| Year |
Citation |
Score |
| 2021 |
Wang Y, Yang C, Song Y, Coleman JR, Stawowczyk M, Tafrova J, Tasker S, Boltz D, Baker R, Garcia L, Seale O, Kushnir A, Wimmer E, Mueller S. Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34193524 DOI: 10.1073/pnas.2102775118 |
0.511 |
|
| 2021 |
Le Nouën C, McCarty T, Yang L, Brown M, Wimmer E, Collins PL, Buchholz UJ. Rescue of codon-pair deoptimized respiratory syncytial virus by the emergence of genomes with very large internal deletions that complemented replication. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33753491 DOI: 10.1073/pnas.2020969118 |
0.32 |
|
| 2019 |
Le Nouën C, Luongo CL, Yang L, Mueller S, Wimmer E, DiNapoli JM, Collins PL, Buchholz UJ. Optimization of the codon-pair usage of human respiratory syncytial virus paradoxically resulted in reduced viral replication and reduced immunogenicity. Journal of Virology. PMID 31666376 DOI: 10.1128/Jvi.01296-19 |
0.636 |
|
| 2019 |
Stauft CB, Song Y, Gorbatsevych O, Pantoja P, Rodriguez IV, Futcher B, Sariol CA, Wimmer E. Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2. Virology. 537: 237-245. PMID 31539771 DOI: 10.1016/J.Virol.2019.09.003 |
0.345 |
|
| 2019 |
Song Y, Mugavero J, Stauft CB, Wimmer E. Dengue and Zika Virus 5' Untranslated Regions Harbor Internal Ribosomal Entry Site Functions. Mbio. 10. PMID 30967466 DOI: 10.1128/Mbio.00459-19 |
0.462 |
|
| 2018 |
Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E. Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes. Plos One. 13: e0198303. PMID 30192757 DOI: 10.1371/Journal.Pone.0198303 |
0.614 |
|
| 2017 |
Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E. Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973853 DOI: 10.1073/Pnas.1714385114 |
0.666 |
|
| 2017 |
Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, et al. Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049853 DOI: 10.1073/Pnas.1619242114 |
0.606 |
|
| 2016 |
Asare E, Mugavero J, Jiang P, Wimmer E, Paul AV. A single amino acid substitution in the nonstructural protein 2CATPase of poliovirus causes conditional defects in encapsidation and uncoating. Journal of Virology. PMID 27076638 DOI: 10.1128/Jvi.02877-15 |
0.551 |
|
| 2016 |
Sanders BP, de Los Rios Oakes I, van Hoek V, Bockstal V, Kamphuis T, Uil TG, Song Y, Cooper G, Crawt LE, Martín J, Zahn R, Lewis J, Wimmer E, Custers JH, Schuitemaker H, et al. Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine. Plos Pathogens. 12: e1005483. PMID 27032093 DOI: 10.1371/Journal.Ppat.1005483 |
0.357 |
|
| 2015 |
Broadbent AJ, Santos CP, Anafu A, Wimmer E, Mueller S, Subbarao K. Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets. Vaccine. PMID 26655630 DOI: 10.1016/J.Vaccine.2015.11.054 |
0.577 |
|
| 2015 |
Futcher B, Gorbatsevych O, Shen SH, Stauft CB, Song Y, Wang B, Leatherwood J, Gardin J, Yurovsky A, Mueller S, Wimmer E. Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished. Proceedings of the National Academy of Sciences of the United States of America. 112: E3635-6. PMID 26071446 DOI: 10.1073/Pnas.1507710112 |
0.532 |
|
| 2015 |
Wang B, Yang C, Tekes G, Mueller S, Paul A, Whelan SP, Wimmer E. Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate. Mbio. 6. PMID 25827413 DOI: 10.1128/Mbio.00237-15 |
0.614 |
|
| 2015 |
Shen SH, Stauft CB, Gorbatsevych O, Song Y, Ward CB, Yurovsky A, Mueller S, Futcher B, Wimmer E. Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference. Proceedings of the National Academy of Sciences of the United States of America. 112: 4749-54. PMID 25825721 DOI: 10.1073/Pnas.1502864112 |
0.599 |
|
| 2015 |
Chen YH, Du W, Hagemeijer MC, Takvorian PM, Pau C, Cali A, Brantner CA, Stempinski ES, Connelly PS, Ma HC, Jiang P, Wimmer E, Altan-Bonnet G, Altan-Bonnet N. Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses. Cell. 160: 619-30. PMID 25679758 DOI: 10.1016/J.Cell.2015.01.032 |
0.49 |
|
| 2015 |
Paul AV, Wimmer E. Initiation of protein-primed picornavirus RNA synthesis. Virus Research. 206: 12-26. PMID 25592245 DOI: 10.1016/J.Virusres.2014.12.028 |
0.416 |
|
| 2014 |
Jiang P, Liu Y, Ma HC, Paul AV, Wimmer E. Picornavirus morphogenesis. Microbiology and Molecular Biology Reviews : Mmbr. 78: 418-37. PMID 25184560 DOI: 10.1128/MMBR.00012-14 |
0.473 |
|
| 2014 |
Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proceedings of the National Academy of Sciences of the United States of America. 111: 13169-74. PMID 25157129 DOI: 10.1073/pnas.1411290111 |
0.544 |
|
| 2014 |
Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E. Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation. The Journal of General Virology. 95: 1668-76. PMID 24784416 DOI: 10.1099/Vir.0.064535-0 |
0.304 |
|
| 2014 |
Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Binding of glutathione to enterovirus capsids is essential for virion morphogenesis. Plos Pathogens. 10: e1004039. PMID 24722756 DOI: 10.1371/Journal.Ppat.1004039 |
0.545 |
|
| 2014 |
Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P. An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. Plos Pathogens. 10: e1004052. PMID 24722315 DOI: 10.1371/Journal.Ppat.1004052 |
0.743 |
|
| 2014 |
Wang C, Ma HC, Wimmer E, Jiang P, Paul AV. A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis. The Journal of General Virology. 95: 1255-65. PMID 24558221 DOI: 10.1099/Vir.0.062497-0 |
0.634 |
|
| 2014 |
Shen SH, Futcher B, Yang C, Wimmer E. Synthetic Biology Approaches for Vaccine Development Reviews in Cell Biology and Molecular Medicine. 1-27. DOI: 10.1002/3527600906.Mcb.20120059 |
0.348 |
|
| 2013 |
Yang C, Skiena S, Futcher B, Mueller S, Wimmer E. Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 9481-6. PMID 23690603 DOI: 10.1073/Pnas.1307473110 |
0.548 |
|
| 2013 |
Jahan N, Wimmer E, Mueller S. Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO). Plos One. 8: e60791. PMID 23593313 DOI: 10.1371/Journal.Pone.0060791 |
0.689 |
|
| 2012 |
Song Y, Liu Y, Ward CB, Mueller S, Futcher B, Skiena S, Paul AV, Wimmer E. Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design. Proceedings of the National Academy of Sciences of the United States of America. 109: 14301-7. PMID 22886087 DOI: 10.1073/Pnas.1211484109 |
0.609 |
|
| 2012 |
Wang C, Jiang P, Sand C, Paul AV, Wimmer E. Alanine scanning of poliovirus 2CATPase reveals new genetic evidence that capsid protein/2CATPase interactions are essential for morphogenesis. Journal of Virology. 86: 9964-75. PMID 22761387 DOI: 10.1128/Jvi.00914-12 |
0.653 |
|
| 2012 |
Song Y, Paul AV, Wimmer E. Evolution of poliovirus defective interfering particles expressing Gaussia luciferase. Journal of Virology. 86: 1999-2010. PMID 22156535 DOI: 10.1128/Jvi.05871-11 |
0.369 |
|
| 2011 |
Sitaraman V, Hearing P, Ward CB, Gnatenko DV, Wimmer E, Mueller S, Skiena S, Bahou WF. Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 108: 14294-9. PMID 21844368 DOI: 10.1073/Pnas.1102883108 |
0.585 |
|
| 2011 |
Wimmer E, Paul AV. Synthetic poliovirus and other designer viruses: what have we learned from them? Annual Review of Microbiology. 65: 583-609. PMID 21756105 DOI: 10.1146/Annurev-Micro-090110-102957 |
0.399 |
|
| 2011 |
Mueller S, Wimmer E. Introducing recombinant picornaviral genomes into cells. Cold Spring Harbor Protocols. 2011: 657-63. PMID 21632780 DOI: 10.1101/Pdb.Prot5626 |
0.533 |
|
| 2011 |
Jahan N, Wimmer E, Mueller S. A host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO). Journal of Virology. 85: 7225-35. PMID 21561914 DOI: 10.1128/Jvi.01804-09 |
0.665 |
|
| 2010 |
Liu Y, Wang C, Mueller S, Paul AV, Wimmer E, Jiang P. Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis. Plos Pathogens. 6: e1001066. PMID 20865167 DOI: 10.1371/Journal.Ppat.1001066 |
0.744 |
|
| 2010 |
Mueller S, Coleman JR, Papamichail D, Ward CB, Nimnual A, Futcher B, Skiena S, Wimmer E. Live attenuated influenza virus vaccines by computer-aided rational design. Nature Biotechnology. 28: 723-6. PMID 20543832 DOI: 10.1038/Nbt.1636 |
