David J. Linden - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cellular electrophysiology

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang W, Chuang YA, Na Y, Ye Z, Yang L, Lin R, Zhou J, Wu J, Qiu J, Savonenko A, Leahy DJ, Huganir R, Linden DJ, Worley PF. Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation. Molecular Cell. PMID 31151856 DOI: 10.1016/j.molcel.2019.05.004  1
2019 Ye Z, Cudmore RH, Linden DJ. Estrogen-Dependent Functional Spine Dynamics in Neocortical Pyramidal Neurons of the Mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30992373 DOI: 10.1523/JNEUROSCI.2772-18.2019  1
2017 Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B. In Vivo Imaging of CNS Injury and Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 10808-10816. PMID 29118209 DOI: 10.1523/JNEUROSCI.1826-17.2017  0.92
2017 Ryu C, Jang DC, Jung D, Kim YG, Shim HG, Ryu HH, Lee YS, Linden DJ, Worley PF, Kim SJ. STIM1 regulates somatic Ca(2+) signals and intrinsic firing properties of cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821659 DOI: 10.1523/JNEUROSCI.3973-16.2017  0.96
2017 Shevelkin AV, Terrillion CE, Abazyan BN, Kajstura TJ, Jouroukhin YA, Rudow GL, Troncoso JC, Linden DJ, Pletnikov MV. Corrigendum to "Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice" [Neurobiol. Dis. 103 (2017) 144-153]. Neurobiology of Disease. PMID 28800926 DOI: 10.1016/j.nbd.2017.07.021  0.6
2017 Kajstura TJ, Dougherty SE, Linden DJ. Serotonin axons in the neocortex of the adult female mouse regrow after traumatic brain injury. Journal of Neuroscience Research. PMID 28485037 DOI: 10.1002/jnr.24059  0.92
2017 Shevelkin AV, Terrillion CE, Abazyan BN, Kajstura TJ, Jouroukhin YA, Rudow GL, Troncoso JC, Linden DJ, Pletnikov MV. Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice. Neurobiology of Disease. PMID 28392471 DOI: 10.1016/j.nbd.2017.04.008  0.6
2016 Cudmore RH, Dougherty SE, Linden DJ. Cerebral vascular structure in the motor cortex of adult mice is stable and is not altered by voluntary exercise. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X16682508. PMID 28059584 DOI: 10.1177/0271678X16682508  1
2016 Jin Y, Dougherty SE, Wood K, Sun L, Cudmore RH, Abdalla A, Kannan G, Pletnikov M, Hashemi P, Linden DJ. Regrowth of Serotonin Axons in the Adult Mouse Brain Following Injury. Neuron. PMID 27499084 DOI: 10.1016/j.neuron.2016.07.024  1
2015 Zhang Y, Cudmore RH, Lin DT, Linden DJ, Huganir RL. Visualization of NMDA receptor-dependent AMPA receptor synaptic plasticity in vivo. Nature Neuroscience. 18: 402-7. PMID 25643295 DOI: 10.1038/nn.3936  1
2013 Thomas GM, Hayashi T, Huganir RL, Linden DJ. DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15401-7. PMID 24068808 DOI: 10.1523/JNEUROSCI.1283-13.2013  1
2013 Das I, Park JM, Shin JH, Jeon SK, Lorenzi H, Linden DJ, Worley PF, Reeves RH. Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. Science Translational Medicine. 5: 201ra120. PMID 24005160 DOI: 10.1126/scitranslmed.3005983  1
2013 Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY, Linden DJ, Plomann M, Huganir RL. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. 110: 13976-81. PMID 23918399 DOI: 10.1073/pnas.1312467110  1
2013 Park JM, Hu JH, Milshteyn A, Zhang PW, Moore CG, Park S, Datko MC, Domingo RD, Reyes CM, Wang XJ, Etzkorn FA, Xiao B, Szumlinski KK, Kern D, Linden DJ, et al. A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. Cell. 154: 637-50. PMID 23911326 DOI: 10.1016/j.cell.2013.07.001  1
