Alon Friedman - Publications

Affiliations: 
Ben Gurion University, Safed, North District, Israel 

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vazana U, Schori L, Monsonego U, Swissa E, Pell GS, Roth Y, Brodt P, Friedman A, Prager O. TMS-Induced Controlled BBB Opening: Preclinical Characterization and Implications for Treatment of Brain Cancer. Pharmaceutics. 12. PMID 33027965 DOI: 10.3390/pharmaceutics12100946  0.52
2020 Kamintsky L, Beyea SD, Fisk JD, Hashmi JA, Omisade A, Calkin C, Bardouille T, Bowen C, Quraan M, Mitnitski A, Matheson K, Friedman A, Hanly JG. Blood-brain barrier leakage in systemic lupus erythematosus is associated with gray matter loss and cognitive impairment. Annals of the Rheumatic Diseases. PMID 33004325 DOI: 10.1136/annrheumdis-2020-218004  0.4
2020 Veksler R, Vazana U, Serlin Y, Prager O, Ofer J, Shemen N, Fisher AM, Minaeva O, Hua N, Saar-Ashkenazy R, Benou I, Riklin-Raviv T, Parker E, Mumby G, Kamintsky L, ... ... Friedman A, et al. Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players. Brain : a Journal of Neurology. PMID 32464655 DOI: 10.1093/brain/awaa140  0.96
2020 Schoknecht K, Kikhia M, Lemale CL, Liotta A, Lublinsky S, Mueller S, Boehm-Sturm P, Friedman A, Dreier JP. The role of spreading depolarizations and electrographic seizures in early injury progression of the rat photothrombosis stroke model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20915801. PMID 32241203 DOI: 10.1177/0271678X20915801  0.52
2020 Klein P, Friedman A, Hameed MQ, Kaminski RM, Bar-Klein G, Klitgaard H, Koepp M, Jozwiak S, Prince DA, Rotenberg A, Twyman R, Vezzani A, Wong M, Löscher W. Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? Epilepsia. 61: 359-386. PMID 32196665 DOI: 10.1111/epi.16450  0.6
2020 Swissa E, Bar-Klein G, Serlin Y, Weissberg I, Kamintsky L, Eisenkraft A, Statlender L, Shrot S, Rosman Y, Prager O, Friedman A. Midazolam and isoflurane combination reduces late brain damage in the paraoxon-induced status epilepticus rat model. Neurotoxicology. PMID 32084435 DOI: 10.1016/j.neuro.2020.02.007  0.6
2019 Milikovsky DZ, Ofer J, Senatorov VV, Friedman AR, Prager O, Sheintuch L, Elazari N, Veksler R, Zelig D, Weissberg I, Bar-Klein G, Swissa E, Hanael E, Ben-Arie G, Schefenbauer O, ... ... Friedman A, et al. Paroxysmal slow cortical activity in Alzheimer's disease and epilepsy is associated with blood-brain barrier dysfunction. Science Translational Medicine. 11. PMID 31801888 DOI: 10.1126/scitranslmed.aaw8954  0.96
2019 Senatorov VV, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, ... ... Friedman A, et al. Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction. Science Translational Medicine. 11. PMID 31801886 DOI: 10.1126/scitranslmed.aaw8283  0.96
2019 Kamintsky L, Cairns KA, Veksler R, Bowen C, Beyea SD, Friedman A, Calkin C. Blood-brain barrier imaging as a potential biomarker for bipolar disorder progression. Neuroimage. Clinical. 102049. PMID 31718955 DOI: 10.1016/j.nicl.2019.102049  0.4
2019 Swissa E, Serlin Y, Vazana U, Prager O, Friedman A. Blood-brain barrier dysfunction in status epileptics: Mechanisms and role in epileptogenesis. Epilepsy & Behavior : E&B. 106285. PMID 31711869 DOI: 10.1016/j.yebeh.2019.04.038  0.6
2019 Lublinsky S, Major S, Kola V, Horst V, Santos E, Platz J, Sakowitz O, Scheel M, Dohmen C, Graf R, Vatter H, Wolf S, Vajkoczy P, Shelef I, Woitzik J, ... ... Friedman A, et al. Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage. Ebiomedicine. 43: 460-472. PMID 31162113 DOI: 10.1016/j.ebiom.2019.04.054  0.4
2019 Hanael E, Veksler R, Friedman A, Bar-Klein G, Senatorov VV, Kaufer D, Konstantin L, Elkin M, Chai O, Peery D, Shamir MH. Blood-brain barrier dysfunction in canine epileptic seizures detected by dynamic contrast-enhanced magnetic resonance imaging. Epilepsia. 60: 1005-1016. PMID 31032909 DOI: 10.1111/epi.14739  0.96
