Jeffrey W. Roberts - Publications

Affiliations: 
Molecular and Cell Biology Cornell University, Ithaca, NY, United States 
Area:
DNA transcription by the enzyme RNA polymerase
Website:
https://mbg.cornell.edu/people/emeriti-faculty/

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Roberts J. A Tale of Good Fortune in the Era of DNA. Annual Review of Microbiology. PMID 32453973 DOI: 10.1146/Annurev-Micro-012520-073029  0.454
2019 Roberts JW. Mechanisms of Bacterial Transcription Termination. Journal of Molecular Biology. PMID 30978344 DOI: 10.1016/J.Jmb.2019.04.003  0.553
2019 Ma J, Tan C, Gao X, Fulbright RM, Roberts JW, Wang MD. Transcription factor regulation of RNA polymerase's torque generation capacity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30635423 DOI: 10.1016/J.Bpj.2018.11.1161  0.539
2019 Ma J, Tan C, Gao X, Fulbright RM, Roberts JW, Wang MD. Transcription Factor Regulation of RNA Polymerase's Torque Generation Capacity Biophysical Journal. 116: 210a. DOI: 10.1016/j.bpj.2018.11.1161  0.423
2018 Le TT, Yang Y, Tan C, Suhanovsky M, Fulbright RM, Inman JT, Li M, Lee J, Roberts JW, Deaconescu AM, Wang MD. MFD Dynamically Regulates Transcription Biophysical Journal. 114: 247a. DOI: 10.1016/J.Bpj.2017.11.1377  0.379
2017 Le TT, Yang Y, Tan C, Suhanovsky MM, Fulbright RM, Inman JT, Li M, Lee J, Perelman S, Roberts JW, Deaconescu AM, Wang MD. Mfd Dynamically Regulates Transcription via a Release and Catch-Up Mechanism. Cell. PMID 29224782 DOI: 10.1016/J.Cell.2017.11.017  0.512
2016 Bird JG, Strobel EJ, Roberts JW. A universal transcription pause sequence is an element of initiation factor σ70-dependent pausing. Nucleic Acids Research. PMID 27098041 DOI: 10.1093/Nar/Gkw285  0.794
2015 Strobel EJ, Roberts JW. Two transcription pause elements underlie a σ70-dependent pause cycle. Proceedings of the National Academy of Sciences of the United States of America. 112: E4374-80. PMID 26216999 DOI: 10.1073/Pnas.1512986112  0.796
2015 Sevostyanova A, Groisman EA, Roberts JW. An RNA motif advances transcription by preventing Rho-dependent termination Proceedings of the National Academy of Sciences of the United States of America. 112: E6835-E6843. DOI: 10.1073/pnas.1515383112  0.452
2015 Tan C, Ma J, Bird JG, Inman JT, Roberts JW, Wang MD. The Mechanism of Transcription Stalling under Torsion Biophysical Journal. 108: 536a. DOI: 10.1016/J.Bpj.2014.11.2938  0.549
2014 Roberts JW. Molecular biology. Molecular basis of transcription pausing. Science (New York, N.Y.). 344: 1226-7. PMID 24926002 DOI: 10.1126/Science.1255712  0.552
2014 Strobel EJ, Roberts JW. Regulation of promoter-proximal transcription elongation: enhanced DNA scrunching drives λQ antiterminator-dependent escape from a σ70-dependent pause. Nucleic Acids Research. 42: 5097-108. PMID 24550164 DOI: 10.1093/Nar/Gku147  0.82
2011 Perdue SA, Roberts JW. Σ(70)-dependent transcription pausing in Escherichia coli. Journal of Molecular Biology. 412: 782-92. PMID 21316374 DOI: 10.1016/J.Jmb.2011.02.011  0.564
2010 Perdue SA, Roberts JW. A backtrack-inducing sequence is an essential component of Escherichia coli σ(70)-dependent promoter-proximal pausing. Molecular Microbiology. 78: 636-50. PMID 21382107 DOI: 10.1111/J.1365-2958.2010.07347.X  0.514
