Kenneth L. Tyler - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Microbiology Biology

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Stonedahl S, Leser JS, Clarke P, Potter H, Boyd TD, Tyler KL. Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival. Journal of Virology. e0180522. PMID 36802227 DOI: 10.1128/jvi.01805-22  0.424
2022 Matthews E, Beckham JD, Piquet AL, Tyler KL, Chauhan L, Pastula DM. Herpesvirus-Associated Encephalitis: an Update. Current Tropical Medicine Reports. 9: 92-100. PMID 36186545 DOI: 10.1007/s40475-022-00255-8  0.665
2022 Krett JD, Beckham JD, Tyler KL, Piquet AL, Chauhan L, Wallace CJ, Pastula DM, Kapadia RK. Neurology of Acute Viral Infections. The Neurohospitalist. 12: 632-646. PMID 36147750 DOI: 10.1177/19418744221104778  0.727
2022 Pastula DM, Copeland MJ, Hannan MC, Rapaka S, Kitani T, Kleiner E, Showler A, Yuen C, Ferriman EM, House J, O'Brien S, Burakoff A, Gupta B, Money KM, Matthews E, ... ... Tyler KL, et al. Two Cases of Monkeypox-Associated Encephalomyelitis - Colorado and the District of Columbia, July-August 2022. Mmwr. Morbidity and Mortality Weekly Report. 71: 1212-1215. PMID 36136957 DOI: 10.15585/mmwr.mm7138e1  0.714
2022 Tyler KL. The enigmatic links between Epstein-Barr virus infection and multiple sclerosis. The Journal of Clinical Investigation. 132. PMID 35499072 DOI: 10.1172/JCI160468  0.37
2022 Stonedahl S, Leser JS, Clarke P, Tyler KL. Depletion of Microglia in an Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death. Microbiology Spectrum. 10: e0068522. PMID 35412380 DOI: 10.1128/spectrum.00685-22  0.463
2022 Rudy MJ, Coughlan C, Hixon AM, Clarke P, Tyler KL. Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes. Microbiology Spectrum. e0245221. PMID 35170992 DOI: 10.1128/spectrum.02452-21  0.797
2022 Potter H, Kendall L, Boyd T, Sillau S, Bosco-Lauth A, Markham N, Fong D, Clarke P, Tyler K. GM-CSF Promotes Immune Response and Survival in a Mouse Model of COVID-19. Research Square. PMID 35118463 DOI: 10.21203/rs.3.rs-1213395/v1  0.345
2021 Tyler KL. The Link Between Alzheimer Disease and Herpes Simplex Virus Infection: Better Late Than Never, or Better Never Than Late? Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 34480291 DOI: 10.1007/s13311-021-01112-8  0.363
2021 Clarke P, Leser JS, Tyler KL. Intrinsic innate immune responses control viral growth and protect against neuronal death in an model of WNV-induced CNS disease. Journal of Virology. JVI0083521. PMID 34190599 DOI: 10.1128/JVI.00835-21  0.414
2021 Dionne KR, Tyler KL, Clarke P. Slice Culture Modeling of CNS Viral Infection. Methods in Molecular Biology (Clifton, N.J.). 2311: 109-130. PMID 34033080 DOI: 10.1007/978-1-0716-1437-2_8  0.796
2021 High B, Hixon AM, Tyler KL, Piquet AL, Pelak VS. Neurology and the COVID-19 Pandemic: Gathering Data for an Informed Response. Neurology. Clinical Practice. 11: e48-e63. PMID 33842072 DOI: 10.1212/CPJ.0000000000000908  0.76
2020 Stonedahl S, Clarke P, Tyler KL. The Role of Microglia during West Nile Virus Infection of the Central Nervous System. Vaccines. 8. PMID 32872152 DOI: 10.3390/Vaccines8030485  0.556
2020 Kapadia RK, Tyler KL, Pastula DM. Encephalitis in adults caused by herpes simplex virus. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 192: E919. PMID 32778604 DOI: 10.1503/Cmaj.191636  0.371
2020 Potter H, Boyd TD, Clarke P, Pelak VS, Tyler KL. Recruiting the innate immune system with GM-CSF to fight viral diseases, including West Nile Virus encephalitis and COVID-19. F1000research. 9: 345. PMID 32704352 DOI: 10.12688/F1000Research.23729.1  0.402
2020 Kapadia RK, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Eastern Equine Encephalitis (EEE). The Neurohospitalist. 10: 161-162. PMID 32549937 DOI: 10.1177/1941874420905762  0.309
2020 Koralnik IJ, Tyler KL. COVID-19: a global threat to the nervous system. Annals of Neurology. PMID 32506549 DOI: 10.1002/Ana.25807  0.469
2019 Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Usutu virus disease: a potential problem for North America? Journal of Neurovirology. PMID 31858483 DOI: 10.1007/S13365-019-00818-Y  0.746
2019 Gnann JW, Agrawal A, Hart J, Buitrago M, Carson P, Hanfelt-Goade D, Tyler K, Spotkov J, Freifeld A, Moore T, Reyno J, Masur H, Jester P, Dale I, Li Y, et al. Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. Emerging Infectious Diseases. 25: 2064-2073. PMID 31625835 DOI: 10.3201/Eid2511.190537  0.342
2019 Khan M, Beckham JD, Piquet AL, Tyler KL, Pastula DM. An Overview of Powassan Virus Disease. The Neurohospitalist. 9: 181-182. PMID 31534605 DOI: 10.1177/1941874419844888  0.725
2019 Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Seminars in Neurology. 39: 419-427. PMID 31533182 DOI: 10.1055/S-0039-1687839  0.721
2019 Hixon AM, Frost J, Rudy MJ, Messacar K, Clarke P, Tyler KL. Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review. Viruses. 11. PMID 31487952 DOI: 10.3390/V11090821  0.799
