Mattheos A. G. Koffas - Publications

Affiliations: 
2002-2011 Chemical and Biological Engineering State University of New York, Buffalo, Buffalo, NY, United States 
 2011- Chemical and Biological Engineering Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Chemical Engineering, Microbiology Biology, Pharmaceutical Chemistry
Website:
https://faculty.rpi.edu/mattheos-koffas

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Connor A, Zha RH, Koffas M. Production and secretion of recombinant spider silk in Bacillus megaterium. Microbial Cell Factories. 23: 35. PMID 38279170 DOI: 10.1186/s12934-024-02304-5  0.33
2023 Paliya BS, Sharma VK, Tuohy MG, Singh HB, Koffas M, Benhida R, Tiwari BK, Kalaskar DM, Singh BN, Gupta VK. Bacterial glycobiotechnology: A biosynthetic route for the production of biopharmaceutical glycans. Biotechnology Advances. 108180. PMID 37236328 DOI: 10.1016/j.biotechadv.2023.108180  0.419
2023 Xiao Z, Connor AJ, Worland AM, Tang YJ, Zha RH, Koffas M. Silk fibroin production in Escherichia coli is limited by a positive feedback loop between metabolic burden and toxicity stress. Metabolic Engineering. PMID 37024071 DOI: 10.1016/j.ymben.2023.03.011  0.395
2023 Jeandet P, Uddin MS, Clément C, Aziz A, Jacquard C, Khan H, Shah MA, Barka EA, Koffas M, Nabavi SM, Sobarzo-Sánchez E, Renault JH. Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems. Natural Product Reports. PMID 36880302 DOI: 10.1039/d2np00073c  0.362
2023 Connor A, Wigham C, Bai Y, Rai M, Nassif S, Koffas M, Zha RH. Novel insights into construct toxicity, strain optimization, and primary sequence design for producing recombinant silk fibroin and elastin-like peptide in . Metabolic Engineering Communications. 16: e00219. PMID 36825067 DOI: 10.1016/j.mec.2023.e00219  0.329
2022 Zha J, Zhao Z, Xiao Z, Eng T, Mukhopadhyay A, Koffas MA, Tang YJ. Biosystem design of Corynebacterium glutamicum for bioproduction. Current Opinion in Biotechnology. 79: 102870. PMID 36549106 DOI: 10.1016/j.copbio.2022.102870  0.341
2022 Akdemir H, Liu Y, Zhuang L, Zhang H, Koffas MA. Utilization of microbial cocultures for converting mixed substrates to valuable bioproducts. Current Opinion in Microbiology. 68: 102157. PMID 35644063 DOI: 10.1016/j.mib.2022.102157  0.323
2021 Wong M, Badri A, Gasparis C, Belfort G, Koffas M. Modular optimization in metabolic engineering. Critical Reviews in Biochemistry and Molecular Biology. 1-16. PMID 34180323 DOI: 10.1080/10409238.2021.1937928  0.308
2021 Connor AJ, Zha RH, Koffas M. Bioproduction of biomacromolecules for antiviral applications. Current Opinion in Biotechnology. 69: 263-272. PMID 33667798 DOI: 10.1016/j.copbio.2021.01.022  0.347
2020 Jeandet P, Vannozzi A, Sobarzo-Sánchez E, Uddin MS, Bru R, Martínez-Márquez A, Clément C, Cordelier S, Manayi A, Nabavi SF, Rasekhian M, El-Saber Batiha G, Khan H, Morkunas I, Belwal T, ... ... Koffas M, et al. Phytostilbenes as agrochemicals: biosynthesis, bioactivity, metabolic engineering and biotechnology. Natural Product Reports. PMID 33351014 DOI: 10.1039/d0np00030b  0.36
2020 Awofiranye AE, Baytas SN, Xia K, Badri A, He W, Varki A, Koffas M, Linhardt RJ. N-glycolyl chondroitin synthesis using metabolically engineered E. coli. Amb Express. 10: 144. PMID 32803432 DOI: 10.1186/S13568-020-01084-6  0.4
2020 Schilling C, Badri A, Sieber V, Koffas M, Schmid J. Metabolic engineering for production of functional polysaccharides. Current Opinion in Biotechnology. 66: 44-51. PMID 32673945 DOI: 10.1016/J.Copbio.2020.06.010  0.503