2010 Roberts JW. Molecular biology. Syntheses that stay together. Science (New York, N.Y.). 328: 436-7. PMID 20413480 DOI: 10.1126/Science.1189971  0.459
2009 Roberts JW. Promoter-specific control of E. coli RNA polymerase by ppGpp and a general transcription factor. Genes & Development. 23: 143-6. PMID 19171778 DOI: 10.1101/Gad.1770509  0.592
2008 Roberts JW, Shankar S, Filter JJ. RNA polymerase elongation factors. Annual Review of Microbiology. 62: 211-33. PMID 18729732 DOI: 10.1146/Annurev.Micro.61.080706.093422  0.699
2008 Hatoum A, Roberts J. Prevalence of RNA polymerase stalling at Escherichia coli promoters after open complex formation. Molecular Microbiology. 68: 17-28. PMID 18333883 DOI: 10.1111/J.1365-2958.2008.06138.X  0.794
2007 Shankar S, Hatoum A, Roberts JW. A transcription antiterminator constructs a NusA-dependent shield to the emerging transcript. Molecular Cell. 27: 914-27. PMID 17889665 DOI: 10.1016/J.Molcel.2007.07.025  0.777
2006 Roberts JW. Biochemistry. RNA polymerase, a scrunching machine. Science (New York, N.Y.). 314: 1097-8. PMID 17110563 DOI: 10.1126/Science.1135746  0.512
2006 Nickels BE, Roberts CW, Roberts JW, Hochschild A. RNA-mediated destabilization of the sigma(70) region 4/beta flap interaction facilitates engagement of RNA polymerase by the Q antiterminator. Molecular Cell. 24: 457-68. PMID 17081994 DOI: 10.1016/J.Molcel.2006.09.014  0.53
2006 Holmes SF, Santangelo TJ, Cunningham CK, Roberts JW, Erie DA. Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity. The Journal of Biological Chemistry. 281: 18677-83. PMID 16621791 DOI: 10.1074/Jbc.M600543200  0.707
2006 Park JS, Roberts JW. Role of DNA bubble rewinding in enzymatic transcription termination. Proceedings of the National Academy of Sciences of the United States of America. 103: 4870-5. PMID 16551743 DOI: 10.1073/Pnas.0600145103  0.698
2005 Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, ... ... Roberts JW, et al. An open letter to Elias Zerhouni. Science (New York, N.Y.). 307: 1409-10. PMID 15746409 DOI: 10.1126/Science.307.5714.1409C  0.648
2004 Shundrovsky A, Santangelo TJ, Roberts JW, Wang MD. A single-molecule technique to study sequence-dependent transcription pausing. Biophysical Journal. 87: 3945-53. PMID 15465875 DOI: 10.1529/Biophysj.104.044081  0.701
2004 Guo J, Roberts JW. DNA binding regions of Q proteins of phages lambda and phi80. Journal of Bacteriology. 186: 3599-608. PMID 15150248 DOI: 10.1128/Jb.186.11.3599-3608.2004  0.462
2004 Santangelo TJ, Roberts JW. Forward translocation is the natural pathway of RNA release at an intrinsic terminator. Molecular Cell. 14: 117-26. PMID 15068808 DOI: 10.1016/S1097-2765(04)00154-6  0.752
2004 Roberts J, Park JS. Mfd, the bacterial transcription repair coupling factor: translocation, repair and termination. Current Opinion in Microbiology. 7: 120-5. PMID 15063847 DOI: 10.1016/J.Mib.2004.02.014  0.685
2004 Marr MT, Roberts JW, Brown SE, Klee M, Gussin GN. Interactions among CII protein, RNA polymerase and the lambda PRE promoter: contacts between RNA polymerase and the -35 region of PRE are identical in the presence and absence of CII protein. Nucleic Acids Research. 32: 1083-90. PMID 14872063 DOI: 10.1093/Nar/Gkh261  0.551
