| Year |
Citation |
Score |
| 2024 |
Lam I, Ndayisaba A, Lewis AJ, Fu Y, Sagredo GT, Kuzkina A, Zaccagnini L, Celikag M, Sandoe J, Sanz RL, Vahdatshoar A, Martin TD, Morshed N, Ichihashi T, Tripathi A, ... ... Jaenisch R, et al. Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions. Neuron. PMID 39079530 DOI: 10.1016/j.neuron.2024.06.002 |
0.472 |
|
| 2024 |
Liu Y, Flamier A, Bell GW, Diao AJ, Whitfield TW, Wang HC, Wu Y, Schulte F, Friesen M, Guo R, Mitalipova M, Liu XS, Vos SM, Young RA, Jaenisch R. MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. Neuron. PMID 38697112 DOI: 10.1016/j.neuron.2024.04.007 |
0.456 |
|
| 2023 |
Lasry R, Maoz N, Cheng AW, Yom Tov N, Kulenkampff E, Azagury M, Yang H, Ople C, Markoulaki S, Faddah DA, Makedonski K, Orzech D, Sabag O, Jaenisch R, Buganim Y. Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects. Stem Cell Reports. PMID 37832543 DOI: 10.1016/j.stemcr.2023.09.009 |
0.391 |
|
| 2023 |
Qian J, Guan X, Xie B, Xu C, Niu J, Tang X, Li CH, Colecraft HM, Jaenisch R, Liu XS. Multiplex epigenome editing of to rescue Rett syndrome neurons. Science Translational Medicine. 15: eadd4666. PMID 36652535 DOI: 10.1126/scitranslmed.add4666 |
0.713 |
|
| 2022 |
Dall'Agnese A, Platt JM, Zheng MM, Friesen M, Dall'Agnese G, Blaise AM, Spinelli JB, Henninger JE, Tevonian EN, Hannett NM, Lazaris C, Drescher HK, Bartsch LM, Kilgore HR, Jaenisch R, et al. The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance. Nature Communications. 13: 7522. PMID 36473871 DOI: 10.1038/s41467-022-35176-7 |
0.321 |
|
| 2022 |
Ma H, Zwaan E, Guo YE, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, Fu D, Garrett-Engele C, Lee TI, Long HW, Griffith LG, ... ... Jaenisch R, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 29: 1611. PMID 36332573 DOI: 10.1016/j.stem.2022.10.003 |
0.382 |
|
| 2022 |
Ma H, de Zwaan E, Guo YE, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, Fu D, Garrett-Engele C, Lee TI, Long HW, Griffith LG, ... ... Jaenisch R, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. PMID 35452598 DOI: 10.1016/j.stem.2022.03.015 |
0.438 |
|
| 2021 |
Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Reply to Briggs et al.: Genomic integration and expression of SARS-CoV-2 sequences can explain prolonged or recurrent viral RNA detection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34702742 DOI: 10.1073/pnas.2114995118 |
0.34 |
|
| 2021 |
Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, ... ... Jaenisch R, et al. OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human. Nature Communications. 12: 5123. PMID 34446700 DOI: 10.1038/s41467-021-25107-3 |
0.301 |
|
| 2021 |
Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Response to Parry et al.: Strong evidence for genomic integration of SARS-CoV-2 sequences and expression in patient tissues. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34344760 DOI: 10.1073/pnas.2109497118 |
0.339 |
|
| 2021 |
Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33958444 DOI: 10.1073/pnas.2105968118 |
0.413 |
|
| 2021 |
Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, ... ... Jaenisch R, et al. Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases. Science Advances. 7. PMID 33514545 DOI: 10.1126/sciadv.abd1707 |
0.695 |
|
| 2020 |
Zhang L, Richards A, Khalil A, Wogram E, Ma H, Young RA, Jaenisch R. SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome. Biorxiv : the Preprint Server For Biology. PMID 33330870 DOI: 10.1101/2020.12.12.422516 |
0.413 |
|
| 2020 |
Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, ... ... Jaenisch R, et al. MeCP2 links heterochromatin condensates and neurodevelopmental disease. Nature. PMID 32698189 DOI: 10.1038/S41586-020-2574-4 |
0.509 |
|
| 2020 |
Murai N, Mitalipova M, Jaenisch R. Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell-derived microglia-like cells. The European Journal of Neuroscience. PMID 32579729 DOI: 10.1111/Ejn.14879 |
0.418 |
|
| 2020 |
Huang Q, Cohen MA, Alsina FC, Devlin G, Garrett A, McKey J, Havlik P, Rakhilin N, Wang E, Xiang K, Mathews P, Wang L, Bock C, Ruthig V, Wang Y, ... ... Jaenisch R, et al. Intravital imaging of mouse embryos. Science (New York, N.Y.). 368: 181-186. PMID 32273467 DOI: 10.1126/Science.Aba0210 |
0.621 |
|
| 2020 |
Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras. Cell Stem Cell. PMID 32142683 DOI: 10.1016/J.Stem.2020.02.001 |
0.328 |
|
| 2020 |
Dees C, Pötter S, Zhang Y, Bergmann C, Zhou X, Luber M, Wohlfahrt T, Karouzakis E, Ramming A, Gelse K, Yoshimura A, Jaenisch R, Distler O, Schett G, Distler JH. TGFβ-induced epigenetic deregulation of SOCS3 facilitates STAT3-signaling to promote fibrosis. The Journal of Clinical Investigation. PMID 31990678 DOI: 10.1172/Jci122462 |
0.345 |
|
| 2019 |
Svoboda DS, Barrasa MI, Shu J, Rietjens R, Zhang S, Mitalipova M, Berube P, Fu D, Shultz LD, Bell GW, Jaenisch R. Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31772018 DOI: 10.1073/Pnas.1913541116 |
0.403 |
|
| 2019 |
Liu XS, Jaenisch R. Editing the Epigenome to Tackle Brain Disorders. Trends in Neurosciences. PMID 31706628 DOI: 10.1016/J.Tins.2019.10.003 |
0.328 |
|
| 2019 |
Song Y, van den Berg PR, Markoulaki S, Soldner F, Dall'Agnese A, Henninger JE, Drotar J, Rosenau N, Cohen MA, Young RA, Semrau S, Stelzer Y, Jaenisch R. Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs. Molecular Cell. PMID 31422875 DOI: 10.1016/J.Molcel.2019.06.045 |
0.535 |
|
| 2019 |
Tang X, Drotar J, Li K, Clairmont CD, Brumm AS, Sullins AJ, Wu H, Liu XS, Wang J, Gray NS, Sur M, Jaenisch R. Pharmacological enhancement of gene expression exerts therapeutic effects on human Rett syndrome neurons and mutant mice. Science Translational Medicine. 11. PMID 31366578 DOI: 10.1126/Scitranslmed.Aau0164 |
0.344 |
|
| 2019 |
Tian TV, Di Stefano B, Stik G, Vila-Casadesús M, Sardina JL, Vidal E, Dasti A, Segura-Morales C, De Andrés-Aguayo L, Gómez A, Goldmann J, Jaenisch R, Graf T. Whsc1 links pluripotency exit with mesendoderm specification. Nature Cell Biology. PMID 31235934 DOI: 10.1038/S41556-019-0342-1 |
0.44 |
|
| 2019 |
Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019072 DOI: 10.1073/Pnas.1900867116 |
0.756 |
|
| 2019 |
Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, Theunissen TW, Jaenisch R, Trono D. Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs. Cell Stem Cell. PMID 31006620 DOI: 10.1016/J.Stem.2019.03.012 |
0.387 |
|
| 2019 |
Schiebinger G, Shu J, Tabaka M, Cleary B, Subramanian V, Solomon A, Gould J, Liu S, Lin S, Berube P, Lee L, Chen J, Brumbaugh J, Rigollet P, Hochedlinger K, ... Jaenisch R, et al. Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming. Cell. PMID 30712874 DOI: 10.1016/J.Cell.2019.01.006 |
0.382 |
|
| 2018 |
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, ... ... Jaenisch R, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028 |
0.78 |
|
| 2018 |
Soldner F, Jaenisch R. Stem Cells, Genome Editing, and the Path to Translational Medicine. Cell. 175: 615-632. PMID 30340033 DOI: 10.1016/J.Cell.2018.09.010 |
0.41 |
|
| 2018 |
Omer Javed A, Li Y, Muffat J, Su KC, Cohen MA, Lungjangwa T, Aubourg P, Cheeseman IM, Jaenisch R. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5. PMID 30304678 DOI: 10.1016/J.Celrep.2018.09.032 |
0.743 |
|
| 2018 |
Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD. One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation. The Journal of Experimental Medicine. PMID 30181412 DOI: 10.1084/Jem.20172064 |
0.338 |
|
| 2018 |
Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R. Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915057 DOI: 10.1073/Pnas.1719266115 |
0.753 |
|
| 2018 |
Cohen MA, Markoulaki S, Jaenisch R. Matched Developmental Timing of Donor Cells with the Host Is Crucial for Chimera Formation. Stem Cell Reports. PMID 29606614 DOI: 10.1016/J.Stemcr.2018.03.004 |
0.386 |
|
| 2018 |
Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R. Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas. Proceedings of the National Academy of Sciences of the United States of America. PMID 29599125 DOI: 10.1073/Pnas.1702059115 |
0.382 |
|
| 2018 |
Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors. Molecular Psychiatry. 23: 791. PMID 29565043 DOI: 10.1038/Mp.2018.5 |
0.381 |
|
| 2018 |
Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/J.Cell.2018.01.012 |
0.806 |
|
| 2018 |
Zabala M, Lobo NA, Seoane JA, Stelzer Y, Luong AV, Isobe T, Zarnegar MA, Watanabe N, Antoñana S, Lam J, Qian D, Sikandar SS, Kuo AH, Heitink LS, Shimono Y, ... ... Jaenisch R, et al. Abstract B67: The DLK1-DIO3 imprinted region regulates long-term proliferation in normal and malignant breast epithelium Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B67 |
0.322 |
|
| 2017 |
Theunissen TW, Jaenisch R. Mechanisms of gene regulation in human embryos and pluripotent stem cells. Development (Cambridge, England). 144: 4496-4509. PMID 29254992 DOI: 10.1242/Dev.157404 |
0.459 |
|
| 2017 |
Weintraub AS, Li CH, Zamudio AV, Sigova AA, Hannett NM, Day DS, Abraham BJ, Cohen MA, Nabet B, Buckley DL, Guo YE, Hnisz D, Jaenisch R, Bradner JE, Gray NS, et al. YY1 Is a Structural Regulator of Enhancer-Promoter Loops. Cell. 171: 1573-1588.e28. PMID 29224777 DOI: 10.1016/J.Cell.2017.11.008 |
0.486 |
|
| 2017 |
Semrau S, Goldmann JE, Soumillon M, Mikkelsen TS, Jaenisch R, van Oudenaarden A. Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells. Nature Communications. 8: 1096. PMID 29061959 DOI: 10.1038/s41467-017-01076-4 |
0.345 |
|
| 2017 |
Pei D, Beier DW, Levy-Lahad E, Marchant G, Rossant J, Izpisua Belmonte JC, Lovell-Badge R, Jaenisch R, Charo A, Baltimore D. Human Embryo Editing: Opportunities and Importance of Transnational Cooperation. Cell Stem Cell. 21: 423-426. PMID 28985523 DOI: 10.1016/J.Stem.2017.09.010 |
0.463 |
|
| 2017 |
Harikumar A, Edupuganti RR, Sorek M, Azad GK, Markoulaki S, Sehnalová P, Legartová S, Bártová E, Farkash-Amar S, Jaenisch R, Alon U, Meshorer E. An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells. Stem Cell Reports. PMID 28966122 DOI: 10.1016/J.Stemcr.2017.08.022 |
0.34 |
|
| 2017 |
Edupuganti RR, Harikumar A, Aaronson Y, Biran A, Sailaja BS, Nissim-Rafinia M, Azad GK, Cohen MA, Park JE, Shivalila CS, Markoulaki S, Sze SK, Jaenisch R, Meshorer E. Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation. Stem Cell Reports. PMID 28966118 DOI: 10.1016/J.Stemcr.2017.08.021 |
0.428 |
|
| 2017 |
Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Molecular Psychiatry. PMID 28439102 DOI: 10.1038/Mp.2017.86 |
0.398 |
|
| 2017 |
Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jaenisch R, Nestler EJ. Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28074830 DOI: 10.1038/Npp.2017.6 |
0.437 |
|
| 2016 |
Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017 |
0.74 |
|
| 2016 |
Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. PMID 27989770 DOI: 10.1016/J.Stem.2016.10.006 |
0.737 |
|
| 2016 |
Wu J, Greely HT, Jaenisch R, Nakauchi H, Rossant J, Belmonte JC. Stem cells and interspecies chimaeras. Nature. 540: 51-59. PMID 27905428 DOI: 10.1038/Nature20573 |
0.371 |
|
| 2016 |
Banerjee A, Rikhye RV, Breton-Provencher V, Tang X, Li C, Li K, Runyan CA, Fu Z, Jaenisch R, Sur M. Jointly reduced inhibition and excitation underlies circuit-wide changes in cortical processing in Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27803317 DOI: 10.1073/Pnas.1615330113 |
0.323 |
|
| 2016 |
Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103. PMID 27768957 DOI: 10.1016/J.Ceb.2016.10.001 |
0.764 |
|
| 2016 |
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine. PMID 27668937 DOI: 10.1038/Nm.4189 |
0.78 |
|
| 2016 |
Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R. Editing DNA Methylation in the Mammalian Genome. Cell. 167: 233-247.e17. PMID 27662091 DOI: 10.1016/J.Cell.2016.08.056 |
0.547 |
|
| 2016 |
Stelzer Y, Wu H, Song Y, Shivalila CS, Markoulaki S, Jaenisch R. Parent-of-Origin DNA Methylation Dynamics during Mouse Development. Cell Reports. 16: 3167-80. PMID 27653683 DOI: 10.1016/J.Celrep.2016.08.066 |
0.4 |
|
| 2016 |
Theunissen TW, Friedli M, He Y, Planet E, O'Neil RC, Markoulaki S, Pontis J, Wang H, Iouranova A, Imbeault M, Duc J, Cohen MA, Wert KJ, Castanon R, Zhang Z, ... ... Jaenisch R, et al. Molecular Criteria for Defining the Naive Human Pluripotent State. Cell Stem Cell. PMID 27424783 DOI: 10.1016/J.Stem.2016.06.011 |
0.417 |
|
| 2016 |
Hockemeyer D, Jaenisch R. Induced Pluripotent Stem Cells Meet Genome Editing. Cell Stem Cell. 18: 573-86. PMID 27152442 DOI: 10.1016/J.Stem.2016.04.013 |
0.684 |
|
| 2016 |
Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, Barrasa MI, Goldmann J, Myers RH, Young RA, Jaenisch R. Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression. Nature. PMID 27096366 DOI: 10.1038/Nature17939 |
0.523 |
|
| 2016 |
Hnisz D, Weintraub AS, Day DS, Valton AL, Bak RO, Li CH, Goldmann J, Lajoie BR, Fan ZP, Sigova AA, Reddy J, Borges-Rivera D, Lee TI, Jaenisch R, Porteus MH, et al. Activation of proto-oncogenes by disruption of chromosome neighborhoods. Science (New York, N.Y.). PMID 26940867 DOI: 10.1126/Science.Aad9024 |
0.506 |
|
| 2016 |
Cohen MA, Wert KJ, Goldmann J, Markoulaki S, Buganim Y, Fu D, Jaenisch R. Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811475 DOI: 10.1073/Pnas.1525518113 |
0.425 |
|
| 2016 |
Carroll B, Maetzel D, Maddocks OD, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. Elife. 5. PMID 26742086 DOI: 10.7554/Elife.11058 |
0.316 |
|
| 2015 |
Ji X, Dadon DB, Powell BE, Fan ZP, Borges-Rivera D, Shachar S, Weintraub AS, Hnisz D, Pegoraro G, Lee TI, Misteli T, Jaenisch R, Young RA. 3D Chromosome Regulatory Landscape of Human Pluripotent Cells. Cell Stem Cell. PMID 26686465 DOI: 10.1016/J.Stem.2015.11.007 |
0.562 |
|
| 2015 |
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Corrigendum: Hallmarks of pluripotency. Nature. PMID 26675727 DOI: 10.1038/Nature16470 |
0.623 |
|
| 2015 |
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Jaenisch R, et al. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. PMID 26675720 DOI: 10.1038/Nature16479 |
0.581 |
|
| 2015 |
Hochedlinger K, Jaenisch R. Induced Pluripotency and Epigenetic Reprogramming. Cold Spring Harbor Perspectives in Biology. 7. PMID 26626939 DOI: 10.1101/Cshperspect.A019448 |
0.414 |
|
| 2015 |
Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... ... Jaenisch R, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011 |
0.537 |
|
| 2015 |
