Stephen Watson - Publications

Affiliations: 
University of Notre Dame, Notre Dame, IN, United States 
Area:
Philosophy

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Buka RJ, Montague SJ, Moran LA, Martin EM, Slater A, Watson SP, Nicolson PLR. PF4 activates the c-Mpl-Jak2 pathway in platelets. Blood. PMID 37883794 DOI: 10.1182/blood.2023020872  0.323
2021 Martin EM, Zuidscherwoude M, Morán LA, Di Y, García A, Watson SP. The structure of CLEC-2: mechanisms of dimerization and higher-order clustering. Platelets. 1-11. PMID 33819136 DOI: 10.1080/09537104.2021.1906407  0.312
2020 Perrella G, Huang J, Provenzale I, Swieringa F, Heubel-Moenen FCJI, Farndale RW, Roest M, van der Meijden PEJ, Thomas M, Ariëns RAS, Jandrot-Perrus M, Watson SP, Heemskerk JWM. Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314641. PMID 33267658 DOI: 10.1161/ATVBAHA.120.314641  0.321
2020 Vögtle T, Baig AA, Volz J, Duchow TB, Pleines I, Dütting S, Nitschke L, Watson SP, Nieswandt B. Critical redundant functions of the adapters Grb2 and Gads in platelet (hem)ITAM signaling in mice. Platelets. 1-11. PMID 31948362 DOI: 10.1080/09537104.2019.1709633  0.314
2019 Onselaer MB, Nagy M, Pallini C, Pike JA, Perrella G, Quintanilla LG, Eble JA, Poulter NS, Heemskerk JWM, Watson SP. Comparison of the GPVI inhibitors losartan and honokiol. Platelets. 1-11. PMID 30849265 DOI: 10.1080/09537104.2019.1585526  0.316
2019 Kardeby C, Fälker K, Haining EJ, Criel M, Lindkvist M, Barroso R, Påhlsson P, Ljungberg LU, Tengdelius M, Rainger GE, Watson S, Eble JA, Hoylaerts MF, Emsley J, Konradsson P, ... Watson SP, et al. Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα. Blood Advances. 3: 275-287. PMID 30700416 DOI: 10.1182/bloodadvances.2018024950  0.354
2018 Hardy AT, Palma-Barqueros V, Watson SK, Malcor JD, Eble JA, Gardiner EE, Blanco JE, Guijarro-Campillo R, Delgado JL, Lozano ML, Teruel-Montoya R, Vicente V, Watson SP, Rivera J, Ferrer-Marín F. Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia. Thrombosis and Haemostasis. PMID 29695020 DOI: 10.1055/s-0038-1646924  0.338
2018 Sheriff L, Alanazi A, Ward LSC, Ward C, Munir H, Rayes J, Alassiri M, Watson SP, Newsome PN, Ed Rainger G, Kalia N, Frampton J, McGettrick HM, Nash GB. Origin-specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence their Behaviour After Infusion. Stem Cells (Dayton, Ohio). PMID 29488279 DOI: 10.1002/stem.2811  0.306
2018 Mangin PH, Onselaer MB, Receveur N, Le Lay N, Hardy AT, Wilson C, Sanchez X, Loyau S, Dupuis A, Babar AK, Miller JL, Philippou H, Hughes CE, Herr AB, Ariëns RA, ... ... Watson SP, et al. Immobilized fibrinogen activates human platelets through GPVI. Haematologica. PMID 29472360 DOI: 10.3324/Haematol.2017.182972  0.32
2018 Ilkan Z, Watson S, Watson SP, Mahaut-Smith MP. P2X1 Receptors Amplify FcγRIIa-Induced Ca2+ Increases and Functional Responses in Human Platelets. Thrombosis and Haemostasis. 118: 369-380. PMID 29443373 DOI: 10.1160/TH17-07-0530  0.303
2018 Ghuman H, Shepherd-Roberts A, Watson S, Zuidscherwoude M, Watson SP, Voelz K. Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA. Platelets. 1-8. PMID 29297721 DOI: 10.1080/09537104.2017.1420152  0.318
2017 Onselaer MB, Hardy AT, Wilson C, Sanchez X, Babar AK, Miller JLC, Watson CN, Watson SK, Bonna A, Philippou H, Herr AB, Mezzano D, Ariëns RAS, Watson SP. Fibrin and D-dimer bind to monomeric GPVI. Blood Advances. 1: 1495-1504. PMID 29296791 DOI: 10.1182/Bloodadvances.2017007732  0.318