2013 Kim YS, Kang E, Makino Y, Park S, Shin JH, Song H, Launay P, Linden DJ. Characterizing the conductance underlying depolarization-induced slow current in cerebellar Purkinje cells. Journal of Neurophysiology. 109: 1174-81. PMID 23197456 DOI: 10.1152/jn.01168.2011  1
2012 He L, Linden DJ, Sapirstein A. Astrocyte inositol triphosphate receptor type 2 and cytosolic phospholipase A2 alpha regulate arteriole responses in mouse neocortical brain slices. Plos One. 7: e42194. PMID 22876307 DOI: 10.1371/journal.pone.0042194  1
2012 Linden DJ. A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis. Journal of Neurophysiology. 107: 448-54. PMID 22049330 DOI: 10.1152/jn.00824.2011  1
2012 Zhang W, Linden DJ. Calcium influx measured at single presynaptic boutons of cerebellar granule cell ascending axons and parallel fibers. Cerebellum (London, England). 11: 121-31. PMID 20049574 DOI: 10.1007/s12311-009-0151-3  1
2011 Bangash MA, Park JM, Melnikova T, Wang D, Jeon SK, Lee D, Syeda S, Kim J, Kouser M, Schwartz J, Cui Y, Zhao X, Speed HE, Kee SE, Tu JC, ... ... Linden DJ, et al. Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism. Cell. 145: 758-72. PMID 21565394 DOI: 10.1016/j.cell.2011.03.052  1
2011 Schonewille M, Gao Z, Boele HJ, Veloz MF, Amerika WE, Simek AA, De Jeu MT, Steinberg JP, Takamiya K, Hoebeek FE, Linden DJ, Huganir RL, De Zeeuw CI. Reevaluating the role of LTD in cerebellar motor learning. Neuron. 70: 43-50. PMID 21482355 DOI: 10.1016/j.neuron.2011.02.044  1
2010 Hu JH, Park JM, Park S, Xiao B, Dehoff MH, Kim S, Hayashi T, Schwarz MK, Huganir RL, Seeburg PH, Linden DJ, Worley PF. Homeostatic scaling requires group I mGluR activation mediated by Homer1a. Neuron. 68: 1128-42. PMID 21172614 DOI: 10.1016/j.neuron.2010.11.008  1
2010 Chang MC, Park JM, Pelkey KA, Grabenstatter HL, Xu D, Linden DJ, Sutula TP, McBain CJ, Worley PF. Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons. Nature Neuroscience. 13: 1090-7. PMID 20729843 DOI: 10.1038/nn.2621  1
2010 Smith-Hicks C, Xiao B, Deng R, Ji Y, Zhao X, Shepherd JD, Posern G, Kuhl D, Huganir RL, Ginty DD, Worley PF, Linden DJ. SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells. Nature Neuroscience. 13: 1082-9. PMID 20694003 DOI: 10.1038/nn.2611  1
2010 Linden DJ. Journal of Neurophysiology and the Neuroscience Peer Review Consortium (NPRC) Journal of Neurophysiology. 103: 1707. DOI: 10.1152/jn.00168.2010  1
2009 Zhang W, Linden DJ. Neuromodulation at single presynaptic boutons of cerebellar parallel fibers is determined by bouton size and basal action potential-evoked Ca transient amplitude. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15586-94. PMID 20007482 DOI: 10.1523/JNEUROSCI.3793-09.2009  1
2009 Kim YS, Shin JH, Hall FS, Linden DJ. Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8530-8. PMID 19571144 DOI: 10.1523/JNEUROSCI.0468-09.2009  1
2009 Shin JH, Kim YS, Worley PF, Linden DJ. Depolarization-induced slow current in cerebellar Purkinje cells does not require metabotropic glutamate receptor 1. Neuroscience. 162: 688-93. PMID 19409231 DOI: 10.1016/j.neuroscience.2009.01.044  1
2009 Linden DJ. Preprint servers and the Journal Of Neurophysiology Journal of Neurophysiology. 102: 2577. DOI: 10.1152/jn.00895.2009  1
2009 Lane JA, Linden DJ. Is there gender bias in the peer review process at Journal of Neurophysiology? Journal of Neurophysiology. 101: 2195-2196. DOI: 10.1152/jn.00196.2009  1
2008 Linden DJ. Warm, fuzzy feeling. Journal of Neurophysiology. 100: 1. PMID 18628365 DOI: 10.1152/jn.00000.2008  1
