Harpreet Singh, Ph. D. - Publications

2013-2018 Pharmacology and Physiology Drexel University College of Medicine, Philadelphia, PA, United States 
 2018- Physiology and Cell Biology The Ohio State University College of Medicine 
Ion Channels, Intracellular Channels, Mitochondrial physiology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sengupta S, West KO, Sanghvi S, Laliotis G, Agosto LM, Lynch KW, Tsichlis PN, Singh H, Patrick KL, Guerau-de-Arellano M. PRMT5 Promotes Symmetric Dimethylation of RNA Processing Proteins and Modulates Activated T Cell Alternative Splicing and Ca/NFAT Signaling. Immunohorizons. 5: 884-897. PMID 34716181 DOI: 10.4049/immunohorizons.2100076  0.629
2021 Singh H. Mitochondrial Ion Channels in Cardiac Function. American Journal of Physiology. Cell Physiology. PMID 34550794 DOI: 10.1152/ajpcell.00246.2021  0.44
2021 Gałecka S, Kulawiak B, Bednarczyk P, Singh H, Szewczyk A. Single channel properties of mitochondrial large conductance potassium channel formed by BK-VEDEC splice variant. Scientific Reports. 11: 10925. PMID 34035423 DOI: 10.1038/s41598-021-90465-3  0.451
2020 Szteyn K, Singh H. BK Channels as Targets for Cardioprotection. Antioxidants (Basel, Switzerland). 9. PMID 32824463 DOI: 10.3390/Antiox9080760  0.824
2020 Sahni M, Yeboah B, Das P, Shah D, Ponnalagu D, Singh H, Nelin LD, Bhandari V. Novel biomarkers of bronchopulmonary dysplasia and bronchopulmonary dysplasia-associated pulmonary hypertension. Journal of Perinatology : Official Journal of the California Perinatal Association. PMID 32811975 DOI: 10.1038/S41372-020-00788-8  0.677
2020 Tombo N, Imam Aliagan AD, Feng Y, Singh H, Bopassa JC. Cardiac Ischemia/Reperfusion Stress Reduces Inner Mitochondrial Membrane Protein (Mitofilin) Levels During Early Reperfusion. Free Radical Biology & Medicine. PMID 32726689 DOI: 10.1016/J.Freeradbiomed.2020.06.039  0.742
2020 Ponnalagu D, Singh H. Insights Into the Role of Mitochondrial Ion Channels in Inflammatory Response. Frontiers in Physiology. 11: 258. PMID 32327997 DOI: 10.3389/Fphys.2020.00258  0.77
2020 Dougherty JA, Patel N, Kumar N, Rao SG, Angelos MG, Singh H, Cai C, Khan M. Human Cardiac Progenitor Cells Enhance Exosome Release and Promote Angiogenesis Under Physoxia. Frontiers in Cell and Developmental Biology. 8: 130. PMID 32211408 DOI: 10.3389/Fcell.2020.00130  0.577
2020 Gururaja Rao S, Patel NJ, Singh H. Intracellular Chloride Channels: Novel Biomarkers in Diseases. Frontiers in Physiology. 11: 96. PMID 32116799 DOI: 10.3389/Fphys.2020.00096  0.834
2020 Ponnalagu D, Bednarczyk P, Weist J, Gao E, Koch W, Khan M, Szewczyk AM, Singh H. Identification of Role of Mitochondrial Chloride Intracellular Channel (CLIC) Protein, CLIC4 and CLIC5 in Cardioprotection from IR Injury via Probably Modulating the Opening of MPTP Pore Biophysical Journal. 118: 446a. DOI: 10.1016/J.Bpj.2019.11.2495  0.792
2019 Ponnalagu D, Hussain AT, Thanawala R, Meka J, Bednarczyk P, Feng Y, Szewczyk A, GururajaRao S, Bopassa JC, Khan M, Singh H. Chloride channel blocker IAA-94 increases myocardial infarction by reducing calcium retention capacity of the cardiac mitochondria. Life Sciences. 116841. PMID 31494173 DOI: 10.1016/J.Lfs.2019.116841  0.836
