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David A. Ornelles - Publications

Affiliations: 
Wake Forest University, Winston-Salem, NC, United States 
Area:
Microbiology Biology
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kim TE, Puckett S, Zhang K, Herpai DM, Ornelles DA, Davis JN, van den Pol AN, Debinski W, Lyles DS. Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells. Molecular Therapy Oncolytics. 22: 232-244. PMID 34514102 DOI: 10.1016/j.omto.2021.06.003  0.351
2020 Bayne RS, Puckett S, Rodrigues LU, Cramer SD, Lee J, Furdui CM, Chou JW, Miller LD, Ornelles DA, Lyles DS. and Are Novel Mediators of Resistance to Oncolytic Vesicular Stomatitis Virus in Prostate Cancer Cells. Molecular Therapy Oncolytics. 17: 496-507. PMID 32529027 DOI: 10.1016/J.Omto.2020.05.004  0.442
2019 Lynch KL, Gooding LR, Garnett-Benson C, Ornelles DA, Avgousti DC. Epigenetics and the dynamics of chromatin during adenovirus infections. Febs Letters. PMID 31769503 DOI: 10.1002/1873-3468.13697  0.454
2018 Kaverina NV, Kadagidze ZG, Borovjagin AV, Karseladze AI, Kim CK, Lesniak MS, Miska J, Zhang P, Baryshnikova MA, Xiao T, Ornelles D, Cobbs C, Khramtsov A, Ulasov IV. Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX. Oncogene. PMID 29991800 DOI: 10.1038/S41388-018-0395-9  0.366
2017 Grayson KM, Blevins LK, Oliver MB, Ornelles D, Swords WE, Alexander-Miller MA. Activation-dependent modulation of Streptococcus pneumoniae mediated death in human lymphocytes. Pathogens and Disease. PMID 28158464 DOI: 10.1093/Femspd/Ftx008  0.364
2016 Yacovone SK, Smelser AM, Macosko JC, Holzwarth G, Ornelles DA, Lyles DS. Migration of Nucleocapsids in Vesicular Stomatitis Virus-Infected Cells is Dependent on Both Microtubules and Actin Filaments. Journal of Virology. PMID 27122580 DOI: 10.1128/Jvi.00488-16  0.446
2016 Ornelles DA, Gooding LR, Dickherber ML, Policard M, Garnett-Benson C. Limited but durable changes to cellular gene expression in a model of latent adenovirus infection are reflected in childhood leukemic cell lines Virology. 494: 67-77. DOI: 10.1016/J.Virol.2016.03.015  0.43
2015 Yacovone SK, Ornelles DA, Lyles DS. The border-to-border distribution method for analysis of cytoplasmic particles and organelles. Cell and Tissue Research. PMID 26310140 DOI: 10.1007/S00441-015-2265-X  0.343
2015 Ornelles DA, Gooding LR, Garnett-Benson C. Neonatal infection with species C adenoviruses confirmed in viable cord blood lymphocytes. Plos One. 10: e0119256. PMID 25764068 DOI: 10.1371/Journal.Pone.0119256  0.368
2015 Turner RL, Groitl P, Dobner T, Ornelles DA. Adenovirus replaces mitotic checkpoint controls. Journal of Virology. 89: 5083-96. PMID 25694601 DOI: 10.1128/Jvi.00213-15  0.72
2015 Murrah KA, Turner RL, Pang B, Perez AC, Reimche JL, King LB, Wren J, Gandhi U, Swords WE, Ornelles DA. Replication of type 5 adenovirus promotes middle ear infection by Streptococcus pneumoniae in the chinchilla model of otitis media. Pathogens and Disease. 73: 1-8. PMID 25251686 DOI: 10.1111/2049-632X.12216  0.626
2014 Turner RL, Wilkinson JC, Ornelles DA. E1B and E4 oncoproteins of adenovirus antagonize the effect of apoptosis inducing factor. Virology. 456: 205-19. PMID 24889240 DOI: 10.1016/J.Virol.2014.03.010  0.697
2014 Murali VK, Ornelles DA, Gooding LR, Wilms HT, Huang W, Tollefson AE, Wold WSM, Garnett-Benson C. Adenovirus Death Protein (ADP) is required for lytic infection of human lymphocytes Journal of Virology. 88: 903-912. PMID 24198418 DOI: 10.1128/Jvi.01675-13  0.523
2013 Furuse Y, Ornelles DA, Cullen BR. Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA. Virology. 447: 140-5. PMID 24210108 DOI: 10.1016/J.Virol.2013.08.024  0.389
2013 Gupta A, Jha S, Engel DA, Ornelles DA, Dutta A. Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA. Oncogene. 32: 5017-25. PMID 23178490 DOI: 10.1038/Onc.2012.534  0.506