2017 Lombard SE, Pollitt AY, Hughes CE, Di Y, Mckinnon T, O'callaghan CA, Watson SP. Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: A novel mechanism of haemostasis. Platelets. 1-7. PMID 29090616 DOI: 10.1080/09537104.2017.1356919  0.324
2017 Sevivas T, Bastida JM, Paul DS, Caparros E, Palma-Barqueros V, Coucelo M, Marques D, Ferrer-Marín F, González-Porras JR, Vicente V, Hernández-Rivas JM, Watson SP, Lozano ML, Bergmeier W, Rivera J. Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis. Platelets. 1-4. PMID 28762304 DOI: 10.1080/09537104.2017.1336214  0.316
2017 Smith CW, Thomas SG, Raslan Z, Patel P, Byrne M, Lordkipanidzé M, Bem D, Meyaard L, Senis YA, Watson SP, Mazharian A. Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28336561 DOI: 10.1161/ATVBAHA.117.309253  0.324
2016 Haining EJ, Matthews AL, Noy PJ, Romanska HM, Harris HJ, Pike J, Morowski M, Gavin RL, Yang J, Milhiet PE, Berditchevski F, Nieswandt B, Poulter NS, Watson SP, Tomlinson MG. Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation. Platelets. 1-14. PMID 28032533 DOI: 10.1080/09537104.2016.1254175  0.308
2016 Thomas SG, Poulter NS, Bem D, Finney B, Machesky LM, Watson SP. The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation. Platelets. 1-8. PMID 27778524 DOI: 10.1080/09537104.2016.1235688  0.308
2016 Watson CN, Kerrigan SW, Cox D, Henderson IR, Watson SP, Arman M. Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3. Platelets. 1-6. PMID 27025455 DOI: 10.3109/09537104.2016.1148129  0.316
2015 Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP. Fibrin activates GPVI in human and mouse platelets. Blood. 126: 1601-8. PMID 26282541 DOI: 10.1182/blood-2015-04-641654  0.343
2015 Sánchez Guiu IM, Martínez-Martínez I, Martínez C, Navarro-Fernández J, García-Candel F, Ferrer-Marín F, Vicente V, Watson SP, Andrews RK, Gardiner EE, Lozano ML, Rivera J. An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets. Thrombosis and Haemostasis. 114. PMID 25994029 DOI: 10.1160/TH14-11-0945  0.315
2015 Lorenz V, Stegner D, Stritt S, Vögtle T, Kiefer F, Witke W, Schymeinsky J, Watson SP, Walzog B, Nieswandt B. Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization. Blood. 125: 4069-77. PMID 25795918 DOI: 10.1182/blood-2014-11-611905  0.324
2015 Moroi AJ, Watson SP. Impact of the PI3-kinase/Akt pathway on ITAM and hemITAM receptors: haemostasis, platelet activation and antithrombotic therapy. Biochemical Pharmacology. 94: 186-94. PMID 25698506 DOI: 10.1016/j.bcp.2015.02.004  0.307
2015 Navarro-Núñez L, Pollitt AY, Lowe K, Latif A, Nash GB, Watson SP. Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling. Thrombosis and Haemostasis. 113: 1109-20. PMID 25694214 DOI: 10.1160/TH14-09-0762  0.329
2015 Cherpokova D, Bender M, Morowski M, Kraft P, Schuhmann MK, Akbar SM, Sultan CS, Hughes CE, Kleinschnitz C, Stoll G, Dragone LL, Watson SP, Tomlinson MG, Nieswandt B. SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice. Blood. 125: 185-94. PMID 25301707 DOI: 10.1182/blood-2014-06-580597  0.315
2014 Gitz E, Pollitt AY, Gitz-Francois JJ, Alshehri O, Mori J, Montague S, Nash GB, Douglas MR, Gardiner EE, Andrews RK, Buckley CD, Harrison P, Watson SP. CLEC-2 expression is maintained on activated platelets and on platelet microparticles. Blood. 124: 2262-70. PMID 25150298 DOI: 10.1182/Blood-2014-05-572818  0.334
2014 Arman M, Krauel K, Tilley DO, Weber C, Cox D, Greinacher A, Kerrigan SW, Watson SP. Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4. Blood. 123: 3166-74. PMID 24642751 DOI: 10.1182/blood-2013-11-540526  0.333
