Year |
Citation |
Score |
2020 |
Crocetti L, Giovannoni MP, Cantini N, Guerrini G, Vergelli C, Schepetkin IA, Khlebnikov AI, Quinn MT. Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors. Frontiers in Chemistry. 8: 795. PMID 33033716 DOI: 10.3389/Fchem.2020.00795 |
0.345 |
|
2020 |
Kirpotina LN, Schepetkin IA, Hammaker D, Kuhs A, Khlebnikov AI, Quinn MT. Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis. Frontiers in Pharmacology. 11: 1145. PMID 32792961 DOI: 10.3389/Fphar.2020.01145 |
0.33 |
|
2020 |
Crocetti L, Vergelli C, Guerrini G, Cantini N, Kirpotina LN, Schepetkin IA, Quinn MT, Parisio C, Di Cesare Mannelli L, Ghelardini C, Giovannoni MP. Novel formyl peptide receptors (FPRs) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis. Bioorganic Chemistry. 100: 103880. PMID 32388428 DOI: 10.1016/J.Bioorg.2020.103880 |
0.351 |
|
2020 |
Kibler E, Lavrinenko A, Kolesnik I, Stankevich K, Bolbasov E, Kudryavtseva V, Leonov A, Schepetkin I, Khlebnikov A, Quinn MT, Tverdokhlebov S. Electrosprayed poly(lactic-co-glycolic acid) particles as a promising drug delivery system for the novel JNK inhibitor IQ-1. European Polymer Journal. 127. PMID 32372769 DOI: 10.1016/J.Eurpolymj.2020.109598 |
0.327 |
|
2020 |
Siemsen DW, Kirpotina LN, Malachowa N, Schepetkin IA, Porter AR, Lei B, DeLeo FR, Quinn MT. Isolation of Neutrophils from Nonhuman Species. Methods in Molecular Biology (Clifton, N.J.). 2087: 43-59. PMID 31728982 DOI: 10.1007/978-1-0716-0154-9_4 |
0.309 |
|
2019 |
Stankevich KS, Schepetkin IA, Goreninskii SI, Lavrinenko AK, Bolbasov EN, Kovrizhina AR, Kirpotina LN, Filimonov VD, Khlebnikov AI, Tverdokhlebov SI, Quinn MT. Poly(ε-caprolactone) Scaffolds Doped with c-Jun N-terminal Kinase Inhibitors Modulate Phagocyte Activation. Acs Biomaterials Science & Engineering. 5: 5990-5999. PMID 33405721 DOI: 10.1021/Acsbiomaterials.9B01401 |
0.366 |
|
2019 |
Giovannoni MP, Crocetti L, Cantini N, Guerrini G, Vergelli C, Iacovone A, Teodori E, Schepetkin IA, Quinn MT, Ciattini S, Rossi P, Paoli P. New 3-unsubstituted isoxazolones as potent human neutrophil elastase inhibitors: Synthesis and molecular dynamic simulation. Drug Development Research. PMID 31800122 DOI: 10.1002/Ddr.21625 |
0.323 |
|
2019 |
Giovannoni MP, Cantini N, Crocetti L, Guerrini G, Iacovone A, Schepetkin IA, Vergelli C, Khlebnikov AI, Quinn MT. Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase. Drug Development Research. PMID 31002441 DOI: 10.1002/Ddr.21539 |
0.363 |
|
2018 |
Schepetkin IA, Khlebnikov AI, Potapov AS, Kovrizhina AR, Matveevskaya VV, Belyanin ML, Atochin DN, Zanoza SO, Gaidarzhy NM, Lyakhov SA, Kirpotina LN, Quinn MT. Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors. European Journal of Medicinal Chemistry. 161: 179-191. PMID 30347329 DOI: 10.1016/J.Ejmech.2018.10.023 |
0.389 |
|
2017 |
Schepetkin IA, Kirpotina LN, Mitchell PT, Kishkentaeva АS, Shaimerdenova ZR, Atazhanova GA, Adekenov SM, Quinn MT. The natural sesquiterpene lactones arglabin, grosheimin, agracin, parthenolide, and estafiatin inhibit T cell receptor (TCR) activation. Phytochemistry. 146: 36-46. PMID 29216473 DOI: 10.1016/J.Phytochem.2017.11.010 |
0.375 |
|
2017 |
Crocetti L, Bartolucci G, Cilibrizzi A, Giovannoni MP, Guerrini G, Iacovone A, Menicatti M, Schepetkin IA, Khlebnikov AI, Quinn MT, Vergelli C. Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors. Chemistry Central Journal. 11: 127. PMID 29214393 DOI: 10.1186/S13065-017-0358-1 |
0.314 |
|
2017 |
Stama ML, Ślusarczyk J, Lacivita E, Kirpotina LN, Schepetkin IA, Chamera K, Riganti C, Perrone R, Quinn MT, Basta-Kaim A, Leopoldo M. Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation. European Journal of Medicinal Chemistry. PMID 29102463 DOI: 10.1016/J.Ejmech.2017.09.023 |
0.37 |
|
2017 |
Stama ML, Lacivita E, Kirpotina LN, Niso M, Perrone R, Schepetkin IA, Quinn MT, Leopoldo M. Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on Ureidopropanamide Scaffold Have Potential to Protect Against Inflammation-associated Oxidative Stress. Chemmedchem. PMID 28922577 DOI: 10.1002/Cmdc.201700429 |
0.361 |
|
2017 |
