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Steven E. Hyman, M.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Website:
http://www.provost.harvard.edu/people/

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Hyman SE, Landis SC, Leshner AI. Research Into Brain Disorders as an Example of Targeted Science. Jama. PMID 27668392 DOI: 10.1001/jama.2016.12412  0.44
2015 Hyman SE. Enlisting hESCs to Interrogate Genetic Variants Associated with Neuropsychiatric Disorders. Cell Stem Cell. 17: 253-4. PMID 26340523 DOI: 10.1016/j.stem.2015.08.013  1
2015 First MB, Reed GM, Hyman SE, Saxena S. The development of the ICD-11 Clinical Descriptions and Diagnostic Guidelines for Mental and Behavioural Disorders. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 14: 82-90. PMID 25655162 DOI: 10.1002/wps.20189  1
2015 Hyman SE. Neurobiology collides with moral and criminal responsibility: The result is double vision Free Will and the Brain: Neuroscientific, Philosophical, and Legal Perspectives. 231-250. DOI: 10.1017/CBO9781139565820.013  1
2014 Choi DW, Armitage R, Brady LS, Coetzee T, Fisher W, Hyman S, Pande A, Paul S, Potter W, Roin B, Sherer T. Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs. Neuron. 84: 554-63. PMID 25442934 DOI: 10.1016/j.neuron.2014.10.027  1
2014 Pankevich DE, Altevogt BM, Dunlop J, Gage FH, Hyman SE. Improving and accelerating drug development for nervous system disorders. Neuron. 84: 546-53. PMID 25442933 DOI: 10.1016/j.neuron.2014.10.007  1
2014 Hyman S. Mental health: Depression needs large human-genetics studies Nature. 515: 189-191. PMID 25391945 DOI: 10.1038/515189a  1
2014 Hyman SE. The unconscionable gap between what we know and what we do. Science Translational Medicine. 6: 253cm9. PMID 25210058 DOI: 10.1126/scitranslmed.3010312  1
2014 Hyman SE. How far can mice carry autism research? Cell. 158: 13-4. PMID 24995974 DOI: 10.1016/j.cell.2014.06.032  1
2014 McCarroll SA, Feng G, Hyman SE. Genome-scale neurogenetics: methodology and meaning. Nature Neuroscience. 17: 756-63. PMID 24866041 DOI: 10.1038/nn.3716  1
2014 Hyman SE. Perspective: Revealing molecular secrets. Nature. 508: S20. PMID 24695333 DOI: 10.1038/508S20a  1
2014 Hyman SE. Time for new schizophrenia Rx. Science (New York, N.Y.). 343: 1177. PMID 24626901 DOI: 10.1126/science.1252603  1
2014 Hyman SE. Revitalizing psychiatric therapeutics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 220-9. PMID 24317307 DOI: 10.1038/npp.2013.181  1
2014 Hyman SE. I Hope That We Are Not Living in a Post-Fact World Ajob Neuroscience. 5: 1-2. DOI: 10.1080/21507740.2014.923668  1
2013 McCarroll SA, Hyman SE. Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology. Neuron. 80: 578-87. PMID 24183011 DOI: 10.1016/j.neuron.2013.10.046  1
2013 Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ. DSM-5 and RDoC: progress in psychiatry research? Nature Reviews. Neuroscience. 14: 810-4. PMID 24135697 DOI: 10.1038/nrn3621  1
2013 Hyman SE. Might stimulant drugs support moral agency in ADHD children? Journal of Medical Ethics. 39: 369-70; discussion 3. PMID 23001921 DOI: 10.1136/medethics-2012-100846  1
2012 Hyman SE. Revolution stalled. Science Translational Medicine. 4: 155cm11. PMID 23052291 DOI: 10.1126/scitranslmed.3003142  1
2012 Hyman SE. Target practice: HDAC inhibitors for schizophrenia. Nature Neuroscience. 15: 1180-1. PMID 22929911 DOI: 10.1038/nn.3200  1
2011 Hyman SE. Commentary: Repairing a plane while it is flying--reflections on Rutter (2011). Journal of Child Psychology and Psychiatry, and Allied Disciplines. 52: 661-2; discussion 67. PMID 21434920 DOI: 10.1111/j.1469-7610.2011.02386.x  1