2019 Bonney S, Seitz S, Ryan CA, Jones KL, Clarke P, Tyler KL, Siegenthaler JA. Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis. Mbio. 10. PMID 31387911 DOI: 10.1128/Mbio.01675-19  0.821
2019 Hixon AM, Clarke P, Tyler KL. Contemporary circulating enterovirus D68 strains infect and undergo retrograde axonal transport in spinal motor neurons independent of sialic acid. Journal of Virology. PMID 31167912 DOI: 10.1128/Jvi.00578-19  0.805
2019 Clarke P, Zhuang Y, Berens HM, Leser JS, Tyler KL. Interferon-β contributes to astrocyte activation in the brain following reovirus infection. Journal of Virology. PMID 30814290 DOI: 10.1128/Jvi.02027-18  0.829
2018 Brown DM, Hixon AM, Oldfield LM, Zhang Y, Novotny M, Wang W, Das SR, Shabman RS, Tyler KL, Scheuermann RH. Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells. Mbio. 9. PMID 30327438 DOI: 10.1128/Mbio.01954-18  0.815
2018 Tyler KL. Acute Viral Encephalitis. The New England Journal of Medicine. 379: 557-566. PMID 30089069 DOI: 10.1056/Nejmra1708714  0.361
2018 Seitz S, Clarke P, Tyler KL. Pharmacologic depletion of microglia increases viral load in the brain and enhances mortality in murine models of Flavivirus-induced encephalitis. Journal of Virology. PMID 29899084 DOI: 10.1128/Jvi.00525-18  0.843
2018 Messacar K, Asturias EJ, Hixon AM, Van Leer-Buter C, Niesters HGM, Tyler KL, Abzug MJ, Dominguez SR. Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality. The Lancet. Infectious Diseases. PMID 29482893 DOI: 10.1016/S1473-3099(18)30094-X  0.781
2017 McGuinness I, Beckham JD, Tyler KL, Pastula DM. An Overview of Yellow Fever Virus Disease. The Neurohospitalist. 7: 157-158. PMID 28974992 DOI: 10.1177/1941874417708129  0.727
2017 Hixon AM, Clarke P, Tyler KL. Evaluating treatment efficacy in a mouse model of enterovirus D68 paralytic myelitis. The Journal of Infectious Diseases. PMID 28968718 DOI: 10.1093/Infdis/Jix468  0.787
2017 Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline has anti-inflammatory effects and reduces cytotoxicity in an ex vivo spinal cord slice culture model of West Nile virus infection. Journal of Virology. PMID 28878079 DOI: 10.1128/Jvi.00569-17  0.806
2017 Tyler KL, Roos KL. The Expanding Spectrum of Zika Virus Infections of the Nervous System. Jama Neurology. PMID 28806454 DOI: 10.1001/Jamaneurol.2017.1471  0.49
2017 Shives KD, Tyler KL, Beckham JD. Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis. Journal of Neuroimmunology. PMID 28291542 DOI: 10.1016/J.Jneuroim.2017.03.006  0.834
2017 Hixon AM, Yu G, Leser JS, Yagi S, Clarke P, Chiu CY, Tyler KL. A mouse model of paralytic myelitis caused by enterovirus D68. Plos Pathogens. 13: e1006199. PMID 28231269 DOI: 10.1371/Journal.Ppat.1006199  0.809
2017 Tyler KL, Vollmer TL. To PLEX or not to PLEX in natalizumab-associated PML. Neurology. PMID 28228561 DOI: 10.1212/Wnl.0000000000003747  0.331
2017 Duca LM, Beckham JD, Tyler KL, Pastula DM. Zika Virus Disease and Associated Neurologic Complications. Current Infectious Disease Reports. 19: 4. PMID 28220392 DOI: 10.1007/S11908-017-0557-X  0.726
2016 Smith DE, Beckham JD, Tyler KL, Pastula DM. Zika virus disease for neurologists. Neurology. Clinical Practice. 6: 515-522. PMID 28058206 DOI: 10.1212/CPJ.0000000000000307  0.713
2016 Pastula DM, Durrant JC, Smith DE, Beckham JD, Tyler KL. Zika Virus Disease for the Neurointensivist. Neurocritical Care. PMID 27995511 DOI: 10.1007/S12028-016-0333-Z  0.744
2016 Tyler KL, Pastula DM. Hepatitis E Virus and Guillain-Barré Syndrome. Jama Neurology. PMID 27820625 DOI: 10.1001/Jamaneurol.2016.3651  0.306
2016 Wilson M, Tyler KL. Emerging Diagnostic and Therapeutic Tools for Central Nervous System Infections. Jama Neurology. PMID 27695862 DOI: 10.1001/Jamaneurol.2016.3617  0.407
2016 White MK, Wollebo HS, Beckham JD, Tyler KL, Khalili K. Zika virus: An emergent neuropathological agent. Annals of Neurology. PMID 27464346 DOI: 10.1002/Ana.24748  0.742
2016 Pastula DM, Smith DE, Beckham JD, Tyler KL. An Overview of Zika Virus Disease. The Neurohospitalist. 6: 93-4. PMID 27366289 DOI: 10.1177/1941874416637409  0.735
2016 Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, ... ... Tyler KL, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 534: 538-543. PMID 27337340 DOI: 10.1038/Nature18283  0.434
2016 Zhuang Y, Berens-Norman HM, Leser JS, Clarke P, Tyler KL. Mitochondrial p53 contributes to reovirus-induced neuronal apoptosis and CNS injury in a mouse model of viral encephalitis. Journal of Virology. PMID 27307572 DOI: 10.1128/Jvi.00583-16  0.75
2016 Beckham JD, Pastula DM, Massey A, Tyler KL. Zika Virus as an Emerging Global Pathogen: Neurological Complications of Zika Virus. Jama Neurology. PMID 27183312 DOI: 10.1001/Jamaneurol.2016.0800  0.74
2016 Pastula DM, Smith DE, Beckham JD, Tyler KL. Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases. Journal of Neurovirology. PMID 26903031 DOI: 10.1007/s13365-016-0428-5  0.705