D'Alessio AC, Fan ZP, Wert KJ, Baranov P, Cohen MA, Saini JS, Cohick E, Charniga C, Dadon D, Hannett NM, Young MJ, Temple S, Jaenisch R, Lee TI, Young RA. A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity. Stem Cell Reports. PMID 26603904 DOI: 10.1016/J.Stemcr.2015.09.016 |
0.564 |
|
| 2015 |
Wiehle L, Raddatz G, Musch T, Dawlaty MM, Jaenisch R, Lyko F, Breiling A. Tet1 and Tet2 protect DNA methylation canyons against hypermethylation. Molecular and Cellular Biology. PMID 26598602 DOI: 10.1128/Mcb.00587-15 |
0.387 |
|
| 2015 |
Stelzer Y, Jaenisch R. Monitoring Dynamics of DNA Methylation at Single-Cell Resolution during Development and Disease. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26432525 DOI: 10.1101/Sqb.2015.80.027334 |
0.372 |
|
| 2015 |
Stelzer Y, Shivalila CS, Soldner F, Markoulaki S, Jaenisch R. Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution. Cell. 163: 218-29. PMID 26406378 DOI: 10.1016/J.Cell.2015.08.046 |
0.418 |
|
| 2015 |
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Jaenisch R, et al. Failure to replicate the STAP cell phenomenon. Nature. 525: E6-9. PMID 26399835 DOI: 10.1038/Nature15513 |
0.581 |
|
| 2015 |
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Hallmarks of pluripotency. Nature. 525: 469-78. PMID 26399828 DOI: 10.1038/Nature15515 |
0.653 |
|
| 2015 |
Jaenisch R. Stem Cell Research: Promise and Progress. Stem Cell Reports. 4: 953-4. PMID 26070609 DOI: 10.1016/J.Stemcr.2015.05.015 |
0.356 |
|
| 2015 |
Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YS, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, Mullenders J, King B, Trimarchi T, Aranda-Orgilles B, Liu C, ... ... Jaenisch R, et al. TET1 is a tumor suppressor of hematopoietic malignancy. Nature Immunology. 16: 653-62. PMID 25867473 DOI: 10.1038/Ni.3148 |
0.414 |
|
| 2015 |
Soldner F, Jaenisch R. Dissecting risk haplotypes in sporadic Alzheimer's disease. Cell Stem Cell. 16: 341-2. PMID 25842969 DOI: 10.1016/J.Stem.2015.03.010 |
0.328 |
|
| 2015 |
Ji X, Dadon DB, Abraham BJ, Lee TI, Jaenisch R, Bradner JE, Young RA. Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions. Proceedings of the National Academy of Sciences of the United States of America. 112: 3841-6. PMID 25755260 DOI: 10.1073/Pnas.1502971112 |
0.485 |
|
| 2015 |
Deuse T, Wang D, Stubbendorff M, Itagaki R, Grabosch A, Greaves LC, Alawi M, Grünewald A, Hu X, Hua X, Velden J, Reichenspurner H, Robbins RC, Jaenisch R, Weissman IL, et al. SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts. Cell Stem Cell. 16: 33-8. PMID 25465116 DOI: 10.1016/J.Stem.2014.11.003 |
0.352 |
|
| 2015 |
Ntziachristos P, Welstead G, Trimarchi T, Bakogianni S, Xu L, Vlierberghe PV, Prinjha R, Ferrando A, Jaenisch R, Mullighan C, Iannis A. Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-Pr03 |
0.33 |
|
| 2015 |
Ntziachristos P, Welstead G, Trimarchi T, Bakogianni S, Xu L, Vlierberghe PV, Prinjha R, Ferrando A, Jaenisch R, Mullighan C, Iannis A. Abstract B24: Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia. Epigenetics. DOI: 10.1158/1557-3265.Hemmal14-B24 |
0.321 |
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| 2015 |
Dougan SK, Bilate A, Jaenisch R, Ploegh HL. Abstract B59: Transnuclear mice as models of the immune response to pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B59 |
0.318 |
|
| 2015 |
Semrau S, Goldmann J, Soumillon M, Mikkelsen T, Jaenisch R, van Oudenaarden A. Early Lineage Bifurcation during Differentiation of Embryonic Stem Cells Revealed by Single-Cell Transcriptomics Biophysical Journal. 108: 365a. DOI: 10.1016/J.Bpj.2014.11.2001 |
0.422 |
|
| 2014 |
Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency. Cell Stem Cell. 15: 524-526. PMID 28903030 DOI: 10.1016/j.stem.2014.09.003 |
0.377 |
|
| 2014 |
Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency. Cell Stem Cell. 15: 523. PMID 28903029 DOI: 10.1016/J.Stem.2014.08.002 |
0.455 |
|
| 2014 |
Cassady JP, D'Alessio AC, Sarkar S, Dani VS, Fan ZP, Ganz K, Roessler R, Sur M, Young RA, Jaenisch R. Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells. Stem Cell Reports. 3: 948-56. PMID 25454632 DOI: 10.1016/J.Stemcr.2014.10.001 |
0.586 |
|
| 2014 |
Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B. Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication. Plos One. 9: e112413. PMID 25390032 DOI: 10.1371/Journal.Pone.0112413 |
0.4 |
|
| 2014 |
Katz Y, Li F, Lambert NJ, Sokol ES, Tam WL, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. Elife. 3: e03915. PMID 25380226 DOI: 10.7554/Elife.03915 |
0.328 |
|
| 2014 |
Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, Kulenkampff E, Faddah DA, Shi L, Gao Q, Sarkar S, ... ... Jaenisch R, et al. The developmental potential of iPSCs is greatly influenced by reprogramming factor selection. Cell Stem Cell. 15: 295-309. PMID 25192464 DOI: 10.1016/J.Stem.2014.07.003 |
0.555 |
|
| 2014 |
Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D. Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation. Genes & Development. 28: 1885-99. PMID 25128433 DOI: 10.1101/Gad.246819.114 |
0.71 |
|
| 2014 |
Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic identification of culture conditions for induction and maintenance of naive human pluripotency. Cell Stem Cell. 15: 471-87. PMID 25090446 DOI: 10.1016/J.Stem.2014.07.002 |
0.483 |
|
| 2014 |
Yang H, Wang H, Jaenisch R. Generating genetically modified mice using CRISPR/Cas-mediated genome engineering. Nature Protocols. 9: 1956-68. PMID 25058643 DOI: 10.1038/Nprot.2014.134 |
0.39 |
|
| 2014 |
Maetzel D, Sarkar S, Wang H, Abi-Mosleh L, Xu P, Cheng AW, Gao Q, Mitalipova M, Jaenisch R. Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells. Stem Cell Reports. 2: 866-80. PMID 24936472 DOI: 10.1016/J.Stemcr.2014.03.014 |
0.366 |
|
| 2014 |
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, ... Jaenisch R, et al. Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells. Stem Cell Reports. 2: 838-52. PMID 24936470 DOI: 10.1016/J.Stemcr.2014.05.001 |
0.7 |
|
| 2014 |
Theunissen TW, Jaenisch R. Molecular control of induced pluripotency. Cell Stem Cell. 14: 720-34. PMID 24905163 DOI: 10.1016/J.Stem.2014.05.002 |
0.393 |
|
| 2014 |
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889 |
0.506 |
|
| 2014 |
Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G, Gao Q, Powell BE, Cheng AW, Faull KF, Lyko F, Jaenisch R. Loss of Tet enzymes compromises proper differentiation of embryonic stem cells. Developmental Cell. 29: 102-11. PMID 24735881 DOI: 10.1016/J.Devcel.2014.03.003 |
0.58 |
|
| 2014 |
Klemm S, Semrau S, Wiebrands K, Mooijman D, Faddah DA, Jaenisch R, van Oudenaarden A. Transcriptional profiling of cells sorted by RNA abundance. Nature Methods. 11: 549-51. PMID 24681693 DOI: 10.1038/Nmeth.2910 |
0.375 |
|
| 2014 |
Armond JW, Saha K, Rana AA, Oates CJ, Jaenisch R, Nicodemi M, Mukherjee S. A stochastic model dissects cell states in biological transition processes. Scientific Reports. 4: 3692. PMID 24435049 DOI: 10.1038/Srep03692 |
0.36 |
|
| 2014 |
Katz Y, Li F, Lambert NJ, Sokol ES, Tam W, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB. Author response: Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state Elife. DOI: 10.7554/Elife.03915.025 |
0.326 |
|
| 2014 |
Forster R, Chiba K, Schaeffer L, Regalado S, Lai C, Gao Q, Kiani S, Farin H, Clevers H, Cost G, Chan A, Rebar E, Urnov F, Gregory P, Pachter L, ... Jaenisch R, et al. Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells Stem Cell Reports. 3: 215. DOI: 10.1016/J.Stemcr.2014.06.014 |
0.69 |
|
| 2014 |
Theunissen T, Powell B, Wang H, Mitalipova M, Faddah D, Reddy J, Fan Z, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency (DOI:10.1016/j.stem.2014.07.002) Cell Stem Cell. DOI: 10.1016/j.stem.2014.08.002 |
0.424 |
|
| 2013 |
Dougan SK, Dougan M, Kim J, Turner JA, Ogata S, Cho HI, Jaenisch R, Celis E, Ploegh HL. Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity. Cancer Immunology Research. 1: 99-111. PMID 24459675 DOI: 10.1158/2326-6066.Cir-13-0047 |
0.337 |
|
| 2013 |
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Jaenisch R, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296 |
0.791 |
|
| 2013 |
Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, ... ... Jaenisch R, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/J.Stem.2013.09.001 |
0.808 |
|
| 2013 |
Rudenko A, Dawlaty MM, Seo J, Cheng AW, Meng J, Le T, Faull KF, Jaenisch R, Tsai LH. Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron. 79: 1109-22. PMID 24050401 DOI: 10.1016/J.Neuron.2013.08.003 |
0.571 |
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| 2013 |
Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, Jaenisch R. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell. 154: 1370-9. PMID 23992847 DOI: 10.1016/J.Cell.2013.08.022 |
0.344 |
|
| 2013 |
Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R. Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Research. 23: 1163-71. PMID 23979020 DOI: 10.1038/Cr.2013.122 |
0.368 |
|
| 2013 |
Faddah DA, Wang H, Cheng AW, Katz Y, Buganim Y, Jaenisch R. Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs. Cell Stem Cell. 13: 23-9. PMID 23827708 DOI: 10.1016/J.Stem.2013.04.019 |
0.458 |
|
| 2013 |
Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, ... ... Jaenisch R, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11994-9. PMID 23818607 DOI: 10.1073/Pnas.1310656110 |
0.43 |
|
| 2013 |
Torikai H, Reik A, Soldner F, Warren EH, Yuen C, Zhou Y, Crossland DL, Huls H, Littman N, Zhang Z, Tykodi SS, Kebriaei P, Lee DA, Miller JC, Rebar EJ, ... ... Jaenisch R, et al. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood. 122: 1341-9. PMID 23741009 DOI: 10.1182/Blood-2013-03-478255 |
0.371 |
|
| 2013 |
Buganim Y, Faddah DA, Jaenisch R. Mechanisms and models of somatic cell reprogramming. Nature Reviews. Genetics. 14: 427-39. PMID 23681063 DOI: 10.1038/nrg3473 |
0.323 |
|
| 2013 |
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 153: 910-8. PMID 23643243 DOI: 10.1016/J.Cell.2013.04.025 |
0.372 |
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| 2013 |
Piccolo FM, Bagci H, Brown KE, Landeira D, Soza-Ried J, Feytout A, Mooijman D, Hajkova P, Leitch HG, Tada T, Kriaucionis S, Dawlaty MM, Jaenisch R, Merkenschlager M, Fisher AG. Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion. Molecular Cell. 49: 1023-33. PMID 23453809 DOI: 10.1016/j.molcel.2013.01.032 |
0.355 |
|
| 2013 |
Lodato MA, Ng CW, Wamstad JA, Cheng AW, Thai KK, Fraenkel E, Jaenisch R, Boyer LA. SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state. Plos Genetics. 9: e1003288. PMID 23437007 DOI: 10.1371/Journal.Pgen.1003288 |
0.83 |
|
| 2013 |
Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Developmental Cell. 24: 310-23. PMID 23352810 DOI: 10.1016/J.Devcel.2012.12.015 |
0.533 |
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| 2013 |
Avalos AM, Kirak O, Oelkers JM, Pils MC, Kim YM, Ottinger M, Jaenisch R, Ploegh HL, Brinkmann MM. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 695-702. PMID 23241879 DOI: 10.4049/Jimmunol.1202342 |
0.317 |
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| 2013 |
Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y. Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Development (Cambridge, England). 140: 66-75. PMID 23222438 DOI: 10.1242/Jcs.130047 |
0.376 |
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| 2013 |
Ntziachristos P, Tsirigos A, Trimarchi T, Loizou E, Luyao X, Vlierberghe PV, King B, Welstead G, Mullighan C, Jaenisch R, Ferrando A, Aifantis I. Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A07 |
0.377 |
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| 2013 |
Ricklefs F, Hua X, Velden J, Kirak O, Jaenisch R, Weissman I, Reichenspurner H. Immunobiology of embryonic stem cells: Foreign mtDNA as an immunological barrier in SCNT derived embryonic stem cells transplantation The Thoracic and Cardiovascular Surgeon. 61. DOI: 10.1055/S-0032-1332452 |
0.391 |
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| 2013 |
Piccolo FM, Bagci H, Brown KE, Landeira D, Soza-Ried J, Feytout A, Mooijman D, Hajkova P, Leitch HG, Tada T, Kriaucionis S, Dawlaty MM, Jaenisch R, Merkenschlager M, Fisher AG. Errata to Different roles for tet1 and tet2 proteins in reprogramming-mediated erasure of imprints induced by egc fusion [Molecular Cell, 49 (2013) 1023-1033] Molecular Cell. 49: 1176. DOI: 10.1016/J.Molcel.2013.03.011 |
0.345 |
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| 2013 |
Yamanaka S, Wagers A, Muotri A, Srivastava D, Melton D, Blanpain C, Gurdon J, Fuchs E, Jaenisch R. XStem cells in translation Cell. 153: X1177-1179. DOI: 10.1016/J.Cell.2013.05.036 |
0.371 |
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| 2012 |
Raddatz G, Gao Q, Bender S, Jaenisch R, Lyko F. Dnmt3a protects active chromosome domains against cancer-associated hypomethylation. Plos Genetics. 8: e1003146. PMID 23284304 DOI: 10.1371/Journal.Pgen.1003146 |
0.33 |
|
| 2012 |
Soldner F, Jaenisch R. Medicine. iPSC disease modeling. Science (New York, N.Y.). 338: 1155-6. PMID 23197518 DOI: 10.1126/Science.1227682 |
0.389 |
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| 2012 |
Buganim Y, Jaenisch R. Transdifferentiation by defined factors as a powerful research tool to address basic biological questions. Cell Cycle (Georgetown, Tex.). 11: 4485-6. PMID 23165203 DOI: 10.4161/Cc.22665 |
0.483 |
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| 2012 |
Buganim Y, Faddah DA, Cheng AW, Itskovich E, Markoulaki S, Ganz K, Klemm SL, van Oudenaarden A, Jaenisch R. Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell. 150: 1209-22. PMID 22980981 DOI: 10.1016/j.cell.2012.08.023 |
0.315 |
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| 2012 |
Buganim Y, Itskovich E, Hu YC, Cheng AW, Ganz K, Sarkar S, Fu D, Welstead GG, Page DC, Jaenisch R. Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors. Cell Stem Cell. 11: 373-86. PMID 22958931 DOI: 10.1016/J.Stem.2012.07.019 |
0.461 |
|
| 2012 |
Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL. IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 13739-44. PMID 22869725 DOI: 10.1073/Pnas.1210273109 |
0.34 |
|
| 2012 |
Welstead GG, Creyghton MP, Bilodeau S, Cheng AW, Markoulaki S, Young RA, Jaenisch R. X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 109: 13004-9. PMID 22826230 DOI: 10.1073/Pnas.1210787109 |
0.538 |
|
| 2012 |