2011 Hyman SE. Genome-sequencing anniversary. The meaning of the Human Genome Project for neuropsychiatric disorders. Science (New York, N.Y.). 331: 1026. PMID 21350167 DOI: 10.1126/science.1203544  1
2011 Hyman SE. Cognitive enhancement: promises and perils. Neuron. 69: 595-8. PMID 21338872 DOI: 10.1016/j.neuron.2011.02.012  1
2011 Hyman SE. Grouping diagnoses of mental disorders by their common risk factors. The American Journal of Psychiatry. 168: 1-3. PMID 21205810 DOI: 10.1176/appi.ajp.2010.10111655  1
2011 Hyman SE. Biology of Addiction Goldman's Cecil Medicine: Twenty Fourth Edition. 1: 140-142. DOI: 10.1016/B978-1-4377-1604-7.00030-0  1
2011 Hyman SE, Andrews G, Ayuso-Mateos JL, Gaebel W, Goldberg DP, Gureje O, Jablensky A, Khoury B, Lovell A, Medina Mora ME, Rahimi-Movaghar A, Ritchie K, Saeed K, Sartorius N, Sharan P, et al. A conceptual framework for the revision of the ICD-10 classification of mental and behavioural disorders World Psychiatry. 10: 86-92.  1
2010 Hyman SE. Emerging neurotechnologies for lie-detection: where are we now? An appraisal of Wolpe, Foster and Langleben's "Emerging neurotechnologies for lie-detection: promise and perils" five years later. The American Journal of Bioethics : Ajob. 10: 49-50. PMID 20945267 DOI: 10.1080/15265161.2010.527263  1
2010 Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nature Neuroscience. 13: 1161-9. PMID 20877280 DOI: 10.1038/nn.2647  1
2010 Hyman SE. A bone to pick with compulsive behavior. Cell. 141: 752-4. PMID 20510922 DOI: 10.1016/j.cell.2010.05.010  1
2010 Hyman SE. The diagnosis of mental disorders: the problem of reification. Annual Review of Clinical Psychology. 6: 155-79. PMID 17716032 DOI: 10.1146/annurev.clinpsy.3.022806.091532  1
2010 Hyman SE. There may be better ways to earn a living Ajob Neuroscience. 1: 9-10. DOI: 10.1080/21507740.2010.517089  1
2009 Andrews G, Goldberg DP, Krueger RF, Carpenter WT, Hyman SE, Sachdev P, Pine DS. Exploring the feasibility of a meta-structure for DSM-V and ICD-11: could it improve utility and validity? Psychological Medicine. 39: 1993-2000. PMID 19796425 DOI: 10.1017/S0033291709990250  1
2009 Hyman SE. How adversity gets under the skin. Nature Neuroscience. 12: 241-3. PMID 19238182 DOI: 10.1038/nn0309-241  1
2008 Hyman SE. A glimmer of light for neuropsychiatric disorders. Nature. 455: 890-3. PMID 18923510 DOI: 10.1038/nature07454  1
2008 Hyman SE. How might cocaine interfere with brain development? Plos Medicine. 5: e130. PMID 18547140 DOI: 10.1371/journal.pmed.0050130  1
2008 Paletzki RF, Myakishev MV, Polesskaya O, Orosz A, Hyman SE, Vinson C. Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. Neuroscience. 152: 1040-53. PMID 18355967 DOI: 10.1016/j.neuroscience.2008.01.045  1
2008 Hyman SE, Ivleva E. Cognition in schizophrenia. The American Journal of Psychiatry. 165: 312. PMID 18316429 DOI: 10.1176/appi.ajp.2008.08010114  1
2007 Hyman SE. How mice cope with stressful social situations. Cell. 131: 232-4. PMID 17956724 DOI: 10.1016/j.cell.2007.10.008  1
2007 Hyman SE. Neuroscience: obsessed with grooming. Nature. 448: 871-2. PMID 17713517 DOI: 10.1038/448871a  1
2007 Hyman SE. Can neuroscience be integrated into the DSM-V? Nature Reviews. Neuroscience. 8: 725-32. PMID 17704814 DOI: 10.1038/nrn2218  1
2007 Hyman SE, Insel TR. Public health contributions. Schizophrenia Bulletin. 33: 1151-2. PMID 17631617 DOI: 10.1093/schbul/sbm084  1
2007 Hyman SE. The neurobiology of addiction: implications for voluntary control of behavior. The American Journal of Bioethics : Ajob. 7: 8-11. PMID 17366151 DOI: 10.1080/15265160601063969  1
