Baruch Frenkel - Publications

Affiliations: 
Biochemistry and Molecular Biology: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sabag E, Halperin E, Liron T, Hiram-Bab S, Frenkel B, Gabet Y. Hormone-independent sexual dimorphism in the regulation of bone resorption by Krox20. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31398266 DOI: 10.1002/Jbmr.3847  0.439
2018 Luo J, Chimge NO, Zhou B, Flodby P, Castaldi A, Firth AL, Liu Y, Wang H, Yang C, Marconett CN, Crandall ED, Offringa IA, Frenkel B, Borok Z. CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro. International Journal of Cancer. PMID 30325015 DOI: 10.1002/Ijc.31734  0.424
2018 Amzaleg Y, Ji J, Kittivanichkul D, E Törnqvist A, Windahl S, Sabag E, Khalid AB, Sternberg H, West M, Katzenellenbogen JA, Krum SA, Chimge NO, Schones DE, Gabet Y, Ohlsson C, ... Frenkel B, et al. Estrogens and selective estrogen receptor modulators differentially antagonize Runx2 in ST2 mesenchymal progenitor cells. The Journal of Steroid Biochemistry and Molecular Biology. PMID 29751107 DOI: 10.1016/J.Jsbmb.2018.05.002  0.46
2017 Martin A, Yu J, Xiong J, Khalid AB, Katzenellenbogen B, Kim SH, Katzenellenbogen JA, Malaivijitnond S, Gabet Y, Krum SA, Frenkel B. Estrogens and Androgens Inhibit Association of RANKL with the Pre-osteoblast Membrane through Post-translational Mechanisms. Journal of Cellular Physiology. PMID 28213978 DOI: 10.1002/Jcp.25862  0.368
2016 Vuong W, Tew BY, Little GH, Frenkel B, Jones JO. High-throughput screen for inhibitors of androgen receptor-RUNX2 transcriptional regulation in prostate cancer. The Journal of Pharmacology and Experimental Therapeutics. PMID 27554677 DOI: 10.1124/Jpet.116.234567  0.439
2016 Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon Y, Chimge NO, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, et al. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase. Molecular Cell. 62: 507-519. PMID 27203177 DOI: 10.1016/J.Molcel.2016.04.014  0.333
2016 Morimoto E, Li M, Khalid AB, Krum SA, Chimge NO, Frenkel B. Glucocorticoids Hijack Runx2 to Stimulate Wif1 for Suppression of Osteoblast Growth and Differentiation. Journal of Cellular Physiology. PMID 27061521 DOI: 10.1002/Jcp.25399  0.539
2016 Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, ... ... Frenkel B, et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer. Nature Communications. 7: 10751. PMID 26916619 DOI: 10.1038/Ncomms10751  0.36
2015 Frenkel B, White W, Tuckermann J. Glucocorticoid-Induced Osteoporosis. Advances in Experimental Medicine and Biology. 872: 179-215. PMID 26215995 DOI: 10.1007/978-1-4939-2895-8_8  0.496
2015 Martin A, Xiong J, Koromila T, Ji JS, Chang S, Song YS, Miller JL, Han CY, Kostenuik P, Krum SA, Chimge NO, Gabet Y, Frenkel B. Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association. Bone. 75: 96-104. PMID 25701138 DOI: 10.1016/J.Bone.2015.02.007  0.505
2015 HaDuong JH, Blavier L, Baniwal SK, Frenkel B, Malvar J, Punj V, Sposto R, DeClerck YA. Interaction between bone marrow stromal cells and neuroblastoma cells leads to a VEGFA-mediated osteoblastogenesis. International Journal of Cancer. Journal International Du Cancer. 137: 797-809. PMID 25648303 DOI: 10.1002/Ijc.29465  0.497
