Patrick Doherty - Publications

Affiliations: 
King's College London, Guy's Campus, London, England, United Kingdom 
Area:
cell adhesion molecules, cell signalling

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lu L, Williams G, Doherty P. 2-Linoleoylglycerol Is a Partial Agonist of the Human Cannabinoid Type 1 Receptor that Can Suppress 2-Arachidonolyglycerol and Anandamide Activity. Cannabis and Cannabinoid Research. 4: 231-239. PMID 31872059 DOI: 10.1089/can.2019.0030  0.48
2019 Gatt A, Whitfield DR, Ballard C, Doherty P, Williams G. Alzheimer's Disease Progression in the 5×FAD Mouse Captured with a Multiplex Gene Expression Array. Journal of Alzheimer's Disease : Jad. PMID 31683485 DOI: 10.3233/JAD-190805  0.48
2019 Williams G, Gatt A, Clarke E, Corcoran J, Doherty P, Chambers D, Ballard C. Drug repurposing for Alzheimer's disease based on transcriptional profiling of human iPSC-derived cortical neurons. Translational Psychiatry. 9: 220. PMID 31492831 DOI: 10.1038/s41398-019-0555-x  0.48
2019 Frost J, Wingham J, Britten N, Greaves C, Abraham C, Warren FC, Jolly K, Doherty PJ, Miles J, Singh SJ, Paul K, Taylor R, Dalal H. Home-based rehabilitation for heart failure with reduced ejection fraction: mixed methods process evaluation of the REACH-HF multicentre randomised controlled trial. Bmj Open. 9: e026039. PMID 31377692 DOI: 10.1136/bmjopen-2018-026039  0.32
2019 Hompoonsup S, Chambers D, Doherty P, Williams G. No transcriptional evidence for active Na channels in two classes of cancer cell. Channels (Austin, Tex.). 13: 311-320. PMID 31329011 DOI: 10.1080/19336950.2019.1644858  0.48
2019 Fletcher EJR, Jamieson AD, Williams G, Doherty P, Duty S. Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats. Scientific Reports. 9: 8336. PMID 31171821 DOI: 10.1038/s41598-019-44803-1  0.48
2019 Wingham J, Frost J, Britten N, Greaves C, Abraham C, Warren FC, Jolly K, Miles J, Paul K, Doherty PJ, Singh S, Davies R, Noonan M, Dalal H, Taylor RS. Caregiver outcomes of the REACH-HF multicentre randomized controlled trial of home-based rehabilitation for heart failure with reduced ejection fraction. European Journal of Cardiovascular Nursing : Journal of the Working Group On Cardiovascular Nursing of the European Society of Cardiology. 1474515119850011. PMID 31117815 DOI: 10.1177/1474515119850011  0.32
2019 Taylor RS, Sadler S, Dalal HM, Warren FC, Jolly K, Davis RC, Doherty P, Miles J, Greaves C, Wingham J, Hillsdon M, Abraham C, Frost J, Singh S, Hayward C, et al. The cost effectiveness of REACH-HF and home-based cardiac rehabilitation compared with the usual medical care for heart failure with reduced ejection fraction: A decision model-based analysis. European Journal of Preventive Cardiology. 2047487319833507. PMID 30884975 DOI: 10.1177/2047487319833507  0.32
2018 Dalal HM, Taylor RS, Jolly K, Davis RC, Doherty P, Miles J, van Lingen R, Warren FC, Green C, Wingham J, Greaves C, Sadler S, Hillsdon M, Abraham C, Britten N, et al. The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial. European Journal of Preventive Cardiology. 2047487318806358. PMID 30304644 DOI: 10.1177/2047487318806358  0.32
2018 Lang CC, Smith K, Wingham J, Eyre V, Greaves CJ, Warren FC, Green C, Jolly K, Davis RC, Doherty PJ, Miles J, Britten N, Abraham C, Van Lingen R, Singh SJ, et al. A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: the REACH-HFpEF Pilot Study. Bmj Open. 8: e019649. PMID 29632081 DOI: 10.1136/bmjopen-2017-019649  0.32
2017 Bazenet C, Desmond H, Frank E, Doherty P, Eilers A, Gatchalian C, Glicksman M, Graczyk P, Gusovsky F, Ham J, Kaplan D, Klymkoswsky M, Kotkow K, Krolewski R, Lang P, et al. Lee Rubin: Our mentor and role model. Science (New York, N.Y.). 355: 806. PMID 28232547 DOI: 10.1126/science.aam8703  0.72