Hua X, Deuse T, Velden J, Kirak O, Jaenisch R, Weissman I, Ricklefs F, Reichenspurner H, Robbins RC, Schrepfer S. Immunobiology of SCNT Derived Embryonic Stem Cells: Pivotal Role of mtDNA in Rejection of Transplanted Stem Cells Transplantation Journal. 94: 113. DOI: 10.1097/00007890-201211271-00208 |
0.383 |
|
| 2012 |
Hua X, Deuse T, Velden J, Kirak O, Jaenisch R, Weissman I, Ricklefs F, Reichenspurner H, Robbins R, Schrepfer S. 330 Regenerative Therapy after Myocardial Infarction: Role of mtDNA in SCNT Derived Embryonic Stem Cells The Journal of Heart and Lung Transplantation. 31: S117. DOI: 10.1016/J.Healun.2012.01.338 |
0.338 |
|
| 2011 |
Carey BW, Markoulaki S, Hanna JH, Faddah DA, Buganim Y, Kim J, Ganz K, Steine EJ, Cassady JP, Creyghton MP, Welstead GG, Gao Q, Jaenisch R. Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. Cell Stem Cell. 9: 588-98. PMID 22136932 DOI: 10.1016/J.Stem.2011.11.003 |
0.459 |
|
| 2011 |
Saha K, Mei Y, Reisterer CM, Pyzocha NK, Yang J, Muffat J, Davies MC, Alexander MR, Langer R, Anderson DG, Jaenisch R. Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America. 108: 18714-9. PMID 22065768 DOI: 10.1073/Pnas.1114854108 |
0.756 |
|
| 2011 |
Kim J, Su SC, Wang H, Cheng AW, Cassady JP, Lodato MA, Lengner CJ, Chung CY, Dawlaty MM, Tsai LH, Jaenisch R. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell. 9: 413-9. PMID 22019014 DOI: 10.1016/J.Stem.2011.09.011 |
0.757 |
|
| 2011 |
Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R. Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 108: 18061-6. PMID 22011581 DOI: 10.1073/Pnas.1114946108 |
0.658 |
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| 2011 |
Chu LF, Surani MA, Jaenisch R, Zwaka TP. Blimp1 expression predicts embryonic stem cell development in vitro. Current Biology : Cb. 21: 1759-65. PMID 22000107 DOI: 10.1016/J.Cub.2011.09.010 |
0.477 |
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| 2011 |
Major T, Menon J, Auyeung G, Soldner F, Hockemeyer D, Jaenisch R, Tabar V. Transgene excision has no impact on in vivo integration of human iPS derived neural precursors. Plos One. 6: e24687. PMID 21961042 DOI: 10.1371/Journal.Pone.0024687 |
0.692 |
|
| 2011 |
Medeiros LA, Dennis LM, Gill ME, Houbaviy H, Markoulaki S, Fu D, White AC, Kirak O, Sharp PA, Page DC, Jaenisch R. Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. Proceedings of the National Academy of Sciences of the United States of America. 108: 14163-8. PMID 21844366 DOI: 10.1073/Pnas.1111241108 |
0.466 |
|
| 2011 |
Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell. 9: 166-75. PMID 21816367 DOI: 10.1016/J.Stem.2011.07.010 |
0.418 |
|
| 2011 |
Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, ... ... Jaenisch R, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell. 146: 318-31. PMID 21757228 DOI: 10.1016/J.Cell.2011.06.019 |
0.803 |
|
| 2011 |
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, ... ... Jaenisch R, et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nature Biotechnology. 29: 731-4. PMID 21738127 DOI: 10.1038/Nbt.1927 |
0.709 |
|
| 2011 |
Pawlak M, Jaenisch R. De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes & Development. 25: 1035-40. PMID 21576263 DOI: 10.1101/Gad.2039011 |
0.447 |
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| 2011 |
Zheng GX, Ravi A, Calabrese JM, Medeiros LA, Kirak O, Dennis LM, Jaenisch R, Burge CB, Sharp PA. A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells. Plos Genetics. 7: e1002054. PMID 21573140 DOI: 10.1371/Journal.Pgen.1002054 |
0.473 |
|
| 2011 |
Kim J, Lengner CJ, Kirak O, Hanna J, Cassady JP, Lodato MA, Wu S, Faddah DA, Steine EJ, Gao Q, Fu D, Dawlaty M, Jaenisch R. Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors. Stem Cells (Dayton, Ohio). 29: 992-1000. PMID 21563275 DOI: 10.1002/Stem.641 |
0.769 |
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| 2011 |
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, ... Jaenisch R, et al. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International Ed. in English). 50: 5734-6. PMID 21547985 DOI: 10.1002/Anie.201101042 |
0.423 |
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| 2011 |
Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, Jaenisch R, Linhart HG. Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. The Journal of Clinical Investigation. 121: 1748-52. PMID 21490393 DOI: 10.1172/Jci43169 |
0.409 |
|
| 2010 |
Hockemeyer D, Jaenisch R. Gene targeting in human pluripotent cells. Cold Spring Harbor Symposia On Quantitative Biology. 75: 201-9. PMID 21209393 DOI: 10.1101/Sqb.2010.75.021 |
0.731 |
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| 2010 |
Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proceedings of the National Academy of Sciences of the United States of America. 107: 21931-6. PMID 21106759 DOI: 10.1073/Pnas.1016071107 |
0.81 |
|
| 2010 |
Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell. 143: 508-25. PMID 21074044 DOI: 10.1016/J.Cell.2010.10.008 |
0.351 |
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| 2010 |
Kirak O, Frickel EM, Grotenbreg GM, Suh H, Jaenisch R, Ploegh HL. Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT. Journal of Visualized Experiments : Jove. PMID 20972401 DOI: 10.3791/2168 |
0.408 |
|
| 2010 |
Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL. T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proceedings of the National Academy of Sciences of the United States of America. 107: 18939-43. PMID 20956329 DOI: 10.1073/Pnas.1013230107 |
0.427 |
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| 2010 |
Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, Yow A, Soldner F, Hockemeyer D, Hallett PJ, Osborn T, Jaenisch R, Isacson O. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proceedings of the National Academy of Sciences of the United States of America. 107: 15921-6. PMID 20798034 DOI: 10.1073/Pnas.1010209107 |
0.674 |
|
| 2010 |
Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH. Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. Journal of Immunology (Baltimore, Md. : 1950). 185: 3564-73. PMID 20709953 DOI: 10.4049/Jimmunol.0903098 |
0.381 |
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| 2010 |
Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA. Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell. 7: 249-57. PMID 20682450 DOI: 10.1016/J.Stem.2010.06.015 |
0.76 |
|
| 2010 |
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, ... ... Jaenisch R, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 467: 285-90. PMID 20644535 DOI: 10.1038/Nature09342 |
0.458 |
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| 2010 |
Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, Mostoslavsky G, Jaenisch R. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell. 7: 20-4. PMID 20621045 DOI: 10.1016/J.Stem.2010.06.002 |
0.42 |
|
| 2010 |
DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, ... ... Jaenisch R, et al. Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Research. 20: 1133-42. PMID 20508142 DOI: 10.1101/Gr.106773.110 |
0.68 |
|
| 2010 |
Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, ... Jaenisch R, et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell. 141: 872-83. PMID 20471072 DOI: 10.1016/J.Cell.2010.04.010 |
0.815 |
|
| 2010 |
Hanna J, Cheng AW, Saha K, Kim J, Lengner CJ, Soldner F, Cassady JP, Muffat J, Carey BW, Jaenisch R. Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proceedings of the National Academy of Sciences of the United States of America. 107: 9222-7. PMID 20442331 DOI: 10.1073/Pnas.1004584107 |
0.774 |
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| 2010 |
Namekawa SH, Payer B, Huynh KD, Jaenisch R, Lee JT. Two-step imprinted X inactivation: repeat versus genic silencing in the mouse. Molecular and Cellular Biology. 30: 3187-205. PMID 20404085 DOI: 10.1128/Mcb.00227-10 |
0.547 |
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| 2010 |
Kirak O, Frickel EM, Grotenbreg GM, Suh H, Jaenisch R, Ploegh HL. Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT. Science (New York, N.Y.). 328: 243-8. PMID 20378817 DOI: 10.1126/Science.1178590 |
0.368 |
|
| 2010 |
Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Generation of iPSCs from cultured human malignant cells. Blood. 115: 4039-42. PMID 20233975 DOI: 10.1182/Blood-2009-07-231845 |
0.677 |
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| 2010 |
Dressel R, Nolte J, Elsner L, Novota P, Guan K, Streckfuss-Bömeke K, Hasenfuss G, Jaenisch R, Engel W. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2164-77. PMID 20145206 DOI: 10.1096/Fj.09-134957 |
0.421 |
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| 2010 |
Yang-Iott KS, Carpenter AC, Rowh MA, Steinel N, Brady BL, Hochedlinger K, Jaenisch R, Bassing CH. TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes. Journal of Immunology (Baltimore, Md. : 1950). 184: 1369-78. PMID 20042591 DOI: 10.4049/Jimmunol.0900723 |
0.303 |
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| 2010 |
Carey BW, Markoulaki S, Beard C, Hanna J, Jaenisch R. Single-gene transgenic mouse strains for reprogramming adult somatic cells. Nature Methods. 7: 56-9. PMID 20010831 DOI: 10.1038/Nmeth.1410 |
0.453 |
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| 2009 |
Saha K, Jaenisch R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell. 5: 584-95. PMID 19951687 DOI: 10.1016/J.Stem.2009.11.009 |
0.369 |
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| 2009 |
Hanna J, Saha K, Pando B, van Zon J, Lengner CJ, Creyghton MP, van Oudenaarden A, Jaenisch R. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature. 462: 595-601. PMID 19898493 DOI: 10.1038/Nature08592 |
0.443 |
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| 2009 |
Bröske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, Kuhl C, Enns A, Prinz M, Jaenisch R, Nerlov C, Leutz A, Andrade-Navarro MA, Jacobsen SE, Rosenbauer F. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature Genetics. 41: 1207-15. PMID 19801979 DOI: 10.1038/Ng.463 |
0.441 |
|
| 2009 |
Kuzmenkin A, Liang H, Xu G, Pfannkuche K, Eichhorn H, Fatima A, Luo H, Saric T, Wernig M, Jaenisch R, Hescheler J. Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4168-80. PMID 19703934 DOI: 10.1096/Fj.08-128546 |
0.65 |
|
| 2009 |
Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, ... ... Jaenisch R, et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nature Biotechnology. 27: 851-7. PMID 19680244 DOI: 10.1038/Nbt.1562 |
0.725 |
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| 2009 |
Jaenisch R. Stem cells, pluripotency and nuclear reprogramming. Journal of Thrombosis and Haemostasis : Jth. 7: 21-3. PMID 19630760 DOI: 10.1111/j.1538-7836.2009.03418.x |
0.307 |
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| 2009 |
Pfannkuche K, Liang H, Hannes T, Xi J, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J, Reppel M. Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 73-86. PMID 19590195 DOI: 10.1159/000227815 |
0.627 |
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| 2009 |
Nosho K, Shima K, Irahara N, Kure S, Baba Y, Kirkner GJ, Chen L, Gokhale S, Hazra A, Spiegelman D, Giovannucci EL, Jaenisch R, Fuchs CS, Ogino S. DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3663-71. PMID 19470733 DOI: 10.1158/1078-0432.Ccr-08-2383 |
0.32 |
|
| 2009 |
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, ... Jaenisch R, et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8912-7. PMID 19447925 DOI: 10.1073/Pnas.0903860106 |
0.399 |
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| 2009 |
Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, Gao Q, Kim J, Jaenisch R. Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell. 4: 513-24. PMID 19427283 DOI: 10.1016/J.Stem.2009.04.015 |
0.438 |
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| 2009 |
Han DW, Do JT, Araúzo-Bravo MJ, Lee SH, Meissner A, Lee HT, Jaenisch R, Schöler HR. Epigenetic hierarchy governing Nestin expression. Stem Cells (Dayton, Ohio). 27: 1088-97. PMID 19415779 DOI: 10.1002/Stem.43 |
0.433 |
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| 2009 |
Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell. 136: 964-77. PMID 19269371 DOI: 10.1016/J.Cell.2009.02.013 |
0.681 |
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| 2009 |
Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 4: 200-1; author reply . PMID 19265657 DOI: 10.1016/J.Stem.2009.02.009 |
0.761 |
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| 2009 |
Tropea D, Giacometti E, Wilson NR, Beard C, McCurry C, Fu DD, Flannery R, Jaenisch R, Sur M. Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 2029-34. PMID 19208815 DOI: 10.1073/Pnas.0812394106 |
0.302 |
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| 2009 |
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458: 223-7. PMID 19182780 DOI: 10.1038/Nature07672 |
0.374 |
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| 2009 |
Markoulaki S, Hanna J, Beard C, Carey BW, Cheng AW, Lengner CJ, Dausman JA, Fu D, Gao Q, Wu S, Cassady JP, Jaenisch R. Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nature Biotechnology. 27: 169-71. PMID 19151700 DOI: 10.1038/Nbt.1520 |
0.403 |
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| 2009 |
Skelley AM, Kirak O, Suh H, Jaenisch R, Voldman J. Microfluidic control of cell pairing and fusion. Nature Methods. 6: 147-52. PMID 19122668 DOI: 10.1038/Nmeth.1290 |
0.393 |
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| 2009 |
Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, Mitalipova M, Jaenisch R. Reprogramming of murine and human somatic cells using a single polycistronic vector. Proceedings of the National Academy of Sciences of the United States of America. 106: 157-62. PMID 19109433 DOI: 10.1073/Pnas.0811426106 |
0.456 |
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| 2009 |
Meissner A, Eminli S, Jaenisch R. Derivation and manipulation of murine embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 482: 3-19. PMID 19089346 DOI: 10.1007/978-1-59745-060-7_1 |
0.444 |
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| 2009 |
Foudi A, Hochedlinger K, Van Buren D, Schindler JW, Jaenisch R, Carey V, Hock H. Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nature Biotechnology. 27: 84-90. PMID 19060879 DOI: 10.1038/Nbt.1517 |
0.381 |
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| 2009 |
Linhart HG, Troen A, Bell GW, Cantu E, Chao WH, Moran E, Steine E, He T, Jaenisch R. Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations. Gastroenterology. 136: 227-235.e3. PMID 18992744 DOI: 10.1053/J.Gastro.2008.10.016 |
