Patrick Doherty - Publications

Affiliations: 
King's College London, Guy's Campus, London, England, United Kingdom 
Area:
cell adhesion molecules, cell signalling

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhou Y, Howell FV, Glebov OO, Albrecht D, Williams G, Doherty P. Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools; implications for endocannabinoid signaling. Molecular and Cellular Neurosciences. PMID 27595600 DOI: 10.1016/J.Mcn.2016.08.011  0.309
2016 Singh PK, Markwick R, Howell FV, Williams G, Doherty P. A novel live cell assay to measure diacylglycerol lipase α activity. Bioscience Reports. PMID 27013337 DOI: 10.1042/Bsr20160073  0.322
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain. Plos One. 10: e0126478. PMID 25945928 DOI: 10.1371/Journal.Pone.0126478  0.659
2015 Zhou Y, Oudin MJ, Gajendra S, Sonego M, Falenta K, Williams G, Lalli G, Doherty P. Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream. Molecular and Cellular Neurosciences. 64: 32-43. PMID 25481343 DOI: 10.1016/J.Mcn.2014.12.001  0.35
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain Plos One. 10. DOI: 10.1371/journal.pone.0126478  0.587
2014 Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/Nrn3846  0.324
2014 Das A, Gajendra S, Falenta K, Oudin MJ, Peschard P, Feng S, Wu B, Marshall CJ, Doherty P, Guo W, Lalli G. RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development. Journal of Cell Science. 127: 686-99. PMID 24284074 DOI: 10.1242/Jcs.145037  0.334
2013 Sonego M, Zhou Y, Oudin MJ, Doherty P, Lalli G. In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices. Journal of Visualized Experiments : Jove. PMID 24326479 DOI: 10.3791/50905  0.318
2013 Falenta K, Gajendra S, Sonego M, Doherty P, Lalli G. Nucleofection of rodent neuroblasts to study neuroblast migration in vitro. Journal of Visualized Experiments : Jove. e50989. PMID 24300093 DOI: 10.3791/50989  0.337
2013 Williams G, Zentar MP, Gajendra S, Sonego M, Doherty P, Lalli G. Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11. Plos One. 8: e78478. PMID 24244313 DOI: 10.1371/Journal.Pone.0078478  0.339
2013 Sonego M, Gajendra S, Parsons M, Ma Y, Hobbs C, Zentar MP, Williams G, Machesky LM, Doherty P, Lalli G. Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12171-85. PMID 23884926 DOI: 10.1523/Jneurosci.0653-13.2013  0.343
2013 Keimpema E, Alpár A, Howell F, Malenczyk K, Hobbs C, Hurd YL, Watanabe M, Sakimura K, Kano M, Doherty P, Harkany T. Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling. Scientific Reports. 3: 2093. PMID 23806960 DOI: 10.1038/Srep02093  0.331
2013 Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/Pnas.1212563110  0.366
2013 Sütterlin P, Williams EJ, Chambers D, Saraf K, von Schack D, Reisenberg M, Doherty P, Williams G. The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function. Molecular and Cellular Neurosciences. 52: 20-30. PMID 23085403 DOI: 10.1016/J.Mcn.2012.10.006  0.567
2012 Reisenberg M, Singh PK, Williams G, Doherty P. The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 3264-75. PMID 23108545 DOI: 10.1098/Rstb.2011.0387  0.358
2012 Bryson JB, Hobbs C, Parsons MJ, Bosch KD, Pandraud A, Walsh FS, Doherty P, Greensmith L. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 3871-82. PMID 22678056 DOI: 10.1093/Hmg/Dds215  0.509
2011 Oudin MJ, Hobbs C, Doherty P. DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis. The European Journal of Neuroscience. 34: 1634-46. PMID 22103420 DOI: 10.1111/J.1460-9568.2011.07831.X  0.319
2011 Oudin MJ, Gajendra S, Williams G, Hobbs C, Lalli G, Doherty P. Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4000-11. PMID 21411643 DOI: 10.1523/Jneurosci.5483-10.2011  0.341
2010 Gao Y, Deng K, Cao Z, Graziani EI, Gilbert AM, Koehn FE, Wood A, Doherty P, Walsh FS. Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons. Journal of Neurochemistry. 113: 1331-42. PMID 20345749 DOI: 10.1111/J.1471-4159.2010.06704.X  0.566
2010 Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, Shen R, Zhang MY, Strassle BW, Lu P, Mark L, Piesla MJ, Deng K, Kouranova EV, Ring RH, ... ... Doherty P, et al. Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2017-24. PMID 20147530 DOI: 10.1523/Jneurosci.5693-09.2010  0.524