2016 Zhou Y, Howell FV, Glebov OO, Albrecht D, Williams G, Doherty P. Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools; implications for endocannabinoid signaling. Molecular and Cellular Neurosciences. PMID 27595600 DOI: 10.1016/j.mcn.2016.08.011  0.52
2016 Harrison AS, Sumner J, McMillan D, Doherty P. Relationship between employment and mental health outcomes following Cardiac Rehabilitation: an observational analysis from the National Audit of Cardiac Rehabilitation. International Journal of Cardiology. 220: 851-854. PMID 27394985 DOI: 10.1016/j.ijcard.2016.06.142  1
2016 Singh PK, Markwick R, Lu L, Howell FV, Williams G, Doherty P. Assay and inhibition of the purified catalytic domain of diacylglycerol lipase beta. Biochemistry. PMID 27115711 DOI: 10.1021/acs.biochem.6b00221  0.52
2016 Singh PK, Markwick R, Howell FV, Williams G, Doherty P. A novel live cell assay to measure diacylglycerol lipase α activity. Bioscience Reports. PMID 27013337 DOI: 10.1042/BSR20160073  0.52
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain. Plos One. 10: e0126478. PMID 25945928 DOI: 10.1371/journal.pone.0126478  1
2015 Zhou Y, Oudin MJ, Gajendra S, Sonego M, Falenta K, Williams G, Lalli G, Doherty P. Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream. Molecular and Cellular Neurosciences. 64: 32-43. PMID 25481343 DOI: 10.1016/j.mcn.2014.12.001  1
2015 Piepoli MF, Corrà U, Abreu A, Cupples M, Davos C, Doherty P, Höfer S, Garcia-Porrero E, Rauch B, Vigorito C, Völler H, Schmid JP. Challenges in secondary prevention of cardiovascular diseases: a review of the current practice. International Journal of Cardiology. 180: 114-9. PMID 25438230 DOI: 10.1016/j.ijcard.2014.11.107  1
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain Plos One. 10. DOI: 10.1371/journal.pone.0126478  1
2014 Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/nrn3846  1
2014 Keimpema E, Hökfelt T, Harkany T, Doherty P. The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond. The European Journal of Neuroscience. 39: 334-43. PMID 24494674 DOI: 10.1111/ejn.12431  1
2014 Das A, Gajendra S, Falenta K, Oudin MJ, Peschard P, Feng S, Wu B, Marshall CJ, Doherty P, Guo W, Lalli G. RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development. Journal of Cell Science. 127: 686-99. PMID 24284074 DOI: 10.1242/jcs.145037  1
2013 Sonego M, Zhou Y, Oudin MJ, Doherty P, Lalli G. In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices. Journal of Visualized Experiments : Jove. PMID 24326479 DOI: 10.3791/50905  1
2013 Falenta K, Gajendra S, Sonego M, Doherty P, Lalli G. Nucleofection of rodent neuroblasts to study neuroblast migration in vitro. Journal of Visualized Experiments : Jove. e50989. PMID 24300093 DOI: 10.3791/50989  1
2013 Williams G, Zentar MP, Gajendra S, Sonego M, Doherty P, Lalli G. Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11. Plos One. 8: e78478. PMID 24244313 DOI: 10.1371/journal.pone.0078478  1
2013 Sonego M, Gajendra S, Parsons M, Ma Y, Hobbs C, Zentar MP, Williams G, Machesky LM, Doherty P, Lalli G. Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12171-85. PMID 23884926 DOI: 10.1523/JNEUROSCI.0653-13.2013  1
2013 Tortoriello G, Rhodes BP, Takacs SM, Stuart JM, Basnet A, Raboune S, Widlanski TS, Doherty P, Harkany T, Bradshaw HB. Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides. Plos One. 8: e67865. PMID 23874457 DOI: 10.1371/journal.pone.0067865  1
2013 Keimpema E, Alpár A, Howell F, Malenczyk K, Hobbs C, Hurd YL, Watanabe M, Sakimura K, Kano M, Doherty P, Harkany T. Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling. Scientific Reports. 3: 2093. PMID 23806960 DOI: 10.1038/srep02093  1