0.563 |
|
| 2009 |
Wimmer E, Mueller S, Tumpey TM, Taubenberger JK. Synthetic viruses: a new opportunity to understand and prevent viral disease. Nature Biotechnology. 27: 1163-72. PMID 20010599 DOI: 10.1038/Nbt.1593 |
0.585 |
|
| 2009 |
Liu Y, Wimmer E, Paul AV. Cis-acting RNA elements in human and animal plus-strand RNA viruses. Biochimica Et Biophysica Acta. 1789: 495-517. PMID 19781674 DOI: 10.1016/J.Bbagrm.2009.09.007 |
0.42 |
|
| 2009 |
Li X, Mueller S, Wimmer E. Inhibition of hepatitis C virus IRES-mediated translation by oligonucleotides. Virus Research. 146: 29-35. PMID 19720092 DOI: 10.1016/J.Virusres.2009.08.008 |
0.589 |
|
| 2009 |
Mueller S, Coleman JR, Wimmer E. Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis. Chemistry & Biology. 16: 337-47. PMID 19318214 DOI: 10.1016/J.Chembiol.2009.03.002 |
0.585 |
|
| 2008 |
Zhang P, Mueller S, Morais MC, Bator CM, Bowman VD, Hafenstein S, Wimmer E, Rossmann MG. Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses. Proceedings of the National Academy of Sciences of the United States of America. 105: 18284-9. PMID 19011098 DOI: 10.1073/Pnas.0807848105 |
0.596 |
|
| 2008 |
Coleman JR, Papamichail D, Skiena S, Futcher B, Wimmer E, Mueller S. Virus attenuation by genome-scale changes in codon pair bias. Science (New York, N.Y.). 320: 1784-7. PMID 18583614 DOI: 10.1126/Science.1155761 |
0.573 |
|
| 2008 |
Khan S, Peng X, Yin J, Zhang P, Wimmer E. Characterization of the New World monkey homologues of human poliovirus receptor CD155. Journal of Virology. 82: 7167-79. PMID 18480448 DOI: 10.1128/Jvi.02664-07 |
0.524 |
|
| 2008 |
Richert L, Tuschl G, Viollon-Abadie C, Blanchard N, Bonet A, Heyd B, Halkic N, Wimmer E, Dolgos H, Mueller SO. Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 702-14. PMID 18216275 DOI: 10.1124/dmd.107.018358 |
0.439 |
|
| 2008 |
Cello J, Toyoda H, Dejesus N, Dobrikova EY, Gromeier M, Wimmer E. Growth phenotypes and biosafety profiles in poliovirus-receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses. Journal of Medical Virology. 80: 352-9. PMID 18098139 DOI: 10.1002/Jmv.21063 |
0.355 |
|
| 2008 |
Li X, Mueller S, Wimmer E. S1933 The Difference of Hepatitis C Viral (HCV) Internal Ribosomal Entry Site (Ires) and Picornaviral Ires-Mediated Translation Inhibited By Oligonucleotides Gastroenterology. 134: A-787. DOI: 10.1016/S0016-5085(08)63675-6 |
0.591 |
|
| 2007 |
Yin J, Liu Y, Wimmer E, Paul AV. Complete protein linkage map between the P2 and P3 non-structural proteins of poliovirus. The Journal of General Virology. 88: 2259-67. PMID 17622630 DOI: 10.1099/Vir.0.82795-0 |
0.561 |
|
| 2007 |
Toyoda H, Franco D, Fujita K, Paul AV, Wimmer E. Replication of poliovirus requires binding of the poly(rC) binding protein to the cloverleaf as well as to the adjacent C-rich spacer sequence between the cloverleaf and the internal ribosomal entry site. Journal of Virology. 81: 10017-28. PMID 17609276 DOI: 10.1128/Jvi.00516-07 |
0.443 |
|
| 2007 |
Jiang P, Faase JA, Toyoda H, Paul A, Wimmer E, Gorbalenya AE. Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradication. Proceedings of the National Academy of Sciences of the United States of America. 104: 9457-62. PMID 17517601 DOI: 10.1073/Pnas.0700451104 |
0.49 |
|
| 2007 |
Fujita K, Krishnakumar SS, Franco D, Paul AV, London E, Wimmer E. Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication. Biochemistry. 46: 5185-99. PMID 17417822 DOI: 10.1021/Bi6024758 |
0.35 |
|
| 2007 |
Toyoda H, Yin J, Mueller S, Wimmer E, Cello J. Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model. Cancer Research. 67: 2857-64. PMID 17363609 DOI: 10.1158/0008-5472.Can-06-3713 |
0.63 |
|
| 2007 |
Liu Y, Franco D, Paul AV, Wimmer E. Tyrosine 3 of poliovirus terminal peptide VPg(3B) has an essential function in RNA replication in the context of its precursor protein, 3AB. Journal of Virology. 81: 5669-84. PMID 17360746 DOI: 10.1128/Jvi.02350-06 |
0.461 |
|
| 2007 |
Mueller S, Coleman JR, Cello J, Paul A, Wimmer E, Papamichail D, Skiena S. Synthetic Biology: Synthesis and Modification of a Chemical Called Poliovirus Future Trends in Microelectronics: Up the Nano Creek. 113-121. DOI: 10.1002/9780470168264.ch11 |
0.429 |
|
| 2006 |
Mueller S, Papamichail D, Coleman JR, Skiena S, Wimmer E. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. Journal of Virology. 80: 9687-96. PMID 16973573 DOI: 10.1128/Jvi.00738-06 |
0.64 |
|
| 2006 |
Lee H, Liu Y, Mejia E, Paul AV, Wimmer E. The C-terminal hydrophobic domain of hepatitis C virus RNA polymerase NS5B can be replaced with a heterologous domain of poliovirus protein 3A. Journal of Virology. 80: 11343-54. PMID 16971430 DOI: 10.1128/Jvi.02072-05 |
0.682 |
|
| 2006 |
Wimmer E. The test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implications. Embo Reports. 7: S3-9. PMID 16819446 DOI: 10.1038/Sj.Embor.7400728 |
0.328 |
|
| 2006 |
Cohn CA, Mueller S, Wimmer E, Leifer N, Greenbaum S, Strongin DR, Schoonen MA. Pyrite-induced hydroxyl radical formation and its effect on nucleic acids. Geochemical Transactions. 7: 3. PMID 16759350 DOI: 10.1186/1467-4866-7-3 |
0.478 |
|
| 2006 |
van Ooij MJ, Vogt DA, Paul A, Castro C, Kuijpers J, van Kuppeveld FJ, Cameron CE, Wimmer E, Andino R, Melchers WJ. Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. The Journal of General Virology. 87: 103-13. PMID 16361422 DOI: 10.1099/Vir.0.81297-0 |
0.425 |
|
| 2005 |
Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86. PMID 16300678 DOI: 10.1186/1743-422X-2-86 |
0.455 |
|
| 2005 |
De Jesus N, Franco D, Paul A, Wimmer E, Cello J. Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence. Journal of Virology. 79: 14235-43. PMID 16254358 DOI: 10.1128/Jvi.79.22.14235-14243.2005 |
0.422 |
|
| 2005 |
Xiao C, Bator-Kelly CM, Rieder E, Chipman PR, Craig A, Kuhn RJ, Wimmer E, Rossmann MG. The crystal structure of coxsackievirus A21 and its interaction with ICAM-1. Structure (London, England : 1993). 13: 1019-33. PMID 16004874 DOI: 10.1016/J.Str.2005.04.011 |
0.543 |
|
| 2005 |
Mueller S, Wimmer E, Cello J. Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event. Virus Research. 111: 175-93. PMID 15885840 DOI: 10.1016/J.Virusres.2005.04.008 |
0.528 |
|
| 2005 |
Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67. PMID 15858019 DOI: 10.1128/Jvi.79.10.6358-6367.2005 |
0.467 |
|
| 2005 |
Liang C, Rieder E, Hahm B, Jang SK, Paul A, Wimmer E. Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells. Virology. 333: 41-53. PMID 15708591 DOI: 10.1016/J.Virol.2004.12.031 |
0.531 |
|
| 2004 |
Lee H, Shin H, Wimmer E, Paul AV. cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome. Journal of Virology. 78: 10865-77. PMID 15452207 DOI: 10.1128/Jvi.78.20.10865-10877.2004 |
0.771 |
|
| 2004 |
Choi K, Kim JH, Li X, Paek KY, Ha SH, Ryu SH, Wimmer E, Jang SK. Identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotides. Nucleic Acids Research. 32: 1308-17. PMID 14981151 DOI: 10.1093/Nar/Gkh300 |
0.438 |
|
| 2003 |
Paul AV, Yin J, Mugavero J, Rieder E, Liu Y, Wimmer E. A "slide-back" mechanism for the initiation of protein-primed RNA synthesis by the RNA polymerase of poliovirus. The Journal of Biological Chemistry. 278: 43951-60. PMID 12937178 DOI: 10.1074/Jbc.M307441200 |
0.579 |
|
| 2003 |
Rieder E, Xiang W, Paul A, Wimmer E. Analysis of the cloverleaf element in a human rhinovirus type 14/poliovirus chimera: correlation of subdomain D structure, ternary protein complex formation and virus replication. The Journal of General Virology. 84: 2203-16. PMID 12867653 DOI: 10.1099/Vir.0.19013-0 |
0.441 |
|
| 2003 |
Mueller S, Rosenquist TA, Takai Y, Bronson RA, Wimmer E. Loss of nectin-2 at Sertoli-spermatid junctions leads to male infertility and correlates with severe spermatozoan head and midpiece malformation, impaired binding to the zona pellucida, and oocyte penetration. Biology of Reproduction. 69: 1330-40. PMID 12801998 DOI: 10.1095/Biolreprod.102.014670 |