2010 Goncalves MB, Williams EJ, Yip P, Yáñez-Muñoz RJ, Williams G, Doherty P. The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain. British Journal of Pharmacology. 159: 1118-25. PMID 20136845 DOI: 10.1111/J.1476-5381.2009.00618.X  0.33
2010 Deng K, Gao Y, Cao Z, Graziani EI, Wood A, Doherty P, Walsh FS. Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters. The Journal of Biological Chemistry. 285: 6425-33. PMID 20018888 DOI: 10.1074/Jbc.M109.071548  0.568
2010 Agudo M, Yip P, Davies M, Bradbury E, Doherty P, McMahon S, Maden M, Corcoran JP. A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord. Neurobiology of Disease. 37: 147-55. PMID 19800972 DOI: 10.1016/J.Nbd.2009.09.018  0.33
2010 Walker DJ, Suetterlin P, Reisenberg M, Williams G, Doherty P. Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription. Journal of Neuroscience Research. 88: 735-45. PMID 19798744 DOI: 10.1002/Jnr.22251  0.342
2010 Cao Z, Gao Y, Deng K, Williams G, Doherty P, Walsh FS. Receptors for myelin inhibitors: Structures and therapeutic opportunities. Molecular and Cellular Neurosciences. 43: 1-14. PMID 19619659 DOI: 10.1016/J.Mcn.2009.07.008  0.546
2009 Maison P, Walker DJ, Walsh FS, Williams G, Doherty P. BDNF regulates neuronal sensitivity to endocannabinoids. Neuroscience Letters. 467: 90-4. PMID 19818836 DOI: 10.1016/J.Neulet.2009.10.011  0.564
2008 Harkany T, Mackie K, Doherty P. Wiring and firing neuronal networks: endocannabinoids take center stage. Current Opinion in Neurobiology. 18: 338-45. PMID 18801434 DOI: 10.1016/J.Conb.2008.08.007  0.328
2008 Goncalves MB, Suetterlin P, Yip P, Molina-Holgado F, Walker DJ, Oudin MJ, Zentar MP, Pollard S, Yáñez-Muñoz RJ, Williams G, Walsh FS, Pangalos MN, Doherty P. A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner. Molecular and Cellular Neurosciences. 38: 526-36. PMID 18562209 DOI: 10.1016/J.Mcn.2008.05.001  0.538
2008 Williams G, Wood A, Williams EJ, Gao Y, Mercado ML, Katz A, Joseph-McCarthy D, Bates B, Ling HP, Aulabaugh A, Zaccardi J, Xie Y, Pangalos MN, Walsh FS, Doherty P. Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. The Journal of Biological Chemistry. 283: 16641-52. PMID 18411262 DOI: 10.1074/Jbc.M802067200  0.566
2008 Watson S, Chambers D, Hobbs C, Doherty P, Graham A. The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation. Molecular and Cellular Neurosciences. 38: 89-97. PMID 18378465 DOI: 10.1016/J.Mcn.2008.02.001  0.364
2008 Molina-Holgado F, Doherty P, Williams G. Tandem repeat peptide strategy for the design of neurotrophic factor mimetics. Cns & Neurological Disorders Drug Targets. 7: 110-9. PMID 18289037 DOI: 10.2174/187152708783885200  0.31
2008 Cosker KE, Shadan S, van Diepen M, Morgan C, Li M, Allen-Baume V, Hobbs C, Doherty P, Cockcroft S, Eickholt BJ. Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons. Journal of Cell Science. 121: 796-803. PMID 18285448 DOI: 10.1242/Jcs.019166  0.774
2006 Sanchez-Heras E, Howell FV, Williams G, Doherty P. The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule. The Journal of Biological Chemistry. 281: 35208-16. PMID 17005551 DOI: 10.1074/Jbc.M608655200  0.334
2006 Holzbaur EL, Howland DS, Weber N, Wallace K, She Y, Kwak S, Tchistiakova LA, Murphy E, Hinson J, Karim R, Tan XY, Kelley P, McGill KC, Williams G, Hobbs C, ... Doherty P, et al. Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis. Neurobiology of Disease. 23: 697-707. PMID 16837207 DOI: 10.1016/J.Nbd.2006.05.009  0.514
2005 Williams G, Eickholt BJ, Maison P, Prinjha R, Walsh FS, Doherty P. A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists. Journal of Neurochemistry. 92: 1180-90. PMID 15715668 DOI: 10.1111/J.1471-4159.2004.02950.X  0.699
2005 Williams G, Williams EJ, Maison P, Pangalos MN, Walsh FS, Doherty P. Overcoming the inhibitors of myelin with a novel neurotrophin strategy. The Journal of Biological Chemistry. 280: 5862-9. PMID 15572360 DOI: 10.1074/Jbc.M411121200  0.564
