Angele Parent - Publications

Affiliations: 
University of Chicago, Chicago, IL 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Deyts C, Clutter M, Pierce N, Chakrabarty P, Ladd TB, Goddi A, Rosario AM, Cruz P, Vetrivel K, Wagner SL, Thinakaran G, Golde TE, Parent AT. APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model. Cell Reports. 27: 1345-1355.e6. PMID 31042463 DOI: 10.1016/j.celrep.2019.03.087  0.72
2017 Andrew RJ, Fernandez CG, Stanley M, Jiang H, Nguyen P, Rice RC, Buggia-Prévot V, De Rossi P, Vetrivel KS, Lamb R, Argemi A, Allaert ES, Rathbun EM, Krause SV, Wagner SL, ... Parent AT, et al. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078331 DOI: 10.1073/pnas.1708568114  0.72
2016 De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, et al. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts. Molecular Neurodegeneration. 11: 59. PMID 27488240 DOI: 10.1186/s13024-016-0124-1  1
2016 Deyts C, Clutter M, Herrera S, Jovanovic N, Goddi A, Parent AT. Loss of presenilin function is associated with a selective gain of APP function. Elife. 5. PMID 27196744 DOI: 10.7554/eLife.15645  0.72
2016 Deyts C, Thinakaran G, Parent AT. APP Receptor? To Be or Not To Be. Trends in Pharmacological Sciences. PMID 26837733 DOI: 10.1016/j.tips.2016.01.005  0.72
2013 Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, et al. A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. Cell Reports. 5: 1552-63. PMID 24373286 DOI: 10.1016/j.celrep.2013.12.006  1
2012 Deyts C, Vetrivel KS, Das S, Shepherd YM, Dupré DJ, Thinakaran G, Parent AT. Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1714-29. PMID 22302812 DOI: 10.1523/JNEUROSCI.5433-11.2012  1
2011 Gong P, Roseman J, Fernandez CG, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT, Thinakaran G. Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice. Molecular Neurodegeneration. 6: 87. PMID 22204304 DOI: 10.1186/1750-1326-6-87  1
2010 Meckler X, Roseman J, Das P, Cheng H, Pei S, Keat M, Kassarjian B, Golde TE, Parent AT, Thinakaran G. Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16160-9. PMID 21123562 DOI: 10.1523/JNEUROSCI.4436-10.2010  1
2010 Gong P, Vetrivel KS, Nguyen PD, Meckler X, Cheng H, Kounnas MZ, Wagner SL, Parent AT, Thinakaran G. Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates. The Journal of Biological Chemistry. 285: 38042-52. PMID 20921220 DOI: 10.1074/jbc.M110.132613  1
2010 Parent AT, Thinakaran G. Modeling presenilin-dependent familial Alzheimer's disease: emphasis on presenilin substrate-mediated signaling and synaptic function. International Journal of Alzheimer's Disease. 2010. PMID 20798900 DOI: 10.4061/2010/825918  1
2008 Vetrivel KS, Kodam A, Gong P, Chen Y, Parent AT, Kar S, Thinakaran G. Localization and regional distribution of p23/TMP21 in the brain. Neurobiology of Disease. 32: 37-49. PMID 18652896 DOI: 10.1016/j.nbd.2008.06.012  1
2008 Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, et al. Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta. The Journal of Biological Chemistry. 283: 19489-98. PMID 18456655 DOI: 10.1074/jbc.M801037200  1
2008 Barnes NY, Shi J, Yajima H, Thinakaran G, Parent AT. Steady-state increase of cAMP-response element binding protein, Rac, and PAK signaling in presenilin-deficient neurons. Journal of Neurochemistry. 104: 1637-48. PMID 17996025 DOI: 10.1111/j.1471-4159.2007.05102.x  1
2007 Cheng H, Vetrivel KS, Gong P, Meckler X, Parent A, Thinakaran G. Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts. Nature Clinical Practice. Neurology. 3: 374-82. PMID 17611486 DOI: 10.1038/ncpneuro0549  1
2005 Vetrivel KS, Cheng H, Kim SH, Chen Y, Barnes NY, Parent AT, Sisodia SS, Thinakaran G. Spatial segregation of gamma-secretase and substrates in distinct membrane domains. The Journal of Biological Chemistry. 280: 25892-900. PMID 15886206 DOI: 10.1074/jbc.M503570200  1
2005 Parent AT, Barnes NY, Taniguchi Y, Thinakaran G, Sisodia SS. Presenilin attenuates receptor-mediated signaling and synaptic function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1540-9. PMID 15703408 DOI: 10.1523/JNEUROSCI.3850-04.2005  1
2004 Thinakaran G, Parent AT. Identification of the role of presenilins beyond Alzheimer's disease. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 50: 411-8. PMID 15304238 DOI: 10.1016/j.phrs.2003.12.026  1
2001 Valastro B, Girard M, Gagné J, Martin F, Parent AT, Baudry M, Massicotte G. Inositol hexakisphosphate-mediated regulation of glutamate receptors in rat brain sections. Hippocampus. 11: 673-82. PMID 11811661 DOI: 10.1002/hipo.1082  1
2001 Weaver IC, La Plante P, Weaver S, Parent A, Sharma S, Diorio J, Chapman KE, Seckl JR, Szyf M, Meaney MJ. Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites. Molecular and Cellular Endocrinology. 185: 205-18. PMID 11738810 DOI: 10.1016/S0303-7207(01)00635-9  0.4
