Rosalind A. Segal - Publications

Affiliations: 
Harvard Medical School/Dana-Farber Cancer Institute, Boston, MA, United States 
Area:
Retrograde signaling, cerebellar development, cancer biology

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li Y, Pazyra-Murphy MF, Avizonis D, de Sá Tavares Russo M, Tang S, Chen CY, Hsueh YP, Bergholz JS, Jiang T, Zhao JJ, Zhu J, Ko KW, Milbrandt J, DiAntonio A, Segal RA. Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN. The Journal of Cell Biology. 221. PMID 34935867 DOI: 10.1083/jcb.202106080  0.353
2021 Merk DJ, Zhou P, Cohen SM, Pazyra-Murphy MF, Hwang GH, Rehm KJ, Alfaro J, Reid CM, Zhao X, Park E, Xu PX, Chan JA, Eck MJ, Nazemi KJ, Harwell CC, ... Segal RA, et al. The Eya1 Phosphatase Mediates Shh-Driven Symmetric Cell Division of Cerebellar Granule Cell Precursors. Developmental Neuroscience. 1-17. PMID 33472197 DOI: 10.1159/000512976  0.676
2021 Fukuda Y, Pazyra-Murphy MF, Silagi ES, Tasdemir-Yilmaz OE, Li Y, Rose L, Yeoh ZC, Vangos NE, Geffken EA, Seo HS, Adelmant G, Bird GH, Walensky LD, Marto JA, Dhe-Paganon S, ... Segal RA, et al. Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival. The Journal of Cell Biology. 220. PMID 33284322 DOI: 10.1083/jcb.202005051  0.337
2019 Staff NP, Fehrenbacher JC, Caillaud M, Damaj MI, Segal RA, Rieger S. Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems. Experimental Neurology. 113121. PMID 31758983 DOI: 10.1016/J.Expneurol.2019.113121  0.402
2019 Reitman ZJ, Paolella BR, Bergthold G, Pelton K, Becker S, Jones R, Sinai CE, Malkin H, Huang Y, Grimmet L, Herbert ZT, Sun Y, Weatherbee JL, Alberta JA, Daley JF, ... ... Segal RA, et al. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells. Nature Communications. 10: 3731. PMID 31427603 DOI: 10.1038/S41467-019-11493-2  0.608
2019 Reitman ZJ, Paolella B, Bergthold G, Pelton K, Jones R, Becker S, Sinai CE, Malkin H, Huang Y, Grimmett L, Herbert ZT, Sun Y, Weatherbee J, Alberta J, Daley J, ... ... Segal R, et al. Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas Cancer Research. 79: 3647-3647. DOI: 10.1158/1538-7445.Am2019-3647  0.598
2019 Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Sinai C, Malkin H, Huang Y, Grimmet L, Herbert Z, Sun Y, Weatherbee J, Qian K, Condurat A, ... ... Segal R, et al. LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS Neuro-Oncology. 21: ii99-ii99. DOI: 10.1093/Neuonc/Noz036.148  0.567
2018 Merk DJ, Segal RA. Sonic Hedgehog Signaling is Blue: Insights from the Patched Mutant Mice. Trends in Neurosciences. 41: 870-872. PMID 30471664 DOI: 10.1016/J.Tins.2018.08.013  0.334
2017 Pease-Raissi SE, Pazyra-Murphy MF, Li Y, Wachter F, Fukuda Y, Fenstermacher SJ, Barclay LA, Bird GH, Walensky LD, Segal RA. Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Neuron. 96: 373-386.e6. PMID 29024661 DOI: 10.1016/J.Neuron.2017.09.034  0.796
2017 Fukuda Y, Li Y, Segal RA. A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy. Frontiers in Neuroscience. 11: 481. PMID 28912674 DOI: 10.3389/Fnins.2017.00481  0.429