2004 Skaper SD, Facci L, Williams G, Williams EJ, Walsh FS, Doherty P. A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade. Molecular and Cellular Neurosciences. 26: 17-23. PMID 15121175 DOI: 10.1016/J.Mcn.2003.12.015  0.585
2003 Bisogno T, Howell F, Williams G, Minassi A, Cascio MG, Ligresti A, Matias I, Schiano-Moriello A, Paul P, Williams EJ, Gangadharan U, Hobbs C, Di Marzo V, Doherty P. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. The Journal of Cell Biology. 163: 463-8. PMID 14610053 DOI: 10.1083/Jcb.200305129  0.325
2003 Williams EJ, Walsh FS, Doherty P. The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response. The Journal of Cell Biology. 160: 481-6. PMID 12578907 DOI: 10.1083/Jcb.200210164  0.572
2002 Hivert B, Liu Z, Chuang CY, Doherty P, Sundaresan V. Robo1 and Robo2 are homophilic binding molecules that promote axonal growth. Molecular and Cellular Neurosciences. 21: 534-45. PMID 12504588 DOI: 10.1006/Mcne.2002.1193  0.385
2002 Chadborn N, Eickholt B, Doherty P, Bolsover S. Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate. The European Journal of Neuroscience. 15: 1891-8. PMID 12099895 DOI: 10.1046/J.1460-9568.2002.02033.X  0.619
2002 Eickholt BJ, Walsh FS, Doherty P. An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. The Journal of Cell Biology. 157: 211-7. PMID 11956225 DOI: 10.1083/Jcb.200201098  0.688
2002 Williams G, Williams EJ, Doherty P. Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists. The Journal of Biological Chemistry. 277: 4361-7. PMID 11726665 DOI: 10.1074/Jbc.M109185200  0.356
2001 Williams EJ, Williams G, Howell FV, Skaper SD, Walsh FS, Doherty P. Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth. The Journal of Biological Chemistry. 276: 43879-86. PMID 11571292 DOI: 10.1074/Jbc.M105876200  0.556
2001 Dunican DJ, Doherty P. Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways. Biopolymers. 60: 45-60. PMID 11376432 DOI: 10.1002/1097-0282(2001)60:1<45::Aid-Bip1003>3.0.Co;2-9  0.327
2001 Utton MA, Eickholt B, Howell FV, Wallis J, Doherty P. Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells. Journal of Neurochemistry. 76: 1421-30. PMID 11238727 DOI: 10.1046/J.1471-4159.2001.00140.X  0.668
2000 Doherty P, Williams G, Williams EJ. CAMs and axonal growth: a critical evaluation of the role of calcium and the MAPK cascade. Molecular and Cellular Neurosciences. 16: 283-95. PMID 11085868 DOI: 10.1006/Mcne.2000.0907  0.357
2000 Skaper SD, Kee WJ, Facci L, Macdonald G, Doherty P, Walsh FS. The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects. Journal of Neurochemistry. 75: 1520-7. PMID 10987832 DOI: 10.1046/J.1471-4159.2000.0751520.X  0.502
2000 Dunican DJ, Doherty P. The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility. Molecular Cell Biology Research Communications : McBrc. 3: 255-63. PMID 10964748 DOI: 10.1006/Mcbr.2000.0225  0.36
2000 Williams EJ, Williams G, Gour B, Blaschuk O, Doherty P. INP, a novel N-cadherin antagonist targeted to the amino acids that flank the HAV motif. Molecular and Cellular Neurosciences. 15: 456-64. PMID 10833302 DOI: 10.1006/Mcne.2000.0847  0.319
2000 Schnädelbach O, Blaschuk OW, Symonds M, Gour BJ, Doherty P, Fawcett JW. N-Cadherin influences migration of oligodendrocytes on astrocyte monolayers Molecular and Cellular Neurosciences. 15: 288-302. PMID 10736205 DOI: 10.1006/Mcne.1999.0819  0.341
2000 Williams E, Williams G, Gour BJ, Blaschuk OW, Doherty P. A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motif. The Journal of Biological Chemistry. 275: 4007-12. PMID 10660557 DOI: 10.1074/Jbc.275.6.4007  0.55
1999 Västrik I, Eickholt BJ, Walsh FS, Ridley A, Doherty P. Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32. Current Biology : Cb. 9: 991-8. PMID 10508610 DOI: 10.1016/S0960-9822(99)80447-3  0.688
1999 Drosopoulos NE, Walsh FS, Doherty P. A soluble version of the receptor-like protein tyrosine phosphatase kappa stimulates neurite outgrowth via a Grb2/MEK1-dependent signaling cascade. Molecular and Cellular Neurosciences. 13: 441-9. PMID 10383829 DOI: 10.1006/Mcne.1999.0758  0.502