2000 Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 4926-31. PMID 10781100 DOI: 10.1073/pnas.97.9.4926  1
2000 Zaman SH, Parent A, Laskey A, Lee MK, Borchelt DR, Sisodia SS, Malinow R. Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine. Neurobiology of Disease. 7: 54-63. PMID 10671322 DOI: 10.1006/nbdi.1999.0271  1
1999 Parent A, Linden DJ, Sisodia SS, Borchelt DR. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiology of Disease. 6: 56-62. PMID 10078973 DOI: 10.1006/nbdi.1998.0207  1
1998 Storm DR, Hansel C, Hacker B, Parent A, Linden DJ. Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice. Neuron. 20: 1199-210. PMID 9655507 DOI: 10.1016/S0896-6273(00)80500-0  1
1998 Parent A, Schrader K, Munger SD, Reed RR, Linden DJ, Ronnett GV. Synaptic transmission and hippocampal long-term potentiation in olfactory cyclic nucleotide-gated channel type 1 null mouse. Journal of Neurophysiology. 79: 3295-301. PMID 9636130  1
1995 Parent A, Rowe W, Meaney MJ, Quirion R. Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors. The Journal of Pharmacology and Experimental Therapeutics. 272: 1110-6. PMID 7891323  1
1995 Quirion R, Wilson A, Rowe W, Aubert I, Richard J, Doods H, Parent A, White N, Meaney MJ. Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1455-62. PMID 7869110  1
1995 Yashpal K, Pitcher GM, Parent A, Quirion R, Coderre TJ. Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3263-72. PMID 7751909  1
1995 Krieger C, Jacques D, Parent A, Quirion R. [3H]phorbol 12,13-dibutyrate/PKC binding in thoracic spinal cord: no change in amyotrophic lateral sclerosis. Neuroreport. 6: 1381-4. PMID 7488729  1
1994 Parent A, Quirion R. Differential localization and pH dependency of phosphoinositide 1,4,5-IP3, 1,3,4,5-IP4 and IP6 receptors in rat and human brains. The European Journal of Neuroscience. 6: 67-74. PMID 8130933 DOI: 10.1111/j.1460-9568.1994.tb00248.x  1
1994 Kar S, Quirion R, Parent A. An interaction between inositol hexakisphosphate (IP6) and insulin-like growth factor II receptor binding sites in the rat brain. Neuroreport. 5: 625-8. PMID 8025258  1
1994 Parent A, Poirier J, Baccichet A, Quirion R. Regulation of 1,4,5-IP3, 1,3,4,5-IP4 and IP6 binding sites following entorhinal cortex lesions in rat brain. Neuroscience. 61: 565-73. PMID 7969930 DOI: 10.1016/0306-4522(94)90434-0  1
1993 Parent A, Dea D, Quirion R, Poirier J. [3H]phorbol ester binding sites and neuronal plasticity in the hippocampus following entorhinal cortex lesions. Brain Research. 607: 23-32. PMID 8481798 DOI: 10.1016/0006-8993(93)91485-B  1
1992 Schiffrin EL, Parent A, St Louis J, Tremblay J, Garcia R, Thibault G. Vascular atrial natriuretic factor receptors in spontaneously hypertensive rats Cardiovascular Research. 26: 857-864. PMID 1360334  1
1992 Parent A, Nguyen PV, Yang XP, Schiffrin EL. Inositol phosphate production in response to [Arg8]vasopressin, endothelin 1, and prostaglandin F2 alpha in rat aorta and mesenteric arteries. Canadian Journal of Physiology and Pharmacology. 70: 1408-16. PMID 1337016  1
1992 Nguyen PV, Parent A, Deng LY, Flückiger JP, Thibault G, Schiffrin EL. Endothelin vascular receptors and responses in deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 19: II98-104. PMID 1310486  1
1991 Parent A, Schiffrin EL, St-Louis J. Receptors for Arg8-vasopressin, angiotensin II, and atrial natriuretic peptide in the mesenteric vasculature of pregnant rats Canadian Journal of Physiology and Pharmacology. 69: 137-144. PMID 1647264  1
1990 Parent A, Schiffrin EL, St-Louis J. Role of the endothelium in adrenergic responses of mesenteric artery rings of pregnant rats American Journal of Obstetrics and Gynecology. 163: 229-234. PMID 2375347  1
1989 Massicotte G, Parent A, St-Louis J. Blunted responses to vasoconstrictors in mesenteric vasculature but not in portal vein of spontaneously hypertensive rats treated with relaxin. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 190: 254-9. PMID 2922410  1
1989 Parent A, St-Louis J, Schiffrin EL. Vascular effects of bradykinin and sodium nitroprusside during pregnancy in the rat Hypertension in Pregnancy. 561-582. DOI: 10.3109/10641958909012929  1
1988 St-Louis J, Parent A, Gutkowska J, Genest J, Schiffrin EL. Vasorelaxation and vascular binding sites for atrial natriuretic peptide in pregnant rats American Journal of Physiology - Heart and Circulatory Physiology. 254: 23/6. PMID 2837912  1
1987 Massicotte G, St-Louis J, Parent A, Schiffrin EL. Decreased in vitro responses to vasoconstrictors during gestation in normotensive and spontaneously hypertensive rats. Canadian Journal of Physiology and Pharmacology. 65: 2466-71. PMID 3449203  1
1986 St-Louis J, Parent A, Lariviere R, Schiffrin EL. Vasopressin responses and receptors in the mesenteric vasculature of estrogen-treated rats American Journal of Physiology - Heart and Circulatory Physiology. 251: 20/5. PMID 3777197  1
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