2012 Kute T, Stehle Jr JR, Ornelles D, Walker N, Delbono O, Vaughn JP. Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells. Oncoimmunology. 1: 810-821. PMID 23162748 DOI: 10.4161/Onci.20447  0.307
2012 Murphy AM, Besmer DM, Moerdyk-Schauwecker M, Moestl N, Ornelles DA, Mukherjee P, Grdzelishvili VZ. Vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma. Journal of Virology. 86: 3073-87. PMID 22238308 DOI: 10.1128/Jvi.05640-11  0.385
2012 Kute TE, Stehle J, Ornelles D, Walker N, Vaughn J. Abstract 5374: Significance of ADCC for the action of trastuzumab quantified by novel procedures Cancer Research. 72: 5374-5374. DOI: 10.1158/1538-7445.Am2012-5374  0.325
2012 Murphy A, Besmer D, Moerdyk-Schauwecker M, Moestl N, Ornelles D, Mukherjee P, Grdzelishvili V. Abstract 2714: Vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma Cancer Research. 72: 2714-2714. DOI: 10.1158/1538-7445.Am2012-2714  0.441
2010 Zhang Y, Huang W, Ornelles DA, Gooding LR. Modeling adenovirus latency in human lymphocyte cell lines. Journal of Virology. 84: 8799-810. PMID 20573817 DOI: 10.1128/Jvi.00562-10  0.498
2009 Spurgeon ME, Ornelles DA. The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection. Journal of Virology. 83: 9970-82. PMID 19605483 DOI: 10.1128/Jvi.01113-09  0.764
2009 Nichols GJ, Schaack J, Ornelles DA. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. Journal of Virology. 83: 5987-98. PMID 19321613 DOI: 10.1128/Jvi.00091-09  0.491
2009 Thomas MA, Broughton RS, Goodrum FD, Ornelles DA. E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirus. Journal of Virology. 83: 2406-16. PMID 19129452 DOI: 10.1128/Jvi.01972-08  0.533
2009 Garnett CT, Talekar G, Mahr JA, Huang W, Zhang Y, Ornelles DA, Gooding LR. Latent species C adenoviruses in human tonsil tissues. Journal of Virology. 83: 2417-28. PMID 19109384 DOI: 10.1128/Jvi.02392-08  0.439
2008 Marshall LJ, Moore AC, Ohki M, Kitabayashi I, Patterson D, Ornelles DA. RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. Journal of Virology. 82: 6395-408. PMID 18417565 DOI: 10.1128/Jvi.00043-08  0.546
2007 Ornelles DA, Broughton-Shepard RN, Goodrum FD. Analysis of adenovirus infections in synchronized cells. Methods in Molecular Medicine. 131: 83-101. PMID 17656777 DOI: 10.1007/978-1-59745-277-9_7  0.474
2007 Hart LS, Ornelles D, Koumenis C. The adenoviral E4orf6 protein induces atypical apoptosis in response to DNA damage. The Journal of Biological Chemistry. 282: 6061-7. PMID 17172468 DOI: 10.1074/Jbc.M610405200  0.424
2006 Shapiro GS, Van Peursem C, Ornelles DA, Schaack J, DeGregori J. Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein. Journal of Virology. 80: 5349-60. PMID 16699015 DOI: 10.1128/Jvi.02016-05  0.443
2005 Weitzman MD, Ornelles DA. Inactivating intracellular antiviral responses during adenovirus infection. Oncogene. 24: 7686-96. PMID 16299529 DOI: 10.1038/Sj.Onc.1209063  0.504
2005 Stracker TH, Lee DV, Carson CT, Araujo FD, Ornelles DA, Weitzman MD. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. Journal of Virology. 79: 6664-73. PMID 15890904 DOI: 10.1128/Jvi.79.11.6664-6673.2005  0.451
2005 Xue Y, Johnson JS, Ornelles DA, Lieberman J, Engel DA. Adenovirus protein VII functions throughout early phase and interacts with cellular proteins SET and pp32. Journal of Virology. 79: 2474-83. PMID 15681448 DOI: 10.1128/Jvi.79.4.2474-2483.2005  0.546
2005 Hart LS, Yannone SM, Naczki C, Orlando JS, Waters SB, Akman SA, Chen DJ, Ornelles D, Koumenis C. The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner. The Journal of Biological Chemistry. 280: 1474-81. PMID 15507430 DOI: 10.1074/Jbc.M409934200  0.726
2004 Blanchette P, Cheng CY, Yan Q, Ketner G, Ornelles DA, Dobner T, Conaway RC, Conaway JW, Branton PE. Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Molecular and Cellular Biology. 24: 9619-29. PMID 15485928 DOI: 10.1128/Mcb.24.21.9619-9629.2004  0.434