2003 Santangelo TJ, Roberts JW. Formation of long DNA templates containing site-specific alkane-disulfide DNA interstrand cross-links for use in transcription reactions. Methods in Enzymology. 371: 120-32. PMID 14712695 DOI: 10.1016/S0076-6879(03)71008-8  0.722
2003 Ryder AM, Roberts JW. Role of the non-template strand of the elongation bubble in intrinsic transcription termination. Journal of Molecular Biology. 334: 205-13. PMID 14607113 DOI: 10.1016/J.Jmb.2003.09.039  0.584
2003 Santangelo TJ, Mooney RA, Landick R, Roberts JW. RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins. Genes & Development. 17: 1281-92. PMID 12756229 DOI: 10.1101/Gad.1082103  0.754
2002 Nickels BE, Roberts CW, Sun H, Roberts JW, Hochschild A. The sigma(70) subunit of RNA polymerase is contacted by the (lambda)Q antiterminator during early elongation. Molecular Cell. 10: 611-22. PMID 12408828 DOI: 10.1016/S1097-2765(02)00648-2  0.64
2002 Adelman K, La Porta A, Santangelo TJ, Lis JT, Roberts JW, Wang MD. Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior. Proceedings of the National Academy of Sciences of the United States of America. 99: 13538-43. PMID 12370445 DOI: 10.1073/Pnas.212358999  0.769
2002 Park JS, Marr MT, Roberts JW. E. coli Transcription repair coupling factor (Mfd protein) rescues arrested complexes by promoting forward translocation. Cell. 109: 757-67. PMID 12086674 DOI: 10.1016/S0092-8674(02)00769-9  0.701
2002 Santangelo TJ, Roberts JW. RfaH, a bacterial transcription antiterminator. Molecular Cell. 9: 698-700. PMID 11983161 DOI: 10.1016/S1097-2765(02)00516-6  0.779
2001 Marr MT, Datwyler SA, Meares CF, Roberts JW. Restructuring of an RNA polymerase holoenzyme elongation complex by lambdoid phage Q proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 8972-8. PMID 11481468 DOI: 10.1073/Pnas.161253298  0.549
2000 Marr MT, Roberts JW. Function of transcription cleavage factors GreA and GreB at a regulatory pause site. Molecular Cell. 6: 1275-85. PMID 11163202 DOI: 10.1016/S1097-2765(00)00126-X  0.61
1999 Sharp MM, Chan CL, Lu CZ, Marr MT, Nechaev S, Merritt EW, Severinov K, Roberts JW, Gross CA. The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized. Genes & Development. 13: 3015-26. PMID 10580008 DOI: 10.1101/Gad.13.22.3015  0.424
1999 Yarnell WS, Roberts JW. Mechanism of intrinsic transcription termination and antitermination. Science (New York, N.Y.). 284: 611-5. PMID 10213678 DOI: 10.1126/Science.284.5414.611  0.567
1998 Ko DC, Marr MT, Guo J, Roberts JW. A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein. Genes & Development. 12: 3276-85. PMID 9784501 DOI: 10.1101/Gad.12.20.3276  0.546
1997 Marr MT, Roberts JW. Promoter recognition as measured by binding of polymerase to nontemplate strand oligonucleotide. Science (New York, N.Y.). 276: 1258-60. PMID 9157885 DOI: 10.1126/Science.276.5316.1258  0.586
1996 Severinova E, Severinov K, Fenyö D, Marr M, Brody EN, Roberts JW, Chait BT, Darst SA. Domain organization of the Escherichia coli RNA polymerase sigma 70 subunit. Journal of Molecular Biology. 263: 637-47. PMID 8947564 DOI: 10.1006/Jmbi.1996.0604  0.513
