Phil Barker - Publications

Affiliations: 
Montreal Neurological Institute, McGill University, Montréal, Québec, Canada 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Thomas RA, Ambalavanan A, Rouleau GA, Barker PA. Identification of genetic variants of LGI1 and RTN4R (NgR1) linked to schizophrenia that are defective in NgR1-LGI1 signaling. Molecular Genetics & Genomic Medicine. 4: 447-456. PMID 27468420 DOI: 10.1002/Mgg3.215  0.543
2016 Danelon V, Montroull LE, Unsain N, Barker PA, Mascó DH. Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes. Molecular and Cellular Neurosciences. PMID 27449758 DOI: 10.1016/J.Mcn.2016.07.002  0.769
2016 Gibon J, Unsain N, Gamache K, Thomas RA, De Leon A, Johnstone A, Nader K, Séguéla P, Barker PA. The X-linked inhibitor of apoptosis regulates long-term depression and learning rate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27189977 DOI: 10.1096/Fj.201600384R  0.752
2016 Gibon J, Barker PA, Séguéla P. Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex. Molecular Brain. 9: 23. PMID 26932787 DOI: 10.1186/S13041-016-0203-9  0.313
2015 Unsain N, Barker PA. New Views on the Misconstrued: Executioner Caspases and Their Diverse Non-apoptotic Roles. Neuron. 88: 461-74. PMID 26539888 DOI: 10.1016/J.Neuron.2015.08.029  0.733
2015 Cueva Vargas JL, Osswald IK, Unsain N, Aurousseau MR, Barker PA, Bowie D, Di Polo A. Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12088-102. PMID 26338321 DOI: 10.1523/Jneurosci.1273-15.2015  0.779
2015 Gibon J, Buckley SM, Unsain N, Kaartinen V, Séguéla P, Barker PA. proBDNF and p75NTR Control Excitability and Persistent Firing of Cortical Pyramidal Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9741-53. PMID 26134656 DOI: 10.1523/Jneurosci.4655-14.2015  0.745
2015 Choe KY, Han SY, Gaub P, Shell B, Voisin DL, Knapp BA, Barker PA, Brown CH, Cunningham JT, Bourque CW. High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons. Neuron. 85: 549-60. PMID 25619659 DOI: 10.1016/J.Neuron.2014.12.048  0.689
2015 Gibon J, Buckley SM, Unsain N, Kaartinen V, Séguéla P, Barker PA. proBDNF and p75NTR control excitability and persistent firing of cortical pyramidal neurons Journal of Neuroscience. 35: 9741-9753. DOI: 10.1523/JNEUROSCI.4655-14.2015  0.706
2014 Angelo MF, Aguirre A, Avilés Reyes RX, Villarreal A, Lukin J, Melendez M, Vanasco V, Barker P, Alvarez S, Epstein A, Jerusalinsky D, Ramos AJ. The proinflammatory RAGE/NF-κB pathway is involved in neuronal damage and reactive gliosis in a model of sleep apnea by intermittent hypoxia. Plos One. 9: e107901. PMID 25265561 DOI: 10.1371/Journal.Pone.0107901  0.332
2014 Unsain N, Heard KN, Higgins JM, Barker PA. Production and isolation of axons from sensory neurons for biochemical analysis using porous filters. Journal of Visualized Experiments : Jove. PMID 25046441 DOI: 10.3791/51795  0.755
2014 Villarreal A, Seoane R, González Torres A, Rosciszewski G, Angelo MF, Rossi A, Barker PA, Ramos AJ. S100B protein activates a RAGE-dependent autocrine loop in astrocytes: implications for its role in the propagation of reactive gliosis. Journal of Neurochemistry. PMID 24923428 DOI: 10.1111/Jnc.12790  0.307
2014 Ceni C, Unsain N, Zeinieh MP, Barker PA. Neurotrophins in the regulation of cellular survival and death. Handbook of Experimental Pharmacology. 220: 193-221. PMID 24668474 DOI: 10.1007/978-3-642-45106-5_8  0.745
2013 Unsain N, Higgins JM, Parker KN, Johnstone AD, Barker PA. XIAP regulates caspase activity in degenerating axons. Cell Reports. 4: 751-63. PMID 23954782 DOI: 10.1016/J.Celrep.2013.07.015  0.772
2013 Ruan W, Unsain N, Desbarats J, Fon EA, Barker PA. Wengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development. Plos One. 8: e60091. PMID 23544124 DOI: 10.1371/Journal.Pone.0060091  0.702