2013 Lewin R, Doherty P. Cardiac rehabilitation and mortality reduction after myocardial infarction: the emperor's new clothes? Evidence in favour of cardiac rehabilitation. Heart (British Cardiac Society). 99: 909-11. PMID 23644410 DOI: 10.1136/heartjnl-2013-303704  0.32
2013 Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/pnas.1212563110  1
2013 Sütterlin P, Williams EJ, Chambers D, Saraf K, von Schack D, Reisenberg M, Doherty P, Williams G. The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function. Molecular and Cellular Neurosciences. 52: 20-30. PMID 23085403 DOI: 10.1016/j.mcn.2012.10.006  1
2012 Reisenberg M, Singh PK, Williams G, Doherty P. The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 3264-75. PMID 23108545 DOI: 10.1098/rstb.2011.0387  1
2012 Bryson JB, Hobbs C, Parsons MJ, Bosch KD, Pandraud A, Walsh FS, Doherty P, Greensmith L. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 3871-82. PMID 22678056 DOI: 10.1093/hmg/dds215  1
2012 Doherty P, Lewin R. The RAMIT trial, a pragmatic RCT of cardiac rehabilitation versus usual care: what does it tell us? Heart (British Cardiac Society). 98: 605-6. PMID 22505460 DOI: 10.1136/heartjnl-2012-301728  0.32
2012 Czysz K, Minger S, Thomas N, Doherty P. Removal notice to: "Development of human embryonic stem cell-derived hepatic cells for toxicology analysis" [Toxicology 290 (2011) 113] Toxicology. 302: 318. DOI: 10.1016/j.tox.2012.10.001  1
2011 Oudin MJ, Hobbs C, Doherty P. DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis. The European Journal of Neuroscience. 34: 1634-46. PMID 22103420 DOI: 10.1111/j.1460-9568.2011.07831.x  1
2011 Dalal HM, Wingham J, Lewin R, Doherty P, Taylor RS. Involving primary care and cardiac rehabilitation in a reorganised service could improve outcomes. Heart (British Cardiac Society). 97: 1191; discussion 119. PMID 21685484 DOI: 10.1136/heartjnl-2011-300326  0.32
2011 Oudin MJ, Gajendra S, Williams G, Hobbs C, Lalli G, Doherty P. Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4000-11. PMID 21411643 DOI: 10.1523/JNEUROSCI.5483-10.2011  1
2010 Gao Y, Deng K, Cao Z, Graziani EI, Gilbert AM, Koehn FE, Wood A, Doherty P, Walsh FS. Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons. Journal of Neurochemistry. 113: 1331-42. PMID 20345749 DOI: 10.1111/j.1471-4159.2010.06704.x  1
2010 Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, Shen R, Zhang MY, Strassle BW, Lu P, Mark L, Piesla MJ, Deng K, Kouranova EV, Ring RH, ... ... Doherty P, et al. Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2017-24. PMID 20147530 DOI: 10.1523/JNEUROSCI.5693-09.2010  1
2010 Goncalves MB, Williams EJ, Yip P, Yáñez-Muñoz RJ, Williams G, Doherty P. The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain. British Journal of Pharmacology. 159: 1118-25. PMID 20136845 DOI: 10.1111/j.1476-5381.2009.00618.x  1
2010 Deng K, Gao Y, Cao Z, Graziani EI, Wood A, Doherty P, Walsh FS. Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters. The Journal of Biological Chemistry. 285: 6425-33. PMID 20018888 DOI: 10.1074/jbc.M109.071548  1
2010 Agudo M, Yip P, Davies M, Bradbury E, Doherty P, McMahon S, Maden M, Corcoran JP. A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord. Neurobiology of Disease. 37: 147-55. PMID 19800972 DOI: 10.1016/j.nbd.2009.09.018  1
2010 Walker DJ, Suetterlin P, Reisenberg M, Williams G, Doherty P. Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription. Journal of Neuroscience Research. 88: 735-45. PMID 19798744 DOI: 10.1002/jnr.22251  1
2010 Cao Z, Gao Y, Deng K, Williams G, Doherty P, Walsh FS. Receptors for myelin inhibitors: Structures and therapeutic opportunities. Molecular and Cellular Neurosciences. 43: 1-14. PMID 19619659 DOI: 10.1016/j.mcn.2009.07.008  1