0.366 |
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| 2009 |
Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, Gao Q, Kim J, Jaenisch R. Metastable Pluripotent States in NOD-Mouse-Derived ESCs (DOI:10.1016/j.stem.2008.08.014) Cell Stem Cell. 5: 124. DOI: 10.1016/J.Stem.2009.06.007 |
0.345 |
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| 2009 |
Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors (DOI:10.1016/j.cell.2009.02.013) Cell. 137: 1356. DOI: 10.1016/j.cell.2009.06.017 |
0.665 |
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| 2009 |
Hockemeyer D, Soldner F, Jaenisch R. Direct Reprogramming of Somatic Cells to a Pluripotent State Essentials of Stem Cell Biology. 29-31. DOI: 10.1016/B978-0-12-374729-7.00004-4 |
0.656 |
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| 2008 |
Welstead GG, Brambrink T, Jaenisch R. Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4. Journal of Visualized Experiments : Jove. PMID 19066578 DOI: 10.3791/734 |
0.361 |
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| 2008 |
Hanna J, Carey BW, Jaenisch R. Reprogramming of somatic cell identity. Cold Spring Harbor Symposia On Quantitative Biology. 73: 147-55. PMID 19022760 DOI: 10.1101/sqb.2008.73.025 |
0.355 |
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| 2008 |
Creyghton MP, Markoulaki S, Levine SS, Hanna J, Lodato MA, Sha K, Young RA, Jaenisch R, Boyer LA. H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell. 135: 649-61. PMID 18992931 DOI: 10.1016/J.Cell.2008.09.056 |
0.826 |
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| 2008 |
Hockemeyer D, Soldner F, Cook EG, Gao Q, Mitalipova M, Jaenisch R. A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell Stem Cell. 3: 346-53. PMID 18786421 DOI: 10.1016/J.Stem.2008.08.014 |
0.711 |
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| 2008 |
Green JJ, Zhou BY, Mitalipova MM, Beard C, Langer R, Jaenisch R, Anderson DG. Nanoparticles for gene transfer to human embryonic stem cell colonies. Nano Letters. 8: 3126-30. PMID 18754690 DOI: 10.1021/Nl8012665 |
0.359 |
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| 2008 |
Mathur D, Danford TW, Boyer LA, Young RA, Gifford DK, Jaenisch R. Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biology. 9: R126. PMID 18700969 DOI: 10.1186/Gb-2008-9-8-R126 |
0.755 |
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| 2008 |
Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, ... ... Jaenisch R, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/J.Cell.2008.07.020 |
0.773 |
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| 2008 |
Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell. 3: 132-5. PMID 18682236 DOI: 10.1016/J.Stem.2008.06.019 |
0.621 |
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| 2008 |
Eminli S, Utikal J, Arnold K, Jaenisch R, Hochedlinger K. Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem Cells (Dayton, Ohio). 26: 2467-74. PMID 18635867 DOI: 10.1634/Stemcells.2008-0317 |
0.474 |
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| 2008 |
Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, ... ... Jaenisch R, et al. Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7219-30. PMID 18614692 DOI: 10.1523/Jneurosci.0940-08.2008 |
0.319 |
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| 2008 |
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/Nature07107 |
0.655 |
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| 2008 |
Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature Biotechnology. 26: 916-24. PMID 18594521 DOI: 10.1038/Nbt1483 |
0.804 |
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| 2008 |
Markoulaki S, Meissner A, Jaenisch R. Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse. Methods (San Diego, Calif.). 45: 101-14. PMID 18593608 DOI: 10.1016/J.Ymeth.2008.04.002 |
0.467 |
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| 2008 |
Hirasawa R, Chiba H, Kaneda M, Tajima S, Li E, Jaenisch R, Sasaki H. Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes & Development. 22: 1607-16. PMID 18559477 DOI: 10.1101/Gad.1667008 |
0.37 |
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| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/Nature07056 |
0.689 |
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| 2008 |
Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell. 133: 250-64. PMID 18423197 DOI: 10.1016/J.Cell.2008.03.028 |
0.607 |
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| 2008 |
Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 5856-61. PMID 18391196 DOI: 10.1073/Pnas.0801677105 |
0.64 |
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| 2008 |
Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, Van Neste L, Jaenisch R, Fan G. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell. 2: 160-9. PMID 18371437 DOI: 10.1016/J.Stem.2007.12.011 |
0.795 |
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| 2008 |
Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell. 2: 151-9. PMID 18371436 DOI: 10.1016/J.Stem.2008.01.004 |
0.653 |
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| 2008 |
Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2: 10-2. PMID 18371415 DOI: 10.1016/J.Stem.2007.12.001 |
0.609 |
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| 2008 |
Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR, Jaenisch R, Sharp PA, Jacks T. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 132: 875-86. PMID 18329372 DOI: 10.1016/J.Cell.2008.02.019 |
0.422 |
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| 2008 |
Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell. 132: 567-82. PMID 18295576 DOI: 10.1016/J.Cell.2008.01.015 |
0.565 |
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| 2008 |
Lengner CJ, Welstead GG, Jaenisch R. The pluripotency regulator Oct4: a role in somatic stem cells? Cell Cycle (Georgetown, Tex.). 7: 725-8. PMID 18239456 DOI: 10.4161/Cc.7.6.5573 |
0.424 |
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| 2008 |
Howard G, Eiges R, Gaudet F, Jaenisch R, Eden A. Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene. 27: 404-8. PMID 17621273 DOI: 10.1038/Sj.Onc.1210631 |
0.373 |
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| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis (Nature (2008) 454, (49-55)) Nature. 454: 794. DOI: 10.1038/Nature07196 |
0.561 |
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| 2008 |
Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency (DOI:10.1016/j.cell.2008.03.028) Cell. 134: 365. DOI: 10.1016/j.cell.2008.07.013 |
0.574 |
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| 2007 |
Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S. New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell. 1: 367-8. PMID 18371375 DOI: 10.1016/J.Stem.2007.09.006 |
0.369 |
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| 2007 |
Kim K, Ng K, Rugg-Gunn PJ, Shieh JH, Kirak O, Jaenisch R, Wakayama T, Moore MA, Pedersen RA, Daley GQ. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell. 1: 346-52. PMID 18371368 DOI: 10.1016/J.Stem.2007.07.001 |
0.422 |
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| 2007 |
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 1: 55-70. PMID 18371336 DOI: 10.1016/J.Stem.2007.05.014 |
0.835 |
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| 2007 |
Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S, Scholer HR, Tomilin A, Jaenisch R. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell. 1: 403-15. PMID 18159219 DOI: 10.1016/J.Stem.2007.07.020 |
0.449 |
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| 2007 |
Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/Science.1152092 |
0.678 |
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| 2007 |
Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes & Development. 21: 3110-22. PMID 18056424 DOI: 10.1101/Gad.1594007 |
0.379 |
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| 2007 |
Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR. YAP1 increases organ size and expands undifferentiated progenitor cells. Current Biology : Cb. 17: 2054-60. PMID 17980593 DOI: 10.1016/J.Cub.2007.10.039 |
0.412 |
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| 2007 |
Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. Plos One. 2: e895. PMID 17878930 DOI: 10.1371/Journal.Pone.0000895 |
0.667 |
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| 2007 |
Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology. 25: 1177-81. PMID 17724450 DOI: 10.1038/Nbt1335 |
0.665 |
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| 2007 |
Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell. 130: 77-88. PMID 17632057 DOI: 10.1016/J.Cell.2007.05.042 |
0.749 |
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| 2007 |
Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL. Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. Journal of Immunology (Baltimore, Md. : 1950). 179: 928-38. PMID 17617584 DOI: 10.4049/Jimmunol.179.2.928 |
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| 2007 |
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Jaenisch R, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/Nature06008 |
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| 2007 |
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature. 448: 318-24. PMID 17554336 DOI: 10.1038/Nature05944 |
0.689 |
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| 2007 |
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 1663-76. PMID 17477386 DOI: 10.1002/Dvdy.21176 |
0.358 |
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| 2007 |
Hansson MG, Helgesson G, Wessman R, Jaenisch R. Commentary: isolated stem cells--patentable as cultural artifacts? Stem Cells (Dayton, Ohio). 25: 1507-10. PMID 17347494 DOI: 10.1634/Stemcells.2006-0684 |
0.394 |
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| 2007 |
Giacometti E, Luikenhuis S, Beard C, Jaenisch R. Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proceedings of the National Academy of Sciences of the United States of America. 104: 1931-6. PMID 17267601 DOI: 10.1073/Pnas.0610593104 |
0.35 |
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| 2007 |
Hochedlinger K, Jaenisch R. On the cloning of animals from terminally differentiated cells. Nature Genetics. 39: 136-7; author reply . PMID 17262020 DOI: 10.1038/Ng0207-136 |
0.381 |
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| 2007 |
Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nature Genetics. 39: 380-5. PMID 17259983 DOI: 10.1038/Ng1969 |
0.363 |
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| 2007 |
Jaenisch R. An American scientist in Tehran Stem Cells. 1-1. DOI: 10.1038/Stemcells.2007.105 |
0.321 |
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| 2007 |
Boyer LA, Jaenisch R, Mitalipova M. Genetic and Epigenetic Analysis of Human Embryonic Stem Cell Human Embryonic Stem Cells: the Practical Handbook. 107-119. DOI: 10.1002/9780470511619.ch8 |
0.682 |
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| 2006 |
Eminli S, Jaenisch R, Hochedlinger K. Strategies to induce nuclear reprogramming. Ernst Schering Foundation Symposium Proceedings. 83-98. PMID 17939296 |
0.363 |
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| 2006 |
Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A. Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Molecular and Cellular Biology. 26: 7167-77. PMID 16980619 DOI: 10.1128/Mcb.00810-06 |
0.458 |
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| 2006 |
Boyer LA, Mathur D, Jaenisch R. Molecular control of pluripotency. Current Opinion in Genetics & Development. 16: 455-62. PMID 16920351 DOI: 10.1016/J.Gde.2006.08.009 |
0.74 |
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| 2006 |
Meissner A, Jaenisch R. Mammalian nuclear transfer. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2460-9. PMID 16881069 DOI: 10.1002/Dvdy.20915 |
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| 2006 |
Hochedlinger K, Jaenisch R. Nuclear reprogramming and pluripotency. Nature. 441: 1061-7. PMID 16810240 DOI: 10.1038/Nature04955 |
0.392 |
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| 2006 |
Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells (Dayton, Ohio). 24: 2007-13. PMID 16709876 DOI: 10.1634/Stemcells.2006-0050 |
0.35 |
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| 2006 |
Shimazu K, Zhao M, Sakata K, Akbarian S, Bates B, Jaenisch R, Lu B. NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learning & Memory (Cold Spring Harbor, N.Y.). 13: 307-15. PMID 16705139 DOI: 10.1101/Lm.76006 |
0.303 |
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| 2006 |
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041 |
0.81 |
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| 2006 |
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, ... ... Jaenisch R, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 125: 301-13. PMID 16630818 DOI: 10.1016/J.Cell.2006.02.043 |
0.777 |
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| 2006 |
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, ... Jaenisch R, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/Nature04733 |
0.835 |
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| 2006 |
Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. Suppression of intestinal neoplasia by deletion of Dnmt3b. Molecular and Cellular Biology. 26: 2976-83. PMID 16581773 DOI: 10.1128/Mcb.26.8.2976-2983.2006 |
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| 2006 |
Jaenisch R, Meissner A. Politically correct human embryonic stem cells? The New England Journal of Medicine. 354: 1208-9; author reply. PMID 16540629 DOI: 10.1056/Nejmc055530 |
0.378 |
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| 2006 |
Yang X, Eggan K, Seidel G, Jaenisch R, Melton D. A simple system of checks and balances to cut fraud. Nature. 439: 782. PMID 16482128 DOI: 10.1038/439782B |
0.488 |
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| 2006 |
Chang Q, Khare G, Dani V, Nelson S, Jaenisch R. The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron. 49: 341-8. PMID 16446138 DOI: 10.1016/J.Neuron.2005.12.027 |
0.323 |
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| 2006 |
Brambrink T, Hochedlinger K, Bell G, Jaenisch R. ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable. Proceedings of the National Academy of Sciences of the United States of America. 103: 933-8. PMID 16418286 DOI: 10.1073/Pnas.0510485103 |