2004 Shepard RN, Ornelles DA. Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background. Journal of Virology. 78: 9924-35. PMID 15331726 DOI: 10.1128/Jvi.78.18.9924-9935.2004  0.592
2004 McNees AL, Mahr JA, Ornelles D, Gooding LR. Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell lines. Journal of Virology. 78: 6955-66. PMID 15194772 DOI: 10.1128/Jvi.78.13.6955-6966.2004  0.455
2004 Schaack J, Bennett ML, Colbert JD, Torres AV, Clayton GH, Ornelles D, Moorhead J. E1A and E1B proteins inhibit inflammation induced by adenovirus. Proceedings of the National Academy of Sciences of the United States of America. 101: 3124-9. PMID 14976240 DOI: 10.1073/Pnas.0303709101  0.502
2003 Shepard RN, Ornelles DA. E4orf3 is necessary for enhanced S-phase replication of cell cycle-restricted subgroup C adenoviruses. Journal of Virology. 77: 8593-5. PMID 12857931 DOI: 10.1128/Jvi.77.15.8593-8595.2003  0.444
2003 Chastain-Moore AM, Roberts T, Trott DA, Newbold RF, Ornelles DA. An activity associated with human chromosome 21 permits nuclear colocalization of the adenovirus E1B-55K and E4orf6 proteins and promotes viral late gene expression. Journal of Virology. 77: 8087-98. PMID 12829847 DOI: 10.1128/Jvi.77.14.8087-8098.2003  0.518
2002 Orlando JS, Ornelles DA. E4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein. Journal of Virology. 76: 1475-87. PMID 11773420 DOI: 10.1128/Jvi.76.3.1475-1487.2002  0.734
1999 Goodrum FD, Ornelles DA. Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenovirus replication Journal of Virology. 73: 7474-7488. PMID 10438837 DOI: 10.1128/Jvi.73.9.7474-7488.1999  0.529
1999 Orlando JS, Ornelles DA. An arginine-faced amphipathic alpha helix is required for adenovirus type 5 e4orf6 protein function. Journal of Virology. 73: 4600-10. PMID 10233919 DOI: 10.1128/Jvi.73.6.4600-4610.1999  0.731
1998 Goodrum FD, Ornelles DA. p53 Status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection Journal of Virology. 72: 9479-9490. PMID 9811681 DOI: 10.1128/Jvi.72.12.9479-9490.1998  0.522
1997 Goodrum FD, Ornelles DA. The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle Journal of Virology. 71: 548-561. PMID 8985383 DOI: 10.1128/Jvi.71.1.548-561.1997  0.512
1996 Goodrum FD, Shenk T, Ornelles DA. Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells Journal of Virology. 70: 6323-6335. PMID 8709260 DOI: 10.1128/Jvi.70.9.6323-6335.1996  0.525
1995 Schaack J, Guo X, Ho WY, Karlok M, Chen C, Ornelles D. Adenovirus type 5 precursor terminal protein-expressing 293 and HeLa cell lines. Journal of Virology. 69: 4079-4085. DOI: 10.1128/Jvi.69.7.4079-4085.1995  0.507
1992 Hasson TB, Ornelles DA, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are present within assembling virions and colocalize with nuclear structures distinct from replication centers Journal of Virology. 66: 6133-6142. PMID 1527852 DOI: 10.1128/Jvi.66.10.6133-6142.1992  0.437
1991 Ornelles DA, Shenk T. Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: Association with nuclear viral inclusions requires the early region 4 34-kilodalton protein Journal of Virology. 65: 424-439. PMID 1824641  0.53
1990 Marton MJ, Baim SB, Ornelles DA, Shenk T. The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA Journal of Virology. 64: 2345-2359. PMID 2139141 DOI: 10.1128/Jvi.64.5.2345-2359.1990  0.312
1990 Ornelles DA, Penman S. Prompt heat-shock and heat-shifted proteins associated with the nuclear matrix-intermediate filament scaffold in Drosophila melanogaster cells. Journal of Cell Science. 95: 393-404. PMID 2117013  0.375
1989 Hasson TB, Soloway PD, Ornelles DA, Doerfler W, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions Journal of Virology. 63: 3612-3621. PMID 2760976 DOI: 10.1128/Jvi.63.9.3612-3621.1989  0.431
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