2014 Watson SP, Lowe K, Finney BA. Platelets in lymph vessel development and integrity. Advances in Anatomy, Embryology, and Cell Biology. 214: 93-105. PMID 24276889 DOI: 10.1007/978-3-7091-1646-3_8  0.325
2014 Dütting S, Vögtle T, Morowski M, Schiessl S, Schäfer CM, Watson SK, Hughes CE, Ackermann JA, Radtke D, Hermanns HM, Watson SP, Nitschke L, Nieswandt B. Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets. Circulation Research. 114: 444-53. PMID 24265393 DOI: 10.1161/CIRCRESAHA.114.302670  0.301
2013 Manne BK, Getz TM, Hughes CE, Alshehri O, Dangelmaier C, Naik UP, Watson SP, Kunapuli SP. Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2). The Journal of Biological Chemistry. 288: 7717-26. PMID 23341451 DOI: 10.1074/Jbc.M112.424473  0.352
2012 Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA. Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function. Science Signaling. 5: ra78. PMID 23112346 DOI: 10.1126/scisignal.2002936  0.305
2012 Manne B, Getz TM, Hughes C, Dangelmaier CT, Watson SP, Kunapuli SP. Fucoidan Is a Novel Platelet Agonist for CLEC-2 Receptor Blood. 120: 94-94. DOI: 10.1182/Blood.V120.21.94.94  0.344
2011 Unsworth AJ, Smith H, Gissen P, Watson SP, Pears CJ. Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+ Journal of Biological Chemistry. 286: 21073-21082. PMID 21489985 DOI: 10.1074/jbc.M110.187138  0.306
2011 Brazón J, Hughes CE, Mori J, Sevcik C, D'suze G, Watson SP. Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway. Platelets. 22: 165-72. PMID 21322750 DOI: 10.3109/09537104.2010.544343  0.333
2010 Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH. A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function. The Journal of Experimental Medicine. 207: 1967-79. PMID 20713593 DOI: 10.1084/Jem.20100222  0.349
2010 Mazharian A, Thomas SG, Dhanjal TS, Buckley CD, Watson SP. Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis. Blood. 116: 793-800. PMID 20457868 DOI: 10.1182/blood-2010-03-275990  0.318
2009 Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP. The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis. Blood. 113: 4942-54. PMID 19246339 DOI: 10.1182/Blood-2008-08-174318  0.319
2009 Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW. PKCalpha regulates platelet granule secretion and thrombus formation in mice. The Journal of Clinical Investigation. 119: 399-407. PMID 19147982 DOI: 10.1172/Jci34665  0.313
2009 Protty MB, Watkins NA, Colombo D, Thomas SG, Heath VL, Herbert JM, Bicknell R, Senis YA, Ashman LK, Berditchevski F, Ouwehand WH, Watson SP, Tomlinson MG. Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. The Biochemical Journal. 417: 391-400. PMID 18795891 DOI: 10.1042/BJ20081126  0.304
2009 Falet H, Pollitt AY, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH. Filamin A Deficiency in Platelets Reveals Functional Impairment in ITAM-Based Signaling. Blood. 114: 769-769. DOI: 10.1182/Blood.V114.22.769.769  0.334
2009 Ghevaert CJ, Li J, Severin S, Auger J, Watson S, Green AR. Physiological Levels of Jak2 V617F Result in Enhanced Megakaryocyte Differentiation, Proplatelet Formation and Platelet Reactivity. Blood. 114: 226-226. DOI: 10.1182/BLOOD.V114.22.226.226  0.301
2008 Mori J, Pearce AC, Spalton JC, Grygielska B, Eble JA, Tomlinson MG, Senis YA, Watson SP. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2. The Journal of Biological Chemistry. 283: 35419-27. PMID 18955485 DOI: 10.1074/jbc.M806895200  0.321
