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Przemyslaw Radwanski, Ph.D. - Publications

Affiliations: 
2010 Pharmacology and Toxicology University of Utah, Salt Lake City, UT 
Area:
Pharmacology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Struckman HL, Moise N, King DR, Soltisz A, Buxton A, Dunlap I, Chen Z, Radwański PB, Weinberg SH, Veeraraghavan R. Unraveling Impacts of Chamber-Specific Differences in Intercalated Disc Ultrastructure and Molecular Organization on Cardiac Conduction. Jacc. Clinical Electrophysiology. PMID 37498248 DOI: 10.1016/j.jacep.2023.05.042  0.608
2023 Struckman HL, Moise N, King DR, Soltisz A, Buxton A, Dunlap I, Chen Z, Radwański PB, Weinberg SH, Veeraraghavan R. Unraveling Chamber-specific Differences in Intercalated Disc Ultrastructure and Molecular Organization and Their Impact on Cardiac Conduction. Biorxiv : the Preprint Server For Biology. PMID 36824727 DOI: 10.1101/2023.02.13.528369  0.621
2023 Tarasov M, Struckman HL, Olgar Y, Miller A, Demirtas M, Bogdanov V, Terentyeva R, Soltisz AM, Meng X, Min D, Sakuta G, Dunlap I, Duran AD, Foster MP, Davis JP, et al. NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling. The Journal of Clinical Investigation. PMID 36821382 DOI: 10.1172/JCI152071  0.659
2022 Mezache L, Nuovo GJ, Suster D, Tili E, Awad H, Radwański PB, Veeraraghavan R. Histologic, viral, and molecular correlates of heart disease in fatal COVID-19. Annals of Diagnostic Pathology. 60: 151983. PMID 35660807 DOI: 10.1016/j.anndiagpath.2022.151983  0.605
2020 Mezache L, Struckman HL, Greer-Short A, Baine S, Györke S, Radwański PB, Hund TJ, Veeraraghavan R. Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling. Scientific Reports. 10: 20463. PMID 33235263 DOI: 10.1038/s41598-020-77562-5  0.632
2020 Baine S, Thomas J, Bonilla IM, Ivanova M, Belevych A, Li J, Veeraraghavan R, Radwanski PB, Carnes CA, Gyorke S. Muscarinic-dependent phosphorylation of the cardiac ryanodine receptor by protein kinase G is mediated by PI3K-AKT-nNOS signaling. The Journal of Biological Chemistry. PMID 32580946 DOI: 10.1074/Jbc.Ra120.014054  0.575
2020 Munger MA, Olğar Y, Koleske ML, Struckman HL, Mandrioli J, Lou Q, Bonila I, Kim K, Ramos Mondragon R, Priori SG, Volpe P, Valdivia HH, Biskupiak J, Carnes CA, Veeraraghavan R, et al. Tetrodotoxin-Sensitive Neuronal-Type Na Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation. Journal of the American Heart Association. e015119. PMID 32468902 DOI: 10.1161/Jaha.119.015119  0.684
2020 Struckman HL, Baine S, Thomas J, Mezache L, Mykytyn K, Györke S, Radwański PB, Veeraraghavan R. Super-Resolution Imaging Using a Novel High-Fidelity Antibody Reveals Close Association of the Neuronal Sodium Channel Na1.6 with Ryanodine Receptors in Cardiac Muscle. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 1-9. PMID 31931893 DOI: 10.1017/S1431927619015289  0.618
2020 Olgar Y, Miler A, Struckman H, Veeraraghavan R, Radwanski P. Multiscale, Multimodal Imaging of Structure and Function Reveals Mechanisms of Normal and Abnormal Cardiac Physiology Microscopy and Microanalysis. 1-2. DOI: 10.1017/S1431927620016025  0.628
2020 Mezache L, Struckman H, Phillipsa A, Baine S, Greer-Short A, Gyorke S, Radwanski P, Hund T, Veeraraghavan R. Indirect CLEM – from Structural Insights to Novel Therapy for Atrial Fibrillation Microscopy and Microanalysis. 1-2. DOI: 10.1017/S1431927620015196  0.6
2020 Struckman HL, Mezache L, Phillips A, Dagher C, Greer-Short A, Radwanski P, Hund TJ, Veeraraghavan R. Differential Impact of Selective De-adhesion within NaV1.5-rich Intercalated Disk Nanodomains on Atrial Arrhythmia Risk Biophysical Journal. 118: 100a. DOI: 10.1016/J.Bpj.2019.11.704  0.578
