John Flanagan - Publications

Harvard Medical School, Boston, MA, United States 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG. Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell. 184: 2520. PMID 33930296 DOI: 10.1016/j.cell.2021.04.018  0.773
2019 Koppers M, Cagnetta R, Shigeoka T, Wunderlich LC, Vallejo-Ramirez P, Qiaojin Lin J, Zhao S, Jakobs MA, Dwivedy A, Minett MS, Bellon A, Kaminski CF, Harris WA, Flanagan J, Holt CE. Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. Elife. 8. PMID 31746735 DOI: 10.7554/Elife.48718  0.796
2016 Preitner N, Quan J, Li X, Nielsen FC, Flanagan JG. IMP2 axonal localization, RNA interactome, and function in development of axon trajectories. Development (Cambridge, England). PMID 27385015 DOI: 10.1242/dev.128348  0.302
2014 Preitner N, Quan J, Nowakowski DW, Hancock ML, Shi J, Tcherkezian J, Young-Pearse TL, Flanagan JG. APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly. Cell. 158: 368-82. PMID 25036633 DOI: 10.1016/J.Cell.2014.05.042  0.79
2013 Preitner N, Quan J, Flanagan JG. This message will self-destruct: NMD regulates axon guidance. Cell. 153: 1185-7. PMID 23746834 DOI: 10.1016/j.cell.2013.05.019  0.31
2011 Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG. Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development (Cambridge, England). 138: 4887-98. PMID 22028026 DOI: 10.1242/Dev.072306  0.793
2011 Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, Lu W, Gallagher JT, Jones EY, Flanagan JG, Aricescu AR. Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (New York, N.Y.). 332: 484-8. PMID 21454754 DOI: 10.1126/Science.1200840  0.778
2010 Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG. Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell. 141: 632-44. PMID 20434207 DOI: 10.1016/J.Cell.2010.04.008  0.794
2009 Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J, Flanagan JG. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science (New York, N.Y.). 326: 592-6. PMID 19833921 DOI: 10.1126/Science.1178310  0.799
2009 Chen Y, Mohammadi M, Flanagan JG. Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels. Neuron. 62: 773-80. PMID 19555646 DOI: 10.1016/J.Neuron.2009.05.023  0.424
2009 Baba A, Akagi K, Takayanagi M, Flanagan JG, Kobayashi T, Hattori M. Fyn tyrosine kinase regulates the surface expression of glycosylphosphatidylinositol-linked ephrin via the modulation of sphingomyelin metabolism. The Journal of Biological Chemistry. 284: 9206-14. PMID 19181669 DOI: 10.1074/Jbc.M809401200  0.432
2008 Qiu R, Wang X, Davy A, Wu C, Murai K, Zhang H, Flanagan JG, Soriano P, Lu Q. Regulation of neural progenitor cell state by ephrin-B. The Journal of Cell Biology. 181: 973-83. PMID 18541704 DOI: 10.1083/Jcb.200708091  0.376
2008 Osterfield M, Egelund R, Young LM, Flanagan JG. Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. Development (Cambridge, England). 135: 1189-99. PMID 18272596 DOI: 10.1242/dev.007401  0.79
2006 Chen Y, Flanagan JG. Follow your nose: axon pathfinding in olfactory map formation. Cell. 127: 881-4. PMID 17129775 DOI: 10.1016/J.Cell.2006.11.017  0.483
2006 Johnson KG, Tenney AP, Ghose A, Duckworth AM, Higashi ME, Parfitt K, Marcu O, Heslip TR, Marsh JL, Schwarz TL, Flanagan JG, Van Vactor D. The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Neuron. 49: 517-31. PMID 16476662 DOI: 10.1016/J.Neuron.2006.01.026  0.764
2006 Flanagan JG. Neural map specification by gradients Current Opinion in Neurobiology. 16: 59-66. PMID 16417998 DOI: 10.1016/j.conb.2006.01.010  0.321
2005 Pfeiffenberger C, Cutforth T, Woods G, Yamada J, Rentería RC, Copenhagen DR, Flanagan JG, Feldheim DA. Ephrin-As and neural activity are required for eye-specific patterning during retinogeniculate mapping. Nature Neuroscience. 8: 1022-7. PMID 16025107 DOI: 10.1038/Nn1508  0.757
2005 Ellsworth CA, Lyckman AW, Feldheim DA, Flanagan JG, Sur M. Ephrin-A2 and -A5 influence patterning of normal and novel retinal projections to the thalamus: conserved mapping mechanisms in visual and auditory thalamic targets. The Journal of Comparative Neurology. 488: 140-51. PMID 15924339 DOI: 10.1002/cne.20602  0.69