2017 Sun Y, Alberta JA, Pilarz C, Calligaris D, Chadwick EJ, Ramkissoon SH, Ramkissoon LA, Garcia VM, Mazzola E, Goumnerova L, Kane M, Yao Z, Kieran MW, Ligon KL, Hahn WC, ... ... Segal RA, et al. A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas. Neuro-Oncology. PMID 28082416 DOI: 10.1093/Neuonc/Now261  0.587
2016 Pak E, Segal RA. Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy. Developmental Cell. 38: 333-44. PMID 27554855 DOI: 10.1016/J.Devcel.2016.07.026  0.361
2016 Ni J, Xie S, Ramkissoon SH, Luu V, Sun Y, Bandopadhayay P, Beroukhim R, Roberts TM, Stiles CD, Segal RA, Ligon KL, Hahn WC, Zhao JJ. Tyrosine receptor kinase B is a drug target in astrocytomas. Neuro-Oncology. PMID 27402815 DOI: 10.1093/Neuonc/Now139  0.593
2016 Tasdemir-Yilmaz OE, Segal RA. There and back again: coordinated transcription, translation and transport in axonal survival and regeneration. Current Opinion in Neurobiology. 39: 62-68. PMID 27131422 DOI: 10.1016/J.Conb.2016.04.006  0.513
2016 Cosker KE, Fenstermacher SJ, Pazyra-Murphy MF, Elliott HL, Segal RA. The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability. Nature Neuroscience. PMID 27019013 DOI: 10.1038/Nn.4280  0.778
2016 Kieran MW, Sun Y, Pilarz C, Calligaris D, Chadwick EJ, Alberta JA, Ramkissoon SH, Ramkissoon LA, Garcia VM, Wilkinson K, Kane M, Goumnerova L, Chi SN, Manley P, Wright KD, ... ... Segal RA, et al. LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS Neuro-Oncology. 18: iii89.2-iii89. DOI: 10.1093/Neuonc/Now075.47  0.59
2015 Chadwick EJ, Yang DP, Filbin MG, Mazzola E, Sun Y, Behar O, Pazyra-Murphy MF, Goumnerova L, Ligon KL, Stiles CD, Segal RA. A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies. Journal of Visualized Experiments : Jove. PMID 26575352 DOI: 10.3791/53304  0.56
2015 Balastik M, Zhou XZ, Alberich-Jorda M, Weissova R, Žiak J, Pazyra-Murphy MF, Cosker KE, Machonova O, Kozmikova I, Chen CH, Pastorino L, Asara JM, Cole A, Sutherland C, Segal RA, et al. Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons. Cell Reports. 13: 812-28. PMID 26489457 DOI: 10.1016/J.Celrep.2015.09.026  0.816
2015 Zhao X, Segal RA. A Polyamine Twist on Hedgehog Signaling. Developmental Cell. 35: 1-2. PMID 26460938 DOI: 10.1016/J.Devcel.2015.09.024  0.319
2015 Zhou P, Erfani S, Liu Z, Jia C, Chen Y, Xu B, Deng X, Alfaro JE, Chen L, Napier D, Lu M, Huang JA, Liu C, Thibault O, Segal R, et al. CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion. Oncotarget. PMID 26377974 DOI: 10.18632/Oncotarget.4896  0.304
2015 Filbin MG, Segal RA. How neuronal activity regulates glioma cell proliferation. Neuro-Oncology. 17: 1543-4. PMID 26359210 DOI: 10.1093/Neuonc/Nov188  0.319
2015 Zhao X, Ponomaryov T, Ornell KJ, Zhou P, Dabral SK, Pak E, Li W, Atwood SX, Whitson RJ, Chang AL, Li J, Oro AE, Chan JA, Kelleher JF, Segal RA. RAS/MAPK activation drives resistance to Smo inhibition, metastasis and tumor evolution in Shh pathway-dependent tumors. Cancer Research. PMID 26130651 DOI: 10.1158/0008-5472.Can-14-2999-T  0.31
2015 Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, ... ... Segal R, et al. Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. Neuro-Oncology. PMID 25825052 DOI: 10.1093/Neuonc/Nov045  0.543