Kirpotina LN, Schepetkin IA, Khlebnikov AI, Ruban OI, Ge Y, Ye RD, Kominsky DJ, Quinn MT. 4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-Formyl Peptide Receptor 1 (FPR1) Antagonists. Biochemical Pharmacology. PMID 28690139 DOI: 10.1016/J.Bcp.2017.07.004 |
0.383 |
|
2017 |
Vergelli C, Schepetkin IA, Crocetti L, Iacovone A, Giovannoni MP, Guerrini G, Khlebnikov AI, Ciattini S, Ciciani G, Quinn MT. Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 821-831. PMID 28612630 DOI: 10.1080/14756366.2017.1326915 |
0.36 |
|
2015 |
Giovannoni MP, Schepetkin IA, Crocetti L, Ciciani G, Cilibrizzi A, Guerrini G, Khlebnikov AI, Quinn MT, Vergelli C. Cinnoline derivatives as human neutrophil elastase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-12. PMID 26194018 DOI: 10.3109/14756366.2015.1057718 |
0.37 |
|
2015 |
Maeda DY, Peck AM, Schuler AD, Quinn MT, Kirpotina LN, Wicomb WN, Auten RL, Gundla R, Zebala JA. Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model. Bioorganic & Medicinal Chemistry Letters. 25: 2280-4. PMID 25933594 DOI: 10.1016/J.Bmcl.2015.04.041 |
0.336 |
|
2015 |
Schepetkin IA, Kirpotina LN, Hammaker D, Kochetkova I, Khlebnikov AI, Lyakhov SA, Firestein GS, Quinn MT. Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 353: 505-16. PMID 25784649 DOI: 10.1124/Jpet.114.220251 |
0.33 |
|
2015 |
Lacivita E, Schepetkin IA, Stama ML, Kirpotina LN, Colabufo NA, Perrone R, Khlebnikov AI, Quinn MT, Leopoldo M. Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2. Bioorganic & Medicinal Chemistry. 23: 3913-24. PMID 25549897 DOI: 10.1016/J.Bmc.2014.12.007 |
0.32 |
|
2014 |
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Cheng N, Ye RD, Quinn MT. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochemical Pharmacology. 92: 627-41. PMID 25450672 DOI: 10.1016/J.Bcp.2014.09.027 |
0.397 |
|
2014 |
Maeda DY, Peck AM, Schuler AD, Quinn MT, Kirpotina LN, Wicomb WN, Fan GH, Zebala JA. Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2. Journal of Medicinal Chemistry. 57: 8378-97. PMID 25254640 DOI: 10.1021/Jm500827T |
0.347 |
|
2014 |
Siemsen DW, Malachowa N, Schepetkin IA, Whitney AR, Kirpotina LN, Lei B, Deleo FR, Quinn MT. Neutrophil isolation from nonhuman species. Methods in Molecular Biology (Clifton, N.J.). 1124: 19-37. PMID 24504944 DOI: 10.1007/978-1-62703-845-4_3 |
0.312 |
|
2014 |
Schepetkin IA, Khlebnikov AI, Giovannoni MP, Kirpotina LN, Cilibrizzi A, Quinn MT. Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition Current Medicinal Chemistry. 21: 1478-1504. PMID 24350845 DOI: 10.2174/0929867321666131218095521 |
0.328 |
|
2013 |
Crocetti L, Schepetkin IA, Cilibrizzi A, Graziano A, Vergelli C, Giomi D, Khlebnikov AI, Quinn MT, Giovannoni MP. Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. Journal of Medicinal Chemistry. 56: 6259-72. PMID 23844670 DOI: 10.1021/Jm400742J |
0.34 |
|
2013 |
Kouakou K, Schepetkin IA, Jun S, Kirpotina LN, Yapi A, Khramova DS, Pascual DW, Ovodov YS, Jutila MA, Quinn MT. Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis. Bmc Complementary and Alternative Medicine. 13: 149. PMID 23806004 DOI: 10.1186/1472-6882-13-149 |
0.362 |
|
2013 |
Giovannoni MP, Schepetkin IA, Cilibrizzi A, Crocetti L, Khlebnikov AI, Dahlgren C, Graziano A, Dal Piaz V, Kirpotina LN, Zerbinati S, Vergelli C, Quinn MT. Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. European Journal of Medicinal Chemistry. 64: 512-28. PMID 23685570 DOI: 10.1016/J.Ejmech.2013.03.066 |
0.366 |
|
2013 |
Schepetkin IA, Kouakou K, Yapi A, Kirpotina LN, Jutila MA, Quinn MT. Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum. International Immunopharmacology. 15: 628-37. PMID 23380150 DOI: 10.1016/J.Intimp.2013.01.015 |
0.349 |
|
2013 |
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Leopoldo M, Lucente E, Lacivita E, De Giorgio P, Quinn MT. 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2. Biochemical Pharmacology. 85: 404-16. PMID 23219934 DOI: 10.1016/J.Bcp.2012.11.015 |
0.343 |
|
2013 |
Crocetti L, Vergelli C, Cilibrizzi A, Graziano A, Khlebnikov AI, Kirpotina LN, Schepetkin IA, Quinn MT, Giovannoni MP. Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists Drug Development Research. 74: 259-271. DOI: 10.1002/Ddr.21076 |
0.375 |
|
2012 |
