Dane M. Chetkovich, MD, PhD - Publications

Affiliations: 
Neurology and Physiology Northwestern University, Evanston, IL 
Area:
Ion Channel Trafficking
Website:
http://www.neurology.northwestern.edu/faculty/chetkovich.html

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Foote KM, Lyman KA, Han Y, Michailidis IE, Heuermann RJ, Mandikian D, Trimmer JS, Swanson GT, Chetkovich DM. Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function. The Journal of Biological Chemistry. PMID 31492750 DOI: 10.1074/jbc.RA119.010027  0.44
2018 Fisher DW, Han Y, Lyman KA, Heuermann RJ, Bean LA, Ybarra N, Foote KM, Dong H, Nicholson DA, Chetkovich DM. HCN channels in the hippocampus regulate active coping behavior. Journal of Neurochemistry. PMID 29953635 DOI: 10.1111/jnc.14539  0.44
2018 Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, ... ... Chetkovich DM, et al. Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiology of Learning and Memory. PMID 29906573 DOI: 10.1016/j.nlm.2018.06.004  0.44
2017 Lyman KA, Han Y, Heuermann RJ, Cheng X, Kurz JE, Lyman RE, Van Veldhoven PP, Chetkovich DM. Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels. The Journal of Biological Chemistry. PMID 28887304 DOI: 10.1074/jbc.M117.802256  0.44
2017 Chen H, Judkins J, Thomas C, Wu M, Khoury L, Benjamin CG, Pacione D, Golfinos JG, Kumthekar P, Ghamsari F, Chen L, Lein P, Chetkovich DM, Snuderl M, Horbinski C. Mutant IDH1 and seizures in patients with glioma. Neurology. PMID 28404805 DOI: 10.1212/WNL.0000000000003911  0.88
2017 Lyman KA, Han Y, Chetkovich DM. Animal models suggest the TRIP8b-HCN interaction is a therapeutic target for Major Depressive Disorder. Expert Opinion On Therapeutic Targets. PMID 28127990 DOI: 10.1080/14728222.2017.1287899  0.44
2016 Han Y, Lyman KA, Clutter M, Schiltz GE, Ismail QA, Cheng X, Luan CH, Chetkovich DM. Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b. Journal of Visualized Experiments : Jove. PMID 27911380 DOI: 10.3791/54540  0.44
2016 Han Y, Heuermann RJ, Lyman KA, Fisher D, Ismail QA, Chetkovich DM. HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Molecular Psychiatry. PMID 27400855 DOI: 10.1038/mp.2016.99  1
2016 Kurz JE, Chetkovich DM. A Time and Place for Everything: Early-Life Seizures at Different Developmental Epochs Have Distinct Effects on Adult Hippocampal Structure and Function. Epilepsy Currents / American Epilepsy Society. 16: 106-7. PMID 27073344 DOI: 10.5698/1535-7511-16.2.106  1
2015 Heuermann RJ, Jaramillo TC, Ying SW, Suter BA, Lyman KA, Han Y, Lewis AS, Hampton TG, Shepherd GM, Goldstein PA, Chetkovich DM. Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy. Neurobiology of Disease. 85: 81-92. PMID 26459112 DOI: 10.1016/j.nbd.2015.10.005  1
2015 Han Y, Lyman K, Clutter M, Schiltz GE, Ismail QA, Prados DB, Luan CH, Chetkovich DM. Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels. Journal of Biomolecular Screening. 20: 1124-31. PMID 26045196 DOI: 10.1177/1087057115589590  1
2015 Lyman KA, Chetkovich DM. Cortical Compass: EML1 Helps Point the Way in Neuronal Migration. Epilepsy Currents / American Epilepsy Society. 15: 43-4. PMID 25678890 DOI: 10.5698/1535-7597-15.1.43  1
2014 Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich DM, Bähring R, Bender RA. Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2177-90. PMID 24451387 DOI: 10.1096/fj.13-242032  1
2014 Pan Y, Bhattarai S, Modestou M, Drack AV, Chetkovich DM, Baker SA. TRIP8b is required for maximal expression of HCN1 in the mouse retina. Plos One. 9: e85850. PMID 24409334 DOI: 10.1371/journal.pone.0085850  1
2013 Brager DH, Lewis AS, Chetkovich DM, Johnston D. Short- and long-term plasticity in CA1 neurons from mice lacking h-channel auxiliary subunit TRIP8b. Journal of Neurophysiology. 110: 2350-7. PMID 23966674 DOI: 10.1152/jn.00218.2013  1