2015 Eisner A, Pazyra-Murphy MF, Durresi E, Zhou P, Zhao X, Chadwick EC, Xu PX, Hillman RT, Scott MP, Greenberg ME, Segal RA. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Developmental Cell. 33: 22-35. PMID 25816987 DOI: 10.1016/J.Devcel.2015.01.033  0.372
2014 Pease SE, Segal RA. Preserve and protect: maintaining axons within functional circuits. Trends in Neurosciences. 37: 572-82. PMID 25167775 DOI: 10.1016/J.Tins.2014.07.007  0.435
2014 Persson L, Witt RM, Galligan M, Greer PL, Eisner A, Pazyra-Murphy MF, Datta SR, Segal RA. Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry. Developmental Neurobiology. 74: 1255-67. PMID 24913191 DOI: 10.1002/Dneu.22202  0.73
2014 Bergthold G, Bandopadhayay P, Bi WL, Ramkissoon L, Stiles C, Segal RA, Beroukhim R, Ligon KL, Grill J, Kieran MW. Pediatric low-grade gliomas: how modern biology reshapes the clinical field. Biochimica Et Biophysica Acta. 1845: 294-307. PMID 24589977 DOI: 10.1016/J.Bbcan.2014.02.004  0.507
2014 Cosker KE, Segal RA. Neuronal signaling through endocytosis. Cold Spring Harbor Perspectives in Biology. 6. PMID 24492712 DOI: 10.1101/Cshperspect.A020669  0.819
2013 Pak E, Segal RA, Stiles CD. New progenitors NESTIN(g) in the EGL. Nature Neuroscience. 16: 1710-2. PMID 24270268 DOI: 10.1038/Nn.3580  0.521
2013 Filbin MG, Dabral SK, Pazyra-Murphy MF, Ramkissoon S, Kung AL, Pak E, Chung J, Theisen MA, Sun Y, Franchetti Y, Sun Y, Shulman DS, Redjal N, Tabak B, Beroukhim R, ... ... Segal RA, et al. Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities. Nature Medicine. 19: 1518-23. PMID 24076665 DOI: 10.1038/Nm.3328  0.442
2013 Witt RM, Hecht ML, Pazyra-Murphy MF, Cohen SM, Noti C, van Kuppevelt TH, Fuller M, Chan JA, Hopwood JJ, Seeberger PH, Segal RA. Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. The Journal of Biological Chemistry. 288: 26275-88. PMID 23867465 DOI: 10.1074/Jbc.M112.438937  0.736
2013 Cosker KE, Pazyra-Murphy MF, Fenstermacher SJ, Segal RA. Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5195-207. PMID 23516285 DOI: 10.1523/Jneurosci.3862-12.2013  0.794
2013 Courchesne SL, Pazyra-Murphy MF, Lee DJ, Segal RA. Cra1/+ mice show no evidence of motor neuron loss at symptomatic ages. Plos One. DOI: 10.1371/Journal.Pone.0016753.G002  0.766
2013 Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Segal R, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174  0.411
2011 Fainzilber M, Budnik V, Segal RA, Kreutz MR. From synapse to nucleus and back again--communication over distance within neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16045-8. PMID 22072654 DOI: 10.1523/Jneurosci.4006-11.2011  0.458
2011 Zhou P, Alfaro J, Chang EH, Zhao X, Porcionatto M, Segal RA. Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. Developmental Cell. 20: 610-22. PMID 21571219 DOI: 10.1016/J.Devcel.2011.04.006  0.359
2011 Courchesne SL, Pazyra-Murphy MF, Lee DJ, Segal RA. Neuromuscular junction defects in mice with mutation of dynein heavy chain 1. Plos One. 6: e16753. PMID 21346813 DOI: 10.1371/Journal.Pone.0016753  0.783
2011 Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA. Sensory neuropathy attributable to loss of Bcl-w. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1624-34. PMID 21289171 DOI: 10.1523/Jneurosci.3347-10.2011  0.803