2020 Olgar Y, Gyorke S, Veeraraghavan R, Davis JP, Radwanski P. A Calmodulin Mutation that Dysregulates NaV1.6 But Not NaV1.5 Biophysical Journal. 118: 576a. DOI: 10.1016/J.Bpj.2019.11.3129  0.538
2020 Mezache L, Struckman H, Phillips A, Baine S, Greer-Short A, Gyorke S, Radwanski P, Hund TJ, Veeraraghavan R. The Vascular Barrier Regulates Cardiac Nanodomains: Implications for the Genesis of Atrial Fibrillation Biophysical Journal. 118: 463a. DOI: 10.1016/J.Bpj.2019.11.2573  0.665
2020 Bonilla IM, Baine S, Stepanov A, Li J, Belevych AE, Radwanski P, Volpe P, Priori S, Terentyev DA, Gyorke S. SOCE Contributes to Normal Calcium Homeostasis and Rythmic Activity of Atrial Myocardium Biophysical Journal. 118: 406a. DOI: 10.1016/J.Bpj.2019.11.2300  0.337
2020 Hamilton S, Terentyeva R, Li J, Stepanov A, Bonilla IM, Knollmann BC, Radwanski P, Gyorke S, Belevych AE, Terentyev D. Hyperactivity of RyR2 in Cardiac Disease is Exacerbated by Calcium Leak-Induced Mitochondrial ROS Biophysical Journal. 118: 255a-256a. DOI: 10.1016/J.Bpj.2019.11.1489  0.335
2019 Bonilla IM, Belevych AE, Baine S, Stepanov A, Mezache L, Bodnar T, Liu B, Volpe P, Priori S, Weisleder N, Sakuta G, Carnes CA, Radwański PB, Veeraraghavan R, Gyorke S. Enhancement of Cardiac Store Operated Calcium Entry (SOCE) within Novel Intercalated Disk Microdomains in Arrhythmic Disease. Scientific Reports. 9: 10179. PMID 31308393 DOI: 10.1038/S41598-019-46427-X  0.687
2019 Mezache L, Struckman H, Greer-Short A, Phillips A, Martinson A, Thomas J, Radwanski P, Hund TJ, Veeraraghavan R. Vegf-Induced Vascular Leak Promotes Atrial Fibrillation by Disrupting Intercalated Disc Nanodomains Biophysical Journal. 116: 32a. DOI: 10.1016/J.Bpj.2018.11.212  0.602
2019 Mercado IMB, Belevych A, Baine S, Bodnar T, Liu B, Radwanski P, Veeraraghavan R, Volpe P, Priori S, Weisleder N, Gyorke S. Cardiac Store Operated Calcium Entry (SOCE) is Compartmentalized at Intercalated Disks and Linked to Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) Biophysical Journal. 116: 236a. DOI: 10.1016/J.Bpj.2018.11.1297  0.398
2018 Radwański PB, Johnson CN, Györke S, Veeraraghavan R. Cardiac Arrhythmias as Manifestations of Nanopathies: An Emerging View. Frontiers in Physiology. 9: 1228. PMID 30233404 DOI: 10.3389/Fphys.2018.01228  0.632
2018 Koleske M, Bonilla I, Thomas J, Zaman N, Baine S, Knollmann BC, Veeraraghavan R, Györke S, Radwański PB. Tetrodotoxin-sensitive Nas contribute to early and delayed afterdepolarizations in long QT arrhythmia models. The Journal of General Physiology. PMID 29793933 DOI: 10.1085/Jgp.201711909  0.655
2018 Radwanski P, Davis J, Gyorke S. Enhanced Tetrodotoxin-Sensitive Neuronal Na+ Channel Activity Associated with Arrhythmogenic Calmodulin Mutation N98S Biophysical Journal. 114: 631a. DOI: 10.1016/J.Bpj.2017.11.3412  0.309
2017 Veeraraghavan R, Radwański PB. Sodium channel clusters: harmonizing the cardiac conduction orchestra. The Journal of Physiology. PMID 29266288 DOI: 10.1113/Jp275632  0.574
2017 Györke S, Belevych AE, Liu B, Kubasov IV, Carnes CA, Radwański PB. The role of luminal Ca regulation in Ca signaling refractoriness and cardiac arrhythmogenesis. The Journal of General Physiology. PMID 28798279 DOI: 10.1085/jgp.201711808  0.364
2017 Veeraraghavan R, Györke S, Radwański PB. Neuronal sodium channels: emerging components of the nano-machinery of cardiac calcium cycling. The Journal of Physiology. PMID 28195313 DOI: 10.1113/Jp273058  0.681
