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Dai Stephens - Publications

University of Sussex, Falmer, England, United Kingdom 
behavioral neuroscience, alcohol and drug abuse

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dixon CI, Walker SE, Swinny J, Belelli D, Lambert JJ, King SL, Stephens DN. Early-life stress influences acute and sensitized responses of adult mice to cocaine by interacting with GABAA α2 receptor expression. Behavioural Pharmacology. PMID 30724801 DOI: 10.1097/Fbp.0000000000000466  0.96
2018 Mitchell SJ, Maguire EP, Cunningham L, Gunn BG, Linke M, Zechner U, Dixon CI, King SL, Stephens DN, Swinny JD, Belelli D, Lambert JJ. Early-life adversity selectively impairs α2-GABA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine. Neuropharmacology. PMID 30138693 DOI: 10.1016/J.Neuropharm.2018.08.021  0.96
2017 Kukalev A, Ng YM, Ju L, Saidi A, Lane S, Mondragon A, Dormann D, Walker SE, Grey W, Ho PW, Stephens DN, Carr AM, Lamsa K, Tse E, Yu VP. Deficiency of Cks1 Leads to Learning and Long-Term Memory Defects and p27 Dependent Formation of Neuronal Cofilin Aggregates. Cerebral Cortex (New York, N.Y. : 1991). 27: 11-23. PMID 28365778 DOI: 10.1093/cercor/bhw354  0.36
2017 Duka T, Nikolaou K, King SL, Banaschewski T, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Flor H, Gallinat J, Garavan H, Heinz A, Jia T, Gowland P, Martinot JL, ... ... Stephens DN, et al. GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents. Frontiers in Behavioral Neuroscience. 11: 24. PMID 28261068 DOI: 10.3389/Fnbeh.2017.00024  0.64
2016 Sanchez-Roige S, Stephens DN, Duka T. Heightened Impulsivity: Associated with Family History of Alcohol Misuse, and a Consequence of Alcohol Intake. Alcoholism, Clinical and Experimental Research. PMID 27565012 DOI: 10.1111/acer.13184  0.48
2016 Stephens DN, King SL, Lambert JJ, Belelli D, Duka T. GABAA Receptor Subtype Involvement in Addictive Behaviour. Genes, Brain, and Behavior. PMID 27539865 DOI: 10.1111/Gbb.12321  0.96
2016 Peña-Oliver Y, Carvalho FM, Sanchez-Roige S, Quinlan EB, Jia T, Walker-Tilley T, Rulten SL, Pearl FM, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod PJ, Flor H, Gallinat J, ... ... Stephens DN, et al. Mouse and Human Genetic Analyses Associate Kalirin with Ventral Striatal Activation during Impulsivity and with Alcohol Misuse. Frontiers in Genetics. 7: 52. PMID 27092175 DOI: 10.3389/Fgene.2016.00052  0.64
2015 Duka T, Dixon CI, Trick L, Crombag HS, King SL, Stephens DN. Motivational Effects of Methylphenidate are Associated with GABRA2 Variants Conferring Addiction Risk. Frontiers in Behavioral Neuroscience. 9: 304. PMID 26635556 DOI: 10.3389/Fnbeh.2015.00304  0.96
2015 Ripley TL, Sanchez-Roige S, Bullmore ET, Mugnaini M, Maltby K, Miller SR, Wille DR, Nathan P, Stephens DN. The novel mu-opioid antagonist, GSK1521498, reduces ethanol consumption in C57BL/6J mice. Psychopharmacology. PMID 26141191 DOI: 10.1007/s00213-015-3995-x  0.96
2015 Sanchez-Roige S, Ripley TL, Stephens DN. Alleviating waiting impulsivity and perseverative responding by μ-opioid receptor antagonism in two inbred mouse strains. Psychopharmacology. 232: 1483-92. PMID 25381183 DOI: 10.1007/s00213-014-3786-9  0.64
2014 Sanchez-Roige S, Peña-Oliver Y, Ripley TL, Stephens DN. Repeated ethanol exposure during early and late adolescence: double dissociation of effects on waiting and choice impulsivity. Alcoholism, Clinical and Experimental Research. 38: 2579-89. PMID 25346503 DOI: 10.1111/acer.12535  0.64
2014 Sanchez-Roige S, Baro V, Trick L, Peña-Oliver Y, Stephens DN, Duka T. Exaggerated waiting impulsivity associated with human binge drinking, and high alcohol consumption in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2919-27. PMID 24947901 DOI: 10.1038/npp.2014.151  0.64
2014 Dixon CI, Halbout B, King SL, Stephens DN. Deletion of the GABAA α2-subunit does not alter self administration of cocaine or reinstatement of cocaine seeking. Psychopharmacology. 231: 2695-703. PMID 24481569 DOI: 10.1007/S00213-014-3443-3  0.64
2014 Maguire EP, Macpherson T, Swinny JD, Dixon CI, Herd MB, Belelli D, Stephens DN, King SL, Lambert JJ. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 823-38. PMID 24431441 DOI: 10.1523/Jneurosci.3232-13.2014  0.64
2014 Peña-Oliver Y, Sanchez-Roige S, Stephens DN, Ripley TL. Alpha-synuclein deletion decreases motor impulsivity but does not affect risky decision making in a mouse Gambling Task. Psychopharmacology. 231: 2493-506. PMID 24402137 DOI: 10.1007/s00213-013-3416-y  0.64
2014 Weir RK, Dudley JA, Yan TC, Grabowska EM, Peña-Oliver Y, Ripley TL, Stephens DN, Stanford SC, Hunt SP. The influence of test experience and NK1 receptor antagonists on the performance of NK1R-/- and wild type mice in the 5-Choice Serial Reaction-Time Task. Journal of Psychopharmacology (Oxford, England). 28: 270-81. PMID 23845920 DOI: 10.1177/0269881113495722  0.64
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, ... ... Stephens DN, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/Ncomms3816  0.64
2013 Baldwin DS, Aitchison K, Bateson A, Curran HV, Davies S, Leonard B, Nutt DJ, Stephens DN, Wilson S. Benzodiazepines: risks and benefits. A reconsideration. Journal of Psychopharmacology (Oxford, England). 27: 967-71. PMID 24067791 DOI: 10.1177/0269881113503509  0.64
2013 Dudley JA, Weir RK, Yan TC, Grabowska EM, Grimmé AJ, Amini S, Stephens DN, Hunt SP, Stanford SC. Antagonism of L-type Ca(v) channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task. Neuropharmacology. 64: 329-36. PMID 22884624 DOI: 10.1016/J.Neuropharm.2012.06.056  0.64