2020 Marsafari M, Ma J, Koffas M, Xu P. Genetically-encoded biosensors for analyzing and controlling cellular process in yeast. Current Opinion in Biotechnology. 64: 175-182. PMID 32563963 DOI: 10.1016/J.Copbio.2020.04.006  0.362
2020 Xu P, Marsafari M, Zha J, Koffas M. Microbial Coculture for Flavonoid Synthesis. Trends in Biotechnology. 38: 686-688. PMID 32497514 DOI: 10.1016/J.Tibtech.2020.01.008  0.47
2020 Marsafari M, Samizadeh H, Rabiei B, Mehrabi A, Koffas M, Xu P. Biotechnological Production of Flavonoids: An Update on Plant Metabolic Engineering, Microbial Host Selection and Genetically Encoded Biosensors. Biotechnology Journal. e1900432. PMID 32267085 DOI: 10.1002/Biot.201900432  0.513
2020 Zha J, Wu X, Koffas MA. Making brilliant colors by microorganisms. Current Opinion in Biotechnology. 61: 135-141. PMID 31927454 DOI: 10.1016/J.Copbio.2019.12.020  0.513
2020 Wu X, Zha J, Koffas MA. Microbial production of bioactive chemicals for human health Current Opinion in Food Science. 32: 9-16. DOI: 10.1016/J.Cofs.2019.12.007  0.427
2019 Jawed K, Yazdani SS, Koffas MA. Advances in the development and application of microbial consortia for metabolic engineering. Metabolic Engineering Communications. 9. PMID 31720211 DOI: 10.1016/J.Mec.2019.E00095  0.507
2019 Jeandet P, Sobarzo-Sánchez E, Silva AS, Clément C, Nabavi SF, Battino M, Rasekhian M, Belwal T, Habtemariam S, Koffas M, Nabavi SM. Whole-cell biocatalytic, enzymatic and green chemistry methods for the production of resveratrol and its derivatives. Biotechnology Advances. 107461. PMID 31678221 DOI: 10.1016/J.Biotechadv.2019.107461  0.491
2019 Dhakal D, Kim ES, Koffas M. Editorial: Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines. Frontiers in Microbiology. 10: 2307. PMID 31649647 DOI: 10.3389/Fmicb.2019.02307  0.434
2019 Wang R, Zhao S, Wang Z, Koffas MA. Recent advances in modular co-culture engineering for synthesis of natural products. Current Opinion in Biotechnology. 62: 65-71. PMID 31605875 DOI: 10.1016/J.Copbio.2019.09.004  0.503
2019 Wong M, Zha J, Sorci M, Gasparis C, Belfort G, Koffas M. Cell-free production of isobutanol: A completely immobilized system. Bioresource Technology. 294: 122104. PMID 31542497 DOI: 10.1016/J.Biortech.2019.122104  0.427
2019 Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ. Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei. Glycobiology. PMID 31143933 DOI: 10.1093/Glycob/Cwz039  0.321
2019 Singh BN, Raghubanshi AS, Koffas M, Gupta VK. Microbial engineering biotechnologies. Biotechnology Advances. PMID 31095968 DOI: 10.1016/J.Biotechadv.2019.05.005  0.347
2019 Roell GW, Zha J, Carr RR, Koffas MA, Fong SS, Tang YJ. Engineering microbial consortia by division of labor. Microbial Cell Factories. 18: 35. PMID 30736778 DOI: 10.1186/S12934-019-1083-3  0.463
2019 Sarnaik A, Abernathy MH, Han X, Ouyang Y, Xia K, Chen Y, Cress B, Zhang F, Lali A, Pandit R, Linhardt RJ, Tang YJ, Koffas MA. Metabolic engineering of cyanobacteria for photoautotrophic production of heparosan, a pharmaceutical precursor of heparin Algal Research. 37: 57-63. DOI: 10.1016/J.Algal.2018.11.010  0.38
2018 Morrison C, Heitmann E, Armiger W, Dodds D, Koffas M. Electrochemical Bioreactor Technology for Biocatalysis and Microbial Electrosynthesis. Advances in Applied Microbiology. 105: 51-86. PMID 30342723 DOI: 10.1016/Bs.Aambs.2018.07.001  0.417
2018 Williams A, Linhardt RJ, Koffas MA. Metabolic engineering of capsular polysaccharides Emerging Topics in Life Sciences. 2: 337-348. DOI: 10.1042/ETLS20180003  0.397
