Jesus Florez - Publications

Affiliations: 
University of Cantabria, Santander, Cantabria, Spain 

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rueda N, Flórez J, Dierssen M, Martínez-Cué C. Translational validity and implications of pharmacotherapies in preclinical models of Down syndrome. Progress in Brain Research. 251: 245-268. PMID 32057309 DOI: 10.1016/Bs.Pbr.2019.10.001  0.64
2015 De la Campa R, Flórez J. Water freezing as a regiocontrol element in the multicomponent assembly of cyclic enones. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1854-9. PMID 25418199 DOI: 10.1002/chem.201404670  0.64
2014 García-Cerro S, Martínez P, Vidal V, Corrales A, Flórez J, Vidal R, Rueda N, Arbonés ML, Martínez-Cué C. Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome. Plos One. 9: e106572. PMID 25188425 DOI: 10.1371/Journal.Pone.0106572  0.64
2014 Corrales A, Vidal R, García S, Vidal V, Martínez P, García E, Flórez J, Sanchez-Barceló EJ, Martínez-Cué C, Rueda N. Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome. Journal of Pineal Research. 56: 51-61. PMID 24147912 DOI: 10.1111/Jpi.12097  0.64
2014 García-Cerro S, Martinez P, Vidal V, Corrales A, Flórez J, Vidal R, Rueda N, Arbonés ML, Martínez-Cué C. Normalization of the Dyrk1A gene dosage increased cell proliferation and differentiation in the DG but did not rescue the density of mature granule neurons. Plos One. DOI: 10.1371/Journal.Pone.0106572.G006  0.48
2013 Martínez-Cué C, Martínez P, Rueda N, Vidal R, García S, Vidal V, Corrales A, Montero JA, Pazos Á, Flórez J, Gasser R, Thomas AW, Honer M, Knoflach F, Trejo JL, et al. Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3953-66. PMID 23447605 DOI: 10.1523/Jneurosci.1203-12.2013  0.76
2013 Corrales A, Martínez P, García S, Vidal V, García E, Flórez J, Sanchez-Barceló EJ, Martínez-Cué C, Rueda N. Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome. Journal of Pineal Research. 54: 346-58. PMID 23350971 DOI: 10.1111/Jpi.12037  0.64
2013 Rueda N, Flórez J, Martínez-Cué C. Apoptosis in Down's syndrome: lessons from studies of human and mouse models. Apoptosis : An International Journal On Programmed Cell Death. 18: 121-34. PMID 23224708 DOI: 10.1007/S10495-012-0785-3  0.64
2012 Vidal V, García S, Martínez P, Corrales A, Flórez J, Rueda N, Sharma A, Martínez-Cué C. Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome. Neuroscience. 220: 158-68. PMID 22728103 DOI: 10.1016/J.Neuroscience.2012.06.031  0.76
2012 Rueda N, Flórez J, Martínez-Cué C. Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities. Neural Plasticity. 2012: 584071. PMID 22685678 DOI: 10.1155/2012/584071  0.64
2011 Baamonde C, Martínez-Cué C, Flórez J, Dierssen M. G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model. Developmental Neuroscience. 33: 442-50. PMID 21865666 DOI: 10.1159/000329425  0.64
2011 Rueda N, Flórez J, Martínez-Cué C. The Ts65Dn mouse model of Down syndrome shows reduced expression of the Bcl-X(L) antiapoptotic protein in the hippocampus not accompanied by changes in molecular or cellular markers of cell death. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 29: 711-6. PMID 21684326 DOI: 10.1016/J.Ijdevneu.2011.06.001  0.64
2011 Dierssen M, Arqué G, McDonald J, Andreu N, Martínez-Cué C, Flórez J, Fillat C. Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1. Plos One. 6: e17010. PMID 21364922 DOI: 10.1371/Journal.Pone.0017010  0.64
2011 Corbin JG, Paluszkiewicz SM, Martin BS, Huntsman MM, Tranfaglia MR, Liu C, Belichenko PV, Zhang L, Fu D, Kleschevnikov AM, Baldini A, Antonarakis SE, Mobley WC, Yu YE, Chakrabarti L, et al. Author and Subject Index Developmental Neuroscience. 33: 468-468. DOI: 10.1159/000334885  0.64