2009 Maison P, Walker DJ, Walsh FS, Williams G, Doherty P. BDNF regulates neuronal sensitivity to endocannabinoids. Neuroscience Letters. 467: 90-4. PMID 19818836 DOI: 10.1016/j.neulet.2009.10.011  1
2008 Harkany T, Mackie K, Doherty P. Wiring and firing neuronal networks: endocannabinoids take center stage. Current Opinion in Neurobiology. 18: 338-45. PMID 18801434 DOI: 10.1016/j.conb.2008.08.007  1
2008 Goncalves MB, Suetterlin P, Yip P, Molina-Holgado F, Walker DJ, Oudin MJ, Zentar MP, Pollard S, Yáñez-Muñoz RJ, Williams G, Walsh FS, Pangalos MN, Doherty P. A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner. Molecular and Cellular Neurosciences. 38: 526-36. PMID 18562209 DOI: 10.1016/j.mcn.2008.05.001  1
2008 Williams G, Wood A, Williams EJ, Gao Y, Mercado ML, Katz A, Joseph-McCarthy D, Bates B, Ling HP, Aulabaugh A, Zaccardi J, Xie Y, Pangalos MN, Walsh FS, Doherty P. Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. The Journal of Biological Chemistry. 283: 16641-52. PMID 18411262 DOI: 10.1074/jbc.M802067200  1
2008 Watson S, Chambers D, Hobbs C, Doherty P, Graham A. The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation. Molecular and Cellular Neurosciences. 38: 89-97. PMID 18378465 DOI: 10.1016/j.mcn.2008.02.001  1
2008 Molina-Holgado F, Doherty P, Williams G. Tandem repeat peptide strategy for the design of neurotrophic factor mimetics. Cns & Neurological Disorders Drug Targets. 7: 110-9. PMID 18289037 DOI: 10.2174/187152708783885200  1
2008 Cosker KE, Shadan S, van Diepen M, Morgan C, Li M, Allen-Baume V, Hobbs C, Doherty P, Cockcroft S, Eickholt BJ. Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons. Journal of Cell Science. 121: 796-803. PMID 18285448 DOI: 10.1242/jcs.019166  1
2007 Orrell A, Doherty P, Miles J, Lewin R. Development and validation of a very brief questionnaire measure of physical activity in adults with coronary heart disease. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 14: 615-23. PMID 17925619 DOI: 10.1097/HJR.0b013e3280ecfd56  0.32
2007 Orrell A, Doherty P, Coulton S, Miles J, Stamatakis E, Lewin R. Failure to validate the Health Survey for England physical activity module in a cardiac population. Health Policy (Amsterdam, Netherlands). 84: 262-8. PMID 17498835 DOI: 10.1016/j.healthpol.2007.03.004  0.32
2006 Sanchez-Heras E, Howell FV, Williams G, Doherty P. The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule. The Journal of Biological Chemistry. 281: 35208-16. PMID 17005551 DOI: 10.1074/jbc.M608655200  1
2006 Holzbaur EL, Howland DS, Weber N, Wallace K, She Y, Kwak S, Tchistiakova LA, Murphy E, Hinson J, Karim R, Tan XY, Kelley P, McGill KC, Williams G, Hobbs C, ... Doherty P, et al. Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis. Neurobiology of Disease. 23: 697-707. PMID 16837207 DOI: 10.1016/j.nbd.2006.05.009  1
2005 Williams G, Eickholt BJ, Maison P, Prinjha R, Walsh FS, Doherty P. A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists. Journal of Neurochemistry. 92: 1180-90. PMID 15715668 DOI: 10.1111/j.1471-4159.2004.02950.x  1
2005 Williams G, Williams EJ, Maison P, Pangalos MN, Walsh FS, Doherty P. Overcoming the inhibitors of myelin with a novel neurotrophin strategy. The Journal of Biological Chemistry. 280: 5862-9. PMID 15572360 DOI: 10.1074/jbc.M411121200  1
2004 Williams G, Doherty P. Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs. Bmc Bioinformatics. 5: 153. PMID 15491497 DOI: 10.1186/1471-2105-5-153  1
2004 Begbie J, Doherty P, Graham A. Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo. Journal of Anatomy. 205: 213-8. PMID 15379926 DOI: 10.1111/j.0021-8782.2004.00325.x  1
