveals new insights in rasagiline treatment for amyotrophic lateral sclerosis. European Journal of Neurology. e16204. PMID 38240416 DOI: 10.1111/ene.16204 |
0.063 |
|
| 1997 |
Heneka MT, Löschmann P, Osswald H. Beneficial Effects Of Polymerized Hemoglobin On Cardiovascular And Renal Function By Scavenging Nitric Oxide In Septic Shock Shock. 7: 146. DOI: 10.1097/00024382-199703001-00592 |
0.056 |
|
| 2020 |
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, et al. Author Correction: A guiding map for inflammation. Nature Immunology. PMID 33288963 DOI: 10.1038/s41590-020-00846-5 |
0.046 |
|
| 2022 |
Krieger J, Frackowiak M, Berger M, Heneka MT, Jacobs AH. Falls at advanced age - The importance to search for benign paroxysmal positional vertigo (BPPV). Experimental Gerontology. 165: 111868. PMID 35700849 DOI: 10.1016/j.exger.2022.111868 |
0.04 |
|
| 2015 |
Rosengarten B, Heneka MT, Axer H. Current aspects of sepsis therapy on neurointensive care units: part 2: Sepsis-related encephalopathy | Aktuelle Therapie der Sepsis auf der neurologischen Intensivstation: Teil 2: Septische Enzephalopathie Aktuelle Neurologie. 42: 148-155. DOI: 10.1055/s-0034-1387632 |
0.028 |
|
| 2013 |
Heneka M. Im Kampf gegen das Vergessen Forschung. 38: 17-21. DOI: 10.1002/fors.201390021 |
0.01 |
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