2010 Llorens-Martín MV, Rueda N, Tejeda GS, Flórez J, Trejo JL, Martínez-Cué C. Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome. Neuroscience. 171: 1228-40. PMID 20875841 DOI: 10.1016/J.Neuroscience.2010.09.043  0.64
2010 Rueda N, Llorens-Martín M, Flórez J, Valdizán E, Banerjee P, Trejo JL, Martínez-Cué C. Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome. Journal of Alzheimer's Disease : Jad. 21: 277-90. PMID 20421694 DOI: 10.3233/Jad-2010-100240  0.64
2008 Barluenga J, Trabanco AA, Pérez-Sánchez I, De la Campa R, Flórez J, García-Granda S, Aguirre A. Mononuclear biscarbene complexes by direct nucleophile addition to a CO ligand of Fischer arylcarbene complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 5401-4. PMID 18446917 DOI: 10.1002/Chem.200800452  0.64
2008 Rueda N, Flórez J, Martínez-Cué C. Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome. Neuroscience Letters. 433: 22-7. PMID 18226451 DOI: 10.1016/J.Neulet.2007.12.039  0.64
2008 Rueda N, Flórez J, Martínez-Cué C. Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome. Behavioural Brain Research. 188: 355-67. PMID 18178265 DOI: 10.1016/J.Bbr.2007.11.020  0.64
2007 Llorens-Martín MV, Rueda N, Martínez-Cué C, Torres-Alemán I, Flórez J, Trejo JL. Both increases in immature dentate neuron number and decreases of immobility time in the forced swim test occurred in parallel after environmental enrichment of mice. Neuroscience. 147: 631-8. PMID 17570601 DOI: 10.1016/J.Neuroscience.2007.04.054  0.64
2007 Barluenga J, Fanlo H, López S, Flórez J. [4+1]/[2+1] Cycloaddition reactions of Fischer carbene complexes with alpha,beta-unsaturated ketones and aldehydes. Angewandte Chemie (International Ed. in English). 46: 4136-40. PMID 17440911 DOI: 10.1002/Anie.200605167  0.64
2006 Dierssen M, Gratacòs M, Sahún I, Martín M, Gallego X, Amador-Arjona A, Martínez de Lagrán M, Murtra P, Martí E, Pujana MA, Ferrer I, Dalfó E, Martínez-Cué C, Flórez J, Torres-Peraza JF, et al. Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction. Neurobiology of Disease. 24: 403-18. PMID 16963267 DOI: 10.1016/J.Nbd.2006.07.015  0.76
2006 Martínez-Cué C, Rueda N, García E, Flórez J. Anxiety and panic responses to a predator in male and female Ts65Dn mice, a model for Down syndrome. Genes, Brain, and Behavior. 5: 413-22. PMID 16879635 DOI: 10.1111/J.1601-183X.2005.00175.X  0.64
2006 Lumbreras M, Baamonde C, Martínez-Cué C, Lubec G, Cairns N, Sallés J, Dierssen M, Flórez J. Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease. Amino Acids. 31: 449-56. PMID 16583316 DOI: 10.1007/S00726-005-0272-Z  0.64
2005 Martínez-Cué C, Rueda N, García E, Davisson MT, Schmidt C, Flórez J. Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome. Behavioural Brain Research. 163: 174-85. PMID 15941601 DOI: 10.1016/J.Bbr.2005.04.016  0.64
2005 Rueda N, Mostany R, Pazos A, Flórez J, Martínez-Cué C. Cell proliferation is reduced in the dentate gyrus of aged but not young Ts65Dn mice, a model of Down syndrome. Neuroscience Letters. 380: 197-201. PMID 15854777 DOI: 10.1016/J.Neulet.2005.01.039  0.76
2003 Barluenga J, Pérez-Sánchez I, Rubio E, Flórez J. Three/four/five-component diastereoselective cyclization of Fischer carbene complexes, lithium enolates, and allylmagnesium bromide. Angewandte Chemie (International Ed. in English). 42: 5860-3. PMID 14673919 DOI: 10.1002/Anie.200352489  0.64
2003 Barluenga J, Nandy SK, Laxmi YR, Suárez JR, Merino I, Flórez J, García-Granda S, Montejo-Bernardo J. Asymmetric dearomatization of the furan ring promoted by conjugate organolithium addition to (menthyloxy)(3-furyl)carbene complexes of chromium. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 5725-36. PMID 14673842 DOI: 10.1002/Chem.200305241  0.64