2016 Radwański PB, Ho HT, Veeraraghavan R, Brunello L, Liu B, Belevych AE, Unudurthi SD, Makara MA, Priori SG, Volpe P, Armoundas AA, Dillmann WH, Knollmann BC, Mohler PJ, Hund TJ, et al. Neuronal Na(+) Channels Are Integral Components of Pro-arrhythmic Na(+)/Ca(2+) Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-adrenergic Stimulation. Jacc. Basic to Translational Science. 1: 251-266. PMID 27747307 DOI: 10.1016/J.Jacbts.2016.04.004  0.668
2016 Ho HT, Belevych AE, Liu B, Bonilla IM, Radwański PB, Kubasov IV, Valdivia HH, Schober K, Carnes CA, Györke S. Muscarinic Stimulation Facilitates Sarcoplasmic Reticulum Ca Release by Modulating Ryanodine Receptor 2 Phosphorylation Through Protein Kinase G and Ca/Calmodulin-Dependent Protein Kinase II. Hypertension (Dallas, Tex. : 1979). PMID 27647848 DOI: 10.1161/HYPERTENSIONAHA.116.07666  0.31
2016 Radwanski P, Ho H, Knollmann B, Belevych A, Gyorke S. Late Na+ Current Contributes to Arrhythmogenic Diastolic Ca2+ release in catecholaminergic polymorphic ventricular tachycardia (CPVT) The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.1274.3  0.447
2016 Radwański PB, Ho H, Liu B, Belevych A, Armoundas A, Dillmann W, Knollmann B, Mohler P, Hund T, Györke S. Catecholaminergic Stimulation of Neuronal Na+ Channels Accounts for Triggered Arrhythmia Mechanism in CPVT Biophysical Journal. 110: 435a. DOI: 10.1016/J.Bpj.2015.11.2348  0.351
2016 Walton SD, Ho H, Elizaga NM, Siddiqui JK, O'Neil AJ, Neilson NA, Belevych A, Liu B, Radwanski P, Gyorke S, Davis JP. Engineering an Anti-Arrhythmic Calmodulin Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1204  0.4
2014 Lou Q, Liu B, Belevych AE, Radwanski P, Kalyanasundaram A, Dillmann WH, Armoundas AA, Knollmann BC, Fedorov VV, Györke S. Subcellular Origin and Tissue-Wide Synchronization of Abnormal Ca Release in the Genesis of Ca-Dependent Atrial Arrhythmia Biophysical Journal. 106: 431a. DOI: 10.1016/J.Bpj.2013.11.2429  0.477
2013 Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Györke S. Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 110: 10312-7. PMID 23733959 DOI: 10.1073/Pnas.1300052110  0.442
2013 Belevych AE, Radwański PB, Carnes CA, Györke S. 'Ryanopathy': causes and manifestations of RyR2 dysfunction in heart failure. Cardiovascular Research. 98: 240-7. PMID 23408344 DOI: 10.1093/cvr/cvt024  0.405
2013 Radwański PB, Belevych AE, Brunello L, Carnes CA, Györke S. Store-dependent deactivation: cooling the chain-reaction of myocardial calcium signaling. Journal of Molecular and Cellular Cardiology. 58: 77-83. PMID 23108187 DOI: 10.1016/j.yjmcc.2012.10.008  0.344
2013 Radwański PB, Greer-Short A, Poelzing S. Inhibition of Na+ channels ameliorates arrhythmias in a drug-induced model of Andersen-Tawil syndrome. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 255-63. PMID 23041575 DOI: 10.1016/J.Hrthm.2012.10.005  0.663
2011 Radwański PB, Poelzing S. NCX is an important determinant for premature ventricular activity in a drug-induced model of Andersen-Tawil syndrome. Cardiovascular Research. 92: 57-66. PMID 21697145 DOI: 10.1093/Cvr/Cvr180  0.637
2010 Radwański PB, Veeraraghavan R, Poelzing S. Cytosolic calcium accumulation and delayed repolarization associated with ventricular arrhythmias in a guinea pig model of Andersen-Tawil syndrome. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 1428-1435.e1. PMID 20380896 DOI: 10.1016/J.Hrthm.2010.03.044  0.725
2008 Van Tassell BW, Radwanski P, Movsesian M, Munger MA. Combination therapy with beta-adrenergic receptor antagonists and phosphodiesterase inhibitors for chronic heart failure. Pharmacotherapy. 28: 1523-30. PMID 19025433 DOI: 10.1592/Phco.28.12.1523  0.342
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