Lu T, Kobayashi SD, Quinn MT, Deleo FR. A NET Outcome. Frontiers in Immunology. 3: 365. PMID 23227026 DOI: 10.3389/Fimmu.2012.00365 |
0.32 |
|
2012 |
Ramstead AG, Schepetkin IA, Quinn MT, Jutila MA. Oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium, enhances IFNγ production by lymphocytes. Plos One. 7: e50546. PMID 23226309 DOI: 10.1371/Journal.Pone.0050546 |
0.33 |
|
2012 |
Cilibrizzi A, Schepetkin IA, Bartolucci G, Crocetti L, Dal Piaz V, Giovannoni MP, Graziano A, Kirpotina LN, Quinn MT, Vergelli C. Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. Bioorganic & Medicinal Chemistry. 20: 3781-92. PMID 22607879 DOI: 10.1016/J.Bmc.2012.04.043 |
0.359 |
|
2012 |
Graves SF, Kobayashi SD, Braughton KR, Whitney AR, Sturdevant DE, Rasmussen DL, Kirpotina LN, Quinn MT, DeLeo FR. Sublytic concentrations of Staphylococcus aureus Panton-Valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity. Journal of Leukocyte Biology. 92: 361-74. PMID 22581932 DOI: 10.1189/Jlb.1111575 |
0.347 |
|
2012 |
Liu M, Zhu H, Li J, Garcia CC, Feng W, Kirpotina LN, Hilmer J, Tavares LP, Layton AW, Quinn MT, Bothner B, Teixeira MM, Lei B. Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasion. Plos Pathogens. 8: e1002624. PMID 22496650 DOI: 10.1371/Journal.Ppat.1002624 |
0.319 |
|
2012 |
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Hanks TS, Kochetkova I, Pascual DW, Jutila MA, Quinn MT. Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors. Molecular Pharmacology. 81: 832-45. PMID 22434859 DOI: 10.1124/Mol.111.077446 |
0.379 |
|
2012 |
Khlebnikov AI, Schepetkin IA, Kirpotina LN, Brive L, Dahlgren C, Jutila MA, Quinn MT. Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1. Journal of Molecular Modeling. 18: 2831-43. PMID 22127612 DOI: 10.1007/S00894-011-1307-X |
0.319 |
|
2011 |
Crocetti L, Giovannoni MP, Schepetkin IA, Quinn MT, Khlebnikov AI, Cilibrizzi A, Piaz VD, Graziano A, Vergelli C. Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. Bioorganic & Medicinal Chemistry. 19: 4460-72. PMID 21741848 DOI: 10.1016/J.Bmc.2011.06.036 |
0.35 |
|
2011 |
Briones AM, Tabet F, Callera GE, Montezano AC, Yogi A, He Y, Quinn MT, Salaices M, Touyz RM. Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR. Journal of the American Society of Hypertension : Jash. 5: 137-53. PMID 21419746 DOI: 10.1016/J.Jash.2011.02.001 |
0.323 |
|
2011 |
Holderness J, Schepetkin IA, Freedman B, Kirpotina LN, Quinn MT, Hedges JF, Jutila MA. Polysaccharides isolated from Açaà fruit induce innate immune responses. Plos One. 6: e17301. PMID 21386979 DOI: 10.1371/Journal.Pone.0017301 |
0.339 |
|
2011 |
Yu P, Han W, Villar VA, Li H, Arnaldo FB, Concepcion GP, Felder RA, Quinn MT, Jose PA. Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk. Free Radical Biology & Medicine. 50: 832-40. PMID 21193028 DOI: 10.1016/J.Freeradbiomed.2010.12.027 |
0.345 |
|
2011 |
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Jutila MA, Quinn MT. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors. Molecular Pharmacology. 79: 77-90. PMID 20943772 DOI: 10.1124/Mol.110.068288 |
0.328 |
|
2010 |
Khlebnikov AI, Schepetkin IA, Quinn MT. Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors. European Journal of Medicinal Chemistry. 45: 5406-19. PMID 20870313 DOI: 10.1016/J.Ejmech.2010.09.001 |
0.313 |
|
2010 |
Montezano AC, Burger D, Paravicini TM, Chignalia AZ, Yusuf H, Almasri M, He Y, Callera GE, He G, Krause KH, Lambeth D, Quinn MT, Touyz RM. Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells. Circulation Research. 106: 1363-73. PMID 20339118 DOI: 10.1161/Circresaha.109.216036 |
0.306 |
|
2010 |
Kirpotina LN, Khlebnikov AI, Schepetkin IA, Ye RD, Rabiet MJ, Jutila MA, Quinn MT. Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition. Molecular Pharmacology. 77: 159-70. PMID 19903830 DOI: 10.1124/Mol.109.060673 |
0.349 |
|
2010 |
Maeda DY, Quinn MT, Schepetkin IA, Kirpotina LN, Zebala JA. Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism. The Journal of Pharmacology and Experimental Therapeutics. 332: 145-52. PMID 19779130 DOI: 10.1124/Jpet.109.159020 |
0.357 |
|
2009 |
Quinn MT, Schepetkin IA. Role of NADPH oxidase in formation and function of multinucleated giant cells. Journal of Innate Immunity. 1: 509-26. PMID 20375608 DOI: 10.1159/000228158 |