2003 Dierssen M, Benavides-Piccione R, Martínez-Cué C, Estivill X, Flórez J, Elston GN, DeFelipe J. Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment. Cerebral Cortex (New York, N.Y. : 1991). 13: 758-64. PMID 12816891 DOI: 10.1093/Cercor/13.7.758  0.76
2003 Barluenga J, López S, Flórez J. [3+2] and [4+1] cycloaddition reactions of Fischer alkoxy(alkenyl)carbene complexes with electronically neutral 1,3-dienes. Angewandte Chemie (International Ed. in English). 42: 231-3. PMID 12532359 DOI: 10.1002/Anie.200390087  0.64
2002 Martínez-Cué C, Baamonde C, Lumbreras M, Paz J, Davisson MT, Schmidt C, Dierssen M, Flórez J. Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome. Behavioural Brain Research. 134: 185-200. PMID 12191805 DOI: 10.1016/S0166-4328(02)00026-8  0.64
2002 Baamonde C, Lumbreras MA, MartInez-Cué C, Vallina IF, Flórez J, Dierssen M. Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats. Stress (Amsterdam, Netherlands). 5: 137-47. PMID 12186692 DOI: 10.1080/10253890290027903  0.64
2002 Barluenga J, Diéguez A, Rodríguez F, Flórez J, Fañanás FJ. One-pot enantioselective formation of eight-membered rings from alkenyl Fischer carbene complexes and ketone enolates. Journal of the American Chemical Society. 124: 9056-7. PMID 12149002 DOI: 10.1021/Ja0264551  0.64
2002 Díaz A, Pazos A, Flórez J, Ayesta FJ, Santana V, Hurlé MA. Regulation of mu-opioid receptors, G-protein-coupled receptor kinases and beta-arrestin 2 in the rat brain after chronic opioid receptor antagonism. Neuroscience. 112: 345-53. PMID 12044452 DOI: 10.1016/S0306-4522(02)00073-8  0.76
2002 Garcia-Calatayud S, Ruiz JI, García-Fuentes M, Dierssen M, Flórez J, Crespo PS. Long-chain polyunsaturated fatty acids in rat maternal milk, offspring brain and peripheral tissues in essential fatty acid deficiency. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 40: 278-84. PMID 12005218 DOI: 10.1515/Cclm.2002.044  0.64
2002 Merino I, Laxmi Y R S, Flórez J, Barluenga J, Ezquerra J, Pedregal C. Stereoselective formal [3 + 2] cycloaddition of N-alkylidene glycine ester anions to chiral Fischer alkenylcarbene complexes. Asymmetric synthesis of 3,4,5-trisubstituted prolines. The Journal of Organic Chemistry. 67: 648-55. PMID 11856002 DOI: 10.1021/Jo010485P  0.64
2001 Barluenga J, López S, Trabanco AA, Flórez J. 2- and 3-haloalkoxy fischer carbene complexes of chromium as synthons for either hydroxycyclopropanation or oxaspirocyclopropanation of alkenes. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4723-9. PMID 11757665 DOI: 10.1002/1521-3765(20011105)7:21<4723::Aid-Chem4723>3.0.Co;2-V  0.64
2001 Ruiz de Azúa I, Lumbreras MA, Zalduegui A, Baamonde C, Dierssen M, Flórez J, Sallés J. Reduced phospholipase C-beta activity and isoform expression in the cerebellum of TS65Dn mouse: a model of Down syndrome. Journal of Neuroscience Research. 66: 540-50. PMID 11746373 DOI: 10.1002/Jnr.10019  0.64
2001 Dierssen M, Fillat C, Crnic L, Arbonés M, Flórez J, Estivill X. Murine models for Down syndrome. Physiology & Behavior. 73: 859-71. PMID 11566219 DOI: 10.1016/S0031-9384(01)00523-6  0.64
2001 Altafaj X, Dierssen M, Baamonde C, Martí E, Visa J, Guimerà J, Oset M, González JR, Flórez J, Fillat C, Estivill X. Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. Human Molecular Genetics. 10: 1915-23. PMID 11555628 DOI: 10.1093/Hmg/10.18.1915  0.64
