Eckard Wimmer - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 

295 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Le Nouën C, Luongo CL, Yang L, Mueller S, Wimmer E, DiNapoli JM, Collins PL, Buchholz UJ. Optimization of the codon-pair usage of human respiratory syncytial virus paradoxically resulted in reduced viral replication and reduced immunogenicity. Journal of Virology. PMID 31666376 DOI: 10.1128/JVI.01296-19  1
2019 Stauft CB, Song Y, Gorbatsevych O, Pantoja P, Rodriguez IV, Futcher B, Sariol CA, Wimmer E. Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2. Virology. 537: 237-245. PMID 31539771 DOI: 10.1016/j.virol.2019.09.003  0.8
2019 Song Y, Mugavero J, Stauft CB, Wimmer E. Dengue and Zika Virus 5' Untranslated Regions Harbor Internal Ribosomal Entry Site Functions. Mbio. 10. PMID 30967466 DOI: 10.1128/mBio.00459-19  0.8
2018 Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E. Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes. Plos One. 13: e0198303. PMID 30192757 DOI: 10.1371/journal.pone.0198303  1
2017 Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E. Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973853 DOI: 10.1073/pnas.1714385114  1
2017 Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, et al. Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049853 DOI: 10.1073/pnas.1619242114  1
2016 Asare E, Mugavero J, Jiang P, Wimmer E, Paul AV. A single amino acid substitution in the nonstructural protein 2CATPase of poliovirus causes conditional defects in encapsidation and uncoating. Journal of Virology. PMID 27076638 DOI: 10.1128/JVI.02877-15  0.96
2016 Sanders BP, de Los Rios Oakes I, van Hoek V, Bockstal V, Kamphuis T, Uil TG, Song Y, Cooper G, Crawt LE, Martín J, Zahn R, Lewis J, Wimmer E, Custers JH, Schuitemaker H, et al. Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine. Plos Pathogens. 12: e1005483. PMID 27032093 DOI: 10.1371/journal.ppat.1005483  1
2016 Agol V, Cello J, Chumakov K, Ehrenfeld E, Wimmer E. Eradicating polio: A balancing act. Science (New York, N.Y.). 351: 348. PMID 26798005 DOI: 10.1126/science.351.6271.348-b  1
2015 Broadbent AJ, Santos CP, Anafu A, Wimmer E, Mueller S, Subbarao K. Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets. Vaccine. PMID 26655630 DOI: 10.1016/j.vaccine.2015.11.054  1
2015 Sanders BP, Oakes IL, van Hoek V, Liu Y, Marissen W, Minor PD, Wimmer E, Schuitemaker H, Custers JH, Macadam A, Cello J, Edo-Matas D. Production of high titer attenuated poliovirus strains on the serum-free PER.C6(®) cell culture platform for the generation of safe and affordable next generation IPV. Vaccine. PMID 26529068 DOI: 10.1016/j.vaccine.2015.10.091  1
2015 Schmitt-Engel C, Schultheis D, Schwirz J, Ströhlein N, Troelenberg N, Majumdar U, Dao VA, Grossmann D, Richter T, Tech M, Dönitz J, Gerischer L, Theis M, Schild I, Trauner J, ... ... Wimmer EA, et al. The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology. Nature Communications. 6: 7822. PMID 26215380 DOI: 10.1038/ncomms8822  0.4
2015 Futcher B, Gorbatsevych O, Shen SH, Stauft CB, Song Y, Wang B, Leatherwood J, Gardin J, Yurovsky A, Mueller S, Wimmer E. Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished. Proceedings of the National Academy of Sciences of the United States of America. 112: E3635-6. PMID 26071446 DOI: 10.1073/pnas.1507710112  1
2015 Sanders BP, Liu Y, Brandjes A, van Hoek V, de Los Rios Oakes I, Lewis J, Wimmer E, Custers JH, Schuitemaker H, Cello J, Edo-Matas D. Brunenders: A partially attenuated historic poliovirus Type I vaccine strain. The Journal of General Virology. PMID 26018960 DOI: 10.1099/vir.0.000197  1
2015 Wang B, Yang C, Tekes G, Mueller S, Paul A, Whelan SP, Wimmer E. Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate. Mbio. 6. PMID 25827413 DOI: 10.1128/mBio.00237-15  1
2015 Shen SH, Stauft CB, Gorbatsevych O, Song Y, Ward CB, Yurovsky A, Mueller S, Futcher B, Wimmer E. Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference. Proceedings of the National Academy of Sciences of the United States of America. 112: 4749-54. PMID 25825721 DOI: 10.1073/pnas.1502864112  1
2015 Chen YH, Du W, Hagemeijer MC, Takvorian PM, Pau C, Cali A, Brantner CA, Stempinski ES, Connelly PS, Ma HC, Jiang P, Wimmer E, Altan-Bonnet G, Altan-Bonnet N. Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses. Cell. 160: 619-30. PMID 25679758 DOI: 10.1016/j.cell.2015.01.032  1
2015 Paul AV, Wimmer E. Initiation of protein-primed picornavirus RNA synthesis. Virus Research. 206: 12-26. PMID 25592245 DOI: 10.1016/j.virusres.2014.12.028  1
2015 Rozanska X, Ungerer P, Leblanc B, Saxe P, Wimmer E. Automatic and systematic atomistic simulations in the medeaβ software environment: Application to EU-REACH | Simulations atomistiques automatiques et systématiques dans l’environnement logiciel de MedeA® : Application à EU-REACH Oil and Gas Science and Technology. 70: 405-417. DOI: 10.2516/ogst/2014041  0.32
2014 Dippel S, Oberhofer G, Kahnt J, Gerischer L, Opitz L, Schachtner J, Stanke M, Schütz S, Wimmer EA, Angeli S. Tissue-specific transcriptomics, chromosomal localization, and phylogeny of chemosensory and odorant binding proteins from the red flour beetle Tribolium castaneum reveal subgroup specificities for olfaction or more general functions. Bmc Genomics. 15: 1141. PMID 25523483 DOI: 10.1186/1471-2164-15-1141  0.4
2014 Eckermann KN, Dippel S, KaramiNejadRanjbar M, Ahmed HM, Curril IM, Wimmer EA. Perspective on the combined use of an independent transgenic sexing and a multifactorial reproductive sterility system to avoid resistance development against transgenic Sterile Insect Technique approaches. Bmc Genetics. 15: S17. PMID 25471733 DOI: 10.1186/1471-2156-15-S2-S17  0.4
2014 Scolari F, Yuval B, Gomulski LM, Schetelig MF, Gabrieli P, Bassetti F, Wimmer EA, Malacrida AR, Gasperi G. Polyandry in the medfly - shifts in paternity mediated by sperm stratification and mixing. Bmc Genetics. 15: S10. PMID 25470981 DOI: 10.1186/1471-2156-15-S2-S10  0.4
2014 Jiang P, Liu Y, Ma HC, Paul AV, Wimmer E. Picornavirus morphogenesis. Microbiology and Molecular Biology Reviews : Mmbr. 78: 418-37. PMID 25184560 DOI: 10.1128/MMBR.00012-14  1
2014 Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proceedings of the National Academy of Sciences of the United States of America. 111: 13169-74. PMID 25157129 DOI: 10.1073/pnas.1411290111  1
2014 Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E. Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation. The Journal of General Virology. 95: 1668-76. PMID 24784416 DOI: 10.1099/vir.0.064535-0  1
2014 Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Binding of glutathione to enterovirus capsids is essential for virion morphogenesis. Plos Pathogens. 10: e1004039. PMID 24722756 DOI: 10.1371/journal.ppat.1004039  1
2014 Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P. An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. Plos Pathogens. 10: e1004052. PMID 24722315 DOI: 10.1371/journal.ppat.1004052  1
2014 Wang C, Ma HC, Wimmer E, Jiang P, Paul AV. A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis. The Journal of General Virology. 95: 1255-65. PMID 24558221 DOI: 10.1099/vir.0.062497-0  1
2014 Wimmer E, Freeman C, Christensen M, Wolf W, Rigby D, Hamm WL, Saxe P. Atomistic simulations as part of an integrated computational environment for structural design 55th Aiaa/Asme/Asce/Ahs/Sc Structures, Structural Dynamics, and Materials Conference. DOI: 10.2514/6.2014-0996  0.32
2014 Ogaugwu CE, Curril IM, Wimmer EA. Generation time extension for cost-effective strain maintenance of transgenic Mediterranean fruit fly, Ceratitis capitata [Diptera: Tephritidae] Journal of Applied Entomology. 138: 468-473. DOI: 10.1111/jen.12040  0.4
2014 Asahi R, Freeman CM, Saxe P, Wimmer E. Thermal expansion, diffusion and melting of Li2O using a compact forcefield derived from ab initio molecular dynamics Modelling and Simulation in Materials Science and Engineering. 22. DOI: 10.1088/0965-0393/22/7/075009  0.32