2015 Beckham JD, Tyler KL. Arbovirus Infections. Continuum (Minneapolis, Minn.). 21: 1599-611. PMID 26633778 DOI: 10.1212/CON.0000000000000240  0.742
2015 Tyler KL. Editorial Commentary: Failure of Adjunctive Valacyclovir to Improve Outcomes in Herpes Simplex Encephalitis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 61: 692-4. PMID 25956893 DOI: 10.1093/Cid/Civ373  0.315
2015 Tyler KL. Fingolimod and risk of varicella-zoster virus infection: back to the future with an old infection and a new drug. Jama Neurology. 72: 10-3. PMID 25420159 DOI: 10.1001/Jamaneurol.2014.3390  0.431
2014 Steiner I, Tyler KL. The toll (like receptor 3) to the pathogenesis of herpes simplex encephalitis. Neurology. 83: 1882-3. PMID 25339218 DOI: 10.1212/Wnl.0000000000001011  0.481
2014 Quick ED, Leser JS, Clarke P, Tyler KL. Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection. Journal of Virology. 88: 13005-14. PMID 25165111 DOI: 10.1128/Jvi.01994-14  0.826
2014 Oyer RJ, David Beckham J, Tyler KL. West Nile and St. Louis encephalitis viruses. Handbook of Clinical Neurology. 123: 433-47. PMID 25015498 DOI: 10.1016/B978-0-444-53488-0.00020-1  0.457
2014 Tyler KL. Current developments in understanding of West Nile virus central nervous system disease. Current Opinion in Neurology. 27: 342-8. PMID 24722324 DOI: 10.1097/Wco.0000000000000088  0.387
2014 Clarke P, Leser JS, Bowen RA, Tyler KL. Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases. Mbio. 5: e00902-14. PMID 24618253 DOI: 10.1128/Mbio.00902-14  0.512
2014 Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL. Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. Journal of Virology. 88: 1080-9. PMID 24198425 DOI: 10.1128/Jvi.02944-13  0.818
2013 Dionne KR, Tyler KL. Slice culture modeling of central nervous system (CNS) viral infection. Methods in Molecular Biology (Clifton, N.J.). 1078: 97-117. PMID 23975824 DOI: 10.1007/978-1-62703-640-5_9  0.803
2013 Nath A, Tyler KL. Novel approaches and challenges to treatment of central nervous system viral infections. Annals of Neurology. 74: 412-22. PMID 23913580 DOI: 10.1002/Ana.23988  0.464
2013 Davis LE, Oyer R, Beckham JD, Tyler KL. Elevated CSF cytokines in the Jarisch-Herxheimer reaction of general paresis. Jama Neurology. 70: 1060-4. PMID 23732875 DOI: 10.1001/Jamaneurol.2013.2120  0.693
2013 Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P. Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis. Journal of Virology. 87: 3447-60. PMID 23302889 DOI: 10.1128/Jvi.02324-12  0.832
2012 Beatman E, Oyer R, Shives KD, Hedman K, Brault AC, Tyler KL, Beckham JD. West Nile virus growth is independent of autophagy activation. Virology. 433: 262-72. PMID 22939285 DOI: 10.1016/J.Virol.2012.08.016  0.825
2012 Schittone SA, Dionne KR, Tyler KL, Clarke P. Activation of innate immune responses in the central nervous system during reovirus myelitis. Journal of Virology. 86: 8107-18. PMID 22623770 DOI: 10.1128/Jvi.00171-12  0.816
2012 Stankiewicz TR, Loucks FA, Schroeder EK, Nevalainen MT, Tyler KL, Aktories K, Bouchard RJ, Linseman DA. Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity. The Journal of Biological Chemistry. 287: 16835-48. PMID 22378792 DOI: 10.1074/Jbc.M111.302166  0.362
2012 Beckham JD, Tyler KL. Neuro-intensive care of patients with acute CNS infections. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 124-38. PMID 22102180 DOI: 10.1007/S13311-011-0086-5  0.756
2011 Wilson MR, Tyler KL. Issues and updates in emerging neurologic viral infections. Seminars in Neurology. 31: 245-53. PMID 21964843 DOI: 10.1055/S-0031-1287650  0.465
2011 Dionne KR, Galvin JM, Schittone SA, Clarke P, Tyler KL. Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection. Journal of Neurovirology. 17: 314-26. PMID 21671121 DOI: 10.1007/S13365-011-0038-1  0.817
2011 Berens HM, Tyler KL. The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis. Journal of Virology. 85: 3858-71. PMID 21307199 DOI: 10.1128/Jvi.01958-10  0.827
2011 Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL. A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition. Experimental Neurology. 228: 222-31. PMID 21241693 DOI: 10.1016/J.Expneurol.2011.01.006  0.835
2010 Beckham JD, Tuttle KD, Tyler KL. Caspase-3 activation is required for reovirus-induced encephalitis in vivo. Journal of Neurovirology. 16: 306-17. PMID 20626234 DOI: 10.3109/13550284.2010.499890  0.784
2010 Tyler KL, Leser JS, Phang TL, Clarke P. Gene expression in the brain during reovirus encephalitis. Journal of Neurovirology. 16: 56-71. PMID 20158406 DOI: 10.3109/13550280903586394  0.509
2010 Levi ME, Quan D, Ho JT, Kleinschmidt-Demasters BK, Tyler KL, Grazia TJ. Impact of rituximab-associated B-cell defects on West Nile virus meningoencephalitis in solid organ transplant recipients. Clinical Transplantation. 24: 223-8. PMID 19659514 DOI: 10.1111/J.1399-0012.2009.01044.X  0.333
2010 Nathanson N, Tyler KL. Pathogenesis of Viral Infections Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0219  0.476