0.476 |
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| 2006 |
Rios M, Lambe EK, Liu R, Teillon S, Liu J, Akbarian S, Roffler-Tarlov S, Jaenisch R, Aghajanian GK. Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. Journal of Neurobiology. 66: 408-20. PMID 16408297 DOI: 10.1002/Neu.20233 |
0.301 |
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| 2006 |
Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (New York, N.Y. : 2000). 44: 23-8. PMID 16400644 DOI: 10.1002/Gene.20180 |
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| 2006 |
Meissner A, Jaenisch R. Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature. 439: 212-5. PMID 16227971 DOI: 10.1038/Nature04257 |
0.402 |
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| 2006 |
Gemelli T, Berton O, Nelson ED, Perrotti LI, Jaenisch R, Monteggia LM. Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice. Biological Psychiatry. 59: 468-76. PMID 16199017 DOI: 10.1016/J.Biopsych.2005.07.025 |
0.329 |
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| 2005 |
Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM, Jaenisch R. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell. 8: 275-85. PMID 16226703 DOI: 10.1016/J.Ccr.2005.09.007 |
0.768 |
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| 2005 |
Meissner A, Gnirke A, Bell GW, Ramsahoye B, Lander ES, Jaenisch R. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Research. 33: 5868-77. PMID 16224102 DOI: 10.1093/Nar/Gki901 |
0.342 |
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| 2005 |
Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13580-5. PMID 16174748 DOI: 10.1073/Pnas.0506612102 |
0.726 |
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| 2005 |
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 122: 947-56. PMID 16153702 DOI: 10.1016/J.Cell.2005.08.020 |
0.763 |
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| 2005 |
Dani VS, Chang Q, Maffei A, Turrigiano GG, Jaenisch R, Nelson SB. Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. 102: 12560-5. PMID 16116096 DOI: 10.1073/Pnas.0506071102 |
0.317 |
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| 2005 |
Jaenisch R, Hochedlinger K, Eggan K. Nuclear cloning, epigenetic reprogramming and cellular differentiation. Novartis Foundation Symposium. 265: 107-18; discussion 1. PMID 16050253 |
0.638 |
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| 2005 |
Houbaviy HB, Dennis L, Jaenisch R, Sharp PA. Characterization of a highly variable eutherian microRNA gene. Rna (New York, N.Y.). 11: 1245-57. PMID 15987809 DOI: 10.1261/Rna.2890305 |
0.496 |
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| 2005 |
Hochedlinger K, Yamada Y, Beard C, Jaenisch R. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell. 121: 465-77. PMID 15882627 DOI: 10.1016/J.Cell.2005.02.018 |
0.44 |
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| 2005 |
Lyckman AW, Fan G, Rios M, Jaenisch R, Sur M. Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Visual Neuroscience. 22: 27-36. PMID 15842738 DOI: 10.1017/S095252380522103X |
0.484 |
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| 2005 |
Ma Y, Jacobs SB, Jackson-Grusby L, Mastrangelo MA, Torres-Betancourt JA, Jaenisch R, Rasmussen TP. DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. Journal of Cell Science. 118: 1607-16. PMID 15784683 DOI: 10.1242/Jcs.02291 |
0.747 |
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| 2005 |
Koralov SB, Novobrantseva TI, Hochedlinger K, Jaenisch R, Rajewsky K. Direct in vivo VH to JH rearrangement violating the 12/23 rule. The Journal of Experimental Medicine. 201: 341-8. PMID 15699070 DOI: 10.1084/Jem.20041577 |
0.332 |
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| 2005 |
Gribnau J, Luikenhuis S, Hochedlinger K, Monkhorst K, Jaenisch R. X chromosome choice occurs independently of asynchronous replication timing. The Journal of Cell Biology. 168: 365-73. PMID 15668296 DOI: 10.1083/Jcb.200405117 |
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| 2004 |
Jaenisch R, Hochedlinger K, Blelloch R, Yamada Y, Baldwin K, Eggan K. Nuclear cloning, epigenetic reprogramming, and cellular differentiation. Cold Spring Harbor Symposia On Quantitative Biology. 69: 19-27. PMID 16117629 DOI: 10.1002/0470091452.Ch9 |
0.674 |
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| 2004 |
Jaenisch R. Human cloning - the science and ethics of nuclear transplantation. The New England Journal of Medicine. 351: 2787-91. PMID 15625328 DOI: 10.1056/Nejmp048304 |
0.341 |
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| 2004 |
Plath K, Talbot D, Hamer KM, Otte AP, Yang TP, Jaenisch R, Panning B. Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. The Journal of Cell Biology. 167: 1025-35. PMID 15596546 DOI: 10.1083/Jcb.200409026 |
0.794 |
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| 2004 |
Mihich E, Jaenisch R. Sixteenth Annual Pezcoller Symposium: stem cells and epigenesis in cancer. Cancer Research. 64: 8474-7. PMID 15548721 DOI: 10.1158/0008-5472.Can-04-2625 |
0.409 |
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| 2004 |
Wang Z, Jaenisch R. At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation. Developmental Biology. 275: 192-201. PMID 15464582 DOI: 10.1016/J.Ydbio.2004.06.026 |
0.423 |
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| 2004 |
Begum NA, Kinoshita K, Kakazu N, Muramatsu M, Nagaoka H, Shinkura R, Biniszkiewicz D, Boyer LA, Jaenisch R, Honjo T. Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science (New York, N.Y.). 305: 1160-3. PMID 15326357 DOI: 10.1126/Science.1098444 |
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| 2004 |
Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R. Nuclear cloning of embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 13985-90. PMID 15306687 DOI: 10.1073/Pnas.0405015101 |
0.641 |
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| 2004 |
Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, Chin L, Jaenisch R. Reprogramming of a melanoma genome by nuclear transplantation. Genes & Development. 18: 1875-85. PMID 15289459 DOI: 10.1101/Gad.1213504 |
0.4 |
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| 2004 |
Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. Cre-lox-regulated conditional RNA interference from transgenes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10380-5. PMID 15240889 DOI: 10.1073/Pnas.0403954101 |
0.504 |
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| 2004 |
Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/Jci20926 |
0.353 |
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| 2004 |
Hochedlinger K, Rideout WM, Kyba M, Daley GQ, Blelloch R, Jaenisch R. Nuclear transplantation, embryonic stem cells and the potential for cell therapy. The Hematology Journal : the Official Journal of the European Haematology Association / Eha. 5: S114-7. PMID 15190291 DOI: 10.1038/Sj.Thj.6200435 |
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| 2004 |
Luikenhuis S, Giacometti E, Beard CF, Jaenisch R. Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 6033-8. PMID 15069197 DOI: 10.1073/Pnas.0401626101 |
0.34 |
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| 2004 |
Natoli TA, Alberta JA, Bortvin A, Taglienti ME, Menke DB, Loring J, Jaenisch R, Page DC, Housman DE, Kreidberg JA. Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis. Developmental Biology. 268: 429-40. PMID 15063178 DOI: 10.1016/J.Ydbio.2003.12.033 |
0.701 |
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| 2004 |
Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, Chess A, Axel R, Jaenisch R. Mice cloned from olfactory sensory neurons. Nature. 428: 44-9. PMID 14990966 DOI: 10.1038/Nature02375 |
0.599 |
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| 2003 |
Eggan K, Jaenisch R. Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation. Seminars in Cell & Developmental Biology. 14: 349-58. PMID 15015742 DOI: 10.1016/J.Semcdb.2003.09.012 |
0.597 |
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| 2003 |
Eggan K, Jaenisch R. Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation. Methods in Enzymology. 365: 25-39. PMID 14696335 DOI: 10.1016/S0076-6879(03)65002-0 |
0.645 |
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| 2003 |
Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (New York, N.Y.). 302: 885-9. PMID 14593183 DOI: 10.1126/Science.1086446 |
0.345 |
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| 2003 |
Hochedlinger K, Jaenisch R. Nuclear transplantation, embryonic stem cells, and the potential for cell therapy. The New England Journal of Medicine. 349: 275-86. PMID 12867612 DOI: 10.1056/Nejmra035397 |
0.424 |
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| 2003 |
Schwenk F, Zevnik B, Brüning J, Röhl M, Willuweit A, Rode A, Hennek T, Kauselmann G, Jaenisch R, Kühn R. Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics. Molecular and Cellular Biology. 23: 3982-9. PMID 12748299 DOI: 10.1128/Mcb.23.11.3982-3989.2003 |
0.443 |
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| 2003 |
Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940 |
0.417 |
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| 2003 |
Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R. Induction of tumors in mice by genomic hypomethylation. Science (New York, N.Y.). 300: 489-92. PMID 12702876 DOI: 10.1126/Science.1083558 |
0.736 |
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| 2003 |
Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science (New York, N.Y.). 300: 455. PMID 12702868 DOI: 10.1126/Science.1083557 |
0.362 |
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| 2003 |
Gribnau J, Hochedlinger K, Hata K, Li E, Jaenisch R. Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization. Genes & Development. 17: 759-73. PMID 12651894 DOI: 10.1101/Gad.1059603 |
0.411 |
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| 2003 |
Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 112: 645-57. PMID 12628185 DOI: 10.1016/S0092-8674(03)00154-5 |
0.591 |
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| 2003 |
Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R. Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development (Cambridge, England). 130: 1673-80. PMID 12620990 DOI: 10.1242/Dev.00366 |
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| 2003 |
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature Genetics. 33: 245-54. PMID 12610534 DOI: 10.1038/Ng1089 |
0.392 |
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| 2003 |
Seibler J, Zevnik B, Küter-Luks B, Andreas S, Kern H, Hennek T, Rode A, Heimann C, Faust N, Kauselmann G, Schoor M, Jaenisch R, Rajewsky K, Kühn R, Schwenk F. Rapid generation of inducible mouse mutants. Nucleic Acids Research. 31: e12. PMID 12582257 DOI: 10.1093/Nar/Gng012 |
0.397 |
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| 2003 |
Endres M, Fan G, Hirt L, Jaenisch R. Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 150-3. PMID 12571446 DOI: 10.1097/01.Wcb.0000043949.67811.C6 |
0.481 |
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| 2003 |
Fan G, Jaenisch R, Kucera J. Corrigendum to “a role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception” Neuroscience. 118: 879. DOI: 10.1016/S0306-4522(02)00914-4 |
0.43 |
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| 2003 |
Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. Erratum: HIF-1α is essential for myeloid cell-mediated inflammation (Cell 112:5 (648)) Cell. 113. DOI: 10.1016/S0092-8674(03)00311-8 |
0.617 |
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| 2002 |
Jaenisch R, Eggan K, Humpherys D, Rideout W, Hochedlinger K. Nuclear cloning, stem cells, and genomic reprogramming. Cloning and Stem Cells. 4: 389-396. PMID 12630413 DOI: 10.1089/153623002321025069 |
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| 2002 |
Hochedlinger K, Jaenisch R. Nuclear transplantation: lessons from frogs and mice. Current Opinion in Cell Biology. 14: 741-8. PMID 12473349 DOI: 10.1016/S0955-0674(02)00380-0 |
0.44 |
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| 2002 |
McCarrey JR, Watson C, Atencio J, Ostermeier GC, Marahrens Y, Jaenisch R, Krawetz SA. X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis (New York, N.Y. : 2000). 34: 257-66. PMID 12434336 DOI: 10.1002/Gene.10163 |
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| 2002 |
Tudor M, Akbarian S, Chen RZ, Jaenisch R. Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proceedings of the National Academy of Sciences of the United States of America. 99: 15536-41. PMID 12432090 DOI: 10.1073/Pnas.242566899 |
0.385 |
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| 2002 |
Turner JM, Mahadevaiah SK, Elliott DJ, Garchon HJ, Pehrson JR, Jaenisch R, Burgoyne PS. Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. Journal of Cell Science. 115: 4097-105. PMID 12356914 DOI: 10.1242/Jcs.00111 |
0.356 |
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| 2002 |
Humpherys D, Eggan K, Akutsu H, Friedman A, Hochedlinger K, Yanagimachi R, Lander ES, Golub TR, Jaenisch R. Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proceedings of the National Academy of Sciences of the United States of America. 99: 12889-94. PMID 12235366 DOI: 10.1073/Pnas.192433399 |
0.644 |
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| 2002 |
Akbarian S, Rios M, Liu RJ, Gold SJ, Fong HF, Zeiler S, Coppola V, Tessarollo L, Jones KR, Nestler EJ, Aghajanian GK, Jaenisch R. Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4153-62. PMID 12019333 DOI: 10.1523/Jneurosci.22-10-04153.2002 |
0.302 |
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| 2002 |
Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R. Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nature Biotechnology. 20: 455-9. PMID 11981557 DOI: 10.1038/Nbt0502-455 |
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| 2002 |
Rideout WM, Hochedlinger K, Kyba M, Daley GQ, Jaenisch R. Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell. 109: 17-27. PMID 11955443 DOI: 10.1016/S0092-8674(02)00681-5 |
0.425 |
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| 2002 |
Biniszkiewicz D, Gribnau J, Ramsahoye B, Gaudet F, Eggan K, Humpherys D, Mastrangelo MA, Jun Z, Walter J, Jaenisch R. Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Molecular and Cellular Biology. 22: 2124-35. PMID 11884600 DOI: 10.1128/Mcb.22.7.2124-2135.2002 |
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| 2002 |
