Thomas McCown - Publications

Affiliations: 
Neurobiology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroscience Biology, Virology Biology

47/104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bohlen MO, McCown TJ, Powell SK, El-Nahal H, Daw T, Basso MA, Sommer MA, Samulski RJ. AAV Capsid-Promoter Interactions in the Brain Translate from Rat to the Non-Human Primate. Human Gene Therapy. PMID 32940068 DOI: 10.1089/hum.2020.196  0.418
2020 Powell SK, Samulski RJ, McCown TJ. AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32213322 DOI: 10.1016/j.ymthe.2020.03.007  0.461
2017 Mandel RJ, Marmion DJ, Kirik D, Chu Y, Heindel C, McCown T, Gray SJ, Kordower JH. Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates. Acta Neuropathologica Communications. 5: 47. PMID 28619074 DOI: 10.1186/S40478-017-0451-7  0.31
2017 Weinberg MS, Criswell HE, Powell SK, Bhatt AP, McCown TJ. Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28202388 DOI: 10.1016/J.Ymthe.2017.01.016  0.306
2016 Powell SK, Khan N, Parker CL, Samulski RJ, Matsushima G, Gray SJ, McCown TJ. Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism. Gene Therapy. PMID 27628693 DOI: 10.1038/Gt.2016.62  0.481
2015 Hu P, Li Y, Sands MS, McCown T, Kafri T. Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors. Molecular Therapy. Methods & Clinical Development. 2: 15025. PMID 26229972 DOI: 10.1038/Mtm.2015.25  0.407
2015 Powell SK, Khan N, Parker C, Jude Samulski R, Matsushima G, Gray SJ, McCown TJ. 306. Characterization of a Novel Adeno-Associated Viral Vector with Preferential Oligodendrocyte Tropism Molecular Therapy. 23: S123-S124. DOI: 10.1016/S1525-0016(16)33915-6  0.335
2014 Kantor B, McCown T, Leone P, Gray SJ. Clinical applications involving CNS gene transfer. Advances in Genetics. 87: 71-124. PMID 25311921 DOI: 10.1016/B978-0-12-800149-3.00002-0  0.459
2013 Weinberg MS, Blake BL, McCown TJ. Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility. Experimental Neurology. 247: 429-37. PMID 23333565 DOI: 10.1016/j.expneurol.2013.01.011  0.305
2013 Weinberg MS, Samulski RJ, McCown TJ. Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology. 69: 82-8. PMID 22465202 DOI: 10.1016/j.neuropharm.2012.03.004  0.37
2013 Weinberg MS, McCown TJ. Current prospects and challenges for epilepsy gene therapy. Experimental Neurology. 244: 27-35. PMID 22008258 DOI: 10.1016/j.expneurol.2011.10.003  0.455
2011 Gray SJ, Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 21971848 DOI: 10.1002/0471142301.Ns0417S57  0.769
2011 Weinberg MS, Blake BL, Samulski RJ, McCown TJ. The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5. Gene Therapy. 18: 961-8. PMID 21490684 DOI: 10.1038/Gt.2011.49  0.46
2011 Gray SJ, Foti SB, Schwartz JW, Bachaboina L, Taylor-Blake B, Coleman J, Ehlers MD, Zylka MJ, McCown TJ, Samulski RJ. Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors. Human Gene Therapy. 22: 1143-53. PMID 21476867 DOI: 10.1089/Hum.2010.245  0.727
2011 McCown TJ. Adeno-Associated Virus (AAV) Vectors in the CNS. Current Gene Therapy. 11: 181-8. PMID 21453285  0.467
2011 Kantor B, Bayer M, Ma H, Samulski J, Li C, McCown T, Kafri T. Notable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 547-56. PMID 21157436 DOI: 10.1038/Mt.2010.277  0.516
2010 Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ. Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood-Brain Barrier (BBB). Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 570-578. PMID 28182880 DOI: 10.1038/mt.2009.292  0.363
2010 McCown TJ. The future of epilepsy treatment: focus on adeno-associated virus vector gene therapy. Drug News & Perspectives. 23: 281-6. PMID 20603651 DOI: 10.1358/dnp.2010.23.5.1468393  0.45