2004 Forni JJ, Romani S, Doherty P, Tear G. Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless. Molecular and Cellular Neurosciences. 26: 282-91. PMID 15207853 DOI: 10.1016/j.mcn.2004.02.003  1
2004 Skaper SD, Facci L, Williams G, Williams EJ, Walsh FS, Doherty P. A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade. Molecular and Cellular Neurosciences. 26: 17-23. PMID 15121175 DOI: 10.1016/j.mcn.2003.12.015  1
2003 Bisogno T, Howell F, Williams G, Minassi A, Cascio MG, Ligresti A, Matias I, Schiano-Moriello A, Paul P, Williams EJ, Gangadharan U, Hobbs C, Di Marzo V, Doherty P. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. The Journal of Cell Biology. 163: 463-8. PMID 14610053 DOI: 10.1083/jcb.200305129  1
2003 Williams EJ, Walsh FS, Doherty P. The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response. The Journal of Cell Biology. 160: 481-6. PMID 12578907 DOI: 10.1083/jcb.200210164  1
2002 Hivert B, Liu Z, Chuang CY, Doherty P, Sundaresan V. Robo1 and Robo2 are homophilic binding molecules that promote axonal growth. Molecular and Cellular Neurosciences. 21: 534-45. PMID 12504588 DOI: 10.1006/mcne.2002.1193  1
2002 Chadborn N, Eickholt B, Doherty P, Bolsover S. Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate. The European Journal of Neuroscience. 15: 1891-8. PMID 12099895 DOI: 10.1046/j.1460-9568.2002.02033.x  1
2002 Eickholt BJ, Walsh FS, Doherty P. An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. The Journal of Cell Biology. 157: 211-7. PMID 11956225 DOI: 10.1083/jcb.200201098  1
2002 Williams G, Williams EJ, Doherty P. Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists. The Journal of Biological Chemistry. 277: 4361-7. PMID 11726665 DOI: 10.1074/jbc.M109185200  1
2001 Williams EJ, Williams G, Howell FV, Skaper SD, Walsh FS, Doherty P. Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth. The Journal of Biological Chemistry. 276: 43879-86. PMID 11571292 DOI: 10.1074/jbc.M105876200  1
2001 Dunican DJ, Doherty P. Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways. Biopolymers. 60: 45-60. PMID 11376432 DOI: 10.1002/1097-0282(2001)60:1<45::AID-BIP1003>3.0.CO;2-9  1
2001 Dunican DJ, Williams EJ, Howell FV, Doherty P. Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 255-64. PMID 11373272  1
2001 Franceschini I, Angata K, Ong E, Hong A, Doherty P, Fukuda M. Polysialyltransferase ST8Sia II (STX) polysialylates all of the major isoforms of NCAM and facilitates neurite outgrowth. Glycobiology. 11: 231-9. PMID 11320061  1
2001 Utton MA, Eickholt B, Howell FV, Wallis J, Doherty P. Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells. Journal of Neurochemistry. 76: 1421-30. PMID 11238727 DOI: 10.1046/j.1471-4159.2001.00140.x  1
2000 Doherty P, Williams G, Williams EJ. CAMs and axonal growth: a critical evaluation of the role of calcium and the MAPK cascade. Molecular and Cellular Neurosciences. 16: 283-95. PMID 11085868 DOI: 10.1006/mcne.2000.0907  1
2000 Skaper SD, Kee WJ, Facci L, Macdonald G, Doherty P, Walsh FS. The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects. Journal of Neurochemistry. 75: 1520-7. PMID 10987832 DOI: 10.1046/j.1471-4159.2000.0751520.x  1
2000 Dunican DJ, Doherty P. The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility. Molecular Cell Biology Research Communications : McBrc. 3: 255-63. PMID 10964748 DOI: 10.1006/mcbr.2000.0225  1
2000 Rønn LC, Doherty P, Holm A, Berezin V, Bock E. Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation. Journal of Neurochemistry. 75: 665-71. PMID 10899941 DOI: 10.1046/j.1471-4159.2000.0750665.x  1