0.528 |
|
| 2003 |
Mueller S, Wimmer E. Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains. The Journal of Biological Chemistry. 278: 31251-60. PMID 12759359 DOI: 10.1074/Jbc.M304166200 |
0.522 |
|
| 2003 |
Yin J, Paul AV, Wimmer E, Rieder E. Functional dissection of a poliovirus cis-acting replication element [PV-cre(2C)]: analysis of single- and dual-cre viral genomes and proteins that bind specifically to PV-cre RNA. Journal of Virology. 77: 5152-66. PMID 12692218 DOI: 10.1128/Jvi.77.9.5152-5166.2003 |
0.598 |
|
| 2003 |
He Y, Mueller S, Chipman PR, Bator CM, Peng X, Bowman VD, Mukhopadhyay S, Wimmer E, Kuhn RJ, Rossmann MG. Complexes of poliovirus serotypes with their common cellular receptor, CD155. Journal of Virology. 77: 4827-35. PMID 12663789 DOI: 10.1128/Jvi.77.8.4827-4835.2003 |
0.682 |
|
| 2003 |
Paul AV, Peters J, Mugavero J, Yin J, van Boom JH, Wimmer E. Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. Journal of Virology. 77: 891-904. PMID 12502805 DOI: 10.1128/Jvi.77.2.891-904.2003 |
0.56 |
|
| 2002 |
Iwasaki A, Welker R, Mueller S, Linehan M, Nomoto A, Wimmer E. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection. The Journal of Infectious Diseases. 186: 585-92. PMID 12195344 DOI: 10.1086/342682 |
0.518 |
|
| 2002 |
Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y. Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions. Current Biology : Cb. 12: 1145-50. PMID 12121624 DOI: 10.1016/S0960-9822(02)00922-3 |
0.505 |
|
| 2002 |
Cello J, Paul AV, Wimmer E. Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template. Science (New York, N.Y.). 297: 1016-8. PMID 12114528 DOI: 10.1126/Science.1072266 |
0.446 |
|
| 2002 |
Yang Y, Rijnbrand R, McKnight KL, Wimmer E, Paul A, Martin A, Lemon SM. Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14. Journal of Virology. 76: 7485-94. PMID 12097561 DOI: 10.1128/Jvi.76.15.7485-7494.2002 |
0.44 |
|
| 2002 |
Verlinden Y, Cuconati A, Wimmer E, Rombau B. The viral protein 3CD induces an equilibrium between the viral protein and RNA synthesis in a cell-free system for poliovirus replication. Archives of Virology. 147: 731-44. PMID 12038684 DOI: 10.1007/S007050200022 |
0.452 |
|
| 2002 |
Solecki DJ, Gromeier M, Mueller S, Bernhardt G, Wimmer E. Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. The Journal of Biological Chemistry. 277: 25697-702. PMID 11983699 DOI: 10.1074/Jbc.M201378200 |
0.514 |
|
| 2002 |
Mueller S, Cao X, Welker R, Wimmer E. Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis. The Journal of Biological Chemistry. 277: 7897-904. PMID 11751937 DOI: 10.1074/Jbc.M111937200 |
0.547 |
|
| 2001 |
Gerber K, Wimmer E, Paul AV. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro). Journal of Virology. 75: 10979-90. PMID 11602738 DOI: 10.1128/Jvi.75.22.10979-10990.2001 |
0.413 |
|
| 2001 |
Gerber K, Wimmer E, Paul AV. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: purification and enzymatic analysis of the RNA-dependent RNA polymerase 3D(pol). Journal of Virology. 75: 10969-78. PMID 11602737 DOI: 10.1128/Jvi.75.22.10969-10978.2001 |
0.403 |
|
| 2001 |
Zhao WD, Wimmer E. Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus. Journal of Virology. 75: 3719-30. PMID 11264361 DOI: 10.1128/Jvi.75.8.3719-3730.2001 |
0.383 |
|
| 2001 |
Li X, Lu HH, Mueller S, Wimmer E. The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage. The Journal of General Virology. 82: 397-408. PMID 11161279 DOI: 10.1099/0022-1317-82-2-397 |
0.635 |
|
| 2001 |
Xiao C, Bator CM, Bowman VD, Rieder E, He Y, Hébert B, Bella J, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of coxsackievirus A21 with its cellular receptor, ICAM-1. Journal of Virology. 75: 2444-51. PMID 11160747 DOI: 10.1128/Jvi.75.5.2444-2451.2001 |
0.316 |
|
| 2001 |
Pfister T, Wimmer E. Polypeptide p41 of a Norwalk-like virus is a nucleic acid-independent nucleoside triphosphatase. Journal of Virology. 75: 1611-9. PMID 11160659 DOI: 10.1128/Jvi.75.4.1611-1619.2001 |
0.401 |
|
| 2000 |
Verlinden Y, Cuconati A, Wimmer E, Rombaut B. The antiviral compound 5-(3,4-dichlorophenyl) methylhydantoin inhibits the post-synthetic cleavages and the assembly of poliovirus in a cell-free system. Antiviral Research. 48: 61-9. PMID 11080541 DOI: 10.1016/S0166-3542(00)00119-4 |
0.344 |
|
| 2000 |
Rieder E, Paul AV, Kim DW, van Boom JH, Wimmer E. Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation. Journal of Virology. 74: 10371-80. PMID 11044081 DOI: 10.1128/Jvi.74.22.10371-10380.2000 |
0.444 |
|
| 2000 |
Paul AV, Rieder E, Kim DW, van Boom JH, Wimmer E. Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. Journal of Virology. 74: 10359-70. PMID 11044080 DOI: 10.1128/Jvi.74.22.10359-10370.2000 |
0.42 |
|
| 2000 |
Verlinden Y, Cuconati A, Wimmer E, Rombaut B. Cell-free synthesis of poliovirus: 14S subunits are the key intermediates in the encapsidation of poliovirus RNA. The Journal of General Virology. 81: 2751-4. PMID 11038388 DOI: 10.1099/0022-1317-81-11-2751 |
0.377 |
|
| 2000 |
Paul AV, Mugavero J, Yin J, Hobson S, Schultz S, van Boom JH, Wimmer E. Studies on the attenuation phenotype of polio vaccines: poliovirus RNA polymerase derived from Sabin type 1 sequence is temperature sensitive in the uridylylation of VPg. Virology. 272: 72-84. PMID 10873750 DOI: 10.1006/Viro.2000.0354 |
0.558 |
|
| 2000 |
Zhao WD, Lahser FC, Wimmer E. Genetic analysis of a poliovirus/hepatitis C virus (HCV) chimera: interaction between the poliovirus cloverleaf and a sequence in the HCV 5' nontranslated region results in a replication phenotype. Journal of Virology. 74: 6223-6. PMID 10846111 DOI: 10.1128/Jvi.74.13.6223-6226.2000 |
0.354 |
|
| 2000 |
Gromeier M, Lachmann S, Rosenfeld MR, Gutin PH, Wimmer E. Intergeneric poliovirus recombinants for the treatment of malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 97: 6803-8. PMID 10841575 DOI: 10.1073/Pnas.97.12.6803 |
0.41 |
|
| 2000 |
Solecki D, Bernhardt G, Lipp M, Wimmer E. Identification of a nuclear respiratory factor-1 binding site within the core promoter of the human polio virus receptor/CD155 gene. The Journal of Biological Chemistry. 275: 12453-62. PMID 10777530 DOI: 10.1074/Jbc.275.17.12453 |
0.322 |
|
| 2000 |
Rossmann MG, Bella J, Kolatkar PR, He Y, Wimmer E, Kuhn RJ, Baker TS. Cell recognition and entry by rhino- and enteroviruses. Virology. 269: 239-47. PMID 10753702 DOI: 10.1006/Viro.2000.0258 |
0.364 |
|
| 2000 |
He Y, Bowman VD, Mueller S, Bator CM, Bella J, Peng X, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of the poliovirus receptor with poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 97: 79-84. PMID 10618374 DOI: 10.1073/Pnas.97.1.79 |
0.536 |
|
| 2000 |
Pfister T, Jones KW, Wimmer E. A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. Journal of Virology. 74: 334-43. PMID 10590122 DOI: 10.1128/Jvi.74.1.334-343.2000 |
0.456 |
|
| 1999 |
Agol VI, Paul AV, Wimmer E. Paradoxes of the replication of picornaviral genomes. Virus Research. 62: 129-47. PMID 10507323 DOI: 10.1016/S0168-1702(99)00037-4 |
0.441 |
|
| 1999 |
Duggal R, Wimmer E. Genetic recombination of poliovirus in vitro and in vivo: temperature-dependent alteration of crossover sites. Virology. 258: 30-41. PMID 10329565 DOI: 10.1006/Viro.1999.9703 |
0.44 |
|
| 1999 |
Pfister T, Wimmer E. Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication. The Journal of Biological Chemistry. 274: 6992-7001. PMID 10066753 DOI: 10.1074/Jbc.274.11.6992 |
0.365 |
|
| 1999 |
Zhao WD, Wimmer E, Lahser FC. Poliovirus/Hepatitis C virus (internal ribosomal entry site-core) chimeric viruses: improved growth properties through modification of a proteolytic cleavage site and requirement for core RNA sequences but not for core-related polypeptides. Journal of Virology. 73: 1546-54. PMID 9882360 DOI: 10.1128/Jvi.73.2.1546-1554.1999 |