2006 Moldin SO, Rubenstein JL, Hyman SE. Can autism speak to neuroscience? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6893-6. PMID 16807319 DOI: 10.1523/JNEUROSCI.1944-06.2006  1
2006 Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annual Review of Neuroscience. 29: 565-98. PMID 16776597 DOI: 10.1146/annurev.neuro.29.051605.113009  1
2006 Hyman SE. Even chromatin gets the blues. Nature Neuroscience. 9: 465-6. PMID 16568101 DOI: 10.1038/nn0406-465  1
2006 Sgambato-Faure V, Xiong Y, Berke JD, Hyman SE, Strehler EE. The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump. Biochemical and Biophysical Research Communications. 343: 630-7. PMID 16554037 DOI: 10.1016/j.bbrc.2006.03.020  1
2005 Hyman SE. Addiction: a disease of learning and memory. The American Journal of Psychiatry. 162: 1414-22. PMID 16055762 DOI: 10.1176/appi.ajp.162.8.1414  1
2005 Yehuda R, Hyman SE. The impact of terrorism on brain, and behavior: what we know and what we need to know. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1773-80. PMID 16012534 DOI: 10.1038/sj.npp.1300817  1
2005 Voulalas PJ, Holtzclaw L, Wolstenholme J, Russell JT, Hyman SE. Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3763-73. PMID 15829628 DOI: 10.1523/JNEUROSCI.4574-04.2005  1
2005 Hyman SE. Neurotransmitters. Current Biology : Cb. 15: R154-8. PMID 15753022 DOI: 10.1016/j.cub.2005.02.037  1
2004 Makris N, Gasic GP, Seidman LJ, Goldstein JM, Gastfriend DR, Elman I, Albaugh MD, Hodge SM, Ziegler DA, Sheahan FS, Caviness VS, Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, et al. Decreased absolute amygdala volume in cocaine addicts. Neuron. 44: 729-40. PMID 15541319 DOI: 10.1016/j.neuron.2004.10.027  1
2004 Montague PR, Hyman SE, Cohen JD. Computational roles for dopamine in behavioural control. Nature. 431: 760-7. PMID 15483596 DOI: 10.1038/nature03015  1
2003 Hyman SE. Methylphenidate-induced plasticity: what should we be looking for? Biological Psychiatry. 54: 1310-1. PMID 14675793 DOI: 10.1016/j.biopsych.2003.10.003  1
2003 Hyman SE. Diagnosing disorders. Scientific American. 289: 96-103. PMID 12951833  1
2003 Sgambato V, Minassian R, Nairn AC, Hyman SE. Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons. Journal of Neurochemistry. 86: 153-64. PMID 12807435 DOI: 10.1046/j.1471-4159.2003.01816.x  1
2003 Hyman SE, Fenton WS. Medicine. What are the right targets for psychopharmacology? Science (New York, N.Y.). 299: 350-1. PMID 12532001 DOI: 10.1126/science.1077141  1
2002 Kopnisky KL, Cowan WM, Hyman SE. Levels of analysis in psychiatric research. Development and Psychopathology. 14: 437-61. PMID 12349868 DOI: 10.1017.S0954579402003033  1
2002 Hyman SE. Neuroscience, genetics, and the future of psychiatric diagnosis. Psychopathology. 35: 139-44. PMID 12145499 DOI: 10.1159/000065134  1
2002 Kupfer DJ, Hyman SE, Schatzberg AF, Pincus HA, Reynolds CF. Recruiting and retaining future generations of physician scientists in mental health. Archives of General Psychiatry. 59: 657-60. PMID 12090819  1
2002 Hyman SE. A new beginning for research on borderline personality disorder. Biological Psychiatry. 51: 933-5. PMID 12062876 DOI: 10.1016/S0006-3223(02)01408-7  1
2002 Cowan WM, Kopnisky KL, Hyman SE. The human genome project and its impact on psychiatry. Annual Review of Neuroscience. 25: 1-50. PMID 12052903 DOI: 10.1146/annurev.neuro.25.112701.142853  1
2002 Kopnisky KL, Hyman SE. Psychiatry in the postgenomic era Economics of Neuroscience. 4: 27-31.  1
2001 Hyman SE. Mental health in an aging population: the NIMH perspective. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 9: 330-9. PMID 11739060 DOI: 10.1097/00019442-200111000-00002  1
2001 Hyman SE. A 28-year-old man addicted to cocaine. Jama. 286: 2586-94. PMID 11722273  1