2014 Rozanska X, Stewart JJP, Ungerer P, Leblanc B, Freeman C, Saxe P, Wimmer E. High-throughput calculations of molecular properties in the MedeA environment: Accuracy of PM7 in predicting vibrational frequencies, ideal gas entropies, heat capacities, and gibbs free energies of organic molecules Journal of Chemical and Engineering Data. 59: 3136-3143. DOI: 10.1021/je500201y  0.32
2014 Christensen M, Wolf W, Freeman CM, Wimmer E, Adamson RB, Hallstadius L, Cantonwine PE, Mader EV. Effect of alloying elements on the properties of Zr and the Zr-H system Journal of Nuclear Materials. 445: 241-250. DOI: 10.1016/j.jnucmat.2013.10.040  0.32
2014 France-Lanord A, Rigby D, Mavromaras A, Eyert V, Saxe P, Freeman C, Wimmer E. MedeA®: Atomistic simulations for designing and testing materials for micro/nano electronics systems 2014 15th International Conference On Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, Eurosime 2014 0.32
2013 Li J, Lehmann S, Weißbecker B, Ojeda Naharros I, Schütz S, Joop G, Wimmer EA. Odoriferous Defensive stink gland transcriptome to identify novel genes necessary for quinone synthesis in the red flour beetle, Tribolium castaneum. Plos Genetics. 9: e1003596. PMID 23874211 DOI: 10.1371/journal.pgen.1003596  0.4
2013 Schaeper ND, Wimmer EA, Prpic NM. Appendage patterning in the primitively wingless hexapods Thermobia domestica (Zygentoma: Lepismatidae) and Folsomia candida (Collembola: Isotomidae). Development Genes and Evolution. 223: 341-50. PMID 23873479 DOI: 10.1007/s00427-013-0449-5  0.4
2013 Wimmer EA. Insect biotechnology: controllable replacement of disease vectors. Current Biology : Cb. 23: R453-6. PMID 23701690 DOI: 10.1016/j.cub.2013.03.058  0.4
2013 Yang C, Skiena S, Futcher B, Mueller S, Wimmer E. Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 9481-6. PMID 23690603 DOI: 10.1073/pnas.1307473110  1
2013 Scheible H, Laisney M, Wimmer E, Javornik A, Dolgos H. Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and human. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 1084-94. PMID 23627543 DOI: 10.3109/00498254.2013.791762  0.36
2013 Jahan N, Wimmer E, Mueller S. Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO). Plos One. 8: e60791. PMID 23593313 DOI: 10.1371/journal.pone.0060791  1
2013 Ogaugwu CE, Wimmer EA. Molecular cloning and expression of nanos in the Mediterranean fruit fly, Ceratitis capitata (Diptera: Tephritidae). Gene Expression Patterns : Gep. 13: 183-8. PMID 23567755 DOI: 10.1016/j.gep.2013.03.002  0.4
2013 Wimmer E. Profile of Eckard Wimmer. Interview by Sujata Gupta. Proceedings of the National Academy of Sciences of the United States of America. 110: 1973-5. PMID 23277540 DOI: 10.1073/pnas.1221558110  1
2013 Ogaugwu CE, Schetelig MF, Wimmer EA. Transgenic sexing system for Ceratitis capitata (Diptera: Tephritidae) based on female-specific embryonic lethality. Insect Biochemistry and Molecular Biology. 43: 1-8. PMID 23137881 DOI: 10.1016/j.ibmb.2012.10.010  0.4
2013 Christensen M, Eyert V, Freeman C, Wimmer E, Jain A, Blatchford J, Riley D, Shaw J. Formation of nickel-platinum silicides on a silicon substrate: Structure, phase stability, and diffusion from ab initio computations Journal of Applied Physics. 114. DOI: 10.1063/1.4816094  0.32
2013 McCloy JS, Wolf W, Wimmer E, Zelinski BJ. Impact of hydrogen and oxygen defects on the lattice parameter of chemical vapor deposited zinc sulfide Journal of Applied Physics. 113. DOI: 10.1063/1.4774078  0.32
2013 Soukiassian P, Wimmer E, Celasco E, Giallombardo C, Bonanni S, Vattuone L, Savio L, Tejeda A, Silly M, D'Angelo M, Sirotti F, Rocca M. Hydrogen-induced nanotunnel opening within semiconductor subsurface Nature Communications. 4. DOI: 10.1038/ncomms3800  0.32
2012 Song Y, Liu Y, Ward CB, Mueller S, Futcher B, Skiena S, Paul AV, Wimmer E. Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design. Proceedings of the National Academy of Sciences of the United States of America. 109: 14301-7. PMID 22886087 DOI: 10.1073/pnas.1211484109  1
2012 Wang C, Jiang P, Sand C, Paul AV, Wimmer E. Alanine scanning of poliovirus 2CATPase reveals new genetic evidence that capsid protein/2CATPase interactions are essential for morphogenesis. Journal of Virology. 86: 9964-75. PMID 22761387 DOI: 10.1128/JVI.00914-12  1
2012 Song Y, Paul AV, Wimmer E. Evolution of poliovirus defective interfering particles expressing Gaussia luciferase. Journal of Virology. 86: 1999-2010. PMID 22156535 DOI: 10.1128/JVI.05871-11  1
2012 Atlas R, Campbell P, Cozzarelli NR, Curfman G, Enquist L, Fink G, Flanagin A, Fletcher J, George E, Hammes G, Heyman D, Inglesby T, Kaplan S, Kennedy D, Krug J, ... ... Wimmer E, et al. Uncensored exchange of scientific results (Proceedings of the National Academy of Sciences (2003) 100, 4, (1464) DOI: 10.1073/pnas.0630491100) Proceedings of the National Academy of Sciences of the United States of America. 109: 8352. DOI: 10.1073/pnas.1206993109  1
2012 Hinkle CL, Galatage RV, Chapman RA, Vogel EM, Alshareef HN, Freeman C, Christensen M, Wimmer E, Niimi H, Li-Fatou A, Shaw JB, Chambers JJ. Gate-last TiN/HfO 2 band edge effective work functions using low-temperature anneals and selective cladding to control interface composition Applied Physics Letters. 100. DOI: 10.1063/1.3701165  0.32
2011 Ntini E, Wimmer EA. Second order regulator Collier directly controls intercalary-specific segment polarity gene expression. Developmental Biology. 360: 403-14. PMID 22005665 DOI: 10.1016/j.ydbio.2011.09.035  0.4
2011 Sitaraman V, Hearing P, Ward CB, Gnatenko DV, Wimmer E, Mueller S, Skiena S, Bahou WF. Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 108: 14294-9. PMID 21844368 DOI: 10.1073/pnas.1102883108  1
2011 Wimmer E, Paul AV. Synthetic poliovirus and other designer viruses: what have we learned from them? Annual Review of Microbiology. 65: 583-609. PMID 21756105 DOI: 10.1146/annurev-micro-090110-102957  1
2011 Mueller S, Wimmer E. Introducing recombinant picornaviral genomes into cells. Cold Spring Harbor Protocols. 2011: 657-63. PMID 21632780 DOI: 10.1101/pdb.prot5626  1
2011 Jahan N, Wimmer E, Mueller S. A host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO). Journal of Virology. 85: 7225-35. PMID 21561914 DOI: 10.1128/JVI.01804-09  1
2011 Chen B, Hrycaj S, Schinko JB, Podlaha O, Wimmer EA, Popadić A, Monteiro A. Pogostick: a new versatile piggyBac vector for inducible gene over-expression and down-regulation in emerging model systems. Plos One. 6: e18659. PMID 21533190 DOI: 10.1371/journal.pone.0018659  0.4
2011 Ntini E, Wimmer EA. Unique establishment of procephalic head segments is supported by the identification of cis-regulatory elements driving segment-specific segment polarity gene expression in Drosophila. Development Genes and Evolution. 221: 1-16. PMID 21399984 DOI: 10.1007/s00427-011-0354-8  0.4
2011 Toyoda H, Wimmer E, Cello J. Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo. International Journal of Oncology. 38: 81-7. PMID 21109928 DOI: 10.3892/ijo-00000826  1
2011 Schetelig MF, Götschel F, Viktorinová I, Handler AM, Wimmer EA. Recombination technologies for enhanced transgene stability in bioengineered insects. Genetica. 139: 71-8. PMID 20844938 DOI: 10.1007/s10709-010-9494-4  0.4
2011 Hinkle CL, Galatage RV, Chapman RA, Vogel EM, Alshareef HN, Freeman C, Wimmer E, Niimi H, Li-Fatou A, Chambers JJ, Shaw JB. Band-edge effective work functions by controlling HfO2/TiN interfacial composition for gate-last CMOS Ecs Transactions. 35: 285-295. DOI: 10.1149/1.3568871  0.32
2010 Wimmer E, Najafabadi R, Young GA, Ballard JD, Angeliu TM, Vollmer J, Chambers JJ, Niimi H, Shaw JB, Freeman C, Christensen M, Wolf W, Saxe P. Ab initio calculations for industrial materials engineering: successes and challenges. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 22: 384215. PMID 21386549 DOI: 10.1088/0953-8984/22/38/384215  0.32
2010 Tanaka I, Hafner J, Wimmer E, Asahi R. Selected contributions from the 3rd Theory Meets Industry International Workshop, TMI2009 (Nagoya, Japan, 11-13 November 2009). Journal of Physics. Condensed Matter : An Institute of Physics Journal. 22: 380301. PMID 21386363 DOI: 10.1088/0953-8984/22/38/380301  0.32
2010 Liu Y, Wang C, Mueller S, Paul AV, Wimmer E, Jiang P. Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis. Plos Pathogens. 6: e1001066. PMID 20865167 DOI: 10.1371/journal.ppat.1001066  1