2019 Gururaja Rao S, Bednarczyk P, Towheed A, Shah K, Karekar P, Ponnalagu D, Jensen HN, Addya S, Reyes BAS, Van Bockstaele EJ, Szewczyk A, Wallace DC, Singh H. BK () Channel Regulates Mitochondrial Function and Lifespan in . Cells. 8. PMID 31438578 DOI: 10.3390/Cells8090945  0.819
2019 Covarrubias R, Ismahil MA, Rokosh G, Hamid T, Accornero F, Singh H, Gumina RJ, Prabhu S, Bansal S. Optimized Protocols for Isolation, Fixation and Flow Cytometric Characterization of Leukocytes in Ischemic Hearts. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31373510 DOI: 10.1152/Ajpheart.00137.2019  0.345
2019 Leary S, Das P, Ponnalagu D, Singh H, Bhandari V. Genetic strain and sex differences in a hyperoxia-induced mouse model of varying severity of bronchopulmonary dysplasia. The American Journal of Pathology. PMID 30794808 DOI: 10.1016/J.Ajpath.2019.01.014  0.692
2019 Ponnalagu D, Hussain AT, Gao E, Singh H. Abstract 585: Role of Splice Variant Clic5B in Cardiac Mitochondrial Localization and Function Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.585  0.77
2018 Goswami SK, Ponnalagu D, Hussain AT, Shah K, Karekar P, Gururaja Rao S, Meredith AL, Khan M, Singh H. Expression and Activation of BK Channels in Mice Protects Against Ischemia-Reperfusion Injury of Isolated Hearts by Modulating Mitochondrial Function. Frontiers in Cardiovascular Medicine. 5: 194. PMID 30746365 DOI: 10.3389/Fcvm.2018.00194  0.799
2018 Sikder K, Shukla SK, Patel N, Singh H, Rafiq K. High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 48: 1317-1331. PMID 30048968 DOI: 10.1159/000492091  0.533
2018 Gururaja Rao S, Ponnalagu D, Patel NJ, Singh H. Three Decades of Chloride Intracellular Channel Proteins: From Organelle to Organ Physiology. Current Protocols in Pharmacology. 80: 11.21.1-11.21.17. PMID 30040212 DOI: 10.1002/Cpph.36  0.828
2018 Chaubey S, Thueson S, Ponnalagu D, Alam MA, Gheorghe CP, Aghai Z, Singh H, Bhandari V. Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6. Stem Cell Research & Therapy. 9: 173. PMID 29941022 DOI: 10.1186/S13287-018-0903-4  0.686
2018 Patel NH, Johannesen J, Shah K, Goswami SK, Patel NJ, Ponnalagu D, Kohut AR, Singh H. Inhibition of BK negatively alters cardiovascular function. Physiological Reports. 6: e13748. PMID 29932499 DOI: 10.14814/Phy2.13748  0.826
2018 Lam A, Karekar P, Shah K, Hariharan G, Fleyshman M, Kaur H, Singh H, Gururaja Rao S. Drosophila Voltage-Gated Calcium Channel α1-Subunits Regulate Cardiac Function in the Aging Heart. Scientific Reports. 8: 6910. PMID 29720608 DOI: 10.1038/S41598-018-25195-0  0.785
2018 Ponnalagu D, Patel NJ, Gao E, Koch WJ, Kohut AR, Singh H. Abstract 292: Mitochondrial CLIC4 and CLIC5B Mediate Cardio-protection From Ischemia/reperfusion Injury Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.292  0.798
2018 Singh S, Shah K, Wengrofsky A, Rao SG, Ponnalagu D, Kohut A, Singh H. ABSENCE OF LARGE CONDUCTANCE CALCIUM AND VOLTAGE ACTIVATED POTASSIUM CHANNEL CAUSES CARDIAC DYSFUNTION Journal of the American College of Cardiology. 71: A926. DOI: 10.1016/S0735-1097(18)31467-0  0.833