Hochedlinger K, Jaenisch R. Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature. 415: 1035-8. PMID 11875572 DOI: 10.1038/Nature718 |
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| 2002 |
Possemato R, Eggan K, Moeller BJ, Jaenisch R, Jackson-Grusby L. Flp recombinase regulated lacZ expression at the ROSA26 locus. Genesis (New York, N.Y. : 2000). 32: 184-6. PMID 11857816 DOI: 10.1002/Gene.10039 |
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| 2002 |
Wutz A, Rasmussen TP, Jaenisch R. Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nature Genetics. 30: 167-74. PMID 11780141 DOI: 10.1038/Ng820 |
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| 2002 |
Fan G, Copray S, Huang EJ, Jones K, Yan Q, Walro J, Jaenisch R, Kucera J. Formation of a full complement of cranial proprioceptors requires multiple neurotrophins Developmental Dynamics. 225: 602-602. DOI: 10.1002/Dvdy.10197 |
0.442 |
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| 2001 |
Rasmussen TP, Wutz AP, Pehrson JR, Jaenisch RR. Expression of Xist RNA is sufficient to initiate macrochromatin body formation. Chromosoma. 110: 411-20. PMID 11734999 DOI: 10.1007/S004120100158 |
0.371 |
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| 2001 |
Fan G, Siniaia M, Poon CS, Jaenisch R. Effect of DNA hypomethylation on neural control of respiration: a genetic model. Advances in Experimental Medicine and Biology. 499: 195-200. PMID 11729877 DOI: 10.1007/978-1-4615-1375-9_30 |
0.532 |
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| 2001 |
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Pérez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, ... Jaenisch R, et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 15: 763-74. PMID 11728338 DOI: 10.1016/S1074-7613(01)00227-8 |
0.44 |
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| 2001 |
Endres M, Fan G, Meisel A, Dirnagl U, Jaenisch R. Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons. Neuroreport. 12: 3763-6. PMID 11726790 DOI: 10.1097/00001756-200112040-00032 |
0.515 |
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| 2001 |
Luikenhuis S, Wutz A, Jaenisch R. Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells. Molecular and Cellular Biology. 21: 8512-20. PMID 11713286 DOI: 10.1128/Mcb.21.24.8512-8520.2001 |
0.428 |
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| 2001 |
Akbarian S, Chen RZ, Gribnau J, Rasmussen TP, Fong H, Jaenisch R, Jones EG. Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex. Neurobiology of Disease. 8: 784-91. PMID 11592848 DOI: 10.1006/Nbdi.2001.0420 |
0.304 |
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| 2001 |
Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Molecular Endocrinology (Baltimore, Md.). 15: 1748-57. PMID 11579207 DOI: 10.1210/Mend.15.10.0706 |
0.464 |
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| 2001 |
Akbarian S, Bates B, Liu RJ, Skirboll SL, Pejchal T, Coppola V, Sun LD, Fan G, Kucera J, Wilson MA, Tessarollo L, Kosofsky BE, Taylor JR, Bothwell M, Nestler EJ, ... ... Jaenisch R, et al. Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal. Molecular Psychiatry. 6: 593-604. PMID 11526474 DOI: 10.1038/Sj.Mp.4000897 |
0.483 |
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| 2001 |
Rideout WM, Eggan K, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science (New York, N.Y.). 293: 1093-8. PMID 11498580 DOI: 10.1126/Science.1063206 |
0.65 |
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| 2001 |
Humpherys D, Eggan K, Akutsu H, Hochedlinger K, Rideout WM, Biniszkiewicz D, Yanagimachi R, Jaenisch R. Epigenetic instability in ES cells and cloned mice. Science (New York, N.Y.). 293: 95-7. PMID 11441181 DOI: 10.1126/Science.1061402 |
0.661 |
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| 2001 |
Csankovszki G, Nagy A, Jaenisch R. Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. The Journal of Cell Biology. 153: 773-84. PMID 11352938 DOI: 10.1083/Jcb.153.4.773 |
0.377 |
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| 2001 |
Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM, Yanagimachi R, Jaenisch R. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proceedings of the National Academy of Sciences of the United States of America. 98: 6209-14. PMID 11331774 DOI: 10.1073/Pnas.101118898 |
0.803 |
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| 2001 |
Jaenisch R, Wilmut I. Developmental biology. Don't clone humans! Science (New York, N.Y.). 291: 2552. PMID 11286275 DOI: 10.1126/Science.1060463 |
0.347 |
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| 2001 |
Chen RZ, Akbarian S, Tudor M, Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nature Genetics. 27: 327-31. PMID 11242118 DOI: 10.1038/85906 |
0.38 |
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| 2001 |
Haase VH, Glickman JN, Socolovsky M, Jaenisch R. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 98: 1583-8. PMID 11171994 DOI: 10.1073/Pnas.98.4.1583 |
0.615 |
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| 2001 |
Fan G, Beard C, Chen RZ, Csankovszki G, Sun Y, Siniaia M, Biniszkiewicz D, Bates B, Lee PP, Kuhn R, Trumpp A, Poon C, Wilson CB, Jaenisch R. DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 788-97. PMID 11157065 DOI: 10.1523/Jneurosci.21-03-00788.2001 |
0.572 |
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| 2001 |
Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E, Jaenisch R. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nature Genetics. 27: 31-9. PMID 11137995 DOI: 10.1038/83730 |
0.764 |
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| 2000 |
Lyko F, Ramsahoye BH, Jaenisch R. DNA methylation in Drosophila melanogaster. Nature. 408: 538-40. PMID 11117732 DOI: 10.1038/35046205 |
0.329 |
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| 2000 |
Eggan K, Akutsu H, Hochedlinger K, Rideout W, Yanagimachi R, Jaenisch R. X-Chromosome inactivation in cloned mouse embryos. Science (New York, N.Y.). 290: 1578-81. PMID 11090356 DOI: 10.1126/Science.290.5496.1578 |
0.574 |
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| 2000 |
Cherry SR, Biniszkiewicz D, van Parijs L, Baltimore D, Jaenisch R. Retroviral expression in embryonic stem cells and hematopoietic stem cells. Molecular and Cellular Biology. 20: 7419-26. PMID 11003639 DOI: 10.1128/MCB.20.20.7419-7426.2000 |
0.527 |
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| 2000 |
Rasmussen TP, Mastrangelo MA, Eden A, Pehrson JR, Jaenisch R. Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation. The Journal of Cell Biology. 150: 1189-98. PMID 10974005 DOI: 10.1083/Jcb.150.5.1189 |
0.408 |
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| 2000 |
Lyko F, Whittaker AJ, Orr-Weaver TL, Jaenisch R. The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries. Mechanisms of Development. 95: 215-7. PMID 10906465 DOI: 10.1016/S0925-4773(00)00325-7 |
0.383 |
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| 2000 |
Wutz A, Jaenisch R. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Molecular Cell. 5: 695-705. PMID 10882105 DOI: 10.1016/S1097-2765(00)80248-8 |
0.451 |
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| 2000 |
Cherry SR, Beard C, Jaenisch R, Baltimore D. V(D)J recombination is not activated by demethylation of the kappa locus. Proceedings of the National Academy of Sciences of the United States of America. 97: 8467-72. PMID 10880575 DOI: 10.1073/Pnas.150218497 |
0.529 |
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| 2000 |
Fan G, Copray S, Huang EJ, Jones K, Yan Q, Walro J, Jaenisch R, Kucera J. Formation of a full complement of cranial proprioceptors requires multiple neurotrophins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 359-70. PMID 10842362 DOI: 10.1002/(Sici)1097-0177(200006)218:2<359::Aid-Dvdy9>3.0.Co;2-L |
0.501 |
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| 2000 |
Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proceedings of the National Academy of Sciences of the United States of America. 97: 5237-42. PMID 10805783 DOI: 10.1073/Pnas.97.10.5237 |
0.383 |
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| 2000 |
Endres M, Meisel A, Biniszkiewicz D, Namura S, Prass K, Ruscher K, Lipski A, Jaenisch R, Moskowitz MA, Dirnagl U. DNA methyltransferase contributes to delayed ischemic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3175-81. PMID 10777781 DOI: 10.1523/Jneurosci.20-09-03175.2000 |
0.341 |
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| 2000 |
Fan G, Egles C, Sun Y, Minichiello L, Renger JJ, Klein R, Liu G, Jaenisch R. Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature Neuroscience. 3: 350-7. PMID 10725924 DOI: 10.1038/73921 |
0.494 |
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| 2000 |
Rideout WM, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nature Genetics. 24: 109-10. PMID 10655052 DOI: 10.1038/72753 |
0.776 |
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| 2000 |
Endres M, Fan G, Hirt L, Fujii M, Matsushita K, Liu X, Jaenisch R, Moskowitz MA. Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 139-44. PMID 10616802 DOI: 10.1097/00004647-200001000-00018 |
0.472 |
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| 1999 |
Lyko F, Ramsahoye BH, Kashevsky H, Tudor M, Mastrangelo MA, Orr-Weaver TL, Jaenisch R. Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila. Nature Genetics. 23: 363-6. PMID 10545955 DOI: 10.1038/15551 |
0.375 |
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| 1999 |
Tudor M, Murray PJ, Onufryk C, Jaenisch R, Young RA. Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes & Development. 13: 2365-8. PMID 10500093 DOI: 10.1101/Gad.13.18.2365 |
0.534 |
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| 1999 |
Tanaka M, Puchyr M, Gertsenstein M, Harpal K, Jaenisch R, Rossant J, Nagy A. Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation. Mechanisms of Development. 87: 129-42. PMID 10495277 DOI: 10.1016/S0925-4773(99)00158-6 |
0.413 |
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| 1999 |
Rasmussen TP, Huang T, Mastrangelo MA, Loring J, Panning B, Jaenisch R. Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing. Nucleic Acids Research. 27: 3685-9. PMID 10471737 DOI: 10.1093/Nar/27.18.3685 |
0.739 |
|
| 1999 |
Sidow A, Bulotsky MS, Kerrebrock AW, Birren BW, Altshuler D, Jaenisch R, Johnson KR, Lander ES. A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nature Genetics. 23: 104-7. PMID 10471509 DOI: 10.1038/12709 |
0.337 |
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| 1999 |
Csankovszki G, Panning B, Bates B, Pehrson JR, Jaenisch R. Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nature Genetics. 22: 323-4. PMID 10431231 DOI: 10.1038/11887 |
0.685 |
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| 1999 |
Donovan MJ, Natoli TA, Sainio K, Amstutz A, Jaenisch R, Sariola H, Kreidberg JA. Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Developmental Genetics. 24: 252-62. PMID 10322633 DOI: 10.1002/(Sici)1520-6408(1999)24:3/4<252::Aid-Dvg8>3.0.Co;2-K |
0.683 |
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| 1999 |
Bates B, Rios M, Trumpp A, Chen C, Fan G, Bishop JM, Jaenisch R. Neurotrophin-3 is required for proper cerebellar development. Nature Neuroscience. 2: 115-7. PMID 10195193 DOI: 10.1038/5669 |
0.455 |
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| 1999 |
Fan G, Jaenisch R, Kucera J. A role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception. Neuroscience. 90: 259-68. PMID 10188952 DOI: 10.1016/S0306-4522(98)00432-1 |
0.496 |
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| 1998 |
Gaudet F, Talbot D, Leonhardt H, Jaenisch R. A short DNA methyltransferase isoform restores methylation in vivo. The Journal of Biological Chemistry. 273: 32725-9. PMID 9830015 DOI: 10.1074/Jbc.273.49.32725 |
0.499 |
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| 1998 |
Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature. 395: 89-93. PMID 9738504 DOI: 10.1038/25779 |
0.755 |
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| 1998 |
Jaenisch R, Beard C, Lee J, Marahrens Y, Panning B. Mammalian X chromosome inactivation. Novartis Foundation Symposium. 214: 200-9; discussion 20. PMID 9601019 DOI: 10.1002/9780470515501.Ch12 |
0.753 |
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| 1998 |
Panning B, Jaenisch R. RNA and the epigenetic regulation of X chromosome inactivation. Cell. 93: 305-8. PMID 9590161 DOI: 10.1016/S0092-8674(00)81155-1 |
0.707 |
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| 1998 |
Hormuzdi SG, Penttinen R, Jaenisch R, Bornstein P. A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene. Molecular and Cellular Biology. 18: 3368-75. PMID 9584177 DOI: 10.1128/Mcb.18.6.3368 |
0.396 |
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| 1998 |
Warnecke PM, Biniszkiewicz D, Jaenisch R, Frommer M, Clark SJ. Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene. Developmental Genetics. 22: 111-21. PMID 9581283 DOI: 10.1002/(Sici)1520-6408(1998)22:2<111::Aid-Dvg1>3.0.Co;2-9 |
0.398 |
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| 1998 |
Kucera J, Fan G, Walro J, Copray S, Tessarollo L, Jaenisch R. Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles. Neuroreport. 9: 905-9. PMID 9579688 DOI: 10.1097/00001756-199803300-00026 |
0.457 |
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| 1998 |
Marahrens Y, Loring J, Jaenisch R. Role of the Xist gene in X chromosome choosing. Cell. 92: 657-64. PMID 9506520 DOI: 10.1016/S0092-8674(00)81133-2 |
0.313 |
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| 1998 |
You Y, Bersgtram R, Klemm M, Nelson H, Jaenisch R, Schimenti J. Utility of C57BL/6J x 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to gamma radiation and microsatellite polymorphism. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 232-4. PMID 9501308 DOI: 10.1007/S003359900731 |
0.36 |
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| 1998 |
Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R, Wahl GM. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Current Biology : Cb. 8: 145-55. PMID 9443911 DOI: 10.1016/S0960-9822(98)70061-2 |
0.409 |
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| 1998 |
MOORE A, SCHEDL A, McINNES L, KREIDBERG J, JAENISCH R, HASTIE N. New Wilms' tumour suppressor gene (WT1) functions
revealed by YAC transgenic analysis Genetical Research. 72: 59-72. DOI: 10.1017/S001667239834330X |
0.58 |