2010 Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ, Li W. Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB). Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 570-8. PMID 20040913 DOI: 10.1038/Mt.2009.292  0.363
2010 Koh MT, Haberman RP, Foti S, McCown TJ, Gallagher M. Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1016-25. PMID 20032967 DOI: 10.1038/Npp.2009.207  0.679
2009 Foti SB, Samulski RJ, McCown TJ. Delivering multiple gene products in the brain from a single adeno-associated virus vector. Gene Therapy. 16: 1314-9. PMID 19727140 DOI: 10.1038/Gt.2009.106  0.76
2009 McCown TJ. Adeno-associated virus vector-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 307-11. PMID 19332324 DOI: 10.1016/j.nurt.2009.01.004  0.473
2009 Foti SB, Russek SJ, Brooks-Kayal AR, McCown TJ. Viral vector gene therapy for epilepsy Neuromethods. 40: 235-250. DOI: 10.1007/978-1-60327-263-6_13  0.744
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Eugene Redmond D, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260. PMID 28178482 DOI: 10.1038/Mt.2008.100  0.308
2008 Bayer M, Kantor B, Cockrell A, Ma H, Zeithaml B, Li X, McCown T, Kafri T. A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1968-76. PMID 18797449 DOI: 10.1038/Mt.2008.199  0.419
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-60. PMID 18500254 DOI: 10.1038/mt.2008.100  0.308
2008 Zhou X, Zeng X, Fan Z, Li C, McCown T, Samulski RJ, Xiao X. Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 494-9. PMID 18180769 DOI: 10.1038/Sj.Mt.6300397  0.431
2007 Foti S, Haberman RP, Samulski RJ, McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo. Gene Therapy. 14: 1534-6. PMID 17713567 DOI: 10.1038/Sj.Gt.3303013  0.741
2006 Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 18428636 DOI: 10.1002/0471142301.ns0417s35  0.773
2006 McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 63-8. PMID 16730475 DOI: 10.1016/j.ymthe.2006.04.004  0.387
2005 McCown TJ. Adeno-associated virus (AAV) vectors in the CNS. Current Gene Therapy. 5: 333-8. PMID 15975010 DOI: 10.2174/1566523054064995  0.475
2005 Cockrell AS, Ma H, McCown T, Kluckman KD, Thresher RJ, Kafri T. 478. A HIV-1 Based Cross-Packaging System for FIV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.018  0.391
2004 McCown TJ. The clinical potential of antiepileptic gene therapy. Expert Opinion On Biological Therapy. 4: 1771-6. PMID 15500405 DOI: 10.1517/14712598.4.11.1771  0.426
2004 Haack K, Cockrell AS, Ma H, Israeli D, Ho SN, McCown TJ, Kafri T. Transactivator and structurally optimized inducible lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 585-96. PMID 15336658 DOI: 10.1016/J.Ymthe.2004.06.109  0.418
2004 Cockrell AS, Fu K, Ma H, McCown T, Kafri T. 69. Closing-in on the titer gap between transient transfection and packaging cell lines Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.004  0.416
2003 Haberman RP, Samulski RJ, McCown TJ. Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion. Nature Medicine. 9: 1076-80. PMID 12858168 DOI: 10.1038/nm901  0.455
2002 Haberman RP, McCown TJ. Regulation of gene expression in adeno-associated virus vectors in the brain. Methods (San Diego, Calif.). 28: 219-26. PMID 12413420 DOI: 10.1016/S1046-2023(02)00226-8  0.445
2002 Haberman R, Criswell H, Snowdy S, Ming Z, Breese G, Samulski R, McCown T. Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 495-500. PMID 12377191 DOI: 10.1006/Mthe.2002.0701  0.758
2002 Fu H, Samulski RJ, McCown TJ, Picornell YJ, Fletcher D, Muenzer J. Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 42-9. PMID 11786044 DOI: 10.1006/Mthe.2001.0514  0.408
2001 Xu K, Ma H, McCown TJ, Verma IM, Kafri T. Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 97-104. PMID 11162316 DOI: 10.1006/Mthe.2000.0238  0.364
2000 Haberman RP, McCown TJ, Samulski RJ. Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element. Journal of Virology. 74: 8732-9. PMID 10954575 DOI: 10.1128/Jvi.74.18.8732-8739.2000  0.471