2019 Serlin Y, Ofer J, Ben-Arie G, Veksler R, Ifergane G, Shelef I, Minuk J, Horev A, Friedman A. Blood-Brain Barrier Leakage. Stroke. 50: 1266-1269. PMID 31009340 DOI: 10.1161/STROKEAHA.119.025247  0.6
2019 Schindler L, Shaheen M, Saar-Ashkenazy R, Bani Odeh K, Sass SH, Friedman A, Kirschbaum C. Victims of War: Dehydroepiandrosterone Concentrations in Hair and Their Associations with Trauma Sequelae in Palestinian Adolescents Living in the West Bank. Brain Sciences. 9. PMID 30678071 DOI: 10.3390/brainsci9020020  0.48
2019 Prager O, Kamintsky L, Hasam-Henderson LA, Schoknecht K, Wuntke V, Papageorgiou I, Swolinsky J, Muoio V, Bar-Klein G, Vazana U, Heinemann U, Friedman A, Kovács R. Seizure-induced microvascular injury is associated with impaired neurovascular coupling and blood-brain barrier dysfunction. Epilepsia. PMID 30609012 DOI: 10.1111/epi.14631  0.68
2018 Rizzi M, Brandt C, Weissberg I, Milikovsky DZ, Pauletti A, Terrone G, Salamone A, Frigerio F, Löscher W, Friedman A, Vezzani A. Changes of dimension of EEG/ECoG nonlinear dynamics predict epileptogenesis and therapy outcomes. Neurobiology of Disease. 124: 373-378. PMID 30590177 DOI: 10.1016/j.nbd.2018.12.014  0.64
2018 Kovács R, Gerevich Z, Friedman A, Otáhal J, Prager O, Gabriel S, Berndt N. Bioenergetic Mechanisms of Seizure Control. Frontiers in Cellular Neuroscience. 12: 335. PMID 30349461 DOI: 10.3389/fncel.2018.00335  0.52
2018 Shaheen M, Schindler L, Saar-Ashkenazy R, Bani Odeh K, Soreq H, Friedman A, Kirschbaum C. Victims of war-Psychoendocrine evidence for the impact of traumatic stress on psychological well-being of adolescents growing up during the Israeli-Palestinian conflict. Psychophysiology. e13271. PMID 30101980 DOI: 10.1111/psyp.13271  0.84
2018 Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV, ... ... Friedman A, et al. Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. Brain : a Journal of Neurology. PMID 29360998 DOI: 10.1093/brain/awx350  0.96
2017 Lublinsky S, Kesler A, Friedman A, Horev A, Shelef I. Quantifying response to intracranial pressure normalization in idiopathic intracranial hypertension via dynamic neuroimaging. Journal of Magnetic Resonance Imaging : Jmri. PMID 28960686 DOI: 10.1002/jmri.25857  0.4
2017 Milakara D, Grozea C, Dahlem M, Major S, Winkler MKL, Lückl J, Scheel M, Kola V, Schoknecht K, Lublinsky S, Friedman A, Martus P, Hartings JA, Woitzik J, Dreier JP. Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage. Neuroimage. Clinical. 16: 524-538. PMID 28948141 DOI: 10.1016/j.nicl.2017.09.005  0.52
2017 Dreier JP, Lemale CL, Kola V, Friedman A, Schoknecht K. Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during stroke. Neuropharmacology. PMID 28941738 DOI: 10.1016/j.neuropharm.2017.09.027  0.52
2017 Schoknecht K, Berndt N, Rösner J, Heinemann U, Dreier JP, Kovács R, Friedman A, Liotta A. Event-Associated Oxygen Consumption Rate Increases ca. Five-Fold When Interictal Activity Transforms into Seizure-Like Events In Vitro. International Journal of Molecular Sciences. 18. PMID 28880249 DOI: 10.3390/ijms18091925  0.68
2017 Kim SY, Senatorov VV, Morrissey CS, Lippmann K, Vazquez O, Milikovsky DZ, Gu F, Parada I, Prince DA, Becker AJ, Heinemann U, Friedman A, Kaufer D. TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults. Scientific Reports. 7: 7711. PMID 28794441 DOI: 10.1038/s41598-017-07394-3  0.96
2017 Bekenstein U, Mishra N, Milikovsky DZ, Hanin G, Zelig D, Sheintuch L, Berson A, Greenberg DS, Friedman A, Soreq H. Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584127 DOI: 10.1073/pnas.1701201114  0.84