2009 Blakely PK, Kleinschmidt-DeMasters BK, Tyler KL, Irani DN. Disrupted glutamate transporter expression in the spinal cord with acute flaccid paralysis caused by West Nile virus infection. Journal of Neuropathology and Experimental Neurology. 68: 1061-72. PMID 19918118 DOI: 10.1097/Nen.0B013E3181B8Ba14  0.447
2009 Tyler KL. Emerging viral infections of the central nervous system: part 2. Archives of Neurology. 66: 1065-74. PMID 19752295 DOI: 10.1001/archneurol.2009.189  0.398
2009 Tyler KL. Emerging viral infections of the central nervous system: part 1. Archives of Neurology. 66: 939-48. PMID 19667214 DOI: 10.1001/Archneurol.2009.153  0.506
2009 Miyamoto SD, Brown RD, Robinson BA, Tyler KL, Long CS, Debiasi RL. Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype. Journal of Cardiac Failure. 15: 529-39. PMID 19643365 DOI: 10.1016/J.Cardfail.2009.01.004  0.401
2009 Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL. Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. Journal of Virology. 83: 6161-70. PMID 19321603 DOI: 10.1128/Jvi.02488-08  0.833
2009 Beckham JD, Tuttle K, Tyler KL. Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection. Journal of Virology. 83: 5035-45. PMID 19279118 DOI: 10.1128/Jvi.02433-08  0.749
2009 Clarke P, Tyler KL. Apoptosis in animal models of virus-induced disease. Nature Reviews. Microbiology. 7: 144-55. PMID 19148180 DOI: 10.1038/Nrmicro2071  0.449
2009 Tyler KL. Neurological infections: advances in therapy, outcome, and prediction. The Lancet. Neurology. 8: 19-21. PMID 19081508 DOI: 10.1016/S1474-4422(08)70279-5  0.325
2008 Tyler KL. The 50th birthday of progressive multifocal leukoencephalopathy: New insights into pathogenesis. Annals of Neurology. 64: 359-61. PMID 18991349 DOI: 10.1002/Ana.21486  0.423
2008 Davis LE, Beckham JD, Tyler KL. North American encephalitic arboviruses. Neurologic Clinics. 26: 727-57, ix. PMID 18657724 DOI: 10.1016/J.Ncl.2008.03.012  0.758
2008 Bosque PJ, Tyler KL. Prions' travels - Feces and transmission of prion diseases Journal of Infectious Diseases. 198: 8-9. PMID 18505382 DOI: 10.1086/588194  0.362
2008 Goody RJ, Schittone SA, Tyler KL. Experimental reovirus-induced acute flaccid paralysis and spinal motor neuron cell death. Journal of Neuropathology and Experimental Neurology. 67: 231-9. PMID 18344914 DOI: 10.1097/Nen.0B013E31816564F0  0.832
2008 Tyler KL, Gilden DH. Clinical management of viral encephalitis Neurotropic Viral Infections. 347-361. DOI: 10.1017/CBO9780511541728.024  0.35
2007 Tyler KL, Beckham JD. Management of acute shingles (herpes zoster). Reviews in Neurological Diseases. 4: 203-8. PMID 18195672  0.659
2007 Beckham JD, Tyler KL. Infectious disease - developments in the field of Creutzfeldt-Jakob disease. Reviews in Neurological Diseases. 4: 168-72. PMID 17943072  0.644
2007 Goody RJ, Beckham JD, Rubtsova K, Tyler KL. JAK-STAT signaling pathways are activated in the brain following reovirus infection. Journal of Neurovirology. 13: 373-83. PMID 17849321 DOI: 10.1080/13550280701344983  0.78
2007 Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA. Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria. The Journal of Biological Chemistry. 282: 29296-304. PMID 17690097 DOI: 10.1074/Jbc.M702853200  0.706
2007 Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL. Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. Journal of Virology. 81: 6984-92. PMID 17475657 DOI: 10.1128/Jvi.00467-07  0.787
2007 Gilden DH, Mahalingam R, Cohrs RJ, Tyler KL. Herpesvirus infections of the nervous system. Nature Clinical Practice. Neurology. 3: 82-94. PMID 17279082 DOI: 10.1038/Ncpneuro0401  0.457
2007 Clarke P, Tyler KL. Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 12: 211-23. PMID 17136319 DOI: 10.1007/S10495-006-0528-4  0.393
2006 Davis LE, DeBiasi R, Goade DE, Haaland KY, Harrington JA, Harnar JB, Pergam SA, King MK, DeMasters BK, Tyler KL. West Nile virus neuroinvasive disease. Annals of Neurology. 60: 286-300. PMID 16983682 DOI: 10.1002/Ana.20959  0.469
2006 Debiasi RL, Tyler KL. West Nile virus meningoencephalitis. Nature Clinical Practice. Neurology. 2: 264-75. PMID 16932563 DOI: 10.1038/Ncpneuro0176  0.428
2006 Beckham JD, Tyler KL. Initial management of acute bacterial meningitis in adults: summary of IDSA guidelines. Reviews in Neurological Diseases. 3: 57-60. PMID 16819421  0.649
2006 Tyler KL, Pape J, Goody RJ, Corkill M, Kleinschmidt-DeMasters BK. CSF findings in 250 patients with serologically confirmed West Nile virus meningitis and encephalitis. Neurology. 66: 361-5. PMID 16382032 DOI: 10.1212/01.Wnl.0000195890.70898.1F  0.317
2006 Miyamoto SD, Robinson BA, Tyler KL, Brown RD, Long CS, DeBiasi RL. 84 Cell-Specific Responses In An Apoptotic Model Of Viral Myocarditis. Journal of Investigative Medicine. 54. DOI: 10.2310/6650.2005.X0004.83  0.487
2006 DeBiasi RL, Tyler KL. Viral meningitis and encephalitis Continuum Lifelong Learning in Neurology. 12: 58-94.  0.378