2015 Yu JL, Adisetiyo H, Little GH, Vangsness CT, Jiang J, Sternberg H, West MD, Frenkel B. Initial Characterization of Osteoblast Differentiation and Loss of RUNX2 Stability in the Newly Established SK11 Human Embryonic Stem Cell-Derived Cell Line. Journal of Cellular Physiology. 230: 237-41. PMID 25160731 DOI: 10.1002/Jcp.24773  0.454
2015 Vuong W, Tew B, Little G, Frenkel B, Jones J. Small-Molecule Inhibition of the Androgen Receptor (AR)-RUNX2 Interaction in Prostate Cancer (PC) The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.945.10  0.407
2014 Adisetiyo H, Liang M, Liao CP, Jeong JH, Cohen MB, Roy-Burman P, Frenkel B. Dependence of castration-resistant prostate cancer (CRPC) stem cells on CRPC-associated fibroblasts. Journal of Cellular Physiology. 229: 1170-6. PMID 24752784 DOI: 10.1002/Jcp.24546  0.36
2014 Little GH, Baniwal SK, Adisetiyo H, Groshen S, Chimge NO, Kim SY, Khalid O, Hawes D, Jones JO, Pinski J, Schones DE, Frenkel B. Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness. Cancer Research. 74: 2857-68. PMID 24648349 DOI: 10.1158/0008-5472.Can-13-2003  0.482
2014 Soung do Y, Kalinowski J, Baniwal SK, Jacome-Galarza CE, Frenkel B, Lorenzo J, Drissi H. Runx1-mediated regulation of osteoclast differentiation and function. Molecular Endocrinology (Baltimore, Md.). 28: 546-53. PMID 24606124 DOI: 10.1210/Me.2013-1305  0.405
2014 Koromila T, Baniwal SK, Song YS, Martin A, Xiong J, Frenkel B. Glucocorticoids antagonize RUNX2 during osteoblast differentiation in cultures of ST2 pluripotent mesenchymal cells. Journal of Cellular Biochemistry. 115: 27-33. PMID 23943595 DOI: 10.1002/Jcb.24646  0.568
2014 Baniwal SK, Chimge NO, Jordan VC, Tripathy D, Frenkel B. Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner. Plos One. 8: e62361. PMID 23755096 DOI: 10.1371/Journal.Pone.0062361  0.458
2013 Pham LK, Liang M, Adisetiyo HA, Liao CP, Cohen MB, Tahara SM, Frenkel B, Kasahara N, Roy-Burman P. Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. Endocrine-Related Cancer. 20: 861-74. PMID 24042462 DOI: 10.1530/Erc-13-0100  0.401
2013 Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, et al. Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 291-301. PMID 22972752 DOI: 10.1002/Jbmr.1754  0.352
2013 HaDuong JH, Blavier L, Baniwal SK, Frenkel B, DeClerck YA. Abstract 2601: Interaction between bone marrow mesenchymal stem cells and neuroblastoma cells leads to osteoblastogenesis and VEGFA expression. Cancer Research. 73: 2601-2601. DOI: 10.1158/1538-7445.Am2013-2601  0.433
2012 Yen HY, Gabet Y, Liu Y, Martin A, Wu NL, Pike MC, Frenkel B, Maxson R, Dubeau L. Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 802-11. PMID 22488153 DOI: 10.1038/Labinvest.2012.58  0.345
2012 Purcell DJ, Khalid O, Ou CY, Little GH, Frenkel B, Baniwal SK, Stallcup MR. Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription. Journal of Cellular Biochemistry. 113: 2406-14. PMID 22389001 DOI: 10.1002/Jcb.24114  0.409
2012 Ting MC, Liao CP, Yan C, Jia L, Groshen S, Frenkel B, Roy-Burman P, Coetzee GA, Maxson R. An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice. Disease Models & Mechanisms. 5: 366-74. PMID 22279083 DOI: 10.1242/Dmm.008458  0.39
2012 Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B. Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Research. 40: 3538-47. PMID 22187159 DOI: 10.1093/Nar/Gkr1219  0.507
2012 Chimge NO, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 901-11. PMID 22147940 DOI: 10.1158/1078-0432.Ccr-11-1530  0.441