2008 Park S, Park JM, Kim S, Kim JA, Shepherd JD, Smith-Hicks CL, Chowdhury S, Kaufmann W, Kuhl D, Ryazanov AG, Huganir RL, Linden DJ, Worley PF. Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron. 59: 70-83. PMID 18614030 DOI: 10.1016/j.neuron.2008.05.023  1
2008 Takamiya K, Mao L, Huganir RL, Linden DJ. The glutamate receptor-interacting protein family of GluR2-binding proteins is required for long-term synaptic depression expression in cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5752-5. PMID 18509036 DOI: 10.1523/JNEUROSCI.0654-08.2008  1
2008 Kim SJ, Jin Y, Kim J, Shin JH, Worley PF, Linden DJ. Transient upregulation of postsynaptic IP3-gated Ca release underlies short-term potentiation of metabotropic glutamate receptor 1 signaling in cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4350-5. PMID 18434513 DOI: 10.1523/JNEUROSCI.0284-08.2008  1
2008 Cho RW, Park JM, Wolff SB, Xu D, Hopf C, Kim JA, Reddy RC, Petralia RS, Perin MS, Linden DJ, Worley PF. mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE. Neuron. 57: 858-71. PMID 18367087 DOI: 10.1016/j.neuron.2008.01.010  1
2008 Shin JH, Kim YS, Linden DJ. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 746-50. PMID 18174329 DOI: 10.1073/pnas.0709407105  1
2008 Linden DJ. Introducing neuro forum, a section for young neurophysiologists Journal of Neurophysiology. 100: 1159. DOI: 10.1152/jn.z9k-9086.2008  1
2008 Linden DJ. From molecules to memory in the cerebellum (Science (2003) (1682)) Science. 319: 1484.  1
2007 Kim SJ, Linden DJ. Ubiquitous plasticity and memory storage. Neuron. 56: 582-92. PMID 18031678 DOI: 10.1016/j.neuron.2007.10.030  1
2007 Nishiyama H, Fukaya M, Watanabe M, Linden DJ. Axonal motility and its modulation by activity are branch-type specific in the intact adult cerebellum. Neuron. 56: 472-87. PMID 17988631 DOI: 10.1016/j.neuron.2007.09.010  1
2007 Jin Y, Kim SJ, Kim J, Worley PF, Linden DJ. Long-term depression of mGluR1 signaling. Neuron. 55: 277-87. PMID 17640528 DOI: 10.1016/j.neuron.2007.06.035  1
2007 Nishiyama H, Linden DJ. Pure spillover transmission between neurons. Nature Neuroscience. 10: 675-7. PMID 17525760 DOI: 10.1038/nn0607-675  1
2007 Sdrulla AD, Linden DJ. Double dissociation between long-term depression and dendritic spine morphology in cerebellar Purkinje cells. Nature Neuroscience. 10: 546-8. PMID 17435753 DOI: 10.1038/nn1889  1
2007 Shen Y, Kishimoto K, Linden DJ, Sapirstein A. Cytosolic phospholipase A(2) alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatment. Proceedings of the National Academy of Sciences of the United States of America. 104: 6078-83. PMID 17389392 DOI: 10.1073/pnas.0605427104  1
2006 Sdrulla AD, Linden DJ. Dynamic imaging of cerebellar Purkinje cells reveals a population of filopodia which cross-link dendrites during early postnatal development. Cerebellum (London, England). 5: 105-15. PMID 16818385 DOI: 10.1080/14734220600620908  1
2006 Wagner KD, Kowatch RA, Emslie GJ, Findling RL, Wilens TE, McCague K, D'Souza J, Wamil A, Lehman RB, Berv D, Linden D. A double-blind, randomized, placebo-controlled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents. The American Journal of Psychiatry. 163: 1179-86. PMID 16816222 DOI: 10.1176/ajp.2006.163.7.1179  1
2006 Zhang W, Linden DJ. Long-term depression at the mossy fiber-deep cerebellar nucleus synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6935-44. PMID 16807323 DOI: 10.1523/JNEUROSCI.0784-06.2006  1