2004 Kantor DB, Chivatakarn O, Peer KL, Oster SF, Inatani M, Hansen MJ, Flanagan JG, Yamaguchi Y, Sretavan DW, Giger RJ, Kolodkin AL. Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans. Neuron. 44: 961-75. PMID 15603739 DOI: 10.1016/J.Neuron.2004.12.002  0.586
2004 Lu Q, Sun EE, Flanagan JG. Analysis of PDZ-RGS3 function in ephrin-B reverse signaling. Methods in Enzymology. 390: 120-8. PMID 15488174 DOI: 10.1016/S0076-6879(04)90008-0  0.64
2004 Bach H, Arango V, Feldheim D, Flanagan JG, Scalia F. Fiber order of the normal and regenerated optic tract of the frog (Rana Pipiens) Journal of Comparative Neurology. 477: 43-54. PMID 15281079 DOI: 10.1002/cne.20238  0.686
2004 Hansen MJ, Dallal GE, Flanagan JG. Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibition. Neuron. 42: 717-30. PMID 15182713 DOI: 10.1016/J.Neuron.2004.05.009  0.543
2004 Feldheim DA, Nakamoto M, Osterfield M, Gale NW, DeChiara TM, Rohatgi R, Yancopoulos GD, Flanagan JG. Loss-of-function analysis of EphA receptors in retinotectal mapping. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2542-50. PMID 15014130 DOI: 10.1523/Jneurosci.0239-03.2004  0.797
2003 Bach H, Feldheim DA, Flanagan JG, Scalia F. Persistence of graded EphA/Ephrin-A expression in the adult frog visual system. The Journal of Comparative Neurology. 467: 549-65. PMID 14624488 DOI: 10.1002/cne.10941  0.685
2003 Dufour A, Seibt J, Passante L, Depaepe V, Ciossek T, Frisén J, Kullander K, Flanagan JG, Polleux F, Vanderhaeghen P. Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes. Neuron. 39: 453-65. PMID 12895420 DOI: 10.1016/S0896-6273(03)00440-9  0.655
2003 Osterfield M, Kirschner MW, Flanagan JG. Graded positional information: interpretation for both fate and guidance. Cell. 113: 425-8. PMID 12757702 DOI: 10.1016/S0092-8674(03)00359-3  0.779
2002 Nishida K, Flanagan JG, Nakamoto M. Domain-specific olivocerebellar projection regulated by the EphA-ephrin-A interaction. Development (Cambridge, England). 129: 5647-58. PMID 12421705 DOI: 10.1242/Dev.00162  0.559
2002 Brittis PA, Lu Q, Flanagan JG. Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell. 110: 223-35. PMID 12150930 DOI: 10.1016/S0092-8674(02)00813-9  0.808
2001 Lyckman AW, Jhaveri S, Feldheim DA, Vanderhaeghen P, Flanagan JG, Sur M. Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7684-90. PMID 11567058 DOI: 10.1523/Jneurosci.21-19-07684.2001  0.758
2001 Brittis PA, Flanagan JG. Nogo domains and a Nogo receptor: implications for axon regeneration. Neuron. 30: 11-4. PMID 11343640 DOI: 10.1016/S0896-6273(01)00258-6  0.774
2001 Lu Q, Sun EE, Klein RS, Flanagan JG. Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 105: 69-79. PMID 11301003 DOI: 10.1016/S0092-8674(01)00297-5  0.66
2001 Cheng HJ, Flanagan JG. Cloning and characterization of RTK ligands using receptor-alkaline phosphatase fusion proteins. Methods in Molecular Biology (Clifton, N.J.). 124: 313-34. PMID 11100484 DOI: 10.1385/1-59259-059-4:313  0.528
2000 Flanagan JG, Cheng HJ. Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligands. Methods in Enzymology. 327: 198-210. PMID 11044984 DOI: 10.1016/S0076-6879(00)27277-7  0.545
2000 Flanagan JG, Cheng HJ, Feldheim DA, Hattori M, Lu Q, Vanderhaeghen P. Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos. Methods in Enzymology. 327: 19-35. PMID 11044971 DOI: 10.1016/S0076-6879(00)27264-9  0.777
2000 Hattori M, Osterfield M, Flanagan JG. Regulated cleavage of a contact-mediated axon repellent. Science (New York, N.Y.). 289: 1360-5. PMID 10958785 DOI: 10.1126/Science.289.5483.1360  0.551
2000 Prakash N, Vanderhaeghen P, Cohen-Cory S, Frisén J, Flanagan JG, Frostig RD. Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5841-7. PMID 10908626 DOI: 10.1523/Jneurosci.20-15-05841.2000  0.582
2000 Feldheim DA, Kim YI, Bergemann AD, Frisén J, Barbacid M, Flanagan JG. Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. Neuron. 25: 563-74. PMID 10774725 DOI: 10.1016/S0896-6273(00)81060-0  0.674