2017 Badri A, Williams A, Linhardt RJ, Koffas MA. The road to animal-free glycosaminoglycan production: current efforts and bottlenecks. Current Opinion in Biotechnology. 53: 85-92. PMID 29291494 DOI: 10.1016/J.Copbio.2017.12.018  0.487
2017 Williams A, He W, Cress BF, Liu X, Alexandria J, Yoshizawa H, Nishimura K, Toida T, Koffas M, Linhardt RJ. Cloning and expression of recombinant chondroitinase AC II and its comparison to the Arthrobacter aurescens enzyme. Biotechnology Journal. PMID 28799715 DOI: 10.1002/Biot.201700239  0.367
2017 Wang H, He W, Jiang P, Yu Y, Lin L, Sun X, Koffas M, Zhang F, Linhardt RJ. Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans. Glycoconjugate Journal. PMID 28752383 DOI: 10.1007/S10719-017-9786-3  0.334
2017 Cress BF, Leitz QD, Kim DC, Amore TD, Suzuki JY, Linhardt RJ, Koffas MA. CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production. Microbial Cell Factories. 16: 10. PMID 28095853 DOI: 10.1186/S12934-016-0623-3  0.357
2017 Englaender JA, Jones JA, Cress BF, Kuhlman TE, Linhardt RJ, Koffas MA. Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli. Acs Synthetic Biology. PMID 28055177 DOI: 10.1021/Acssynbio.6B00350  0.333
2016 He L, Xiu Y, Jones JA, Baidoo EE, Keasling JD, Tang YJ, Koffas MA. Deciphering flux adjustments of engineered E. coli cells during fermentation with changing growth conditions. Metabolic Engineering. PMID 28017690 DOI: 10.1016/J.Ymben.2016.12.008  0.335
2016 Whitaker WB, Jones JA, Bennett K, Gonzalez J, Vernacchio VR, Collins SM, Palmer MA, Schmidt S, Antoniewicz MR, Koffas MA, Papoutsakis ET. Engineering the Biological Conversion of Methanol to Specialty Chemicals in Escherichia coli. Metabolic Engineering. PMID 27815193 DOI: 10.1016/J.Ymben.2016.10.015  0.708
2016 Wu G, Yan Q, Jones JA, Tang YJ, Fong SS, Koffas MA. Metabolic Burden: Cornerstones in Synthetic Biology and Metabolic Engineering Applications. Trends in Biotechnology. PMID 26996613 DOI: 10.1016/J.Tibtech.2016.02.010  0.327
2016 Pandey RP, Parajuli P, Koffas MA, Sohng JK. Microbial production of natural and non-natural flavonoids: Pathway engineering, directed evolution and systems/synthetic biology. Biotechnology Advances. PMID 26946281 DOI: 10.1016/j.biotechadv.2016.02.012  0.412
2016 Jones JA, Vernacchio VR, Sinkoe AL, Collins SM, Ibrahim MH, Lachance DM, Hahn J, Koffas MA. "Experimental and computational optimization of an Escherichia coli co-culture for the efficient production of flavonoids". Metabolic Engineering. PMID 26860871 DOI: 10.1016/J.Ymben.2016.01.006  0.352
2015 Wang J, Guleria S, Koffas MA, Yan Y. Microbial production of value-added nutraceuticals. Current Opinion in Biotechnology. 37: 97-104. PMID 26716360 DOI: 10.1016/J.Copbio.2015.11.003  0.624
2015 Jones JA, Collins SM, Lachance DM, Vernacchio VR, Koffas MA. "Optimization of naringenin and p-coumaric acid hydroxylation using the native E. coli hydroxylase complex, HpaBC". Biotechnology Progress. PMID 26488898 DOI: 10.1002/btpr.2185  0.412
2015 Cress BF, Trantas EA, Ververidis F, Linhardt RJ, Koffas MA. Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways. Current Opinion in Biotechnology. 36: 205-214. PMID 26453934 DOI: 10.1016/J.Copbio.2015.09.007  0.42
2015 Suflita M, Fu L, He W, Koffas M, Linhardt RJ. Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering. Applied Microbiology and Biotechnology. 99: 7465-79. PMID 26219501 DOI: 10.1007/S00253-015-6821-9  0.494
2015 Lim CG, Wong L, Bhan N, Dvora H, Xu P, Venkiteswaran S, Koffas MA. Development of a Recombinant Escherichia coli Strain for Overproduction of the Plant Pigment Anthocyanin. Applied and Environmental Microbiology. 81: 6276-84. PMID 26150456 DOI: 10.1128/AEM.01448-15  0.403