2017 Prager O, Friedman A, Nebenzahl YM. Role of neural barriers in the pathogenesis and outcome of Streptococcus pneumoniae meningitis. Experimental and Therapeutic Medicine. 13: 799-809. PMID 28450902 DOI: 10.3892/etm.2017.4082  0.44
2017 Bar-Klein G, Lublinsky S, Kamintsky L, Noyman I, Veksler R, Dalipaj H, Senatorov VV, Swissa E, Rosenbach D, Elazary N, Milikovsky DZ, Milk N, Kassirer M, Rosman Y, Serlin Y, ... ... Friedman A, et al. Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis. Brain : a Journal of Neurology. PMID 28444141 DOI: 10.1093/brain/awx073  0.96
2017 Milikovsky DZ, Weissberg I, Solomon-Kamintsky L, Lippmann K, Schefenbauer O, Frigerio F, Rizzi M, Sheintuch L, Zelig D, Ofer J, Vezzani A, Friedman A. Electrocorticographic dynamics as a novel biomarker in five models of epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28330876 DOI: 10.1523/JNEUROSCI.2446-16.2017  0.68
2016 Bar-Klein G, Klee R, Brandt C, Bankstahl M, Bascuñana P, Töllner K, Dalipaj H, Bankstahl JP, Friedman A, Löscher W. Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy. Annals of Neurology. PMID 27761920 DOI: 10.1002/ana.24804  0.6
2016 Rizzi M, Weissberg I, Milikovsky DZ, Friedman A. Corrigendum: Following a potential epileptogenic insult, prolonged high rates of nonlinear dynamical regimes of intermittency type is the hallmark of epileptogenesis. Scientific Reports. 6: 35510. PMID 27739508 DOI: 10.1038/srep35510  0.64
2016 Rizzi M, Weissberg I, Milikovsky DZ, Friedman A. Following a potential epileptogenic insult, prolonged high rates of nonlinear dynamical regimes of intermittency type is the hallmark of epileptogenesis. Scientific Reports. 6: 31129. PMID 27488140 DOI: 10.1038/srep31129  0.96
2016 Vazana U, Veksler R, Pell GS, Prager O, Fassler M, Chassidim Y, Roth Y, Shahar H, Zangen A, Raccah R, Onesti E, Ceccanti M, Colonnese C, Santoro A, Salvati M, ... ... Friedman A, et al. Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7727-39. PMID 27445149 DOI: 10.1523/JNEUROSCI.0587-16.2016  0.96
2016 Dreier JP, Fabricius M, Ayata C, Sakowitz OW, William Shuttleworth C, Dohmen C, Graf R, Vajkoczy P, Helbok R, Suzuki M, Schiefecker AJ, Major S, Winkler MK, Kang EJ, Milakara D, ... ... Friedman A, et al. Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27317657 DOI: 10.1177/0271678X16654496  0.68
2016 Pitkänen A, Löscher W, Vezzani A, Becker AJ, Simonato M, Lukasiuk K, Gröhn O, Bankstahl JP, Friedman A, Aronica E, Gorter JA, Ravizza T, Sisodiya SM, Kokaia M, Beck H. Advances in the development of biomarkers for epilepsy. The Lancet. Neurology. 15: 843-56. PMID 27302363 DOI: 10.1016/S1474-4422(16)00112-5  0.96
2016 Kim SY, Porter BE, Friedman A, Kaufer D. A potential role for glia-derived extracellular matrix remodeling in postinjury epilepsy. Journal of Neuroscience Research. PMID 27265805 DOI: 10.1002/jnr.23758  0.96
2016 Lippmann K, Kamintsky L, Kim SY, Lublinsky S, Prager O, Nichtweiss JF, Salar S, Kaufer D, Heinemann U, Friedman A. Epileptiform activity and spreading depolarization in the blood-brain barrier-disrupted peri-infarct hippocampus are associated with impaired GABAergic inhibition and synaptic plasticity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27252228 DOI: 10.1177/0271678X16652631  0.96
2016 Tiferet-Dweck C, Hensel M, Kirschbaum C, Tzelgov J, Friedman A, Salti M. Acute Stress and Perceptual Load Consume the Same Attentional Resources: A Behavioral-ERP Study. Plos One. 11: e0154622. PMID 27196027 DOI: 10.1371/journal.pone.0154622  0.96
2016 Salar S, Lapilover E, Müller J, Hollnagel JO, Lippmann K, Friedman A, Heinemann U. Synaptic plasticity in area CA1 of rat hippocampal slices following intraventricular application of albumin. Neurobiology of Disease. PMID 26972679 DOI: 10.1016/j.nbd.2016.03.008  0.96