1999 Bamberg JA, Baumgartner S, Betz H, Bolz J, Chedotal A, Christensen CRL, Comoglio PM, Culotti JG, Doherty P, Drabkin H, Ensser A, Fishman MC, Fleckenstein B, Freeman GJ, Fujisawa H, et al. Unified nomenclature for the semaphorins/collapsins [1] Cell. 97: 551-552. PMID 10367884 DOI: 10.1016/S0092-8674(00)80766-7  0.418
1999 Buttery PC, Mallawaarachchi CM, Milner R, Doherty P, ffrench-Constant C. Mapping regions of the beta1 integrin cytoplasmic domain involved in migration and survival in primary oligodendrocyte precursors using cell-permeable homeopeptides. Biochemical and Biophysical Research Communications. 259: 121-7. PMID 10334926 DOI: 10.1006/Bbrc.1999.0726  0.322
1999 Williams EJ, Doherty P. Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway. Molecular and Cellular Neurosciences. 13: 272-80. PMID 10328886 DOI: 10.1006/Mcne.1999.0750  0.341
1999 Eickholt BJ, Mackenzie SL, Graham A, Walsh FS, Doherty P. Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development (Cambridge, England). 126: 2181-9. PMID 10207143  0.668
1999 Sathasivam K, Hobbs C, Turmaine M, Mangiarini L, Mahal A, Bertaux F, Wanker EE, Doherty P, Davies SW, Bates GP. Formation of polyglutamine inclusions in non-CNS tissue. Human Molecular Genetics. 8: 813-22. PMID 10196370 DOI: 10.1093/Hmg/8.5.813  0.308
1998 Bacon CL, Berezin V, Bode G, Bock E, Bojic U, Doherty P, Ehlers K, Ellerbeck U, Julien P, Kawa A, Maar TE, Nau H, Pirovano R, Regan CM, Schousboe A, et al. Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency. Toxicology in Vitro : An International Journal Published in Association With Bibra. 12: 101-9. PMID 20654391 DOI: 10.1016/S0887-2333(97)00100-8  0.667
1998 Meiri KF, Saffell JL, Walsh FS, Doherty P. Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10429-37. PMID 9852580 DOI: 10.1523/Jneurosci.18-24-10429.1998  0.502
1998 Calvet S, Doherty P, Prochiantz A. Identification of a signaling pathway activated specifically in the somatodendritic compartment by a heparan sulfate that regulates dendrite growth Journal of Neuroscience. 18: 9751-9765. PMID 9822735 DOI: 10.1523/Jneurosci.18-23-09751.1998  0.349
1998 Derossi D, Williams EJ, Green PJ, Dunican DJ, Doherty P. Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide. Biochemical and Biophysical Research Communications. 251: 148-52. PMID 9790922 DOI: 10.1006/Bbrc.1998.9444  0.314
1998 Kenwrick S, Doherty P. Neural cell adhesion molecule L1: Relating disease to function Bioessays. 20: 668-675. PMID 9780841 DOI: 10.1002/(Sici)1521-1878(199808)20:8<668::Aid-Bies10>3.0.Co;2-X  0.348
1998 Simson R, Yang B, Moore SE, Doherty P, Walsh FS, Jacobson KA. Structural mosaicism on the submicron scale in the plasma membrane. Biophysical Journal. 74: 297-308. PMID 9449330 DOI: 10.1016/S0006-3495(98)77787-2  0.501
1997 Green PJ, Walsh FS, Doherty P. Signal transduction mechanisms underlying axonal growth responses stimulated by cell adhesion molecules. Revue Neurologique. 153: 509-14. PMID 9684000  0.441
1997 Walsh FS, Doherty P. Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annual Review of Cell and Developmental Biology. 13: 425-56. PMID 9442880 DOI: 10.1146/Annurev.Cellbio.13.1.425  0.585
1997 Jacobson KA, Moore SE, Yang B, Doherty P, Gordon GW, Walsh FS. Cellular determinants of the lateral mobility of neural cell adhesion molecules. Biochimica Et Biophysica Acta. 1330: 138-44. PMID 9408166 DOI: 10.1016/S0005-2736(97)00128-4  0.529
1997 Eickholt BJ, Morrow R, Walsh FS, Doherty P. Structural features of collapsin required for biological activity and distribution of binding sites in the developing chick. Molecular and Cellular Neurosciences. 9: 358-71. PMID 9361274 DOI: 10.1006/Mcne.1997.0636  0.688
1997 Tang S, Woodhall RW, Shen YJ, deBellard ME, Saffell JL, Doherty P, Walsh FS, Filbin MT. Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration. Molecular and Cellular Neurosciences. 9: 333-46. PMID 9361272 DOI: 10.1006/Mcne.1997.0633  0.553
1997 Viollet C, Doherty P. CAMs and the FGF receptor: An interacting role in axonal growth Cell and Tissue Research. 290: 451-455. PMID 9321709 DOI: 10.1007/S004410050952  0.382
1997 Williams EJ, Dunican DJ, Green PJ, Howell FV, Derossi D, Walsh FS, Doherty P. Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide. The Journal of Biological Chemistry. 272: 22349-54. PMID 9268386 DOI: 10.1074/Jbc.272.35.22349  0.558