2012 Baniwal SK, Shah PK, Shi Y, Haduong JH, DeClerck YA, Gabet Y, Frenkel B. Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells Osteoporosis International. 23: 1399-1413. PMID 21881969 DOI: 10.1007/S00198-011-1728-5  0.55
2012 Baniwal SK, Little GH, Chimge NO, Frenkel B. Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation. Journal of Cellular Physiology. 227: 2276-82. PMID 21809344 DOI: 10.1002/Jcp.22966  0.52
2012 Liu Y, Yen H, Gabet Y, Wu N, Pike MC, Frenkel B, Maxson R, Dubeau L. Abstract 3279: Potential beneficial effects of the BRCA1 mutation carrier state on bone strength Cancer Research. 72: 3279-3279. DOI: 10.1158/1538-7445.Am2012-3279  0.352
2012 Noushmehr H, Coetzee SG, Rhie SK, Yan C, Haiman CA, Berman BP, Frenkel B, Coetzee GA. Abstract 1646: Integrative analysis identifies functional prostate cancer risk SNPs in genomic regulatory regions defined as enhancers Cancer Research. 72: 1646-1646. DOI: 10.1158/1538-7445.Am2012-1646  0.334
2011 Chimge NO, Baniwal SK, Little GH, Chen YB, Kahn M, Tripathy D, Borok Z, Frenkel B. Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. Breast Cancer Research : Bcr. 13: R127. PMID 22151997 DOI: 10.1186/Bcr3073  0.322
2011 Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA. Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Molecular and Cellular Biology. 31: 4648-62. PMID 21969603 DOI: 10.1128/Mcb.05934-11  0.468
2011 Börjesson AE, Windahl SH, Lagerquist MK, Engdahl C, Frenkel B, Movérare-Skrtic S, Sjögren K, Kindblom JM, Stubelius A, Islander U, Antal MC, Krust A, Chambon P, Ohlsson C. Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in bone. Proceedings of the National Academy of Sciences of the United States of America. 108: 6288-93. PMID 21444817 DOI: 10.1073/Pnas.1100454108  0.398
2011 Gabet Y, Noh T, Lee C, Frenkel B. Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin A transcription in primary osteoblast cultures. Journal of Cellular Physiology. 226: 991-8. PMID 20857405 DOI: 10.1002/Jcp.22412  0.813
2011 Ofek O, Attar-Namdar M, Kram V, Dvir-Ginzberg M, Mechoulam R, Zimmer A, Frenkel B, Shohami E, Bab I. CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 308-16. PMID 20803555 DOI: 10.1002/Jbmr.228  0.48
2010 Baniwal SK, Khalid O, Gabet Y, Shah RR, Purcell DJ, Mav D, Kohn-Gabet AE, Shi Y, Coetzee GA, Frenkel B. Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis. Molecular Cancer. 9: 258. PMID 20863401 DOI: 10.1186/1476-4598-9-258  0.571
2010 Gabet Y, Baniwal SK, Leclerc N, Shi Y, Kohn-Gabet AE, Cogan J, Dixon A, Bachar M, Guo L, Turman JE, Frenkel B. Krox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone mass. Blood. 116: 3964-71. PMID 20716776 DOI: 10.1182/Blood-2010-01-263830  0.502
2010 Berman BP, Frenkel B, Coetzee GA, Jia L. Androgen receptor responsive enhancers are flanked by consistently-positioned H3-acetylated nucleosomes. Cell Cycle (Georgetown, Tex.). 9: 2249-50. PMID 20495358 DOI: 10.4161/Cc.9.11.11621  0.49
2010 Frenkel B, Hong A, Baniwal SK, Coetzee GA, Ohlsson C, Khalid O, Gabet Y. Regulation of adult bone turnover by sex steroids. Journal of Cellular Physiology. 224: 305-10. PMID 20432458 DOI: 10.1002/Jcp.22159  0.41