2005 Lapadat R, Debiasi RL, Johnson GL, Tyler KL, Shah I. Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory Architecture. Current Genomics. 6: 501-513. PMID 23335855 DOI: 10.2174/138920205775067675  0.365
2005 Le SS, Loucks FA, Udo H, Richardson-Burns S, Phelps RA, Bouchard RJ, Barth H, Aktories K, Tyler KL, Kandel ER, Heidenreich KA, Linseman DA. Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons. Journal of Neurochemistry. 94: 1025-39. PMID 16092944 DOI: 10.1111/J.1471-4159.2005.03252.X  0.347
2005 Goody RJ, Hoyt CC, Tyler KL. Reovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury. Experimental Neurology. 195: 379-90. PMID 16004984 DOI: 10.1016/J.Expneurol.2005.05.016  0.811
2005 Clarke P, Debiasi RL, Meintzer SM, Robinson BA, Tyler KL. Inhibition of NF-kappa B activity and cFLIP expression contribute to viral-induced apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 10: 513-24. PMID 15909114 DOI: 10.1007/S10495-005-1881-4  0.415
2005 Clarke P, Debiasi RL, Goody R, Hoyt CC, Richardson-Burns S, Tyler KL. Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation. Viral Immunology. 18: 89-115. PMID 15802955 DOI: 10.1089/Vim.2005.18.89  0.796
2005 Clarke P, Richardson-Burns SM, DeBiasi RL, Tyler KL. Mechanisms of apoptosis during reovirus infection. Current Topics in Microbiology and Immunology. 289: 1-24. PMID 15791949 DOI: 10.1007/3-540-27320-4_1  0.5
2005 Richardson-Burns SM, Tyler KL. Minocycline delays disease onset and mortality in reovirus encephalitis. Experimental Neurology. 192: 331-9. PMID 15755550 DOI: 10.1016/J.Expneurol.2004.11.015  0.522
2005 Hoyt CC, Richardson-Burns SM, Goody RJ, Robinson BA, Debiasi RL, Tyler KL. Nonstructural protein sigma1s is a determinant of reovirus virulence and influences the kinetics and severity of apoptosis induction in the heart and central nervous system. Journal of Virology. 79: 2743-53. PMID 15708993 DOI: 10.1128/Jvi.79.5.2743-2753.2005  0.81
2005 Weinberg A, Bloch KC, Li S, Tang YW, Palmer M, Tyler KL. Dual infections of the central nervous system with Epstein-Barr virus. The Journal of Infectious Diseases. 191: 234-7. PMID 15609233 DOI: 10.1086/426402  0.446
2005 Davis LE, Tyler KL. Molecular diagnosis of CNS viral infections Journal of Neurology, Neurosurgery and Psychiatry. 76: 10. PMID 15607987 DOI: 10.1136/Jnnp.2004.051698  0.46
2005 Gilden DH, Tyler KL. Herpesvirus Infection and Peripheral Neuropathy Peripheral Neuropathy. 2: 2117-2127. DOI: 10.1016/B978-0-7216-9491-7.50096-X  0.31
2004 Clarke P, Meintzer SM, Wang Y, Moffitt LA, Richardson-Burns SM, Johnson GL, Tyler KL. JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells. Journal of Virology. 78: 13132-8. PMID 15542665 DOI: 10.1128/Jvi.78.23.13132-13138.2004  0.439
2004 Debiasi RL, Tyler KL. Molecular methods for diagnosis of viral encephalitis. Clinical Microbiology Reviews. 17: 903-25, table of con. PMID 15489354 DOI: 10.1128/Cmr.17.4.903-925.2004  0.384
2004 DeBiasi RL, Robinson BA, Sherry B, Bouchard R, Brown RD, Rizeq M, Long C, Tyler KL. Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo. Journal of Virology. 78: 11040-50. PMID 15452224 DOI: 10.1128/Jvi.78.20.11040-11050.2004  0.475
2004 Tyler KL. Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. Herpes : the Journal of the Ihmf. 11: 57A-64A. PMID 15319091  0.334
2004 Kleinschmidt-DeMasters BK, Marder BA, Levi ME, Laird SP, McNutt JT, Escott EJ, Everson GT, Tyler KL. Naturally acquired West Nile virus encephalomyelitis in transplant recipients: clinical, laboratory, diagnostic, and neuropathological features. Archives of Neurology. 61: 1210-20. PMID 15313837 DOI: 10.1001/Archneur.61.8.1210  0.312
2004 Tyler KL. West Nile virus infection in the United States. Archives of Neurology. 61: 1190-5. PMID 15313835 DOI: 10.1001/Archneur.61.8.1190  0.409
2004 Tyler KL. COMMENTARY: Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC. Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J Infect Dis 1980; 142:205-208. The Journal of Infectious Diseases. 190: 653-60. PMID 15243947 DOI: 10.1086/422260  0.378
2004 Hoyt CC, Bouchard RJ, Tyler KL. Novel nuclear herniations induced by nuclear localization of a viral protein. Journal of Virology. 78: 6360-9. PMID 15163729 DOI: 10.1128/Jvi.78.12.6360-6369.2004  0.79
2004 Tyler KL, Barton ES, Ibach ML, Robinson C, Campbell JA, O'Donnell SM, Valyi-Nagy T, Clarke P, Wetzel JD, Dermody TS. Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis. The Journal of Infectious Diseases. 189: 1664-75. PMID 15116303 DOI: 10.1086/383129  0.574
2004 Richardson-Burns SM, Tyler KL. Regional differences in viral growth and central nervous system injury correlate with apoptosis. Journal of Virology. 78: 5466-75. PMID 15113925 DOI: 10.1128/Jvi.78.10.5466-5475.2004  0.503
2004 Edelmann KH, Richardson-Burns S, Alexopoulou L, Tyler KL, Flavell RA, Oldstone MB. Does Toll-like receptor 3 play a biological role in virus infections? Virology. 322: 231-8. PMID 15110521 DOI: 10.1016/J.Virol.2004.01.033  0.455