1997 Walsh FS, Meiri K, Doherty P. Cell signalling and CAM-mediated neurite outgrowth. Society of General Physiologists Series. 52: 221-6. PMID 9210232  0.441
1997 Saffell JL, Williams EJ, Mason IJ, Walsh FS, Doherty P. Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron. 18: 231-42. PMID 9052794 DOI: 10.1016/S0896-6273(00)80264-0  0.703
1996 Doherty P, Smith P, Walsh FS. Shared cell adhesion molecule (CAM) homology domains point to CAMs signalling via FGF receptors. Perspectives On Developmental Neurobiology. 4: 157-68. PMID 9168198  0.542
1996 Brittis PA, Silver J, Walsh FS, Doherty P. Fibroblast Growth Factor Receptor Function Is Required for the Orderly Projection of Ganglion Cell Axons in the Developing Mammalian Retina Molecular and Cellular Neurosciences. 8: 120-8. PMID 8954627 DOI: 10.1006/Mcne.1996.0051  0.571
1996 Doherty P, Walsh FS. CAM-FGF Receptor Interactions: A Model for Axonal Growth Molecular and Cellular Neurosciences. 8: 99-111. PMID 8954625 DOI: 10.1006/Mcne.1996.0049  0.583
1996 Walsh FS, Doherty P. Cell adhesion molecules and neuronal regeneration. Current Opinion in Cell Biology. 8: 707-13. PMID 8939655 DOI: 10.1016/S0955-0674(96)80113-X  0.581
1996 Hall H, Walsh FS, Doherty P. Review: a role for the FGF receptor in the axonal growth response stimulated by cell adhesion molecules? Cell Adhesion and Communication. 3: 441-50. PMID 8807188 DOI: 10.3109/15419069609081021  0.502
1996 Baldwin TJ, Fazeli MS, Doherty P, Walsh FS. Elucidation of the molecular actions of NCAM and structurally related cell adhesion molecules. Journal of Cellular Biochemistry. 61: 502-13. PMID 8806073 DOI: 10.1002/(Sici)1097-4644(19960616)61:4<502::Aid-Jcb3>3.0.Co;2-S  0.502
1996 Hall H, Williams EJ, Moore SE, Walsh FS, Prochiantz A, Doherty P. Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide. Current Biology : Cb. 6: 580-7. PMID 8805278 DOI: 10.1016/S0960-9822(02)00544-4  0.672
1996 Green PJ, Walsh FS, Doherty P. Promiscuity of fibroblast growth factor receptors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 639-46. PMID 8760337 DOI: 10.1002/Bies.950180807  0.502
1996 Doherty P, Walsh FS. 94 PSA is a specific and positive regulator of the axonal growth response stimulated by NCAM International Journal of Developmental Neuroscience. 14: 73-73. DOI: 10.1016/0736-5748(96)80285-1  0.502
1995 Saffell JL, Doherty P, Tiveron MC, Morris RJ, Walsh FS. NCAM requires a cytoplasmic domain to function as a neurite outgrowth-promoting neuronal receptor. Molecular and Cellular Neurosciences. 6: 521-31. PMID 8742269 DOI: 10.1006/Mcne.1995.0004  0.502
1995 Williams EJ, Mittal B, Walsh FS, Doherty P. FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. Journal of Cell Science. 108: 3523-30. PMID 8586663  0.441
1995 Saffell JL, Williams EJ, Doherty P, Walsh FW. Axonal growth mediated by cell adhesion molecules requires activation of fibroblast growth factor receptors. Biochemical Society Transactions. 23: 469-70. PMID 8566363 DOI: 10.1042/Bst0230469  0.359
1995 Doherty P, Williams E, Walsh FS. A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth. Neuron. 14: 57-66. PMID 7826641 DOI: 10.1016/0896-6273(95)90240-6  0.684
1995 Doherty P, Fazeli MS, Walsh FS. The neural cell adhesion molecule and synaptic plasticity. Journal of Neurobiology. 26: 437-46. PMID 7775976 DOI: 10.1002/Neu.480260315  0.502
1995 Williams EJ, Mittal B, Walsh FS, Doherty P. A Ca2+/calmodulin kinase inhibitor, KN-62, inhibits neurite outgrowth stimulated by CAMs and FGF. Molecular and Cellular Neurosciences. 6: 69-79. PMID 7599959 DOI: 10.1006/Mcne.1995.1007  0.695
1994 Doherty P, Walsh FS. Signal transduction events underlying neurite outgrowth stimulated by cell adhesion molecules. Current Opinion in Neurobiology. 4: 49-55. PMID 8173325 DOI: 10.1016/0959-4388(94)90031-0  0.591
1994 Saffell JL, Walsh FS, Doherty P. Expression of NCAM containing VASE in neurons can account for a developmental loss in their neurite outgrowth response to NCAM in a cellular substratum. The Journal of Cell Biology. 125: 427-36. PMID 8163558 DOI: 10.1083/Jcb.125.2.427  0.502