2001 Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE. Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Neuron. 32: 277-87. PMID 11683997 DOI: 10.1016/S0896-6273(01)00465-2  1
2001 Hyman SE, Malenka RC. Addiction and the brain: the neurobiology of compulsion and its persistence. Nature Reviews. Neuroscience. 2: 695-703. PMID 11584307 DOI: 10.1038/35094560  1
2001 Biederman J, Birmaher B, Carlson GA, Chang KD, Fenton WS, Geller B, Hoagwood KE, Hyman SE, Kendler KS, Koretz DS, Kowatch RA, Kupfer DJ, Leibenluft E, Nakamura RK, Nottelmann ED, et al. National Institute of Mental Health research roundtable on prepubertal bipolar disorder Journal of the American Academy of Child and Adolescent Psychiatry. 40: 871-878. PMID 11501685  1
2001 Hyman SE. Mood disorders in children and adolescents: An epidemiologic perspective Biological Psychiatry. 49: 1002-1014. PMID 11430842 DOI: 10.1016/S0006-3223(01)01129-5  1
2001 Kosofsky BE, Hyman SE. No time for complacency: the fetal brain on drugs. The Journal of Comparative Neurology. 435: 259-62. PMID 11406809 DOI: 10.1002/cne.1027  1
2001 Shore D, Goldschmidts W, Wynne D, Hyman SE. NIMH perspective: Meeting national needs for psychiatrist-researchers Academic Psychiatry. 25: 9-11. DOI: 10.1176/appi.ap.25.1.9  1
2000 Hyman SE. Mental illness: Genetically complex disorders of neural circuitry and neural communication Neuron. 28: 321-323. PMID 11144341  1
2000 Hyman SE. The needs for database research and for privacy collide. The American Journal of Psychiatry. 157: 1723-4. PMID 11058462 DOI: 10.1176/appi.ajp.157.11.1723  1
2000 Hyman SE. Genes, gene expression, and behavior. Neurobiology of Disease. 7: 528-32. PMID 11042069 DOI: 10.1006/nbdi.2000.0347  1
2000 Hyman SE. Goals for research on bipolar disorder: the view from NIMH. Biological Psychiatry. 48: 436-41. PMID 11018216 DOI: 10.1016/S0006-3223(00)00894-5  1
2000 Hyman SE. National Institute of Mental Health goals for behavioral science. Experimental and Clinical Psychopharmacology. 8: 271-2. PMID 10975615 DOI: 10.1037//1064-1297.8.3.271  1
2000 Hyman SE. The genetics of mental illness: implications for practice. Bulletin of the World Health Organization. 78: 455-63. PMID 10885164  1
2000 Berke JD, Hyman SE. Addiction, dopamine, and the molecular mechanisms of memory. Neuron. 25: 515-32. PMID 10774721  1
2000 Hyman SE, Shore D. An NIMH perspective on the use of placebos. National Institute of Mental Health. Biological Psychiatry. 47: 689-91. PMID 10773173 DOI: 10.1016/S0006-3223(99)00292-9  1
2000 Hyman SE. The NIMH perspective: next steps in schizophrenia research. Biological Psychiatry. 47: 1-7. PMID 10650443 DOI: 10.1016/S0006-3223(99)00077-3  1
2000 Hyman SE. The millennium of mind, brain, and behavior. Archives of General Psychiatry. 57: 88-9. PMID 10632239  1
1999 Shore D, Hyman SE. An NIMH commentary on the NBAC report. Biological Psychiatry. 46: 1013-6. PMID 10536736 DOI: 10.1016/S0006-3223(99)00228-0  1
1999 Shore D, Hyman SE. NIMH symptom challenge and medication discontinuation workshop. Biological Psychiatry. 46: 1009-10. PMID 10536734 DOI: 10.1016/S0006-3223(99)00191-2  1
1999 Norquist G, Hyman SE. Advances in understanding and treating mental illness: implications for policy. Health Affairs (Project Hope). 18: 32-47. PMID 10495590 DOI: 10.1377/hlthaff.18.5.32  1
1999 Hyman SE. Selective gene expression increases behavioral sensitivity to cocaine. Nature Neuroscience. 2: 855-6. PMID 10491599 DOI: 10.1038/13147  1
1999 Kobierski LA, Wong AE, Srivastava S, Borsook D, Hyman SE. Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase. Journal of Neurochemistry. 73: 129-38. PMID 10386963 DOI: 10.1046/j.1471-4159.1999.0730129.x  1