2006 Steinberg JP, Takamiya K, Shen Y, Xia J, Rubio ME, Yu S, Jin W, Thomas GM, Linden DJ, Huganir RL. Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. Neuron. 49: 845-60. PMID 16543133 DOI: 10.1016/j.neuron.2006.02.025  1
2006 Wagner KD, Kowatch RA, Emslie GJ, Findling RL, Wilens TE, McCague K, D'Souza J, Wamil A, Lehman RB, Berv D, Linden D. Dr. Wagner and colleagues reply [8] American Journal of Psychiatry. 163: 2196.  1
2005 Shin JH, Linden DJ. An NMDA receptor/nitric oxide cascade is involved in cerebellar LTD but is not localized to the parallel fiber terminal. Journal of Neurophysiology. 94: 4281-9. PMID 16120658 DOI: 10.1152/jn.00661.2005  1
2005 Shen Y, Linden DJ. Long-term potentiation of neuronal glutamate transporters. Neuron. 46: 715-22. PMID 15924858 DOI: 10.1016/j.neuron.2005.04.033  1
2005 Ramanan N, Shen Y, Sarsfield S, Lemberger T, Schütz G, Linden DJ, Ginty DD. SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability. Nature Neuroscience. 8: 759-67. PMID 15880109 DOI: 10.1038/nn1462  1
2004 Steinberg JP, Huganir RL, Linden DJ. N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. 101: 18212-6. PMID 15608060 DOI: 10.1073/pnas.0408278102  1
2004 Simsek-Duran F, Linden DJ, Lonart G. Adapter protein 14-3-3 is required for a presynaptic form of LTP in the cerebellum. Nature Neuroscience. 7: 1296-8. PMID 15543142 DOI: 10.1038/nn1348  1
2004 Leitges M, Kovac J, Plomann M, Linden DJ. A unique PDZ ligand in PKCalpha confers induction of cerebellar long-term synaptic depression. Neuron. 44: 585-94. PMID 15541307 DOI: 10.1016/j.neuron.2004.10.024  1
2004 Zhang W, Shin JH, Linden DJ. Persistent changes in the intrinsic excitability of rat deep cerebellar nuclear neurones induced by EPSP or IPSP bursts. The Journal of Physiology. 561: 703-19. PMID 15498810 DOI: 10.1113/jphysiol.2004.071696  1
2004 Nishiyama H, Linden DJ. Differential maturation of climbing fiber innervation in cerebellar vermis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3926-32. PMID 15102908 DOI: 10.1523/JNEUROSCI.5610-03.2004  1
2003 Kim SJ, Kim YS, Yuan JP, Petralia RS, Worley PF, Linden DJ. Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature. 426: 285-91. PMID 14614461 DOI: 10.1038/nature02162  1
2003 Zhang W, Linden DJ. The other side of the engram: experience-driven changes in neuronal intrinsic excitability. Nature Reviews. Neuroscience. 4: 885-900. PMID 14595400 DOI: 10.1038/nrn1248  1
2003 Linden DJ. Neuroscience. From molecules to memory in the cerebellum. Science (New York, N.Y.). 301: 1682-5. PMID 14500971 DOI: 10.1126/science.1090462  1
2003 Chung HJ, Steinberg JP, Huganir RL, Linden DJ. Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science (New York, N.Y.). 300: 1751-5. PMID 12805550 DOI: 10.1126/science.1082915  1
2003 Aizenman CD, Huang EJ, Linden DJ. Morphological correlates of intrinsic electrical excitability in neurons of the deep cerebellar nuclei. Journal of Neurophysiology. 89: 1738-47. PMID 12686564 DOI: 10.1152/jn.01043.2002  1
2003 Coesmans M, Smitt PA, Linden DJ, Shigemoto R, Hirano T, Yamakawa Y, van Alphen AM, Luo C, van der Geest JN, Kros JM, Gaillard CA, Frens MA, de Zeeuw CI. Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies. Annals of Neurology. 53: 325-36. PMID 12601700 DOI: 10.1002/ana.10451  1
2003 Weber JT, De Zeeuw CI, Linden DJ, Hansel C. Long-term depression of climbing fiber-evoked calcium transients in Purkinje cell dendrites. Proceedings of the National Academy of Sciences of the United States of America. 100: 2878-83. PMID 12601151 DOI: 10.1073/pnas.0536420100  1