0.396 |
|
| 1999 |
Gromeier M, Bossert B, Arita M, Nomoto A, Wimmer E. Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence. Journal of Virology. 73: 958-64. PMID 9882296 DOI: 10.1128/Jvi.73.2.958-964.1999 |
0.372 |
|
| 1998 |
Solecki D, Gromeier M, Harber J, Bernhardt G, Wimmer E. Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction. Journal of Molecular Recognition : Jmr. 11: 2-9. PMID 10076797 DOI: 10.1002/(Sici)1099-1352(199812)11:1/6<2::Aid-Jmr380>3.0.Co;2-D |
0.378 |
|
| 1998 |
Paul AV, Mugavero J, Molla A, Wimmer E. Internal ribosomal entry site scanning of the poliovirus polyprotein: implications for proteolytic processing. Virology. 250: 241-53. PMID 9770438 DOI: 10.1006/Viro.1998.9376 |
0.432 |
|
| 1998 |
Xiang W, Cuconati A, Hope D, Kirkegaard K, Wimmer E. Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB. Journal of Virology. 72: 6732-41. PMID 9658121 DOI: 10.1128/Jvi.72.8.6732-6741.1998 |
0.432 |
|
| 1998 |
Cuconati A, Molla A, Wimmer E. Brefeldin A inhibits cell-free, de novo synthesis of poliovirus. Journal of Virology. 72: 6456-64. PMID 9658088 DOI: 10.1128/Jvi.72.8.6456-6464.1998 |
0.388 |
|
| 1998 |
Paul AV, van Boom JH, Filippov D, Wimmer E. Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature. 393: 280-4. PMID 9607767 DOI: 10.1038/30529 |
0.412 |
|
| 1998 |
Cuconati A, Xiang W, Lahser F, Pfister T, Wimmer E. A protein linkage map of the P2 nonstructural proteins of poliovirus. Journal of Virology. 72: 1297-307. PMID 9445030 DOI: 10.1128/Jvi.72.2.1297-1307.1998 |
0.362 |
|
| 1998 |
Mueller S, Wimmer E. Expression of foreign proteins by poliovirus polyprotein fusion: analysis of genetic stability reveals rapid deletions and formation of cardioviruslike open reading frames. Journal of Virology. 72: 20-31. PMID 9420196 DOI: 10.1128/Jvi.72.1.20-31.1998 |
0.641 |
|
| 1997 |
Duggal R, Cuconati A, Gromeier M, Wimmer E. Genetic recombination of poliovirus in a cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 94: 13786-91. PMID 9391105 DOI: 10.1073/Pnas.94.25.13786 |
0.417 |
|
| 1997 |
Gromeier M, Mueller S, Solecki D, Bossert B, Bernhardt G, Wimmer E. Determinants of poliovirus neurovirulence. Journal of Neurovirology. 3: S35-8. PMID 9179789 |
0.428 |
|
| 1997 |
Solecki D, Schwarz S, Wimmer E, Lipp M, Bernhardt G. The promoters for human and monkey poliovirus receptors. Requirements for basic and cell type-specific activity. The Journal of Biological Chemistry. 272: 5579-86. PMID 9038165 DOI: 10.1074/Jbc.272.9.5579 |
0.342 |
|
| 1997 |
Xiang W, Paul AV, Wimmer E. RNA Signals in Entero- and Rhinovirus Genome Replication☆ Seminars in Virology. 8: 256-273. DOI: 10.1006/Smvy.1997.0128 |
0.412 |
|
| 1996 |
Hahm B, Back SH, Lee TG, Wimmer E, Jang SK. Generation of a novel poliovirus with a requirement of hepatitis C virus protease NS3 activity. Virology. 226: 318-26. PMID 8955051 DOI: 10.1006/Viro.1996.0659 |
0.306 |
|
| 1996 |
Gromeier M, Alexander L, Wimmer E. Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants. Proceedings of the National Academy of Sciences of the United States of America. 93: 2370-5. PMID 8637880 DOI: 10.1073/Pnas.93.6.2370 |
0.334 |
|
| 1995 |
Hovi T, Huovilainen A, Murdin A, Wimmer E. Isolation of escape mutants of a hybrid poliovirus with the aid of insert-specific polyclonal antibodies. The Journal of General Virology. 76: 1861-5. PMID 9049393 DOI: 10.1099/0022-1317-76-7-1861 |
0.417 |
|
| 1995 |
Witherell GW, Schultz-Witherell CS, Wimmer E. Cis-acting elements of the encephalomyocarditis virus internal ribosomal entry site. Virology. 214: 660-3. PMID 8553572 DOI: 10.1006/Viro.1995.0081 |
0.341 |
|
| 1995 |
Harber J, Bernhardt G, Lu HH, Sgro JY, Wimmer E. Canyon rim residues, including antigenic determinants, modulate serotype-specific binding of polioviruses to mutants of the poliovirus receptor. Virology. 214: 559-70. PMID 8553558 DOI: 10.1006/Viro.1995.0067 |
0.388 |
|
| 1995 |
Xiang W, Cuconati A, Paul AV, Cao X, Wimmer E. Molecular dissection of the multifunctional poliovirus RNA-binding protein 3AB. Rna (New York, N.Y.). 1: 892-904. PMID 8548654 |
0.356 |
|
| 1995 |
Cao X, Wimmer E. Intragenomic complementation of a 3AB mutant in dicistronic polioviruses. Virology. 209: 315-26. PMID 7778266 DOI: 10.1006/Viro.1995.1263 |
0.448 |
|
| 1995 |
Xiang W, Harris KS, Alexander L, Wimmer E. Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication. Journal of Virology. 69: 3658-67. PMID 7745714 DOI: 10.1128/Jvi.69.6.3658-3667.1995 |
0.451 |
|
| 1995 |
Gromeier M, Lu HH, Bernhardt G, Harber JJ, Bibb JA, Wimmer E. The human poliovirus receptor. Receptor-virus interaction and parameters of disease specificity. Annals of the New York Academy of Sciences. 753: 19-36. PMID 7611627 DOI: 10.1111/J.1749-6632.1995.Tb27528.X |
0.665 |
|
| 1995 |
Lu HH, Alexander L, Wimmer E. Construction and genetic analysis of dicistronic polioviruses containing open reading frames for epitopes of human immunodeficiency virus type 1 gp120. Journal of Virology. 69: 4797-806. PMID 7541843 DOI: 10.1128/Jvi.69.8.4797-4806.1995 |
0.396 |
|
| 1994 |
Hellen CU, Pestova TV, Litterst M, Wimmer E. The cellular polypeptide p57 (pyrimidine tract-binding protein) binds to multiple sites in the poliovirus 5' nontranslated region. Journal of Virology. 68: 941-50. PMID 8289396 DOI: 10.1128/Jvi.68.2.941-950.1994 |
0.358 |
|
| 1994 |
Lama J, Paul AV, Harris KS, Wimmer E. Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as co-factor for RNA polymerase 3Dpol. The Journal of Biological Chemistry. 269: 66-70. PMID 8276867 |
0.302 |
|
| 1994 |
Bibb JA, Witherell G, Bernhardt G, Wimmer E. Interaction of poliovirus with its cell surface binding site. Virology. 201: 107-15. PMID 8178474 DOI: 10.1006/Viro.1994.1270 |
0.581 |
|
| 1994 |
Paul AV, Molla A, Wimmer E. Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C. Virology. 199: 188-99. PMID 8116242 DOI: 10.1006/Viro.1994.1111 |
0.415 |
|
| 1994 |
Mirzayan C, Wimmer E. Biochemical studies on poliovirus polypeptide 2C: evidence for ATPase activity. Virology. 199: 176-87. PMID 8116241 DOI: 10.1006/Viro.1994.1110 |
0.421 |
|
| 1994 |
Bernhardt G, Bibb JA, Bradley J, Wimmer E. Molecular characterization of the cellular receptor for poliovirus. Virology. 199: 105-13. PMID 8116232 DOI: 10.1006/Viro.1994.1102 |
0.638 |
|
| 1994 |
Hellen CU, Pestova TV, Wimmer E. Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis. Journal of Virology. 68: 6312-22. PMID 8083971 DOI: 10.1128/Jvi.68.10.6312-6322.1994 |
0.398 |
|
| 1994 |
Bibb JA, Bernhardt G, Wimmer E. The human poliovirus receptor alpha is a serine phosphoprotein. Journal of Virology. 68: 6111-5. PMID 8057492 DOI: 10.1128/Jvi.68.9.6111-6115.1994 |
0.569 |
|
| 1994 |
Bibb JA, Bernhardt G, Wimmer E. Cleavage site of the poliovirus receptor signal sequence. The Journal of General Virology. 75: 1875-81. PMID 8046389 DOI: 10.1099/0022-1317-75-8-1875 |
0.548 |
|
| 1994 |
Schmid M, Wimmer E. IRES-controlled protein synthesis and genome replication of poliovirus. Archives of Virology. Supplementum. 9: 279-89. PMID 8032259 |
0.395 |
|
| 1994 |
Pestova TV, Hellen CU, Wimmer E. A conserved AUG triplet in the 5' nontranslated region of poliovirus can function as an initiation codon in vitro and in vivo. Virology. 204: 729-37. PMID 7941341 DOI: 10.1006/Viro.1994.1588 |
0.398 |
|
| 1994 |
Lu HH, Yang CF, Murdin AD, Klein MH, Harber JJ, Kew OM, Wimmer E. Mouse neurovirulence determinants of poliovirus type 1 strain LS-a map to the coding regions of capsid protein VP1 and proteinase 2Apro. Journal of Virology. 68: 7507-15. PMID 7933134 DOI: 10.1128/Jvi.68.11.7507-7515.1994 |
0.433 |
|
| 1994 |
Harris KS, Xiang W, Alexander L, Lane WS, Paul AV, Wimmer E. Interaction of poliovirus polypeptide 3CDpro with the 5' and 3' termini of the poliovirus genome. Identification of viral and cellular cofactors needed for efficient binding. The Journal of Biological Chemistry. 269: 27004-14. PMID 7929441 |