1999 Schwarzschild MA, Cole RL, Meyers MA, Hyman SE. Contrasting calcium dependencies of SAPK and ERK activations by glutamate in cultured striatal neurons. Journal of Neurochemistry. 72: 2248-55. PMID 10349832 DOI: 10.1046/j.1471-4159.1999.0722248.x  1
1999 Hyman SE. Protecting patients, preserving progress: ethics in mental health illness research. Academic Medicine : Journal of the Association of American Medical Colleges. 74: 258-9. PMID 10099647  1
1999 Hyman SE. Introduction to the complex genetics of mental disorders. Biological Psychiatry. 45: 518-21. PMID 10088041 DOI: 10.1016/S0006-3223(98)00332-1  1
1999 Van Koughnet K, Smirnova O, Hyman SE, Borsook D. Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin-1beta. The Journal of Comparative Neurology. 405: 199-215. PMID 10023810 DOI: 10.1002/(SICI)1096-9861(19990308)405:2<199::AID-CNE5>3.0.CO;2-W  1
1999 Hyman SE. Prevention of children's behavioral and mental health problems: New horizons for psychology. Foreword Clinical Psychology Review. 19: 387-390. DOI: 10.1016/S0272-7358(98)00101-9  1
1999 Ragnarsson KT, Clarke WR, Daling JR, Garber SL, Gustafson CF, Holland AL, Jordan BD, Parker JC, Riddle MA, Roth EJ, Seltzer MM, Simpson KN, Therrien B, Wexler BE, Yawn BP, ... ... Hyman SE, et al. Rehabilitation of persons with traumatic brain injury Journal of the American Medical Association. 282: 974-983. DOI: 10.1001/jama.282.10.974  1
1998 Hyman SE. Brain neurocircuitry of anxiety and fear: implications for clinical research and practice. Biological Psychiatry. 44: 1201-3. PMID 9861461 DOI: 10.1016/S0006-3223(98)00298-4  1
1998 Hyman SE. NIMH during the tenure of Director Steven E. Hyman, M.D. (1996-present): the now and future of NIMH. The American Journal of Psychiatry. 155: 36-40. PMID 9736863  1
1998 Genova LM, Hyman SE. 5-HT3 receptor activation is required for induction of striatal c-Fos and phosphorylation of ATF-1 by amphetamine. Synapse (New York, N.Y.). 30: 71-8. PMID 9704883 DOI: 10.1002/(SICI)1098-2396(199809)30:1<71::AID-SYN9>3.0.CO;2-H  1
1998 Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, ... ... Hyman SE, et al. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science (New York, N.Y.). 281: 838-42. PMID 9694658 DOI: 10.1126/science.281.5378.838  1
1998 Hyman SE, Zuckerman B. Drug interactions in cocaine abuse: methodologic concerns in human and animal studies. Annals of the New York Academy of Sciences. 846: 69-75. PMID 9668398 DOI: 10.1111/j.1749-6632.1998.tb09727.x  1
1998 Gollub RL, Breiter HC, Kantor H, Kennedy D, Gastfriend D, Mathew RT, Makris N, Guimaraes A, Riorden J, Campbell T, Foley M, Hyman SE, Rosen B, Weisskoff R. Cocaine decreases cortical cerebral blood flow but does not obscure regional activation in functional magnetic resonance imaging in human subjects. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 724-34. PMID 9663502 DOI: 10.1097/00004647-199807000-00003  1
1998 Berke JD, Paletzki RF, Aronson GJ, Hyman SE, Gerfen CR. A complex program of striatal gene expression induced by dopaminergic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5301-10. PMID 9651213  1
1998 Hyman SE. A new image for fear and emotion. Nature. 393: 417-8. PMID 9623995 DOI: 10.1038/30855  1
1998 Hyman SE. The K-05 award controversy. Archives of General Psychiatry. 55: 21-2. PMID 9435755  1
1997 Glick TH, Armstrong EG, Waterman MA, Hundert EM, Hyman SE. An integrated preclerkship curriculum in neuroscience, psychiatry, and neurology. Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry. 21: 212-8. PMID 24435648 DOI: 10.1007/BF03341434  1