2001 Casas C, Martínez S, Pritchard MA, Fuentes JJ, Nadal M, Guimerà J, Arbonés M, Flórez J, Soriano E, Estivill X, Alcántara S. Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis. Mechanisms of Development. 101: 289-92. PMID 11231093 DOI: 10.1016/S0925-4773(00)00583-9  0.64
2000 Chico A, Flórez J. What is your diagnosis? Spinal nephroblastoma. The Journal of Small Animal Practice. 41: 439, 472-3. PMID 11072910  0.64
2000 Díaz A, Pazos A, Flórez J, Hurlé MA. Autoradiographic mapping of mu-opioid receptors during opiate tolerance and supersensitivity in the rat central nervous system. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 101-9. PMID 10961371 DOI: 10.1007/S002100000258  0.76
2000 Díaz A, Flórez J, Pazos A, Hurlé MA. Opioid tolerance and supersensitivity induce regional changes in the autoradiographic density of dihydropyridine-sensitive calcium channels in the rat central nervous system. Pain. 86: 227-35. PMID 10812252 DOI: 10.1016/S0304-3959(00)00249-9  0.76
2000 Kurt MA, Davies DC, Kidd M, Dierssen M, Flórez J. Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice. Brain Research. 858: 191-7. PMID 10700614 DOI: 10.1016/S0006-8993(00)01984-3  0.64
2000 Santillan R, Hurle MA, Armijo JA, De los Mozos R, Florez J. Nimodipine-enhanced opiate analgesia in cancer patients requiring morphine dose escalation: A double-blind, place-controlled study | Analgesia opiacea potenciada por nimodipino en enfermos de cancer que necesitan escalada de la dosis de morfina: Estudio doble ciego controlado con placebo Revista De La Sociedad Espanola Del Dolor. 7: 431-443.  0.76
1999 Ezquerra J, Pedregal C, Merino I, Flórez J, Barluenga J, García-Granda S, Llorca MA. Stereoselective Michael Addition of Glycine Anions to Chiral Fischer Alkenylcarbene Complexes. Asymmetric Synthesis of beta-Substituted Glutamic Acids. The Journal of Organic Chemistry. 64: 6554-6565. PMID 11674657 DOI: 10.1021/Jo9819739  0.64
1999 Baamonde C, Lumbreras MA, Martínez-Cué C, Vallina IF, García-Calatayud S, Flórez J, Dierssen M. Short-term effects of postnatal manipulation on central beta-adrenoceptor transmission. Stress (Amsterdam, Netherlands). 3: 147-62. PMID 10938576 DOI: 10.3109/10253899909001119  0.64
1999 Martínez-Cué C, Baamonde C, Lumbreras MA, Vallina IF, Dierssen M, Flórez J. A murine model for Down syndrome shows reduced responsiveness to pain. Neuroreport. 10: 1119-22. PMID 10321494  0.64
1998 Insausti AM, Megías M, Crespo D, Cruz-Orive LM, Dierssen M, Vallina IF, Insausti R, Flórez J, Vallina TF. Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome. Neuroscience Letters. 253: 175-8. PMID 9792239 DOI: 10.1016/S0304-3940(98)00641-7  0.64
1998 Santillán R, Hurlé MA, Armijo JA, de los Mozos R, Flórez J. Nimodipine-enhanced opiate analgesia in cancer patients requiring morphine dose escalation: a double-blind, placebo-controlled study. Pain. 76: 17-26. PMID 9696455 DOI: 10.1016/S0304-3959(98)00019-0  0.64
1998 Escorihuela RM, Vallina IF, Martínez-Cué C, Baamonde C, Dierssen M, Tobeña A, Flórez J, Fernández-Teruel A. Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome. Neuroscience Letters. 247: 171-4. PMID 9655620 DOI: 10.1016/S0304-3940(98)00317-6  0.64
1997 Megías M, Verduga R, Dierssen M, Flórez J, Insausti R, Crespo D. Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice. Neuroreport. 8: 3475-8. PMID 9427310 DOI: 10.1097/00001756-199711100-00012  0.64
1997 Flórez J, García-Pardo G, Auguet T, Sirvent JJ, Bel M, Richart C. Pelvic mass in 46-year old man. Postgraduate Medical Journal. 73: 371-3. PMID 9246348  0.64
1997 Dierssen M, Vallina IF, Baamonde C, García-Calatayud S, Lumbreras MA, Flórez J. Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome. Brain Research. 749: 238-44. PMID 9138724 DOI: 10.1016/S0006-8993(96)01173-0  0.64