2017 Gururaja Rao S, Ponnalagu D, Sukur S, Singh H, Sanghvi S, Mei Y, Jin DJ, Singh H. Identification and Characterization of a Bacterial Homolog of Chloride Intracellular Channel (CLIC) Protein. Scientific Reports. 7: 8500. PMID 28819106 DOI: 10.1038/S41598-017-08742-Z  0.81
2017 Ponnalagu D, Tafsirul Hussain A, Gururaja Rao S, Singh H. An Alternative Splice Variant of Chloride Intracellular Channel 5 Protein, (CLIC5B) Regulates Cardiac Mitochondrial Localization and Function of CLIC5 Biophysical Journal. 112: 325a. DOI: 10.1016/J.Bpj.2016.11.1760  0.843
2016 Ponnalagu D, Singh H. Anion Channels of Mitochondria. Handbook of Experimental Pharmacology. PMID 27783269 DOI: 10.1007/164_2016_39  0.817
2016 Kohut A, Patel N, Singh H. Comprehensive Echocardiographic Assessment of the Right Ventricle in Murine Models. Journal of Cardiovascular Ultrasound. 24: 229-238. PMID 27721954 DOI: 10.4250/Jcu.2016.24.3.229  0.626
2016 Lee A, Lin A, Shah K, Singh H, Miller V, Gururaja Rao S. Optimization of Non-Thermal Plasma Treatment in an In Vivo Model Organism. Plos One. 11: e0160676. PMID 27505063 DOI: 10.1371/Journal.Pone.0160676  0.757
2016 Ponnalagu D, Rao SG, Farber J, Xin W, Hussain AT, Shah K, Tanda S, Berryman MA, Edwards JC, Singh H. Data supporting characterization of CLIC1, CLIC4, CLIC5 and DmCLIC antibodies and localization of CLICs in endoplasmic reticulum of cardiomyocytes. Data in Brief. 7: 1038-44. PMID 27104215 DOI: 10.1016/J.Dib.2016.03.061  0.828
2016 Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, ... ... Singh H, et al. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science Translational Medicine. 8: 334ra54. PMID 27075628 DOI: 10.1126/Scitranslmed.Aad3815  0.789
2016 Ponnalagu D, Rao SG, Farber J, Xin W, Hussain AT, Shah K, Tanda S, Berryman M, Edwards JC, Singh H. Molecular identity of cardiac mitochondrial chloride intracellular channel proteins. Mitochondrion. PMID 26777142 DOI: 10.1016/J.Mito.2016.01.001  0.859
2016 Singh H, Li M, Hall L, Chen S, Sukur S, Lu R, Caputo A, Meredith AL, Stefani E, Toro L. MaxiK Channel Interactome Reveals its Interaction with GABA Transporter 3 and Heat Shock Protein 60 in the Mammalian Brain. Neuroscience. PMID 26772433 DOI: 10.1016/J.Neuroscience.2015.12.058  0.829
2016 Patel N, Hussain A, Ponnalagu D, Edwards J, Kohut A, Singh H. LOSS OF CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4 PREVENTS CARDIAC HYPERTROPHY IN ISOPROTERENOL INDUCED PRESSURE OVERLOAD IN MOUSE MODELS Journal of the American College of Cardiology. 67: 1495. DOI: 10.1016/S0735-1097(16)31496-6  0.823
2016 Singh H, Ponnalagu D, Sukur S, Singh H, Ning Zhou Y, Jin DJ, Gururaja Rao S. A Bacterial Homolog of Chloride Intracellular Channel (CLIC) Protein Family, Stringent Starvation Protein A (SspA), forms a Non-Selective Ion Channel Biophysical Journal. 110: 117a. DOI: 10.1016/J.Bpj.2015.11.683  0.82
2016 Ponnalagu D, Gururaja Rao S, Bednarczyk P, Feng Y, Farber J, Thanawala R, Tafsirul Hussain A, Chrisostome Bopassa J, Szewczyk A, Singh H. Identification of Cardiac Mitochondrial Chloride Intracellular Channel (CLIC) Proteins and their Physiological Function Biophysical Journal. 110: 453a. DOI: 10.1016/J.Bpj.2015.11.2428  0.844
