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Qinxi Guo - Publications

Affiliations: 
Baylor College of Medicine, Houston, TX 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Li H, Guo Q, Inoue T, Polito VA, Tabuchi K, Hammer RE, Pautler RG, Taffet GE, Zheng H. Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Molecular Neurodegeneration. 9: 28. PMID 25108425 DOI: 10.1186/1750-1326-9-28  0.695
2014 Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3826-40. PMID 24623762 DOI: 10.1523/Jneurosci.5171-13.2014  0.654
2013 Guo Q, Li H, Cole AL, Hur JY, Li Y, Zheng H. Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau. Plos One. 8: e80706. PMID 24278307 DOI: 10.1371/Journal.Pone.0080706  0.724
2013 Li H, Guo Q, Inoue T, Pautler R, Taffet G, Zheng H. P4-326: Abnormal cerebral blood flow exacerbates amyloid pathology in an Alzheimer's disease knock-in mice model Alzheimer's & Dementia. 9: P852-P852. DOI: 10.1016/J.Jalz.2013.08.160  0.609
2012 Guo Q, Zheng H, Justice NJ. Central CRF system perturbation in an Alzheimer's disease knockin mouse model. Neurobiology of Aging. 33: 2678-91. PMID 22336193 DOI: 10.1016/J.Neurobiolaging.2012.01.002  0.616
2012 Guo Q, Li H, Gaddam SS, Justice NJ, Robertson CS, Zheng H. Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives. The Journal of Biological Chemistry. 287: 2437-45. PMID 22144675 DOI: 10.1074/Jbc.M111.315051  0.722
2012 Guo Q, Wang Z, Li H, Wiese M, Zheng H. APP physiological and pathophysiological functions: insights from animal models. Cell Research. 22: 78-89. PMID 21769132 DOI: 10.1038/Cr.2011.116  0.761
2010 Li H, Wang B, Wang Z, Guo Q, Tabuchi K, Hammer RE, Südhof TC, Zheng H. Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proceedings of the National Academy of Sciences of the United States of America. 107: 17362-7. PMID 20855613 DOI: 10.1073/Pnas.1012568107  0.709
2010 Li H, Wang Z, Wang B, Guo Q, Dolios G, Tabuchi K, Hammer RE, Südhof TC, Wang R, Zheng H. Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis. The Journal of Biological Chemistry. 285: 30598-605. PMID 20693289 DOI: 10.1074/Jbc.M110.137729  0.706
2009 Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H. Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10788-801. PMID 19726636 DOI: 10.1523/Jneurosci.2132-09.2009  0.693
1999 Guo Q, Fu W, Holtsberg FW, Steiner SM, Mattson MP. Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations. Journal of Neuroscience Research. 56: 457-70. PMID 10369213 DOI: 10.1002/(Sici)1097-4547(19990601)56:5<457::Aid-Jnr2>3.0.Co;2-P  0.333
1999 Guo Q, Sebastian L, Sopher BL, Miller MW, Glazner GW, Ware CB, Martin GM, Mattson MP. Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation. Proceedings of the National Academy of Sciences of the United States of America. 96: 4125-30. PMID 10097174 DOI: 10.1073/Pnas.96.7.4125  0.371
1999 Guo Q, Sebastian L, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. Journal of Neurochemistry. 72: 1019-29. PMID 10037473 DOI: 10.1046/J.1471-4159.1999.0721019.X  0.459
1998 Furukawa K, Guo Q, Schellenberg GD, Mattson MP. Presenilin-1 mutation alters NGF-induced neurite outgrowth, calcium homeostasis, and transcription factor (AP-1) activation in PC12 cells. Journal of Neuroscience Research. 52: 618-24. PMID 9632318 DOI: 10.1002/(Sici)1097-4547(19980601)52:5<618::Aid-Jnr14>3.0.Co;2-Y  0.339
1998 Guo Q, Christakos S, Robinson N, Mattson MP. Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 95: 3227-32. PMID 9501245 DOI: 10.1073/Pnas.95.6.3227  0.38
1998 Mattson MP, Robinson N, Guo Q. Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1. Neuroreport. 8: 3817-21. PMID 9427376 DOI: 10.1097/00001756-199712010-00031  0.418
1998 Mattson MP, Guo Q, Furukawa K, Pedersen WA. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. Journal of Neurochemistry. 70: 1-14. PMID 9422341 DOI: 10.1046/J.1471-4159.1998.70010001.X  0.472
1998 Mattson MP, Guo Q. Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease? Journal of Neuroscience Research. 50: 505-13. PMID 9404712 DOI: 10.1002/(Sici)1097-4547(19971115)50:4<505::Aid-Jnr1>3.0.Co;2-I  0.565
1997 Pedersen WA, Guo Q, Hartman BK, Mattson MP. Nerve growth factor-independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1. The Journal of Biological Chemistry. 272: 22397-400. PMID 9278388 DOI: 10.1074/Jbc.272.36.22397  0.37
1997 Guo Q, Furukawa K, Sopher BL, Pham DG, Xie J, Robinson N, Martin GM, Mattson MP. Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide Neuroreport. 8: 379-383. PMID 9051814 DOI: 10.1097/00001756-199612200-00074  0.352
1997 Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP. Alzheimer’s Presenilin Mutation Sensitizes Neural Cells to Apoptosis Induced by Trophic Factor Withdrawal and Amyloid β-Peptide: Involvement of Calcium and Oxyradicals The Journal of Neuroscience. 17: 4212-4222. DOI: 10.1523/Jneurosci.17-11-04212.1997  0.415
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