2010 McDonald EC, Xie B, Workman M, Charlton-Perkins M, Terrell DA, Reischl J, Wimmer EA, Gebelein BA, Cook TA. Separable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events. Developmental Biology. 347: 122-32. PMID 20732315 DOI: 10.1016/j.ydbio.2010.08.016  0.4
2010 Mueller S, Coleman JR, Papamichail D, Ward CB, Nimnual A, Futcher B, Skiena S, Wimmer E. Live attenuated influenza virus vaccines by computer-aided rational design. Nature Biotechnology. 28: 723-6. PMID 20543832 DOI: 10.1038/nbt.1636  1
2010 Schinko JB, Weber M, Viktorinova I, Kiupakis A, Averof M, Klingler M, Wimmer EA, Bucher G. Functionality of the GAL4/UAS system in Tribolium requires the use of endogenous core promoters. Bmc Developmental Biology. 10: 53. PMID 20482875 DOI: 10.1186/1471-213X-10-53  0.4
2010 Schaeper ND, Pechmann M, Damen WG, Prpic NM, Wimmer EA. Evolutionary plasticity of collier function in head development of diverse arthropods. Developmental Biology. 344: 363-76. PMID 20457148 DOI: 10.1016/j.ydbio.2010.05.001  0.4
2010 Schaeper ND, Prpic NM, Wimmer EA. A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location. Bmc Evolutionary Biology. 10: 88. PMID 20353601 DOI: 10.1186/1471-2148-10-88  0.4
2010 Gallemann D, Wimmer E, Höfer CC, Freisleben A, Fluck M, Ladstetter B, Dolgos H. In vitro characterization of sarizotan metabolism: hepatic clearance, identification and characterization of metabolites, drug-metabolizing enzyme identification, and evaluation of cytochrome p450 inhibition. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 905-16. PMID 20219851 DOI: 10.1124/dmd.109.029835  0.36
2010 Hinkle CL, Galatage RV, Chapman RA, Vogel EM, Alshareef HN, Freeman C, Wimmer E, Niimi H, Li-Fatou A, Shaw JB, Chambers JJ. Dipole controlled metal gate with hybrid low resistivity cladding for gate-last CMOS with low Vt Digest of Technical Papers - Symposium On Vlsi Technology. 183-184. DOI: 10.1109/VLSIT.2010.5556220  0.32
2010 Mavromaras A, Rigby D, Wolf W, Christensen M, Halls M, Freeman C, Saxe P, Wimmer E. Computational materials engineering: Capabilities of atomic-scale prediction of mechanical, thermal, and electrical properties of microelectronic materials 2010 11th International Conference On Thermal, Mechanical and Multi-Physics Simulation, and Experiments in Microelectronics and Microsystems, Eurosime 2010. DOI: 10.1109/ESIME.2010.5464604  0.32
2010 Hinkle CL, Galatage RV, Chapman RA, Vogel EM, Alshareef HN, Freeman C, Wimmer E, Niimi H, Li-Fatou A, Shaw JB, Chambers JJ. Interfacial oxygen and nitrogen induced dipole formation and vacancy passivation for increased effective work functions in TiN/HfO2 gate stacks Applied Physics Letters. 96. DOI: 10.1063/1.3353993  0.32
2010 Christensen M, Angeliu TM, Ballard JD, Vollmer J, Najafabadi R, Wimmer E. Effect of impurity and alloying elements on Zr grain boundary strength from first-principles computations Journal of Nuclear Materials. 404: 121-127. DOI: 10.1016/j.jnucmat.2010.07.012  0.32
2009 Brown SJ, Shippy TD, Miller S, Bolognesi R, Beeman RW, Lorenzen MD, Bucher G, Wimmer EA, Klingler M. The red flour beetle, Tribolium castaneum (Coleoptera): a model for studies of development and pest biology. Cold Spring Harbor Protocols. 2009: pdb.emo126. PMID 20147228 DOI: 10.1101/pdb.emo126  0.4
2009 Wimmer E, Mueller S, Tumpey TM, Taubenberger JK. Synthetic viruses: a new opportunity to understand and prevent viral disease. Nature Biotechnology. 27: 1163-72. PMID 20010599 DOI: 10.1038/nbt.1593  1
2009 Castelló A, Franco D, Moral-López P, Berlanga JJ, Alvarez E, Wimmer E, Carrasco L. HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage. Plos One. 4: e7997. PMID 19956697 DOI: 10.1371/journal.pone.0007997  1
2009 Catteruccia F, Crisanti A, Wimmer EA. Transgenic technologies to induce sterility. Malaria Journal. 8: S7. PMID 19917077 DOI: 10.1186/1475-2875-8-S2-S7  0.4
2009 Trauner J, Schinko J, Lorenzen MD, Shippy TD, Wimmer EA, Beeman RW, Klingler M, Bucher G, Brown SJ. Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps. Bmc Biology. 7: 73. PMID 19891766 DOI: 10.1186/1741-7007-7-73  0.4
2009 Schetelig MF, Scolari F, Handler AM, Kittelmann S, Gasperi G, Wimmer EA. Site-specific recombination for the modification of transgenic strains of the Mediterranean fruit fly Ceratitis capitata. Proceedings of the National Academy of Sciences of the United States of America. 106: 18171-6. PMID 19828439 DOI: 10.1073/pnas.0907264106  0.4
2009 Liu Y, Wimmer E, Paul AV. Cis-acting RNA elements in human and animal plus-strand RNA viruses. Biochimica Et Biophysica Acta. 1789: 495-517. PMID 19781674 DOI: 10.1016/j.bbagrm.2009.09.007  1
2009 Schaeper ND, Prpic NM, Wimmer EA. A conserved function of the zinc finger transcription factor Sp8/9 in allometric appendage growth in the milkweed bug Oncopeltus fasciatus. Development Genes and Evolution. 219: 427-35. PMID 19760183 DOI: 10.1007/s00427-009-0301-0  0.4
2009 Kittelmann M, Schinko JB, Winkler M, Bucher G, Wimmer EA, Prpic NM. Insertional mutagenesis screening identifies the zinc finger homeodomain 2 (zfh2) gene as a novel factor required for embryonic leg development in Tribolium castaneum. Development Genes and Evolution. 219: 399-407. PMID 19760181 DOI: 10.1007/s00427-009-0303-y  0.4
2009 Li X, Mueller S, Wimmer E. Inhibition of hepatitis C virus IRES-mediated translation by oligonucleotides. Virus Research. 146: 29-35. PMID 19720092 DOI: 10.1016/j.virusres.2009.08.008  1
2009 Mueller S, Coleman JR, Wimmer E. Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis. Chemistry & Biology. 16: 337-47. PMID 19318214 DOI: 10.1016/j.chembiol.2009.03.002  1
2009 Schetelig MF, Caceres C, Zacharopoulou A, Franz G, Wimmer EA. Conditional embryonic lethality to improve the sterile insect technique in Ceratitis capitata (Diptera: Tephritidae). Bmc Biology. 7: 4. PMID 19173707 DOI: 10.1186/1741-7007-7-4  0.4
2009 Toegel JP, Wimmer EA, Prpic NM. Loss of spineless function transforms the Tribolium antenna into a thoracic leg with pretarsal, tibiotarsal, and femoral identity. Development Genes and Evolution. 219: 53-8. PMID 19030876 DOI: 10.1007/s00427-008-0265-5  0.4
2009 Paul AV, Belov GA, Ehrenfeld E, Wimmer E. Model of picornavirus RNA replication Viral Genome Replication. 3-23. DOI: 10.1007/b135974_1  1
2008 Wimmer E. Summary of workshop 'Theory Meets Industry'-the impact of ab initio solid state calculations on industrial materials research. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 20: 064243. PMID 21693904 DOI: 10.1088/0953-8984/20/6/064243  0.32
2008 Schetelig MF, Schmid BG, Zimowska G, Wimmer EA. Plasticity in mRNA expression and localization of orthodenticle within higher Diptera. Evolution & Development. 10: 700-4. PMID 19021740 DOI: 10.1111/j.1525-142X.2008.00283.x  0.4
2008 Zhang P, Mueller S, Morais MC, Bator CM, Bowman VD, Hafenstein S, Wimmer E, Rossmann MG. Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses. Proceedings of the National Academy of Sciences of the United States of America. 105: 18284-9. PMID 19011098 DOI: 10.1073/pnas.0807848105  1
2008 Coleman JR, Papamichail D, Skiena S, Futcher B, Wimmer E, Mueller S. Virus attenuation by genome-scale changes in codon pair bias. Science (New York, N.Y.). 320: 1784-7. PMID 18583614 DOI: 10.1126/science.1155761  1
2008 Scolari F, Schetelig MF, Bertin S, Malacrida AR, Gasperi G, Wimmer EA. Fluorescent sperm marking to improve the fight against the pest insect Ceratitis capitata (Wiedemann; Diptera: Tephritidae). New Biotechnology. 25: 76-84. PMID 18504022 DOI: 10.1016/j.nbt.2008.02.001  0.4
2008 Khan S, Peng X, Yin J, Zhang P, Wimmer E. Characterization of the New World monkey homologues of human poliovirus receptor CD155. Journal of Virology. 82: 7167-79. PMID 18480448 DOI: 10.1128/JVI.02664-07  1
2008 Schinko JB, Kreuzer N, Offen N, Posnien N, Wimmer EA, Bucher G. Divergent functions of orthodenticle, empty spiracles and buttonhead in early head patterning of the beetle Tribolium castaneum (Coleoptera). Developmental Biology. 317: 600-13. PMID 18407258 DOI: 10.1016/j.ydbio.2008.03.005  0.4
2008 Richert L, Tuschl G, Viollon-Abadie C, Blanchard N, Bonet A, Heyd B, Halkic N, Wimmer E, Dolgos H, Mueller SO. Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 702-14. PMID 18216275 DOI: 10.1124/dmd.107.018358  0.36