2013 Dougherty KA, Nicholson DA, Diaz L, Buss EW, Neuman KM, Chetkovich DM, Johnston D. Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus. Journal of Neurophysiology. 109: 1940-53. PMID 23324324 DOI: 10.1152/jn.00010.2013  1
2012 Huang Z, Lujan R, Martinez-Hernandez J, Lewis AS, Chetkovich DM, Shah MM. TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14835-48. PMID 23077068 DOI: 10.1523/JNEUROSCI.1544-12.2012  1
2012 Bankston JR, Camp SS, DiMaio F, Lewis AS, Chetkovich DM, Zagotta WN. Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 7899-904. PMID 22550182 DOI: 10.1073/pnas.1201997109  1
2012 Marcelin B, Lugo JN, Brewster AL, Liu Z, Lewis AS, McClelland S, Chetkovich DM, Baram TZ, Anderson AE, Becker A, Esclapez M, Bernard C. Differential dorso-ventral distributions of Kv4.2 and HCN proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites. The Journal of Biological Chemistry. 287: 17656-61. PMID 22511771 DOI: 10.1074/jbc.C112.367110  1
2012 Marcelin B, Liu Z, Chen Y, Lewis AS, Becker A, McClelland S, Chetkovich DM, Migliore M, Baram TZ, Esclapez M, Bernard C. Dorsoventral differences in intrinsic properties in developing CA1 pyramidal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3736-47. PMID 22423094 DOI: 10.1523/JNEUROSCI.5870-11.2012  1
2012 Wilkars W, Liu Z, Lewis AS, Stoub TR, Ramos EM, Brandt N, Nicholson DA, Chetkovich DM, Bender RA. Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms. Plos One. 7: e32181. PMID 22363812 DOI: 10.1371/journal.pone.0032181  1
2012 Khurana S, Liu Z, Lewis AS, Rosa K, Chetkovich D, Golding NL. An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2814-23. PMID 22357864 DOI: 10.1523/JNEUROSCI.3882-11.2012  1
2012 Kanyshkova T, Meuth P, Bista P, Liu Z, Ehling P, Caputi L, Doengi M, Chetkovich DM, Pape HC, Budde T. Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains. Neurobiology of Disease. 45: 450-61. PMID 21945537 DOI: 10.1016/j.nbd.2011.08.032  1
2012 Chetkovich DM, Nicoll RA. Organization and regulation of the postsynaptic density Dendrites. DOI: 10.1093/acprof:oso/9780198566564.003.0006  1
2011 Lewis AS, Vaidya SP, Blaiss CA, Liu Z, Stoub TR, Brager DH, Chen X, Bender RA, Estep CM, Popov AB, Kang CE, Van Veldhoven PP, Bayliss DA, Nicholson DA, Powell CM, ... ... Chetkovich DM, et al. Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7424-40. PMID 21593326 DOI: 10.1523/JNEUROSCI.0936-11.2011  1
2011 Han Y, Noam Y, Lewis AS, Gallagher JJ, Wadman WJ, Baram TZ, Chetkovich DM. Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites. The Journal of Biological Chemistry. 286: 20823-34. PMID 21504900 DOI: 10.1074/jbc.M111.236125  1
2011 Lewis AS, Chetkovich DM. HCN channels in behavior and neurological disease: too hyper or not active enough? Molecular and Cellular Neurosciences. 46: 357-67. PMID 21130878 DOI: 10.1016/j.mcn.2010.11.007  1
2011 Chan CS, Glajch KE, Gertler TS, Guzman JN, Mercer JN, Lewis AS, Goldberg AB, Tkatch T, Shigemoto R, Fleming SM, Chetkovich DM, Osten P, Kita H, Surmeier DJ. HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease. Nature Neuroscience. 14: 85-92. PMID 21076425 DOI: 10.1038/nn.2692  1
2010 Hitt BD, Jaramillo TC, Chetkovich DM, Vassar R. BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization. Molecular Neurodegeneration. 5: 31. PMID 20731874 DOI: 10.1186/1750-1326-5-31  1
2010 Lewis AS, Estep CM, Chetkovich DM. The fast and slow ups and downs of HCN channel regulation. Channels (Austin, Tex.). 4: 215-31. PMID 20305382  1
2010 Noam Y, Zha Q, Phan L, Wu RL, Chetkovich DM, Wadman WJ, Baram TZ. Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons. The Journal of Biological Chemistry. 285: 14724-36. PMID 20215108 DOI: 10.1074/jbc.M109.070391  1