2013 Stephens DN, Crombag HS, Duka T. The challenge of studying parallel behaviors in humans and animal models. Current Topics in Behavioral Neurosciences. 13: 611-45. PMID 21671191 DOI: 10.1007/7854_2011_133  0.96
2013 Macpherson T, Stephens D, King S. C.16 - Extrasynaptic Alpha4-Containing Gabaa Receptors Within The Nucleus Accumbens Produce Pathway-Specific Effects On Expression Of Cocaine-Induced Conditioned Place Preference Behavioural Pharmacology. 24. DOI: 10.1097/01.Fbp.0000434800.02419.2F  0.56
2012 Dixon CI, Walker SE, King SL, Stephens DN. Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration. Plos One. 7: e47135. PMID 23115637 DOI: 10.1371/Journal.Pone.0047135  0.64
2012 O'Daly OG, Trick L, Scaife J, Marshall J, Ball D, Phillips ML, Williams SS, Stephens DN, Duka T. Withdrawal-associated increases and decreases in functional neural connectivity associated with altered emotional regulation in alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2267-76. PMID 22617355 DOI: 10.1038/Npp.2012.77  0.64
2012 Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T, Barker GJ, Bellgrove MA, Büchel C, Byrne M, Cummins TD, Fauth-Bühler M, Flor H, Gallinat J, Heinz A, Ittermann B, ... ... Stephens DN, et al. Adolescent impulsivity phenotypes characterized by distinct brain networks. Nature Neuroscience. 15: 920-5. PMID 22544311 DOI: 10.1038/Nn.3092  0.64
2012 Peña-Oliver Y, Buchman VL, Dalley JW, Robbins TW, Schumann G, Ripley TL, King SL, Stephens DN. Deletion of alpha-synuclein decreases impulsivity in mice. Genes, Brain, and Behavior. 11: 137-46. PMID 22142176 DOI: 10.1111/j.1601-183X.2011.00758.x  0.64
2012 Sanchez-Roige S, Peña-Oliver Y, Stephens DN. Measuring impulsivity in mice: the five-choice serial reaction time task. Psychopharmacology. 219: 253-70. PMID 22089700 DOI: 10.1007/s00213-011-2560-5  0.64
2011 Duka T, Trick L, Nikolaou K, Gray MA, Kempton MJ, Williams H, Williams SC, Critchley HD, Stephens DN. Unique brain areas associated with abstinence control are damaged in multiply detoxified alcoholics. Biological Psychiatry. 70: 545-52. PMID 21612768 DOI: 10.1016/J.Biopsych.2011.04.006  0.96
2011 Walker SE, Peña-Oliver Y, Stephens DN. Learning not to be impulsive: disruption by experience of alcohol withdrawal. Psychopharmacology. 217: 433-42. PMID 21509502 DOI: 10.1007/s00213-011-2298-0  0.96
2011 Ripley TL, Stephens DN. Critical thoughts on current rodent models for evaluating potential treatments of alcohol addiction and withdrawal. British Journal of Pharmacology. 164: 1335-56. PMID 21470204 DOI: 10.1111/j.1476-5381.2011.01406.x  0.64
2011 Yan TC, Dudley JA, Weir RK, Grabowska EM, Peña-Oliver Y, Ripley TL, Hunt SP, Stephens DN, Stanford SC. Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day. Plos One. 6: e17586. PMID 21408181 DOI: 10.1371/Journal.Pone.0017586  0.96
2011 Duka T, Crombag HS, Stephens DN. Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkers. Journal of Psychopharmacology (Oxford, England). 25: 1235-55. PMID 21169391 DOI: 10.1177/0269881110388324  0.64
2011 Halbout B, Perreau-Lenz S, Dixon CI, Stephens DN, Spanagel R. Per1(Brdm1) mice self-administer cocaine and reinstate cocaine-seeking behaviour following extinction. Behavioural Pharmacology. 22: 76-80. PMID 21127416 DOI: 10.1097/Fbp.0B013E328341E9Ca  0.96
2010 Schumann G, Loth E, Banaschewski T, Barbot A, Barker G, Büchel C, Conrod PJ, Dalley JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Mallik C, ... ... Stephens DN, et al. The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology. Molecular Psychiatry. 15: 1128-39. PMID 21102431 DOI: 10.1038/Mp.2010.4  0.96
2010 O'Connor EC, Stephens DN, Crombag HS. Modeling appetitive Pavlovian-instrumental interactions in mice. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 8.25. PMID 20938924 DOI: 10.1002/0471142301.ns0825s53  0.96
2010 Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D. Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11973-82. PMID 20826661 DOI: 10.1523/Jneurosci.2550-10.2010  0.96
2010 O'Connor EC, Crombag HS, Mead AN, Stephens DN. The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1807-17. PMID 20375996 DOI: 10.1038/Npp.2010.48  0.96
2010 Stephens DN, Duka T, Crombag HS, Cunningham CL, Heilig M, Crabbe JC. Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. Addiction Biology. 15: 145-68. PMID 20148777 DOI: 10.1111/J.1369-1600.2009.00193.X  0.96
2010 Leeman RF, Heilig M, Cunningham CL, Stephens DN, Duka T, O'Malley SS. Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes. Addiction Biology. 15: 109-24. PMID 20148775 DOI: 10.1111/J.1369-1600.2009.00192.X  0.96
2010 Peña-Oliver Y, Buchman VL, Stephens DN. Lack of involvement of alpha-synuclein in unconditioned anxiety in mice. Behavioural Brain Research. 209: 234-40. PMID 20138921 DOI: 10.1016/j.bbr.2010.01.049  0.96
2010 Dixon CI, Morris HV, Breen G, Desrivieres S, Jugurnauth S, Steiner RC, Vallada H, Guindalini C, Laranjeira R, Messas G, Rosahl TW, Atack JR, Peden DR, Belelli D, Lambert JJ, ... ... Stephens DN, et al. Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 2289-94. PMID 20133874 DOI: 10.1073/Pnas.0910117107  0.96
2009 Morris HV, Nilsson S, Dixon CI, Stephens DN, Clifton PG. Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia. Appetite. 52: 675-83. PMID 19501766 DOI: 10.1016/J.Appet.2009.03.006  0.96
2009 Oliver YP, Ripley TL, Stephens DN. Ethanol effects on impulsivity in two mouse strains: similarities to diazepam and ketamine. Psychopharmacology. 204: 679-92. PMID 19263039 DOI: 10.1007/s00213-009-1500-0  0.96