2013 Wilson AM, Morquette B, Abdouh M, Unsain N, Barker PA, Feinstein E, Bernier G, Di Polo A. ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2205-16. PMID 23365256 DOI: 10.1523/Jneurosci.2635-12.2013  0.735
2011 Kommaddi RP, Thomas R, Ceni C, Daigneault K, Barker PA. Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2061-70. PMID 21411748 DOI: 10.1096/Fj.10-173740  0.641
2010 Ceni C, Kommaddi RP, Thomas R, Vereker E, Liu X, McPherson PS, Ritter B, Barker PA. The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. Journal of Cell Science. 123: 2299-307. PMID 20530577 DOI: 10.1242/Jcs.062612  0.643
2010 Xu B, Goldman JS, Rymar VV, Forget C, Lo PS, Bull SJ, Vereker E, Barker PA, Trudeau LE, Sadikot AF, Kennedy TE. Critical roles for the netrin receptor deleted in colorectal cancer in dopaminergic neuronal precursor migration, axon guidance, and axon arborization. Neuroscience. 169: 932-49. PMID 20493932 DOI: 10.1016/J.Neuroscience.2010.05.025  0.575
2010 Thomas R, Favell K, Morante-Redolat J, Pool M, Kent C, Wright M, Daignault K, Ferraro GB, Montcalm S, Durocher Y, Fournier A, Perez-Tur J, Barker PA. LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6607-12. PMID 20463223 DOI: 10.1523/Jneurosci.5147-09.2010  0.622
2010 Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA. ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3817-22. PMID 20133718 DOI: 10.1073/Pnas.0909276107  0.336
2009 Lebrun-Julien F, Duplan L, Pernet V, Osswald I, Sapieha P, Bourgeois P, Dickson K, Bowie D, Barker PA, Di Polo A. Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5536-45. PMID 19403821 DOI: 10.1523/Jneurosci.0831-09.2009  0.621
2009 Angelo MF, Aviles-Reyes RX, Villarreal A, Barker P, Reines AG, Ramos AJ. p75 NTR expression is induced in isolated neurons of the penumbra after ischemia by cortical devascularization. Journal of Neuroscience Research. 87: 1892-903. PMID 19156869 DOI: 10.1002/jnr.21993  0.322
2008 Bertrand MJ, Kenchappa RS, Andrieu D, Leclercq-Smekens M, Nguyen HN, Carter BD, Muscatelli F, Barker PA, De Backer O. NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death and Differentiation. 15: 1921-9. PMID 18772898 DOI: 10.1038/Cdd.2008.127  0.327
2008 Moore SW, Lai Wing Sun K, Xie F, Barker PA, Conti M, Kennedy TE. Soluble adenylyl cyclase is not required for axon guidance to netrin-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3920-4. PMID 18400890 DOI: 10.1523/Jneurosci.0547-08.2008  0.557
2008 Boutilier J, Ceni C, Pagdala PC, Forgie A, Neet KE, Barker PA. Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation. The Journal of Biological Chemistry. 283: 12709-16. PMID 18299325 DOI: 10.1074/Jbc.M710018200  0.322
2006 Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD. Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron. 50: 219-32. PMID 16630834 DOI: 10.1016/J.Neuron.2006.03.011  0.32
2004 Ormond J, Hislop J, Zhao Y, Webb N, Vaillaincourt F, Dyer JR, Ferraro G, Barker P, Martin KC, Sossin WS. ApTrkl, a Trk-like receptor, mediates serotonin- dependent ERK activation and long-term facilitation in Aplysia sensory neurons. Neuron. 44: 715-28. PMID 15541318 DOI: 10.1016/j.neuron.2004.11.001  0.313
2004 Becker EB, Howell J, Kodama Y, Barker PA, Bonni A. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8762-70. PMID 15470142 DOI: 10.1523/Jneurosci.2953-04.2004  0.342
2004 Florez-McClure ML, Linseman DA, Chu CT, Barker PA, Bouchard RJ, Le SS, Laessig TA, Heidenreich KA. The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4498-509. PMID 15140920 DOI: 10.1523/Jneurosci.5744-03.2004  0.367
2004 Bouchard JF, Moore SW, Tritsch NX, Roux PP, Shekarabi M, Barker PA, Kennedy TE. Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3040-50. PMID 15044543 DOI: 10.1523/Jneurosci.4934-03.2004  0.669