2010 Stein EL, Chetkovich DM. Regulation of stargazin synaptic trafficking by C-terminal PDZ ligand phosphorylation in bidirectional synaptic plasticity. Journal of Neurochemistry. 113: 42-53. PMID 19968761 DOI: 10.1111/j.1471-4159.2009.06529.x  1
2009 Lewis AS, Schwartz E, Chan CS, Noam Y, Shin M, Wadman WJ, Surmeier DJ, Baram TZ, Macdonald RL, Chetkovich DM. Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6250-65. PMID 19439603 DOI: 10.1523/JNEUROSCI.0856-09.2009  1
2009 Chung WK, Shin M, Jaramillo TC, Leibel RL, LeDuc CA, Fischer SG, Tzilianos E, Gheith AA, Lewis AS, Chetkovich DM. Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2. Neurobiology of Disease. 33: 499-508. PMID 19150498 DOI: 10.1016/j.nbd.2008.12.004  1
2008 Shin M, Brager D, Jaramillo TC, Johnston D, Chetkovich DM. Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy. Neurobiology of Disease. 32: 26-36. PMID 18657617 DOI: 10.1016/j.nbd.2008.06.013  1
2007 Shin M, Chetkovich DM. Activity-dependent regulation of h channel distribution in hippocampal CA1 pyramidal neurons. The Journal of Biological Chemistry. 282: 33168-80. PMID 17848552 DOI: 10.1074/jbc.M703736200  1
2006 Shin M, Simkin D, Suyeoka GM, Chetkovich DM. Evaluation of HCN2 abnormalities as a cause of juvenile audiogenic seizures in Black Swiss mice. Brain Research. 1083: 14-20. PMID 16542642 DOI: 10.1016/j.brainres.2006.01.102  1
2005 Chen JY, Chetkovich DM. Identification of PIST PDZ domain interactors Ethnicity and Disease. 15: S4-43-S4-44.  1
2004 Cuadra AE, Kuo SH, Kawasaki Y, Bredt DS, Chetkovich DM. AMPA receptor synaptic targeting regulated by stargazin interactions with the Golgi-resident PDZ protein nPIST. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7491-502. PMID 15329396 DOI: 10.1523/JNEUROSCI.1255-04.2004  1
2002 Misawa H, Sherr EH, Lee DJ, Chetkovich DM, Tan A, Schreiner CE, Bredt DS. Identification of a monogenic locus (jams1) causing juvenile audiogenic seizures in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10088-93. PMID 12451109  1
2002 Chetkovich DM, Bunn RC, Kuo SH, Kawasaki Y, Kohwi M, Bredt DS. Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6415-25. PMID 12151521  1
2002 Chetkovich DM, Chen L, Stocker TJ, Nicoll RA, Bredt DS. Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5791-6. PMID 12122038  1
2002 Fullerton HJ, Chetkovich DM, Wu YW, Smith WS, Johnston SC. Deaths from stroke in US children, 1979 to 1998. Neurology. 59: 34-9. PMID 12105304  1
2000 Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature. 408: 936-43. PMID 11140673 DOI: 10.1038/35050030  1
2000 El-Husseini AE, Schnell E, Chetkovich DM, Nicoll RA, Bredt DS. PSD-95 involvement in maturation of excitatory synapses. Science (New York, N.Y.). 290: 1364-8. PMID 11082065  1
2000 El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS. Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. The Journal of Cell Biology. 148: 159-72. PMID 10629226 DOI: 10.1083/jcb.148.1.159  1
1993 Chetkovich DM, Sweatt JD. nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase. Journal of Neurochemistry. 61: 1933-42. PMID 7901336  1
1993 Chetkovich DM, Klann E, Sweatt JD. Nitric oxide synthase-independent long-term potentiation in area CA1 of hippocampus. Neuroreport. 4: 919-22. PMID 7690266  1
1992 Sessoms JS, Chen SJ, Chetkovich DM, Powell CM, Roberson ED, Sweatt JD, Klann E. Ca(2+)-induced persistent protein kinase C activation in rat hippocampal homogenates. Second Messengers and Phosphoproteins. 14: 109-26. PMID 1345337  1
1991 Chetkovich DM, Gray R, Johnston D, Sweatt JD. N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 88: 6467-71. PMID 1677768  1
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