0.345 |
|
2009 |
Schepetkin IA, Kirpotina LN, Jakiw L, Khlebnikov AI, Blaskovich CL, Jutila MA, Quinn MT. Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium. Journal of Immunology (Baltimore, Md. : 1950). 183: 6754-66. PMID 19846877 DOI: 10.4049/Jimmunol.0901827 |
0.378 |
|
2009 |
Graff JC, Kimmel EM, Freedman B, Schepetkin IA, Holderness J, Quinn MT, Jutila MA, Hedges JF. Polysaccharides derived from Yamoa (Funtumia elastica) prime gammadelta T cells in vitro and enhance innate immune responses in vivo. International Immunopharmacology. 9: 1313-22. PMID 19671448 DOI: 10.1016/J.Intimp.2009.07.015 |
0.319 |
|
2009 |
Cilibrizzi A, Quinn MT, Kirpotina LN, Schepetkin IA, Holderness J, Ye RD, Rabiet MJ, Biancalani C, Cesari N, Graziano A, Vergelli C, Pieretti S, Dal Piaz V, Giovannoni MP. 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors. Journal of Medicinal Chemistry. 52: 5044-57. PMID 19639995 DOI: 10.1021/Jm900592H |
0.339 |
|
2009 |
Siemsen DW, Kirpotina LN, Jutila MA, Quinn MT. Inhibition of the human neutrophil NADPH oxidase by Coxiella burnetii. Microbes and Infection / Institut Pasteur. 11: 671-9. PMID 19379824 DOI: 10.1016/J.Micinf.2009.04.005 |
0.395 |
|
2009 |
Raad H, Paclet MH, Boussetta T, Kroviarski Y, Morel F, Quinn MT, Gougerot-Pocidalo MA, Dang PM, El-Benna J. Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1011-22. PMID 19028840 DOI: 10.1096/Fj.08-114553 |
0.34 |
|
2008 |
Khlebnikov AI, Schepetkin IA, Kirpotina LN, Quinn MT. Computational structure-activity relationship analysis of non-peptide inducers of macrophage tumor necrosis factor-alpha production. Bioorganic & Medicinal Chemistry. 16: 9302-12. PMID 18815052 DOI: 10.1016/J.Bmc.2008.08.078 |
0.322 |
|
2008 |
Schepetkin IA, Xie G, Kirpotina LN, Klein RA, Jutila MA, Quinn MT. Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha. International Immunopharmacology. 8: 1455-66. PMID 18597716 DOI: 10.1016/J.Intimp.2008.06.003 |
0.341 |
|
2008 |
Nemali S, Siemsen DW, Nelson LK, Bunger PL, Faulkner CL, Rainard P, Gauss KA, Jutila MA, Quinn MT. Molecular analysis of the bovine anaphylatoxin C5a receptor. Journal of Leukocyte Biology. 84: 537-49. PMID 18480166 DOI: 10.1189/Jlb.0208142 |
0.328 |
|
2008 |
Schepetkin IA, Kirpotina LN, Tian J, Khlebnikov AI, Ye RD, Quinn MT. Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production. Molecular Pharmacology. 74: 392-402. PMID 18458054 DOI: 10.1124/Mol.108.046946 |
0.347 |
|
2008 |
Xie G, Schepetkin IA, Siemsen DW, Kirpotina LN, Wiley JA, Quinn MT. Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita. Phytochemistry. 69: 1359-71. PMID 18325553 DOI: 10.1016/J.Phytochem.2008.01.009 |
0.354 |
|
2008 |
Khlebnikov AI, Schepetkin IA, Quinn MT. Structure-activity relationship analysis of N-benzoylpyrazoles for elastase inhibitory activity: a simplified approach using atom pair descriptors. Bioorganic & Medicinal Chemistry. 16: 2791-802. PMID 18234502 DOI: 10.1016/J.Bmc.2008.01.014 |
0.305 |
|
2008 |
Mofarrahi M, Brandes RP, Gorlach A, Hanze J, Terada LS, Quinn MT, Mayaki D, Petrof B, Hussain SN. Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase. Antioxidants & Redox Signaling. 10: 559-74. PMID 18092937 DOI: 10.1089/Ars.2007.1792 |
0.314 |
|
2007 |
Quinn MT, DeLeo FR, Bokoch GM. Neutrophil methods and protocols. Preface. Methods in Molecular Biology (Clifton, N.J.). 412: vii-viii. PMID 18453100 DOI: 10.1007/978-1-59745-467-4 |
0.384 |
|
2007 |
Xie G, Schepetkin IA, Quinn MT. Immunomodulatory activity of acidic polysaccharides isolated from Tanacetum vulgare L. International Immunopharmacology. 7: 1639-50. PMID 17996673 DOI: 10.1016/J.Intimp.2007.08.013 |
0.322 |
|
2007 |
Schepetkin IA, Khlebnikov AI, Quinn MT. N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase. Journal of Medicinal Chemistry. 50: 4928-38. PMID 17850059 DOI: 10.1021/Jm070600+ |
0.337 |
|
2007 |
Gauss KA, Nelson-Overton LK, Siemsen DW, Gao Y, DeLeo FR, Quinn MT. Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha. Journal of Leukocyte Biology. 82: 729-41. PMID 17537988 DOI: 10.1189/Jlb.1206735 |
0.334 |
|
2007 |