2010 Cosker KE, Segal RA. The longer U(T)R, the further you go. Nature Neuroscience. 13: 273-5. PMID 20177416 DOI: 10.1038/Nn0310-273  0.801
2009 Gruber-Olipitz M, Segal RA. Live or let die: CCM2 provides the link. Neuron. 63: 559-60. PMID 19755097 DOI: 10.1016/J.Neuron.2009.08.030  0.393
2009 Arimura N, Kimura T, Nakamuta S, Taya S, Funahashi Y, Hattori A, Shimada A, Ménager C, Kawabata S, Fujii K, Iwamatsu A, Segal RA, Fukuda M, Kaibuchi K. Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. Developmental Cell. 16: 675-86. PMID 19460344 DOI: 10.1016/J.Devcel.2009.03.005  0.489
2009 Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, Heerssen HM, Watson FL, Kim T, Greenberg ME, Segal RA. A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6700-9. PMID 19458239 DOI: 10.1523/Jneurosci.0233-09.2009  0.771
2009 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nature Neuroscience. 12: 409-17. PMID 19287388 DOI: 10.1038/Nn.2287  0.761
2009 Witt RM, Galligan MM, Despinoy JR, Segal R. Olfactory behavioral testing in the adult mouse. Journal of Visualized Experiments : Jove. PMID 19229182 DOI: 10.3791/949  0.694
2008 Pazyra-Murphy MF, Segal RA. Preparation and maintenance of dorsal root ganglia neurons in compartmented cultures. Journal of Visualized Experiments : Jove. PMID 19078939 DOI: 10.3791/951  0.514
2008 Cosker KE, Courchesne SL, Segal RA. Action in the axon: generation and transport of signaling endosomes. Current Opinion in Neurobiology. 18: 270-5. PMID 18778772 DOI: 10.1016/J.Conb.2008.08.005  0.801
2008 Ha J, Lo KW, Myers KR, Carr TM, Humsi MK, Rasoul BA, Segal RA, Pfister KK. A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes. The Journal of Cell Biology. 181: 1027-39. PMID 18559670 DOI: 10.1083/Jcb.200803150  0.348
2007 Zhou P, Porcionatto M, Pilapil M, Chen Y, Choi Y, Tolias KF, Bikoff JB, Hong EJ, Greenberg ME, Segal RA. Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron. 55: 53-68. PMID 17610817 DOI: 10.1016/J.Neuron.2007.05.030  0.558
2006 Redjal N, Chan JA, Segal RA, Kung AL. CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6765-71. PMID 17121897 DOI: 10.1158/1078-0432.Ccr-06-1372  0.313
2005 Choi Y, Borghesani PR, Chan JA, Segal RA. Migration from a mitogenic niche promotes cell-cycle exit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10437-45. PMID 16280582 DOI: 10.1523/Jneurosci.1559-05.2005  0.513
2004 Heerssen HM, Pazyra MF, Segal RA. Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nature Neuroscience. 7: 596-604. PMID 15122257 DOI: 10.1038/Nn1242  0.824
2003 Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, Kieran MW, Luster AD, Segal RA. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 100: 13513-8. PMID 14595012 DOI: 10.1073/Pnas.2235846100  0.344
2003 Kim JY, Nelson AL, Algon SA, Graves O, Sturla LM, Goumnerova LC, Rowitch DH, Segal RA, Pomeroy SL. Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Developmental Biology. 263: 50-66. PMID 14568546 DOI: 10.1016/S0012-1606(03)00434-2  0.351
2003 Rubin JB, Segal RA. Growth, survival and migration: the Trk to cancer. Cancer Treatment and Research. 115: 1-18. PMID 12613191 DOI: 10.1007/0-306-48158-8_1  0.324