2015 Jones JA, Vernacchio VR, Lachance DM, Lebovich M, Fu L, Shirke AN, Schultz VL, Cress B, Linhardt RJ, Koffas MA. ePathOptimize: A Combinatorial Approach for Transcriptional Balancing of Metabolic Pathways. Scientific Reports. 5: 11301. PMID 26062452 DOI: 10.1038/Srep11301  0.373
2015 Bhan N, Cress BF, Linhardt RJ, Koffas M. Expanding the chemical space of polyketides through structure-guided mutagenesis of Vitis vinifera stilbene synthase. Biochimie. 115: 136-43. PMID 26048582 DOI: 10.1016/J.Biochi.2015.05.019  0.357
2015 Cress BF, Toparlak ÖD, Guleria S, Lebovich M, Stieglitz JT, Englaender JA, Jones JA, Linhardt RJ, Koffas MA. CRISPathBrick: Modular Combinatorial Assembly of Type II-A CRISPR Arrays for dCas9-Mediated Multiplex Transcriptional Repression in E. coli. Acs Synthetic Biology. 4: 987-1000. PMID 25822415 DOI: 10.1021/Acssynbio.5B00012  0.309
2015 Trantas EA, Koffas MA, Xu P, Ververidis F. When plants produce not enough or at all: metabolic engineering of flavonoids in microbial hosts. Frontiers in Plant Science. 6: 7. PMID 25688249 DOI: 10.3389/fpls.2015.00007  0.474
2015 Zhao S, Jones JA, Lachance DM, Bhan N, Khalidi O, Venkataraman S, Wang Z, Koffas MA. Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering. Metabolic Engineering. 28: 43-53. PMID 25527438 DOI: 10.1016/J.Ymben.2014.12.002  0.376
2015 He W, Fu L, Li G, Andrew Jones J, Linhardt RJ, Koffas M. Production of chondroitin in metabolically engineered E. coli. Metabolic Engineering. 27: 92-100. PMID 25461828 DOI: 10.1016/J.Ymben.2014.11.003  0.416
2015 Jones JA, Toparlak ÖD, Koffas MA. Metabolic pathway balancing and its role in the production of biofuels and chemicals. Current Opinion in Biotechnology. 33: 52-59. PMID 25445548 DOI: 10.1016/j.copbio.2014.11.013  0.324
2014 Xu P, Li L, Zhang F, Stephanopoulos G, Koffas M. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proceedings of the National Academy of Sciences of the United States of America. 111: 11299-304. PMID 25049420 DOI: 10.1073/Pnas.1406401111  0.64
2014 Mora-Pale M, Sanchez-Rodriguez SP, Linhardt RJ, Dordick JS, Koffas MA. Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential. Current Opinion in Biotechnology. 25: 86-94. PMID 24484885 DOI: 10.1016/J.Copbio.2013.09.009  0.379
2013 Wang W, Englaender JA, Xu P, Mehta KK, Suwan J, Dordick JS, Zhang F, Yuan Q, Linhardt RJ, Koffas M. Expression of low endotoxin 3-O-sulfotransferase in Bacillus subtilis and Bacillus megaterium. Applied Biochemistry and Biotechnology. 171: 954-62. PMID 23912211 DOI: 10.1007/S12010-013-0415-8  0.36
2013 Mora-Pale M, Sanchez-Rodriguez SP, Linhardt RJ, Dordick JS, Koffas MA. Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues. Plant Science : An International Journal of Experimental Plant Biology. 210: 10-24. PMID 23849109 DOI: 10.1016/J.Plantsci.2013.05.005  0.473
2013 Bhan N, Xu P, Koffas MA. Pathway and protein engineering approaches to produce novel and commodity small molecules. Current Opinion in Biotechnology. 24: 1137-43. PMID 23498845 DOI: 10.1016/j.copbio.2013.02.019  0.377
2013 Xu P, Gu Q, Wang W, Wong L, Bower AG, Collins CH, Koffas MA. Modular optimization of multi-gene pathways for fatty acids production in E. coli. Nature Communications. 4: 1409. PMID 23361000 DOI: 10.1038/Ncomms2425  0.622
2013 Xu P, Bhan N, Koffas MA. Engineering plant metabolism into microbes: from systems biology to synthetic biology. Current Opinion in Biotechnology. 24: 291-9. PMID 22985679 DOI: 10.1016/j.copbio.2012.08.010  0.421