1996 Roberts CW, Roberts JW. Base-specific recognition of the nontemplate strand of promoter DNA by E. coli RNA polymerase. Cell. 86: 495-501. PMID 8756731 DOI: 10.1016/S0092-8674(00)80122-1  0.544
1996 Ring BZ, Yarnell WS, Roberts JW. Function of E. coli RNA polymerase sigma factor sigma 70 in promoter-proximal pausing. Cell. 86: 485-93. PMID 8756730 DOI: 10.1016/S0092-8674(00)80121-X  0.626
1996 Landick R, Roberts JW. The shrewd grasp of RNA polymerase. Science (New York, N.Y.). 273: 202-3. PMID 8668996 DOI: 10.1126/Science.273.5272.202  0.512
1995 Kainz M, Roberts JW. Kinetics of RNA polymerase initiation and pausing at the lambda late gene promoter in vivo. Journal of Molecular Biology. 254: 808-14. PMID 7500352 DOI: 10.1006/Jmbi.1995.0657  0.516
1994 Hart CM, Roberts JW. Deletion analysis of the lambda tR1 termination region. Effect of sequences near the transcript release sites, and the minimum length of rho-dependent transcripts. Journal of Molecular Biology. 237: 255-65. PMID 8145240 DOI: 10.1006/Jmbi.1994.1229  0.528
1994 Ring BZ, Roberts JW. Function of a nontranscribed DNA strand site in transcription elongation. Cell. 78: 317-24. PMID 8044843 DOI: 10.1016/0092-8674(94)90300-X  0.621
1994 McDowell JC, Roberts JW, Jin DJ, Gross C. Determination of intrinsic transcription termination efficiency by RNA polymerase elongation rate. Science (New York, N.Y.). 266: 822-5. PMID 7526463 DOI: 10.1126/Science.7526463  0.563
1993 Roberts JW. RNA and protein elements of E. coli and lambda transcription antitermination complexes. Cell. 72: 653-5. PMID 8453661 DOI: 10.1016/0092-8674(93)90394-6  0.507
1992 Kainz M, Roberts J. Structure of transcription elongation complexes in vivo. Science (New York, N.Y.). 255: 838-41. PMID 1536008 DOI: 10.1126/Science.1536008  0.593
1992 Yarnell WS, Roberts JW. The phage lambda gene Q transcription antiterminator binds DNA in the late gene promoter as it modifies RNA polymerase. Cell. 69: 1181-9. PMID 1535556 DOI: 10.1016/0092-8674(92)90639-T  0.559
1992 Roberts J. 15 Antitermination and the Control of Transcription Elongation Cold Spring Harbor Monograph Archive. 389-406. DOI: 10.1101/087969425.22A.389  0.555
1991 Guo HC, Roberts JW. Heterogeneous initiation due to slippage at the bacteriophage 82 late gene promoter in vitro. Biochemistry. 29: 10702-9. PMID 2271677 DOI: 10.1021/Bi00499A019  0.531
1991 Hart CM, Roberts JW. Rho-dependent transcription termination. Characterization of the requirement for cytidine in the nascent transcript. The Journal of Biological Chemistry. 266: 24140-8. PMID 1721066  0.463
1991 Sassanfar M, Roberts J. Constitutive and UV-mediated activation of RecA protein: combined effects of recA441 and recF143 mutations and of addition of nucleosides and adenine. Journal of Bacteriology. 173: 5869-75. PMID 1715863 DOI: 10.1128/Jb.173.18.5869-5875.1991  0.385
1991 Guo HC, Kainz M, Roberts JW. Characterization of the late-gene regulatory region of phage 21. Journal of Bacteriology. 173: 1554-60. PMID 1704887 DOI: 10.1128/Jb.173.4.1554-1560.1991  0.491