Ammons MC, Siemsen DW, Nelson-Overton LK, Quinn MT, Gauss KA. Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity. The Journal of Biological Chemistry. 282: 17941-52. PMID 17462995 DOI: 10.1074/Jbc.M610618200 |
0.31 |
|
2007 |
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Quinn MT. High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists. Molecular Pharmacology. 71: 1061-74. PMID 17229869 DOI: 10.1124/Mol.106.033100 |
0.367 |
|
2007 |
Khlebnikov AI, Schepetkin IA, Domina NG, Kirpotina LN, Quinn MT. Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems. Bioorganic & Medicinal Chemistry. 15: 1749-70. PMID 17166721 DOI: 10.1016/J.Bmc.2006.11.037 |
0.314 |
|
2006 |
Schepetkin IA, Khlebnikov AI, Kirpotina LN, Quinn MT. Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening. Journal of Medicinal Chemistry. 49: 5232-44. PMID 16913712 DOI: 10.1021/Jm0605132 |
0.315 |
|
2006 |
Marty C, Kozasa T, Quinn MT, Ye RD. Activation state-dependent interaction between Galphai and p67phox. Molecular and Cellular Biology. 26: 5190-200. PMID 16782902 DOI: 10.1128/Mcb.01979-05 |
0.314 |
|
2006 |
Quinn MT, Ammons MC, Deleo FR. The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction. Clinical Science (London, England : 1979). 111: 1-20. PMID 16764554 DOI: 10.1042/Cs20060059 |
0.326 |
|
2006 |
Yang Z, Asico LD, Yu P, Wang Z, Jones JE, Escano CS, Wang X, Quinn MT, Sibley DR, Romero GG, Felder RA, Jose PA. D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R96-R104. PMID 16352863 DOI: 10.1152/Ajpregu.00434.2005 |
0.303 |
|
2006 |
Khlebnikov AI, Schepetkin IA, Quinn MT. Quantitative structure-activity relationships for small non-peptide antagonists of CXCR2: indirect 3D approach using the frontal polygon method. Bioorganic & Medicinal Chemistry. 14: 352-65. PMID 16182534 DOI: 10.1016/J.Bmc.2005.08.026 |
0.322 |
|
2005 |
Schepetkin IA, Faulkner CL, Nelson-Overton LK, Wiley JA, Quinn MT. Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum. International Immunopharmacology. 5: 1783-99. PMID 16275615 DOI: 10.1016/J.Intimp.2005.05.009 |
0.333 |
|
2005 |
Ikeda S, Yamaoka-Tojo M, Hilenski L, Patrushev NA, Anwar GM, Quinn MT, Ushio-Fukai M. IQGAP1 regulates reactive oxygen species-dependent endothelial cell migration through interacting with Nox2. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2295-300. PMID 16179592 DOI: 10.1161/01.Atv.0000187472.55437.Af |
0.326 |
|
2005 |
Martyn KD, Kim MJ, Quinn MT, Dinauer MC, Knaus UG. p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils. Blood. 106: 3962-9. PMID 16099876 DOI: 10.1182/Blood-2005-03-0859 |
0.383 |
|
2005 |
Tejada-Simon MV, Serrano F, Villasana LE, Kanterewicz BI, Wu GY, Quinn MT, Klann E. Synaptic localization of a functional NADPH oxidase in the mouse hippocampus. Molecular and Cellular Neurosciences. 29: 97-106. PMID 15866050 DOI: 10.1016/J.Mcn.2005.01.007 |
0.313 |
|
2005 |
Touyz RM, Yao G, Quinn MT, Pagano PJ, Schiffrin EL. p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells role in NAD(P)H oxidase regulation by angiotensin II Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 512-518. PMID 15618548 DOI: 10.1161/01.Atv.0000154141.66879.98 |
0.334 |
|
2004 |
Hanna IR, Hilenski LL, Dikalova A, Taniyama Y, Dikalov S, Lyle A, Quinn MT, Lassègue B, Griendling KK. Functional association of nox1 with p22phox in vascular smooth muscle cells. Free Radical Biology & Medicine. 37: 1542-9. PMID 15477006 DOI: 10.1016/J.Freeradbiomed.2004.08.011 |
0.324 |
|
2003 |
Swain SD, Siemsen DW, Nelson LK, Sipes KM, Hanson AJ, Quinn MT. Inhibition of the neutrophil NADPH oxidase by adenosine is associated with increased movement of flavocytochrome b between subcellular fractions. Inflammation. 27: 45-58. PMID 12772776 DOI: 10.1023/A:1022639228723 |
0.358 |
|
2003 |
Brar SS, Kennedy TP, Quinn M, Hoidal JR. Redox signaling of NF-kappaB by membrane NAD(P)H oxidases in normal and malignant cells. Protoplasma. 221: 117-27. PMID 12768349 DOI: 10.1007/S00709-002-0059-Y |
0.329 |
|
2003 |
Brar SS, Corbin Z, Kennedy TP, Hemendinger R, Thornton L, Bommarius B, Arnold RS, Whorton AR, Sturrock AB, Huecksteadt TP, Quinn MT, Krenitsky K, Ardie KG, Lambeth JD, Hoidal JR. NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. American Journal of Physiology. Cell Physiology. 285: C353-69. PMID 12686516 DOI: 10.1152/Ajpcell.00525.2002 |