2009 George SA, Hutson PH, Stephens DN. Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms. Psychopharmacology. 204: 499-509. PMID 19205667 DOI: 10.1007/S00213-009-1479-6  0.96
2008 Stephens DN, Duka T. Review. Cognitive and emotional consequences of binge drinking: role of amygdala and prefrontal cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3169-79. PMID 18640918 DOI: 10.1098/rstb.2008.0097  0.96
2008 Rulten SL, Hodder E, Ripley TL, Stephens DN, Mayne LV. Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain. Alcoholism, Clinical and Experimental Research. 32: 1186-96. PMID 18482162 DOI: 10.1111/j.1530-0277.2008.00673.x  0.96
2008 Morris HV, Dawson GR, Reynolds DS, Atack JR, Rosahl TW, Stephens DN. Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine. Pharmacology, Biochemistry, and Behavior. 90: 9-18. PMID 18358520 DOI: 10.1016/j.pbb.2008.02.010  0.96
2008 Dixon CI, Rosahl TW, Stephens DN. Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates. Pharmacology, Biochemistry, and Behavior. 90: 1-8. PMID 18313124 DOI: 10.1016/J.Pbb.2008.01.015  0.96
2007 Vlachou S, Nomikos GG, Stephens DN, Panagis G. Lack of evidence for appetitive effects of Delta 9-tetrahydrocannabinol in the intracranial self-stimulation and conditioned place preference procedures in rodents. Behavioural Pharmacology. 18: 311-9. PMID 17551324 DOI: 10.1097/FBP.0b013e3282186cf2  0.96
2007 Mead AN, Zamanillo D, Becker N, Stephens DN. AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 343-53. PMID 16495937 DOI: 10.1038/Sj.Npp.1301045  0.96
2006 Borlikova GG, Elbers NA, Stephens DN. Repeated withdrawal from ethanol spares contextual fear conditioning and spatial learning but impairs negative patterning and induces over-responding: evidence for effect on frontal cortical but not hippocampal function? The European Journal of Neuroscience. 24: 205-16. PMID 16882017 DOI: 10.1111/j.1460-9568.2006.04901.x  0.96
2006 Le Merrer J, Stephens DN. Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7163-71. PMID 16822973 DOI: 10.1523/JNEUROSCI.5345-05.2006  0.96
2006 Rulten SL, Ripley TL, Manerakis E, Stephens DN, Mayne LV. Ethanol modifies the effect of handling stress on gene expression: problems in the analysis of two-way gene expression studies in mouse brain. Brain Research. 1102: 39-43. PMID 16806122 DOI: 10.1016/j.brainres.2006.05.011  0.96
2006 Stephens DN. Animal models/tests of drug addiction: a quest for the holy grail, or the pursuit of wild geese? Addiction Biology. 11: 39-42. PMID 16759334 DOI: 10.1111/j.1369-1600.2006.00010.x  0.96
2006 Mead AN, Morris HV, Dixon CI, Rulten SL, Mayne LV, Zamanillo D, Stephens DN. AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice. Behavioral Neuroscience. 120: 241-8. PMID 16719688 DOI: 10.1037/0735-7044.120.2.241  0.96
2006 Morris HV, Dawson GR, Reynolds DS, Atack JR, Stephens DN. Both alpha2 and alpha3 GABAA receptor subtypes mediate the anxiolytic properties of benzodiazepine site ligands in the conditioned emotional response paradigm. The European Journal of Neuroscience. 23: 2495-504. PMID 16706856 DOI: 10.1111/j.1460-9568.2006.04775.x  0.96
2006 Collinson N, Atack JR, Laughton P, Dawson GR, Stephens DN. An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze. Psychopharmacology. 188: 619-28. PMID 16633803 DOI: 10.1007/s00213-006-0361-z  0.96
2006 Rulten SL, Ripley TL, Hunt CL, Stephens DN, Mayne LV. Sp1 and NFkappaB pathways are regulated in brain in response to acute and chronic ethanol. Genes, Brain, and Behavior. 5: 257-73. PMID 16594979 DOI: 10.1111/j.1601-183X.2005.00157.x  0.96
2006 Borlikova GG, Le Merrer J, Stephens DN. Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone. Psychopharmacology. 185: 188-200. PMID 16470400 DOI: 10.1007/s00213-005-0301-3  0.96
2005 Jackson A, Stephens D, Duka T. Gender differences in response to lorazepam in a human drug discrimination study Journal of Psychopharmacology. 19: 614-619. PMID 16272183 DOI: 10.1177/0269881105056659  0.96
2005 Stephens DN, Pistovcakova J, Worthing L, Atack JR, Dawson GR. Role of GABAA alpha5-containing receptors in ethanol reward: the effects of targeted gene deletion, and a selective inverse agonist. European Journal of Pharmacology. 526: 240-50. PMID 16253225 DOI: 10.1016/j.ejphar.2005.09.031  0.96
2005 Stephens DN, Ripley TL, Borlikova G, Schubert M, Albrecht D, Hogarth L, Duka T. Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus. Biological Psychiatry. 58: 392-400. PMID 16018978 DOI: 10.1016/J.Biopsych.2005.04.025  0.96
2005 Allison C, Pratt JA, Ripley TL, Stephens DN. alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate receptor autoradiography in mouse brain after single and repeated withdrawal from diazepam. The European Journal of Neuroscience. 21: 1045-56. PMID 15787709 DOI: 10.1111/J.1460-9568.2005.03902.X  0.96
2005 Little HJ, Stephens DN, Ripley TL, Borlikova G, Duka T, Schubert M, Albrecht D, Becker HC, Lopez MF, Weiss F, Drummond C, Peoples M, Cunningham C. Alcohol withdrawal and conditioning. Alcoholism, Clinical and Experimental Research. 29: 453-64. PMID 15770122 DOI: 10.1097/01.Alc.0000156737.56425.E3  0.96
2005 Mead AN, Brown G, Le Merrer J, Stephens DN. Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice. Psychopharmacology. 179: 164-71. PMID 15619119 DOI: 10.1007/S00213-004-2071-8  0.96
2005 Stephens DN. Glutamatergic systems and anxiety Dopamine and Glutamate in Psychiatric Disorders. 267-289. DOI: 10.1007/978-1-59259-852-6_12  0.64
2004 Stephens DN, Mead AN. Behavioural plasticity-induced changes in drug response. Commentary on Badiani and Robinson drug-induced neurobehavioral plasticity: the role of environmental context. Behavioural Pharmacology. 15: 377-80. PMID 15343063 DOI: 10.1097/00008877-200409000-00011  0.96