0.319 |
|
| 1994 |
Bernhardt G, Harber J, Zibert A, deCrombrugghe M, Wimmer E. The poliovirus receptor: identification of domains and amino acid residues critical for virus binding. Virology. 203: 344-56. PMID 7914388 DOI: 10.1006/Viro.1994.1493 |
0.371 |
|
| 1994 |
Alexander L, Lu HH, Wimmer E. Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 1406-10. PMID 7509072 DOI: 10.1073/Pnas.91.4.1406 |
0.458 |
|
| 1994 |
Wimmer E, Harber JJ, Bibb JA, Gromeier M, Lu H, Bernhardt G. 7 Poliovirus Receptors Cold Spring Harbor Monograph Archive. 28: 101-127. DOI: 10.1101/087969429.28.101 |
0.623 |
|
| 1993 |
Molla A, Paul AV, Schmid M, Jang SK, Wimmer E. Studies on dicistronic polioviruses implicate viral proteinase 2Apro in RNA replication. Virology. 196: 739-47. PMID 8396807 DOI: 10.1006/Viro.1993.1531 |
0.442 |
|
| 1993 |
Molla A, Paul AV, Wimmer E. Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system. Journal of Virology. 67: 5932-8. PMID 8396661 DOI: 10.1128/Jvi.67.10.5932-5938.1993 |
0.425 |
|
| 1993 |
Hellen CU, Witherell GW, Schmid M, Shin SH, Pestova TV, Gil A, Wimmer E. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 90: 7642-6. PMID 8395052 DOI: 10.1073/Pnas.90.16.7642 |
0.445 |
|
| 1993 |
Cao X, Kuhn RJ, Wimmer E. Replication of poliovirus RNA containing two VPg coding sequences leads to a specific deletion event. Journal of Virology. 67: 5572-8. PMID 8394461 DOI: 10.1128/Jvi.67.9.5572-5578.1993 |
0.471 |
|
| 1993 |
Witherell GW, Gil A, Wimmer E. Interaction of polypyrimidine tract binding protein with the encephalomyocarditis virus mRNA internal ribosomal entry site. Biochemistry. 32: 8268-75. PMID 8394133 DOI: 10.1021/Bi00083A030 |
0.368 |
|
| 1993 |
Freistadt MS, Fleit HB, Wimmer E. Poliovirus receptor on human blood cells: a possible extraneural site of poliovirus replication. Virology. 195: 798-803. PMID 8393247 DOI: 10.1006/Viro.1993.1433 |
0.307 |
|
| 1993 |
Molla A, Hellen CU, Wimmer E. Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteinases by elastase-specific inhibitors. Journal of Virology. 67: 4688-95. PMID 8392608 DOI: 10.1128/Jvi.67.8.4688-4695.1993 |
0.337 |
|
| 1993 |
Molla A, Paul AV, Wimmer E. In vitro synthesis of poliovirus. Developments in Biological Standardization. 78: 39-53. PMID 8388831 |
0.316 |
|
| 1993 |
Mason PW, Baxt B, Brown F, Harber J, Murdin A, Wimmer E. Antibody-complexed foot-and-mouth disease virus, but not poliovirus, can infect normally insusceptible cells via the Fc receptor. Virology. 192: 568-77. PMID 8380665 DOI: 10.1006/Viro.1993.1073 |
0.35 |
|
| 1993 |
Wimmer E, Hellen CU, Cao X. Genetics of poliovirus. Annual Review of Genetics. 27: 353-436. PMID 8122908 DOI: 10.1146/Annurev.Ge.27.120193.002033 |
0.396 |
|
| 1993 |
Wimmer E, Nomoto A. Molecular biology and cell-free synthesis of poliovirus. Biologicals : Journal of the International Association of Biological Standardization. 21: 349-56. PMID 8024750 DOI: 10.1006/Biol.1993.1095 |
0.469 |
|
| 1992 |
Hellen CU, Wimmer E. The role of proteolytic processing in the morphogenesis of virus particles. Experientia. 48: 201-15. PMID 1740191 |
0.304 |
|
| 1992 |
Hellen CU, Wimmer E. Viral proteases as targets for chemotherapeutic intervention. Current Opinion in Biotechnology. 3: 643-9. PMID 1369416 DOI: 10.1016/0958-1669(92)90010-G |
0.343 |
|
| 1992 |
Harris KS, Reddigari SR, Nicklin MJ, Hämmerle T, Wimmer E. Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase. Journal of Virology. 66: 7481-9. PMID 1331532 DOI: 10.1128/Jvi.66.12.7481-7489.1992 |
0.411 |
|
| 1992 |
Zibert A, Selinka HC, Elroy-Stein O, Wimmer E. The soluble form of two N-terminal domains of the poliovirus receptor is sufficient for blocking viral infection. Virus Research. 25: 51-61. PMID 1329376 DOI: 10.1016/0168-1702(92)90099-U |
0.378 |
|
| 1992 |
Hämmerle T, Molla A, Wimmer E. Mutational analysis of the proposed FG loop of poliovirus proteinase 3C identifies amino acids that are necessary for 3CD cleavage and might be determinants of a function distinct from proteolytic activity. Journal of Virology. 66: 6028-34. PMID 1326654 DOI: 10.1128/Jvi.66.10.6028-6034.1992 |
0.455 |
|
| 1992 |
Mirzayan C, Wimmer E. Genetic analysis of an NTP-binding motif in poliovirus polypeptide 2C. Virology. 189: 547-55. PMID 1322588 DOI: 10.1016/0042-6822(92)90578-D |
0.486 |
|
| 1992 |
Hellen CU, Lee CK, Wimmer E. Determinants of substrate recognition by poliovirus 2A proteinase. Journal of Virology. 66: 3330-8. PMID 1316450 DOI: 10.1128/Jvi.66.6.3330-3338.1992 |
0.313 |
|
| 1992 |
Molla A, Jang SK, Paul AV, Reuer Q, Wimmer E. Cardioviral internal ribosomal entry site is functional in a genetically engineered dicistronic poliovirus. Nature. 356: 255-7. PMID 1313153 DOI: 10.1038/356255A0 |
0.439 |
|
| 1992 |
Selinka HC, Zibert A, Wimmer E. A chimeric poliovirus/CD4 receptor confers susceptibility to poliovirus on mouse cells. Journal of Virology. 66: 2523-6. PMID 1312641 DOI: 10.1128/Jvi.66.4.2523-2526.1992 |
0.335 |
|
| 1992 |
Hellen CU, Wimmer E. Maturation of poliovirus capsid proteins. Virology. 187: 391-7. PMID 1312265 DOI: 10.1016/0042-6822(92)90440-Z |
0.373 |
|
| 1991 |
Mirzayan C, Ingraham R, Wimmer E. Specificity of the polioviral proteinase 3C towards genetically engineered cleavage sites in the viral capsid. The Journal of General Virology. 72: 1159-63. PMID 1851816 DOI: 10.1099/0022-1317-72-5-1159 |
0.357 |
|
| 1991 |
Zibert A, Selinka HC, Elroy-Stein O, Moss B, Wimmer E. Vaccinia virus-mediated expression and identification of the human poliovirus receptor. Virology. 182: 250-9. PMID 1850905 DOI: 10.1016/0042-6822(91)90668-2 |
0.396 |
|
| 1991 |
Harber JJ, Bradley J, Anderson CW, Wimmer E. Catalysis of poliovirus VP0 maturation cleavage is not mediated by serine 10 of VP2. Journal of Virology. 65: 326-34. PMID 1845893 DOI: 10.1128/Jvi.65.1.326-334.1991 |
0.358 |
|
| 1991 |
Murdin AD, Mirzayan C, Kameda A, Wimmer E. The effect of site and mode of expression of a heterologous antigenic determinant on the properties of poliovirus hybrids. Microbial Pathogenesis. 10: 27-37. PMID 1713280 DOI: 10.1016/0882-4010(91)90063-G |
0.309 |
|
| 1991 |
Selinka HC, Zibert A, Wimmer E. Poliovirus can enter and infect mammalian cells by way of an intercellular adhesion molecule 1 pathway. Proceedings of the National Academy of Sciences of the United States of America. 88: 3598-602. PMID 1673787 DOI: 10.1073/Pnas.88.9.3598 |
0.333 |
|
| 1991 |
Partin K, Wimmer E, Carter C. Mutational analysis of a native substrate of the HIV-1 proteinase. Advances in Experimental Medicine and Biology. 306: 503-6. PMID 1667451 DOI: 10.1007/978-1-4684-6012-4_65 |
0.344 |
|
| 1991 |
Molla A, Paul AV, Wimmer E. Cell-free, de novo synthesis of poliovirus. Science (New York, N.Y.). 254: 1647-51. PMID 1661029 DOI: 10.1126/Science.1661029 |
0.438 |
|
| 1991 |
Pestova TV, Hellen CU, Wimmer E. Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein. Journal of Virology. 65: 6194-204. PMID 1656091 DOI: 10.1128/Jvi.65.11.6194-6204.1991 |
0.413 |
|
| 1991 |
Murdin AD, Kameda A, Murray MG, Wimmer E. Phenotypic characterization of antigenic hybrids of poliovirus. Microbial Pathogenesis. 10: 39-45. PMID 1649944 DOI: 10.1016/0882-4010(91)90064-H |
0.32 |
|
| 1991 |
Hellen CU, Fäcke M, Kräusslich HG, Lee CK, Wimmer E. Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220. Journal of Virology. 65: 4226-31. PMID 1649327 DOI: 10.1128/Jvi.65.8.4226-4231.1991 |
0.358 |
|
| 1991 |
Partin K, Zybarth G, Ehrlich L, DeCrombrugghe M, Wimmer E, Carter C. Deletion of sequences upstream of the proteinase improves the proteolytic processing of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 88: 4776-80. PMID 1647017 DOI: 10.1073/Pnas.88.11.4776 |
0.402 |
|
| 1990 |
Partin K, Kräusslich HG, Ehrlich L, Wimmer E, Carter C. Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase. Journal of Virology. 64: 3938-47. PMID 2196384 DOI: 10.1128/Jvi.64.8.3938-3947.1990 |