2016 Serlin Y, Shafat T, Levy J, Winter A, Shneck M, Knyazer B, Parmet Y, Shalev H, Ur E, Friedman A. Angiographic evidence of proliferative retinopathy predicts neuropsychiatric morbidity in diabetic patients. Psychoneuroendocrinology. 67: 163-170. PMID 26907995 DOI: 10.1016/j.psyneuen.2016.02.009  0.96
2016 Saar-Ashkenazy R, Veksler R, Guez J, Jacob Y, Shelef I, Shalev H, Friedman A, Cohen JE. Breakdown of Inter-Hemispheric Connectivity Is Associated with Posttraumatic Symptomatology and Memory Impairment. Plos One. 11: e0144766. PMID 26863536 DOI: 10.1371/journal.pone.0144766  0.96
2015 Kaufer D, Friedman A, Seidman S, Soreq H. Corrigendum: Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature. PMID 26605528 DOI: 10.1038/nature16180  0.96
2015 Saar-Ashkenazy R, Shalev H, Kanthak MK, Guez J, Friedman A, Cohen JE. Altered processing of visual emotional stimuli in posttraumatic stress disorder: an event-related potential study. Psychiatry Research. 233: 165-74. PMID 26138281 DOI: 10.1016/j.pscychresns.2015.05.015  0.48
2015 Levy N, Milikovsky DZ, Baranauskas G, Vinogradov E, David Y, Ketzef M, Abutbul S, Weissberg I, Kamintsky L, Fleidervish I, Friedman A, Monsonego A. Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 26136430 DOI: 10.4049/jimmunol.1401446  0.96
2015 Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A, Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A, Verastegui M, Preux PM, Montano S, Pretell EJ, et al. In response: Multifactorial basis of epilepsy in patients with neurocysticercosis. Epilepsia. 56: 975-6. PMID 26040533 DOI: 10.1111/epi.12986  0.96
2015 Friedman A, Kaufer D. Blood-brain barrier in health and disease. Seminars in Cell & Developmental Biology. 38: 1. PMID 25868082 DOI: 10.1016/j.semcdb.2015.03.006  0.96
2015 Weissberg I, Wood L, Kamintsky L, Vazquez O, Milikovsky DZ, Alexander A, Oppenheim H, Ardizzone C, Becker A, Frigerio F, Vezzani A, Buckwalter MS, Huguenard JR, Friedman A, Kaufer D. Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction. Neurobiology of Disease. 78: 115-25. PMID 25836421 DOI: 10.1016/j.nbd.2015.02.029  0.96
2015 Serlin Y, Shelef I, Knyazer B, Friedman A. Anatomy and physiology of the blood-brain barrier. Seminars in Cell & Developmental Biology. 38: 2-6. PMID 25681530 DOI: 10.1016/j.semcdb.2015.01.002  0.96
2015 Gilad D, Shorer S, Ketzef M, Friedman A, Sekler I, Aizenman E, Hershfinkel M. Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures. Neurobiology of Disease. PMID 25562657 DOI: 10.1016/j.nbd.2014.12.020  0.96
2015 Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A, Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A, Verastegui M, Preux PM, Montano S, Pretell EJ, et al. Neurocysticercosis: A natural human model of epileptogenesis. Epilepsia. 56: 177-83. PMID 25534640 DOI: 10.1111/epi.12849  0.96
2015 Dreier JP, Reiffurth C, Woitzik J, Hartings JA, Drenckhahn C, Windler C, Friedman A, MacVicar B, Herreras O. How spreading depolarization can be the pathophysiological correlate of both migraine aura and stroke. Acta Neurochirurgica. Supplement. 120: 137-40. PMID 25366613 DOI: 10.1007/978-3-319-04981-6_23  0.96
2014 Sagy-Bross C, Kasianov K, Solomonov Y, Braiman A, Friedman A, Hadad N, Levy R. The role of cytosolic phospholipase A2 α in amyloid precursor protein induction by amyloid beta1-42 : implication for neurodegeneration. Journal of Neurochemistry. PMID 25533654 DOI: 10.1111/jnc.13012  0.96
2014 Veksler R, Shelef I, Friedman A. Blood-brain barrier imaging in human neuropathologies. Archives of Medical Research. 45: 646-52. PMID 25453223 DOI: 10.1016/j.arcmed.2014.11.016  0.96
2014 Weissberg I, Veksler R, Kamintsky L, Saar-Ashkenazy R, Milikovsky DZ, Shelef I, Friedman A. Imaging blood-brain barrier dysfunction in football players. Jama Neurology. 71: 1453-5. PMID 25383774 DOI: 10.1001/jamaneurol.2014.2682  0.96