2010 Coetzee GA, Jia L, Frenkel B, Henderson BE, Tanay A, Haiman CA, Freedman ML. A systematic approach to understand the functional consequences of non-protein coding risk regions. Cell Cycle (Georgetown, Tex.). 9: 256-9. PMID 20023379 DOI: 10.4161/Cc.9.2.10419  0.316
2009 Jia L, Landan G, Pomerantz M, Jaschek R, Herman P, Reich D, Yan C, Khalid O, Kantoff P, Oh W, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, et al. Functional enhancers at the gene-poor 8q24 cancer-linked locus. Plos Genetics. 5: e1000597. PMID 19680443 DOI: 10.1371/Journal.Pgen.1000597  0.4
2009 Warotayanont R, Frenkel B, Snead ML, Zhou Y. Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway. Biochemical and Biophysical Research Communications. 387: 558-63. PMID 19615979 DOI: 10.1016/J.Bbrc.2009.07.058  0.398
2009 Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao K, Kehoe SM, Lenz HJ, Haiman CA, Yan C, ... ... Frenkel B, et al. The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nature Genetics. 41: 882-4. PMID 19561607 DOI: 10.1038/Ng.403  0.305
2009 Noh T, Gabet Y, Cogan J, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee C, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett J, Müller R, ... ... Frenkel B, et al. Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner. Plos One. 4: e5438. PMID 19412553 DOI: 10.1371/Journal.Pone.0005438  0.79
2009 Baniwal SK, Khalid O, Sir D, Buchanan G, Coetzee GA, Frenkel B. Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA. Molecular Endocrinology (Baltimore, Md.). 23: 1203-14. PMID 19389811 DOI: 10.1210/Me.2008-0470  0.509
2009 Jariwala U, Cogan JP, Jia L, Frenkel B, Coetzee GA. Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions. The Prostate. 69: 392-400. PMID 19058140 DOI: 10.1002/Pros.20893  0.808
2009 Jia L, Khalid O, Frenkel B, Coetzee GA. Chromatin remodeling and androgen receptor-mediated transcription Androgen Action in Prostate Cancer. 405-424. DOI: 10.1007/978-0-387-69179-4_18  0.31
2008 Luppen CA, Chandler RL, Noh T, Mortlock DP, Frenkel B. BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization. Growth Factors (Chur, Switzerland). 26: 226-37. PMID 19021035 DOI: 10.1080/08977190802277880  0.793
2008 Jia L, Berman BP, Jariwala U, Yan X, Cogan JP, Walters A, Chen T, Buchanan G, Frenkel B, Coetzee GA. Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity. Plos One. 3: e3645. PMID 18997859 DOI: 10.1371/Journal.Pone.0003645  0.815
2008 Pregizer S, Baniwal SK, Yan X, Borok Z, Frenkel B. Progressive recruitment of Runx2 to genomic targets despite decreasing expression during osteoblast differentiation. Journal of Cellular Biochemistry. 105: 965-70. PMID 18821584 DOI: 10.1002/Jcb.21900  0.811
2008 Zhou B, Francis TA, Yang H, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z. GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1. American Journal of Physiology. Cell Physiology. 295: C1141-50. PMID 18768929 DOI: 10.1152/Ajpcell.00120.2008  0.415
2008 Khalid O, Baniwal SK, Purcell DJ, Leclerc N, Gabet Y, Stallcup MR, Coetzee GA, Frenkel B. Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer. Endocrinology. 149: 5984-95. PMID 18755791 DOI: 10.1210/En.2008-0680  0.402
2008 Barski A, Pregizer S, Frenkel B. Identification of transcription factor target genes by ChIP display. Methods in Molecular Biology (Clifton, N.J.). 455: 177-90. PMID 18463820 DOI: 10.1007/978-1-59745-104-8_14  0.792