2003 Tyler KL. The uninvited guest: JC virus infection of neurons in PML. Neurology. 61: 734-5. PMID 14504312 DOI: 10.1212/Wnl.61.6.734  0.461
2003 DeBiasi RL, Clarke P, Meintzer S, Jotte R, Kleinschmidt-Demasters BK, Johnson GL, Tyler KL. Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis. Journal of Virology. 77: 8934-47. PMID 12885910 DOI: 10.1128/Jvi.77.16.8934-8947.2003  0.489
2003 Gonzales N, Tyler KL, Gilden DH. Recurrent dermatomal vesicular skin lesions: a clue to diagnosis of herpes simplex virus 2 meningitis. Archives of Neurology. 60: 868-9. PMID 12810492 DOI: 10.1001/Archneur.60.6.868  0.332
2003 Clarke P, Tyler KL. Reovirus-induced apoptosis: A minireview Apoptosis. 8: 141-150. PMID 12766474 DOI: 10.1023/A:1022966508671  0.483
2003 Clarke P, Meintzer SM, Moffitt LA, Tyler KL. Two distinct phases of virus-induced nuclear factor kappa B regulation enhance tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in virus-infected cells. The Journal of Biological Chemistry. 278: 18092-100. PMID 12637521 DOI: 10.1074/Jbc.M300265200  0.458
2003 Malessa R, Tyler KL. Acute Viral Infections of the Central Nervous System Neurological Disorders: Course and Treatment: Second Edition. 601-613. DOI: 10.1016/B978-012125831-3/50244-6  0.413
2002 Mann MA, Tyler KL, Knipe DM, Fields BN. Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Virology. 303: 213-21. PMID 12490384 DOI: 10.1006/Viro.2002.1698  0.579
2002 Richardson-Burns SM, Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL. Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS. Archives of Neurology. 59: 1930-6. PMID 12470182 DOI: 10.1001/Archneur.59.12.1930  0.429
2002 DeBiasi RL, Kleinschmidt-DeMasters BK, Richardson-Burns S, Tyler KL. Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis. The Journal of Infectious Diseases. 186: 1547-57. PMID 12447729 DOI: 10.1086/345375  0.442
2002 Weinberg A, Li S, Palmer M, Tyler KL. Quantitative CSF PCR in Epstein-Barr virus infections of the central nervous system. Annals of Neurology. 52: 543-8. PMID 12402250 DOI: 10.1002/Ana.10321  0.386
2002 Richardson-Burns SM, Kominsky DJ, Tyler KL. Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. Journal of Neurovirology. 8: 365-80. PMID 12402163 DOI: 10.1080/13550280260422677  0.451
2002 Kominsky DJ, Bickel RJ, Tyler KL. Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels. Journal of Virology. 76: 11414-24. PMID 12388702 DOI: 10.1128/Jvi.76.22.11414-11424.2002  0.406
2002 Kominsky DJ, Bickel RJ, Tyler KL. Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death Cell Death and Differentiation. 9: 926-933. PMID 12181743 DOI: 10.1038/Sj.Cdd.4401045  0.416
2002 DeBiasi RL, Kleinschmidt-DeMasters BK, Weinberg A, Tyler KL. Use of PCR for the diagnosis of herpesvirus infections of the central nervous system. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 25: S5-11. PMID 12091076 DOI: 10.1016/S1386-6532(02)00028-8  0.464
2002 Tyler KL, McArthur JC. Through a glass, darkly: cerebrospinal fluid viral load measurements and the pathogenesis of human immunodeficiency virus infection of the central nervous system. Archives of Neurology. 59: 909-12. PMID 12056925 DOI: 10.1001/Archneur.59.6.909  0.441
2002 Redington JJ, Tyler KL. Viral infections of the nervous system, 2002: update on diagnosis and treatment. Archives of Neurology. 59: 712-8. PMID 12020250 DOI: 10.1001/Archneur.59.5.712  0.442
2002 Poggioli GJ, DeBiasi RL, Bickel R, Jotte R, Spalding A, Johnson GL, Tyler KL. Reovirus-induced alterations in gene expression related to cell cycle regulation. Journal of Virology. 76: 2585-94. PMID 11861824 DOI: 10.1128/Jvi.76.6.2585-2594.2002  0.793
2002 Spalding AC, Jotte RM, Scheinman RI, Geraci MW, Clarke P, Tyler KL, Johnson GL. TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells. Oncogene. 21: 260-71. PMID 11803469 DOI: 10.1038/Sj.Onc.1205048  0.332
2001 Tyler KL, Clarke P, DeBiasi RL, Kominsky D, Poggioli GJ. Reoviruses and the host cell. Trends in Microbiology. 9: 560-4. PMID 11825717 DOI: 10.1016/S0966-842X(01)02103-5  0.809
2001 Clarke P, Meintzer SM, Widmann C, Johnson GL, Tyler KL. Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun Journal of Virology. 75: 11275-11283. PMID 11689607 DOI: 10.1128/Jvi.75.23.11275-11283.2001  0.418
2001 Clarke P, Meintzer SM, Spalding AC, Johnson GL, Tyler KL. Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection. Oncogene. 20: 6910-9. PMID 11687970 DOI: 10.1038/Sj.Onc.1204842  0.385
2001 Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL. Polymerase chain reaction as a diagnostic adjunct in herpesvirus infections of the nervous system. Brain Pathology (Zurich, Switzerland). 11: 452-64. PMID 11556691 DOI: 10.1111/J.1750-3639.2001.Tb00414.X  0.353
2001 Poggioli GJ, Dermody TS, Tyler KL. Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2). Journal of Virology. 75: 7429-34. PMID 11462015 DOI: 10.1128/Jvi.75.16.7429-7434.2001  0.784