2014 Bar-Klein G, Swissa E, Kamintsky L, Shekh-Ahmad T, Saar-Ashkenazy R, Hubary Y, Shrot S, Stetlander L, Eisenkraft A, Friedman A, Bialer M. sec-Butyl-propylacetamide (SPD) and two of its stereoisomers rapidly terminate paraoxon-induced status epilepticus in rats. Epilepsia. 55: 1953-8. PMID 25377630 DOI: 10.1111/epi.12838  0.96
2014 Friedman A, Bar-Klein G, Serlin Y, Parmet Y, Heinemann U, Kaufer D. Should losartan be administered following brain injury? Expert Review of Neurotherapeutics. 14: 1365-75. PMID 25346269 DOI: 10.1586/14737175.2014.972945  0.96
2014 Schoknecht K, Prager O, Vazana U, Kamintsky L, Harhausen D, Zille M, Figge L, Chassidim Y, Schellenberger E, Kovács R, Heinemann U, Friedman A. Monitoring stroke progression: in vivo imaging of cortical perfusion, blood-brain barrier permeability and cellular damage in the rat photothrombosis model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1791-801. PMID 25160672 DOI: 10.1038/jcbfm.2014.147  0.96
2014 Salar S, Maslarova A, Lippmann K, Nichtweiss J, Weissberg I, Sheintuch L, Kunz WS, Shorer Z, Friedman A, Heinemann U. Blood-brain barrier dysfunction can contribute to pharmacoresistance of seizures. Epilepsia. 55: 1255-63. PMID 24995798 DOI: 10.1111/epi.12713  0.96
2014 Shrot S, Ramaty E, Biala Y, Bar-Klein G, Daninos M, Kamintsky L, Makarovsky I, Statlender L, Rosman Y, Krivoy A, Lavon O, Kassirer M, Friedman A, Yaari Y. Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment. Toxicology. 323: 19-25. PMID 24881594 DOI: 10.1016/j.tox.2014.05.010  0.96
2014 Bar-Klein G, Cacheaux LP, Kamintsky L, Prager O, Weissberg I, Schoknecht K, Cheng P, Kim SY, Wood L, Heinemann U, Kaufer D, Friedman A. Losartan prevents acquired epilepsy via TGF-β signaling suppression. Annals of Neurology. 75: 864-75. PMID 24659129 DOI: 10.1002/ana.24147  0.96
2014 Saar-Ashkenazy R, Cohen JE, Guez J, Gasho C, Shelef I, Friedman A, Shalev H. Reduced corpus-callosum volume in posttraumatic stress disorder highlights the importance of interhemispheric connectivity for associative memory. Journal of Traumatic Stress. 27: 18-26. PMID 24473965 DOI: 10.1002/jts.21887  0.96
2014 Schoknecht K, Gabi S, Ifergane G, Friedman A, Shelef I. Detection of cerebral hyperperfusion syndrome after carotid endarterectomy with CT perfusion. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 24: 295-7. PMID 23163877 DOI: 10.1111/j.1552-6569.2012.00773.x  0.96
2013 Fassler M, Weissberg I, Levy N, Diaz-Griffero F, Monsonego A, Friedman A, Taube R. Preferential lentiviral targeting of astrocytes in the central nervous system. Plos One. 8: e76092. PMID 24098426 DOI: 10.1371/journal.pone.0076092  0.96
2013 Chai O, Sommer A, Zimmerman G, Soreq H, Friedman A, Bdolah-Abram T, Aroch I, Shamir MH. Acetylcholinesterase activity in the cerebrospinal fluid of dogs with seizures. Veterinary Journal (London, England : 1997). 198: 292-4. PMID 23988333 DOI: 10.1016/j.tvjl.2013.06.027  0.96
2013 Serlin Y, Tal G, Chassidim Y, Parmet Y, Tomkins O, Knyazer B, Friedman A, Levy J. Novel fluorescein angiography-based computer-aided algorithm for assessment of retinal vessel permeability. Plos One. 8: e61599. PMID 23626701 DOI: 10.1371/journal.pone.0061599  0.96
2013 Maslarova A, Salar S, Lapilover E, Friedman A, Veh RW, Heinemann U. Increased susceptibility to acetylcholine in the entorhinal cortex of pilocarpine-treated rats involves alterations in KCNQ channels. Neurobiology of Disease. 56: 14-24. PMID 23583611 DOI: 10.1016/j.nbd.2013.02.016  0.96
2013 Chassidim Y, Veksler R, Lublinsky S, Pell GS, Friedman A, Shelef I. Quantitative imaging assessment of blood-brain barrier permeability in humans. Fluids and Barriers of the Cns. 10: 9. PMID 23388348 DOI: 10.1186/2045-8118-10-9  0.96