2004 Duka T, Gentry J, Malcolm R, Ripley TL, Borlikova G, Stephens DN, Veatch LM, Becker HC, Crews FT. Consequences of multiple withdrawals from alcohol. Alcoholism, Clinical and Experimental Research. 28: 233-46. PMID 15112931 DOI: 10.1097/01.Alc.0000113780.41701.81  0.96
2004 Horwood JM, Ripley TL, Stephens DN. Evidence for disrupted NMDA receptor function in tissue plasminogen activator knockout mice. Behavioural Brain Research. 150: 127-38. PMID 15033286 DOI: 10.1016/S0166-4328(03)00248-1  0.96
2004 Ripley TL, Borlikova G, Lyons S, Stephens DN. Selective deficits in appetitive conditioning as a consequence of ethanol withdrawal. The European Journal of Neuroscience. 19: 415-25. PMID 14725636 DOI: 10.1111/j.0953-816X.2003.03114.x  0.96
2003 Duka T, Townshend JM, Collier K, Stephens DN. Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients. Alcoholism, Clinical and Experimental Research. 27: 1563-72. PMID 14574226 DOI: 10.1097/01.ALC.0000090142.11260.D7  0.96
2003 Mead AN, Stephens DN. Involvement of AMPA receptor GluR2 subunits in stimulus-reward learning: evidence from glutamate receptor gria2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9500-7. PMID 14573529 DOI: 10.1523/Jneurosci.23-29-09500.2003  0.96
2003 Jackson A, Duka T, Stephens DN. Effects of alcohol and lorazepam during extinction of alcohol self-administration in rats. Journal of Psychopharmacology (Oxford, England). 17: 293-9. PMID 14513921 DOI: 10.1177/02698811030173011  0.96
2003 Kong WM, Stanley S, Gardiner J, Abbott C, Murphy K, Seth A, Connoley I, Ghatei M, Stephens D, Bloom S. A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1688-1690. PMID 12958177  0.96
2003 Ripley TL, O'Shea M, Stephens DN. Repeated withdrawal from ethanol impairs acquisition but not expression of conditioned fear. The European Journal of Neuroscience. 18: 441-8. PMID 12887426 DOI: 10.1046/j.1460-9568.2003.02759.x  0.96
2003 Ripley TL, Brown G, Dunworth SJ, Stephens DN. Aversive conditioning following repeated withdrawal from ethanol and epileptic kindling. The European Journal of Neuroscience. 17: 1664-70. PMID 12752384 DOI: 10.1046/j.1460-9568.2003.02604.x  0.96
2003 Stephens DN, Mead AN. What role do GluR1 subunits play in drug abuse? Trends in Neurosciences. 26: 181-2; author reply . PMID 12689767 DOI: 10.1016/S0166-2236(03)00080-8  0.96
2003 Mead AN, Stephens DN. Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1041-8. PMID 12574434 DOI: 10.1523/Jneurosci.23-03-01041.2003  0.96
2003 Jackson A, Stephens DN, Duka T. Lorazepam substitutes for the alcohol stimulus in social drinkers. Psychopharmacology. 166: 181-7. PMID 12529807 DOI: 10.1007/s00213-002-1294-9  0.96
2003 Yang Z, Stephens D, Dawson KJ, Drummond A, Nicholls G, Griffiths RC, Wilkinson-Herbots HM, Beaumont MA, Baird SJE, Lascoux M, Leblois R, Estoup A, Nielsen R, Hey J, Stumpf MPH. Discussion on the paper by Wilson, Weale and Balding Journal of the Royal Statistical Society. Series a: Statistics in Society. 166: 188-201. DOI: 10.1111/1467-985X.00265  0.96
2002 Ripley TL, Gadd CA, De Felipe C, Hunt SP, Stephens DN. Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors. Neuropharmacology. 43: 1258-68. PMID 12527475 DOI: 10.1016/S0028-3908(02)00295-2  0.96
2002 Stephens DN, Mead AN, Ripley TL. Studying the neurobiology of stimulant and alcohol abuse and dependence in genetically manipulated mice. Behavioural Pharmacology. 13: 327-45. PMID 12394407 DOI: 10.1097/00008877-200209000-00004  0.96
2002 Ripley TL, Dunworth SJ, Stephens DN. Consequences of amygdala kindling and repeated withdrawal from ethanol on amphetamine-induced behaviours. The European Journal of Neuroscience. 16: 1129-38. PMID 12383242 DOI: 10.1046/j.1460-9568.2002.02175.x  0.96
2002 Ripley TL, Dunworth SJ, Stephens DN. Effect of CGP39551 administration on the kindling of ethanol-withdrawal seizures. Psychopharmacology. 163: 157-65. PMID 12202962 DOI: 10.1007/s00213-002-1138-7  0.96
2002 Duka T, Townshend JM, Collier K, Stephens DN. Kindling of withdrawal: a study of craving and anxiety after multiple detoxifications in alcoholic inpatients. Alcoholism, Clinical and Experimental Research. 26: 785-95. PMID 12068246 DOI: 10.1097/00000374-200206000-00007  0.96
2002 Brown G, Stephens DN. Effects of cocaine on responding for ethanol or sucrose under a progressive ratio schedule. Behavioural Pharmacology. 13: 157-62. PMID 11981228  0.96
2002 Dunworth SJ, Stephens DN. Provision of cues to signal a withdrawal US prevents the US pre-exposure effect in a diazepam-withdrawal conditioned taste aversion. Psychopharmacology. 160: 245-52. PMID 11889493 DOI: 10.1007/s00213-001-0982-1  0.96
2001 Stephens DN, Brown G, Duka T, Ripley TL. Impaired fear conditioning but enhanced seizure sensitivity in rats given repeated experience of withdrawal from alcohol. The European Journal of Neuroscience. 14: 2023-31. PMID 11860497 DOI: 10.1046/j.0953-816X.2001.01824.x  0.96
2001 Horwood JM, Ripley TL, Stephens DN. DRL performance in mice with deletion of tPA, uPA or PAI-1 genes. Behavioural Pharmacology. 12: 487-96. PMID 11742143  0.96
2001 Ripley TL, Horwood JM, Stephens DN. Evidence for impairment of behavioural inhibition in performance of operant tasks in tPA-/- mice. Behavioural Brain Research. 125: 215-27. PMID 11682113 DOI: 10.1016/S0166-4328(01)00303-5  0.96
2001 Jackson A, Stephens DN, Duka T. A low dose alcohol drug discrimination in social drinkers: relationship with subjective effects. Psychopharmacology. 157: 411-20. PMID 11605101 DOI: 10.1007/s002130100817  0.96