1998 Haberman RP, McCown TJ, Samulski RJ. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Therapy. 5: 1604-11. PMID 10023439 DOI: 10.1038/Sj.Gt.3300782  0.564
1998 Bartlett JS, Samulski RJ, McCown TJ. Selective and rapid uptake of adeno-associated virus type 2 in brain. Human Gene Therapy. 9: 1181-6. PMID 9625257 DOI: 10.1089/hum.1998.9.8-1181  0.379
1997 Xiao X, McCown TJ, Li J, Breese GR, Morrow AL, Samulski RJ. Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity. Brain Research. 756: 76-83. PMID 9187316 DOI: 10.1016/S0006-8993(97)00120-0  0.376
1997 Xiao X, Li J, McCown TJ, Samulski RJ. Gene transfer by adeno-associated virus vectors into the central nervous system. Experimental Neurology. 144: 113-24. PMID 9126160 DOI: 10.1006/Exnr.1996.6396  0.433
1997 Samulski RJ, During MJ, Kaplitt MG, Xiao X, Redman G, McCown T. Adeno-associated virus vectors yield long-term expression and delivery of potentially therapeutic genes into non-dividing neuronal cells Journal of Neurovirology. 3: S72.  0.445
1996 McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Research. 713: 99-107. PMID 8724980 DOI: 10.1016/0006-8993(95)01488-8  0.454
Low-probability matches (unlikely to be authored by this person)
2006 Cockrell AS, Ma H, Fu K, McCown TJ, Kafri T. A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 276-84. PMID 16516556 DOI: 10.1016/J.Ymthe.2005.12.015  0.296
2013 Gray SJ, Nagabhushan Kalburgi S, McCown TJ, Jude Samulski R. Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates. Gene Therapy. 20: 450-9. PMID 23303281 DOI: 10.1038/Gt.2012.101  0.286
2021 Francis JS, Markov V, Wojtas ID, Gray S, McCown T, Samulski RJ, Figueroa M, Leone P. Preclinical biodistribution, tropism, and efficacy of oligotropic AAV/Olig001 in a mouse model of congenital white matter disease. Molecular Therapy. Methods & Clinical Development. 20: 520-534. PMID 33614826 DOI: 10.1016/j.omtm.2021.01.009  0.281
2020 Marmion DJ, Rutkowski AA, Chatterjee D, Hiller BM, Werner MH, Bezard E, Kirik D, McCown T, Gray SJ, Kordower JH. Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease. Neurobiology of Disease. 105184. PMID 33221532 DOI: 10.1016/j.nbd.2020.105184  0.275
2014 Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL. Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5824-34. PMID 24760842 DOI: 10.1523/Jneurosci.4733-13.2014  0.265
2010 Johnson JS, Li C, DiPrimio N, Weinberg MS, McCown TJ, Samulski RJ. Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. Journal of Virology. 84: 8888-902. PMID 20573820 DOI: 10.1128/Jvi.00687-10  0.232
1997 McCown TJ, Knapp DJ, Crews FT. Inferior collicular seizure generalization produces site-selective cortical induction of cyclooxygenase 2 (COX-2). Brain Research. 767: 370-4. PMID 9367271 DOI: 10.1016/S0006-8993(97)00773-7  0.221
2017 Kostoula C, Pascente R, Ravizza T, McCown T, Schoch S, Vezzani A, Becker AJ, van Loo KMJ. Development of In Vivo Imaging Tools for Investigating Astrocyte Activation in Epileptogenesis. Molecular Neurobiology. PMID 28669125 DOI: 10.1007/s12035-017-0660-x  0.221
1987 McCown TJ, Greenwood RS, Breese GR. Inferior collicular interactions with limbic seizure activity. Epilepsia. 28: 234-41. PMID 3582287 DOI: 10.1111/J.1528-1157.1987.Tb04213.X  0.219
1991 McCown TJ, Breese GR. Seizure interactions between the inferior collicular cortex and the deep prepiriform cortex. Epilepsy Research. 8: 21-9. PMID 2060500 DOI: 10.1016/0920-1211(91)90032-B  0.214
1986 Frye GD, McCown TJ, Breese GR, Peterson SL. GABAergic modulation of inferior colliculus excitability: role in the ethanol withdrawal audiogenic seizures. The Journal of Pharmacology and Experimental Therapeutics. 237: 478-85. PMID 3009788  0.214