1996 Barluenga J, Canteli RM, Flórez J. Thermal Cyclodimerization of Aliphatic Secondary C,N-Dilithioallylamine Derivatives. The Journal of Organic Chemistry. 61: 3753-3757. PMID 11667225 DOI: 10.1021/Jo960048O  0.64
1996 Barluenga J, Canteli RM, Flórez J. Novel Cleavage of Propargylamines by Reaction with Organolithium Compounds. The Journal of Organic Chemistry. 61: 3646-3649. PMID 11667210 DOI: 10.1021/Jo960025+  0.64
1996 Dierssen M, Vallina IF, Baamonde C, Lumbreras MA, Martínez-Cué C, Calatayud SG, Flórez J. Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model. Brain Research. Developmental Brain Research. 95: 122-4. PMID 8873983 DOI: 10.1016/0165-3806(96)00071-5  0.64
1996 García-Pardo G, Martinez-Vea A, Auguet T, Flórez J, Oliver JA, Richart C. Intestinal obstruction complicating calcium polystyrene sulphonate therapy. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 11: 751. PMID 8671882  0.64
1995 Escorihuela RM, Fernández-Teruel A, Vallina IF, Baamonde C, Lumbreras MA, Dierssen M, Tobeña A, Flórez J. A behavioral assessment of Ts65Dn mice: a putative Down syndrome model. Neuroscience Letters. 199: 143-6. PMID 8584244 DOI: 10.1016/0304-3940(95)12052-6  0.64
1995 Diaz A, Ruiz F, Flórez J, Hurlé MA, Pazos A. Mu-opioid receptor regulation during opioid tolerance and supersensitivity in rat central nervous system. The Journal of Pharmacology and Experimental Therapeutics. 274: 1545-51. PMID 7562532  0.76
1995 Díaz A, Ruíz F, Flórez J, Pazos A, Hurlé MA. Regulation of dihydropyridine-sensitive Ca++ channels during opioid tolerance and supersensitivity in rats. The Journal of Pharmacology and Experimental Therapeutics. 274: 1538-44. PMID 7562531  0.76
1994 Santillán R, Maestre JM, Hurlé MA, Flórez J. Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report. Pain. 58: 129-32. PMID 7970835 DOI: 10.1016/0304-3959(94)90192-9  0.64
1994 Calvo-Alén J, De Cos MA, Rodríguez-Valverde V, Escallada R, Florez J, Arias M. Subclinical renal toxicity in rheumatic patients receiving longterm treatment with nonsteroidal antiinflammatory drugs. The Journal of Rheumatology. 21: 1742-7. PMID 7799360  0.76
1994 Hurlé M, Díaz A, Ruiz F, Flórez J, Pazos A. Functional and biochemical interactions between the calcium antagonist nimodipine and sufentanil Regulatory Peptides. 53: S17-S18. DOI: 10.1016/0167-0115(94)90219-4  0.76
1993 Flórez J, Vidal F, García-Queralt R, Richart C. [Visceral leishmaniasis in HIV-infected patients. A diagnostic criterion of AIDS?]. Revista Clã­Nica Espaã±Ola. 192: 249-50. PMID 8484047  0.64
1993 Ruiz F, Dierssen M, Flórez J, Hurlé MA. Potentiation of acute opioid-induced respiratory depression and reversal of tolerance by the calcium antagonist nimodipine in awake rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 633-7. PMID 8133906 DOI: 10.1007/Bf00167240  0.64
1993 Ruiz F, Dierssen M, Flórez J, Hurlé MA. The Ca2+ channel agonist Bay K 8644 induces central respiratory depression in cats, an effect blocked by naloxone. European Journal of Pharmacology. 240: 155-61. PMID 7694855 DOI: 10.1016/0014-2999(93)90893-M  0.64
1992 Del Arco C, Riancho JA, Luzuriaga C, González-Macías J, Flórez J. Vitamin D status in children with Down's syndrome. Journal of Intellectual Disability Research : Jidr. 36: 251-7. PMID 1535819  0.76
1991 Pascual J, Fontán A, Zarranz JJ, Berciano J, Flórez J, Pazos A. High-affinity choline uptake carrier in Alzheimer's disease: implications for the cholinergic hypothesis of dementia. Brain Research. 552: 170-4. PMID 1913175 DOI: 10.1016/0006-8993(91)90676-M  0.64