2008 Hughes CE, Auger JM, McGlade J, Eble JA, Pearce AC, Watson SP. Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2. Journal of Thrombosis and Haemostasis : Jth. 6: 2152-9. PMID 18826392 DOI: 10.1111/j.1538-7836.2008.03166.x  0.326
2007 Munnix IC, Kuijpers MJ, Auger J, Thomassen CM, Panizzi P, van Zandvoort MA, Rosing J, Bock PE, Watson SP, Heemskerk JW. Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2484-90. PMID 17761939 DOI: 10.1161/Atvbaha.107.151100  0.314
2007 Dawood BB, Wilde J, Watson SP. Reference curves for aggregation and ATP secretion to aid diagnose of platelet-based bleeding disorders: Effect of inhibition of ADP and thromboxane A2 pathways Platelets. 18: 329-345. PMID 17654303 DOI: 10.1080/09537100601024111  0.308
2007 Calaminus SD, Auger JM, McCarty OJ, Wakelam MJ, Machesky LM, Watson SP. MyosinIIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability. Journal of Thrombosis and Haemostasis : Jth. 5: 2136-45. PMID 17645784 DOI: 10.1111/J.1538-7836.2007.02696.X  0.3
2007 Rabie T, Varga-Szabo D, Bender M, Pozgaj R, Lanza F, Saito T, Watson SP, Nieswandt B. Diverging signaling events control the pathway of GPVI down-regulation in vivo. Blood. 110: 529-35. PMID 17374738 DOI: 10.1182/blood-2006-11-058107  0.3
2007 Dhanjal TS, Ross EA, Auger JM, McCarty OJ, Hughes CE, Senis YA, Buckley CD, Watson SP. Minimal regulation of platelet activity by PECAM-1. Platelets. 18: 56-67. PMID 17365855 DOI: 10.1080/09537100600881396  0.355
2007 Hughan SC, Hughes CE, McCarty OJ, Schweighoffer E, Soultanova I, Ware J, Tybulewicz VL, Watson SP. GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 422-9. PMID 17110603 DOI: 10.1161/01.ATV.0000252826.96134.21  0.306
2007 Hughan SC, Watson SP. Differential regulation of adapter proteins Dok2 and Dok1 in platelets, leading to an association of Dok2 with integrin αIIbβ3 Journal of Thrombosis and Haemostasis. 5: 387-394. PMID 17092301 DOI: 10.1111/j.1538-7836.2007.02307.x  0.31
2007 Pearce AC, McCarty OJ, Calaminus SD, Vigorito E, Turner M, Watson SP. Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3. The Biochemical Journal. 401: 753-61. PMID 17054426 DOI: 10.1042/Bj20061508  0.307
2007 García A, Senis YA, Antrobus R, Hughes CE, Hughan SC, Watson SP, Zitzmann N. IDENTIFICATION OF NOVEL TYROSINE PHOSPHORYLATED SIGNALLING PROTEINS FOLLOWING αIIbβ3-MEDIATED PLATELET SPREADING: INVOLVEMENT OF THE IMMUNOGLOBULIN SUPERFAMILY MEMBERS G6B-B AND G6F, AND THE NOVEL PLATELET ADAPTER DOK-3 Journal of Thrombosis and Haemostasis. 5. DOI: 10.1111/J.1538-7836.2007.Tb01194.X  0.308
2006 García A, Senis YA, Antrobus R, Hughes CE, Dwek RA, Watson SP, Zitzmann N. A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter. Proteomics. 6: 5332-43. PMID 16941570 DOI: 10.1002/Pmic.200600299  0.324
2006 McCarty OJ, Calaminus SD, Berndt MC, Machesky LM, Watson SP. von Willebrand factor mediates platelet spreading through glycoprotein Ib and αIIbβ3 in the presence of botrocetin and ristocetin, respectively Journal of Thrombosis and Haemostasis. 4: 1367-1378. PMID 16706984 DOI: 10.1111/J.1538-7836.2006.01966.X  0.34
2006 Inoue O, Suzuki-Inoue K, McCarty OJ, Moroi M, Ruggeri ZM, Kunicki TJ, Ozaki Y, Watson SP. Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. Blood. 107: 1405-12. PMID 16219796 DOI: 10.1182/blood-2005-06-2406  0.34
2006 Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, ... ... Watson SP, et al. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2. Blood. 107: 542-9. PMID 16174766 DOI: 10.1182/Blood-2005-05-1994  0.345