1997 Glick TH, Armstrong EG, Hyman SE, Hundert EM, Furshpan EJ. Neurologic education for the future: a decade of curricular reform at Harvard Medical School. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 4: 102-6. PMID 24283899 DOI: 10.1111/j.1468-1331.1997.tb00312.x  1
1997 Genova L, Berke J, Hyman SE. Molecular adaptations to psychostimulants in striatal neurons: toward a pathophysiology of addiction. Neurobiology of Disease. 4: 239-46. PMID 9361300 DOI: 10.1006/nbdi.1997.0154  1
1997 Breiter HC, Gollub RL, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfriend DR, Riorden JP, Mathew RT, Rosen BR, Hyman SE. Acute effects of cocaine on human brain activity and emotion. Neuron. 19: 591-611. PMID 9331351 DOI: 10.1016/S0896-6273(00)80374-8  1
1997 Schwarzschild MA, Cole RL, Hyman SE. Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3455-66. PMID 9133371  1
1997 Klein DF, Hyman SE, Nestler EJ. Psychotropic drug action [12] (multiple letters) American Journal of Psychiatry. 154: 440-441. PMID 9072914  1
1996 Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 8019-26. PMID 8987828  1
1996 Breiter HC, Etcoff NL, Whalen PJ, Kennedy WA, Rauch SL, Buckner RL, Strauss MM, Hyman SE, Rosen BR. Response and habituation of the human amygdala during visual processing of facial expression. Neuron. 17: 875-87. PMID 8938120 DOI: 10.1016/S0896-6273(00)80219-6  1
1996 Hyman SE, Borsook D. Mechanisms regulating proenkephalin gene expression: contributions of transgenic models. Nida Research Monograph. 161: 59-71. PMID 8784844  1
1996 Konradi C, Leveque JC, Hyman SE. Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4231-9. PMID 8753884  1
1996 Hyman SE. Shaking out the cause of addiction. Science (New York, N.Y.). 273: 611-2. PMID 8701316  1
1996 Hyman SE. Addiction to cocaine and amphetamine. Neuron. 16: 901-4. PMID 8630246 DOI: 10.1016/S0896-6273(00)80111-7  1
1996 Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. The American Journal of Psychiatry. 153: 151-62. PMID 8561194  1
1996 Zenilman JM, Rompalo AM, Jadack R, Hyman SE. Clinical crossroads: Alcoholism and HIV infection [2] Journal of the American Medical Association. 275: 32-33. PMID 8531278 DOI: 10.1001/jama.275.1.32  1
1996 Hyman SE. Regulation of gene expression by neural signals Neuroscientist. 2: 217-224.  1
1995 Gollub RL, Hyman SE. G proteins and second messengers in psychiatry. Harvard Review of Psychiatry. 3: 41-4. PMID 9410573 DOI: 10.3109/10673229509017163  1
1995 Kosofsky BE, Genova LM, Hyman SE. Postnatal age defines specificity of immediate early gene induction by cocaine in developing rat brain. The Journal of Comparative Neurology. 351: 27-40. PMID 7896938 DOI: 10.1002/cne.903510104  1
1995 Cole RL, Konradi C, Douglass J, Hyman SE. Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron. 14: 813-23. PMID 7718243 DOI: 10.1016/0896-6273(95)90225-2  1
1995 Hyman SE. A man with alcoholism and HIV infection. Jama. 274: 837-43. PMID 7650809 DOI: 10.1001/jama.1995.03530100077038  1
1995 Konradi C, Cole RL, Green D, Senatus P, Leveque JC, Pollack AE, Grossbard SJ, Hyman SE. Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. Journal of Neurochemistry. 65: 1007-15. PMID 7643080  1
1995 Hyman SE, Cole RL, Konradi C, Kosofsky BE. Dopamine regulation of transcription factor-target interactions in rat striatum. Chemical Senses. 20: 257-60. PMID 7583020  1
1995 Borsook D, Hyman SE. Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS. The American Journal of Physiology. 269: E393-408. PMID 7573416  1
1995 Kosofsky BE, Genova LM, Hyman SE. Substance P phenotype defines specificity of c-fos induction by cocaine in developing rat striatum. The Journal of Comparative Neurology. 351: 41-50. PMID 7534774 DOI: 10.1002/cne.903510105  1