2015 Kabir ME, Singh H, Lu R, Olde B, Leeb-Lundberg LM, Bopassa JC. G Protein-Coupled Estrogen Receptor 1 Mediates Acute Estrogen-Induced Cardioprotection via MEK/ERK/GSK-3β Pathway after Ischemia/Reperfusion. Plos One. 10: e0135988. PMID 26356837 DOI: 10.1371/Journal.Pone.0135988  0.737
2015 Ponnalagu D, Farber J, Sukur S, Xin W, Gururaja Rao S, Singh H. Molecular Identity and Functional Characterization of Chloride Intracellular Channel (CLIC) Proteins in Cardiac Mitochondria Biophysical Journal. 108: 368a. DOI: 10.1016/J.Bpj.2014.11.2019  0.826
2015 Gururaja Rao S, Shah K, Singh G, Singh H. Ablation of BK Channels Impairs Mitochondria and affects Aging Biophysical Journal. 108: 280a. DOI: 10.1016/J.Bpj.2014.11.1532  0.821
2014 Toro L, Li M, Zhang Z, Singh H, Wu Y, Stefani E. MaxiK channel and cell signalling. Pflã¼Gers Archiv : European Journal of Physiology. 466: 875-86. PMID 24077696 DOI: 10.1007/S00424-013-1359-0  0.806
2013 Singh H, Lu R, Bopassa JC, Meredith AL, Stefani E, Toro L. MitoBK(Ca) is encoded by the Kcnma1 gene, and a splicing sequence defines its mitochondrial location. Proceedings of the National Academy of Sciences of the United States of America. 110: 10836-41. PMID 23754429 DOI: 10.1073/Pnas.1302028110  0.804
2013 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, et al. Response to Pomozi et al's research commentary. Circulation Research. 112: e152-3. PMID 23625949 DOI: 10.1161/Circresaha.113.301666  0.657
2013 Bopassa JC, Lu R, Singh H, Olde B, Leeb-Lundberg LF, Toro L, Stefani E. Identification of Mitochondrial Proteins regulated during Activation of GPER1-Leading to Cardioprotection Biophysical Journal. 104: 657a. DOI: 10.1016/J.Bpj.2012.11.3629  0.814
2013 Zhang Z, Singh H, Meredith A, Stefani E, Toro L. BK Gene Disruption Enhances Acute Renal Vascular Response to Angiotensin II Biophysical Journal. 104: 471a. DOI: 10.1016/J.Bpj.2012.11.2603  0.729
2013 Singh H, Hall LR, Chen SM, Meredith AL, Stefani E, Toro L. Maxik Interaction with Gaba Transporter 3 and Heat Shock Protein 60 in the Mouse Brain Biophysical Journal. 104: 366a-367a. DOI: 10.1016/J.Bpj.2012.11.2036  0.789
2012 Singh H, Stefani E, Toro L. Intracellular BK(Ca) (iBK(Ca)) channels. The Journal of Physiology. 590: 5937-47. PMID 22930268 DOI: 10.1113/Jphysiol.2011.215533  0.774
2012 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, et al. ABCC6 localizes to the mitochondria-associated membrane. Circulation Research. 111: 516-20. PMID 22811557 DOI: 10.1161/Circresaha.112.276667  0.684
2012 Singh H, Lu R, Rodríguez PF, Wu Y, Bopassa JC, Stefani E, Toro L. Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy. Mitochondrion. 12: 230-6. PMID 21982778 DOI: 10.1016/J.Mito.2011.09.004  0.804
2012 Bopassa JC, Lu R, Singh H, Olde B, Krust A, Leeb-Lundberg LF, Toro L, Stefani E. G-Protein Coupled Estrogen Receptor 1, but not Estrogen Receptors Alpha and Beta, Mediates Rapid Estrogen-Induced Cardioprotection during Ischemia/Reperfusion Injury in Male Mice Biophysical Journal. 102: 141a. DOI: 10.1016/J.Bpj.2011.11.775  0.795