2008 Cello J, Toyoda H, Dejesus N, Dobrikova EY, Gromeier M, Wimmer E. Growth phenotypes and biosafety profiles in poliovirus-receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses. Journal of Medical Virology. 80: 352-9. PMID 18098139 DOI: 10.1002/jmv.21063  1
2008 Zemskova SM, Habeger CF, Paulson TE, Wimmer E, Mavromaras A, Kolmakov A. Sensors for environmental compliance of diesel engines Ecs Transactions. 16: 237-246. DOI: 10.1149/1.2981125  0.32
2008 Scolari F, Schetelig MF, Gabrieli P, Siciliano P, Gomulski LM, Karam N, Wimmer EA, Malacrida AR, Gasperi G. Insect transgenesis applied to tephritid pest control Journal of Applied Entomology. 132: 820-831. DOI: 10.1111/j.1439-0418.2008.01347.x  0.4
2008 Wimmer E, Wolf W, Sticht J, Saxe P, Geller CB, Najafabadi R, Young GA. Temperature-dependent diffusion coefficients from ab initio computations: Hydrogen, deuterium, and tritium in nickel Physical Review B - Condensed Matter and Materials Physics. 77. DOI: 10.1103/PhysRevB.77.134305  0.32
2008 Windiks R, Wimmer E, Pourovskii L, Biermann S, Georges A. Structure and optical properties of α- and γ-cerium sesquisulfide Journal of Alloys and Compounds. 459: 438-446. DOI: 10.1016/j.jallcom.2007.04.306  0.32
2007 Chumakov K, Ehrenfeld E, Wimmer E, Agol VI. Vaccination against polio should not be stopped. Nature Reviews. Microbiology. 5: 952-8. PMID 17965726 DOI: 10.1038/nrmicro1769  1
2007 Yin J, Liu Y, Wimmer E, Paul AV. Complete protein linkage map between the P2 and P3 non-structural proteins of poliovirus. The Journal of General Virology. 88: 2259-67. PMID 17622630 DOI: 10.1099/vir.0.82795-0  1
2007 Toyoda H, Franco D, Fujita K, Paul AV, Wimmer E. Replication of poliovirus requires binding of the poly(rC) binding protein to the cloverleaf as well as to the adjacent C-rich spacer sequence between the cloverleaf and the internal ribosomal entry site. Journal of Virology. 81: 10017-28. PMID 17609276 DOI: 10.1128/JVI.00516-07  1
2007 Jiang P, Faase JA, Toyoda H, Paul A, Wimmer E, Gorbalenya AE. Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradication. Proceedings of the National Academy of Sciences of the United States of America. 104: 9457-62. PMID 17517601 DOI: 10.1073/pnas.0700451104  1
2007 Fujita K, Krishnakumar SS, Franco D, Paul AV, London E, Wimmer E. Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication. Biochemistry. 46: 5185-99. PMID 17417822 DOI: 10.1021/bi6024758  1
2007 Toyoda H, Yin J, Mueller S, Wimmer E, Cello J. Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model. Cancer Research. 67: 2857-64. PMID 17363609 DOI: 10.1158/0008-5472.CAN-06-3713  1
2007 Liu Y, Franco D, Paul AV, Wimmer E. Tyrosine 3 of poliovirus terminal peptide VPg(3B) has an essential function in RNA replication in the context of its precursor protein, 3AB. Journal of Virology. 81: 5669-84. PMID 17360746 DOI: 10.1128/JVI.02350-06  1
2007 Viktorinová I, Wimmer EA. Comparative analysis of binary expression systems for directed gene expression in transgenic insects. Insect Biochemistry and Molecular Biology. 37: 246-54. PMID 17296499 DOI: 10.1016/j.ibmb.2006.11.010  0.4
2007 Schmitt MW, Von Landenberg F, Poth H, Wimmer E, Goddemeier T, Cavero I. Simple-to-use, reference criteria for revealing drug-induced QT interval prolongation in conscious dogs. European Journal of Pharmacology. 554: 46-52. PMID 17112506 DOI: 10.1016/j.ejphar.2006.09.056  0.36
2007 Tejeda A, Wimmer E, Soukiassian P, Dunham D, Rotenberg E, Denlinger JD, Michel EG. Atomic structure determination of the 3C -SiC(001) c (4×2) surface reconstruction: Experiment and theory Physical Review B - Condensed Matter and Materials Physics. 75. DOI: 10.1103/PhysRevB.75.195315  0.32
2007 Schetelig MF, Horn C, Handler AM, Wimmer EA. Development of an embryonic lethality system in Mediterranean fruit fly Ceratitis capitata Area-Wide Control of Insect Pests: From Research to Field Implementation. 85-93. DOI: 10.1007/978-1-4020-6059-5_6  0.4
2007 Mueller S, Coleman JR, Cello J, Paul A, Wimmer E, Papamichail D, Skiena S. Synthetic Biology: Synthesis and Modification of a Chemical Called Poliovirus Future Trends in Microelectronics: Up the Nano Creek. 113-121. DOI: 10.1002/9780470168264.ch11  1
2006 Ramos DM, Kamal F, Wimmer EA, Cartwright AN, Monteiro A. Temporal and spatial control of transgene expression using laser induction of the hsp70 promoter. Bmc Developmental Biology. 6: 55. PMID 17116248 DOI: 10.1186/1471-213X-6-55  0.4
2006 Mueller S, Papamichail D, Coleman JR, Skiena S, Wimmer E. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. Journal of Virology. 80: 9687-96. PMID 16973573 DOI: 10.1128/JVI.00738-06  1
2006 Lee H, Liu Y, Mejia E, Paul AV, Wimmer E. The C-terminal hydrophobic domain of hepatitis C virus RNA polymerase NS5B can be replaced with a heterologous domain of poliovirus protein 3A. Journal of Virology. 80: 11343-54. PMID 16971430 DOI: 10.1128/JVI.02072-05  1
2006 Wimmer E. The test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implications. Embo Reports. 7: S3-9. PMID 16819446 DOI: 10.1038/sj.embor.7400728  1
2006 Sarkar A, Atapattu A, Belikoff EJ, Heinrich JC, Li X, Horn C, Wimmer EA, Scott MJ. Insulated piggyBac vectors for insect transgenesis. Bmc Biotechnology. 6: 27. PMID 16776846 DOI: 10.1186/1472-6750-6-27  0.4
2006 Browne WE, Schmid BG, Wimmer EA, Martindale MQ. Expression of otd orthologs in the amphipod crustacean, Parhyale hawaiensis. Development Genes and Evolution. 216: 581-95. PMID 16773341 DOI: 10.1007/s00427-006-0074-7  0.4
2006 Cohn CA, Mueller S, Wimmer E, Leifer N, Greenbaum S, Strongin DR, Schoonen MA. Pyrite-induced hydroxyl radical formation and its effect on nucleic acids. Geochemical Transactions. 7: 3. PMID 16759350 DOI: 10.1186/1467-4866-7-3  1
2006 van Ooij MJ, Vogt DA, Paul A, Castro C, Kuijpers J, van Kuppeveld FJ, Cameron CE, Wimmer E, Andino R, Melchers WJ. Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. The Journal of General Virology. 87: 103-13. PMID 16361422 DOI: 10.1099/vir.0.81297-0  1
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86. PMID 16300678 DOI: 10.1186/1743-422X-2-86  1
2005 De Jesus N, Franco D, Paul A, Wimmer E, Cello J. Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence. Journal of Virology. 79: 14235-43. PMID 16254358 DOI: 10.1128/JVI.79.22.14235-14243.2005  1
2005 Wimmer EA. Insect transgenesis by site-specific recombination. Nature Methods. 2: 580-2. PMID 16094381 DOI: 10.1038/nmeth0805-580  0.4
2005 Xiao C, Bator-Kelly CM, Rieder E, Chipman PR, Craig A, Kuhn RJ, Wimmer E, Rossmann MG. The crystal structure of coxsackievirus A21 and its interaction with ICAM-1. Structure (London, England : 1993). 13: 1019-33. PMID 16004874 DOI: 10.1016/j.str.2005.04.011  1
2005 Johnson IS, Agol VI, Chumakov K, Ehrenfeld E, Wimmer E. Coordinating vaccine use is best way to combat polio [1] Nature. 435: 881. PMID 15959490  1
2005 Agol VI, Chumakov K, Ehrenfeld E, Wimmer E. Don't drop current vaccine until we have new ones. Nature. 435: 881. PMID 15959489 DOI: 10.1038/435881b  1
2005 Mueller S, Wimmer E, Cello J. Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event. Virus Research. 111: 175-93. PMID 15885840 DOI: 10.1016/j.virusres.2005.04.008  1
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67. PMID 15858019 DOI: 10.1128/JVI.79.10.6358-6367.2005  1
2005 Wimmer EA. Eco-friendly insect management. Nature Biotechnology. 23: 432-3. PMID 15815668 DOI: 10.1038/nbt0405-432  0.4
2005 Liang C, Rieder E, Hahm B, Jang SK, Paul A, Wimmer E. Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells. Virology. 333: 41-53. PMID 15708591 DOI: 10.1016/j.virol.2004.12.031  1
2005 Geller CB, Smith RW, Hack JE, Saxe P, Wimmer E. A computational search for ductilizing additives to Mo Scripta Materialia. 52: 205-210. DOI: 10.1016/j.scriptamat.2004.09.034  0.32
2005 Wolf W, Sticht J, Mavromaras A, Leblanc B, Saxe P, Wimmer E. Vibrational properties and thermochemistry from first principles Materials Science- Poland. 23: 365-373.  0.32
2005 Wimmer E. The growing importance of computations in materials science. Current capabilities and perspectives Materials Science- Poland. 23: 325-345.  0.32