2012 Xu P, Vansiri A, Bhan N, Koffas MA. ePathBrick: a synthetic biology platform for engineering metabolic pathways in E. coli. Acs Synthetic Biology. 1: 256-66. PMID 23651248 DOI: 10.1021/sb300016b  0.351
2012 Malla S, Koffas MA, Kazlauskas RJ, Kim BG. Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli. Applied and Environmental Microbiology. 78: 684-94. PMID 22101053 DOI: 10.1128/Aem.06274-11  0.413
2011 Fowler ZL, Shah K, Panepinto JC, Jacobs A, Koffas MA. Development of non-natural flavanones as antimicrobial agents. Plos One. 6: e25681. PMID 22039419 DOI: 10.1371/Journal.Pone.0025681  0.761
2011 Xu P, Ranganathan S, Fowler ZL, Maranas CD, Koffas MA. Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. Metabolic Engineering. 13: 578-87. PMID 21763447 DOI: 10.1016/J.Ymben.2011.06.008  0.796
2011 Lim CG, Fowler ZL, Hueller T, Schaffer S, Koffas MA. High-yield resveratrol production in engineered Escherichia coli. Applied and Environmental Microbiology. 77: 3451-60. PMID 21441338 DOI: 10.1128/Aem.02186-10  0.804
2011 Fowler ZL, Baron CM, Panepinto JC, Koffas MA. Melanization of flavonoids by fungal and bacterial laccases. Yeast (Chichester, England). 28: 181-8. PMID 21360730 DOI: 10.1002/Yea.1829  0.771
2011 Santos CN, Koffas M, Stephanopoulos G. Optimization of a heterologous pathway for the production of flavonoids from glucose. Metabolic Engineering. 13: 392-400. PMID 21320631 DOI: 10.1016/J.Ymben.2011.02.002  0.668
2010 Chemler JA, Lim CG, Daiss JL, Koffas MA. A versatile microbial system for biosynthesis of novel polyphenols with altered estrogen receptor binding activity. Chemistry & Biology. 17: 392-401. PMID 20416510 DOI: 10.1016/J.Chembiol.2010.03.010  0.711
2010 Bedekar A, Shah K, Koffas M. Natural products for type II diabetes treatment. Advances in Applied Microbiology. 71: 21-73. PMID 20378050 DOI: 10.1016/S0065-2164(10)71002-9  0.393
2010 Chemler JA, Fowler ZL, McHugh KP, Koffas MA. Improving NADPH availability for natural product biosynthesis in Escherichia coli by metabolic engineering. Metabolic Engineering. 12: 96-104. PMID 19628048 DOI: 10.1016/J.Ymben.2009.07.003  0.8
2010 Xu P, Koffas MA. Metabolic engineering ofEscherichia colifor biofuel production Biofuels. 1: 493-504. DOI: 10.4155/bfs.10.13  0.351
2009 Fowler ZL, Gikandi WW, Koffas MA. Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. Applied and Environmental Microbiology. 75: 5831-9. PMID 19633125 DOI: 10.1128/Aem.00270-09  0.799
2009 Fowler ZL, Koffas MA. Biosynthesis and biotechnological production of flavanones: current state and perspectives. Applied Microbiology and Biotechnology. 83: 799-808. PMID 19475406 DOI: 10.1007/S00253-009-2039-Z  0.79
2009 Chemier JA, Fowler ZL, Koffas MA, Leonard E. Trends in microbial synthesis of natural products and biofuels. Advances in Enzymology and Related Areas of Molecular Biology. 76: 151-217. PMID 18990830 DOI: 10.1002/9780470392881.Ch4  0.8
2008 Chemler JA, Koffas MA. Metabolic engineering for plant natural product biosynthesis in microbes. Current Opinion in Biotechnology. 19: 597-605. PMID 18992815 DOI: 10.1016/J.Copbio.2008.10.011  0.78
2008 Leonard E, Yan Y, Fowler ZL, Li Z, Lim CG, Lim KH, Koffas MA. Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids. Molecular Pharmaceutics. 5: 257-65. PMID 18333619 DOI: 10.1021/Mp7001472  0.823
2008 Yan Y, Li Z, Koffas MA. High-yield anthocyanin biosynthesis in engineered Escherichia coli. Biotechnology and Bioengineering. 100: 126-40. PMID 18023053 DOI: 10.1002/Bit.21721  0.598