2000 Vanderhaeghen P, Lu Q, Prakash N, Frisén J, Walsh CA, Frostig RD, Flanagan JG. A mapping label required for normal scale of body representation in the cortex. Nature Neuroscience. 3: 358-65. PMID 10725925 DOI: 10.1038/73929  0.671
2000 Feng G, Laskowski MB, Feldheim DA, Wang H, Lewis R, Frisen J, Flanagan JG, Sanes JR. Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers. Neuron. 25: 295-306. PMID 10719886 DOI: 10.1016/S0896-6273(00)80895-8  0.647
1998 Feldheim DA, Vanderhaeghen P, Hansen MJ, Frisén J, Lu Q, Barbacid M, Flanagan JG. Topographic guidance labels in a sensory projection to the forebrain. Neuron. 21: 1303-13. PMID 9883724 DOI: 10.1016/S0896-6273(00)80650-9  0.803
1998 Flanagan JG, Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annual Review of Neuroscience. 21: 309-45. PMID 9530499 DOI: 10.1146/annurev.neuro.21.1.309  0.678
1998 Bergemann AD, Zhang L, Chiang MK, Brambilla R, Klein R, Flanagan JG. Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16: 471-80. PMID 9484836 DOI: 10.1038/Sj.Onc.1201557  0.582
1998 Flanagan JG. Ephrins and their receptors as axon guidance labels in neural map development Faseb Journal. 12: A1291.  0.336
1997 Nakamoto M, Cheng H, Hansen MJ, Bergemann AD, Yoon CH, Friedman GC, McLaughlin T, O'Leary DD, Flanagan JG. S1-2 Eph receptors and their ligands in the development of retinotectal projection Neuroscience Research. 28: S3. DOI: 10.1016/S0168-0102(97)90003-1  0.701
1996 Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors Molecular and Cellular Neurosciences. 8: 199-209. PMID 8918835 DOI: 10.1006/Mcne.1996.0057  0.305
1996 Nakamoto M, Cheng HJ, Friedman GC, McLaughlin T, Hansen MJ, Yoon CH, O'Leary DD, Flanagan JG. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell. 86: 755-66. PMID 8797822 DOI: 10.1016/S0092-8674(00)80150-6  0.75
1996 Chiang MK, Flanagan JG. PTP-NP, a new member of the receptor protein tyrosine phosphatase family, implicated in development of nervous system and pancreatic endocrine cells. Development (Cambridge, England). 122: 2239-50. PMID 8681804  0.543
1996 Cao Y, Chen H, Zhou L, Chiang MK, Anand-Apte B, Weatherbee JA, Wang Y, Fang F, Flanagan JG, Tsang ML. Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. The Journal of Biological Chemistry. 271: 3154-62. PMID 8621715 DOI: 10.1074/Jbc.271.6.3154  0.498
1995 Chiang MK, Flanagan JG. Interactions between the Flk-1 receptor, vascular endothelial growth factor, and cell surface proteoglycan identified with a soluble receptor reagent. Growth Factors (Chur, Switzerland). 12: 1-10. PMID 8527158 DOI: 10.3109/08977199509003208  0.57
1995 Bergemann AD, Cheng HJ, Brambilla R, Klein R, Flanagan JG. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Molecular and Cellular Biology. 15: 4921-9. PMID 7651410 DOI: 10.1128/Mcb.15.9.4921  0.511
1995 Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 82: 371-81. PMID 7634327 DOI: 10.1016/0092-8674(95)90426-3  0.665
1994 Cheng HJ, Flanagan JG. Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membrane. Molecular Biology of the Cell. 5: 943-53. PMID 7531036 DOI: 10.1091/Mbc.5.9.943  0.484
1994 Cheng HJ, Flanagan JG. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell. 79: 157-68. PMID 7522971 DOI: 10.1016/0168-9525(95)90592-8  0.517
1992 Ornitz DM, Yayon A, Flanagan JG, Svahn CM, Levi E, Leder P. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Molecular and Cellular Biology. 12: 240-7. PMID 1309590 DOI: 10.1128/Mcb.12.1.240  0.491
1991 Flanagan JG, Chan DC, Leder P. Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell. 64: 1025-35. PMID 1705866 DOI: 10.1016/0092-8674(91)90326-T  0.464
1990 Flanagan JG, Leder P. The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell. 63: 185-94. PMID 1698555 DOI: 10.1016/0092-8674(90)90299-T  0.495
1988 Flanagan JG, Leder P. neu protooncogene fused to an immunoglobulin heavy chain gene requires immunoglobulin light chain for cell surface expression and oncogenic transformation. Proceedings of the National Academy of Sciences of the United States of America. 85: 8057-61. PMID 2903500 DOI: 10.1073/Pnas.85.21.8057  0.444
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