1994 Williams EJ, Walsh FS, Doherty P. Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth. The Journal of Cell Biology. 124: 1029-37. PMID 8132706 DOI: 10.1083/Jcb.124.6.1029  0.682
1994 Williams EJ, Walsh FS, Doherty P. The production of arachidonic acid can account for calcium channel activation in the second messenger pathway underlying neurite outgrowth stimulated by NCAM, N-cadherin, and L1. Journal of Neurochemistry. 62: 1231-4. PMID 8113807 DOI: 10.1046/J.1471-4159.1994.62031231.X  0.55
1994 Williams EJ, Furness J, Walsh FS, Doherty P. Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development (Cambridge, England). 120: 1685-93. PMID 8050374  0.441
1994 Walsh FS, Skaper SD, Doherty P. Cell adhesion molecule (NCAM and N-cadherin)-dependent neurite outgrowth is modulated by gangliosides. Progress in Brain Research. 101: 113-8. PMID 8029444 DOI: 10.1016/S0079-6123(08)61943-3  0.502
1994 Williams EJ, Furness J, Walsh FS, Doherty P. Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron. 13: 583-94. PMID 7917292 DOI: 10.1016/0896-6273(94)90027-2  0.577
1994 Harper SJ, Bolsover SR, Walsh FS, Doherty P. Neurite outgrowth stimulated by L1 requires calcium influx into neurons but is not associated with changes in steady state levels of calcium in growth cones. Cell Adhesion and Communication. 2: 441-53. PMID 7842257 DOI: 10.3109/15419069409004454  0.502
1994 Mukhopadhyay G, Doherty P, Walsh FS, Crocker PR, Filbin MT. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron. 13: 757-67. PMID 7522484 DOI: 10.1016/0896-6273(94)90042-6  0.502
1994 Doherty P, Furness J, Williams EJ, Walsh FS. Neurite outgrowth stimulated by the tyrosine kinase inhibitor herbimycin A requires activation of tyrosine kinases and protein kinase C. Journal of Neurochemistry. 62: 2124-31. PMID 7514647 DOI: 10.1046/J.1471-4159.1994.62062124.X  0.554
1993 Harper SJ, Walsh FS, Doherty P. Neurite outgrowth of spinal neurons on tissue sections of embryonic muscle is largely integrin dependent. Neuroscience Letters. 159: 202-6. PMID 8264967 DOI: 10.1016/0304-3940(93)90834-8  0.502
1993 Walsh FS, Doherty P. Factors regulating the expression and function of calcium-independent cell adhesion molecules. Current Opinion in Cell Biology. 5: 791-6. PMID 8240822 DOI: 10.1016/0955-0674(93)90027-N  0.534
1993 Doherty P, Singh A, Rimon G, Bolsover SR, Walsh FS. Thy-1 antibody-triggered neurite outgrowth requires an influx of calcium into neurons via N- and L-type calcium channels. The Journal of Cell Biology. 122: 181-9. PMID 8100230 DOI: 10.1083/Jcb.122.1.181  0.502
1993 Tomaselli KJ, Doherty P, Emmett CJ, Damsky CH, Walsh FS, Reichardt LF. Expression of beta 1 integrins in sensory neurons of the dorsal root ganglion and their functions in neurite outgrowth on two laminin isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4880-8. PMID 7693896 DOI: 10.1523/Jneurosci.13-11-04880.1993  0.519
1992 Doherty P, Ashton SV, Skaper SD, Leon A, Walsh FS. Ganglioside modulation of neural cell adhesion molecule and N-cadherin-dependent neurite outgrowth. The Journal of Cell Biology. 117: 1093-9. PMID 1577868 DOI: 10.1083/Jcb.117.5.1093  0.502
1992 Doherty P, Moolenaar CE, Ashton SV, Michalides RJ, Walsh FS. The VASE exon downregulates the neurite growth-promoting activity of NCAM 140. Nature. 356: 791-3. PMID 1574117 DOI: 10.1038/356791A0  0.502
1992 Doherty P, Rimon G, Mann DA, Walsh FS. Alternative splicing of the cytoplasmic domain of neural cell adhesion molecule alters its ability to act as a substrate for neurite outgrowth. Journal of Neurochemistry. 58: 2338-41. PMID 1573411 DOI: 10.1111/J.1471-4159.1992.Tb10984.X  0.502
1992 Williams EJ, Doherty P, Turner G, Reid RA, Hemperly JJ, Walsh FS. Calcium influx into neurons can solely account for cell contact-dependent neurite outgrowth stimulated by transfected L1. The Journal of Cell Biology. 119: 883-92. PMID 1429842 DOI: 10.1083/Jcb.119.4.883  0.564
1992 Doherty P, Walsh FS. Cell adhesion molecules, second messengers and axonal growth. Current Opinion in Neurobiology. 2: 595-601. PMID 1422115 DOI: 10.1016/0959-4388(92)90024-F  0.559