2001 Tyler KL. West nile virus encephalitis in America New England Journal of Medicine. 344: 1858-1859. PMID 11407349 DOI: 10.1056/Nejm200106143442409  0.442
2001 DeBiasi RL, Edelstein CL, Sherry B, Tyler KL. Calpain inhibition protects against virus-induced apoptotic myocardial injury Journal of Virology. 75: 351-361. PMID 11119604 DOI: 10.1128/Jvi.75.1.351-361.2001  0.493
2000 Poggioli GJ, Keefer C, Connolly JL, Dermody TS, Tyler KL. Reovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis. Journal of Virology. 74: 9562-70. PMID 11000227 DOI: 10.1128/Jvi.74.20.9562-9570.2000  0.788
2000 Clarke P, Meintzer SM, Gibson S, Widmann C, Garrington TP, Johnson GL, Tyler KL. Reovirus-induced apoptosis is mediated by TRAIL Journal of Virology. 74: 8135-8139. PMID 10933724 DOI: 10.1128/Jvi.74.17.8135-8139.2000  0.405
2000 Yujiri T, Ware M, Widmann C, Oyer R, Russell D, Chan E, Zaitsu Y, Clarke P, Tyler K, Oka Y, Fanger GR, Henson P, Johnson GL. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation Proceedings of the National Academy of Sciences of the United States of America. 97: 7272-7277. PMID 10852963 DOI: 10.1073/Pnas.130176697  0.324
2000 Connolly JL, Rodgers SE, Clarke P, Ballard DW, Kerr LD, Tyler KL, Dermody TS. Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB. Journal of Virology. 74: 2981-9. PMID 10708412 DOI: 10.1128/Jvi.74.7.2981-2989.2000  0.589
1999 DeBiasi RL, Tyler KL. Polymerase chain reaction in the diagnosis and management of central nervous system infections Archives of Neurology. 56: 1215-1219. PMID 10520937 DOI: 10.1001/Archneur.56.10.1215  0.357
1999 Debiasi RL, Squier MKT, Pike B, Wynes M, Dermody TS, John Cohen J, Tyler KL. Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors Journal of Virology. 73: 695-701. PMID 9847375 DOI: 10.1128/Jvi.73.1.695-701.1999  0.598
1999 Tyler KL. Viral infections of the nervous system, 2nd ed Annals of Neurology. 45: 549-549. DOI: 10.1002/1531-8249(199904)45:4<549::Aid-Ana27>3.0.Co;2-D  0.478
1998 Pelosi E, Rozenberg F, Coen DM, Tyler KL. A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice Virology. 252: 364-372. PMID 9878615 DOI: 10.1006/Viro.1998.9447  0.405
1998 Kleinschmidt-DeMasters BK, Mahalingam R, Shimek C, Marcoux HL, Wellish M, Tyler KL, Gilden DH. Profound cerebrospinal fluid pleocytosis and Froin's Syndrome secondary to widespread necrotizing vasculitis in an HIV-positive patient with varicella zoster virus encephalomyelitis. Journal of the Neurological Sciences. 159: 213-8. PMID 9741410 DOI: 10.1016/S0022-510X(98)00171-3  0.37
1998 Fodor PA, Levin MJ, Weinberg A, Sandberg E, Sylman J, Tyler KL. Atypical herpex simplex virus encephalitis diagnosed by PCR amplification of viral DNA from CSF Neurology. 51: 554-559. PMID 9710034 DOI: 10.1212/Wnl.51.2.554  0.425
1998 Virgin HW, Dermody TS, Tyler KL. Cellular and humoral immunity to reovirus infection Current Topics in Microbiology and Immunology. 233: 147-161. PMID 9599936 DOI: 10.1007/978-3-642-72095-6_8  0.516
1998 Tyler KL. Pathogenesis of reovirus infections of the central nervous system Current Topics in Microbiology and Immunology. 233: 93-124. PMID 9599934 DOI: 10.1016/1044-5765(91)90006-A  0.488
1998 Oberhaus SM, Dermody TS, Tyler KL. Apoptosis and the cytopathic effects of reovirus Current Topics in Microbiology and Immunology. 233: 23-49. PMID 9599930 DOI: 10.1007/978-3-642-72095-6_2  0.646
1997 Rodgers SE, Barton ES, Oberhaus SM, Pike B, Gibson CA, Tyler KL, Dermody TS. Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2. Journal of Virology. 71: 2540-6. PMID 9032397 DOI: 10.1128/Jvi.71.3.2540-2546.1997  0.608
1997 Oberhaus SM, Smith RL, Clayton GH, Dermody TS, Tyler KL. Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis Journal of Virology. 71: 2100-2106. PMID 9032342 DOI: 10.1128/Jvi.71.3.2100-2106.1997  0.654
1997 Dermody TS, Rodgers SE, Connolly JL, Tyler KL. Reovinis induces apoptosis by activation of the transcription factor NF-κB Clinical Infectious Diseases. 25: 355.  0.587
1996 Tyler KL, Squier MK, Brown AL, Pike B, Willis D, Oberhaus SM, Dermody TS, Cohen JJ. Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes. Journal of Virology. 70: 7984-91. PMID 8892922 DOI: 10.1128/Jvi.70.11.7984-7991.1996  0.568
1995 Tyler KL, Tedder DG, Yamamoto LJ, Klapper JA, Ashley R, Lichtenstein KA, Levin MJ. Recurrent brainstem encephalitis associated with herpes simplex virus type 1 DNA in cerebrospinal fluid Neurology. 45: 2246-2250. PMID 8848201 DOI: 10.1212/Wnl.45.12.2246  0.365
1995 Dermody TS, Chappell JD, Hofler JG, Kramp W, Tyler KL. Eradication of persistent reovirus infection from a B-cell hybridoma Virology. 212: 272-276. PMID 7676645 DOI: 10.1006/Viro.1995.1483  0.607
1995 Paskavitz JF, Anderson CA, Filley CM, Kleinschmidt-DeMasters BK, Tyler KL. Acute arcuate fiber demyelinating encephalopathy following Epstein-Barr virus infection. Annals of Neurology. 38: 127-31. PMID 7611716 DOI: 10.1002/Ana.410380121  0.445