2000 Bergman J, France CP, Holtzman SG, Katz JL, Koek W, Stephens DN. Agonist efficacy, drug dependence, and medications development: preclinical evaluation of opioid, dopaminergic, and GABAA-ergic ligands. Psychopharmacology. 153: 67-84. PMID 11255930 DOI: 10.1007/S002130000567  0.96
2000 Stephens DN, Dunworth SJ. Previous experience of diazepam withdrawal prevents the formation of a withdrawal-conditioned taste aversion: test of a blocking hypothesis. Behavioural Pharmacology. 11: 471-81. PMID 11103913  0.96
2000 Jackson A, Mead AN, Stephens DN. Behavioural effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-receptor antagonists and their relevance to substance abuse. Pharmacology & Therapeutics. 88: 59-76. PMID 11033384 DOI: 10.1016/S0163-7258(00)00078-4  0.96
2000 Stephens DN, Elliman TD, Dunworth SJ. State-dependent behavioural sensitization: evidence from a chlordiazepoxide state. Behavioural Pharmacology. 11: 161-7. PMID 10877121  0.96
2000 Dunworth SJ, Mead AN, Stephens DN. Previous experience of withdrawal from chronic diazepam ameliorates the aversiveness of precipitated withdrawal and reduces withdrawal-induced c-fos expression in nucleus accumbens. The European Journal of Neuroscience. 12: 1501-8. PMID 10762378 DOI: 10.1046/J.1460-9568.2000.00036.X  0.96
1999 Smith JW, Watson WP, Stephens DN, Little HJ. The calcium channel antagonist, nimodipine, decreases operant self-administration of low concentrations of ethanol. Behavioural Pharmacology. 10: 793-802. PMID 10780295  0.96
1999 Stephens DN, Brown G. Disruption of operant oral self-administration of ethanol, sucrose, and saccharin by the AMPA/kainate antagonist, NBQX, but not the AMPA antagonist, GYKI 52466. Alcoholism, Clinical and Experimental Research. 23: 1914-20. PMID 10630610  0.96
1999 Mead AN, Vasilaki A, Spyraki C, Duka T, Stephens DN. AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward. The European Journal of Neuroscience. 11: 4089-98. PMID 10583497 DOI: 10.1046/J.1460-9568.1999.00828.X  0.96
1999 Wisden W, Stephens DN. Towards better benzodiazepines. Nature. 401: 751-2. PMID 10548094 DOI: 10.1038/44482  0.96
1999 Duka T, Jackson A, Smith DC, Stephens DN. Relationship of components of an alcohol interoceptive stimulus to induction of desire for alcohol in social drinkers. Pharmacology, Biochemistry, and Behavior. 64: 301-9. PMID 10515306 DOI: 10.1016/S0091-3057(99)00080-5  0.96
1999 Mead AN, Stephens DN. CNQX but not NBQX prevents expression of amphetamine-induced place preference conditioning: a role for the glycine site of the NMDA receptor, but not AMPA receptors. The Journal of Pharmacology and Experimental Therapeutics. 290: 9-15. PMID 10381753  0.96
1999 Ripley TL, Rocha BA, Oglesby MW, Stephens DN. Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice. Brain Research. 826: 117-27. PMID 10216203 DOI: 10.1016/S0006-8993(99)01280-9  0.96
1998 Brown G, Jackson A, Stephens DN. Effects of repeated withdrawal from chronic ethanol on oral self-administration of ethanol on a progressive ratio schedule. Behavioural Pharmacology. 9: 149-61. PMID 10065934  0.96
1998 Duka T, Tasker R, Stephens DN. Alcohol choice and outcome expectancies in social drinkers. Behavioural Pharmacology. 9: 643-53. PMID 9862089  0.96
1998 Mead AN, Stephens DN. AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice. Neuropharmacology. 37: 1131-8. PMID 9833643 DOI: 10.1016/S0028-3908(98)00101-4  0.96
1998 Duka T, Tasker R, Russell K, Stephens DN. Discriminative stimulus properties of nicotine at low doses: the effects of caffeine preload. Behavioural Pharmacology. 9: 219-29. PMID 9832936  0.96
1998 Jackson A, Mead AN, Rocha BA, Stephens DN. AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice. Behavioural Pharmacology. 9: 457-67. PMID 9832931 DOI: 10.1097/00008877-199809000-00009  0.96
1998 Duka T, Stephens DN, Russell C, Tasker R. Discriminative stimulus properties of low doses of ethanol in humans. Psychopharmacology. 136: 379-89. PMID 9600584 DOI: 10.1007/s002130050581  0.96
1998 Dunworth SJ, Stephens DN. Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist. Psychopharmacology. 136: 308-10. PMID 9566818 DOI: 10.1007/s002130050571  0.96
1998 Ward BO, Stephens DN. Sensitisation of withdrawal signs following repeated withdrawal from a benzodiazepine: differences between measures of anxiety and seizure sensitivity. Psychopharmacology. 135: 342-52. PMID 9539258 DOI: 10.1007/s002130050521  0.96
1998 Galici R, Pinna G, Stephens DN, Schneider HH, Turski L. Tolerance to and dependence on alprazolam are due to changes in GABA(A) receptor function and are independent of exposure to experimental set-up Restorative Neurology and Neuroscience. 12: 233-237.  0.96
1997 Pinna G, Galici R, Schneider HH, Stephens DN, Turski L. Alprazolam dependence prevented by substituting with the beta-carboline abecarnil. Proceedings of the National Academy of Sciences of the United States of America. 94: 2719-23. PMID 9122263 DOI: 10.1073/pnas.94.6.2719  0.96
1997 Stephens DN. Animal models of anxiety; grounds for depression? Commentary on Rodgers, 'Animal models of anxiety: Where next?' Behavioural Pharmacology. 8: 497-501.  0.96
1996 Jackson A, Brown G, Stephens DN. N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4- isoxazoleproprionate (AMPA) glutamate-receptor antagonists have different interactions with the discriminative stimuli of abused drugs. Psychopharmacology. 128: 320-7. PMID 8972552 DOI: 10.1007/s002130050140  0.96
1996 Stephens DN, Cole BJ. AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks. Psychopharmacology. 126: 249-59. PMID 8876025 DOI: 10.1007/BF02246455  0.96