2003 Lonart G, Schoch S, Kaeser PS, Larkin CJ, Südhof TC, Linden DJ. Phosphorylation of RIM1α by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses Cell. 115: 49-60. DOI: 10.1016/S0092-8674(03)00727-X  1
2002 Eto M, Bock R, Brautigan DL, Linden DJ. Cerebellar long-term synaptic depression requires PKC-mediated activation of CPI-17, a myosin/moesin phosphatase inhibitor. Neuron. 36: 1145-58. PMID 12495628 DOI: 10.1016/S0896-6273(02)01107-8  1
2002 Shen Y, Hansel C, Linden DJ. Glutamate release during LTD at cerebellar climbing fiber-Purkinje cell synapses. Nature Neuroscience. 5: 725-6. PMID 12134155 DOI: 10.1038/nn895  1
2001 Linden DJ. The expression of cerebellar LTD in culture is not associated with changes in AMPA-receptor kinetics, agonist affinity, or unitary conductance. Proceedings of the National Academy of Sciences of the United States of America. 98: 14066-71. PMID 11707583 DOI: 10.1073/pnas.241384598  1
2001 Hansel C, Linden DJ, D'Angelo E. Beyond parallel fiber LTD: the diversity of synaptic and non-synaptic plasticity in the cerebellum. Nature Neuroscience. 4: 467-75. PMID 11319554 DOI: 10.1038/87419  1
2000 Xia J, Chung HJ, Wihler C, Huganir RL, Linden DJ. Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron. 28: 499-510. PMID 11144359  1
2000 Ho N, Liauw JA, Blaeser F, Wei F, Hanissian S, Muglia LM, Wozniak DF, Nardi A, Arvin KL, Holtzman DM, Linden DJ, Zhuo M, Muglia LJ, Chatila TA. Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6459-72. PMID 10964952  1
2000 Aizenman CD, Huang EJ, Manis PB, Linden DJ. Use-dependent changes in synaptic strength at the Purkinje cell to deep nuclear synapse. Progress in Brain Research. 124: 257-73. PMID 10943131  1
2000 Hansel C, Linden DJ. Long-term depression of the cerebellar climbing fiber--Purkinje neuron synapse. Neuron. 26: 473-82. PMID 10839365  1
2000 Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 4926-31. PMID 10781100 DOI: 10.1073/pnas.97.9.4926  1
2000 Wang YT, Linden DJ. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron. 25: 635-47. PMID 10774731  1
2000 Takahashi KA, Linden DJ. Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells. Journal of Neurophysiology. 83: 1167-80. PMID 10712447  1
2000 Aizenman CD, Linden DJ. Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons. Nature Neuroscience. 3: 109-11. PMID 10649564 DOI: 10.1038/72049  1
1999 Linden DJ, Ahn S. Activation of presynaptic cAMP-dependent protein kinase is required for induction of cerebellar long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10221-7. PMID 10575019  1
1999 Aizenman CD, Linden DJ. Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum. Journal of Neurophysiology. 82: 1697-709. PMID 10515960  1
1999 Ahn S, Ginty DD, Linden DJ. A late phase of cerebellar long-term depression requires activation of CaMKIV and CREB. Neuron. 23: 559-68. PMID 10433267 DOI: 10.1016/S0896-6273(00)80808-9  1
1999 Linden DJ. The return of the spike: postsynaptic action potentials and the induction of LTP and LTD. Neuron. 22: 661-6. PMID 10230787 DOI: 10.1016/S0896-6273(00)80726-6  1
1999 Parent A, Linden DJ, Sisodia SS, Borchelt DR. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiology of Disease. 6: 56-62. PMID 10078973 DOI: 10.1006/nbdi.1998.0207  1
1998 Narasimhan K, Pessah IN, Linden DJ. Inositol-1,4,5-trisphosphate receptor-mediated Ca mobilization is not required for cerebellar long-term depression in reduced preparations. Journal of Neurophysiology. 80: 2963-74. PMID 9862899  1