2008 Zhou B, Zhong Q, Minoo P, Li C, Ann DK, Frenkel B, Morrisey EE, Crandall ED, Borok Z. Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain. American Journal of Respiratory Cell and Molecular Biology. 38: 750-8. PMID 18239190 DOI: 10.1165/Rcmb.2007-0350Oc  0.39
2008 Yang S, Pham LK, Liao CP, Frenkel B, Reddi AH, Roy-Burman P. A novel bone morphogenetic protein signaling in heterotypic cell interactions in prostate cancer. Cancer Research. 68: 198-205. PMID 18172312 DOI: 10.1158/0008-5472.Can-07-5074  0.509
2008 Leclerc N, Noh T, Cogan J, Samarawickrama DB, Smith E, Frenkel B. Opposing effects of glucocorticoids and Wnt signaling on Krox20 and mineral deposition in osteoblast cultures. Journal of Cellular Biochemistry. 103: 1938-51. PMID 17973254 DOI: 10.1002/Jcb.21587  0.823
2008 Gabet Y, Noh T, Cogan J, Tank A, Sasaki T, Criswell B, Dixon A, Tam J, Kohler T, Regev E, Kockeritz L, Woodgett J, Müller R, Chai Y, Smith E, ... ... Frenkel B, et al. Gender-specific control of peak bone mass by the Wnt pathway: Androgen signaling protects against lef1 haploinsufficiency-induced bone loss Bone. 42: S50. DOI: 10.1016/J.Bone.2007.12.085  0.785
2007 Prescott J, Jariwala U, Jia L, Cogan JP, Barski A, Pregizer S, Shen HC, Arasheben A, Neilson JJ, Frenkel B, Coetzee GA. Androgen receptor-mediated repression of novel target genes. The Prostate. 67: 1371-83. PMID 17624924 DOI: 10.1002/Pros.20623  0.783
2007 Jariwala U, Prescott J, Jia L, Barski A, Pregizer S, Cogan JP, Arasheben A, Tilley WD, Scher HI, Gerald WL, Buchanan G, Coetzee GA, Frenkel B. Identification of novel androgen receptor target genes in prostate cancer. Molecular Cancer. 6: 39. PMID 17553165 DOI: 10.1186/1476-4598-6-39  0.77
2007 Pregizer S, Barski A, Gersbach CA, García AJ, Frenkel B. Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2. Journal of Cellular Biochemistry. 102: 1458-71. PMID 17486635 DOI: 10.1002/Jcb.21366  0.836
2007 Zhu W, Boachie-Adjei O, Rawlins BA, Frenkel B, Boskey AL, Ivashkiv LB, Blobel CP. A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells. The Journal of Biological Chemistry. 282: 18676-85. PMID 17439946 DOI: 10.1074/Jbc.M610232200  0.495
2006 Ofek O, Karsak M, Leclerc N, Fogel M, Frenkel B, Wright K, Tam J, Attar-Namdar M, Kram V, Shohami E, Mechoulam R, Zimmer A, Bab I. Peripheral cannabinoid receptor, CB2, regulates bone mass. Proceedings of the National Academy of Sciences of the United States of America. 103: 696-701. PMID 16407142 DOI: 10.1073/Pnas.0504187103  0.485
2005 Miguel SM, Namdar-Attar M, Noh T, Frenkel B, Bab I. ERK1/2-activated de novo Mapkapk2 synthesis is essential for osteogenic growth peptide mitogenic signaling in osteoblastic cells. The Journal of Biological Chemistry. 280: 37495-502. PMID 16150701 DOI: 10.1074/Jbc.M503861200  0.8
2005 Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Research. 65: 5769-77. PMID 15994952 DOI: 10.1158/0008-5472.Can-05-0289  0.455
2005 Leclerc N, Noh T, Khokhar A, Smith E, Frenkel B. Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer. Arthritis and Rheumatism. 52: 929-39. PMID 15751078 DOI: 10.1002/Art.20872  0.831
2005 Smith E, Meyerrose TE, Kohler T, Namdar-Attar M, Bab N, Lahat O, Noh T, Li J, Karaman MW, Hacia JG, Chen TT, Nolta JA, Müller R, Bab I, Frenkel B. Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivo. Nucleic Acids Research. 33: 1298-308. PMID 15741183 DOI: 10.1093/Nar/Gki248  0.782