1996 Rex A, Stephens DN, Fink H. "Anxiolytic" action of diazepam and abecarnil in a modified open field test. Pharmacology, Biochemistry, and Behavior. 53: 1005-11. PMID 8801571 DOI: 10.1016/0091-3057(95)02121-3  0.96
1995 Stephens DN. A glutamatergic hypothesis of drug dependence: extrapolations from benzodiazepine receptor ligands. Behavioural Pharmacology. 6: 425-446. PMID 11224351  0.96
1995 Lytle DA, Emmett-Oglesby MW, Stephens DN. Discriminative stimulus effects of midazolam and abecarnil in rats treated chronically with diazepam or abecarnil. Psychopharmacology. 121: 339-46. PMID 8584616 DOI: 10.1007/BF02246073  0.96
1995 Schneider HH, Yamaguchi M, Andrews JS, Stephens DN. Discriminative stimulus properties of the stereoisomers of the phosphodiesterase inhibitor rolipram. Pharmacology, Biochemistry, and Behavior. 50: 211-7. PMID 7740060 DOI: 10.1016/0091-3057(94)00296-U  0.96
1995 Vorobjev VS, Sharonova IN, Skrebitsky VG, Schneider HH, Stephens DN. Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells. Neuropharmacology. 34: 157-63. PMID 7617141 DOI: 10.1016/0028-3908(94)00139-J  0.96
1995 O'Donnell M, Shapo BM, Eberle MJ, Stephens DN. Experimental studies on an efficient catheter array imaging system. Ultrasonic Imaging. 17: 83-94. PMID 7571209 DOI: 10.1177/016173469501700201  0.96
1994 Andrews JS, Grützner M, Stephens DN. The effects of ibotenic acid lesions of the basal forebrain on visual discrimination performance in rats. Brain Research Bulletin. 34: 407-12. PMID 8082033 DOI: 10.1016/0361-9230(94)90037-X  0.96
1994 Jones GH, Schneider C, Schneider HH, Seidler J, Cole BJ, Stephens DN. Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: an analysis based on fractional receptor occupancies. Psychopharmacology. 114: 191-9. PMID 7838907 DOI: 10.1007/BF02244836  0.96
1993 Stephens DN, Turski L. Kindling to the benzodiazepine receptor inverse agonist, FG 7142: evidence for involvement of NMDA, but not non-NMDA, glutamatergic receptors. Neuropharmacology. 32: 1011-7. PMID 8295711 DOI: 10.1016/0028-3908(93)90066-C  0.96
1993 Turski L, Stephens DN. Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam. The Journal of Pharmacology and Experimental Therapeutics. 267: 1215-20. PMID 8263782  0.96
1993 Steppuhn KG, Schneider HH, Turski L, Stephens DN. Long-term treatment with abecarnil does not induce diazepam-like dependence in mice. The Journal of Pharmacology and Experimental Therapeutics. 264: 1395-400. PMID 8095551  0.96
1993 Stephens DN, Turski L, Jones GH, Steppuhn KG, Schneider HH. Abecarnil: a novel anxiolytic with mixed full agonist/partial agonist properties in animal models of anxiety and sedation. Psychopharmacology Series. 11: 79-95. PMID 7908435  0.96
1993 Pribilla I, Neuhaus R, Huba R, Hillmann M, Turner JD, Stephens DN, Schneider HH. Abecarnil is a full agonist at some, and a partial agonist at other recombinant GABAA receptor subtypes. Psychopharmacology Series. 11: 50-61. PMID 7908433  0.96
1993 Cole BJ, Klewer M, Jones GH, Stephens DN. Contrasting effects of the competitive NMDA antagonist CPP and the non-competitive NMDA antagonist MK 801 on performance of an operant delayed matching to position task in rats. Psychopharmacology. 111: 465-71. PMID 7870988 DOI: 10.1007/BF02253537  0.96
1992 Turski L, Stephens DN. Excitatory amino acid antagonists protect mice against MPP+ seizures. Synapse (New York, N.Y.). 10: 120-5. PMID 1585255 DOI: 10.1002/syn.890100206  0.96
1992 Andrews JS, Grützner M, Stephens DN. Effects of cholinergic and non-cholinergic drugs on visual discrimination and delayed visual discrimination performance in rats. Psychopharmacology. 106: 523-30. PMID 1579625 DOI: 10.1007/BF02244825  0.96
1992 Clusmann H, Stabel J, Stephens DN, Heinemann U. Alterations in medial perforant path and mossy fiber induced field potentials in amygdala and beta-carboline (FG 7142) kindled rats. Neuroscience Letters. 146: 65-8. PMID 1475051 DOI: 10.1016/0304-3940(92)90173-5  0.96
1992 Coenen AM, Stephens DN, Van Luijtelaar EL. Effects of the beta-carboline abecarnil on epileptic activity, EEG, sleep and behavior of rats. Pharmacology, Biochemistry, and Behavior. 42: 401-5. PMID 1409773 DOI: 10.1016/0091-3057(92)90132-Y  0.96
1992 Turski L, Jacobsen P, Honoré T, Stephens DN. Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. The Journal of Pharmacology and Experimental Therapeutics. 260: 742-7. PMID 1371159  0.96
1992 Stephens DN, Turski L, Hillman M, Turner JD, Schneider HH, Yamaguchi M. What are the differences between abecarnil and conventional benzodiazepine anxiolytics? Advances in Biochemical Psychopharmacology. 47: 395-405. PMID 1354919  0.96
1990 Turski L, Niemann W, Stephens DN. Differential effects of antiepileptic drugs and beta-carbolines on seizures induced by excitatory amino acids. Neuroscience. 39: 799-807. PMID 2097526 DOI: 10.1016/0306-4522(90)90262-3  0.96
1990 Andrews JS, Stephens DN. Drug discrimination models in anxiety and depression. Pharmacology & Therapeutics. 47: 267-80. PMID 1975445 DOI: 10.1016/0163-7258(90)90090-O  0.96
1990 Turski L, Bressler K, Klockgether T, Stephens DN. Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice. Neuroscience Letters. 113: 66-71. PMID 1973274 DOI: 10.1016/0304-3940(90)90496-V  0.96
1990 Turski L, Stephens DN, Jensen LH, Petersen EN, Meldrum BS, Patel S, Hansen JB, Löscher W, Schneider HH, Schmiechen R. Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio. The Journal of Pharmacology and Experimental Therapeutics. 253: 344-52. PMID 1970362  0.96
1990 Stephens D. Qualitative factors in education, research and development: A position paper International Journal of Educational Development. 10: 143-149. DOI: 10.1016/0738-0593(90)90030-R  0.96