2000 Williams EJ, Williams G, Gour B, Blaschuk O, Doherty P. INP, a novel N-cadherin antagonist targeted to the amino acids that flank the HAV motif. Molecular and Cellular Neurosciences. 15: 456-64. PMID 10833302 DOI: 10.1006/mcne.2000.0847  1
2000 Schnädelbach O, Blaschuk OW, Symonds M, Gour BJ, Doherty P, Fawcett JW. N-Cadherin influences migration of oligodendrocytes on astrocyte monolayers Molecular and Cellular Neurosciences. 15: 288-302. PMID 10736205 DOI: 10.1006/mcne.1999.0819  1
2000 Vawter MP, Frye MA, Hemperly JJ, VanderPutten DM, Usen N, Doherty P, Saffell JL, Issa F, Post RM, Wyatt RJ, Freed WJ. Elevated concentration of N-CAM VASE isoforms in schizophrenia. Journal of Psychiatric Research. 34: 25-34. PMID 10696830 DOI: 10.1016/S0022-3956(99)00026-6  1
2000 Williams E, Williams G, Gour BJ, Blaschuk OW, Doherty P. A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motif. The Journal of Biological Chemistry. 275: 4007-12. PMID 10660557 DOI: 10.1074/jbc.275.6.4007  1
1999 Västrik I, Eickholt BJ, Walsh FS, Ridley A, Doherty P. Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32. Current Biology : Cb. 9: 991-8. PMID 10508610 DOI: 10.1016/S0960-9822(99)80447-3  1
1999 Davies SW, Sathasivam K, Hobbs C, Doherty P, Mangiarini L, Scherzinger E, Wanker EE, Bates GP. Detection of polyglutamine aggregation in mouse models. Methods in Enzymology. 309: 687-701. PMID 10507055 DOI: 10.1016/S0076-6879(99)09045-X  1
1999 Rønn LC, Olsen M, Ostergaard S, Kiselyov V, Berezin V, Mortensen MT, Lerche MH, Jensen PH, Soroka V, Saffell JL, Doherty P, Poulsen FM, Bock E, Holm A, Saffells JL. Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides. Nature Biotechnology. 17: 1000-5. PMID 10504702 DOI: 10.1038/13697  1
1999 Sathasivam K, Hobbs C, Mangiarini L, Mahal A, Turmaine M, Doherty P, Davies SW, Bates GP. Transgenic models of Huntington's disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 963-9. PMID 10434294 DOI: 10.1098/rstb.1999.0447  1
1999 Drosopoulos NE, Walsh FS, Doherty P. A soluble version of the receptor-like protein tyrosine phosphatase kappa stimulates neurite outgrowth via a Grb2/MEK1-dependent signaling cascade. Molecular and Cellular Neurosciences. 13: 441-9. PMID 10383829 DOI: 10.1006/mcne.1999.0758  1
1999 Bamberg JA, Baumgartner S, Betz H, Bolz J, Chedotal A, Christensen CRL, Comoglio PM, Culotti JG, Doherty P, Drabkin H, Ensser A, Fishman MC, Fleckenstein B, Freeman GJ, Fujisawa H, et al. Unified nomenclature for the semaphorins/collapsins [1] Cell. 97: 551-552. PMID 10367884 DOI: 10.1016/S0092-8674(00)80766-7  1
1999 Buttery PC, Mallawaarachchi CM, Milner R, Doherty P, ffrench-Constant C. Mapping regions of the beta1 integrin cytoplasmic domain involved in migration and survival in primary oligodendrocyte precursors using cell-permeable homeopeptides. Biochemical and Biophysical Research Communications. 259: 121-7. PMID 10334926 DOI: 10.1006/bbrc.1999.0726  1
1999 Williams EJ, Doherty P. Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway. Molecular and Cellular Neurosciences. 13: 272-80. PMID 10328886 DOI: 10.1006/mcne.1999.0750  1
1999 Eickholt BJ, Mackenzie SL, Graham A, Walsh FS, Doherty P. Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development (Cambridge, England). 126: 2181-9. PMID 10207143  1
1999 Sathasivam K, Hobbs C, Turmaine M, Mangiarini L, Mahal A, Bertaux F, Wanker EE, Doherty P, Davies SW, Bates GP. Formation of polyglutamine inclusions in non-CNS tissue. Human Molecular Genetics. 8: 813-22. PMID 10196370  1
1999 Shamim H, Mahmood R, Logan C, Doherty P, Lumsden A, Mason I. Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain. Development (Cambridge, England). 126: 945-59. PMID 9927596  1