1998 Aizenman CD, Manis PB, Linden DJ. Polarity of long-term synaptic gain change is related to postsynaptic spike firing at a cerebellar inhibitory synapse. Neuron. 21: 827-35. PMID 9808468 DOI: 10.1016/S0896-6273(00)80598-X  1
1998 Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron. 21: 717-26. PMID 9808459 DOI: 10.1016/S0896-6273(00)80589-9  1
1998 Storm DR, Hansel C, Hacker B, Parent A, Linden DJ. Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice. Neuron. 20: 1199-210. PMID 9655507 DOI: 10.1016/S0896-6273(00)80500-0  1
1998 Parent A, Schrader K, Munger SD, Reed RR, Linden DJ, Ronnett GV. Synaptic transmission and hippocampal long-term potentiation in olfactory cyclic nucleotide-gated channel type 1 null mouse. Journal of Neurophysiology. 79: 3295-301. PMID 9636130  1
1998 Linden DJ. Synaptically evoked glutamate transport currents may be used to detect the expression of long-term potentiation in cerebellar culture. Journal of Neurophysiology. 79: 3151-6. PMID 9636115  1
1998 De Zeeuw CI, Hansel C, Bian F, Koekkoek SK, van Alphen AM, Linden DJ, Oberdick J. Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron. 20: 495-508. PMID 9539124 DOI: 10.1016/S0896-6273(00)80990-3  1
1997 Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388: 769-73. PMID 9285588 DOI: 10.1038/42009  1
1997 Linden DJ. Long-term potentiation of glial synaptic currents in cerebellar culture. Neuron. 18: 983-94. PMID 9208865 DOI: 10.1016/S0896-6273(00)80337-2  1
1996 Jeromin A, Huganir RL, Linden DJ. Suppression of the glutamate receptor delta 2 subunit produces a specific impairment in cerebellar long-term depression. Journal of Neurophysiology. 76: 3578-83. PMID 8930298  1
1996 Linden DJ. A protein synthesis-dependent late phase of cerebellar long-term depression. Neuron. 17: 483-90. PMID 8816711 DOI: 10.1016/S0896-6273(00)80180-4  1
1996 Narasimhan K, Linden DJ. Defining a minimal computational unit for cerebellar long-term depression. Neuron. 17: 333-41. PMID 8780656 DOI: 10.1016/S0896-6273(00)80164-6  1
1996 Kaplin AI, Snyder SH, Linden DJ. Reduced nicotinamide adenine dinucleotide-selective stimulation of inositol 1,4,5-trisphosphate receptors mediates hypoxic mobilization of calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2002-11. PMID 8604044  1
1996 Linden DJ. Cerebellar long-term depression as investigated in a cell culture preparation Behavioral and Brain Sciences. 19: 339-346.  1
1995 Linden DJ. Phospholipase A2 controls the induction of short-term versus long-term depression in the cerebellar Purkinje neuron in culture. Neuron. 15: 1393-401. PMID 8845162 DOI: 10.1016/0896-6273(95)90017-9  1
1995 Linden DJ, Dawson TM, Dawson VL. An evaluation of the nitric oxide/cGMP/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5098-105. PMID 7623138  1
1995 Linden DJ, Connor JA. Long-term synaptic depression. Annual Review of Neuroscience. 18: 319-57. PMID 7605065 DOI: 10.1146/annurev.ne.18.030195.001535  1
1994 Linden DJ. Input-specific induction of cerebellar long-term depression does not require presynaptic alteration. Learning & Memory (Cold Spring Harbor, N.Y.). 1: 121-8. PMID 10467590  1
1994 Linden DJ. Long-term synaptic depression in the mammalian brain. Neuron. 12: 457-72. PMID 8155315 DOI: 10.1016/0896-6273(94)90205-4  1
1994 Linden DJ, Smeyne M, Connor JA. Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. Journal of Neurophysiology. 71: 1992-8. PMID 8064363  1
1993 Linden DJ, Connor JA. Cellular mechanisms of long-term depression in the cerebellum. Current Opinion in Neurobiology. 3: 401-6. PMID 8369630 DOI: 10.1016/0959-4388(93)90133-J  1