1989 Stephens DN, Turski LA, Turner JD, Schneider HH. Are changes in glutamatergic mechanisms responsible for kindling to the benzodiazepine receptor inverse agonist, FG 7142? British Journal of Pharmacology. 98: 837P. PMID 2558769  0.96
1989 Zimmermann LN, Schneider HH, Stephens DN. Binding characteristics reveal partial GABA agonist activities of SR 95531. Journal of Protein Chemistry. 8: 355-6. PMID 2551316 DOI: 10.1007/BF01674276  0.96
1989 Zimmermann LN, Schneider HH, Stephens DN. Partial GABA agonist activity of SR 95531 on the binding of [35S]TBPS, [3H]DMCM and [3H]lormetazepam to rat brain membranes. Biochemical Pharmacology. 38: 2889-93. PMID 2550012 DOI: 10.1016/0006-2952(89)90446-2  0.96
1989 Stephens DN, Weidmann R. Blockade of FG 7142 kindling by anticonvulsants acting at sites distant from the benzodiazepine receptor. Brain Research. 492: 89-98. PMID 2546658 DOI: 10.1016/0006-8993(89)90892-5  0.96
1989 Sarter M, Stephens DN. Disinhibitory properties of beta-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia? Biochemical Society Transactions. 17: 81-3. PMID 2541035  0.96
1989 Hodgson JM, Graham SP, Savakus AD, Dame SG, Stephens DN, Dhillon PS, Brands D, Sheehan H, Eberle MJ. Clinical percutaneous imaging of coronary anatomy using an over-the-wire ultrasound catheter system. International Journal of Cardiac Imaging. 4: 187-93. PMID 2527918 DOI: 10.1007/BF01745149  0.96
1988 Sarter M, Stephens DN. Beta-carbolines as tools in memory research: animal data and speculations. Psychopharmacology Series. 6: 230-45. PMID 3064084  0.96
1988 Stephens DN, Sarter M, Duka T, Dorow R, Schneider HH. [New approaches in memory research. The beta-carboline substance class]. Fortschritte Der Medizin. 106: 675-6, 677. PMID 3061909  0.96
1988 Stephens DN, Sarter M. Bidirectional nature of benzodiazepine receptor ligands extends to effects on vigilance. Psychopharmacology Series. 6: 205-17. PMID 2851141  0.96
1988 Löscher W, Stephens DN. Chronic treatment with diazepam or the inverse benzodiazepine receptor agonist FG 7142 causes differential changes in the effects of GABA receptor stimulation. Epilepsy Research. 2: 253-9. PMID 2848700 DOI: 10.1016/0920-1211(88)90016-2  0.96
1988 Schneider HH, Stephens DN. Co-existence of kindling induced by the beta-carboline, FG 7142, and tolerance to diazepam following chronic treatment in mice. European Journal of Pharmacology. 154: 35-45. PMID 2846325 DOI: 10.1016/0014-2999(88)90360-3  0.96
1988 Sarter M, Bodewitz G, Stephens DN. Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines. Psychopharmacology. 94: 491-5. PMID 2836875 DOI: 10.1007/BF00212843  0.96
1988 Sarter M, Schneider HH, Stephens DN. Treatment strategies for senile dementia: antagonist beta-carbolines. Trends in Neurosciences. 11: 13-7. PMID 2469147 DOI: 10.1016/0166-2236(88)90042-2  0.96
1988 Stephens DN, Schneider HH, Weidmann R, Zimmermann L. Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms. Advances in Biochemical Psychopharmacology. 45: 337-54. PMID 2459923  0.96
1988 Sarter M, Schneider HH, Stephens DN. Reply from Sarter and colleagues Trends in Neurosciences. 11: 211-212. DOI: 10.1016/0166-2236(88)90127-0  0.96
1987 Jensen LH, Stephens DN, Sarter M, Petersen EN. Bidirectional effects of beta-carbolines and benzodiazepines on cognitive processes. Brain Research Bulletin. 19: 359-64. PMID 3676858 DOI: 10.1016/0361-9230(87)90104-3  0.96
1987 Duka T, Stephens DN, Krause W, Dorow R. Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93,426: preliminary observations on psychotropic activity. Psychopharmacology. 93: 421-7. PMID 2829267 DOI: 10.1007/BF00207229  0.96
1987 Stephens DN, Schneider HH, Kehr W, Jensen LH, Petersen E, Honore T. Modulation of anxiety by beta-carbolines and other benzodiazepine receptor ligands: relationship of pharmacological to biochemical measures of efficacy. Brain Research Bulletin. 19: 309-18. PMID 2824003 DOI: 10.1016/0361-9230(87)90099-2  0.96
1986 Duka T, Stephens DN. Potentiation of the propunishment, but not the convulsant action of the beta-carboline DMCM by naltrexone. Pharmacology, Biochemistry, and Behavior. 25: 595-8. PMID 3022308 DOI: 10.1016/0091-3057(86)90147-4  0.96
1986 Herberg LJ, Montgomery AM, File SE, Pellow S, Stephens DN. Effect on hypothalamic self-stimulation of the novel beta-carbolines ZK 93 426 (a benzodiazepine receptor antagonist) and ZK 91 296 (a putative partial agonist). Journal of Neural Transmission. 66: 75-84. PMID 3018143 DOI: 10.1007/BF01260903  0.96
1986 Stephens DN, Meldrum BS, Weidmann R, Schneider C, Grützner M. Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity? Psychopharmacology. 90: 166-9. PMID 2878456 DOI: 10.1007/BF00181234  0.96
1986 Stephens DN, Kehr W, Duka T. Anxiolytic and anxiogenic beta-carbolines: tools for the study of anxiety mechanisms. Advances in Biochemical Psychopharmacology. 41: 91-106. PMID 2874697  0.96
1985 Stephens DN, Weidmann R, Quartermain D, Sarter M. Reversal learning in senescent rats. Behavioural Brain Research. 17: 193-202. PMID 4084391 DOI: 10.1016/0166-4328(85)90043-9  0.96
1985 Stephens DN, Schneider HH. Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity. Psychopharmacology. 87: 322-7. PMID 3001806 DOI: 10.1007/BF00432715  0.96
1985 Stephens DN, Kehr W. Beta-carbolines can enhance or antagonize the effects of punishment in mice. Psychopharmacology. 85: 143-7. PMID 2861616 DOI: 10.1007/BF00428403  0.96
1985 Stephens DN, Kehr W, Wachtel H, Schmiechen R. The anxiolytic activity of beta-carboline derivatives in mice, and its separation from ataxic properties. Pharmacopsychiatry. 18: 167-70. PMID 2859620 DOI: 10.1055/s-2007-1017357  0.96