1998 Bacon CL, Berezin V, Bode G, Bock E, Bojic U, Doherty P, Ehlers K, Ellerbeck U, Julien P, Kawa A, Maar TE, Nau H, Pirovano R, Regan CM, Schousboe A, et al. Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency. Toxicology in Vitro : An International Journal Published in Association With Bibra. 12: 101-9. PMID 20654391 DOI: 10.1016/S0887-2333(97)00100-8  1
1998 Meiri KF, Saffell JL, Walsh FS, Doherty P. Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10429-37. PMID 9852580 DOI: 10.1523/JNEUROSCI.18-24-10429.1998  1
1998 Calvet S, Doherty P, Prochiantz A. Identification of a signaling pathway activated specifically in the somatodendritic compartment by a heparan sulfate that regulates dendrite growth Journal of Neuroscience. 18: 9751-9765. PMID 9822735  1
1998 Derossi D, Williams EJ, Green PJ, Dunican DJ, Doherty P. Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide. Biochemical and Biophysical Research Communications. 251: 148-52. PMID 9790922 DOI: 10.1006/bbrc.1998.9444  1
1998 Kenwrick S, Doherty P. Neural cell adhesion molecule L1: Relating disease to function Bioessays. 20: 668-675. PMID 9780841 DOI: 10.1002/(SICI)1521-1878(199808)20:8<668::AID-BIES10>3.0.CO;2-X  1
1998 Tucker AS, Markham HJ, Green P, Doherty P, Sharpe PT. A novel approach for inhibiting growth factor signalling in murine tooth development: Inhibition of FGF's European Journal of Oral Sciences. 106: 122-125. PMID 9541213  1
1998 Simson R, Yang B, Moore SE, Doherty P, Walsh FS, Jacobson KA. Structural mosaicism on the submicron scale in the plasma membrane. Biophysical Journal. 74: 297-308. PMID 9449330 DOI: 10.1016/S0006-3495(98)77787-2  1
1997 Green PJ, Walsh FS, Doherty P. Signal transduction mechanisms underlying axonal growth responses stimulated by cell adhesion molecules. Revue Neurologique. 153: 509-14. PMID 9684000  1
1997 Walsh FS, Doherty P. Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annual Review of Cell and Developmental Biology. 13: 425-56. PMID 9442880 DOI: 10.1146/annurev.cellbio.13.1.425  1
1997 Jacobson KA, Moore SE, Yang B, Doherty P, Gordon GW, Walsh FS. Cellular determinants of the lateral mobility of neural cell adhesion molecules. Biochimica Et Biophysica Acta. 1330: 138-44. PMID 9408166 DOI: 10.1016/S0005-2736(97)00128-4  1
1997 Eickholt BJ, Morrow R, Walsh FS, Doherty P. Structural features of collapsin required for biological activity and distribution of binding sites in the developing chick. Molecular and Cellular Neurosciences. 9: 358-71. PMID 9361274 DOI: 10.1006/mcne.1997.0636  1
1997 Tang S, Woodhall RW, Shen YJ, deBellard ME, Saffell JL, Doherty P, Walsh FS, Filbin MT. Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration. Molecular and Cellular Neurosciences. 9: 333-46. PMID 9361272 DOI: 10.1006/mcne.1997.0633  1
1997 Viollet C, Doherty P. CAMs and the FGF receptor: An interacting role in axonal growth Cell and Tissue Research. 290: 451-455. PMID 9321709 DOI: 10.1007/s004410050952  1
1997 Williams EJ, Dunican DJ, Green PJ, Howell FV, Derossi D, Walsh FS, Doherty P. Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide. The Journal of Biological Chemistry. 272: 22349-54. PMID 9268386 DOI: 10.1074/jbc.272.35.22349  1
1997 Walsh FS, Meiri K, Doherty P. Cell signalling and CAM-mediated neurite outgrowth. Society of General Physiologists Series. 52: 221-6. PMID 9210232  1
1997 Saffell JL, Williams EJ, Mason IJ, Walsh FS, Doherty P. Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron. 18: 231-42. PMID 9052794 DOI: 10.1016/S0896-6273(00)80264-0  1
1996 Doherty P, Smith P, Walsh FS. Shared cell adhesion molecule (CAM) homology domains point to CAMs signalling via FGF receptors. Perspectives On Developmental Neurobiology. 4: 157-68. PMID 9168198  1