1995 McCown TJ, Duncan GE, Johnson KB, Breese GR. Metabolic and functional mapping of the neural network subserving inferior collicular seizure generalization. Brain Research. 701: 117-28. PMID 8925273 DOI: 10.1016/0006-8993(95)00970-X  0.212
1984 McCown TJ, Greenwood RS, Frye GD, Breese GR. Electrically elicited seizures from the inferior colliculus: a potential site for the genesis of epilepsy? Experimental Neurology. 86: 527-42. PMID 6437856 DOI: 10.1016/0014-4886(84)90087-6  0.211
1990 McCown TJ, Breese GR. Effects of apamin and nicotinic acetylcholine receptor antagonists on inferior collicular seizures. European Journal of Pharmacology. 187: 49-58. PMID 2272353 DOI: 10.1016/0014-2999(90)90339-8  0.21
1987 McCown TJ, Givens BS, Breese GR. Amino acid influences on seizures elicited within the inferior colliculus. The Journal of Pharmacology and Experimental Therapeutics. 243: 603-8. PMID 2890759  0.207
1991 McCown TJ, Edgar PP, Schwartz RD, Breese GR. Unilateral kindling of the inferior collicular cortex does not transfer to the contralateral seizure sensitive site or alter [3H]flunitrazepam and [35S]TBPS binding. Epilepsy Research. 9: 132-8. PMID 1794349 DOI: 10.1016/0920-1211(91)90024-A  0.2
1983 Frye GD, McCown TJ, Breese GR. Characterization of susceptibility to audiogenic seizures in ethanol-dependent rats after microinjection of gamma-aminobutyric acid (GABA) agonists into the inferior colliculus, substantia nigra or medial septum. The Journal of Pharmacology and Experimental Therapeutics. 227: 663-70. PMID 6317842  0.187
1992 McCown TJ, Breese GR. The developmental profile of seizure genesis in the inferior collicular cortex of the rat: relevance to human neonatal seizures. Epilepsia. 33: 2-10. PMID 1733756 DOI: 10.1111/J.1528-1157.1992.Tb02275.X  0.186
1991 McCown TJ, Breese GR. The role of the inferior collicular cortex in the neonatal rat: sensorimotor modulation. Brain Research. Developmental Brain Research. 59: 1-5. PMID 2040074 DOI: 10.1016/0165-3806(91)90022-B  0.178
1991 McCown TJ, Duncan GE, Breese GR. Neuroanatomical characterization of inferior collicular seizure genesis: 2-deoxyglucose and stimulation mapping. Brain Research. 567: 25-32. PMID 1815827 DOI: 10.1016/0006-8993(91)91431-Y  0.177
1993 McCown TJ, Breese GR. A potential contribution to ethanol withdrawal kindling: reduced GABA function in the inferior collicular cortex. Alcoholism, Clinical and Experimental Research. 17: 1290-4. PMID 8116844 DOI: 10.1111/J.1530-0277.1993.Tb05243.X  0.175
1990 McCown TJ, Breese GR. Multiple withdrawals from chronic ethanol "kindles" inferior collicular seizure activity: evidence for kindling of seizures associated with alcoholism. Alcoholism, Clinical and Experimental Research. 14: 394-9. PMID 2378423 DOI: 10.1111/J.1530-0277.1990.Tb00492.X  0.155
2016 Francis JS, Wojtas I, Markov V, Gray SJ, McCown TJ, Samulski RJ, Bilaniuk LT, Wang DJ, De Vivo DC, Janson CG, Leone P. N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase. Neurobiology of Disease. PMID 27717881 DOI: 10.1016/J.Nbd.2016.10.001  0.155
1984 McCown TJ, Greenwood RS, Breese GR. Wild running seizures elicited by electrical stimulation of the inferior colliculus are marked by inferior colliculus afterdischarge which can spread to the cortex Federation Proceedings. 43: no. 1655.  0.154
2012 Hayes DM, Fee JR, McCown TJ, Knapp DJ, Breese GR, Cubero I, Carvajal F, Lerma-Cabrera JM, Navarro M, Thiele TE. Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice. Addiction Biology. 17: 338-50. PMID 21762289 DOI: 10.1111/J.1369-1600.2011.00336.X  0.145
1984 Breese GR, Frye GD, McCown TJ, Mueller RA. Comparison of the CNS effects induced by TRH and bicuculline after microinjection into medial septum, substantia nigra and inferior colliculus: absence of support for a GABA antagonist action for TRH. Pharmacology, Biochemistry, and Behavior. 21: 145-9. PMID 6431450 DOI: 10.1016/0091-3057(84)90144-8  0.136