1993 Linden DJ, Narasimhan K, Gurfel D. Protoporphyrins modulate voltage-gated Ca current in AtT-20 pituitary cells. Journal of Neurophysiology. 70: 2673-7. PMID 7907135  1
1993 Linden DJ, Smeyne M, Connor JA. Induction of cerebellar long-term depression in culture requires postsynaptic action of sodium ions. Neuron. 11: 1093-100. PMID 7506045 DOI: 10.1016/0896-6273(93)90222-D  1
1992 Linden DJ, Connor JA. Long-term Depression of Glutamate Currents in Cultured Cerebellar Purkinje Neurons Does Not Require Nitric Oxide Signalling. The European Journal of Neuroscience. 4: 10-15. PMID 12106437  1
1992 Linden DJ, Smeyne M, Sun SC, Connor JA. An electrophysiological correlate of protein kinase C isozyme distribution in cultured cerebellar neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3601-8. PMID 1527599  1
1991 Linden DJ, Connor JA. Participation of postsynaptic PKC in cerebellar long-term depression in culture. Science (New York, N.Y.). 254: 1656-9. PMID 1721243  1
1991 Linden DJ, Dickinson MH, Smeyne M, Connor JA. A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons. Neuron. 7: 81-9. PMID 1676895 DOI: 10.1016/0896-6273(91)90076-C  1
1989 Nelson RB, Linden DJ, Hyman C, Pfenninger KH, Routtenberg A. The two major phosphoproteins in growth cones are probably identical to two protein kinase C substrates correlated with persistence of long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 381-9. PMID 2918368  1
1989 Nelson RB, Linden DJ, Routtenberg A. Phosphoproteins localized to presynaptic terminal linked to persistence of long-term potentiation (LTP): quantitative analysis of two-dimensional gels. Brain Research. 497: 30-42. PMID 2790456 DOI: 10.1016/0006-8993(89)90966-9  1
1989 Linden DJ, Routtenberg A. The role of protein kinase C in long-term potentiation: a testable model. Brain Research. Brain Research Reviews. 14: 279-96. PMID 2679942 DOI: 10.1016/0165-0173(89)90004-0  1
1989 Linden DJ, Routtenberg A. cis-Fatty acids, which activate protein kinase C, attenuate Na+ and Ca2+ currents in mouse neuroblastoma cells. The Journal of Physiology. 419: 95-119. PMID 2559978  1
1988 Barnes CA, Mizumori SJ, Lovinger DM, Sheu FS, Murakami K, Chan SY, Linden DJ, Nelson RB, Routtenberg A. Selective decline in protein F1 phosphorylation in hippocampus of senescent rats. Neurobiology of Aging. 9: 393-8. PMID 3185858 DOI: 10.1016/S0197-4580(88)80086-1  1
1988 Linden DJ, Wong KL, Sheu FS, Routtenberg A. NMDA receptor blockade prevents the increase in protein kinase C substrate (protein F1) phosphorylation produced by long-term potentiation. Brain Research. 458: 142-6. PMID 2905192 DOI: 10.1016/0006-8993(88)90506-9  1
1987 Linden DJ, Sheu FS, Murakami K, Routtenberg A. Enhancement of long-term potentiation by cis-unsaturated fatty acid: relation to protein kinase C and phospholipase A2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3783-92. PMID 2824717  1
1986 Linden DJ, Murakami K, Routtenberg A. A newly discovered protein kinase C activator (oleic acid) enhances long-term potentiation in the intact hippocampus. Brain Research. 379: 358-63. PMID 3091192 DOI: 10.1016/0006-8993(86)90790-0  1
1986 Akers RF, Lovinger DM, Colley PA, Linden DJ, Routtenberg A. Translocation of protein kinase C activity may mediate hippocampal long-term potentiation. Science (New York, N.Y.). 231: 587-9. PMID 3003904  1
1975 Hagamen WD, Linden DJ, Mai KF, Newell SM, Weber JC. PROGRAM GENERATOR Ibm Systems Journal. 14: 102-133.  0.32
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