| Year |
Citation |
Score |
| 2023 |
Alachkar N, Norton D, Wolkensdorfer Z, Muldoon M, Paszek P. Variability of the innate immune response is globally constrained by transcriptional bursting. Frontiers in Molecular Biosciences. 10: 1176107. PMID 37441161 DOI: 10.3389/fmolb.2023.1176107 |
0.412 |
|
| 2023 |
Downton P, Bagnall JS, England H, Spiller DG, Humphreys NE, Jackson DA, Paszek P, White MRH, Adamson AD. Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression. Frontiers in Molecular Biosciences. 10: 1187187. PMID 37228587 DOI: 10.3389/fmolb.2023.1187187 |
0.457 |
|
| 2022 |
Kalliara E, Kardynska M, Bagnall J, Spiller DG, Müller W, Ruckerl D, Śmieja J, Biswas SK, Paszek P. Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation. Frontiers in Immunology. 13: 947213. PMID 36238296 DOI: 10.3389/fimmu.2022.947213 |
0.333 |
|
| 2020 |
Bagnall J, Rowe W, Alachkar N, Roberts J, England H, Clark C, Platt M, Jackson DA, Muldoon M, Paszek P. Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling. Cell Systems. PMID 32918862 DOI: 10.1016/J.Cels.2020.08.007 |
0.498 |
|
| 2020 |
Paszek A, Kardyńska M, Bagnall J, Śmieja J, Spiller DG, Widłak P, Kimmel M, Widlak W, Paszek P. Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling. Cell Communication and Signaling : Ccs. 18: 77. PMID 32448393 DOI: 10.1186/S12964-020-00583-0 |
0.586 |
|
| 2019 |
Papoutsopoulou S, Burkitt MD, Bergey F, England H, Hough R, Schmidt L, Spiller DG, White MHR, Paszek P, Jackson DA, Martins Dos Santos VAP, Sellge G, Pritchard DM, Campbell BJ, Müller W, et al. Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients. Frontiers in Immunology. 10: 2168. PMID 31572379 DOI: 10.3389/Fimmu.2019.02168 |
0.425 |
|
| 2018 |
Bagnall J, Boddington C, England H, Brignall R, Downton P, Alsoufi Z, Boyd J, Rowe W, Bennett A, Walker C, Adamson A, Patel NMX, O'Cualain R, Schmidt L, Spiller DG, ... ... Paszek P, et al. Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation. Science Signaling. 11. PMID 30042130 DOI: 10.1126/Scisignal.Aaf3998 |
0.466 |
|
| 2018 |
Kardyńska M, Paszek A, Śmieja J, Spiller D, Widłak W, White MRH, Paszek P, Kimmel M. Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level. Plos Computational Biology. 14: e1006130. PMID 29708974 DOI: 10.1371/Journal.Pcbi.1006130 |
0.633 |
|
| 2017 |
Brignall R, Cauchy P, Bevington SL, Gorman B, Pisco AO, Bagnall J, Boddington C, Rowe W, England H, Rich K, Schmidt L, Dyer NP, Travis MA, Ott S, Jackson DA, ... ... Paszek P, et al. Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28904128 DOI: 10.4049/Jimmunol.1602033 |
0.428 |
|
| 2017 |
Sellge G, Papoutsopoulou S, Verdier J, Trautwein C, Bergey F, Burkitt M, Sheibani R, Pierik M, Jonkers D, White M, Paszek P, Santos VMd, Rosenstiel P, Müller W, Probert C. DOP049 Inflammatory dyskinesis: defects of NF-κB dynamic behaviour as a new potential biomarker for personalized medicine in inflammatory bowel disease. Journal of Crohns & Colitis. 11. DOI: 10.1093/Ecco-Jcc/Jjx002.086 |
0.332 |
|
| 2016 |
Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, White MR, Goodfellow M, Galla T, Rattray M, Papalopulu N. Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation. Elife. 5. PMID 27700985 DOI: 10.7554/Elife.16118 |
0.343 |
|
| 2016 |
Assas BM, Levison S, Little M, England H, Battrick L, Bagnall J, McLaughlin J, Paszek P, Else KJ, Pennock JL. Anti-inflammatory effects of infliximab in mice are independent of TNFα neutralization. Clinical and Experimental Immunology. PMID 27669117 DOI: 10.1111/Cei.12872 |
0.333 |
|
| 2016 |
Adamson A, Boddington C, Downton P, Rowe W, Bagnall J, Lam C, Maya-Mendoza A, Schmidt L, Harper CV, Spiller DG, Rand DA, Jackson DA, White MR, Paszek P. Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states. Nature Communications. 7: 12057. PMID 27381163 DOI: 10.1038/Ncomms12057 |
0.534 |
|
| 2016 |
Ankers JM, Awais R, Jones NA, Boyd J, Ryan S, Adamson AD, Harper CV, Bridge L, Spiller DG, Jackson DA, Paszek P, Sée V, White MR. Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation. Elife. 5. PMID 27185527 DOI: 10.7554/Elife.10473 |
0.54 |
|
| 2016 |