1992 Walsh FS, Furness J, Moore SE, Ashton S, Doherty P. Use of the neural cell adhesion molecule VASE exon by neurons is associated with a specific down-regulation of neural cell adhesion molecule-dependent neurite outgrowth in the developing cerebellum and hippocampus. Journal of Neurochemistry. 59: 1959-62. PMID 1402933 DOI: 10.1111/J.1471-4159.1992.Tb11033.X  0.502
1992 Saffell JL, Ashton SV, Walsh FS, Doherty P. The changing role of NCAM as a neurite outgrowth-promoting molecule during development. Biochemical Society Transactions. 20: 410-2. PMID 1397639 DOI: 10.1042/Bst0200410  0.502
1992 Saffell JL, Walsh FS, Doherty P. Direct activation of second messenger pathways mimics cell adhesion molecule-dependent neurite outgrowth. The Journal of Cell Biology. 118: 663-70. PMID 1379246 DOI: 10.1083/Jcb.118.3.663  0.502
1992 Walsh FS, Doherty P. Second messengers underlying cell-contact-dependent axonal growth stimulated by transfected N-CAM, N-cadherin, or L1. Cold Spring Harbor Symposia On Quantitative Biology. 57: 431-40. PMID 1339679 DOI: 10.1101/SQB.1992.057.01.048  0.498
1992 Doherty P, Walsh FS. Letter to the glyco-forum: 'is n-cam a 'non'-cell adhesion molecule?'-reply Glycobiology. 2: 1-2. DOI: 10.1093/glycob/2.1.1  0.472
1992 Doherty P, Walsh FS. Cell adhesion molecules, second messengers and axonal growth Current Biology. 2: 544. DOI: 10.1016/0960-9822(92)90025-6  0.502
1991 Doherty P, Rowett LH, Moore SE, Mann DA, Walsh FS. Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. Neuron. 6: 247-58. PMID 1993122 DOI: 10.1016/0896-6273(91)90360-C  0.502
1991 Walsh FS, Cronin M, Koblar S, Doherty P, Winer J, Leon A, Hughes RA. Association between glycoconjugate antibodies and Campylobacter infection in patients with Guillain-Barré syndrome. Journal of Neuroimmunology. 34: 43-51. PMID 1894733 DOI: 10.1016/0165-5728(91)90097-Q  0.502
1991 Koblar SA, Gregson NA, Hughes RA, Doherty P, Walsh FS. Campylobacter neuropathy. Neurology. 41: 1327-8. PMID 1866033  0.441
1991 Walsh FS, Doherty P. Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system. Cell Biology International Reports. 15: 1151-66. PMID 1838307 DOI: 10.1016/0309-1651(91)90061-M  0.533
1991 Doherty P, Walsh FS. The contrasting roles of N-CAM and N-cadherin as neurite outgrowth-promoting molecules. Journal of Cell Science. Supplement. 15: 13-21. PMID 1824104 DOI: 10.1242/Jcs.1991.Supplement_15.3  0.561
1991 Doherty P, Ashton SV, Moore SE, Walsh FS. Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels. Cell. 67: 21-33. PMID 1680564 DOI: 10.1016/0092-8674(91)90569-K  0.502
1991 Walsh FS, Doherty P. Structure and function of the gene for neural cell adhesion molecule Seminars in Neuroscience. 3: 271-284. DOI: 10.1016/1044-5765(91)90045-P  0.545
1990 Doherty P, Cohen J, Walsh FS. Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid. Neuron. 5: 209-19. PMID 2200449 DOI: 10.1016/0896-6273(90)90310-C  0.571
1990 Doherty P, Fruns M, Seaton P, Dickson G, Barton CH, Sears TA, Walsh FS. A threshold effect of the major isoforms of NCAM on neurite outgrowth. Nature. 343: 464-6. PMID 2153939 DOI: 10.1038/343464A0  0.502
1989 Doherty P, Barton CH, Dickson G, Seaton P, Rowett LH, Moore SE, Gower HJ, Walsh FS. Neuronal process outgrowth of human sensory neurons on monolayers of cells transfected with cDNAs for five human N-CAM isoforms. The Journal of Cell Biology. 109: 789-98. PMID 2760112 DOI: 10.1083/Jcb.109.2.789  0.502
1989 Doherty P, Walsh FS. Neurite guidance molecules. Current Opinion in Cell Biology. 1: 1102-6. PMID 2576858 DOI: 10.1016/S0955-0674(89)80057-2  0.515
1989 Mann DA, Doherty P, Walsh FS. Increased intracellular cyclic AMP differentially modulates nerve growth factor induction of three neuronal recognition molecules involved in neurite outgrowth. Journal of Neurochemistry. 53: 1581-8. PMID 2571678 DOI: 10.1111/J.1471-4159.1989.Tb08555.X  0.502
1989 Doherty P, Walsh FS. K-252a specifically inhibits the survival and morphological differentiation of NGF-dependent neurons in primary cultures of human dorsal root ganglia. Neuroscience Letters. 96: 1-6. PMID 2494608 DOI: 10.1016/0304-3940(89)90233-4  0.547
