Anjali Rajadhyaksha - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Ca2+, dopamine, drug abuse
Website:
http://www.med.cornell.edu/research/arajadhyaksha/

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hackett J, Nadkarni V, Singh RS, Carthy CL, Antigua S, Hall BS, Rajadhyaksha AM. Repeat investigation during social preference behavior is suppressed in male mice with prefrontal cortex (Ca 1.2)-deficiency through the dysregulation of neural dynamics. Biorxiv : the Preprint Server For Biology. PMID 37425963 DOI: 10.1101/2023.06.24.546368  0.755
2023 Fetcho RN, Hall BS, Estrin DJ, Walsh AP, Schuette PJ, Kaminsky J, Singh A, Roshgodal J, Bavley CC, Nadkarni V, Antigua S, Huynh TN, Grosenick L, Carthy C, Komer L, ... ... Rajadhyaksha AM, et al. Regulation of social interaction in mice by a frontostriatal circuit modulated by established hierarchical relationships. Nature Communications. 14: 2487. PMID 37120443 DOI: 10.1038/s41467-023-37460-6  0.751
2023 Baker MR, Lee AS, Rajadhyaksha AM. L-type calcium channels and neuropsychiatric diseases: Insights into genetic risk variant-associated genomic regulation and impact on brain development. Channels (Austin, Tex.). 17: 2176984. PMID 36803254 DOI: 10.1080/19336950.2023.2176984  0.392
2022 Martínez-Rivera A, Hao J, Rice R, Inturrisi CE, Rajadhyaksha AM. Ca1.3 L-type Ca channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference. Neuropharmacology. 224: 109368. PMID 36481277 DOI: 10.1016/j.neuropharm.2022.109368  0.442
2020 Bavley CC, Fetcho RN, Burgdorf CE, Walsh AP, Fischer DK, Hall BS, Sayles NM, Contoreggi NH, Hackett JE, Antigua SA, Babij R, De Marco García NV, Kash TL, Milner TA, Liston C, ... Rajadhyaksha AM, et al. A dual-virus strategy for the deletion of cacan1c within the prelimbic to nucleus accumbens core projection. Molecular Psychiatry. 25: 2201-2202. PMID 32973243 DOI: 10.1038/s41380-020-00886-1  0.734
2020 Yang J, Ma Q, Dincheva I, Giza J, Jing D, Marinic T, Milner TA, Rajadhyaksha A, Lee FS, Hempstead BL. SorCS2 is required for social memory and trafficking of the NMDA receptor. Molecular Psychiatry. PMID 31988435 DOI: 10.1038/S41380-020-0650-7  0.373
2020 Burgdorf CE, Bavley CC, Fischer DK, Walsh AP, Martinez-Rivera A, Hackett JE, Zallar LJ, Ireton KE, Hofmann F, Hell JW, Huganir RL, Rajadhyaksha AM. Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Ca1.2 channels in extinction of cocaine conditioned place preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31905369 DOI: 10.1038/s41386-019-0597-z  0.44
2019 Bavley CC, Fetcho RN, Burgdorf CE, Walsh AP, Fischer DK, Hall BS, Sayles NM, Contoreggi NH, Hackett JE, Antigua SA, Babij R, De Marco García NV, Kash TL, Milner TA, Liston C, ... Rajadhyaksha AM, et al. Correction: Cocaine- and stress-primed reinstatement of drug-associated memories elicit differential behavioral and frontostriatal circuit activity patterns via recruitment of L-type Ca channels. Molecular Psychiatry. PMID 31811261 DOI: 10.1038/s41380-019-0624-9  0.787
2019 Bavley CC, Fetcho RN, Burgdorf CE, Walsh AP, Fischer DK, Hall BS, Sayles NM, Contoreggi NH, Hackett JE, Antigua SA, Babij R, Kash TL, Milner TA, Liston C, Rajadhyaksha AM. Cocaine- and stress-primed reinstatement of drug-associated memories elicit differential behavioral and frontostriatal circuit activity patterns via recruitment of L-type Ca channels. Molecular Psychiatry. PMID 31501511 DOI: 10.1038/S41380-019-0513-2  0.8