1994 Hyman SE, Gollub RL. More serotonin: not as simple as it seems. Harvard Review of Psychiatry. 2: 222-4. PMID 9384905 DOI: 10.3109/10673229409017140  1
1994 Hyman SE. Why does the brain prefer opium to broccoli? Harvard Review of Psychiatry. 2: 43-6. PMID 9384879 DOI: 10.3109/10673229409017114  1
1994 Hyman SE. Another one bites the dust: an infectious origin for peptic ulcers. Harvard Review of Psychiatry. 1: 294-5. PMID 9384861 DOI: 10.3109/10673229409017092  1
1994 Borsook D, Konradi C, Falkowski O, Comb M, Hyman SE. Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. Molecular Endocrinology (Baltimore, Md.). 8: 240-8. PMID 8170480 DOI: 10.1210/mend.8.2.8170480  1
1994 Borsook D, Falkowski O, Burstein R, Strassman A, Konradi C, Dauber A, Comb M, Hyman SE. Stress-induced regulation of a human proenkephalin-beta-galactosidase fusion gene in the hypothalamus of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 8: 116-25. PMID 8152426 DOI: 10.1210/mend.8.1.8152426  1
1994 Konradi C, Cole RL, Heckers S, Hyman SE. Amphetamine regulates gene expression in rat striatum via transcription factor CREB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5623-34. PMID 8083758  1
1994 Borsook D, Falkowski O, Rosen H, Comb M, Hyman SE. Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7261-71. PMID 7996174 DOI: 10.1016/0167-0115(94)90373-5  1
1994 Cole DG, Kobierski LA, Konradi C, Hyman SE. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 9631-5. PMID 7937819  1
1994 Hyman SE, Konradi C, Kobierski L, Cole R, Senatus P, Green D. Pharmacologic regulation of striatal proenkephalin gene expression via transcription factor CREB. Progress in Clinical and Biological Research. 390: 155-71. PMID 7724644  1
1994 Symes A, Lewis S, Corpus L, Rajan P, Hyman SE, Fink JS. STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines. Molecular Endocrinology (Baltimore, Md.). 8: 1750-63. PMID 7708062 DOI: 10.1210/mend.8.12.7708062  1
1994 Schwarzschild MA, Dauer WT, Lewis SE, Hamill LK, Fink JS, Hyman SE. Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. Journal of Neurochemistry. 63: 1246-54. PMID 7523587  1
1994 Lewis SE, Rao MS, Symes AJ, Dauer WT, Fink JS, Landis SC, Hyman SE. Coordinate regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. Journal of Neurochemistry. 63: 429-38. PMID 7518494  1
1994 Hyman SE, Konradi C, Cole RL. Regulation of striatal proenkephalin and prodynorphin gene expression by transcription factor CREB Regulatory Peptides. 54: 127-128. DOI: 10.1016/0167-0115(94)90422-7  1
1993 Hyman SE. New insights into how antipsychotic drugs might work. Harvard Review of Psychiatry. 1: 68-9. PMID 9384831 DOI: 10.3109/10673229309017060  1
1993 Hyman SE. Molecular and cell biology of addiction. Current Opinion in Neurology and Neurosurgery. 6: 609-13. PMID 8400475  1
1993 Konradi C, Kobierski LA, Nguyen TV, Heckers S, Hyman SE. The cAMP-response-element-binding protein interacts, but Fos protein does not interact, with the proenkephalin enhancer in rat striatum. Proceedings of the National Academy of Sciences of the United States of America. 90: 7005-9. PMID 8346209  1
1993 Hyman SE, Kosofsky BE, Nguyen TV, Cohen BM, Comb MJ. Everything activates c-fos--how can it matter? Nida Research Monograph. 125: 25-38. PMID 8341366  1
1993 Kosofsky BE, Hyman SE. The ontogeny of immediate early gene response to cocaine: a molecular analysis of the effects of cocaine on developing rat brain. Nida Research Monograph. 125: 161-71. PMID 8341363  1