0.394 |
|
| 1990 |
Jang SK, Wimmer E. Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes & Development. 4: 1560-72. PMID 2174810 DOI: 10.1101/Gad.4.9.1560 |
0.423 |
|
| 1990 |
Reuer Q, Kuhn RJ, Wimmer E. Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg. Journal of Virology. 64: 2967-75. PMID 2159557 DOI: 10.1128/Jvi.64.6.2967-2975.1990 |
0.45 |
|
| 1990 |
Kräusslich HG, Hölscher C, Reuer Q, Harber J, Wimmer E. Myristoylation of the poliovirus polyprotein is required for proteolytic processing of the capsid and for viral infectivity. Journal of Virology. 64: 2433-6. PMID 2157900 DOI: 10.1128/Jvi.64.5.2433-2436.1990 |
0.449 |
|
| 1990 |
Roivainen M, Montagnon B, Chalumeau H, Murray M, Wimmer E, Hovi T. Improved distribution of antigenic site specificity of poliovirus-neutralizing antibodies induced by a protease-cleaved immunogen in mice. Journal of Virology. 64: 559-62. PMID 1688625 DOI: 10.1128/Jvi.64.2.559-562.1990 |
0.365 |
|
| 1990 |
EHRLICH LS, KRAÜSSLICH H, WIMMER E, CARTER CA. Expression in E. coli and Purification of Human Immunodeficiency Virus Type 1 Major Core Protein, p24 Annals of the New York Academy of Sciences. 616: 514-516. DOI: 10.1111/J.1749-6632.1990.Tb17879.X |
0.355 |
|
| 1989 |
Hellen CU, Kräusslich HG, Wimmer E. Proteolytic processing of polyproteins in the replication of RNA viruses. Biochemistry. 28: 9881-90. PMID 2695162 DOI: 10.1021/Bi00452A001 |
0.628 |
|
| 1989 |
Kräusslich HG, Ingraham RH, Skoog MT, Wimmer E, Pallai PV, Carter CA. Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides. Proceedings of the National Academy of Sciences of the United States of America. 86: 807-11. PMID 2644644 DOI: 10.1073/Pnas.86.3.807 |
0.334 |
|
| 1989 |
Jang SK, Davies MV, Kaufman RJ, Wimmer E. Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo. Journal of Virology. 63: 1651-60. PMID 2538648 DOI: 10.1128/Jvi.63.4.1651-1660.1989 |
0.383 |
|
| 1989 |
Mendelsohn CL, Wimmer E, Racaniello VR. Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell. 56: 855-65. PMID 2538245 DOI: 10.1016/0092-8674(89)90690-9 |
0.38 |
|
| 1988 |
Kräusslich HG, Schneider H, Zybarth G, Carter CA, Wimmer E. Processing of in vitro-synthesized gag precursor proteins of human immunodeficiency virus (HIV) type 1 by HIV proteinase generated in Escherichia coli. Journal of Virology. 62: 4393-7. PMID 3050149 DOI: 10.1128/Jvi.62.11.4393-4397.1988 |
0.318 |
|
| 1988 |
Nicklin MJ, Harris KS, Pallai PV, Wimmer E. Poliovirus proteinase 3C: large-scale expression, purification, and specific cleavage activity on natural and synthetic substrates in vitro. Journal of Virology. 62: 4586-93. PMID 2846872 DOI: 10.1128/Jvi.62.12.4586-4593.1988 |
0.323 |
|
| 1988 |
Kuhn RJ, Tada H, Ypma-Wong MF, Semler BL, Wimmer E. Mutational analysis of the genome-linked protein VPg of poliovirus. Journal of Virology. 62: 4207-15. PMID 2845132 DOI: 10.1128/Jvi.62.11.4207-4215.1988 |
0.39 |
|
| 1988 |
Paul AV, Yang CF, Jang SK, Kuhn RJ, Tada H, Nicklin M, Kräusslich HG, Lee CK, Wimmer E. Molecular events leading to poliovirus genome replication. Cold Spring Harbor Symposia On Quantitative Biology. 52: 343-52. PMID 2841067 DOI: 10.1101/Sqb.1987.052.01.039 |
0.303 |
|
| 1988 |
Kräusslich H, Nicklin MJH, Lee C, Wimmer E. Polyprotein processing in picornavirus replication Biochimie. 70: 119-130. PMID 2840974 DOI: 10.1016/0300-9084(88)90166-6 |
0.638 |
|
| 1988 |
Jang SK, Kräusslich HG, Nicklin MJ, Duke GM, Palmenberg AC, Wimmer E. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. Journal of Virology. 62: 2636-43. PMID 2839690 DOI: 10.1128/Jvi.62.8.2636-2643.1988 |
0.421 |
|
| 1988 |
Murray MG, Bradley J, Yang XF, Wimmer E, Moss EG, Racaniello VR. Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I. Science (New York, N.Y.). 241: 213-5. PMID 2838906 DOI: 10.1126/Science.2838906 |
0.365 |
|
| 1988 |
Murray MG, Kuhn RJ, Arita M, Kawamura N, Nomoto A, Wimmer E. Poliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys. Proceedings of the National Academy of Sciences of the United States of America. 85: 3203-7. PMID 2834736 DOI: 10.1073/Pnas.85.9.3203 |
0.328 |
|
| 1988 |
Kean KM, Agut H, Fichot O, Wimmer E, Girard M. A poliovirus mutant defective for self-cleavage at the COOH-terminus of the 3C protease exhibits secondary processing defects. Virology. 163: 330-40. PMID 2833011 DOI: 10.1016/0042-6822(88)90273-5 |
0.424 |
|
| 1988 |
Kuhn RJ, Tada H, Ypma-Wong MF, Dunn JJ, Semler BL, Wimmer E. Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants Proceedings of the National Academy of Sciences of the United States of America. 85: 519-523. PMID 2829191 DOI: 10.1073/Pnas.85.2.519 |
0.448 |
|
| 1987 |
Arnold E, Luo M, Vriend G, Rossmann MG, Palmenberg AC, Parks GD, Nicklin MJ, Wimmer E. Implications of the picornavirus capsid structure for polyprotein processing Proceedings of the National Academy of Sciences of the United States of America. 84: 21-25. PMID 3467351 DOI: 10.1073/Pnas.84.1.21 |
0.417 |
|
| 1987 |
Toyoda H, Yang CF, Takeda N, Nomoto A, Wimmer E. Analysis of RNA synthesis of type 1 poliovirus by using an in vitro molecular genetic approach. Journal of Virology. 61: 2816-2822. PMID 3039171 DOI: 10.1128/Jvi.61.9.2816-2822.1987 |
0.427 |
|
| 1987 |
Kräusslich HG, Nicklin MJ, Toyoda H, Etchison D, Wimmer E. Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. Journal of Virology. 61: 2711-2718. PMID 3039165 DOI: 10.1128/Jvi.61.9.2711-2718.1987 |
0.347 |
|
| 1987 |
Nicklin MJH, Krausslich HG, Toyoda H, Dunn JJ, Wimmer E. Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinases. Proceedings of the National Academy of Sciences of the United States of America. 84: 4002-4006. PMID 3035560 DOI: 10.1073/Pnas.84.12.4002 |
0.335 |
|
| 1987 |
Kuhn RJ, Wimmer E, Semler BL. Expression of the poliovirus genome from infectious cDNA is dependent upon arrangements of eukaryotic and prokaryotic sequences in recombinant plasmids Virology. 157: 560-564. PMID 3029989 DOI: 10.1016/0042-6822(87)90302-3 |
0.417 |
|
| 1987 |
Pincus SE, Rohl H, Wimmer E. Guanidine-dependent mutants of poliovirus: identification of three classes with different growth requirements Virology. 157: 83-88. PMID 3029969 DOI: 10.1016/0042-6822(87)90316-3 |
0.301 |
|
| 1987 |
Takeda N, Chen-Fu Y, Kuhn RJ, Wimmer E. Uridylylation of the genome-linked protein of poliovirus in vitro is dependent upon an endogenous RNA template. Virus Research. 8: 193-204. PMID 2825442 DOI: 10.1016/0168-1702(87)90015-3 |
0.394 |
|
| 1987 |
Paul AV, Schultz A, Pincus SE, Oroszlan S, Wimmer E. Capsid protein VP4 of poliovirus is N-myristoylated. Proceedings of the National Academy of Sciences of the United States of America. 84: 7827-7831. PMID 2825164 DOI: 10.1073/Pnas.84.22.7827 |
0.313 |
|
| 1987 |
Paul AV, Tada H, Helm Kvd, Wissel T, Kiehn R, Wimmer E, Deinhardt F. The entire nucleotide sequence of the genome of human hepatitis A virus (isolate MBB). Virus Research. 8: 153-171. PMID 2823500 DOI: 10.1016/0168-1702(87)90026-8 |
0.411 |
|
| 1986 |
Pincus SE, Wimmer E. Production of guanidine-resistant and -dependent poliovirus mutants from cloned cDNA: mutations in polypeptide 2C are directly responsible for altered guanidine sensitivity. Journal of Virology. 60: 793-796. PMID 3022012 DOI: 10.1128/Jvi.60.2.793-796.1986 |
0.31 |
|
| 1986 |
Mendelsohn C, Johnson B, Lionetti KA, Nobis P, Wimmer E, Racaniello VR. Transformation of a human poliovirus receptor gene into mouse cells Proceedings of the National Academy of Sciences of the United States of America. 83: 7845-7849. PMID 3020560 DOI: 10.1073/Pnas.83.20.7845 |
0.333 |
|
| 1986 |
Takeda N, Kuhn RJ, Yang CF, Takegami T, Wimmer E. Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells. Journal of Virology. 60: 43-53. PMID 3018300 DOI: 10.1128/Jvi.60.1.43-53.1986 |
0.408 |
|
| 1986 |