2013 Schmitz AK, Grote A, Raabe A, Urbach H, Friedman A, von Lehe M, Becker AJ, Niehusmann P. Albumin storage in neoplastic astroglial elements of gangliogliomas. Seizure. 22: 144-50. PMID 23182422 DOI: 10.1016/j.seizure.2012.10.014  0.96
2013 Vezzani A, Friedman A, Dingledine RJ. The role of inflammation in epileptogenesis. Neuropharmacology. 69: 16-24. PMID 22521336 DOI: 10.1016/j.neuropharm.2012.04.004  0.96
2013 Cohen JE, Shalev H, Admon R, Hefetz S, Gasho CJ, Shachar LJ, Shelef I, Hendler T, Friedman A. Emotional brain rhythms and their impairment in post-traumatic patients. Human Brain Mapping. 34: 1344-56. PMID 22331598 DOI: 10.1002/hbm.21516  0.96
2012 Winkler MK, Chassidim Y, Lublinsky S, Revankar GS, Major S, Kang EJ, Oliveira-Ferreira AI, Woitzik J, Sandow N, Scheel M, Friedman A, Dreier JP. Impaired neurovascular coupling to ictal epileptic activity and spreading depolarization in a patient with subarachnoid hemorrhage: possible link to blood-brain barrier dysfunction. Epilepsia. 53: 22-30. PMID 23134492 DOI: 10.1111/j.1528-1167.2012.03699.x  0.96
2012 Abbott NJ, Friedman A. Overview and introduction: the blood-brain barrier in health and disease. Epilepsia. 53: 1-6. PMID 23134489 DOI: 10.1111/j.1528-1167.2012.03696.x  0.96
2012 Frigerio F, Frasca A, Weissberg I, Parrella S, Friedman A, Vezzani A, Noé FM. Long-lasting pro-ictogenic effects induced in vivo by rat brain exposure to serum albumin in the absence of concomitant pathology. Epilepsia. 53: 1887-97. PMID 22984896 DOI: 10.1111/j.1528-1167.2012.03666.x  0.96
2012 Braganza O, Bedner P, Hüttmann K, von Staden E, Friedman A, Seifert G, Steinhäuser C. Albumin is taken up by hippocampal NG2 cells and astrocytes and decreases gap junction coupling. Epilepsia. 53: 1898-906. PMID 22967085 DOI: 10.1111/j.1528-1167.2012.03665.x  0.96
2012 Pavlovsky L, Bitan Y, Shalev H, Serlin Y, Friedman A. Stress-induced altered cholinergic-glutamatergic interactions in the mouse hippocampus. Brain Research. 1472: 99-106. PMID 22796599 DOI: 10.1016/j.brainres.2012.05.057  0.96
2012 Levi H, Schoknecht K, Prager O, Chassidim Y, Weissberg I, Serlin Y, Friedman A. Stimulation of the sphenopalatine ganglion induces reperfusion and blood-brain barrier protection in the photothrombotic stroke model. Plos One. 7: e39636. PMID 22745798 DOI: 10.1371/journal.pone.0039636  0.96
2012 Ofek K, Schoknecht K, Melamed-Book N, Heinemann U, Friedman A, Soreq H. Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling. Journal of Cellular and Molecular Medicine. 16: 2736-44. PMID 22697296 DOI: 10.1111/j.1582-4934.2012.01596.x  0.96
2012 Dedeurwaerdere S, Friedman A, Fabene PF, Mazarati A, Murashima YL, Vezzani A, Baram TZ. Finding a better drug for epilepsy: antiinflammatory targets. Epilepsia. 53: 1113-8. PMID 22691043 DOI: 10.1111/j.1528-1167.2012.03520.x  0.96
2012 Gnatek Y, Zimmerman G, Goll Y, Najami N, Soreq H, Friedman A. Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis. Frontiers in Molecular Neuroscience. 5: 66. PMID 22639569 DOI: 10.3389/fnmol.2012.00066  0.96
2012 Berson A, Barbash S, Shaltiel G, Goll Y, Hanin G, Greenberg DS, Ketzef M, Becker AJ, Friedman A, Soreq H. Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. Embo Molecular Medicine. 4: 730-42. PMID 22628224 DOI: 10.1002/emmm.201100995  0.96
2012 Stanimirovic DB, Friedman A. Pathophysiology of the neurovascular unit: disease cause or consequence? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1207-21. PMID 22395208 DOI: 10.1038/jcbfm.2012.25  0.96
2012 Heinemann U, Kaufer D, Friedman A. Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy. Glia. 60: 1251-7. PMID 22378298 DOI: 10.1002/glia.22311  0.96
2012 Raabe A, Schmitz AK, Pernhorst K, Grote A, von der Brelie C, Urbach H, Friedman A, Becker AJ, Elger CE, Niehusmann P. Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions. Epilepsia. 53: 539-48. PMID 22372630 DOI: 10.1111/j.1528-1167.2012.03405.x  0.96