1983 Frye GD, McCown TJ, Breese GR. Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. The Journal of Pharmacology and Experimental Therapeutics. 226: 720-5. PMID 6310080  0.133
1990 Mueller RA, McCown TJ, Hunt RD, Lundberg C, Breese GR. Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. Cellular and Molecular Neurobiology. 10: 327-36. PMID 2253261 DOI: 10.1007/Bf00711178  0.128
1980 McCown TJ, Barrett RJ. Development of tolerance to the rewarding effects of self-administered S(+)-amphetamine. Pharmacology, Biochemistry, and Behavior. 12: 137-41. PMID 7367457 DOI: 10.1016/0091-3057(80)90428-1  0.128
2008 Papadeas ST, Halloran C, McCown TJ, Breese GR, Blake BL. Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization. The Journal of Comparative Neurology. 511: 271-85. PMID 18785628 DOI: 10.1002/Cne.21835  0.122
1984 Breese GR, Baumeister AA, McCown TJ, Emerick SG, Frye GD, Crotty K, Mueller RA. Behavioral differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine. The Journal of Pharmacology and Experimental Therapeutics. 231: 343-54. PMID 6149306  0.115
1987 Hedner J, McCown TJ, Mueller RA, Hedner T, Jonason J, Breese GR. Respiratory stimulant effects by TRH into the mesencephalic region in the rat. Acta Physiologica Scandinavica. 130: 69-75. PMID 3109212 DOI: 10.1111/J.1748-1716.1987.Tb08113.X  0.114
1985 Hedner J, Mueller RA, Hedner T, McCown TJ, Breese GR. A centrally elicited respiratory stimulant effect by bombesin in the rat. European Journal of Pharmacology. 115: 21-9. PMID 4043233 DOI: 10.1016/0014-2999(85)90579-5  0.113
1995 Duncan GE, Breese GR, Criswell HE, McCown TJ, Herbert JS, Devaud LL, Morrow AL. Distribution of [3H]zolpidem binding sites in relation to messenger RNA encoding the alpha 1, beta 2 and gamma 2 subunits of GABAA receptors in rat brain. Neuroscience. 64: 1113-28. PMID 7753379 DOI: 10.1016/0306-4522(94)00433-6  0.112
1984 Breese GR, Baumeister AA, McCown TJ, Emerick SG, Frye GD, Mueller RA. Neonatal-6-hydroxydopamine treatment: model of susceptibility for self-mutilation in the Lesch-Nyhan syndrome. Pharmacology, Biochemistry, and Behavior. 21: 459-61. PMID 6436840 DOI: 10.1016/S0091-3057(84)80110-0  0.11
1985 McCown TJ, Frye GD, Breese GR. Evidence for site specific ethanol actions in the CNS. Alcohol and Drug Research. 6: 423-9. PMID 3939188  0.105
1986 McCown TJ, Hedner JA, Towle AC, Breese GR, Mueller RA. Brainstem localization of a thyrotropin-releasing hormone-induced change in respiratory function. Brain Research. 373: 189-96. PMID 3087573 DOI: 10.1016/0006-8993(86)90330-6  0.096
1989 McCown TJ, Breese GR. Mechanistic and functional divergence between thyrotropin-releasing hormone and RO 15-4513 interactions with ethanol. Alcoholism, Clinical and Experimental Research. 13: 660-3. PMID 2512820 DOI: 10.1111/J.1530-0277.1989.Tb00400.X  0.096
1998 Ming Z, McCown TJ, Criswell HE, Breese GR, Mueller RA. NMDAR1 SPLICING ALTERS THE EFFECTS OF ISOFLURANE ON NMDA RECEPTORS Anesthesiology. 89: 701A. DOI: 10.1097/00000542-199809130-00007  0.095
1997 Criswell HE, McCown TJ, Moy SS, Oxford GS, Mueller RA, Morrow AL, Breese GR. Action of zolpidem on responses to GABA in relation to mRNAs for GABA(A) receptor alpha subunits within single cells: evidence for multiple functional GABA(A) isoreceptors on individual neurons. Neuropharmacology. 36: 1641-52. PMID 9517435 DOI: 10.1016/S0028-3908(97)00169-X  0.094
1987 Duncan GE, Criswell HE, McCown TJ, Paul IA, Mueller RA, Breese GR. Behavioral and neurochemical responses to haloperidol and SCH-23390 in rats treated neonatally or as adults with 6-hydroxydopamine. The Journal of Pharmacology and Experimental Therapeutics. 243: 1027-34. PMID 3121842  0.094