2018 Addy NA, Nunes EJ, Hughley SM, Small KM, Baracz SJ, Haight JL, Rajadhyaksha AM. The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29773910 DOI: 10.1038/S41386-018-0080-2  0.353
2017 Burgdorf CE, Schierberl KC, Lee AS, Fischer DK, Van Kempen TA, Mudragel V, Huganir RL, Milner TA, Glass MJ, Rajadhyaksha AM. Extinction of contextual cocaine memories requires Cav1.2 within D1R-expressing cells and recruits hippocampal Cav1.2-dependent signaling mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29089442 DOI: 10.1523/Jneurosci.2397-17.2017  0.806
2017 Fischer DK, Rice RC, Martinez-Rivera A, Donohoe M, Rajadhyaksha AM. Altered reward sensitivity in female offspring of cocaine-exposed fathers. Behavioural Brain Research. PMID 28552600 DOI: 10.1016/j.bbr.2017.05.054  0.306
2017 Martínez-Rivera A, Hao J, Tropea TF, Giordano TP, Kosovsky M, Rice RC, Lee A, Huganir RL, Striessnig J, Addy NA, Han S, Rajadhyaksha AM. Enhancing VTA Cav1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. Molecular Psychiatry. PMID 28194001 DOI: 10.1038/mp.2017.9  0.421
2016 Kabir ZD, Lee AS, Burgdorf CE, Fischer D, Rajadhyaksha AM, Mok E, Rizzo B, Rice RC, Singh K, Ota KT, Gerhard DM, Schierberl KC, Glass M, Duman RS, Rajadhyaksha AM. Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27922594 DOI: 10.1038/Npp.2016.271  0.76
2016 Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI, Francesconi A, Edwards RH, Milner TA, Rajadhyaksha AM, van Roessel PJ, et al. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron. PMID 27263971 DOI: 10.1016/J.Neuron.2016.05.008  0.743
2016 Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA. The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons. Eneuro. 3. PMID 27066530 DOI: 10.1523/ENEURO.0006-16.2016  0.422
2016 Kabir ZD, Lee AS, Rajadhyaksha AM. L-type Ca(2+) channels in mood, cognition and addiction: Integrating human and rodent studies with a focus on behavioural endophenotypes. The Journal of Physiology. PMID 26913808 DOI: 10.1113/Jp270673  0.409
2014 Liu Y, Harding M, Pittman A, Dore J, Striessnig J, Rajadhyaksha A, Chen X. Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area. Journal of Neurophysiology. 112: 1119-30. PMID 24848473 DOI: 10.1152/Jn.00757.2013  0.382
2013 Schierberl KC, Rajadhyaksha AM. Stereotaxic microinjection of viral vectors expressing Cre recombinase to study the role of target genes in cocaine conditioned place preference. Journal of Visualized Experiments : Jove. PMID 23929203 DOI: 10.3791/50600  0.782
2013 Lau NM, Green PH, Taylor AK, Hellberg D, Ajamian M, Tan CZ, Kosofsky BE, Higgins JJ, Rajadhyaksha AM, Alaedini A. Markers of Celiac Disease and Gluten Sensitivity in Children with Autism. Plos One. 8: e66155. PMID 23823064 DOI: 10.1371/Journal.Pone.0066155  0.497
2013 Ajamian M, Kosofsky BE, Wormser GP, Rajadhyaksha AM, Alaedini A. Serologic markers of Lyme disease in children with autism. Jama. 309: 1771-3. PMID 23632714 DOI: 10.1001/Jama.2013.618  0.487