2011 Weissberg I, Reichert A, Heinemann U, Friedman A. Blood-brain barrier dysfunction in epileptogenesis of the temporal lobe. Epilepsy Research and Treatment. 2011: 143908. PMID 22937228 DOI: 10.1155/2011/143908  0.68
2011 Vezzani A, Friedman A. Brain inflammation as a biomarker in epilepsy. Biomarkers in Medicine. 5: 607-14. PMID 22003909 DOI: 10.2217/bmm.11.61  0.96
2011 Friedman A. Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: a puzzle of a chicken and egg? Epilepsia. 52: 19-20. PMID 21967353 DOI: 10.1111/j.1528-1167.2011.03227.x  0.96
2011 Friedman A, Kaufer D. Blood-brain barrier breakdown and blood-brain communication in neurological and psychiatric diseases. Cardiovascular Psychiatry and Neurology. 2011: 431470. PMID 21747970 DOI: 10.1155/2011/431470  0.96
2011 Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH, et al. Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. The Journal of Biological Chemistry. 286: 30022-33. PMID 21705317 DOI: 10.1074/jbc.M111.261206  0.96
2011 Friedman A, Dingledine R. Molecular cascades that mediate the influence of inflammation on epilepsy. Epilepsia. 52: 33-9. PMID 21542844 DOI: 10.1111/j.1528-1167.2011.03034.x  0.96
2011 Tomkins O, Feintuch A, Benifla M, Cohen A, Friedman A, Shelef I. Blood-brain barrier breakdown following traumatic brain injury: a possible role in posttraumatic epilepsy. Cardiovascular Psychiatry and Neurology. 2011: 765923. PMID 21436875 DOI: 10.1155/2011/765923  0.96
2010 Shlosberg D, Benifla M, Kaufer D, Friedman A. Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nature Reviews. Neurology. 6: 393-403. PMID 20551947 DOI: 10.1038/nrneurol.2010.74  0.96
2010 Ivens S, Gabriel S, Greenberg G, Friedman A, Shelef I. Blood-brain barrier breakdown as a novel mechanism underlying cerebral hyperperfusion syndrome Journal of Neurology. 257: 615-620. PMID 20361293 DOI: 10.1007/s00415-009-5384-z  0.96
2010 Sifringer M, Brait D, Weichelt U, Zimmerman G, Endesfelder S, Brehmer F, von Haefen C, Friedman A, Soreq H, Bendix I, Gerstner B, Felderhoff-Mueser U. Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain. Brain, Behavior, and Immunity. 24: 792-9. PMID 19729061 DOI: 10.1016/j.bbi.2009.08.010  0.96
2010 Prager O, Chassidim Y, Klein C, Levi H, Shelef I, Friedman A. Dynamic in vivo imaging of cerebral blood flow and blood-brain barrier permeability. Neuroimage. 49: 337-44. PMID 19682584 DOI: 10.1016/j.neuroimage.2009.08.009  0.96
2009 Shalev H, Serlin Y, Friedman A. Breaching the blood-brain barrier as a gate to psychiatric disorder. Cardiovascular Psychiatry and Neurology. 2009: 278531. PMID 19936105 DOI: 10.1155/2009/278531  0.6
2009 David Y, Cacheaux LP, Ivens S, Lapilover E, Heinemann U, Kaufer D, Friedman A. Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10588-99. PMID 19710312 DOI: 10.1523/JNEUROSCI.2323-09.2009  0.96
2009 Cacheaux LP, Ivens S, David Y, Lakhter AJ, Bar-Klein G, Shapira M, Heinemann U, Friedman A, Kaufer D. Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8927-35. PMID 19605630 DOI: 10.1523/JNEUROSCI.0430-09.2009  0.96
2009 Friedman A, Kaufer D, Heinemann U. Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy. Epilepsy Research. 85: 142-9. PMID 19362806 DOI: 10.1016/j.eplepsyres.2009.03.005  0.96
2008 Zimmerman G, Njunting M, Ivens S, Tolner EA, Tolner E, Behrens CJ, Gross M, Soreq H, Heinemann U, Friedman A. Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats. The European Journal of Neuroscience. 27: 965-75. PMID 18333967 DOI: 10.1111/j.1460-9568.2008.06070.x  0.96
2007 Friedman A, Behrens CJ, Heinemann U. Cholinergic dysfunction in temporal lobe epilepsy. Epilepsia. 48: 126-30. PMID 17910592 DOI: 10.1111/j.1528-1167.2007.01300.x  0.96