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| 1997 |
Pradhan S, Talbot D, Sha M, Benner J, Hornstra L, Li E, Jaenisch R, Roberts RJ. Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase. Nucleic Acids Research. 25: 4666-73. PMID 9358180 DOI: 10.1093/Nar/25.22.4666 |
0.311 |
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| 1997 |
Sidow A, Bulotsky MS, Kerrebrock AW, Bronson RT, Daly MJ, Reeve MP, Hawkins TL, Birren BW, Jaenisch R, Lander ES. Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature. 389: 722-5. PMID 9338782 DOI: 10.1038/39587 |
0.347 |
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| 1997 |
Sabapathy K, Klemm M, Jaenisch R, Wagner EF. Regulation of ES cell differentiation by functional and conformational modulation of p53. The Embo Journal. 16: 6217-29. PMID 9321401 DOI: 10.1093/Emboj/16.20.6217 |
0.574 |
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| 1997 |
Panning B, Dausman J, Jaenisch R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell. 90: 907-16. PMID 9298902 DOI: 10.1016/S0092-8674(00)80355-4 |
0.72 |
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| 1997 |
Tucker KL, Wang Y, Dausman J, Jaenisch R. A transgenic mouse strain expressing four drug-selectable marker genes. Nucleic Acids Research. 25: 3745-6. PMID 9278500 DOI: 10.1093/Nar/25.18.3745 |
0.326 |
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| 1997 |
Jaenisch R. DNA methylation and imprinting: why bother? Trends in Genetics : Tig. 13: 323-9. PMID 9260519 DOI: 10.1016/S0168-9525(97)01180-3 |
0.363 |
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| 1997 |
Di Fruscio M, Weiher H, Vanderhyden BC, Imai T, Shiomi T, Hori TA, Jaenisch R, Gray DA. Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest. Molecular and Cellular Biology. 17: 4080-6. PMID 9199343 DOI: 10.1128/Mcb.17.7.4080 |
0.387 |
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| 1997 |
DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO. alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. The Journal of Cell Biology. 137: 729-42. PMID 9151677 DOI: 10.1083/Jcb.137.3.729 |
0.591 |
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| 1997 |
Liu X, Wu H, Loring J, Hormuzdi S, Disteche CM, Bornstein P, Jaenisch R. Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 85-91. PMID 9142498 DOI: 10.1002/(Sici)1097-0177(199705)209:1<85::Aid-Aja8>3.0.Co;2-T |
0.309 |
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| 1997 |
Lee JT, Jaenisch R. The (epi)genetic control of mammalian X-chromosome inactivation. Current Opinion in Genetics & Development. 7: 274-80. PMID 9115428 DOI: 10.1016/S0959-437X(97)80138-4 |
0.513 |
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| 1997 |
Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 94: 4681-5. PMID 9114051 DOI: 10.1073/Pnas.94.9.4681 |
0.8 |
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| 1997 |
Lee JT, Jaenisch R. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature. 386: 275-9. PMID 9069285 DOI: 10.1038/386275A0 |
0.528 |
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| 1997 |
You Y, Bergstrom R, Klemm M, Lederman B, Nelson H, Ticknor C, Jaenisch R, Schimenti J. Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nature Genetics. 15: 285-8. PMID 9054943 DOI: 10.1038/Ng0397-285 |
0.372 |
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| 1997 |
Liu X, Wu H, Byrne M, Krane S, Jaenisch R. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development. Proceedings of the National Academy of Sciences of the United States of America. 94: 1852-6. PMID 9050868 DOI: 10.1073/Pnas.94.5.1852 |
0.334 |
|
| 1997 |
Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R. Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes & Development. 11: 156-66. PMID 9009199 DOI: 10.1101/Gad.11.2.156 |
0.714 |
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| 1997 |
Iruela-Arispe ML, Vernon RB, Wu H, Jaenisch R, Sage EH. Type I collagen-deficient Mov-13 mice do not retain SPARC in the extracellular matrix: implications for fibroblast function. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 207: 171-83. PMID 8906420 DOI: 10.1002/(Sici)1097-0177(199610)207:2<171::Aid-Aja5>3.0.Co;2-E |
0.317 |
|
| 1996 |
Jackson-Grusby L, Jaenisch R. Experimental manipulation of genomic methylation. Seminars in Cancer Biology. 7: 261-8. PMID 9110403 DOI: 10.1006/Scbi.1996.0034 |
0.735 |
|
| 1996 |
Lee JT, Jaenisch R. A method for high efficiency YAC lipofection into murine embryonic stem cells. Nucleic Acids Research. 24: 5054-5. PMID 9016681 DOI: 10.1093/Nar/24.24.5054 |
0.599 |
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| 1996 |
Laird PW, Jaenisch R. The role of DNA methylation in cancer genetics and epigenetics Annual Review of Genetics. 30: 441-464. PMID 8982461 DOI: 10.1146/Annurev.Genet.30.1.441 |
0.659 |
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| 1996 |
Kreidberg JA, Donovan MJ, Goldstein SL, Rennke H, Shepherd K, Jones RC, Jaenisch R. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development (Cambridge, England). 122: 3537-47. PMID 8951069 |
0.574 |
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| 1996 |
Tucker KL, Talbot D, Lee MA, Leonhardt H, Jaenisch R. Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene Proceedings of the National Academy of Sciences of the United States of America. 93: 12920-12925. PMID 8917520 DOI: 10.1073/Pnas.93.23.12920 |
0.463 |
|
| 1996 |
Harbers K, Müller U, Grams A, Li E, Jaenisch R, Franz T. Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality. Proceedings of the National Academy of Sciences of the United States of America. 93: 12412-7. PMID 8901595 DOI: 10.1073/Pnas.93.22.12412 |
0.346 |
|
| 1996 |
Chun J, Jaenisch R. Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses Molecular and Cellular Neurosciences. 7: 304-321. PMID 8793865 DOI: 10.1006/Mcne.1996.0023 |
0.565 |
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| 1996 |
Panning B, Jaenisch R. DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes & Development. 10: 1991-2002. PMID 8769643 DOI: 10.1101/Gad.10.16.1991 |
0.753 |
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| 1996 |
Lee JT, Strauss WM, Dausman JA, Jaenisch R. A 450 kb transgene displays properties of the mammalian X-inactivation center. Cell. 86: 83-94. PMID 8689690 DOI: 10.1016/S0092-8674(00)80079-3 |
0.58 |
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| 1996 |
Gardner H, Kreidberg J, Koteliansky V, Jaenisch R. Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Developmental Biology. 175: 301-13. PMID 8626034 DOI: 10.1006/Dbio.1996.0116 |
0.641 |
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| 1996 |
Schorle H, Meier P, Buchert M, Jaenisch R, Mitchell PJ. Transcription factor AP-2 essential for cranial closure and craniofacial development Nature. 381: 235-238. PMID 8622765 DOI: 10.1038/381235A0 |
0.357 |
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| 1996 |
Tucker KL, Beard C, Dausmann J, Jackson-Grusby L, Laird PW, Lei H, Li E, Jaenisch R. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes & Development. 10: 1008-20. PMID 8608936 DOI: 10.1101/Gad.10.8.1008 |
0.828 |
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| 1996 |
Wang Y, Schnegelsberg PN, Dausman J, Jaenisch R. Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. Nature. 379: 823-5. PMID 8587605 DOI: 10.1038/379823A0 |
0.379 |
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| 1995 |
Ernfors P, Kucera J, Lee KF, Loring J, Jaenisch R. Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice. The International Journal of Developmental Biology. 39: 799-807. PMID 8645564 DOI: 10.1387/Ijdb.8645564 |
0.303 |
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| 1995 |
Kucera J, Fan G, Jaenisch R, Linnarsson S, Ernfors P. Dependence of developing group Ia afferents on neurotrophin-3. The Journal of Comparative Neurology. 363: 307-20. PMID 8642077 DOI: 10.1002/Cne.903630211 |
0.475 |
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| 1995 |
Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A. Functional analysis of activins during mammalian development. Nature. 374: 354-6. PMID 7885473 DOI: 10.1038/374354A0 |
0.708 |
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| 1995 |
Rudnicki MA, Jaenisch R. The MyoD family of transcription factors and skeletal myogenesis Bioessays. 17: 203-209. PMID 7748174 DOI: 10.1002/Bies.950170306 |
0.329 |
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| 1995 |
Beard C, Li E, Jaenisch R. Loss of methylation activates Xist in somatic but not in embryonic cells. Genes & Development. 9: 2325-34. PMID 7557385 DOI: 10.1101/Gad.9.19.2325 |
0.448 |
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| 1995 |
Wu H, Liu X, Jaenisch R, Lodish HF. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 83: 59-67. PMID 7553874 DOI: 10.1016/0092-8674(95)90234-1 |
0.305 |
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| 1995 |
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R. Suppression of intestinal neoplasia by DNA hypomethylation. Cell. 81: 197-205. PMID 7537636 DOI: 10.1016/0092-8674(95)90329-1 |
0.788 |
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| 1995 |
Jüttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proceedings of the National Academy of Sciences of the United States of America. 91: 11797-801. PMID 7527544 DOI: 10.1073/Pnas.91.25.11797 |
0.423 |
|
| 1994 |
Rudnicki MA, Schnegelsberg PN, Stead RH, Braun T, Arnold HH, Jaenisch R. MyoD or Myf-5 is required for the formation of skeletal muscle. Cell. 75: 1351-9. PMID 8269513 DOI: 10.1016/0092-8674(93)90621-V |
0.307 |
|
| 1994 |
Fässler R, Schnegelsberg PN, Dausman J, Shinya T, Muragaki Y, McCarthy MT, Olsen BR, Jaenisch R. Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 5070-4. PMID 8197187 DOI: 10.1073/Pnas.91.11.5070 |
0.505 |
|
| 1994 |
Wu H, Liu X, Jaenisch R. Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 2819-23. PMID 8146196 DOI: 10.1073/Pnas.91.7.2819 |
0.351 |
|
| 1994 |
Vassalli A, Matzuk MM, Gardner HA, Lee KF, Jaenisch R. Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. Genes & Development. 8: 414-27. PMID 8125256 DOI: 10.1101/Gad.8.4.414 |
0.723 |
|
| 1994 |
Li E, Beard C, Forster AC, Bestor TH, Jaenisch R. DNA methylation, genomic imprinting, and mammalian development. Cold Spring Harbor Symposia On Quantitative Biology. 58: 297-305. PMID 7956042 DOI: 10.1101/Sqb.1993.058.01.035 |
0.32 |
|
| 1994 |
Laird PW, Jaenisch R. DNA methylation and cancer Human Molecular Genetics. 3: 1487-1495. PMID 7849743 DOI: 10.1093/Hmg/3.Suppl_1.1487 |
0.677 |
|
| 1993 |
Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. WT-1 is required for early kidney development. Cell. 74: 679-91. PMID 8395349 DOI: 10.1016/0092-8674(93)90515-R |
0.652 |
|
| 1993 |
Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature. 366: 362-5. PMID 8247133 DOI: 10.1038/366362A0 |
0.385 |
|
| 1993 |
Strauss WM, Dausman J, Beard C, Johnson C, Lawrence JB, Jaenisch R. Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus. Science (New York, N.Y.). 259: 1904-7. PMID 8096090 DOI: 10.1126/Science.8096090 |
0.42 |
|
| 1993 |
Li E, Sucov HM, Lee KF, Evans RM, Jaenisch R. Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor gene Proceedings of the National Academy of Sciences of the United States of America. 90: 1590-1594. PMID 7679509 DOI: 10.1073/Pnas.90.4.1590 |
0.384 |
|
| 1993 |
Brenner DA, Veloz L, Jaenisch R, Alcorn JM. Stimulation of the collagen α1(I) endogenous gene and transgene in carbon tetrachloride–induced hepatic fibrosis Hepatology. 17: 287-292. DOI: 10.1002/Hep.1840170220 |
0.323 |
|
| 1992 |
Gridley T, Jaenisch R, Gendron-Maguire M. The murine Mov-34 gene: full-length cDNA and genomic organization. Genomics. 11: 501-7. PMID 1837787 DOI: 10.1016/0888-7543(91)90056-K |
0.341 |
|
| 1992 |
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 69: 915-26. PMID 1606615 DOI: 10.1016/0092-8674(92)90611-F |
0.438 |
|
| 1992 |
Braun T, Rudnicki MA, Arnold HH, Jaenisch R. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death. Cell. 71: 369-82. PMID 1423602 DOI: 10.1016/0092-8674(92)90507-9 |
0.318 |
|
| 1992 |
Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML. Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature. 360: 225-31. PMID 1359428 DOI: 10.1038/360225A0 |
0.574 |
|
| 1992 |
Correa I, Bix M, Liao NS, Zijlstra M, Jaenisch R, Raulet D. Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 89: 653-7. PMID 1346234 DOI: 10.1073/Pnas.89.2.653 |
0.315 |
|
| 1992 |
Rudnicki MA, Braun T, Hinuma S, Jaenisch R. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell. 71: 383-90. PMID 1330322 DOI: 10.1016/0092-8674(92)90508-A |
0.305 |
|
| 1992 |
Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV, Jaenisch R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69: 737-49. PMID 1317267 DOI: 10.1016/0092-8674(92)90286-L |
0.333 |
|
| 1992 |
Wu H, Fässler R, Schnieke A, Barker D, Lee KH, Chapman V, Francke U, Jaenisch R. An X-linked human collagen transgene escapes X inactivation in a subset of cells. Development (Cambridge, England). 116: 687-95. PMID 1289060 |
0.548 |
|
| 1992 |
Strauss W, Jaenisch R. Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes. The Embo Journal. 11: 417-422. DOI: 10.1002/J.1460-2075.1992.Tb05070.X |
0.37 |
|
| 1991 |
Van Wijnen AJ, Chi TK, Owen TA, Wright KL, Lian JB, Jaenisch R, Stein JL, Stein GS. Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 88: 2573-2577. PMID 2006193 DOI: 10.1073/Pnas.88.6.2573 |
0.31 |
|
| 1991 |
Bix M, Liao NS, Zijlstra M, Loring J, Jaenisch R, Raulet D. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature. 349: 329-31. PMID 1987491 DOI: 10.1038/349329A0 |
0.358 |
|
| 1991 |
Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 64: 189-200. PMID 1986864 DOI: 10.1016/0092-8674(91)90220-S |
0.523 |
|
| 1991 |
Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, Berns A. Simplified mammalian DNA isolation procedure Nucleic Acids Research. 19: 4293. PMID 1870982 DOI: 10.1093/Nar/19.15.4293 |
0.616 |
|
| 1991 |
Liao NS, Bix M, Zijlstra M, Jaenisch R, Raulet D. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science (New York, N.Y.). 253: 199-202. PMID 1853205 DOI: 10.1126/Science.1853205 |
0.33 |
|
| 1991 |
Petersen R, Sobel S, Wang CT, Jaenisch R, Barklis E. Cellular transcripts encoded at a locus which permits retrovirus expression in mouse embryonic cells. Gene. 101: 177-83. PMID 1711497 DOI: 10.1016/0378-1119(91)90409-5 |
0.306 |
|
| 1990 |