2012 Lee AS, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Selective genetic deletion of cacna1c in the mouse prefrontal cortex. Molecular Psychiatry. 17: 1051. PMID 23096954 DOI: 10.1038/Mp.2012.149  0.312
2012 Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Forebrain elimination of cacna1c mediates anxiety-like behavior in mice. Molecular Psychiatry. 17: 1054-5. PMID 22665262 DOI: 10.1038/Mp.2012.71  0.429
2012 Kabir ZD, Lourenco F, Byrne ME, Katzman A, Lee F, Rajadhyaksha AM, Kosofsky BE. Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype. Developmental Neuroscience. 34: 184-97. PMID 22572518 DOI: 10.1159/000337712  0.639
2012 Schierberl K, Giordano T, Satpute S, Hao J, Kaur G, Hofmann F, Moosmang S, Striessnig J, Rajadhyaksha A. Cav 1.3 L-type Ca ( 2+) channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure. Channels (Austin, Tex.). 6: 11-7. PMID 22419037 DOI: 10.4161/Chan.19324  0.811
2012 Rajadhyaksha AM, Ra S, Kishinevsky S, Lee AS, Romanienko P, DuBoff M, Yang C, Zupan B, Byrne M, Daruwalla ZR, Mark W, Kosofsky BE, Toth M, Higgins JJ. Behavioral characterization of cereblon forebrain-specific conditional null mice: a model for human non-syndromic intellectual disability. Behavioural Brain Research. 226: 428-34. PMID 21995942 DOI: 10.1016/J.Bbr.2011.09.039  0.651
2012 Schierberl K, Giordano T, Satpute S, Hao J, Kaur G, Hofmann F, Moosmang S, Striessnig J, Rajadhyaksha A. Cav1.3 L-type Ca2+ channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure Channels. 6. DOI: 10.4161/chan.6.1.19324  0.799
2011 Tropea TF, Kabir ZD, Kaur G, Rajadhyaksha AM, Kosofsky BE. Enhanced dopamine D1 and BDNF signaling in the adult dorsal striatum but not nucleus accumbens of prenatal cocaine treated mice. Frontiers in Psychiatry. 2: 67. PMID 22162970 DOI: 10.3389/Fpsyt.2011.00067  0.644
2011 Schierberl K, Hao J, Tropea TF, Ra S, Giordano TP, Xu Q, Garraway SM, Hofmann F, Moosmang S, Striessnig J, Inturrisi CE, Rajadhyaksha AM. Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13562-75. PMID 21940447 DOI: 10.1523/Jneurosci.2315-11.2011  0.812
2011 Ren JQ, Jiang Y, Wang Z, McCarthy D, Rajadhyaksha AM, Tropea TF, Kosofsky BE, Bhide PG. Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference. Neuropharmacology. 60: 295-302. PMID 20854831 DOI: 10.1016/J.Neuropharm.2010.09.012  0.63
2010 Giordano TP, Tropea TF, Satpute SS, Sinnegger-Brauns MJ, Striessnig J, Kosofsky BE, Rajadhyaksha AM. Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 17051-62. PMID 21159975 DOI: 10.1523/Jneurosci.2255-10.2010  0.664
2010 Rajadhyaksha AM, Elemento O, Puffenberger EG, Schierberl KC, Xiang JZ, Putorti ML, Berciano J, Poulin C, Brais B, Michaelides M, Weleber RG, Higgins JJ. Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa. American Journal of Human Genetics. 87: 643-54. PMID 21070897 DOI: 10.1016/J.Ajhg.2010.10.013  0.743
2010 Gregus AM, Tropea TF, Wang Y, Hauck SC, Costa AC, Rajadhyaksha AM, Inturrisi CE. Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference. Neuroscience Letters. 468: 186-9. PMID 19878705 DOI: 10.1016/J.Neulet.2009.10.071  0.329
2008 Tropea TF, Kosofsky BE, Rajadhyaksha AM. Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of Neurochemistry. 106: 1780-90. PMID 18554320 DOI: 10.1111/J.1471-4159.2008.05518.X  0.656