1990 Hurd HK, Roberts JW. Upstream regulatory sequences of the yeast RNR2 gene include a repression sequence and an activation site that binds the RAP1 protein. Molecular and Cellular Biology. 9: 5359-72. PMID 2685560 DOI: 10.1128/Mcb.9.12.5359  0.474
1990 Goliger JA, Roberts JW. Sequences required for antitermination by phage 82 Q protein. Journal of Molecular Biology. 210: 461-71. PMID 2559207 DOI: 10.1016/0022-2836(89)90123-X  0.555
1990 Sassanfar M, Roberts JW. Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication. Journal of Molecular Biology. 212: 79-96. PMID 2108251 DOI: 10.1016/0022-2836(90)90306-7  0.414
1989 Yang XJ, Goliger JA, Roberts JW. Specificity and mechanism of antitermination by Q proteins of bacteriophages lambda and 82. Journal of Molecular Biology. 210: 453-60. PMID 2559206 DOI: 10.1016/0022-2836(89)90122-8  0.501
1989 Yang XJ, Roberts JW. Gene Q antiterminator proteins of Escherichia coli phages 82 and lambda suppress pausing by RNA polymerase at a rho-dependent terminator and at other sites. Proceedings of the National Academy of Sciences of the United States of America. 86: 5301-5. PMID 2526335 DOI: 10.1073/Pnas.86.14.5301  0.572
1989 Goliger JA, Yang XJ, Guo HC, Roberts JW. Early transcribed sequences affect termination efficiency of Escherichia coli RNA polymerase. Journal of Molecular Biology. 205: 331-41. PMID 2467004 DOI: 10.1016/0022-2836(89)90344-6  0.566
1988 Roberts JW. Phage lambda and the regulation of transcription termination. Cell. 52: 5-6. PMID 2449971 DOI: 10.1016/0092-8674(88)90523-5  0.46
1987 Hurd HK, Roberts CW, Roberts JW. Identification of the gene for the yeast ribonucleotide reductase small subunit and its inducibility by methyl methanesulfonate Molecular and Cellular Biology. 7: 3673-3677. PMID 3316984 DOI: 10.1128/Mcb.7.10.3673  0.394
1987 Yang XJ, Hart CM, Grayhack EJ, Roberts JW. Transcription antitermination by phage lambda gene Q protein requires a DNA segment spanning the RNA start site. Genes & Development. 1: 217-26. PMID 2960589 DOI: 10.1101/Gad.1.3.217  0.587
1985 Grayhack EJ, Yang XJ, Lau LF, Roberts JW. Phage lambda gene Q antiterminator recognizes RNA polymerase near the promoter and accelerates it through a pause site. Cell. 42: 259-69. PMID 2990726 DOI: 10.1016/S0092-8674(85)80121-5  0.735
1984 Lau LF, Roberts JW, Wu R, Georges F, Narang SA. A potential stem-loop structure and the sequence CAAUCAA in the transcript are insufficient to signal rho-dependent transcription termination at lambda tR1. Nucleic Acids Research. 12: 1287-99. PMID 6320123 DOI: 10.1093/Nar/12.2.1287  0.748
1983 Grayhack EJ, Roberts JW. The phage lambda Q gene product: activity of a transcription antiterminator in vitro. Cell. 30: 637-48. PMID 6215986 DOI: 10.1016/0092-8674(82)90260-4  0.568
1983 Lau LF, Roberts JW, Wu R. RNA polymerase pausing and transcript release at the lambda tR1 terminator in vitro. Journal of Biological Chemistry. 258: 9391-9397. DOI: 10.1016/s0021-9258(17)44680-1  0.423
1982 Roberts JW, Phizicky EM, Burbee DG, Roberts CW, Moreau PL. A brief consideration of the SOS inducing signal. Biochimie. 64: 805-7. PMID 6814531 DOI: 10.1016/S0300-9084(82)80133-8  0.623