2005 Wimmer E. The growing importance of computations in materials science: Current capabilities and perspectives Solid State Phenomena. 106: 168.  0.32
2004 Lee H, Shin H, Wimmer E, Paul AV. cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome. Journal of Virology. 78: 10865-77. PMID 15452207 DOI: 10.1128/JVI.78.20.10865-10877.2004  1
2004 Choi K, Kim JH, Li X, Paek KY, Ha SH, Ryu SH, Wimmer E, Jang SK. Identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotides. Nucleic Acids Research. 32: 1308-17. PMID 14981151 DOI: 10.1093/nar/gkh300  1
2004 Bergermayer W, Schweiger H, Wimmer E. Ab initio thermodynamics of oxide surfaces: O2 on Fe 2O3(0001) Physical Review B - Condensed Matter and Materials Physics. 69: 195409-1-195409-12. DOI: 10.1103/PhysRevB.69.195409  0.32
2003 Scheuner D, Gromeier M, Davies MV, Dorner AJ, Song B, Patel RV, Wimmer EJ, McLendon RE, Kaufman RJ. The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis. Virology. 317: 263-74. PMID 14698665 DOI: 10.1016/j.virol.2003.08.010  1
2003 Paul AV, Yin J, Mugavero J, Rieder E, Liu Y, Wimmer E. A "slide-back" mechanism for the initiation of protein-primed RNA synthesis by the RNA polymerase of poliovirus. The Journal of Biological Chemistry. 278: 43951-60. PMID 12937178 DOI: 10.1074/jbc.M307441200  1
2003 Rieder E, Xiang W, Paul A, Wimmer E. Analysis of the cloverleaf element in a human rhinovirus type 14/poliovirus chimera: correlation of subdomain D structure, ternary protein complex formation and virus replication. The Journal of General Virology. 84: 2203-16. PMID 12867653 DOI: 10.1099/vir.0.19013-0  1
2003 Hacker U, Nystedt S, Barmchi MP, Horn C, Wimmer EA. piggyBac-based insertional mutagenesis in the presence of stably integrated P elements in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 100: 7720-5. PMID 12802016 DOI: 10.1073/pnas.1230526100  0.4
2003 Mueller S, Rosenquist TA, Takai Y, Bronson RA, Wimmer E. Loss of nectin-2 at Sertoli-spermatid junctions leads to male infertility and correlates with severe spermatozoan head and midpiece malformation, impaired binding to the zona pellucida, and oocyte penetration. Biology of Reproduction. 69: 1330-40. PMID 12801998 DOI: 10.1095/biolreprod.102.014670  1
2003 Mueller S, Wimmer E. Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains. The Journal of Biological Chemistry. 278: 31251-60. PMID 12759359 DOI: 10.1074/jbc.M304166200  1
2003 Yin J, Paul AV, Wimmer E, Rieder E. Functional dissection of a poliovirus cis-acting replication element [PV-cre(2C)]: analysis of single- and dual-cre viral genomes and proteins that bind specifically to PV-cre RNA. Journal of Virology. 77: 5152-66. PMID 12692218 DOI: 10.1128/JVI.77.9.5152-5166.2003  1
2003 He Y, Mueller S, Chipman PR, Bator CM, Peng X, Bowman VD, Mukhopadhyay S, Wimmer E, Kuhn RJ, Rossmann MG. Complexes of poliovirus serotypes with their common cellular receptor, CD155. Journal of Virology. 77: 4827-35. PMID 12663789 DOI: 10.1128/JVI.77.8.4827-4835.2003  1
2003 Horn C, Offen N, Nystedt S, Häcker U, Wimmer EA. piggyBac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics. Genetics. 163: 647-61. PMID 12618403  0.4
2003 Wimmer EA. Innovations: applications of insect transgenesis. Nature Reviews. Genetics. 4: 225-32. PMID 12610527 DOI: 10.1038/nrg1021  0.4
2003 Atlas R, Campbell P, Cozzarelli NR, Curfman G, Enquist L, Fink G, Flanagin A, Fletcher J, George E, Hammes G, Heyman D, Inglesby T, Kaplan S, Kennedy D, Krug J, ... ... Wimmer E, et al. Statement on scientific publication and security. Science (New York, N.Y.). 299: 1149. PMID 12595658 DOI: 10.1126/science.299.5610.1149  1
2003 Paul AV, Peters J, Mugavero J, Yin J, van Boom JH, Wimmer E. Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. Journal of Virology. 77: 891-904. PMID 12502805  0.92
2002 Cello J, Paul AV, Wimmer E. Vaccines should be kept even if polio is wiped out. Nature. 418: 915. PMID 12198515 DOI: 10.1038/418915a  1
2002 Iwasaki A, Welker R, Mueller S, Linehan M, Nomoto A, Wimmer E. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection. The Journal of Infectious Diseases. 186: 585-92. PMID 12195344 DOI: 10.1086/342682  1
2002 Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y. Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions. Current Biology : Cb. 12: 1145-50. PMID 12121624 DOI: 10.1016/S0960-9822(02)00922-3  1
2002 Cello J, Paul AV, Wimmer E. Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template. Science (New York, N.Y.). 297: 1016-8. PMID 12114528 DOI: 10.1126/science.1072266  1
2002 Yang Y, Rijnbrand R, McKnight KL, Wimmer E, Paul A, Martin A, Lemon SM. Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14. Journal of Virology. 76: 7485-94. PMID 12097561 DOI: 10.1128/JVI.76.15.7485-7494.2002  1
2002 Verlinden Y, Cuconati A, Wimmer E, Rombau B. The viral protein 3CD induces an equilibrium between the viral protein and RNA synthesis in a cell-free system for poliovirus replication. Archives of Virology. 147: 731-44. PMID 12038684 DOI: 10.1007/s007050200022  1
2002 Ito J, Ghosh A, Moreira LA, Wimmer EA, Jacobs-Lorena M. Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite. Nature. 417: 452-5. PMID 12024215 DOI: 10.1038/417452a  0.4
2002 Solecki DJ, Gromeier M, Mueller S, Bernhardt G, Wimmer E. Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. The Journal of Biological Chemistry. 277: 25697-702. PMID 11983699 DOI: 10.1074/jbc.M201378200  1
2002 Lozovsky ER, Nurminsky D, Wimmer EA, Hartl DL. Unexpected stability of mariner transgenes in Drosophila. Genetics. 160: 527-35. PMID 11861559  0.4
2002 Pfister T, Feng H, Wimmer E, Jones KW. Synchrotron radiation-induced X-ray emission to identify metal ions in preparations of purified protein. Biotechniques. 32: 134-6, 138, 140-1. PMID 11808687  1
2002 Mueller S, Cao X, Welker R, Wimmer E. Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis. The Journal of Biological Chemistry. 277: 7897-904. PMID 11751937 DOI: 10.1074/jbc.M111937200  1
2002 Xiao C, Bator CM, Chipman P, Baker TS, Kuhn RJ, Wimmer E, Craig A, Rossmann MG. Pseudo-atomic structure of coxsackievirus A21 complexed with its cellular receptor, ICAM-1 Microscopy and Microanalysis. 8: 822-823.  1
2001 Chumakov K, Dragunsky E, Ivshina A, Enterline J, Wells V, Nomura T, Gromeier M, Wimmer E. Inactivated vaccines based on alternatives to wild-type seed virus. Developments in Biologicals. 105: 171-7. PMID 11763325  1
2001 Rieder E, Gorbalenya AE, Xiao C, He Y, Baker TS, Kuhn RJ, Rossmann MG, Wimmer E. Will the polio niche remain vacant? Developments in Biologicals. 105: 111-22; discussion 1. PMID 11763320  1
2001 Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M, ... ... Wimmer E, et al. New ways of initiating translation in eukaryotes. Molecular and Cellular Biology. 21: 8238-46. PMID 11710333 DOI: 10.1128/MCB.21.23.8238-8246.2001  1
2001 Gromeier M, Wimmer E. Viruses for the treatment of malignant glioma. Current Opinion in Molecular Therapeutics. 3: 503-8. PMID 11699896  1
2001 Gerber K, Wimmer E, Paul AV. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro). Journal of Virology. 75: 10979-90. PMID 11602738 DOI: 10.1128/JVI.75.22.10979-10990.2001  1
2001 Gerber K, Wimmer E, Paul AV. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: purification and enzymatic analysis of the RNA-dependent RNA polymerase 3D(pol). Journal of Virology. 75: 10969-78. PMID 11602737 DOI: 10.1128/JVI.75.22.10969-10978.2001  1
2001 Lange R, Peng X, Wimmer E, Lipp M, Bernhardt G. The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin. Virology. 285: 218-27. PMID 11437656 DOI: 10.1006/viro.2001.0943  1
2001 Hediger M, Niessen M, Wimmer EA, Dübendorfer A, Bopp D. Genetic transformation of the housefly Musca domestica with the lepidopteran derived transposon piggyBac. Insect Molecular Biology. 10: 113-9. PMID 11422506 DOI: 10.1046/j.1365-2583.2001.00243.x  0.4
2001 Zhao WD, Wimmer E. Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus. Journal of Virology. 75: 3719-30. PMID 11264361 DOI: 10.1128/JVI.75.8.3719-3730.2001  1
2001 Li X, Lu HH, Mueller S, Wimmer E. The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage. The Journal of General Virology. 82: 397-408. PMID 11161279  1