2008 Leonard E, Yan Y, Chemler J, Matern U, Martens S, Koffas MA. Characterization of dihydroflavonol 4-reductases for recombinant plant pigment biosynthesis applications Biocatalysis and Biotransformation. 26: 243-251. DOI: 10.1080/10242420701685635  0.801
2008 Koffas M. Engineering flavonoid biosynthesis in microorganisms Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 150: S184. DOI: 10.1016/J.Cbpa.2008.04.497  0.364
2007 Chemler JA, Lock LT, Koffas MA, Tzanakakis ES. Standardized biosynthesis of flavan-3-ols with effects on pancreatic beta-cell insulin secretion. Applied Microbiology and Biotechnology. 77: 797-807. PMID 17938905 DOI: 10.1007/S00253-007-1227-Y  0.768
2007 Leonard E, Koffas MA. Engineering of artificial plant cytochrome P450 enzymes for synthesis of isoflavones by Escherichia coli. Applied and Environmental Microbiology. 73: 7246-51. PMID 17905887 DOI: 10.1128/AEM.01411-07  0.73
2007 Yan Y, Huang L, Koffas MA. Biosynthesis of 5-deoxyflavanones in microorganisms. Biotechnology Journal. 2: 1250-62. PMID 17806100 DOI: 10.1002/Biot.200700119  0.654
2007 Leonard E, Lim KH, Saw PN, Koffas MA. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. Applied and Environmental Microbiology. 73: 3877-86. PMID 17468269 DOI: 10.1128/AEM.00200-07  0.741
2007 Chemler JA, Yan Y, Leonard E, Koffas MA. Combinatorial mutasynthesis of flavonoid analogues from acrylic acids in microorganisms. Organic Letters. 9: 1855-8. PMID 17447772 DOI: 10.1021/Ol0703736  0.778
2006 Chemler JA, Yan Y, Koffas MA. Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. Microbial Cell Factories. 5: 20. PMID 16719921 DOI: 10.1186/1475-2859-5-20  0.794
2006 Leonard E, Yan Y, Koffas MA. Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli. Metabolic Engineering. 8: 172-81. PMID 16384722 DOI: 10.1016/J.Ymben.2005.11.001  0.777
2006 Leonard E, Chemler J, Lim KH, Koffas MA. Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli. Applied Microbiology and Biotechnology. 70: 85-91. PMID 16025328 DOI: 10.1007/S00253-005-0059-X  0.816
2005 Leonard E, Yan Y, Lim KH, Koffas MA. Investigation of two distinct flavone synthases for plant-specific flavone biosynthesis in Saccharomyces cerevisiae. Applied and Environmental Microbiology. 71: 8241-8. PMID 16332809 DOI: 10.1128/Aem.71.12.8241-8248.2005  0.752
2005 Yan Y, Kohli A, Koffas MA. Biosynthesis of natural flavanones in Saccharomyces cerevisiae. Applied and Environmental Microbiology. 71: 5610-3. PMID 16151160 DOI: 10.1128/Aem.71.9.5610-5613.2005  0.553
2005 Yan Y, Chemler J, Huang L, Martens S, Koffas MA. Metabolic engineering of anthocyanin biosynthesis in Escherichia coli. Applied and Environmental Microbiology. 71: 3617-23. PMID 16000769 DOI: 10.1128/Aem.71.7.3617-3623.2005  0.816
2005 Koffas M, Stephanopoulos G. Strain improvement by metabolic engineering: lysine production as a case study for systems biology. Current Opinion in Biotechnology. 16: 361-6. PMID 15961038 DOI: 10.1016/J.Copbio.2005.04.010  0.602
2005 Koffas M, Cardayre Sd. Evolutionary metabolic engineering Metabolic Engineering. 7: 1-3. DOI: 10.1016/J.Ymben.2005.01.001  0.375
2003 Koffas MA, Jung GY, Stephanopoulos G. Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression. Metabolic Engineering. 5: 32-41. PMID 12749842 DOI: 10.1016/S1096-7176(03)00002-8  0.718
2002 Koffas MA, Jung GY, Aon JC, Stephanopoulos G. Effect of pyruvate carboxylase overexpression on the physiology of Corynebacterium glutamicum. Applied and Environmental Microbiology. 68: 5422-8. PMID 12406733 DOI: 10.1128/Aem.68.11.5422-5428.2002  0.677
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