2005 Smith E, Frenkel B. Glucocorticoids inhibit the transcriptional activity of LEF/TCF in differentiating osteoblasts in a glycogen synthase kinase-3beta-dependent and -independent manner. The Journal of Biological Chemistry. 280: 2388-94. PMID 15537647 DOI: 10.1074/Jbc.M406294200  0.445
2005 Meyerrose TE, Smith E, Nolta JA, Frenkel B. 1121. Osteogenic Growth Peptide Preferentially Enhances Trabecular Bone Mass Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.669  0.4
2004 Leclerc N, Luppen CA, Ho VV, Nagpal S, Hacia JG, Smith E, Frenkel B. Gene expression profiling of glucocorticoid-inhibited osteoblasts. Journal of Molecular Endocrinology. 33: 175-93. PMID 15291752 DOI: 10.1677/Jme.0.0330175  0.834
2004 Barski A, Frenkel B. ChIP Display: novel method for identification of genomic targets of transcription factors. Nucleic Acids Research. 32: e104. PMID 15252151 DOI: 10.1093/Nar/Gnh097  0.654
2003 Zalavras C, Shah S, Birnbaum MJ, Frenkel B. Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosis. Critical Reviews in Eukaryotic Gene Expression. 13: 221-35. PMID 14696969 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I24.140  0.418
2003 Luppen CA, Leclerc N, Noh T, Barski A, Khokhar A, Boskey AL, Smith E, Frenkel B. Brief bone morphogenetic protein 2 treatment of glucocorticoid-inhibited MC3T3-E1 osteoblasts rescues commitment-associated cell cycle and mineralization without alteration of Runx2. The Journal of Biological Chemistry. 278: 44995-5003. PMID 12933820 DOI: 10.1074/Jbc.M306730200  0.792
2003 Luppen CA, Smith E, Spevak L, Boskey AL, Frenkel B. Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1186-97. PMID 12854828 DOI: 10.1359/Jbmr.2003.18.7.1186  0.827
2002 Smith E, Coetzee GA, Frenkel B. Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3beta. The Journal of Biological Chemistry. 277: 18191-7. PMID 11877389 DOI: 10.1074/Jbc.M109708200  0.411
2000 Holtom PD, Pavkovic SA, Bravos PD, Patzakis MJ, Shepherd LE, Frenkel B. Inhibitory effects of the quinolone antibiotics trovafloxacin, ciprofloxacin, and levofloxacin on osteoblastic cells in vitro Journal of Orthopaedic Research. 18: 721-727. PMID 11117292 DOI: 10.1002/Jor.1100180507  0.364
2000 Smith E, Redman RA, Logg CR, Coetzee GA, Kasahara N, Frenkel B. Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes. The Journal of Biological Chemistry. 275: 19992-20001. PMID 10867026 DOI: 10.1074/Jbc.M001758200  0.381
1999 Hou Z, Nguyen Q, Frenkel B, Nilsson SK, Milne M, Van Wijnen AJ, Stein JL, Quesenberry P, Lian JB, Stein GS. Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy Proceedings of the National Academy of Sciences of the United States of America. 96: 7294-7299. PMID 10377408 DOI: 10.1073/Pnas.96.13.7294  0.49
1999 Bab I, Smith E, Gavish H, Attar-Namdar M, Chorev M, Chen YC, Muhlrad A, Birnbaum MJ, Stein G, Frenkel B. Biosynthesis of osteogenic growth peptide via alternative translational initiation at AUG85 of histone H4 mRNA Journal of Biological Chemistry. 274: 14474-14481. PMID 10318873 DOI: 10.1074/Jbc.274.20.14474  0.354
1999 Nilsson SK, Dooner MS, Weier HU, Frenkel B, Lian JB, Stein GS, Quesenberry PJ. Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice Journal of Experimental Medicine. 189: 729-734. PMID 9989988 DOI: 10.1084/Jem.189.4.729  0.398