2005 Yi Q, Suzuki-Inoue K, Asazuma N, Inoue O, Watson SP, Ozaki Y. Docking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation. Biochemical and Biophysical Research Communications. 337: 446-51. PMID 16198316 DOI: 10.1016/J.BBRC.2005.09.074  0.337
2005 McCarty OJ, Larson MK, Auger JM, Kalia N, Atkinson BT, Pearce AC, Ruf S, Henderson RB, Tybulewicz VL, Machesky LM, Watson SP. Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow. The Journal of Biological Chemistry. 280: 39474-84. PMID 16195235 DOI: 10.1074/jbc.M504672200  0.302
2005 Watson SP, Auger JM, McCarty OJ, Pearce AC. GPVI and integrin alphaIIb beta3 signaling in platelets. Journal of Thrombosis and Haemostasis : Jth. 3: 1752-62. PMID 16102042 DOI: 10.1111/J.1538-7836.2005.01429.X  0.309
2005 Senis YA, Atkinson BT, Pearce AC, Wonerow P, Auger JM, Okkenhaug K, Pearce W, Vigorito E, Vanhaesebroeck B, Turner M, Watson SP. Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets. Platelets. 16: 191-202. PMID 16011964 DOI: 10.1080/09537100400016711  0.321
2005 Auger JM, Kuijpers MJ, Senis YA, Watson SP, Heemskerk JW. Adhesion of human and mouse platelets to collagen under shear: a unifying model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 825-7. PMID 15758040 DOI: 10.1096/fj.04-1940fje  0.345
2005 Hughan SC, Senis Y, Best D, Thomas A, Frampton J, Vyas P, Watson SP. Selective impairment of platelet activation to collagen in the absence of GATA1. Blood. 105: 4369-76. PMID 15701726 DOI: 10.1182/BLOOD-2004-10-4098  0.342
2004 Pearce AC, Senis YA, Billadeau DD, Turner M, Watson SP, Vigorito E. Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. The Journal of Biological Chemistry. 279: 53955-62. PMID 15456756 DOI: 10.1074/Jbc.M410355200  0.329
2004 McCarty OJ, Zhao Y, Andrew N, Machesky LM, Staunton D, Frampton J, Watson SP. Evaluation of the role of platelet integrins in fibronectin-dependent spreading and adhesion. Journal of Thrombosis and Haemostasis : Jth. 2: 1823-33. PMID 15456495 DOI: 10.1111/j.1538-7836.2004.00925.x  0.304
2004 Jarvis GE, Best D, Watson SP. Differential roles of integrins α2β1 and αIIbβ3 collagen and CRP-induced platelet activation Platelets. 15: 303-313. PMID 15370101 DOI: 10.1080/09537100410001710254  0.306
2004 Jarvis GE, Best D, Watson SP. Glycoprotein VI/Fc receptor γ chain-independent tyrosine phosphorylation and activation of murine platelets by collagen Biochemical Journal. 383: 581-588. PMID 15283702 DOI: 10.1042/BJ20040654  0.31
2004 Pearce AC, Wonerow P, Marshall SJ, Frampton J, Gartner TK, Watson SP. The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIa. The Biochemical Journal. 378: 193-9. PMID 14558887 DOI: 10.1042/Bj20031298  0.343
2003 Auger JM, Best D, Snell DC, Wilde J, Watson SP. C-Cbl negatively regulates platelet activation by glycoprotein VI Journal of Thrombosis and Haemostasis. 1: 2419-2426. PMID 14629478 DOI: 10.1046/j.1538-7836.2003.00464.x  0.313
2003 Atkinson BT, Ellmeier W, Watson SP. Tec regulates platelet activation by GPVI in the absence of Btk Blood. 102: 3592-3599. PMID 12842985 DOI: 10.1182/blood-2003-04-1142  0.348
2003 Wonerow P, Pearce AC, Vaux DJ, Watson SP. A critical role for phospholipase Cγ2 in αIIbβ 3-mediated platelet spreading Journal of Biological Chemistry. 278: 37520-37529. PMID 12832411 DOI: 10.1074/jbc.M305077200  0.337
2003 Suzuki-Inoue K, Inoue O, Frampton J, Watson SP. Murine GPVI stimulates weak integrin activation in PLCγ2 -/- platelets: Involvement of PLCγ1 and PI3-kinase Blood. 102: 1367-1373. PMID 12730118 DOI: 10.1182/blood-2003-01-0029  0.323