1984 Breese GR, McCown TJ, Baumeister AA. L-DOPA-induced self-biting in rats treated with 6-hydroxydopamine (6-OHDA) as neonates: Model of self-mutilation observed in the Lesch-Nyhan syndrome Federation Proceedings. 43: no. 3762.  0.09
1995 Criswell HE, Simson PE, Knapp DJ, Devaud LL, McCown TJ, Duncan GE, Morrow AL, Breese GR. Effect of zolpidem on gamma-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions. The Journal of Pharmacology and Experimental Therapeutics. 273: 526-36. PMID 7714808  0.089
1993 Criswell HE, Simson PE, Duncan GE, McCown TJ, Herbert JS, Morrow AL, Breese GR. Molecular basis for regionally specific action of ethanol on gamma-aminobutyric acidA receptors: generalization to other ligand-gated ion channels. The Journal of Pharmacology and Experimental Therapeutics. 267: 522-37. PMID 8229784  0.083
1999 Criswell HE, McCown TJ, Ming Z, Mueller RA, Breese GR. Interactive role for neurosteroids in ethanol enhancement of gamma-aminobutyric acid-gated currents from dissociated substantia nigra reticulata neurons. The Journal of Pharmacology and Experimental Therapeutics. 291: 1054-9. PMID 10565824  0.083
1986 Duncan GE, Pilgrim C, Stumpf WE, McCown TJ, Breese GR, Mueller RA. High resolution autoradiographic determination of the topographic distribution of radioactivity in the hippocampal formation after injection of [1-14C]glucose or 2-deoxy[14C]glucose. Neuroscience. 17: 99-106. PMID 3960318 DOI: 10.1016/0306-4522(86)90228-9  0.077
1986 McCown TJ, Moray LJ, Kizer JS, Breese GR. Interactions between TRH and ethanol in the medial septum. Pharmacology, Biochemistry, and Behavior. 24: 1269-74. PMID 3088607 DOI: 10.1016/0091-3057(86)90183-8  0.069
1983 McCown TJ, Vogel RA, Breese GR. An efficient chronic conflict paradigm: lick suppression by incremental footshock. Pharmacology, Biochemistry, and Behavior. 18: 277-9. PMID 6132406 DOI: 10.1016/0091-3057(83)90376-3  0.069
1984 Breese GR, Coyle S, Towle AC, Mueller RA, McCown TJ, Frye GD. Ethanol-induced locomotor stimulation in rats after thyrotropin-releasing hormone. The Journal of Pharmacology and Experimental Therapeutics. 229: 731-7. PMID 6427448  0.065
1987 Hedner J, Hedner T, Breese GR, Lundell KH, Lundberg D, Lundström NR, Ostergaard E, McCown TJ, Mueller RA. Changes in cerebrospinal fluid homovanillic acid in children with Ondine's curse. Pediatric Pulmonology. 3: 131-5. PMID 2438632 DOI: 10.1002/Ppul.1950030216  0.064
1993 Breese GR, Morrow AL, Simson PE, Criswell HE, McCown TJ, Duncan GE, Keir WJ. The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 309-13. PMID 7538301  0.063
1983 McCown TJ, Mueller RA, Breese GR. Effects of anesthetics and electrical stimulation on nigrostriatal dopaminergic neurons. The Journal of Pharmacology and Experimental Therapeutics. 224: 489-93. PMID 6827473  0.063
1986 McCown TJ, Napier TC, Breese GR. Effects of chronic electrode implantation on dopaminergic neurons in vivo. Pharmacology, Biochemistry, and Behavior. 25: 63-9. PMID 3018796 DOI: 10.1016/0091-3057(86)90231-5  0.037
1980 Evans EA, Kwok R, McCown T. Calibration of beam deflection produced by cellular forces in the 10(-9)--10(-6) gram range. Cell Biophysics. 2: 99-112. PMID 6159091 DOI: 10.1007/BF02795837  0.019
1950 McCOWN TD. The genus Palaeoantropus and the problem of super specific differentiation among the Hominidae. Cold Spring Harbor Symposia On Quantitative Biology. 15: 87-96. PMID 14942700  0.013
1981 McCown TJ, Mueller RA, Breese GR. Comparisons of bupropion, amphetamine and methylphenidate on pre-synaptic dopamine metabolism Federation Proceedings. 40: 450.  0.01
1946 McCOWN TD. The amputation prosthesis; a new field for dynamical physical anthropology. American Journal of Physical Anthropology. 4: 255. PMID 20990841  0.01
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