1999 Montecino M, Frenkel B, Van Wijnen AJ, Lian JB, Stein GS, Stein JL. Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo Biochemistry. 38: 1338-1345. PMID 9930996 DOI: 10.1021/Bi982171A  0.488
1999 Aslam F, McCabe L, Frenkel B, Van Wijnen AJ, Stein GS, Lian JB, Stein JL. AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: Requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation Endocrinology. 140: 63-70. PMID 9886808 DOI: 10.1210/Endo.140.1.6429  0.384
1997 Ryoo HM, Hoffmann HM, Beumer T, Frenkel B, Towler DA, Stein GS, Stein JL, van Wijnen AJ, Lian JB. Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Molecular Endocrinology (Baltimore, Md.). 11: 1681-94. PMID 9328350 DOI: 10.1210/Mend.11.11.0011  0.572
1997 Smith E, Frenkel B, MacLachlan TK, Giordano A, Stein JL, Lian JB, Stein GS. Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells Journal of Cellular Biochemistry. 66: 141-152. PMID 9213216 DOI: 10.1002/(Sici)1097-4644(19970801)66:2<141::Aid-Jcb2>3.0.Co;2-Q  0.372
1997 Lian JB, Shalhoub V, Aslam F, Frenkel B, Green J, Hamrah M, Stein GS, Stein JL. Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: Dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression Endocrinology. 138: 2117-2127. PMID 9112412 DOI: 10.1210/Endo.138.5.5117  0.478
1997 Frenkel B, Capparelli C, Van Auken M, Baran D, Bryan J, Stein JL, Stein GS, Lian JB. Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: Effects of age and sex Endocrinology. 138: 2109-2116. PMID 9112411 DOI: 10.1210/Endo.138.5.5105  0.475
1997 Guo B, Aslam F, Van Wijnen AJ, Roberts SGE, Frenkel B, Green MR, Deluca H, Lian JB, Stein GS, Stein JL. YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 94: 121-126. PMID 8990171 DOI: 10.1073/Pnas.94.1.121  0.412
1996 Montecino M, Frenkel B, Lian J, Stein J, Stein G. Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone-derived cells Journal of Cellular Biochemistry. 63: 221-228. PMID 8913873 DOI: 10.1002/(SICI)1097-4644(19961101)63:2<221::AID-JCB9>3.0.CO;2-#  0.512
1996 Banerjee C, Stein JL, Van Wijnen AJ, Frenkel B, Lian JB, Stein GS. Transforming growth factor-β1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site Endocrinology. 137: 1991-2000. PMID 8612540 DOI: 10.1210/Endo.137.5.8612540  0.395
1996 Frenkel B, Montecino M, Green J, Aslam F, Desai R, Banerjee C, Stein JL, Lian JB, Stein GS. Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: Requirement of upstream sequences for control by the proximal regulatory domain Endocrinology. 137: 1080-1088. PMID 8603577 DOI: 10.1210/Endo.137.3.8603577  0.477
1995 Birnbaum MJ, Wright KL, van Wijnen AJ, Ramsey-Ewing AL, Bourke MT, Last TJ, Aziz F, Frenkel B, Rao BR, Aronin N. Functional role for Sp1 in the transcriptional amplification of a cell cycle regulated histone H4 gene. Biochemistry. 34: 7648-58. PMID 7779811 DOI: 10.1021/Bi00023A011  0.44
1995 Smith E, Frenkel B, Lian JB, Stein JL, Schlegel R, Giordano A. Expression of Cell Cycle Regulatory Factors in Differentiating Osteoblasts: Postproliferative Up-Regulation of Cyclins B and E Cancer Research. 55: 5019-5024. PMID 7585545  0.349
1994 Frenkel B, Montecino M, Stein JL, Lian JB, Stein GS. A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: Promoter and cell type requirements Proceedings of the National Academy of Sciences of the United States of America. 91: 10923-10927. PMID 7971985 DOI: 10.1073/Pnas.91.23.10923  0.481
Show low-probability matches.