2012 Rodríguez PFG, Wu Y, Zhao H, Singh H, Lu R, Li M, Zhang Z, Lee S, Toro L, Stefani E. A Custom-Built Fast Scanning STED Microscope with a Large Field of View Biophysical Journal. 102: 725. DOI: 10.1016/J.Bpj.2011.11.3935  0.779
2012 Bopassa JC, Singh H, Danesh SM, Meredith AL, Toro L, Stefani E. Kcnma1 Gene Expression Improves Mitochondrial Function in NS1619 Preconditioned Hearts after Ischemia/Reperfusion Injury Biophysical Journal. 102: 691a. DOI: 10.1016/J.Bpj.2011.11.3752  0.81
2012 Singh H, Hall LR, Meredith AL, Stefani E, Toro L. Analysis of MaxiK Channel Alpha-Subunit Subproteome from the Mouse Brain Biophysical Journal. 102: 690a-691a. DOI: 10.1016/J.Bpj.2011.11.3750  0.785
2012 Singh H, Lu R, Stefani E, Toro L. Targeting BKCa Channel to Mitochondria of Adult Cardiomyocytes Biophysical Journal. 102: 690a. DOI: 10.1016/J.Bpj.2011.11.3749  0.826
2011 Wu Y, Singh H, Lu R, Bopassa JC, Toro L, Stefani E. Quantification of Fluorescence Signals in Purified Mitochondria Biophysical Journal. 100: 141a. DOI: 10.1016/J.Bpj.2010.12.975  0.815
2011 Singh H, Felipe P, Rodríguez G, Lu R, Bopassa JC, Wu Y, Toro L, Stefani E. Superresolution Optical Microscopy of Isolated Cardiac Mitochondrial Proteins Biophysical Journal. 100: 619a. DOI: 10.1016/J.Bpj.2010.12.3564  0.789
2011 Bopassa JC, Singh H, Toro L, Stefani E. Gsk Mediates Rapid Estrogen-Induced Cardioprotection Without Akt Activation After Ischemia/Reperfusion Biophysical Journal. 100: 294a. DOI: 10.1016/J.Bpj.2010.12.1808  0.796
2011 Singh H, Lu R, Bopassa JC, Stefani E, Toro L. Molecular Characterization of BkCa Channel in Cardiac Mitochondria Biophysical Journal. 100: 250a. DOI: 10.1016/J.Bpj.2010.12.1582  0.837
2010 Singh H. Two decades with dimorphic Chloride Intracellular Channels (CLICs). Febs Letters. 584: 2112-21. PMID 20226783 DOI: 10.1016/J.Febslet.2010.03.013  0.48
2009 Singh H, Warburton S, Vondriska TM, Khakh BS. Proteomics to identify proteins interacting with P2X2 ligand-gated cation channels. Journal of Visualized Experiments : Jove. PMID 19455095 DOI: 10.3791/1178  0.439
2007 Singh H, Cousin MA, Ashley RH. Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin. The Febs Journal. 274: 6306-16. PMID 18028448 DOI: 10.1111/J.1742-4658.2007.06145.X  0.787
2007 Singh H, Ashley RH. CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels. Molecular Membrane Biology. 24: 41-52. PMID 17453412 DOI: 10.1080/09687860600927907  0.718
2006 Singh H, Ashley RH. Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore. Biophysical Journal. 90: 1628-38. PMID 16339885 DOI: 10.1529/Biophysj.105.072678  0.721
2004 Rainbow RD, James M, Hudman D, Al Johi M, Singh H, Watson PJ, Ashmole I, Davies NW, Lodwick D, Norman RI. Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels. The Biochemical Journal. 379: 173-81. PMID 14672537 DOI: 10.1042/BJ20031087  0.327
2003 Singh H, Hudman D, Lawrence CL, Rainbow RD, Lodwick D, Norman RI. Distribution of Kir6.0 and SUR2 ATP-sensitive potassium channel subunits in isolated ventricular myocytes. Journal of Molecular and Cellular Cardiology. 35: 445-59. PMID 12738227  0.386
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