Ankers JM, Awais R, Jones NA, Boyd J, Ryan S, Adamson AD, Harper CV, Bridge L, Spiller DG, Jackson DA, Paszek P, Sée V, White MR. Author response: Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation Elife. DOI: 10.7554/Elife.10473.038 |
0.462 |
|
| 2015 |
Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P. Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 713-25. PMID 25990200 DOI: 10.1039/C5Ib00067J |
0.512 |
|
| 2015 |
West S, Bridge LJ, White MR, Paszek P, Biktashev VN. A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system. Journal of Mathematical Biology. 70: 591-620. PMID 24658784 DOI: 10.1007/S00285-014-0775-X |
0.352 |
|
| 2014 |
Paszek P. From measuring noise toward integrated single-cell biology. Frontiers in Genetics. 5: 408. PMID 25477903 DOI: 10.3389/Fgene.2014.00408 |
0.344 |
|
| 2012 |
Wang Y, Paszek P, Horton CA, Yue H, White MR, Kell DB, Muldoon MR, Broomhead DS. A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation. Journal of Theoretical Biology. 297: 137-47. PMID 22202812 DOI: 10.1016/J.Jtbi.2011.12.014 |
0.475 |
|
| 2011 |
Wang Y, Paszek P, Horton CA, Kell DB, White MR, Broomhead DS, Muldoon MR. Interactions among oscillatory pathways in NF-kappa B signaling. Bmc Systems Biology. 5: 23. PMID 21291535 DOI: 10.1186/1752-0509-5-23 |
0.365 |
|
| 2010 |
Paszek P, Jackson DA, White MR. Oscillatory control of signalling molecules. Current Opinion in Genetics & Development. 20: 670-6. PMID 20850963 DOI: 10.1016/J.Gde.2010.08.004 |
0.432 |
|
| 2010 |
Turner DA, Paszek P, Woodcock DJ, Nelson DE, Horton CA, Wang Y, Spiller DG, Rand DA, White MR, Harper CV. Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells. Journal of Cell Science. 123: 2834-43. PMID 20663918 DOI: 10.1242/Jcs.069641 |
0.546 |
|
| 2010 |
Paszek P, Ryan S, Ashall L, Sillitoe K, Harper CV, Spiller DG, Rand DA, White MR. Population robustness arising from cellular heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. 107: 11644-9. PMID 20534546 DOI: 10.1073/Pnas.0913798107 |
0.506 |
|
| 2010 |
Harper CV, Featherstone K, Semprini S, Friedrichsen S, McNeilly J, Paszek P, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR. Dynamic organisation of prolactin gene expression in living pituitary tissue. Journal of Cell Science. 123: 424-30. PMID 20130141 DOI: 10.1242/Jcs.060434 |
0.414 |
|
| 2009 |
Ashall L, Horton CA, Nelson DE, Paszek P, Harper CV, Sillitoe K, Ryan S, Spiller DG, Unitt JF, Broomhead DS, Kell DB, Rand DA, Sée V, White MR. Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription. Science (New York, N.Y.). 324: 242-6. PMID 19359585 DOI: 10.1126/Science.1164860 |
0.498 |
|
| 2007 |
Lipniacki T, Puszynski K, Paszek P, Brasier AR, Kimmel M. Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling. Bmc Bioinformatics. 8: 376. PMID 17925009 DOI: 10.1186/1471-2105-8-376 |
0.658 |
|
| 2007 |
Paszek P. Modeling stochasticity in gene regulation: characterization in the terms of the underlying distribution function. Bulletin of Mathematical Biology. 69: 1567-601. PMID 17361363 DOI: 10.1007/S11538-006-9176-7 |
0.404 |
|
| 2007 |
Hat B, Paszek P, Kimmel M, Piechor K, Lipniacki T. How the number of alleles influences gene expression Journal of Statistical Physics. 128: 511-533. DOI: 10.1007/S10955-006-9218-4 |
0.535 |
|
| 2006 |
Lipniacki T, Paszek P, Brasier AR, Luxon BA, Kimmel M. Stochastic regulation in early immune response. Biophysical Journal. 90: 725-42. PMID 16284261 DOI: 10.1529/Biophysj.104.056754 |
0.654 |
|
| 2006 |
Lipniacki T, Paszek P, Marciniak-Czochra A, Brasier AR, Kimmel M. Transcriptional stochasticity in gene expression. Journal of Theoretical Biology. 238: 348-67. PMID 16039671 DOI: 10.1016/J.Jtbi.2005.05.032 |
0.586 |
|
| 2005 |
Paszek P, Lipniacki T, Brasier AR, Tian B, Nowak DE, Kimmel M. Stochastic effects of multiple regulators on expression profiles in eukaryotes. Journal of Theoretical Biology. 233: 423-33. PMID 15652150 DOI: 10.1016/J.Jtbi.2004.10.023 |
0.63 |
|
| 2004 |
Lipniacki T, Paszek P, Brasier AR, Luxon B, Kimmel M. Mathematical model of NF-kappaB regulatory module. Journal of Theoretical Biology. 228: 195-215. PMID 15094015 DOI: 10.1016/J.Jtbi.2004.01.001 |
0.608 |
|
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