0.34 |
|
2003 |
Clements MK, Siemsen DW, Swain SD, Hanson AJ, Nelson-Overton LK, Rohn TT, Quinn MT. Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses. Journal of Leukocyte Biology. 73: 344-55. PMID 12629148 DOI: 10.1189/Jlb.0802401 |
0.335 |
|
2002 |
Kalinina N, Agrotis A, Tararak E, Antropova Y, Kanellakis P, Ilyinskaya O, Quinn MT, Smirnov V, Bobik A. Cytochrome b558-dependent NAD(P)H oxidase-phox units in smooth muscle and macrophages of atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 2037-43. PMID 12482831 DOI: 10.1161/01.Atv.0000040222.02255.0F |
0.32 |
|
2002 |
Gauss KA, Bunger PL, Siemsen DW, Young CJ, Nelson-Overton L, Prigge JR, Swain SD, Quinn MT. Molecular analysis of the bison phagocyte NADPH oxidase: cloning and sequencing of five NADPH oxidase cDNAs. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 133: 1-12. PMID 12223206 DOI: 10.1016/S1096-4959(02)00090-8 |
0.315 |
|
2002 |
Hanson AJ, Quinn MT. Effect of fibrin sealant composition on human neutrophil chemotaxis Journal of Biomedical Materials Research. 61: 474-481. PMID 12115473 DOI: 10.1002/Jbm.10196 |
0.303 |
|
2002 |
Brar SS, Kennedy TP, Sturrock AB, Huecksteadt TP, Quinn MT, Richard Whorton A, Hoidal JR. An NAD(P)H oxidase regulates growth and transcription in melanoma cells American Journal of Physiology - Cell Physiology. 282. PMID 11997235 DOI: 10.1152/Ajpcell.00496.2001 |
0.386 |
|
2002 |
Swain SD, Rohn TT, Quinn MT. Neutrophil priming in host defense: Role of oxidants as priming agents Antioxidants and Redox Signaling. 4: 69-83. PMID 11970845 DOI: 10.1089/152308602753625870 |
0.312 |
|
2002 |
Dang PM, Cross AR, Quinn MT, Babior BM. Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558 II. Proceedings of the National Academy of Sciences of the United States of America. 99: 4262-5. PMID 11917128 DOI: 10.1073/Pnas.072345299 |
0.313 |
|
2002 |
Brar SS, Kennedy TP, Sturrock AB, Huecksteadt TP, Quinn MT, Murphy TM, Chitano P, Hoidal JR. NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L782-95. PMID 11880305 DOI: 10.1152/Ajplung.00206.2001 |
0.328 |
|
2002 |
Borgquist JD, Quinn MT, Swain SD. Adhesion to extracellular matrix proteins modulates bovine neutrophil responses to inflammatory mediators. Journal of Leukocyte Biology. 71: 764-774. DOI: 10.1189/Jlb.71.5.764 |
0.325 |
|
2002 |
Gauss KA, Mascolo PL, Siemsen DW, Nelson LK, Bunger PL, Pagano PJ, Quinn MT. Cloning and sequencing of rabbit leukocyte NADPH oxidase genes reveals a unique p67phox homolog Journal of Leukocyte Biology. 71: 319-328. DOI: 10.1189/Jlb.71.2.319 |
0.31 |
|
2002 |
Gauss KA, Bunger PL, Quinn MT. AP-1 is essential for p67phox promoter activity Journal of Leukocyte Biology. 71: 163-172. DOI: 10.1189/Jlb.71.1.163 |
0.301 |
|
2001 |
Swain SD, Siemsen DW, Hanson AJ, Quinn MT. Activation-induced mobilization of secretory vesicles in bovine neutrophils American Journal of Veterinary Research. 62: 1776-1781. PMID 11703023 DOI: 10.2460/Ajvr.2001.62.1776 |
0.372 |
|
2001 |
Quinn MT, Swain SD, Parkos CA, Jutila KL, Siemsen DW, Kurk SL, Jesaitis AJ, Jutila MA. A carbohydrate neoepitope that is up-regulated on human mononuclear leucocytes by neuraminidase treatment or by cellular activation Immunology. 104: 185-197. PMID 11683959 DOI: 10.1046/J.1365-2567.2001.01300.X |
0.339 |
|
2000 |
Swain SD, Nelson LK, Hanson AJ, Siemsen DW, Quinn MT. Host defense function in neutrophils from the American bison (Bison bison). Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 127: 237-47. PMID 11064290 DOI: 10.1016/S1095-6433(00)00264-6 |
0.307 |
|
2000 |
Davis AR, Clements MK, Bunger PL, Siemsen DW, Quinn MT. Cloning and characterization of bovine low molecular weight GTPases (Rac1 and Rac2) and Rho GDP-dissociation Inhibitor 2 (D4-GDI) Veterinary Immunology and Immunopathology. 74: 285-301. PMID 10802295 DOI: 10.1016/S0165-2427(00)00176-8 |
0.364 |
|
2000 |
Bunger PL, Swain SD, Clements MK, Siemsen DW, Davis AR, Gauss KA, Quinn MT. Cloning and expression of bovine p47-phox and p67-phox: Comparison with the human and murine homologs Journal of Leukocyte Biology. 67: 63-72. PMID 10647999 DOI: 10.1002/Jlb.67.1.63 |