2001 Xiao C, Bator CM, Bowman VD, Rieder E, He Y, Hébert B, Bella J, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of coxsackievirus A21 with its cellular receptor, ICAM-1. Journal of Virology. 75: 2444-51. PMID 11160747 DOI: 10.1128/JVI.75.5.2444-2451.2001  1
2001 Pfister T, Wimmer E. Polypeptide p41 of a Norwalk-like virus is a nucleic acid-independent nucleoside triphosphatase. Journal of Virology. 75: 1611-9. PMID 11160659 DOI: 10.1128/JVI.75.4.1611-1619.2001  1
2000 Mui R, Lee CT, Candia T, Joyce J, Wimmer E. O17. The development of 'time release' nail enamels. International Journal of Cosmetic Science. 22: 121-31. PMID 18503467 DOI: 10.1046/j.1467-2494.2000.00005.x  0.4
2000 Verlinden Y, Cuconati A, Wimmer E, Rombaut B. The antiviral compound 5-(3,4-dichlorophenyl) methylhydantoin inhibits the post-synthetic cleavages and the assembly of poliovirus in a cell-free system. Antiviral Research. 48: 61-9. PMID 11080541 DOI: 10.1016/S0166-3542(00)00119-4  1
2000 Rieder E, Paul AV, Kim DW, van Boom JH, Wimmer E. Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation. Journal of Virology. 74: 10371-80. PMID 11044081 DOI: 10.1128/JVI.74.22.10371-10380.2000  1
2000 Paul AV, Rieder E, Kim DW, van Boom JH, Wimmer E. Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. Journal of Virology. 74: 10359-70. PMID 11044080 DOI: 10.1128/JVI.74.22.10359-10370.2000  1
2000 Verlinden Y, Cuconati A, Wimmer E, Rombaut B. Cell-free synthesis of poliovirus: 14S subunits are the key intermediates in the encapsidation of poliovirus RNA. The Journal of General Virology. 81: 2751-4. PMID 11038388  1
2000 Schaeffer V, Killian D, Desplan C, Wimmer EA. High bicoid levels render the terminal system dispensable for Drosophila head development. Development (Cambridge, England). 127: 3993-9. PMID 10952897  0.4
2000 Gromeier M, Solecki D, Patel DD, Wimmer E. Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. Virology. 273: 248-57. PMID 10915595 DOI: 10.1006/viro.2000.0418  1
2000 Paul AV, Mugavero J, Yin J, Hobson S, Schultz S, van Boom JH, Wimmer E. Studies on the attenuation phenotype of polio vaccines: poliovirus RNA polymerase derived from Sabin type 1 sequence is temperature sensitive in the uridylylation of VPg. Virology. 272: 72-84. PMID 10873750 DOI: 10.1006/viro.2000.0354  1
2000 Zhao WD, Lahser FC, Wimmer E. Genetic analysis of a poliovirus/hepatitis C virus (HCV) chimera: interaction between the poliovirus cloverleaf and a sequence in the HCV 5' nontranslated region results in a replication phenotype. Journal of Virology. 74: 6223-6. PMID 10846111 DOI: 10.1128/JVI.74.13.6223-6226.2000  1
2000 Gromeier M, Lachmann S, Rosenfeld MR, Gutin PH, Wimmer E. Intergeneric poliovirus recombinants for the treatment of malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 97: 6803-8. PMID 10841575 DOI: 10.1073/pnas.97.12.6803  1
2000 Schöck F, Reischl J, Wimmer E, Taubert H, Purnell BA, Jäckle H. Phenotypic suppression of empty spiracles is prevented by buttonhead. Nature. 405: 351-4. PMID 10830964 DOI: 10.1038/35012620  0.4
2000 Solecki D, Bernhardt G, Lipp M, Wimmer E. Identification of a nuclear respiratory factor-1 binding site within the core promoter of the human polio virus receptor/CD155 gene. The Journal of Biological Chemistry. 275: 12453-62. PMID 10777530  0.56
2000 Rossmann MG, Bella J, Kolatkar PR, He Y, Wimmer E, Kuhn RJ, Baker TS. Cell recognition and entry by rhino- and enteroviruses. Virology. 269: 239-47. PMID 10753702 DOI: 10.1006/viro.2000.0258  1
2000 Wimmer EA, Carleton A, Harjes P, Turner T, Desplan C. Bicoid-independent formation of thoracic segments in Drosophila. Science (New York, N.Y.). 287: 2476-9. PMID 10741965 DOI: 10.1126/science.287.5462.2476  0.4
2000 He Y, Bowman VD, Mueller S, Bator CM, Bella J, Peng X, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of the poliovirus receptor with poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 97: 79-84. PMID 10618374 DOI: 10.1073/pnas.97.1.79  1
2000 Pfister T, Jones KW, Wimmer E. A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. Journal of Virology. 74: 334-43. PMID 10590122  0.36
1999 Schöck F, Purnell BA, Wimmer EA, Jäckle H. Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead. Mechanisms of Development. 89: 125-32. PMID 10559487 DOI: 10.1016/S0925-4773(99)00215-4  0.4
1999 Agol VI, Paul AV, Wimmer E. Paradoxes of the replication of picornaviral genomes. Virus Research. 62: 129-47. PMID 10507323  0.92
1999 Duggal R, Wimmer E. Genetic recombination of poliovirus in vitro and in vivo: temperature-dependent alteration of crossover sites. Virology. 258: 30-41. PMID 10329565 DOI: 10.1006/viro.1999.9703  1
1999 Schaeffer V, Janody F, Loss C, Desplan C, Wimmer EA. Bicoid functions without its TATA-binding protein-associated factor interaction domains. Proceedings of the National Academy of Sciences of the United States of America. 96: 4461-6. PMID 10200284 DOI: 10.1073/pnas.96.8.4461  0.4
1999 Pfister T, Wimmer E. Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication. The Journal of Biological Chemistry. 274: 6992-7001. PMID 10066753  0.36
1999 Zhao WD, Wimmer E, Lahser FC. Poliovirus/Hepatitis C virus (internal ribosomal entry site-core) chimeric viruses: improved growth properties through modification of a proteolytic cleavage site and requirement for core RNA sequences but not for core-related polypeptides. Journal of Virology. 73: 1546-54. PMID 9882360  1
1999 Gromeier M, Bossert B, Arita M, Nomoto A, Wimmer E. Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence. Journal of Virology. 73: 958-64. PMID 9882296  1
1999 Solecki D, Wimmer E, Lipp M, Bernhardt G. Identification and characterization of the cis-acting elements of the human CD155 gene core promoter. The Journal of Biological Chemistry. 274: 1791-800. PMID 9880562  0.56
1998 Solecki D, Gromeier M, Harber J, Bernhardt G, Wimmer E. Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction. Journal of Molecular Recognition : Jmr. 11: 2-9. PMID 10076797 DOI: 10.1002/(SICI)1099-1352(199812)11:1/6<2::AID-JMR380>3.0.CO;2-D  1
1998 Paul AV, Mugavero J, Molla A, Wimmer E. Internal ribosomal entry site scanning of the poliovirus polyprotein: implications for proteolytic processing. Virology. 250: 241-53. PMID 9770438 DOI: 10.1006/viro.1998.9376  0.92
1998 Xiang W, Cuconati A, Hope D, Kirkegaard K, Wimmer E. Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB. Journal of Virology. 72: 6732-41. PMID 9658121  0.64
1998 Cuconati A, Molla A, Wimmer E. Brefeldin A inhibits cell-free, de novo synthesis of poliovirus. Journal of Virology. 72: 6456-64. PMID 9658088  0.64
1998 Paul AV, van Boom JH, Filippov D, Wimmer E. Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature. 393: 280-4. PMID 9607767 DOI: 10.1038/30529  1
1998 Gromeier M, Wimmer E. Mechanism of injury-provoked poliomyelitis. Journal of Virology. 72: 5056-60. PMID 9573275  1
1998 Cuconati A, Xiang W, Lahser F, Pfister T, Wimmer E. A protein linkage map of the P2 nonstructural proteins of poliovirus. Journal of Virology. 72: 1297-307. PMID 9445030  0.64
1998 Mueller S, Wimmer E. Expression of foreign proteins by poliovirus polyprotein fusion: analysis of genetic stability reveals rapid deletions and formation of cardioviruslike open reading frames. Journal of Virology. 72: 20-31. PMID 9420196  1
1997 Vorbrüggen G, Constien R, Zilian O, Wimmer EA, Dowe G, Taubert H, Noll M, Jäckle H. Embryonic expression and characterization of a Ptx1 homolog in Drosophila. Mechanisms of Development. 68: 139-47. PMID 9431811 DOI: 10.1016/S0925-4773(97)00139-1  0.4
1997 Duggal R, Cuconati A, Gromeier M, Wimmer E. Genetic recombination of poliovirus in a cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 94: 13786-91. PMID 9391105 DOI: 10.1073/pnas.94.25.13786  1
1997 Gromeier M, Mueller S, Solecki D, Bossert B, Bernhardt G, Wimmer E. Determinants of poliovirus neurovirulence. Journal of Neurovirology. 3: S35-8. PMID 9179789  1
1997 Wimmer EA, Cohen SM, Jäckle H, Desplan C. buttonhead does not contribute to a combinatorial code proposed for Drosophila head development. Development (Cambridge, England). 124: 1509-17. PMID 9108367  0.4