2002 Roux PP, Dorval G, Boudreau M, Angers-Loustau A, Morris SJ, Makkerh J, Barker PA. K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. The Journal of Biological Chemistry. 277: 49473-80. PMID 12388555 DOI: 10.1074/Jbc.M203428200  0.519
2002 Roux PP, Barker PA. Neurotrophin signaling through the p75 neurotrophin receptor. Progress in Neurobiology. 67: 203-33. PMID 12169297 DOI: 10.1016/S0301-0082(02)00016-3  0.554
2001 Roux PP, Bhakar AL, Kennedy TE, Barker PA. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. The Journal of Biological Chemistry. 276: 23097-104. PMID 11312266 DOI: 10.1074/Jbc.M011520200  0.656
2000 Salehi AH, Roux PP, Kubu CJ, Zeindler C, Bhakar A, Tannis LL, Verdi JM, Barker PA. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. Neuron. 27: 279-88. PMID 10985348 DOI: 10.1016/S0896-6273(00)00036-2  0.565
1999 Roux PP, Colicos MA, Barker PA, Kennedy TE. p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6887-96. PMID 10436046 DOI: 10.1523/Jneurosci.19-16-06887.1999  0.674
1999 Bhakar AL, Roux PP, Lachance C, Kryl D, Zeindler C, Barker PA. The p75 neurotrophin receptor (p75NTR) alters tumor necrosis factor-mediated NF-kappaB activity under physiological conditions, but direct p75NTR-mediated NF-kappaB activation requires cell stress. The Journal of Biological Chemistry. 274: 21443-9. PMID 10409708 DOI: 10.1074/Jbc.274.30.21443  0.496
1999 Kryl D, Yacoubian T, Haapasalo A, Castren E, Lo D, Barker PA. Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5823-33. PMID 10407023 DOI: 10.1523/Jneurosci.19-14-05823.1999  0.361
1997 MacPhee IJ, Barker PA. Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain Journal of Biological Chemistry. 272: 23547-23551. PMID 9295291 DOI: 10.1074/Jbc.272.38.23547  0.714
1997 Majdan M, Lachance C, Gloster A, Aloyz R, Zeindler C, Bamji S, Bhakar A, Belliveau D, Fawcett J, Miller FD, Barker PA. Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6988-98. PMID 9278534 DOI: 10.1523/Jneurosci.17-18-06988.1997  0.348
1994 Barker PA, Barbee G, Misko TP, Shooter EM. The low affinity neurotrophin receptor, p75LNTR, is palmitoylated by thioester formation through cysteine 279. The Journal of Biological Chemistry. 269: 30645-50. PMID 7982984  0.519
1994 Kahle P, Barker PA, Shooter EM, Hertel C. p75 nerve growth factor receptor modulates p140trkA kinase activity, but not ligand internalization, in PC12 cells. Journal of Neuroscience Research. 38: 599-606. PMID 7815475 DOI: 10.1002/Jnr.490380512  0.502
1994 Barker PA, Shooter EM. Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron. 13: 203-15. PMID 7519025 DOI: 10.1016/0896-6273(94)90470-7  0.483
1993 Barker PA, Lomen-Hoerth C, Gensch EM, Meakin SO, Glass DJ, Shooter EM. Tissue-specific alternative splicing generates two isoforms of the trkA receptor. The Journal of Biological Chemistry. 268: 15150-7. PMID 8325889  0.529
1993 Drinkwater CC, Barker PA, Suter U, Shooter EM. The carboxyl terminus of nerve growth factor is required for biological activity. The Journal of Biological Chemistry. 268: 23202-7. PMID 8226840  0.618
1992 Ramsden CA, Markiewicz M, Walters DV, Gabella G, Parker KA, Barker PM, Neil HL. Liquid flow across the epithelium of the artificially perfused lung of fetal and postnatal sheep. The Journal of Physiology. 448: 579-97. PMID 1593479 DOI: 10.1113/jphysiol.1992.sp019059  0.335
1990 Barker PM, Markiewicz M, Parker KA, Walters DV, Strang LB. Synergistic action of triiodothyronine and hydrocortisone on epinephrine-induced reabsorption of fetal lung liquid. Pediatric Research. 27: 588-91. PMID 2356103 DOI: 10.1203/00006450-199006000-00010  0.331
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