2003 Nieswandt B, Watson SP. Platelet-collagen interaction: Is GPVI the central receptor? Blood. 102: 449-461. PMID 12649139 DOI: 10.1182/blood-2002-12-3882  0.324
2003 Inoue O, Suzuki-Inoue K, Dean WL, Frampton J, Watson SP. Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2. The Journal of Cell Biology. 160: 769-80. PMID 12615912 DOI: 10.1083/jcb.200208043  0.335
2003 Jarvis GE, Atkinson BT, Frampton J, Watson SP. Thrombin-induced conversion of fibrinogen to fibrin results in rapid platelet trapping which is not dependent on platelet activation or GPIb British Journal of Pharmacology. 138: 574-583. PMID 12598411 DOI: 10.1038/sj.bjp.0705095  0.327
2002 Pearce AC, Wilde JI, Doody GM, Best D, Inoue O, Vigorito E, Tybulewicz VL, Turner M, Watson SP. Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood. 100: 3561-9. PMID 12411320 DOI: 10.1182/Blood.V100.10.3561  0.364
2002 Snell DC, Schulte V, Jarvis GE, Arase K, Sakurai D, Saito T, Watson SP, Nieswandt B. Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands. The Biochemical Journal. 368: 293-300. PMID 12117414 DOI: 10.1042/BJ20020335  0.31
2002 Wonerow P, Obergfell A, Wilde JI, Bobe R, Asazuma N, Brdička T, Leo A, Schraven B, Hořejší V, Shattil SJ, Watson SP. Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cγ2 regulation in platelets Biochemical Journal. 364: 755-765. PMID 12049640 DOI: 10.1042/BJ20020128  0.341
2002 Marshall SJ, Asazuma N, Best D, Wonerow P, Salmon G, Andrews RK, Watson SP. Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway. The Biochemical Journal. 361: 297-305. PMID 11772401 DOI: 10.1042/0264-6021:3610297  0.325
2001 Stafford MJ, Atkinson BT, Watson SP, Pears CJ. Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester Platelets. 12: 476-485. PMID 11798397 DOI: 10.1080/095371001317126374  0.321
2001 Tulasne D, Judd BA, Johansen M, Asazuma N, Best D, Brown EJ, Kahn M, Koretzky GA, Watson SP. C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination. Blood. 98: 3346-52. PMID 11719373 DOI: 10.1182/Blood.V98.12.3346  0.313
2001 Atkinson BT, Stafford MJ, Pears CJ, Watson SP. Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin European Journal of Biochemistry. 268: 5242-5248. PMID 11606185 DOI: 10.1046/j.0014-2956.2001.02448.x  0.337
2001 Andrews RK, Gardiner EE, Asazuma N, Berlanga O, Tulasne D, Nieswandt B, Smith AI, Berndt MC, Watson SP. A novel viper venom metalloproteinase, alborhagin, is an agonist at the platelet collagen receptor GPVI. The Journal of Biological Chemistry. 276: 28092-7. PMID 11344165 DOI: 10.1074/JBC.M011352200  0.351
2001 Best D, Pasquet S, Littlewood TJ, Brunskill SJ, Pallister CJ, Watson SP. Platelet activation via the collagen receptor GPVI is not altered in platelets from chronic myeloid leukaemia patients despite the presence of the constitutively phosphorylated adapter protein CrkL. British Journal of Haematology. 112: 609-15. PMID 11260061 DOI: 10.1046/j.1365-2141.2001.02624.x  0.34
2001 Schulte V, Snell D, Bergmeier W, Zirngibl H, Watson SP, Nieswandt B. Evidence for two distinct epitopes within collagen for activation of murine platelets. The Journal of Biological Chemistry. 276: 364-8. PMID 11036078 DOI: 10.1074/jbc.M007536200  0.335
2000 Asazuma N, Wilde JI, Berlanga O, Leduc M, Leo A, Schweighoffer E, Tybulewicz V, Bon C, Liu SK, McGlade CJ, Schraven B, Watson SP. Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin. Journal of Biological Chemistry. 275: 33427-33434. PMID 10942756 DOI: 10.1074/Jbc.M001439200  0.31