1997 Solecki D, Schwarz S, Wimmer E, Lipp M, Bernhardt G. The promoters for human and monkey poliovirus receptors. Requirements for basic and cell type-specific activity. The Journal of Biological Chemistry. 272: 5579-86. PMID 9038165  0.56
1996 Hahm B, Back SH, Lee TG, Wimmer E, Jang SK. Generation of a novel poliovirus with a requirement of hepatitis C virus protease NS3 activity. Virology. 226: 318-26. PMID 8955051 DOI: 10.1006/viro.1996.0659  1
1996 Wimmer EA, Frommer G, Purnell BA, Jäckle H. buttonhead and D-Sp1: a novel Drosophila gene pair. Mechanisms of Development. 59: 53-62. PMID 8892232 DOI: 10.1016/0925-4773(96)00575-8  0.4
1996 Lu HH, Wimmer E. Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 93: 1412-7. PMID 8643645  0.84
1996 Gromeier M, Alexander L, Wimmer E. Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants. Proceedings of the National Academy of Sciences of the United States of America. 93: 2370-5. PMID 8637880 DOI: 10.1073/pnas.93.6.2370  1
1996 Yalamanchili P, Harris K, Wimmer E, Dasgupta A. Inhibition of basal transcription by poliovirus: a virus- encoded protease (3Cpro) inhibits formation of TBP-TATA box complex in vitro. Journal of Virology. 70: 2922-9. PMID 8627767  1
1996 Cao X, Wimmer E. Genetic variation of the poliovirus genome with two VPg coding units. The Embo Journal. 15: 23-33. PMID 8598203  0.84
1995 Wimmer EA, Simpson-Brose M, Cohen SM, Desplan C, Jäckle H. Trans- and cis-acting requirements for blastodermal expression of the head gap gene buttonhead. Mechanisms of Development. 53: 235-45. PMID 8562425 DOI: 10.1016/0925-4773(95)00439-8  0.4
1995 Witherell GW, Schultz-Witherell CS, Wimmer E. Cis-acting elements of the encephalomyocarditis virus internal ribosomal entry site. Virology. 214: 660-3. PMID 8553572 DOI: 10.1006/viro.1995.0081  0.92
1995 Harber J, Bernhardt G, Lu HH, Sgro JY, Wimmer E. Canyon rim residues, including antigenic determinants, modulate serotype-specific binding of polioviruses to mutants of the poliovirus receptor. Virology. 214: 559-70. PMID 8553558 DOI: 10.1006/viro.1995.0067  0.84
1995 Xiang W, Cuconati A, Paul AV, Cao X, Wimmer E. Molecular dissection of the multifunctional poliovirus RNA-binding protein 3AB. Rna (New York, N.Y.). 1: 892-904. PMID 8548654  0.92
1995 Cao X, Wimmer E. Intragenomic complementation of a 3AB mutant in dicistronic polioviruses. Virology. 209: 315-26. PMID 7778266 DOI: 10.1006/viro.1995.1263  0.84
1995 Xiang W, Harris KS, Alexander L, Wimmer E. Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication. Journal of Virology. 69: 3658-67. PMID 7745714  1
1995 Gromeier M, Lu HH, Bernhardt G, Harber JJ, Bibb JA, Wimmer E. The human poliovirus receptor. Receptor-virus interaction and parameters of disease specificity. Annals of the New York Academy of Sciences. 753: 19-36. PMID 7611627 DOI: 10.1111/j.1749-6632.1995.tb27528.x  1
1995 Hellen CU, Wimmer E. Translation of encephalomyocarditis virus RNA by internal ribosomal entry. Current Topics in Microbiology and Immunology. 203: 31-63. PMID 7555090  0.64
1995 Lu HH, Alexander L, Wimmer E. Construction and genetic analysis of dicistronic polioviruses containing open reading frames for epitopes of human immunodeficiency virus type 1 gp120. Journal of Virology. 69: 4797-806. PMID 7541843  0.84
1995 Lu HH, Li X, Cuconati A, Wimmer E. Analysis of picornavirus 2A(pro) proteins: separation of proteinase from translation and replication functions. Journal of Virology. 69: 7445-52. PMID 7494250  1
1995 Gromeier M, Lu HH, Wimmer E. Mouse neuropathogenic poliovirus strains cause damage in the central nervous system distinct from poliomyelitis. Microbial Pathogenesis. 18: 253-67. PMID 7476091 DOI: 10.1016/S0882-4010(05)80002-6  1
1994 Hellen CU, Pestova TV, Litterst M, Wimmer E. The cellular polypeptide p57 (pyrimidine tract-binding protein) binds to multiple sites in the poliovirus 5' nontranslated region. Journal of Virology. 68: 941-50. PMID 8289396  0.64
1994 Lama J, Paul AV, Harris KS, Wimmer E. Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as co-factor for RNA polymerase 3Dpol. The Journal of Biological Chemistry. 269: 66-70. PMID 8276867  1
1994 Bibb JA, Witherell G, Bernhardt G, Wimmer E. Interaction of poliovirus with its cell surface binding site. Virology. 201: 107-15. PMID 8178474 DOI: 10.1006/viro.1994.1270  1
1994 Witherell GW, Wimmer E. Encephalomyocarditis virus internal ribosomal entry site RNA-protein interactions. Journal of Virology. 68: 3183-92. PMID 8151781  0.92
1994 Paul AV, Molla A, Wimmer E. Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C. Virology. 199: 188-99. PMID 8116242 DOI: 10.1006/viro.1994.1111  0.92
1994 Bernhardt G, Bibb JA, Bradley J, Wimmer E. Molecular characterization of the cellular receptor for poliovirus. Virology. 199: 105-13. PMID 8116232 DOI: 10.1006/viro.1994.1102  1
1994 Hellen CU, Pestova TV, Wimmer E. Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis. Journal of Virology. 68: 6312-22. PMID 8083971  0.64
1994 González-Gaitán M, Rothe M, Wimmer EA, Taubert H, Jäckle H. Redundant functions of the genes knirps and knirps-related for the establishment of anterior Drosophila head structures. Proceedings of the National Academy of Sciences of the United States of America. 91: 8567-71. PMID 8078924  0.4
1994 Bibb JA, Bernhardt G, Wimmer E. The human poliovirus receptor alpha is a serine phosphoprotein. Journal of Virology. 68: 6111-5. PMID 8057492  1
1994 Bibb JA, Bernhardt G, Wimmer E. Cleavage site of the poliovirus receptor signal sequence. The Journal of General Virology. 75: 1875-81. PMID 8046389  1
1994 Schmid M, Wimmer E. IRES-controlled protein synthesis and genome replication of poliovirus. Archives of Virology. Supplementum. 9: 279-89. PMID 8032259  1
1994 Paul AV, Cao X, Harris KS, Lama J, Wimmer E. Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB. The Journal of Biological Chemistry. 269: 29173-81. PMID 7961883  1
1994 Pestova TV, Hellen CU, Wimmer E. A conserved AUG triplet in the 5' nontranslated region of poliovirus can function as an initiation codon in vitro and in vivo. Virology. 204: 729-37. PMID 7941341 DOI: 10.1006/viro.1994.1588  0.64
1994 Lu HH, Yang CF, Murdin AD, Klein MH, Harber JJ, Kew OM, Wimmer E. Mouse neurovirulence determinants of poliovirus type 1 strain LS-a map to the coding regions of capsid protein VP1 and proteinase 2Apro. Journal of Virology. 68: 7507-15. PMID 7933134  0.84
1994 Molla A, Harris KS, Paul AV, Shin SH, Mugavero J, Wimmer E. Stimulation of poliovirus proteinase 3Cpro-related proteolysis by the genome-linked protein VPg and its precursor 3AB. The Journal of Biological Chemistry. 269: 27015-20. PMID 7929442  1
1994 Harris KS, Xiang W, Alexander L, Lane WS, Paul AV, Wimmer E. Interaction of poliovirus polypeptide 3CDpro with the 5' and 3' termini of the poliovirus genome. Identification of viral and cellular cofactors needed for efficient binding. The Journal of Biological Chemistry. 269: 27004-14. PMID 7929441  0.92
1994 Rothe M, Wimmer EA, Pankratz MJ, González-Gaitán M, Jäckle H. Identical transacting factor requirement for knirps and knirps-related Gene expression in the anterior but not in the posterior region of the Drosophila embryo. Mechanisms of Development. 46: 169-81. PMID 7918102 DOI: 10.1016/0925-4773(94)90069-8  0.4
1994 Bernhardt G, Harber J, Zibert A, deCrombrugghe M, Wimmer E. The poliovirus receptor: identification of domains and amino acid residues critical for virus binding. Virology. 203: 344-56. PMID 7914388 DOI: 10.1006/viro.1994.1493  0.56
1994 Alexander L, Lu HH, Gromeier M, Wimmer E. Dicistronic polioviruses as expression vectors for foreign genes. Aids Research and Human Retroviruses. 10: S57-60. PMID 7865334  1
1994 Alexander L, Lu HH, Wimmer E. Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 1406-10. PMID 7509072  0.84
1993 Molla A, Paul AV, Schmid M, Jang SK, Wimmer E. Studies on dicistronic polioviruses implicate viral proteinase 2Apro in RNA replication. Virology. 196: 739-47. PMID 8396807 DOI: 10.1006/viro.1993.1531  1
1993 Molla A, Paul AV, Wimmer E. Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system. Journal of Virology. 67: 5932-8. PMID 8396661  0.92
1993 Hellen CU, Witherell GW, Schmid M, Shin SH, Pestova TV, Gil A, Wimmer E. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 90: 7642-6. PMID 8395052  1