0.357 |
|
2000 |
Swain SD, Jutila KL, Quinn MT. Cell-surface lactoferrin as a marker for degranulation of specific granules in bovine neutrophils American Journal of Veterinary Research. 61: 29-37. PMID 10630774 DOI: 10.2460/Ajvr.2000.61.29 |
0.303 |
|
1999 |
Soltys J, Swain SD, Sipes KM, Nelson LK, Hanson AJ, Kantele JM, Jutila MA, Quinn MT. Isolation of bovine neutrophils with biomagnetic beads: comparison with standard Percoll density gradient isolation methods. Journal of Immunological Methods. 226: 71-84. PMID 10410973 DOI: 10.1016/S0022-1759(99)00045-9 |
0.305 |
|
1999 |
Rohn TT, Nelson LK, Davis AR, Quinn MT. Inhibition of GTP binding to Rac2 by peroxynitrite: potential role for tyrosine modification. Free Radical Biology & Medicine. 26: 1321-31. PMID 10381206 DOI: 10.1016/S0891-5849(98)00332-3 |
0.342 |
|
1999 |
Wang HD, Hope S, Du Y, Quinn MT, Cayatte A, Pagano PJ, Cohen RA. Paracrine Role of Adventitial Superoxide Anion in Mediating Spontaneous Tone of the Isolated Rat Aorta in Angiotensin II-Induced Hypertension Hypertension. 33: 1225-1232. PMID 10334816 DOI: 10.1161/01.Hyp.33.5.1225 |
0.309 |
|
1999 |
Rohn TT, Nelson LK, Sipes KM, Swain SD, Jutila KL, Quinn MT. Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response. Journal of Leukocyte Biology. 65: 59-70. PMID 9886247 DOI: 10.1002/Jlb.65.1.59 |
0.378 |
|
1998 |
Swain SD, Bunger PL, Sipes KM, Nelson LK, Jutila KL, Boylan SM, Quinn MT. Platelet-activating factor induces a concentration-dependent spectrum of functional responses in bovine neutrophils. Journal of Leukocyte Biology. 64: 817-27. PMID 9850166 DOI: 10.1002/Jlb.64.6.817 |
0.326 |
|
1998 |
Rohn TT, Nelson LK, Waeg G, Quinn MT. U-101033E (2,4-diaminopyrrolopyrimidine), a potent inhibitor of membrane lipid peroxidation as assessed by the production of 4-hydroxynonenal, malondialdehyde, and 4-hydroxynonenal--protein adducts. Biochemical Pharmacology. 56: 1371-9. PMID 9825737 DOI: 10.1016/S0006-2952(98)00266-4 |
0.302 |
|
1998 |
Burritt JB, Busse SC, Gizachew D, Siemsen DW, Quinn MT, Bond CW, Dratz EA, Jesaitis AJ. Antibody imprint of a membrane protein surface: Phagocyte flavocytochrome b Journal of Biological Chemistry. 273: 24847-24852. PMID 9733789 DOI: 10.1074/Jbc.273.38.24847 |
0.304 |
|
1998 |
Rohn TT, Quinn MT. Inhibition of peroxynitrite-mediated tyrosine nitration by a novel pyrrolopyrimidine antioxidant European Journal of Pharmacology. 353: 329-336. PMID 9726663 DOI: 10.1016/S0014-2999(98)00399-9 |
0.325 |
|
1998 |
Davis AR, Mascolo PL, Bunger PL, Sipes KM, Quinn MT. Cloning and sequencing of the bovine flavocytochrome b subunit proteins, gp91-phox and p22-phox: comparison with other known flavocytochrome b sequences Journal of Leukocyte Biology. 64: 114-123. PMID 9665285 DOI: 10.1002/Jlb.64.1.114 |
0.353 |
|
1998 |
Yu L, Quinn MT, Cross AR, Dinauer MC. Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 95: 7993-8. PMID 9653128 DOI: 10.1073/Pnas.95.14.7993 |
0.335 |
|
1998 |
Sankarapandi S, Zweier JL, Mukherjee G, Quinn MT, Huso DL. Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway. Archives of Biochemistry and Biophysics. 353: 312-21. PMID 9606965 DOI: 10.1006/Abbi.1998.0658 |
0.368 |
|
1997 |
Swain SD, Helgerson SL, Davis AR, Nelson LK, Quinn MT. Analysis of activation-induced conformational changes in p47phox using tryptophan fluorescence spectroscopy. The Journal of Biological Chemistry. 272: 29502-10. PMID 9368011 DOI: 10.1074/Jbc.272.47.29502 |
0.338 |
|
1997 |
Adams ER, Dratz EA, Gizachew D, Deleo FR, Yu L, Volpp BD, Vlases M, Jesaitis AJ, Quinn MT. Interaction of human neutrophil flavocytochrome b with cytosolic proteins: transferred-NOESY NMR studies of a gp91phox C-terminal peptide bound to p47phox. The Biochemical Journal. 325: 249-57. PMID 9224653 DOI: 10.1042/Bj3250249 |
0.314 |
|
1996 |
DeLeo FR, Jutila MA, Quinn MT. Characterization of peptide diffusion into electropermeabilized neutrophils. Journal of Immunological Methods. 198: 35-49. PMID 8914595 DOI: 10.1016/0022-1759(96)00144-5 |
0.362 |
|
1996 |