1988 Doherty P, Robinson E, Walsh FS. Analysis of PC12 cell adhesion to muscle and non-muscle cells and components of the extracellular matrix. Experimental Cell Research. 179: 233-42. PMID 3169142 DOI: 10.1016/0014-4827(88)90362-X  0.502
1988 Doherty P, Mann DA, Walsh FS. Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures. The Journal of Cell Biology. 107: 333-40. PMID 2899083 DOI: 10.1083/Jcb.107.1.333  0.502
1988 Doherty P, Seaton P, Flanigan TP, Walsh FS. Factors controlling the expression of the NGF receptor in PC12 cells. Neuroscience Letters. 92: 222-7. PMID 2847094 DOI: 10.1016/0304-3940(88)90065-1  0.502
1987 Doherty P, Walsh FS. Ganglioside GM1 antibodies and B-cholera toxin bind specifically to embryonic chick dorsal root ganglion neurons but do not modulate neurite regeneration. Journal of Neurochemistry. 48: 1237-44. PMID 3819728 DOI: 10.1111/J.1471-4159.1987.Tb05652.X  0.553
1987 Doherty P, Walsh FS. Control of Thy-1 glycoprotein expression in cultures of PC12 cells. Journal of Neurochemistry. 49: 610-6. PMID 2885399 DOI: 10.1111/J.1471-4159.1987.Tb02907.X  0.543
1987 Doherty P, Mann DA, Walsh FS. Cholera toxin and dibutyryl cyclic AMP inhibit the expression of neurofilament protein induced by nerve growth factor in cultures of naive and primed PC12 cells. Journal of Neurochemistry. 49: 1676-87. PMID 2824694 DOI: 10.1111/J.1471-4159.1987.Tb02425.X  0.502
1987 Prentice HM, Moore SE, Dickson JG, Doherty P, Walsh FS. Nerve growth factor-induced changes in neural cell adhesion molecule (N-CAM) in PC12 cells. The Embo Journal. 6: 1859-1863. DOI: 10.1002/J.1460-2075.1987.Tb02444.X  0.502
1986 Doherty P, Dickson JG, Flanigan TP, Kennedy PG, Walsh FS. Effects of amyotrophic lateral sclerosis serum on cultured chick spinal neurons. Neurology. 36: 1330-4. PMID 3762938 DOI: 10.1212/Wnl.36.10.1330  0.534
1986 Doherty P, Dickson JG, Flanigan TP, Walsh FS. Human skeletal muscle cells synthesise a neuronotrophic factor reactive with spinal neurons. Journal of Neurochemistry. 46: 133-9. PMID 3510008 DOI: 10.1111/J.1471-4159.1986.Tb12935.X  0.556
1985 Doherty P, Dickson JG, Flanigan TP, Leon A, Toffano G, Walsh FS. Molecular specificity of ganglioside effects on neurite regeneration of sensory neurons in vitro. Neuroscience Letters. 62: 193-8. PMID 3937073 DOI: 10.1016/0304-3940(85)90354-4  0.554
1985 Doherty P, Dickson JG, Flanigan TP, Walsh FS. Ganglioside GM1 does not initiate, but enhances neurite regeneration of nerve growth factor-dependent sensory neurones. Journal of Neurochemistry. 44: 1259-65. PMID 3919160 DOI: 10.1111/J.1471-4159.1985.Tb08752.X  0.55
1985 Doherty P, Dickson J, Flanigan T, Walsh F. GM1 Effects on nerve growth factor dependent differentiation of chicken dorsal root neurons in vitro International Journal of Developmental Neuroscience. 3: 458-458. DOI: 10.1016/0736-5748(85)90186-8  0.502
1984 Doherty P, Dickson JG, Flanigan TP, Walsh FS. The effect of nerve growth factor and its antibodies on neurofilament protein expression in primary cultures of sensory and spinal neurons. Neuroscience Letters. 51: 55-60. PMID 6440067 DOI: 10.1016/0304-3940(84)90262-3  0.532
1984 Doherty P, Dickson JG, Flanigan TP, Walsh FS. Quantitative evaluation of neurite outgrowth in cultures of human foetal brain and dorsal root ganglion cells using an enzyme-linked immunoadsorbent assay for human neurofilament protein. Journal of Neurochemistry. 42: 1116-22. PMID 6421998 DOI: 10.1111/J.1471-4159.1984.Tb12718.X  0.544
1984 DOHERTY P, DICKSON JG, WALSH FS. An enzyme-linked immuno-adsorbent assay for the quantification of neurofilament protein levels in cell cultures initiated from human foetal nervous tissue Biochemical Society Transactions. 12: 1120-1121. DOI: 10.1042/Bst0121120  0.502
1983 Dickson JG, Flanigan TP, Kemshead JT, Doherty P, Walsh FS. Identification of cell-surface antigens present exclusively on a sub-population of astrocytes in human foetal brain cultures. Journal of Neuroimmunology. 5: 111-23. PMID 6352739 DOI: 10.1016/0165-5728(83)90002-4  0.526
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