1993 Cao X, Kuhn RJ, Wimmer E. Replication of poliovirus RNA containing two VPg coding sequences leads to a specific deletion event. Journal of Virology. 67: 5572-8. PMID 8394461  0.84
1993 Witherell GW, Gil A, Wimmer E. Interaction of polypyrimidine tract binding protein with the encephalomyocarditis virus mRNA internal ribosomal entry site. Biochemistry. 32: 8268-75. PMID 8394133  0.92
1993 Molla A, Hellen CU, Wimmer E. Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteinases by elastase-specific inhibitors. Journal of Virology. 67: 4688-95. PMID 8392608  0.64
1993 Tucker SP, Thornton CL, Wimmer E, Compans RW. Vectorial release of poliovirus from polarized human intestinal epithelial cells. Journal of Virology. 67: 4274-82. PMID 8389927  1
1993 Molla A, Paul AV, Wimmer E. In vitro synthesis of poliovirus. Developments in Biological Standardization. 78: 39-53. PMID 8388831  0.92
1993 Wimmer EA, Jäckle H, Pfeifle C, Cohen SM. A Drosophila homologue of human Sp1 is a head-specific segmentation gene. Nature. 366: 690-4. PMID 8259212 DOI: 10.1038/366690a0  0.4
1993 Wimmer E, Hellen CU, Cao X. Genetics of poliovirus. Annual Review of Genetics. 27: 353-436. PMID 8122908 DOI: 10.1146/annurev.ge.27.120193.002033  0.84
1993 Wimmer E, Nomoto A. Molecular biology and cell-free synthesis of poliovirus. Biologicals : Journal of the International Association of Biological Standardization. 21: 349-56. PMID 8024750 DOI: 10.1006/biol.1993.1095  0.4
1992 Hellen CU, Wimmer E. The role of proteolytic processing in the morphogenesis of virus particles. Experientia. 48: 201-15. PMID 1740191  0.64
1992 Murdin AD, Lu HH, Murray MG, Wimmer E. Poliovirus antigenic hybrids simultaneously expressing antigenic determinants from all three serotypes. The Journal of General Virology. 73: 607-11. PMID 1372037  0.84
1992 Hellen CU, Wimmer E. Viral proteases as targets for chemotherapeutic intervention. Current Opinion in Biotechnology. 3: 643-9. PMID 1369416  0.64
1992 Harris KS, Reddigari SR, Nicklin MJ, Hämmerle T, Wimmer E. Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase. Journal of Virology. 66: 7481-9. PMID 1331532  1
1992 Hämmerle T, Molla A, Wimmer E. Mutational analysis of the proposed FG loop of poliovirus proteinase 3C identifies amino acids that are necessary for 3CD cleavage and might be determinants of a function distinct from proteolytic activity. Journal of Virology. 66: 6028-34. PMID 1326654  0.32
1992 Hellen CU, Lee CK, Wimmer E. Determinants of substrate recognition by poliovirus 2A proteinase. Journal of Virology. 66: 3330-8. PMID 1316450  0.96
1992 Molla A, Jang SK, Paul AV, Reuer Q, Wimmer E. Cardioviral internal ribosomal entry site is functional in a genetically engineered dicistronic poliovirus. Nature. 356: 255-7. PMID 1313153 DOI: 10.1038/356255a0  0.92
1992 Hellen CU, Wimmer E. Maturation of poliovirus capsid proteins. Virology. 187: 391-7. PMID 1312265  0.64
1991 Hämmerle T, Hellen CU, Wimmer E. Site-directed mutagenesis of the putative catalytic triad of poliovirus 3C proteinase. The Journal of Biological Chemistry. 266: 5412-6. PMID 1848550  0.64
1991 Harber JJ, Bradley J, Anderson CW, Wimmer E. Catalysis of poliovirus VP0 maturation cleavage is not mediated by serine 10 of VP2. Journal of Virology. 65: 326-34. PMID 1845893  1
1991 Murdin AD, Mirzayan C, Kameda A, Wimmer E. The effect of site and mode of expression of a heterologous antigenic determinant on the properties of poliovirus hybrids. Microbial Pathogenesis. 10: 27-37. PMID 1713280 DOI: 10.1016/0882-4010(91)90063-G  1
1991 Partin K, Wimmer E, Carter C. Mutational analysis of a native substrate of the HIV-1 proteinase. Advances in Experimental Medicine and Biology. 306: 503-6. PMID 1667451  1
1991 Molla A, Paul AV, Wimmer E. Cell-free, de novo synthesis of poliovirus. Science (New York, N.Y.). 254: 1647-51. PMID 1661029  0.92
1991 Pestova TV, Hellen CU, Wimmer E. Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein. Journal of Virology. 65: 6194-204. PMID 1656091  0.64
1991 Altmeyer R, Murdin AD, Harber JJ, Wimmer E. Construction and characterization of a poliovirus/rhinovirus antigenic hybrid. Virology. 184: 636-44. PMID 1653493  0.44
1991 Murdin AD, Kameda A, Murray MG, Wimmer E. Phenotypic characterization of antigenic hybrids of poliovirus. Microbial Pathogenesis. 10: 39-45. PMID 1649944 DOI: 10.1016/0882-4010(91)90064-H  1
1991 Hellen CU, Fäcke M, Kräusslich HG, Lee CK, Wimmer E. Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220. Journal of Virology. 65: 4226-31. PMID 1649327  0.96
1991 Partin K, Zybarth G, Ehrlich L, DeCrombrugghe M, Wimmer E, Carter C. Deletion of sequences upstream of the proteinase improves the proteolytic processing of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 88: 4776-80. PMID 1647017  1
1990 Partin K, Kräusslich HG, Ehrlich L, Wimmer E, Carter C. Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase. Journal of Virology. 64: 3938-47. PMID 2196384  1
1990 Jang SK, Wimmer E. Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes & Development. 4: 1560-72. PMID 2174810  0.64
1990 Murdin AD, Murray MG, Wimmer E. Novel approaches to picornavirus vaccines. Advances in Biotechnological Processes. 14: 301-23. PMID 2171555  0.44
1990 Reuer Q, Kuhn RJ, Wimmer E. Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg. Journal of Virology. 64: 2967-75. PMID 2159557  0.52
1990 Ehrlich LS, Krausslich HG, Wimmer E, Carter CA. Expression in Escherichia coli and purification of human immunodeficiency virus type 1 capsid protein (p24). Aids Research and Human Retroviruses. 6: 1169-75. PMID 2123631  1
1990 Jang SK, Pestova TV, Hellen CU, Witherell GW, Wimmer E. Cap-independent translation of picornavirus RNAs: structure and function of the internal ribosomal entry site. Enzyme. 44: 292-309. PMID 1966843  0.92
1989 Hellen CU, Kräusslich HG, Wimmer E. Proteolytic processing of polyproteins in the replication of RNA viruses. Biochemistry. 28: 9881-90. PMID 2695162  0.64
1989 Jang SK, Davies MV, Kaufman RJ, Wimmer E. Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo. Journal of Virology. 63: 1651-60. PMID 2538648  0.64
1989 Mendelsohn CL, Wimmer E, Racaniello VR. Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell. 56: 855-65. PMID 2538245 DOI: 10.1016/0092-8674(89)90690-9  1
1989 Hellen CU, de Crombrugghe M, Wimmer E, Seeger MA, Kaufman TC. Amalgamated sequences. Nature. 340: 682. PMID 2505084 DOI: 10.1038/340682a0  0.64
1989 Murdin AD, Wimmer E. Construction of a poliovirus type 1/type 2 antigenic hybrid by manipulation of neutralization antigenic site II. Journal of Virology. 63: 5251-7. PMID 2479772  0.44
1988 Kräusslich HG, Schneider H, Zybarth G, Carter CA, Wimmer E. Processing of in vitro-synthesized gag precursor proteins of human immunodeficiency virus (HIV) type 1 by HIV proteinase generated in Escherichia coli. Journal of Virology. 62: 4393-7. PMID 3050149  1
1988 Nicklin MJ, Harris KS, Pallai PV, Wimmer E. Poliovirus proteinase 3C: large-scale expression, purification, and specific cleavage activity on natural and synthetic substrates in vitro. Journal of Virology. 62: 4586-93. PMID 2846872  1
1988 Lee CK, Wimmer E. Proteolytic processing of poliovirus polyprotein: elimination of 2Apro-mediated, alternative cleavage of polypeptide 3CD by in vitro mutagenesis. Virology. 166: 405-14. PMID 2845654  0.96
1988 Kuhn RJ, Tada H, Ypma-Wong MF, Semler BL, Wimmer E. Mutational analysis of the genome-linked protein VPg of poliovirus. Journal of Virology. 62: 4207-15. PMID 2845132  1
1988 Jang SK, Kräusslich HG, Nicklin MJ, Duke GM, Palmenberg AC, Wimmer E. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. Journal of Virology. 62: 2636-43. PMID 2839690  0.64
1988 Murray MG, Bradley J, Yang XF, Wimmer E, Moss EG, Racaniello VR. Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I. Science (New York, N.Y.). 241: 213-5. PMID 2838906  1
1988 Murray MG, Kuhn RJ, Arita M, Kawamura N, Nomoto A, Wimmer E. Poliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys. Proceedings of the National Academy of Sciences of the United States of America. 85: 3203-7. PMID 2834736  0.52
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