1996 Brittis PA, Silver J, Walsh FS, Doherty P. Fibroblast Growth Factor Receptor Function Is Required for the Orderly Projection of Ganglion Cell Axons in the Developing Mammalian Retina Molecular and Cellular Neurosciences. 8: 120-8. PMID 8954627 DOI: 10.1006/mcne.1996.0051  1
1996 Doherty P, Walsh FS. CAM-FGF Receptor Interactions: A Model for Axonal Growth Molecular and Cellular Neurosciences. 8: 99-111. PMID 8954625 DOI: 10.1006/mcne.1996.0049  1
1996 Walsh FS, Doherty P. Cell adhesion molecules and neuronal regeneration. Current Opinion in Cell Biology. 8: 707-13. PMID 8939655 DOI: 10.1016/S0955-0674(96)80113-X  1
1996 Hall H, Walsh FS, Doherty P. Review: a role for the FGF receptor in the axonal growth response stimulated by cell adhesion molecules? Cell Adhesion and Communication. 3: 441-50. PMID 8807188 DOI: 10.3109/15419069609081021  1
1996 Baldwin TJ, Fazeli MS, Doherty P, Walsh FS. Elucidation of the molecular actions of NCAM and structurally related cell adhesion molecules. Journal of Cellular Biochemistry. 61: 502-13. PMID 8806073 DOI: 10.1002/(SICI)1097-4644(19960616)61:4<502::AID-JCB3>3.0.CO;2-S  1
1996 Hall H, Williams EJ, Moore SE, Walsh FS, Prochiantz A, Doherty P. Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide. Current Biology : Cb. 6: 580-7. PMID 8805278  1
1996 Green PJ, Walsh FS, Doherty P. Promiscuity of fibroblast growth factor receptors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 639-46. PMID 8760337 DOI: 10.1002/bies.950180807  1
1995 Williams EJ, Mittal B, Walsh FS, Doherty P. FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. Journal of Cell Science. 108: 3523-30. PMID 8586663  1
1995 Saffell JL, Williams EJ, Doherty P, Walsh FW. Axonal growth mediated by cell adhesion molecules requires activation of fibroblast growth factor receptors. Biochemical Society Transactions. 23: 469-70. PMID 8566363 DOI: 10.1042/bst0230469  1
1995 Doherty P, Williams E, Walsh FS. A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth. Neuron. 14: 57-66. PMID 7826641 DOI: 10.1016/0896-6273(95)90240-6  1
1995 Williams EJ, Mittal B, Walsh FS, Doherty P. A Ca2+/calmodulin kinase inhibitor, KN-62, inhibits neurite outgrowth stimulated by CAMs and FGF. Molecular and Cellular Neurosciences. 6: 69-79. PMID 7599959 DOI: 10.1006/mcne.1995.1007  1
1994 Williams EJ, Walsh FS, Doherty P. Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth. The Journal of Cell Biology. 124: 1029-37. PMID 8132706 DOI: 10.1083/jcb.124.6.1029  1
1994 Williams EJ, Walsh FS, Doherty P. The production of arachidonic acid can account for calcium channel activation in the second messenger pathway underlying neurite outgrowth stimulated by NCAM, N-cadherin, and L1. Journal of Neurochemistry. 62: 1231-4. PMID 8113807 DOI: 10.1046/j.1471-4159.1994.62031231.x  1
1994 Williams EJ, Furness J, Walsh FS, Doherty P. Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development (Cambridge, England). 120: 1685-93. PMID 8050374  1
1994 Williams EJ, Furness J, Walsh FS, Doherty P. Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron. 13: 583-94. PMID 7917292 DOI: 10.1016/0896-6273(94)90027-2  1
1994 Doherty P, Furness J, Williams EJ, Walsh FS. Neurite outgrowth stimulated by the tyrosine kinase inhibitor herbimycin A requires activation of tyrosine kinases and protein kinase C. Journal of Neurochemistry. 62: 2124-31. PMID 7514647 DOI: 10.1046/j.1471-4159.1994.62062124.x  1
1992 Williams EJ, Doherty P, Turner G, Reid RA, Hemperly JJ, Walsh FS. Calcium influx into neurons can solely account for cell contact-dependent neurite outgrowth stimulated by transfected L1. The Journal of Cell Biology. 119: 883-92. PMID 1429842 DOI: 10.1083/jcb.119.4.883  1
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