2003 Segal RA. Selectivity in neurotrophin signaling: theme and variations. Annual Review of Neuroscience. 26: 299-330. PMID 12598680 DOI: 10.1146/Annurev.Neuro.26.041002.131421  0.452
2003 Carter AR, Berry EM, Segal RA. Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning. Molecular and Cellular Neurosciences. 22: 1-13. PMID 12595234 DOI: 10.1016/S1044-7431(02)00015-5  0.365
2002 Wang KC, Kim JA, Sivasankaran R, Segal R, He Z. P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. Nature. 420: 74-8. PMID 12422217 DOI: 10.1038/Nature01176  0.422
2002 Bhattacharyya A, Watson FL, Pomeroy SL, Zhang YZ, Stiles CD, Segal RA. High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. Journal of Neurobiology. 51: 302-12. PMID 12150505 DOI: 10.1002/Neu.10062  0.648
2002 Ginty DD, Segal RA. Retrograde neurotrophin signaling: Trk-ing along the axon. Current Opinion in Neurobiology. 12: 268-74. PMID 12049932 DOI: 10.1016/S0959-4388(02)00326-4  0.536
2002 Rubin JB, Choi Y, Segal RA. Cerebellar proteoglycans regulate sonic hedgehog responses during development. Development (Cambridge, England). 129: 2223-32. PMID 11959830  0.475
2002 Heerssen HM, Segal RA. Location, location, location: a spatial view of neurotrophin signal transduction. Trends in Neurosciences. 25: 160-5. PMID 11852149 DOI: 10.1016/S0166-2236(02)02144-6  0.805
2002 Carter AR, Chen C, Schwartz PM, Segal RA. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1316-27. PMID 11850459 DOI: 10.1523/Jneurosci.22-04-01316.2002  0.314
2001 Segal R. Neurotrophins: which way did they go? Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001: PE1. PMID 11752653 DOI: 10.1126/Stke.2001.84.Pe1  0.434
2001 Watson FL, Heerssen HM, Bhattacharyya A, Klesse L, Lin MZ, Segal RA. Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nature Neuroscience. 4: 981-8. PMID 11544482 DOI: 10.1038/Nn720  0.812
2001 Choi DY, Toledo-Aral JJ, Segal R, Halegoua S. Sustained signaling by phospholipase C-γ mediates nerve growth factor-triggered gene expression Molecular and Cellular Biology. 21: 2695-2705. PMID 11283249 DOI: 10.1128/Mcb.21.8.2695-2705.2001  0.38
2001 Carter AR, Segal RA. Rett syndrome model suggests MECP2 gives neurons the quiet they need to think. Nature Neuroscience. 4: 342-3. PMID 11276217 DOI: 10.1038/85970  0.308
2000 O'Brien SP, Seipel K, Medley QG, Bronson R, Segal R, Streuli M. Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. 97: 12074-8. PMID 11050238 DOI: 10.1073/Pnas.97.22.12074  0.357
2000 Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA. Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5671-8. PMID 10908605 DOI: 10.1523/Jneurosci.20-15-05671.2000  0.399
1999 Watson FL, Heerssen HM, Moheban DB, Lin MZ, Sauvageot CM, Bhattacharyya A, Pomeroy SL, Segal RA. Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7889-900. PMID 10479691 DOI: 10.1523/Jneurosci.19-18-07889.1999  0.803
1999 Watson FL, Porcionatto MA, Bhattacharyya A, Stiles CD, Segal RA. TrkA glycosylation regulates receptor localization and activity. Journal of Neurobiology. 39: 323-36. PMID 10235685 DOI: 10.1002/(Sici)1097-4695(199905)39:2<323::Aid-Neu15>3.0.Co;2-4  0.597