Zijlstra M, Li E, Sajjadi F, Subramani S, Jaenisch R. Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature. 342: 435-8. PMID 2685607 DOI: 10.1038/342435A0 |
0.342 |
|
| 1990 |
Harbers K, Francke U, Soriano P, Jaenisch R, Müller U. Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes. Cytogenetics and Cell Genetics. 53: 129-33. PMID 1973377 DOI: 10.1159/000132912 |
0.528 |
|
| 1990 |
Weiher H, Noda T, Gray DA, Sharpe AH, Jaenisch R. Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome Cell. 62: 425-434. PMID 1696177 DOI: 10.1016/0092-8674(90)90008-3 |
0.331 |
|
| 1989 |
Stuhlmann H, Jaenisch R, Mulligan RC. Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector. Journal of Virology. 63: 4857-65. PMID 2795720 DOI: 10.1128/Jvi.63.11.4857-4865.1989 |
0.333 |
|
| 1989 |
Compere SJ, Baldacci P, Sharpe AH, Thompson T, Land H, Jaenisch R. The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors Proceedings of the National Academy of Sciences of the United States of America. 86: 2224-2228. PMID 2648394 DOI: 10.1073/Pnas.86.7.2224 |
0.319 |
|
| 1989 |
Bateman JF, Mascara T, Cole WG, Stacey A, Jaenisch R. Collagen Protein Abnormalities Produced by Site-Directed Mutagenesis of the Proal(I) Gene Connective Tissue Research. 20: 205-212. PMID 2612152 DOI: 10.3109/03008208909023889 |
0.341 |
|
| 1989 |
Kratochwil K, von der Mark K, Kollar EJ, Jaenisch R, Mooslehner K, Schwarz M, Haase K, Gmachl I, Harbers K. Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner Cell. 57: 807-816. PMID 2541924 DOI: 10.1016/0092-8674(89)90795-2 |
0.376 |
|
| 1988 |
Stacey A, Bateman J, Choi T, Mascara T, Cole W, Jaenisch R. Perinatal lethal osteogenesis imperfecta in transgenic mice bearing an engineered mutant pro-alpha 1(I) collagen gene. Nature. 332: 131-6. PMID 2450280 DOI: 10.1038/332131A0 |
0.316 |
|
| 1987 |
Berleth T, Nobis P, Jaenisch R, Harbers K. Activation of endogenous retroviral genomes in Mov strains of mice. Journal of General Virology. 68: 2919-2923. PMID 3681267 DOI: 10.1099/0022-1317-68-11-2919 |
0.343 |
|
| 1987 |
Weiher H, Barklis E, Ostertag W, Jaenisch R. Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells. Journal of Virology. 61: 2742-6. PMID 3612950 DOI: 10.1128/Jvi.61.9.2742-2746.1987 |
0.403 |
|
| 1987 |
Stacey A, Mulligan R, Jaenisch R. Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells. Journal of Virology. 61: 2549-54. PMID 3599181 DOI: 10.1128/Jvi.61.8.2549-2554.1987 |
0.326 |
|
| 1987 |
Soriano P, Keitges EA, Schorderet DF, Harbers K, Gartler SM, Jaenisch R. High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proceedings of the National Academy of Sciences of the United States of America. 84: 7218-20. PMID 3478692 DOI: 10.1073/Pnas.84.20.7218 |
0.541 |
|
| 1987 |
Schnieke A, Dziadek M, Bateman J, Mascara T, Harbers K, Gelinas R, Jaenisch R. Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen. Proceedings of the National Academy of Sciences of the United States of America. 84: 764-8. PMID 3468512 DOI: 10.1073/Pnas.84.3.764 |
0.317 |
|
| 1987 |
Münke M, Harbers K, Jaenisch R, Francke U. Chromosomal mapping of four different integration sites of Moloney murine leukemia virus including the locus for alpha 1(I) collagen in mouse. Cytogenetics and Cell Genetics. 43: 140-9. PMID 3467899 DOI: 10.1159/000132312 |
0.343 |
|
| 1987 |
Soriano P, Gridley T, Jaenisch R. Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. Genes & Development. 1: 366-75. PMID 2824282 DOI: 10.1101/Gad.1.4.366 |
0.567 |
|
| 1987 |
Gridley T, Soriano P, Jaenisch R. Insertional mutagenesis in mice Trends in Genetics. 3: 162-166. DOI: 10.1016/0168-9525(87)90218-6 |
0.556 |
|
| 1986 |
Hartung S, Jaenisch R, Breindl M. Retrovirus insertion inactivates mouse alpha 1(I) collagen gene by blocking initiation of transcription. Nature. 320: 365-7. PMID 3960120 DOI: 10.1038/320365A0 |
0.371 |
|
| 1986 |
Barklis E, Mulligan RC, Jaenisch R. Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells. Cell. 47: 391-9. PMID 3768959 DOI: 10.1016/0092-8674(86)90596-9 |
0.395 |
|
| 1986 |
Harbers K, Soriano P, Müller U, Jaenisch R. High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse. Nature. 324: 682-5. PMID 3025741 DOI: 10.1038/324682A0 |
0.546 |
|
| 1986 |
Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318 DOI: 10.1126/Science.3024318 |
0.583 |
|
| 1986 |
Soriano P, Jaenisch R. Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages. Cell. 46: 19-29. PMID 3013418 DOI: 10.1016/0092-8674(86)90856-1 |
0.589 |
|
| 1985 |
Stuhlmann H, Cone R, Mulligan RC, Jaenisch R. Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector. Proceedings of the National Academy of Sciences of the United States of America. 81: 7151-5. PMID 6095271 DOI: 10.1073/Pnas.81.22.7151 |
0.375 |
|
| 1985 |
Jaenisch R. Mammalian neural crest cells participate in normal embryonic development on microinjection into post-implantation mouse embryos. Nature. 318: 181-3. PMID 4058595 DOI: 10.1038/318181A0 |
0.376 |
|
| 1985 |
Reik W, Weiher H, Jaenisch R. Replication-competent Moloney murine leukemia virus carrying a bacterial suppressor tRNA gene: selective cloning of proviral and flanking host sequences. Proceedings of the National Academy of Sciences of the United States of America. 82: 1141-5. PMID 3883352 DOI: 10.1073/Pnas.82.4.1141 |
0.353 |
|
| 1985 |
Jähner D, Jaenisch R. Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity. Nature. 315: 594-7. PMID 2989695 DOI: 10.1038/315594A0 |
0.38 |
|
| 1985 |
Jaenisch R, Schnieke A, Harbers K. Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues. Proceedings of the National Academy of Sciences of the United States of America. 82: 1451-5. PMID 2579397 DOI: 10.1073/Pnas.82.5.1451 |
0.326 |
|
| 1985 |
Jähner D, Haase K, Mulligan R, Jaenisch R. Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection. Proceedings of the National Academy of Sciences of the United States of America. 82: 6927-31. PMID 2413448 DOI: 10.1073/Pnas.82.20.6927 |
0.391 |
|
| 1984 |
Löhler J, Timpl R, Jaenisch R. Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death. Cell. 38: 597-607. PMID 6467375 DOI: 10.1016/0092-8674(84)90514-2 |
0.358 |
|
| 1984 |
Jaenisch R, Jähner D. Methylation, expression and chromosomal position of genes in mammals. Biochimica Et Biophysica Acta. 782: 1-9. PMID 6372865 DOI: 10.1016/0167-4781(84)90099-X |
0.342 |
|
| 1984 |
Harbers K, Kuehn M, Delius H, Jaenisch R. Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice. Proceedings of the National Academy of Sciences of the United States of America. 81: 1504-8. PMID 6324198 DOI: 10.1073/Pnas.81.5.1504 |
0.325 |
|
| 1984 |
Breindl M, Harbers K, Jaenisch R. Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure. Cell. 38: 9-16. PMID 6088079 DOI: 10.1016/0092-8674(84)90521-X |
0.374 |
|
| 1983 |
Jaenisch R, Harbers K, Jähner D, Stewart C, Stuhlmann H. DNA methylation, retroviruses, and embryogenesis. Journal of Cellular Biochemistry. 20: 331-6. PMID 7183678 DOI: 10.1002/Jcb.240200403 |
0.442 |
|
| 1983 |
Jaenisch R, Harbers K, Jähner D, Stewart C, Stuhlmann H. Expression of retroviruses during early mouse embryogenesis. Haematology and Blood Transfusion. 28: 270-4. PMID 6862303 DOI: 10.1007/978-3-642-68761-7_50 |
0.369 |
|
| 1983 |
Schnieke A, Stuhlmann H, Harbers K, Chumakov I, Jaenisch R. Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome. Journal of Virology. 45: 505-513. PMID 6834466 DOI: 10.1128/Jvi.45.2.505-513.1983 |
0.318 |
|
| 1983 |
Jaenisch R, Harbers K, Schnieke A, Löhler J, Chumakov I, Jähner D, Grotkopp D, Hoffmann E. Germline integration of moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death. Cell. 32: 209-16. PMID 6825169 DOI: 10.1016/0092-8674(83)90511-1 |
0.315 |
|
| 1983 |
Stewart C, Harbers K, Jähner D, Jaenisch R. X chromosome-linked transmission and expression of retroviral genomes microinjected into mouse zygotes. Science (New York, N.Y.). 221: 760-2. PMID 6683871 DOI: 10.1126/Science.6683871 |
0.342 |
|
| 1983 |
Jähner D, Stewart CL, Stuhlmann H, Harbers K, Jaenisch R. Retroviruses and embryogenesis: de novo methylation activity involved in gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 611-9. PMID 6574867 DOI: 10.1101/Sqb.1983.047.01.072 |
0.346 |
|
| 1983 |
Schnieke A, Harbers K, Jaenisch R. Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene. Nature. 304: 315-20. PMID 6308457 DOI: 10.1038/304315A0 |
0.373 |
|
| 1983 |
Breindl M, Kalthoff H, Jaenisch R. Transcription of cloned Moloney murine leukemia proviral DNA injected into Xenopus laevis oocytes. Nucleic Acids Research. 11: 3989-4006. PMID 6306570 DOI: 10.1093/Nar/11.12.3989 |
0.323 |
|
| 1983 |
Simon D, Stuhlmann H, Jähner D, Wagner H, Werner E, Jaenisch R. Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious. Nature. 304: 275-7. PMID 6306480 DOI: 10.1038/304275A0 |
0.38 |
|
| 1982 |
Simon I, Lohler J, Jaenisch R. Virus-specific transcription and translation in organs of BALB / Mo mice: Comparative study using quantitative hybridization, in Situ hybridization, and immunocytochemistry Virology. 120: 106-121. PMID 7101725 DOI: 10.1016/0042-6822(82)90010-1 |
0.351 |
|
| 1982 |
Stewart CL, Stuhlmann H, Jähner D, Jaenisch R. De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4098-102. PMID 6955793 DOI: 10.1073/Pnas.79.13.4098 |
0.411 |
|
| 1982 |
Harbers K, Schnieke A, Stuhlmann H, Jähner D, Jaenisch R. DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning. Proceedings of the National Academy of Sciences of the United States of America. 78: 7609-13. PMID 6950402 DOI: 10.1073/Pnas.78.12.7609 |
0.398 |
|
| 1982 |
Jähner D, Stuhlmann H, Stewart CL, Harbers K, Löhler J, Simon I, Jaenisch R. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature. 298: 623-8. PMID 6285203 DOI: 10.1038/298623A0 |
0.364 |
|
| 1982 |
Chumakov I, Stuhlmann H, Harbers K, Jaenisch R. Cloning of two genetically transmitted Moloney leukemia proviral genomes: correlation between biological activity of the cloned DNA and viral genome activation in the animal. Journal of Virology. 42: 1088-98. PMID 6284989 DOI: 10.1128/Jvi.42.3.1088-1098.1982 |
0.377 |
|
| 1982 |
Harbers K, Schnieke A, Stuhlmann H, Jaenisch R. Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes. Nucleic Acids Research. 10: 2521-37. PMID 6281733 DOI: 10.1093/Nar/10.8.2521 |
0.322 |
|
| 1982 |
Stuhlmann H, Jähner D, Jaenisch R. Infectivity and methylation of retroviral genomes is correlated with expression in the animal. Cell. 26: 221-32. PMID 6277495 DOI: 10.1016/0092-8674(81)90305-6 |
0.405 |
|
| 1982 |
Fiedler W, Nobis P, Jähner D, Jaenisch R. Differentiation and virus expression in BALB/Mo mice: endogenous Moloney leukemia virus is not activated in hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 1874-8. PMID 6123114 DOI: 10.1073/Pnas.79.6.1874 |
0.382 |
|
| 1981 |
Jähner D, Jaenisch R. Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation. Nature. 287: 456-8. PMID 7432471 DOI: 10.1038/287456A0 |
0.324 |
|
| 1981 |
Jaenisch R, Jähner D, Nobis P, Simon I, Löhler J, Harbers K, Grotkopp D. Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell. 24: 519-29. PMID 7237558 DOI: 10.1016/0092-8674(81)90343-3 |
0.316 |
|
| 1981 |
Harbers K, Jähner D, Jaenisch R. Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal. Nature. 293: 540-2. PMID 7197324 DOI: 10.1038/293540A0 |
0.336 |
|
| 1980 |
Breindl M, Bacheler L, Fan H, Jaenisch R. Chromatin conformation of integrated Moloney leukemia virus DNA sequences in tissues of BALB/Mo mice and in virus-infected cell lines. Journal of Virology. 34: 373-382. PMID 7373714 DOI: 10.1128/Jvi.34.2.373-382.1980 |
0.351 |
|
| 1980 |
Jaenisch R. Retroviruses and embryogenesis: microinjection of Moloney leukemia virus into midgestation mouse embryos. Cell. 19: 181-8. PMID 7357600 DOI: 10.1016/0092-8674(80)90399-2 |
0.315 |
|
| 1980 |
Jähner D, Stuhlmann H, Jaenisch R. Conformation of free and of integrated Moloney leukemia virus proviral DNA in preleukemic and leukemic BALB/Mo mice. Virology. 101: 111-23. PMID 7355573 DOI: 10.1016/0042-6822(80)90488-2 |
0.361 |
|
| 1980 |
Nobis P, Jaenisch R. Passive immunotherapy prevents expression of endogenous Moloney virus and amplification of proviral DNA in BALB/Mo mice. Proceedings of the National Academy of Sciences of the United States of America. 77: 3677-81. PMID 6251475 DOI: 10.1073/Pnas.77.6.3677 |
0.315 |
|
| 1980 |
Doehmer J, Breindl M, Willecke K, Jaenisch R. Genetic transmission of Moloney leukemia virus: mapping of the chromosomal integration site. Haematology and Blood Transfusion. 23: 561-8. PMID 544367 DOI: 10.1007/978-3-642-67057-2_72 |
0.332 |
|
| 1980 |
van der Putten H, Terwindt E, Berns A, Jaenisch R. The integration sites of endogenous and exogenous Moloney murine leukemia virus. Cell. 18: 109-16. PMID 509516 DOI: 10.1016/0092-8674(79)90359-3 |
0.336 |
|
| 1980 |
Jaenisch R, Hoffmann E. Transcription of endogenous C-type viruses in resting and proliferating tissues of BALB/Mo mice. Virology. 98: 289-97. PMID 228474 DOI: 10.1016/0042-6822(79)90552-X |
0.323 |
|
| 1979 |
Jaenisch R. Moloney leukemia virus gene expression and gene amplification in preleukemic and leukemic BALB/Mo mice. Virology. 93: 80-90. PMID 571169 DOI: 10.1016/0042-6822(79)90277-0 |
0.35 |
|
| 1979 |
Breindl M, Jaenisch R. Conformation of Moloney murine leukaemia proviral sequences in chromatin from leukaemic and nonleukaemic cells. Nature. 277: 320-2. PMID 570252 DOI: 10.1038/277320A0 |
0.397 |
|
| 1979 |
Breindl M, Doehmer J, Willecke K, Dausman J, Jaenisch R. Germ line integration of Moloney leukemia virus: identification of the chromosomal integration site. Proceedings of the National Academy of Sciences of the United States of America. 76: 1938-42. PMID 287034 DOI: 10.1073/Pnas.76.4.1938 |
0.334 |
|
| 1976 |
Jaenisch R. Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus. Proceedings of the National Academy of Sciences of the United States of America. 73: 1260-4. PMID 1063407 DOI: 10.1073/Pnas.73.4.1260 |
0.301 |
|
| 1974 |
Jaenisch R, Mintz B. Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Proceedings of the National Academy of Sciences of the United States of America. 71: 1250-4. PMID 4364530 DOI: 10.1073/Pnas.71.4.1250 |
0.552 |
|
| 1973 |
Jaenisch R, Levine AJ. DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers. Journal of Molecular Biology. 73: 199-212. PMID 4347738 |
0.394 |
|
| 1972 |
Jaenisch R, Levine AJ. DNA replication in SV40-infected cells. VI. The effect of cycloheximide on the formation of SV40 oligomeric DNA. Virology. 48: 373-9. PMID 4337027 |
0.383 |
|
| 1972 |
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