1991 Dierssen M, Ruiz F, Flórez J, Hurlé MA. Ca2+ channel modulation by dihydropyridines modifies sufentanil-induced respiratory depression in cats. European Journal of Pharmacology. 198: 149-55. PMID 1713849 DOI: 10.1016/0014-2999(91)90614-V  0.64
1990 Flórez J, del Arco C, González A, Pascual J, Pazos A. Autoradiographic studies of neurotransmitter receptors in the brain of newborn infants with Down syndrome. American Journal of Medical Genetics. Supplement. 7: 301-5. PMID 2149965 DOI: 10.1002/Ajmg.1320370759  0.76
1990 Ayesta FJ, Flórez J. Tolerance to the respiratory actions of opiates: withdrawal tolerance and asymmetrical cross-tolerance. European Journal of Pharmacology. 175: 1-12. PMID 2138980 DOI: 10.1016/0014-2999(90)90145-V  0.64
1990 Dierssen M, Flórez J, Hurlé MA. Calcium channel modulation by dihydropyridines modifies sufentanil-induced antinociception in acute and tolerant conditions. Naunyn-Schmiedeberg's Archives of Pharmacology. 342: 559-65. PMID 1708855 DOI: 10.1007/Bf00169046  0.64
1990 Flórez J, Dierssen M, Hurlé MA. Opiate analgesia and calcium channels modulation by dihydropyridines under acute and tolerant conditions. Progress in Clinical and Biological Research. 328: 461-4. PMID 1689496  0.64
1990 Florez J, Dierssen M, Ruiz F, Hurle MA. Influence of Bay K 8644 on the respiratory centers and its interaction with opiate activity European Journal of Pharmacology. 183: 976. DOI: 10.1016/0014-2999(90)92819-5  0.76
1990 Pazos A, Pascual J, Fontan A, Zarranz JJ, Florez J. Selective reduction in the cerebral activity of high affinity choline uptake in Alzheimer's disease European Journal of Pharmacology. 183: 938. DOI: 10.1016/0014-2999(90)92776-F  0.76
1990 Hurle M, Dierssen M, Ruiz F, Florez J. Influence of calcium channel agonists on the opiate activity at the respiratory center of cats New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 344.  0.76
1989 Dierssen M, Flórez J, Hurlé MA. Lack of interaction between cholecystokinin and opioid systems in the central control of breathing. Revista Espaã±Ola De Fisiologã­A. 45: 185-90. PMID 2641818  0.76
1989 Ayesta FJ, Flórez J. Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance. The Journal of Pharmacology and Experimental Therapeutics. 250: 371-8. PMID 2568480  0.76
1989 Florez J. Education of experimental pharmacologists in Spain. II. Doctorate and teaching programs | FORMACION DE FARMACOLOGOS EXPERIMENTALES EN ESPANA. II. PROGRAMAS DE DOCTORADO Y DE MAGISTER Revista De Farmacologia Clinica Y Experimental. 6: 393-400.  0.76
1989 Florez J, Dierssen MM, Hurle MA. Calcium antagonists: Actions in the central nervous system Recent Advances in Pharmacology and Therapeutics: Proceedings of the Xii Latin-American Congress of Pharmacology and the Iii Inter-American Congress of Clinical Pharmacology and Therapeutics. Ics839. 77-82.  0.76
1988 Hurlé MA, Dierssen MM, Morin-Surun MP, Oceja C, Flórez J. Respiratory actions induced by cholecystokinin at the brainstem level. Peptides. 9: 809-15. PMID 3226957 DOI: 10.1016/0196-9781(88)90126-X  0.64
1988 Valiente R, Flórez J. [Practical value of determining the plasma levels of drugs]. Revista De Medicina De La Universidad De Navarra. 32: 21-8. PMID 3175436  0.64
1988 Valiente R, Flórez J. [The practical value of determination of plasma levels of drugs]. Revista De Medicina De La Universidad De Navarra. 32: 21-8. PMID 3154928  0.64
1986 Hurlé MA, Dierssen MM, Flórez J. Mechanism of the respiratory action of pentobarbital at the medullary and pontine levels. European Journal of Pharmacology. 125: 225-32. PMID 3017725 DOI: 10.1016/0014-2999(86)90031-2  0.64