Toyoda H, Nicklin MJ, Murray MG, Anderson CW, Dunn JJ, Studier FW, Wimmer E. A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein. Cell. 45: 761-70. PMID 3011278 DOI: 10.1016/0092-8674(86)90790-7 |
0.366 |
|
| 1986 |
van der Werf S, Bradley J, Wimmer E, Studier FW, Dunn JJ. Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 83: 2330-4. PMID 3010307 DOI: 10.1073/Pnas.83.8.2330 |
0.405 |
|
| 1986 |
Omata T, Kohara M, Kuge S, Komatsu T, Abe S, Semler BL, Kameda A, Itoh H, Arita M, Wimmer E. Genetic analysis of the attenuation phenotype of poliovirus type 1 Journal of Virology. 58: 348-358. PMID 3009852 DOI: 10.1128/Jvi.58.2.348-358.1986 |
0.395 |
|
| 1986 |
Lloyd RE, Toyoda H, Etchison D, Wimmer E, Ehrenfeld E. Cleavage of the cap binding protein complex polypeptide p220 is not effected by the second poliovirus protease 2A. Virology. 150: 299-303. PMID 3006342 DOI: 10.1016/0042-6822(86)90291-6 |
0.366 |
|
| 1986 |
Pincus SE, Diamond DC, Emini EA, Wimmer E. Guanidine-selected mutants of poliovirus: mapping of point mutations to polypeptide 2C. Journal of Virology. 57: 638-646. PMID 3003395 DOI: 10.1128/Jvi.57.2.638-646.1986 |
0.392 |
|
| 1986 |
Diamond DC, Wimmer E, Helm Kvd, Deinhardt F. The genomic map of hepatitis A virus: an alternate analysis. Microbial Pathogenesis. 1: 217-219. PMID 2854598 DOI: 10.1016/0882-4010(86)90023-9 |
0.421 |
|
| 1986 |
Nicklin MJH, Toyoda H, Murray MG, Wimmer E. Proteolytic Processing in the Replication of Polio and Related Viruses Nature Biotechnology. 4: 33-42. DOI: 10.1038/Nbt0186-33 |
0.384 |
|
| 1985 |
Jameson BA, Bonin J, Wimmer E, Kew OM. Natural variants of the sabin type 1 vaccine strain of poliovirus and correlation with a poliovirus neutralization site Virology. 143: 337-341. PMID 2998009 DOI: 10.1016/0042-6822(85)90121-7 |
0.342 |
|
| 1985 |
Lee KAW, Edery I, Hanecak R, Wimmer E, Sonenberg N. Poliovirus protease 3C (P3-7c) does not cleave P220 of the eucaryotic mRNA cap-binding protein complex Journal of Virology. 55: 489-493. PMID 2991572 DOI: 10.1128/Jvi.55.2.489-493.1985 |
0.351 |
|
| 1985 |
Kohara M, Omata T, Kameda A, Semler BL, Itoh H, Wimmer E, Nomoto A. In vitro phenotypic markers of a poliovirus recombinant constructed from infectious cDNA clones of the neurovirulent Mahoney strain and the attenuated Sabin 1 strain Journal of Virology. 53: 786-792. PMID 2983090 DOI: 10.1128/Jvi.53.3.786-792.1985 |
0.405 |
|
| 1985 |
Emini EA, Schleif WA, Colonno RJ, Wimmer E. Antigenic conservation and divergence between the viral-specific proteins of poliovirus type 1 and various picornaviruses Virology. 140: 13-20. PMID 2981447 DOI: 10.1016/0042-6822(85)90441-6 |
0.381 |
|
| 1984 |
Argos P, Kamer G, Nicklin MJH, Wimmer E. Similarity in gene organization and homology between proteins of animal picomaviruses and a plant comovirus suggest common ancestry of these virus families Nucleic Acids Research. 12: 7251-7267. PMID 6384934 DOI: 10.1093/Nar/12.18.7251 |
0.43 |
|
| 1984 |
Hanecak R, Semler BL, Ariga H, Anderson CW, Wimmer E. Expression of a cloned gene segment of poliovirus in E. coli: Evidence for autocatalytic production of the viral proteinase Cell. 37: 1063-1073. PMID 6331675 DOI: 10.1016/0092-8674(84)90441-0 |
0.351 |
|
| 1984 |
Semler BL, Dorner AJ, Wimmer E. Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals Nucleic Acids Research. 12: 5123-5141. PMID 6330698 DOI: 10.1093/Nar/12.12.5123 |
0.423 |
|
| 1984 |
Takegami T, Kuhn RJ, Anderson CW, Wimmer E. Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 80: 7447-51. PMID 6324172 DOI: 10.1073/Pnas.80.24.7447 |
0.41 |
|
| 1984 |
Dorner AJ, Semler BL, Jackson RJ, Hanecak R, Duprey E, Wimmer E. In vitro translation of poliovirus RNA: Utilization of internal initiation sites in reticulocyte lysate Journal of Virology. 50: 507-514. PMID 6323749 DOI: 10.1128/Jvi.50.2.507-514.1984 |
0.42 |
|
| 1984 |
Emini EA, Jameson BA, Wimmer E. Identification of a new neutralization antigenic site on poliovirus coat protein VP2. Journal of Virology. 52: 719-21. PMID 6208380 DOI: 10.1128/Jvi.52.2.719-721.1984 |
0.333 |
|
| 1984 |
Emini EA, Leibowitz J, Diamond DC, Bonin J, Wimmer E. Recombinants of Mahoney and Sabin strain poliovirus type 1: Analysis of In vitro phenotypic markers and evidence that resistance to guanidine maps in the nonstructural proteins Virology. 137: 74-85. PMID 6089422 DOI: 10.1016/0042-6822(84)90010-2 |
0.407 |
|
| 1983 |
Takegami T, Semler BL, Anderson CW, Wimmer E. Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides Virology. 128: 33-47. PMID 6308897 DOI: 10.1016/0042-6822(83)90316-1 |
0.372 |
|
| 1983 |
Semler BL, Haneck R, Dorner LF, Anderson CW, Wimmer E. Poliovirus RNA synthesis in Vitro: Structuralelements and antibody inhibition Virology. 126: 624-635. PMID 6305005 DOI: 10.1016/S0042-6822(83)80018-X |
0.42 |
|
| 1983 |
Adler CJ, Elzinga M, Wimmer E. The genome-linked protein of picornaviruses. VIII. Complete amino acid sequence of poliovirus VPg and carboxy-terminal analysis of its precursor, P3-9 Journal of General Virology. 64: 349-355. PMID 6300288 DOI: 10.1099/0022-1317-64-2-349 |
0.403 |
|
| 1983 |
Emini EA, Kao SY, Lewis AJ, Crainic R, Wimmer E. Functional basis of poliovirus neutralization determined with monospecific neutralizing antibodies. Journal of Virology. 46: 466-474. PMID 6188863 DOI: 10.1128/Jvi.46.2.466-474.1983 |
0.317 |
|
| 1983 |
Emini EA, Dorner AJ, Dorner LF, Jameson BA, Wimmer E. Identification of a poliovirus neutralization epitope through use of neutralizing antiserum raised against a purified viral structural protein. Virology. 124: 144-51. PMID 6186073 DOI: 10.1016/0042-6822(83)90297-0 |
0.308 |
|
| 1983 |
Emini EA, Jameson BA, Lewis AJ, Larsen GR, Wimmer E. Poliovirus neutralization epitopes: analysis and localization with neutralizing monoclonal antibodies. Journal of Virology. 43: 997-1005. PMID 6183443 DOI: 10.1128/Jvi.43.3.997-1005.1982 |
0.352 |
|
| 1982 |
Wimmer E. Genome-linked proteins of viruses Cell. 28: 199-201. PMID 7060125 DOI: 10.1016/0092-8674(82)90335-X |
0.36 |
|
| 1982 |
Hanecak R, Semler BL, Anderson CW, Wimmer E. Proteolytic processing of poliovirus polypeptides: Antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs Proceedings of the National Academy of Sciences of the United States of America. 79: 3973-3977. PMID 6287457 DOI: 10.1073/Pnas.79.13.3973 |
0.311 |
|
| 1982 |
Emini EA, Elzinga M, Wimmer E. Carboxy-terminal analysis of poliovirus proteins: Termination of poliovirus RNA translation and location of unique poliovirus polyprotein cleavage sites Journal of Virology. 42: 194-199. PMID 6283138 DOI: 10.1128/Jvi.42.1.194-199.1982 |
0.407 |
|
| 1982 |
Larsen GR, Anderson CW, Dorner AJ, Semler BL, Wimmer E. Cleavage sites within the poliovirus capsid protein precursors Journal of Virology. 41: 340-344. PMID 6283126 DOI: 10.1128/Jvi.41.1.340-344.1982 |
0.383 |
|
| 1982 |
Semler BL, Anderson CW, Hanecak R, Dorner LF, Wimmer E. A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide Cell. 28: 405-412. PMID 6277514 DOI: 10.1016/0092-8674(82)90358-0 |
0.421 |
|
| 1982 |
Dorner AJ, Dorner LF, Larsen GR, Wimmer E, Anderson CW. Identification of the initiation site of poliovirus polyprotein synthesis. Journal of Virology. 42: 1017-1028. DOI: 10.1128/Jvi.42.3.1017-1028.1982 |
0.398 |
|
| 1981 |
Rothberg PG, Wimmer E. Mononucleotide and dinucleotide frequencies, and codon usage in poliovirion RNA. Nucleic Acids Research. 9: 6221-6230. PMID 6275352 DOI: 10.1093/Nar/9.23.6221 |
0.367 |
|
| 1981 |
Werf Svd, Bregegere F, Kopecka H, Kitamura N, Rothberg PG, Kourilsky P, Wimmer E, Girard M. Molecular cloning of the genome of poliovirus type 1. Proceedings of the National Academy of Sciences of the United States of America. 78: 5983-5987. PMID 6273836 DOI: 10.1073/Pnas.78.10.5983 |
0.411 |
|
| 1981 |
Dorner AJ, Rothberg PG, Wimmer E. The fate of VPg during in vitro translation of poliovirus RNA Febs Letters. 132: 219-223. PMID 6271591 DOI: 10.1016/0014-5793(81)81164-7 |