1982 Lau LF, Roberts JW, Wu R. Transcription terminates at lambda tR1 in three clusters. Proceedings of the National Academy of Sciences of the United States of America. 79: 6171-5. PMID 6216477 DOI: 10.1073/Pnas.79.20.6171  0.716
1982 Jat P, Roberts JW, Cowie A, Kamen R. Comparison of the polyoma virus early and late promoters by transcription in vitro. Nucleic Acids Research. 10: 871-87. PMID 6174941 DOI: 10.1093/NAR/10.3.871  0.477
1981 Phizicky EM, Roberts JW. Induction of SOS functions: regulation of proteolytic activity of E. coli RecA protein by interaction with DNA and nucleoside triphosphate. Cell. 25: 259-67. PMID 7023697 DOI: 10.1016/0092-8674(81)90251-8  0.671
1981 Craig NL, Roberts JW. Function of nucleoside triphosphate and polynucleotide in Escherichia coli recA protein-directed cleavage of phage lambda repressor. The Journal of Biological Chemistry. 256: 8039-44. PMID 6455420  0.601
1981 Roberts JW, Roberts CW. Two mutations that alter the regulatory activity of E. coli recA protein Nature. 290: 422-424. PMID 6452577 DOI: 10.1038/290422A0  0.454
1980 Schechtman MG, Alegre JN, Roberts JW. Assay and characterization of late gene regulators of bacteriophages φ82 and λ Journal of Molecular Biology. 142: 269-288. PMID 6450836 DOI: 10.1016/0022-2836(80)90273-9  0.441
1980 Phizicky EM, Roberts JW. Kinetics of RecA protein-directed inactivation of repressors of phage lambda and phage P22. Journal of Molecular Biology. 139: 319-28. PMID 6449596 DOI: 10.1016/0022-2836(80)90133-3  0.607
1980 Schechtman MG, Snedeker JD, Roberts JW. Genetics and structure of the late gene regulatory region of phage 82. Virology. 105: 393-404. PMID 6448512 DOI: 10.1016/0042-6822(80)90040-9  0.422
1980 Craig NL, Roberts JW. E. coli recA protein-directed cleavage of phage lambda repressor requires polynucleotide. Nature. 283: 26-30. PMID 6444245 DOI: 10.1038/283026A0  0.653
1979 Roberts JW, Roberts CW, Craig NL, Phizicky EM. Activity of the Escherichia coli recA-gene product. Cold Spring Harbor Symposia On Quantitative Biology. 43: 917-20. PMID 158477 DOI: 10.1101/Sqb.1979.043.01.100  0.698
1978 Roberts JW, Roberts CW, Craig NL. Escherichia coli recA gene product inactivates phage lambda repressor. Proceedings of the National Academy of Sciences of the United States of America. 75: 4714-8. PMID 368796 DOI: 10.1073/Pnas.75.10.4714  0.626
1976 Roberts JW. Transcription termination and late control in phage lambda. Proceedings of the National Academy of Sciences of the United States of America. 72: 3300-4. PMID 1059112 DOI: 10.1073/Pnas.72.9.3300  0.407
1976 Roberts JW, Roberts CW, Hilliker S, Botstein D. Transcription Termination and Regulation in Bacteriophages P22 and Lambda Cold Spring Harbor Monograph Archive. 6: 707-718. DOI: 10.1101/087969115.6.707  0.528
1975 Roberts JW, Roberts CW. Proteolytic cleavage of bacteriophage lambda repressor in induction Proceedings of the National Academy of Sciences of the United States of America. 72: 147-151. PMID 1090931 DOI: 10.1073/Pnas.72.1.147  0.348
1969 Roberts JW. Promoter mutation in vitro. Nature. 223: 480-482. PMID 5796951 DOI: 10.1038/223480A0  0.451
1969 Roberts JW. Termination Factor for RNA Synthesis Nature. 224: 1168-1174. PMID 4902144 DOI: 10.1038/2241168A0  0.473
Show low-probability matches.