1985 Hurlé MA, Mediavilla A, Flórez J. Differential respiratory patterns induced by opioids applied to the ventral medullary and dorsal pontine surfaces of cats. Neuropharmacology. 24: 597-606. PMID 3927184 DOI: 10.1016/0028-3908(85)90100-5  0.64
1984 Pazos A, López M, Flórez J. Different mechanisms are involved in the respiratory depression and analgesia induced by neurotensin in rats. European Journal of Pharmacology. 98: 119-23. PMID 6714297 DOI: 10.1016/0014-2999(84)90116-X  0.64
1984 Pazos A, Flórez J. A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists. European Journal of Pharmacology. 99: 15-21. PMID 6373310 DOI: 10.1016/0014-2999(84)90427-8  0.64
1983 Hurlé MA, Mediavilla A, Flórez J. Participation of pontine structures in the respiratory action of opioids. Life Sciences. 33: 571-4. PMID 6363854 DOI: 10.1016/0024-3205(83)90567-2  0.64
1983 Pazos A, Tristán C, Flórez J. A comparative study of the respiratory depressant and analgesic effects of bremazocine, a kappa-agonist. Life Sciences. 33: 579-81. PMID 6319913  0.64
1983 Pazos A, Flórez J. Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats. European Journal of Pharmacology. 87: 309-14. PMID 6301857 DOI: 10.1016/0014-2999(83)90343-6  0.72
1982 Riancho JA, del Arco C, Pazos A, Flórez J. Influence of dopamine-beta-hydroxylase inhibition on the cardiovascular and respiratory actions of dopamine in rats. Revista Espaã±Ola De Fisiologã­A. 38: 461-9. PMID 7170431  0.76
1982 Cotorruelo JG, Llamazares C, Flórez J. Minoxidil in severe and moderately severe hypertension, in association with methyldopa and chlortalidone. Angiology. 33: 710-9. PMID 7137653  0.76
1982 Hurlé MA, Mediavilla A, Flórez J. Morphine, pentobarbital and naloxone in the ventral medullary chemosensitive areas: differential respiratory and cardiovascular effects. The Journal of Pharmacology and Experimental Therapeutics. 220: 642-7. PMID 7062273  0.76
1982 Flórez J, Hurlé MA, Mediavilla A. Respiratory responses to opiates applied to the medullary ventral surface. Life Sciences. 31: 2189-92. PMID 6819420 DOI: 10.1016/0024-3205(82)90115-1  0.64
1982 Flórez J, Pazos A. Comparative effects of opioid peptides on respiration and analgesia in rats. Life Sciences. 31: 1275-7. PMID 6292613  0.76
1982 Pazos A, Mediavilla A, Flórez J. Cardiovascular effects of intracerebroventricular injection of dopamine after selective MAO inhibition in rats. Neuropharmacology. 21: 317-22. PMID 6283412 DOI: 10.1016/0028-3908(82)90094-6  0.64
1981 Mediavilla A, Pazos A, Flórez J. [Respiratory effects of intracerebroventricular dopamine in the rat]. Archivos De Farmacologã­a Y Toxicologã­A. 7: 73-6. PMID 7325719  0.76
1981 Padrón F, Sanz J, Flórez J. [Comparative study of antiemetic properties of clebopride and metoclopramide in vomiting produced by cis-platinum (author's transl)]. Medicina Clã­Nica. 77: 167-70. PMID 7031384  0.64
1981 Flórez J, Mediavilla A, Hurlé M. [Morphine and beta-endorphin in the S-region of the ventral surface of the medulla oblongata: respiratory and cardiovascular effects]. Archivos De Farmacologã­a Y Toxicologã­A. 7: 45-8. PMID 6275803  0.76
1980 Flórez J, Mediavilla A, Pazos A. Respiratory effects of beta-endorphin, D-Ala2-met-enkephalinamide, and Met-enkephalin injected into the lateral ventricle and the pontomedullary subarachnoid space. Brain Research. 199: 197-206. PMID 7407621 DOI: 10.1016/0006-8993(80)90240-1  0.64
1980 Herranz J, Luzuriaga C, Sarralle R, Flórez J. [Neurological symptoms precipitated by loperamide (author's transl)]. Anales Espaã±Oles De Pediatrã­A. 13: 1117-20. PMID 7224374  0.76