1995 Tyler KL, Squier MKT, Rodgers SE, Schneider BE, Oberhaus SM, Grdina TA, Cohen JJ, Dermody TS. Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein σ1 Journal of Virology. 69: 6972-6979. PMID 7474116 DOI: 10.1128/Jvi.69.11.6972-6979.1995  0.638
1995 Tyler KL. Risk of human exposure to bovine spongiform encephalopathy British Medical Journal. 311: 1420-1421. DOI: 10.1136/Bmj.311.7017.1420  0.38
1994 Virgin IV HW, Mann MA, Tyler KL. Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases Journal of Virology. 68: 6719-6729. PMID 8084004 DOI: 10.1128/Jvi.68.10.6719-6729.1994  0.361
1994 Tedder DG, Ashley R, Tyler KL, Levin MJ. Herpes simplex virus infection as a cause of benign recurrent lymphocytic meningitis Annals of Internal Medicine. 121: 334-338. PMID 8042822 DOI: 10.7326/0003-4819-121-5-199409010-00004  0.359
1994 Tyler KL. Polymerase chain reaction and the diagnosis of viral central nervous system diseases Annals of Neurology. 36: 809-811. PMID 7998764 DOI: 10.1002/Ana.410360602  0.31
1993 Sherry B, Li XY, Tyler KL, Cullen JM, Virgin HW. Lymphocytes protect against and are not required for reovirus-induced myocarditis. Journal of Virology. 67: 6119-24. PMID 8396673 DOI: 10.1128/Jvi.67.10.6119-6124.1993  0.376
1993 Tyler KL, Mann MA, Fields BN, Virgin IV HW. Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis Journal of Virology. 67: 3446-3453. PMID 8388508 DOI: 10.1128/Jvi.67.6.3446-3453.1993  0.63
1993 Tyler KL. Molecular neurovirology: Pathogenesis of viral CNS infections Journal of the Neurological Sciences. 118: 223. DOI: 10.1016/0022-510X(93)90115-F  0.477
1991 Virgin IV HW, Mann MA, Fields BN, Tyler KL. Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action Journal of Virology. 65: 6772-6781. PMID 1719233 DOI: 10.1128/Jvi.65.12.6772-6781.1991  0.545
1991 Virgin IV HW, Tyler KL. Role of immune cells in protection against and control of reovirus infection in neonatal mice Journal of Virology. 65: 5157-5164. PMID 1654436 DOI: 10.1128/Jvi.65.10.5157-5164.1991  0.372
1989 Sacks SL, Wanklin RJ, Reece DE, Hicks KA, Tyler KL, Coen DM. Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? Annals of Internal Medicine. 111: 893-9. PMID 2554768 DOI: 10.7326/0003-4819-111-11-893  0.317
1989 Tyler KL, Virgin IVth HW, Bassel-Duby R, Fields BN. Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system Journal of Experimental Medicine. 170: 887-900. PMID 2549167 DOI: 10.1084/Jem.170.3.887  0.68
1989 Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proceedings of the National Academy of Sciences of the United States of America. 86: 4736-40. PMID 2543985 DOI: 10.1073/Pnas.86.12.4736  0.465
1989 Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. Journal of Virology. 63: 759-68. PMID 2536101 DOI: 10.1128/Jvi.63.2.759-768.1989  0.386
1988 Lipkin WI, Tyler KL, Waksman BH. Viruses, the immune system and central nervous system diseases. Trends in Neurosciences. 11: 43-5. PMID 2465596 DOI: 10.1016/0166-2236(88)90160-9  0.361
1988 Virgin IV HW, Bassel-Duby R, Fields BN, Tyler KL. Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing) Journal of Virology. 62: 4594-4604. PMID 2460637 DOI: 10.1128/Jvi.62.12.4594-4604.1988  0.629
1987 Gonzalez-Scarano F, Tyler KL. Molecular pathogenesis of neurotropic viral infections Annals of Neurology. 22: 565-574. PMID 3322182 DOI: 10.1002/Ana.410220502  0.445
1987 Tyler KL, McPhee DA. Molecular and genetic aspects of the pathogenesis of viral infections of the central nervous system Critical Reviews in Neurobiology. 3: 221-243. PMID 3315238  0.376
1987 Tyler KL. Host and viral factors that influence viral neurotropism II. Viral genes, host genes, site of entry and route of spread of virus Trends in Neurosciences. 10: 492-497. DOI: 10.1016/0166-2236(87)90127-5  0.434
1987 Tyler KL. Host and viral factors that influence viral neurotropism I. Viral cell attachment proteins and target cell receptors Trends in Neurosciences. 10: 455-460. DOI: 10.1016/0166-2236(87)90098-1  0.443
1986 Tyler KL, McPhee DA, Fields BN. Distinct pathways of viral spread in the host determined by reovirus S1 gene segment Science. 233: 770-774. PMID 3016895 DOI: 10.1126/Science.3016895  0.604
1986 Kaye KM, Spriggs DR, Bassel-Duby R, Fields BN, Tyler KL. Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing) Journal of Virology. 59: 90-97. PMID 3012122 DOI: 10.1128/Jvi.59.1.90-97.1986  0.563
1986 Tyler KL, Gross RA, Cascino GD. Unusual viral causes of transverse myelitis: hepatitis A virus and cytomegalovirus. Neurology. 36: 855-8. PMID 3010183 DOI: 10.1212/Wnl.36.6.855  0.472
1986 Bassel-Duby R, Spriggs DR, Tyler KL, Fields BN. Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique. Journal of Virology. 60: 64-67. DOI: 10.1128/Jvi.60.1.64-67.1986  0.585
1985 Tyler KL, Bronson RT, Byers KB, Fields B. Molecular basis of viral neurotropism: Experimental reo virus infection Neurology. 35: 88-92. PMID 2981418 DOI: 10.1212/Wnl.35.1.88  0.669
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