2007 Pavlovsky L, Friedman A. Pathogenesis of stress-associated skin disorders: exploring the brain-skin axis. Current Problems in Dermatology. 35: 136-45. PMID 17641495 DOI: 10.1159/0000106420  0.96
2007 Ivens S, Kaufer D, Flores LP, Bechmann I, Zumsteg D, Tomkins O, Seiffert E, Heinemann U, Friedman A. TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis. Brain : a Journal of Neurology. 130: 535-47. PMID 17121744 DOI: 10.1093/brain/awl317  0.96
2006 Zumsteg D, Friedman A, Wieser HG, Wennberg RA. Propagation of interictal discharges in temporal lobe epilepsy: correlation of spatiotemporal mapping with intracranial foramen ovale electrode recordings. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 117: 2615-26. PMID 17029950 DOI: 10.1016/j.clinph.2006.07.319  0.96
2006 Browne RO, Moyal-Segal LB, Zumsteg D, David Y, Kofman O, Berger A, Soreq H, Friedman A. Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1733-5. PMID 16807370 DOI: 10.1096/fj.05-5576fje  0.96
2006 Kofman O, Berger A, Massarwa A, Friedman A, Jaffar AA. Motor inhibition and learning impairments in school-aged children following exposure to organophosphate pesticides in infancy. Pediatric Research. 60: 88-92. PMID 16788088 DOI: 10.1203/01.pdr.0000219467.47013.35  0.96
2006 Zumsteg D, Friedman A, Wieser HG, Wennberg RA. Source localization of interictal epileptiform discharges: comparison of three different techniques to improve signal to noise ratio. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 117: 562-71. PMID 16427355 DOI: 10.1016/j.clinph.2005.11.014  0.96
2005 Zumsteg D, Friedman A, Wennberg RA, Wieser HG. Source localization of mesial temporal interictal epileptiform discharges: correlation with intracranial foramen ovale electrode recordings. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 116: 2810-8. PMID 16253551 DOI: 10.1016/j.clinph.2005.08.009  0.96
2005 Behrens CJ, van den Boom LP, de Hoz L, Friedman A, Heinemann U. Induction of sharp wave-ripple complexes in vitro and reorganization of hippocampal networks. Nature Neuroscience. 8: 1560-7. PMID 16222227 DOI: 10.1038/nn1571  0.96
2005 Korn A, Golan H, Melamed I, Pascual-Marqui R, Friedman A. Focal cortical dysfunction and blood-brain barrier disruption in patients with Postconcussion syndrome. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 22: 1-9. PMID 15689708 DOI: 10.1097/01.WNP.0000150973.24324.A7  0.96
2005 Pavlovsky L, Seiffert E, Heinemann U, Korn A, Golan H, Friedman A. Persistent BBB disruption may underlie alpha interferon-induced seizures. Journal of Neurology. 252: 42-6. PMID 15672209 DOI: 10.1007/s00415-005-0596-3  0.96
2005 Benmoyal-Segal L, Vander T, Shifman S, Bryk B, Ebstein RP, Marcus EL, Stessman J, Darvasi A, Herishanu Y, Friedman A, Soreq H. Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 452-4. PMID 15629887 DOI: 10.1096/fj.04-2106fje  0.96
2004 Seiffert E, Dreier JP, Ivens S, Bechmann I, Tomkins O, Heinemann U, Friedman A. Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7829-36. PMID 15356194 DOI: 10.1523/JNEUROSCI.1751-04.2004  0.96
2003 Wieser HG, Ortega M, Friedman A, Yonekawa Y. Long-term seizure outcomes following amygdalohippocampectomy. Journal of Neurosurgery. 98: 751-63. PMID 12691400 DOI: 10.3171/jns.2003.98.4.0751  0.96
2003 Pavlovsky L, Browne RO, Friedman A. Pyridostigmine enhances glutamatergic transmission in hippocampal CA1 neurons. Experimental Neurology. 179: 181-7. PMID 12618125 DOI: 10.1016/S0014-4886(02)00016-X  0.96
2002 Meshorer E, Erb C, Gazit R, Pavlovsky L, Kaufer D, Friedman A, Glick D, Ben-Arie N, Soreq H. Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (New York, N.Y.). 295: 508-12. PMID 11799248 DOI: 10.1126/science.1066752  0.96
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