1979 Armijo JA, Mediavilla A, Flórez J. Inhibition of the activity of the respiratory and vasomotor centers by centrally administered 5-hydroxytryptamine in cats. Revista Espaã±Ola De Fisiologã­A. 35: 219-27. PMID 582627  0.76
1979 Mediavilla A, Feria M, Fernández JF, Cagigas P, Pazos A, Flórez J. The stimulatory action of d-amphetamine on the respiratory centre, and its mediation by a central alpha-adrenergic mechanism. Neuropharmacology. 18: 133-42. PMID 219384  0.64
1978 Padrón F, Flórez J. Blockade by intracerebroventricular phentolamine of the respiratory and cardiovascular effects of bromocriptine. Archivos De Farmacologã­a Y Toxicologã­A. 4: 211-20. PMID 31844  0.76
1977 Flórez J, Mediavilla A. Respiratory and cardiovascular effects of met-enkephalin applied to the ventral surface of the brain stem. Brain Research. 138: 585-900. PMID 597727  0.64
1975 Feria M, Armijo JA, Mediavilla A, Flórez J. The cardiovascular effects of naloxone in anesthetized rats. Archivos De Farmacologã­a Y Toxicologã­A. 1: 99-110. PMID 1230034  0.76
1974 Flórez J. The site of the respiratory stimulant action of imidazole in cats. Pharmacology. 11: 308-15. PMID 4855090  0.76
1974 Flórez J, Armijo JA. Effect of central inhibition of the 1-amino acid decarboxylase on the hypotensive action of 5-HT precursors in cats. European Journal of Pharmacology. 26: 108-10. PMID 4831977  0.64
1974 Armijo JA, Flórez J. The influence of increased brain 5-hydroxytryptamine upon the respiratory activity of cats. Neuropharmacology. 13: 977-86. PMID 4548170  0.64
1974 Florez J, Armijo JA. Effect of drug induced changes in serotonin on the respiratory center of cats Federation Proceedings. 33: I.  0.76
1974 Florez J. Neuropharmacologic principles of the treatment of drug addiction | FUNDAMENTOS NEUROFARMACOLOGICOS DEL TRATAMIENTO DE LA DROGADICCION An.Med.. 60: 286-309.  0.76
1973 Flórez J, Delgado G, Armijo JA. Brain amines and development of acute tolerance to and dependence on morphine in the respiratory center of decerebrate cats. Neuropharmacology. 12: 355-62. PMID 4267389 DOI: 10.1016/0028-3908(73)90095-6  0.76
1973 Florez J. Mechanism of the cardiotonic action of digitalis | MECANISMO DE LA ACCION CARDIOTONICA DE LA DIGITAL Acta Med.Tenerife. 34: 111-124.  0.76
1972 Flórez J, Armijo JA, Delgado G. Characterization of the acute tolerance and dependence to morphine-induced respiratory depression in decerebrate cats. Revista Espaã±Ola De Fisiologã­A. 28: 167-73. PMID 4679517  0.76
1972 Flórez J, Delgado G, Armijo JA. Adrenergic and serotonergic mechanisms in morphine-induced respiratory depression. Psychopharmacologia. 24: 258-74. PMID 4260589 DOI: 10.1007/BF00403646  0.76
1971 Flórez J. The action of diazepam, nitrazepam, and chlonazepam on the respiratory center of decerebrate cats. European Journal of Pharmacology. 14: 250-6. PMID 5156144  0.64
1971 Flórez J, Arconada JA. Comparison of the anti-arrhythmic action and beta-blocking potency of LB 46 and (--)-propranolol. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 190: 199-207. PMID 4396347  0.64
1969 Flórez J, Borison HL. Effects of central depressant drugs on respiratory regulation in the decerebrate cat. Respiration Physiology. 6: 318-29. PMID 5778478  0.64
1969 Flórez J, Pomar JL, Malpartida F. Beta-adrenergic blockade and antiarrhythmic activity of (-)- and (+)-propranolol. Revista Espaã±Ola De Fisiologã­A. 25: 287-92. PMID 4401670  0.64
1968 Flórez J, McCarthy LE, Borison HL. A comparative study in the cat of the respiratory effects of morphine injected intravenously and into the cerebrospinal fluid. The Journal of Pharmacology and Experimental Therapeutics. 163: 448-55. PMID 4878662  0.64
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