1984 Smart JL, Stephens DN, Tonkiss J, Auestad NS, Edmond J. Growth and development of rats artificially reared on different milk-substitutes. The British Journal of Nutrition. 52: 227-37. PMID 6477861 DOI: 10.1079/BJN19840091  0.64
1984 Jensen LH, Petersen EN, Braestrup C, Honoré T, Kehr W, Stephens DN, Schneider H, Seidelmann D, Schmiechen R. Evaluation of the beta-carboline ZK 93 426 as a benzodiazepine receptor antagonist. Psychopharmacology. 83: 249-56. PMID 6089247 DOI: 10.1007/BF00464789  0.96
1984 Petersen EN, Jensen LH, Honoré T, Braestrup C, Kehr W, Stephens DN, Wachtel H, Seidelman D, Schmiechen R. ZK 91296, a partial agonist at benzodiazepine receptors. Psychopharmacology. 83: 240-8. PMID 6089246 DOI: 10.1007/BF00464788  0.96
1984 Stephens DN, Shearman GT, Kehr W. Discriminative stimulus properties of beta-carbolines characterized as agonists and inverse agonists at central benzodiazepine receptors. Psychopharmacology. 83: 233-9. PMID 6089245 DOI: 10.1007/BF00464787  0.96
1984 Stephens DN, Kehr W, Schneider HH, Schmiechen R. Beta-carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat. Neuroscience Letters. 47: 333-8. PMID 6089053 DOI: 10.1016/0304-3940(84)90535-4  0.96
1983 Smart JL, Stephens DN, Katz HB. Growth and development of rats artificially reared on a high or a low plane of nutrition. The British Journal of Nutrition. 49: 497-506. PMID 6860628 DOI: 10.1079/BJN19830058  0.64
1982 Rothwell NJ, Stephens DN, Stock MJ. Changes in metabolic rate and brown adipose tissue composition during nutritional rehabilitation of postnatally undernourished rats. Biology of the Neonate. 42: 93-9. PMID 7126717 DOI: 10.1159/000241581  0.64
1982 Latham A, Paul DH, Smart JL, Stephens DN. Comparison of cerebellar Purkinje cell simple spike discharges in adult rats after undernutrition during the suckling period and nutritionally normal rats. Brain Research. 256: 223-7. PMID 7104754 DOI: 10.1016/0165-3806(82)90044-X  0.64
1982 Stephens DN, Tonkiss J, Wearden JH. Differences between rats and undernourished preweaning, and controls in learning about a redundant stimulus during acquisition of a conditioned emotional response. Physiology & Behavior. 28: 95-101. PMID 6804995 DOI: 10.1016/0031-9384(82)90109-3  0.64
1981 Stephens DN, Nash SC, Proffitt C. Dietary obesity in adult and weanling rats following removal of interscapular brown adipose tissue. Pflã¼Gers Archiv : European Journal of Physiology. 392: 7-12. PMID 7322835 DOI: 10.1007/BF00584574  0.64
1981 Stephens DN, Tonkiss J. Rats undernourished as infants differ from controls in learning about a compound but not a simple discriminative stimulus. Physiology & Behavior. 26: 803-8. PMID 7267773 DOI: 10.1016/0031-9384(81)90103-7  0.64
1980 Stephens DN. Growth and the development of dietary obesity in adulthood of rats which have been undernourished during development. The British Journal of Nutrition. 44: 215-27. PMID 7437405 DOI: 10.1079/BJN19800034  0.64
1980 Stephens DN. Does the Lee obesity index measure general obesity? Physiology & Behavior. 25: 313-5. PMID 7413839 DOI: 10.1016/0031-9384(80)90222-X  0.64
1979 Stephens DN, Herberg LJ. Dopamine--acetylcholine "balance" in nucleus accumbens and corpus striatum and its effect on hypothalamic self-stimulation. European Journal of Pharmacology. 54: 331-9. PMID 436932 DOI: 10.1016/0014-2999(79)90062-1  0.96
1977 Herberg LJ, Stephens DN. Interaction of hunger and thirst in the motivational arousal underlying hoarding behavior in the rat. Journal of Comparative and Physiological Psychology. 91: 359-64. PMID 870549  0.64
1977 Morrissey SM, Stephens DN, Webber DE. The role of the posterior hypothalamus in hypoglycaemia and gastric secretion [proceedings]. The Journal of Physiology. 266: 85P-86P. PMID 853438  0.64
1977 Stephens DN, Herberg LJ. Effects on hypothalamic self-stimulation of drugs influencing dopaminergic neurotransmission injected into nucleus accumbens and corpus striatum of rats. Psychopharmacology. 54: 81-5. PMID 198840 DOI: 10.1007/BF00426546  0.96
1976 Herberg LJ, Stephens DN. Cyclic AMP and central noradrenaline receptors: failure to activate diencephalic adrenergic feeding pathways. Pharmacology, Biochemistry, and Behavior. 4: 107-10. PMID 177997 DOI: 10.1016/0091-3057(76)90183-0  0.96
1976 Herberg LJ, Stephens DN, Franklin KB. Catecholamines and self-stimulation: evidence suggesting a reinforcing role for noradrenaline and a motivating role for dopamine. Pharmacology, Biochemistry, and Behavior. 4: 575-82. PMID 133356 DOI: 10.1016/0091-3057(76)90200-8  0.96
1975 Herberg LJ, Stephens DN. Catecholamines and self-stimulation: the action of amantadine and its interaction with amphetamine. Pharmacology, Biochemistry, and Behavior. 3: 263-9. PMID 1144482 DOI: 10.1016/0091-3057(75)90156-2  0.96
1975 Stephens DN, Herberg LJ. Catecholamines and self-stimulation: pharmacological differences between near- and far-lateral hypothalamic sites. Brain Research. 90: 348-51. PMID 1139312 DOI: 10.1016/0006-8993(75)90318-2  0.96
1975 Stephens DN, Morrissey SM. Hypothalamic stimulation induces acid secretion, hypoglycemia, and hyperinsulinemia. The American Journal of Physiology. 228: 1206-9. PMID 1130520  0.64
1975 Stephens DN, Herberg LJ. Letter: obesity and glucose receptors. Lancet. 1: 521. PMID 46987 DOI: 10.1016/S0140-6736(75)92864-0  0.64
1972 Morrissey S, Stephens DN. The role of the posterior hypothalamus in gastric acid secretion. The Journal of Physiology. 221: 14P-15P. PMID 5016978  0.64
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