0.431 |
|
| 1981 |
Semler BL, Hanecak R, Anderson CW, Wimmer E. Cleavage sites in the polypeptide precursors of poliovirus protein P2-X Virology. 114: 589-594. PMID 6270891 DOI: 10.1016/0042-6822(81)90242-7 |
0.324 |
|
| 1981 |
Semler BL, Anderson CW, Kitamura N, Rothberg PG, Wishart WL, Wimmer E. Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing Proceedings of the National Academy of Sciences of the United States of America. 78: 3464-3468. PMID 6267593 DOI: 10.1073/Pnas.78.6.3464 |
0.382 |
|
| 1981 |
Nomoto A, Kitamura N, Lee JJ, Rothberg PG, Imura N, Wimmer E. Identification of point mutations in the genome of the poliovirus Sabin vaccine LSc 2ab, and catalogue of RNase T1- and RNase A-resistant oligonucleotides of poliovirus type 1 (Mahoney) RNA. Virology. 112: 217-227. PMID 6264681 DOI: 10.1016/0042-6822(81)90627-9 |
0.353 |
|
| 1981 |
Kitamura N, Semler BL, Rothberg PG, Larsen GR, Adler CJ, Dorner AJ, Emini EA, Hanecak R, Lee JJ, Van Der Werf S, Anderson CW, Wimmer E. Primary structure, gene organization and polypeptide expression of poliovirus RNA Nature. 291: 547-553. PMID 6264310 DOI: 10.1038/291547A0 |
0.427 |
|
| 1981 |
Larsen GR, Semler BL, Wimmer E. Stable hairpin structure within the 5'-terminal 85 nucleotides of poliovirus RNA Journal of Virology. 37: 328-335. PMID 6260985 DOI: 10.1128/Jvi.37.1.328-335.1981 |
0.402 |
|
| 1981 |
Pallansch MA, Kew OM, Palmenberg AC, Golini F, Wimmer E, Rueckert RR. Picornaviral VPg sequences are contained in the replicase precursor. Journal of Virology. 35: 414-9. PMID 6255181 DOI: 10.1128/Jvi.35.2.414-419.1980 |
0.411 |
|
| 1980 |
Larsen GR, Domer AJ, Harris TJR, Wimmer E. The structure of poliovirus replicative form Nucleic Acids Research. 8: 1217-1230. PMID 6253931 DOI: 10.1093/Nar/8.6.1217 |
0.384 |
|
| 1980 |
Golini F, Semler BL, Dorner AJ, Wimmer E. Protein-linked RNA of poliovirus is competent to form an initiation complex of translation in vitro Nature. 287: 600-603. PMID 6253803 DOI: 10.1038/287600A0 |
0.392 |
|
| 1980 |
Kitamura N, Adler CJ, Rothberg PG, Martinko J, Nathenson SG, Wimmer E. The genome-linked protein of picornaviruses. VII. Genetic mapping of poliovirus VPg by protein and RNA sequence studies. Cell. 21: 295-302. PMID 6250717 DOI: 10.1016/0092-8674(80)90137-3 |
0.437 |
|
| 1980 |
Babich A, Wimmer E, Toyoda H, Nomoto A. The Genome-Linked Protein of Picornaviruses: VI. the 5'-terminal protein of poliovirus type 2 RNA is covalently linked to a nonanucleotide identical to that of poliovirus type 1 RNA Intervirology. 13: 192-199. PMID 6246035 DOI: 10.1159/000149125 |
0.414 |
|
| 1980 |
Kitamura N, Wimmer E. Sequence of 1060 3'-terminal nucleotides of poliovirus RNA as determined by a modification of the dideoxynucleotide method. Proceedings of the National Academy of Sciences of the United States of America. 77: 3196-3200. PMID 6158042 DOI: 10.1073/Pnas.77.6.3196 |
0.375 |
|
| 1979 |
Lee YF, Kitamura N, Nomoto A, Wimmer E. Sequence Studies of Poliovirus RNA. IV. Nucleotide Sequence Complexities of Poliovirus Type 1, Type 2 and Two Type 1 Defective Interfering Particles RNAs, and Fingerprint of the Poliovirus Type 3 Genome Journal of General Virology. 44: 311-322. PMID 230285 DOI: 10.1099/0022-1317-44-2-311 |
0.353 |
|
| 1979 |
Nomoto A, Jacobson A, Lee YF, Dunn J, Wimmer E. Defective interfering particles of poliovirus: mapping of the deletion and evidence that the deletions in the genomes of DI(1), (2) and (3) are located in the same region. Journal of Molecular Biology. 128: 179-196. PMID 219204 DOI: 10.1016/0022-2836(79)90125-6 |
0.445 |
|
| 1979 |
Nomoto A, Lee YF, Babich A, Jacobson A, Dunn JJ, Wimmer E. Restricted fragmentation of poliovirus type 1, 2 and 3 RNAs by ribonuclease III. Journal of Molecular Biology. 128: 165-177. PMID 219203 DOI: 10.1016/0022-2836(79)90124-4 |
0.388 |
|
| 1979 |
Wu M, Davidson N, Wimmer E. An electron microscope study of the proteins attached to polio virus RNA and its replicative form (RF). Nucleic Acids Research. 5: 4711-23. PMID 218168 DOI: 10.1093/Nar/5.12.4711 |
0.406 |
|
| 1978 |
Rothberg PG, Harris TJR, Nomoto A, Wimmer E. O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus Proceedings of the National Academy of Sciences of the United States of America. 75: 4868-4872. PMID 217003 DOI: 10.1073/Pnas.75.10.4868 |
0.346 |
|
| 1978 |
Harris TJR, Dunn JJ, Wimmer E. Identification of specific fragments containing the 5′ end of poliovirus RNA after ribonuclease III digestion Nucleic Acids Research. 5: 4039-4054. PMID 214765 DOI: 10.1093/Nar/5.11.4039 |
0.386 |
|
| 1978 |
Deng C, Wimmer E. Two different murine sarcoma virus isolates have homologous genome sequences: implication for their origin. Virology. 89: 309-313. PMID 210574 DOI: 10.1016/0042-6822(78)90063-6 |
0.394 |
|
| 1978 |
Golini F, Nomoto A, Wimmer E. The genome-linked protein of picornaviruses. IV. Difference in the VPg's of encephalomyocarditis virus and poliovirus as evidence that the genome-linked proteins are virus-coded. Virology. 89: 112-118. PMID 210567 DOI: 10.1016/0042-6822(78)90045-4 |
0.439 |
|
| 1977 |
Nomoto A, Kitamura N, Golini F, Wimmer E. The 5'-terminal structures of poliovirion RNA and poliovirus mRNA differ only in the genome-linked protein VPg. Proceedings of the National Academy of Sciences of the United States of America. 74: 5345-5349. PMID 202952 DOI: 10.1073/Pnas.74.12.5345 |
0.444 |
|
| 1977 |
Nomoto A, Detjen B, Pozzatti R, Wimmer E. The location of the polio genome protein in viral RNAs and its implication for RNA synthesis. Nature. 268: 208-213. PMID 196204 DOI: 10.1038/268208A0 |
0.428 |
|
| 1977 |
Lee YF, Nomoto A, Wimmer E. The genome of poliovirus is an exceptional eukaryotic mRNA. Progress in Nucleic Acid Research and Molecular Biology. 19: 89-96. PMID 190646 DOI: 10.1016/S0079-6603(08)60910-1 |
0.39 |
|
| 1977 |
Lee YF, Nomoto A, Detjen BM, Wimmer E. A protein covalently linked to poliovirus genome RNA. Proceedings of the National Academy of Sciences of the United States of America. 74: 59-63. PMID 189316 DOI: 10.1073/Pnas.74.1.59 |
0.413 |
|
| 1976 |
Lee YF, Wimmer E. “Fingerprinting” high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA Nucleic Acids Research. 3: 1647-1658. PMID 184435 DOI: 10.1093/Nar/3.7.1647 |
0.35 |
|
| 1976 |
Nomoto A, Lee YF, Wimmer E. The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np Proceedings of the National Academy of Sciences of the United States of America. 73: 375-380. PMID 174106 DOI: 10.1073/Pnas.73.2.375 |
0.355 |
|
| 1975 |
Tal J, Jacobi P, Raskas HJ, Wimmer E. Fingerprint analyses of cytoplasmic adenovirus 2 RNA size classes synthesized late in productive infection. Virology. 68: 547-549. PMID 1198928 DOI: 10.1016/0042-6822(75)90296-2 |
0.316 |
|
| 1972 |
Yogo Y, Wimmer E. Polyadenylic Acid at the 3′-Terminus of Poliovirus RNA Proceedings of the National Academy of Sciences of the United States of America. 69: 1877-1882. PMID 4340162 DOI: 10.1073/Pnas.69.7.1877 |
0.383 |
|
| 1971 |
Cole CN, Smoler D, Wimmer E, Baltimore D. Defective interfering particles of poliovirus. I. Isolation and physical properties. Journal of Virology. 7: 478-85. PMID 4329564 DOI: 10.1128/Jvi.7.4.478-485.1971 |
0.388 |
|
| 1965 |
Brockmann H, Wimmer E. [Rhodomycin, 8. Antibiotics from Actinomycetes, LI. Structure of beta-, gamma-, epsilon- and zeta-rhodomycinone]. Chemische Berichte. 98: 2797-804. PMID 5860385 DOI: 10.1002/Cber.19650980904 |
0.349 |
|
| 1963 |
Brockmann H, Wimmer E. Synthese von Descarbomethoxy-η-iso-pyrromycinon und anderen Hydroxy-tetracenchinonen Chemische Berichte. 96: 2399-2409. DOI: 10.1002/Cber.19630960918 |
0.358 |
|
| 1961 |
Brockmann H, Wimmer E. Synthese des Descarbomethoxy-?-iso-pyrromycinons Die Naturwissenschaften. 48: 162-162. DOI: 10.1007/Bf00639544 |
0.36 |
|
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