2000 Quek LS, Pasquet J, Hers I, Cornall R, Knight G, Barnes M, Hibbs ML, Dunn AR, Lowell CA, Watson SP. Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway Blood. 96: 4246-4253. DOI: 10.1182/Blood.V96.13.4246.H8004246_4246_4253  0.33
1999 Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP. LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. Molecular and Cellular Biology. 19: 8326-34. PMID 10567557 DOI: 10.1128/Mcb.19.12.8326  0.31
1999 Gross BS, Lee JR, Clements JL, Turner M, Tybulewicz VL, Findell PR, Koretzky GA, Watson SP. Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets. The Journal of Biological Chemistry. 274: 5963-71. PMID 10026222 DOI: 10.1074/Jbc.274.9.5963  0.311
1999 Gross BS, Wilde JI, Quek L, Chapel H, Nelson DL, Watson SP. Regulation and Function of WASp in Platelets by the Collagen Receptor, Glycoprotein VI Blood. 94: 4166-4176. DOI: 10.1182/BLOOD.V94.12.4166.424K36_4166_4176  0.344
1999 Watson S. Collagen Receptor Signaling in Platelets and Megakaryocytes Thrombosis and Haemostasis. 82: 365-376. DOI: 10.1055/S-0037-1615855  0.303
1999 ASSELIN J, KNIGHT CG, FARNDALE RW, BARNES MJ, WATSON SP. Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI Biochemical Journal. 339: 413-418. DOI: 10.1042/Bj3390413  0.322
1999 BRIDDON SJ, WATSON SP. Evidence for the involvement of p59fyn and p53/56lyn in collagen receptor signalling in human platelets Biochemical Journal. 338: 203-209. DOI: 10.1042/BJ3380203  0.306
1998 Quek LS, Bolen J, Watson SP. A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen Current Biology. 8: 1137-1140. PMID 9778529 DOI: 10.1016/S0960-9822(98)70471-3  0.355
1998 Watson SP, Gibbins J. Collagen receptor signalling in platelets extending the role of the ITAM Immunology Today. 19: 260-264. PMID 9639990 DOI: 10.1016/S0167-5699(98)01267-5  0.329
1997 Asselin J, Gibbins JM, Achison M, Lee YH, Morton LF, Farndale RW, Barnes MJ, Watson SP. A Collagen-Like Peptide Stimulates Tyrosine Phosphorylation of syk and Phospholipase Cγ2 in Platelets Independent of the Integrin α2β1 Blood. 89: 1235-1242. DOI: 10.1182/Blood.V89.4.1235  0.323
1996 Gibbins J, Asselin J, Farndale R, Barnes M, Law CL, Watson SP. Tyrosine phosphorylation of the Fc receptor γ-chain in collagen- stimulated platelets Journal of Biological Chemistry. 271: 18095-18099. PMID 8663460 DOI: 10.1074/Jbc.271.30.18095  0.321
1996 Rodriguez-Linares B, Watson SP. Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation Biochemical Journal. 316: 93-98. PMID 8645238 DOI: 10.1042/BJ3160093  0.329
1995 Yanaga F, Asselin J, Schieven GL, Watson SP. Phenylarsine oxide inhibits tyrosine phosphorylation of phospholipase Cγ2 in human platelets and phospholipase Cγ1 in NIH-3T3 fibroblasts Febs Letters. 368: 377-380. PMID 7628642 DOI: 10.1016/0014-5793(95)00670-5  0.32
1994 Blake RA, Schieven GL, Watson SP. Collagen stimulates tyrosine phosphorylation of phospholipase C-γ2 but not phospholipase C-γ1 in human platelets Febs Letters. 353: 212-216. PMID 7523195 DOI: 10.1016/0014-5793(94)01037-4  0.31
1987 Polascik T, Godfrey PP, Watson SP. Neomycin cannot be used as a selective inhibitor of inositol phospholipid hydrolysis in intact or semi-permeabilized human platelets. Aminoglycosides activate semi-permeabilized platelets Biochemical Journal. 243: 815-819. PMID 3663101 DOI: 10.1042/BJ2430815  0.302
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