1999 Kim JY, Sutton ME, Lu DJ, Cho TA, Goumnerova LC, Goritchenko L, Kaufman JR, Lam KK, Billet AL, Tarbell NJ, Wu J, Allen JC, Stiles CD, Segal RA, Pomeroy SL. Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas. Cancer Research. 59: 711-9. PMID 9973222  0.538
1998 Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, Bronson RT, Springer TA. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 9448-53. PMID 9689100 DOI: 10.1073/Pnas.95.16.9448  0.317
1998 Schwartz PM, Levy RL, Borghesani PR, Segal RA. Cerebellar pathology in BDNF -/- mice: the classic view of neurotrophins is changing. Molecular Psychiatry. 3: 116-20. PMID 9577835 DOI: 10.1038/Sj.Mp.4000359  0.344
1997 Pomeroy SL, Sutton ME, Goumnerova LC, Segal RA. Neurotrophins in cerebellar granule cell development and medulloblastoma. Journal of Neuro-Oncology. 35: 347-52. PMID 9440031 DOI: 10.1023/A:1005841206252  0.314
1997 Schwartz PM, Borghesani PR, Levy RL, Pomeroy SL, Segal RA. Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning. Neuron. 19: 269-81. PMID 9292718 DOI: 10.1016/S0896-6273(00)80938-1  0.408
1997 Bhattacharyya A, Watson FL, Bradlee TA, Pomeroy SL, Stiles CD, Segal RA. Trk receptors function as rapid retrograde signal carriers in the adult nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7007-16. PMID 9278536 DOI: 10.1523/Jneurosci.17-18-07007.1997  0.679
1997 Cabelli RJ, Shelton DL, Segal RA, Shatz CJ. Blockade of endogenous ligands of trkB inhibits formation of ocular dominance columns. Neuron. 19: 63-76. PMID 9247264 DOI: 10.1016/S0896-6273(00)80348-7  0.368
1997 Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (New York, N.Y.). 275: 661-5. PMID 9005851 DOI: 10.1126/Science.275.5300.661  0.364
1996 Segal RA, Greenberg ME. Intracellular signaling pathways activated by neurotrophic factors. Annual Review of Neuroscience. 19: 463-89. PMID 8833451 DOI: 10.1146/Annurev.Ne.19.030196.002335  0.432
1996 Segal RA, Bhattacharyya A, Rua LA, Alberta JA, Stephens RM, Kaplan DR, Stiles CD. Differential utilization of Trk autophosphorylation sites. The Journal of Biological Chemistry. 271: 20175-81. PMID 8702742 DOI: 10.1074/Jbc.271.33.20175  0.613
1995 Segal RA, Pomeroy SL, Stiles CD. Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4970-81. PMID 7623126 DOI: 10.1523/Jneurosci.15-07-04970.1995  0.666
1994 Segal RA, Goumnerova LC, Kwon YK, Stiles CD, Pomeroy SL. Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proceedings of the National Academy of Sciences of the United States of America. 91: 12867-71. PMID 7809137 DOI: 10.1073/Pnas.91.26.12867  0.551
1992 Segal RA, Takahashi H, McKay RD. Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. Neuron. 9: 1041-52. PMID 1463606 DOI: 10.1016/0896-6273(92)90064-K  0.387
1985 Segal RA, Luck DJ. Phosphorylation in isolated Chlamydomonas axonemes: a phosphoprotein may mediate the Ca2+-dependent photophobic response. The Journal of Cell Biology. 101: 1702-12. PMID 4055893 DOI: 10.1083/Jcb.101.5.1702  0.607
1984 Segal RA, Huang B, Ramanis Z, Luck DJ. Mutant strains of Chlamydomonas reinhardtii that move backwards only. The Journal of Cell Biology. 98: 2026-34. PMID 6725408 DOI: 10.1083/Jcb.98.6.2026  0.6
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