1993 Symes AJ, Rao MS, Lewis SE, Landis SC, Hyman SE, Fink JS. Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line. Proceedings of the National Academy of Sciences of the United States of America. 90: 572-6. PMID 8093644  1
1992 Hope B, Kosofsky B, Hyman SE, Nestler EJ. Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proceedings of the National Academy of Sciences of the United States of America. 89: 5764-8. PMID 1631058 DOI: 10.1073/pnas.89.13.5764  1
1992 Comb MJ, Kobierski L, Chu HM, Tan Y, Borsook D, Herrup K, Hyman SE. Regulation of opioid gene expression: a model to understand neural plasticity. Nida Research Monograph. 126: 98-112. PMID 1491720  1
1992 Borsook D, Rosen H, Collard M, Dressler H, Herrup K, Comb MJ, Hyman SE. Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 1502-12. PMID 1435791 DOI: 10.1210/mend.6.9.1435791  1
1992 Nguyen TV, Kosofsky BE, Birnbaum R, Cohen BM, Hyman SE. Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine. Proceedings of the National Academy of Sciences of the United States of America. 89: 4270-4. PMID 1374894  1
1991 Comb M, Hyman SE, Kobierski L, Chu HM, Van Nguyen T. Mechanisms underlying synaptic regulation of proenkephalin transcription. Nida Research Monograph. 111: 149-70. PMID 1663581  1
1990 Ross ME, Evinger MJ, Hyman SE, Carroll JM, Mucke L, Comb M, Reis DJ, Joh TH, Goodman HM. Identification of a functional glucocorticoid response element in the phenylethanolamine N-methyltransferase promoter using fusion genes introduced into chromaffin cells in primary culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 520-30. PMID 2303857  1
1990 Van Nguyen T, Kobierski L, Comb M, Hyman SE. The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2825-33. PMID 2167356  1
1990 Cohen BM, Nguyen TV, Hyman SE. Cocaine-induced changes in gene expression in rat brain. Nida Research Monograph. 105: 175-81. PMID 1831539  1
1989 Hyman SE, Comb M, Pearlberg J, Goodman HM. An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene. Molecular and Cellular Biology. 9: 321-4. PMID 2538722  1
1988 Hyman SE. Recent developments in neurobiology: Part III. Effectors of transmitter action. Psychosomatics. 29: 373-8. PMID 2906447 DOI: 10.1016/S0033-3182(88)72336-1  1
1988 Hyman SE, Comb M, Lin YS, Pearlberg J, Green MR, Goodman HM. A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP. Molecular and Cellular Biology. 8: 4225-33. PMID 2903436  1
1988 Hyman SE. The role of molecular biology in psychiatry. Psychosomatics. 29: 328-32. PMID 2900535 DOI: 10.1016/S0033-3182(88)72371-3  1
1988 Hyman SE. Recent developments in neurobiology: Part II. Neurotransmitter receptors and psychopharmacology. Psychosomatics. 29: 254-63. PMID 2900534 DOI: 10.1016/S0033-3182(88)72361-0  1
1988 Comb M, Mermod N, Hyman SE, Pearlberg J, Ross ME, Goodman HM. Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription. The Embo Journal. 7: 3793-805. PMID 2850173  1
1988 Hyman SE. Recent developments in neurobiology: Part I. Synaptic transmission. Psychosomatics. 29: 157-65. PMID 2453072 DOI: 10.1016/S0033-3182(88)72392-0  1
1987 Schalling M, Dagerlind A, Brene S, Petterson R, Kvist S, Brownstein M, Hyman SE, Mucke L, Goodman HM, Joh TH. Localization of mRNA for phenylethanolamine N-methyltransferase (PNMT) using in situ hybridization. Acta Physiologica Scandinavica. 131: 631-2. PMID 3442246 DOI: 10.1111/j.1748-1716.1987.tb08288.x  1
1987 Pollack MH, Rosenbaum JF, Hyman SE. Calcium channel blockers in psychiatry. Psychosomatics. 28: 356-60, 369. PMID 3326023  1
1987 Comb M, Hyman SE, Goodman HM. Mechanisms of trans-synaptic regulation of gene expression Trends in Neurosciences. 10: 473-478. DOI: 10.1016/0166-2236(87)90103-2  1
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