2008 Higgins JJ, Hao J, Kosofsky BE, Rajadhyaksha AM. Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation. Neurogenetics. 9: 219-23. PMID 18414909 DOI: 10.1007/S10048-008-0128-2  0.587
2008 Covington HE, Tropea TF, Rajadhyaksha AM, Kosofsky BE, Miczek KA. NMDA receptors in the rat VTA: a critical site for social stress to intensify cocaine taking. Psychopharmacology. 197: 203-16. PMID 18097654 DOI: 10.1007/S00213-007-1024-4  0.633
2006 Giordano TP, Satpute SS, Striessnig J, Kosofsky BE, Rajadhyaksha AM. Up-regulation of dopamine D(2)L mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Ca(v)1.3 L-type Ca(2+) channels. Journal of Neurochemistry. 99: 1197-206. PMID 17026527 DOI: 10.1111/J.1471-4159.2006.04186.X  0.621
2005 Rajadhyaksha AM, Kosofsky BE. Psychostimulants, Protein phosphorylation and Gene expression: a growing role of L-type calcium channels. Cellscience. 2: 127-144. PMID 16724157 DOI: 10.1901/jaba.2005.2-127  0.563
2005 Rajadhyaksha AM, Kosofsky BE. Psychostimulants, L-type calcium channels, kinases, and phosphatases. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 494-502. PMID 16151049 DOI: 10.1177/1073858405278236  0.619
2005 Guerriero RM, Rajadhyaksha A, Crozatier C, Giros B, Nosten-Bertrand M, Kosofsky BE. Augmented constitutive CREB expression in the nucleus accumbens and striatum may contribute to the altered behavioral response to cocaine of adult mice exposed to cocaine in utero. Developmental Neuroscience. 27: 235-48. PMID 16046859 DOI: 10.1159/000085997  0.676
2004 Eaton ME, Macías W, Youngs RM, Rajadhyaksha A, Dudman JT, Konradi C. L-type Ca2+ channel blockers promote Ca2+ accumulation when dopamine receptors are activated in striatal neurons. Brain Research. Molecular Brain Research. 131: 65-72. PMID 15530653 DOI: 10.1016/J.Molbrainres.2004.08.007  0.676
2004 Rajadhyaksha A, Husson I, Satpute SS, Küppenbender KD, Ren JQ, Guerriero RM, Standaert DG, Kosofsky BE. L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7464-76. PMID 15329393 DOI: 10.1523/Jneurosci.0612-04.2004  0.658
2003 Dudman JT, Eaton ME, Rajadhyaksha A, Macías W, Taher M, Barczak A, Kameyama K, Huganir R, Konradi C. Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1. Journal of Neurochemistry. 87: 922-34. PMID 14622123 DOI: 10.1046/J.1471-4159.2003.02067.X  0.661
2001 Macías W, Carlson R, Rajadhyaksha A, Barczak A, Konradi C. Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Research. 890: 222-32. PMID 11164788 DOI: 10.1016/S0006-8993(00)03163-2  0.645
2000 Leveque JC, Macías W, Rajadhyaksha A, Carlson RR, Barczak A, Kang S, Li XM, Coyle JT, Huganir RL, Heckers S, Konradi C. Intracellular modulation of NMDA receptor function by antipsychotic drugs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4011-20. PMID 10818136 DOI: 10.1523/Jneurosci.20-11-04011.2000  0.602
1999 Rajadhyaksha A, Barczak A, Macías W, Leveque JC, Lewis SE, Konradi C. L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6348-59. PMID 10414964 DOI: 10.1523/Jneurosci.19-15-06348.1999  0.654
1998 Rajadhyaksha A, Leveque J, Macías W, Barczak A, Konradi C. Molecular components of striatal plasticity: the various routes of cyclic AMP pathways. Developmental Neuroscience. 20: 204-15. PMID 9691194 DOI: 10.1159/000017314  0.636
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