De Leo FR, Ulman KV, Davis AR, Jutila KL, Quinn MT. Assembly of the human neutrophil NADPH oxidase involves binding of p67(phox) and flavocytochrome b to a common functional domain in p47(phox) Journal of Biological Chemistry. 271: 17013-17020. PMID 8663333 DOI: 10.1074/Jbc.271.29.17013 |
0.336 |
|
1995 |
Quinn MT, Parkos CA, Jesaitis AJ. Purification of human neutrophil NADPH oxidase cytochrome b-558 and association with Rap1A Methods in Enzymology. 255: 476-487. PMID 8524135 DOI: 10.1016/S0076-6879(95)55050-X |
0.32 |
|
1995 |
Quinn MT, Linner JG, Siemsen D, Dratz EA, Buescher ES, Jesaitis AJ. Immunocytochemical detection of lipid peroxidation in phagosomes of human neutrophils: Correlation with expression of flavocytochrome b Journal of Leukocyte Biology. 57: 415-421. PMID 7884312 DOI: 10.1002/Jlb.57.3.415 |
0.343 |
|
1995 |
DeLeo FR, Yu L, Burritt JB, Loetterle LR, Bond CW, Jesaitis AJ, Quinn MT. Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries. Proceedings of the National Academy of Sciences of the United States of America. 92: 7110-4. PMID 7624379 DOI: 10.1073/Pnas.92.15.7110 |
0.322 |
|
1995 |
Burritt JB, Quinn MT, Jutila MA, Bond CW, Jesaitis AJ. Topological mapping of neutrophil cytochrome b epitopes with phage- display libraries Journal of Biological Chemistry. 270: 16974-16980. PMID 7622517 DOI: 10.1074/Jbc.270.28.16974 |
0.318 |
|
1995 |
Dorseuil O, Quinn MT, Bokoch GM. Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors. Journal of Leukocyte Biology. 58: 108-113. PMID 7616102 DOI: 10.1002/Jlb.58.1.108 |
0.357 |
|
1995 |
DeLeo FR, Nauseef WM, Jesaitis AJ, Burritt JB, Clark RA, Quinn MT. A domain of p47phox that interacts with human neutrophil flavocytochrome b558. The Journal of Biological Chemistry. 270: 26246-51. PMID 7592831 DOI: 10.1074/Jbc.270.44.26246 |
0.362 |
|
1995 |
Quinn MT, Bokoch GM. [28] Measurement of Rac translocation from cytosol to membranes in activated neutrophils Methods in Enzymology. 256: 256-267. PMID 7476440 DOI: 10.1016/0076-6879(95)56030-0 |
0.325 |
|
1994 |
Mukherjee G, Quinn MT, Linner JG, Jesaitis AJ. Remodeling of the plasma membrane after stimulation of neutrophils with f- Met-Leu-Phe and dihydrocytochalasin B: Identification of membrane subdomains containing NADPH oxidase activity Journal of Leukocyte Biology. 55: 685-694. PMID 8195693 DOI: 10.1002/Jlb.55.6.685 |
0.307 |
|
1993 |
Meier B, Jesaitis AJ, Emmendorffer A, Roesler J, Quinn MT. The cytochrome b-558 molecules involved in the fibroblast and polymorphonuclear leucocyte superoxide-generating NADPH oxidase systems are structurally and genetically distinct Biochemical Journal. 289: 481-486. PMID 7678734 DOI: 10.1042/Bj2890481 |
0.325 |
|
1992 |
Quinn M, Curnutte J, Parkos C, Mullen M, Scott P, Erickson R, Jesaitis A. Reconstitution of defective respiratory burst activity with partially purified human neutrophil cytochrome B in two genetic forms of chronic granulomatous disease: possible role of Rap1A Blood. 79: 2438-2445. DOI: 10.1182/Blood.V79.9.2438.2438 |
0.356 |
|
1992 |
Quinn M, Mullen M, Jesaitis A, Linner J. Subcellular distribution of the Rap1A protein in human neutrophils: colocalization and cotranslocation with cytochrome b559. Blood. 79: 1563-1573. DOI: 10.1182/Blood.V79.6.1563.Bloodjournal7961563 |
0.366 |
|
1991 |
Woodman RC, Ruedi JM, Jesaitis AJ, Okamura N, Quinn MT, Smith RM, Curnutte JT, Babior BM. Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils Journal of Clinical Investigation. 87: 1345-1351. PMID 1849148 DOI: 10.1172/Jci115138 |
0.36 |
|
1991 |
Bokoch GM, Quilliam LA, Bohl BP, Jesaitis AJ, Quinn MT. Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A Science. 254: 1794-1796. PMID 1763330 DOI: 10.1126/Science.1763330 |
0.34 |
|
1989 |
Quinn MT, Parkos CA, Jesaitis AJ. The lateral organization of components of the membrane skeleton and superoxide generation in the plasma membrane of stimulated human neutrophils Bba - Biomembranes. 987: 83-94. PMID 2557084 DOI: 10.1016/0005-2736(89)90458-6 |
0.325 |
|
1989 |
Quinn MT, Parkos CA, Walker L, Orkin SH, Dinauer MC, Jesaitis AJ. Association of a Ras-related protein with cytochrome b of human neutrophils Nature. 342: 198-200. PMID 2509942 DOI: 10.1038/342198A0 |
0.305 |
|
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