Pamela J. Lein - Publications

Affiliations: 
University of California, Davis, Davis, CA 
Area:
developmental neurobiology, dendrites

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Karunungan K, Garza RH, Grodzki AC, Holt M, Lein PJ, Chandrasekaran V. Gamma secretase activity modulates BMP-7-induced dendritic growth in primary rat sympathetic neurons. Autonomic Neuroscience : Basic & Clinical. 247: 103085. PMID 37031474 DOI: 10.1016/j.autneu.2023.103085  0.382
2022 Yaghoobi B, Miller GW, Holland EB, Li X, Harvey D, Li S, Lehmler HJ, Pessah IN, Lein PJ. Ryanodine receptor-active non-dioxin-like polychlorinated biphenyls cause neurobehavioral deficits in larval zebrafish. Frontiers in Toxicology. 4: 947795. PMID 36278027 DOI: 10.3389/ftox.2022.947795  0.55
2021 Sethi S, Keil Stietz KP, Valenzuela AE, Klocke CR, Silverman JL, Puschner B, Pessah IN, Lein PJ. Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium. Frontiers in Neuroscience. 15: 766826. PMID 34938155 DOI: 10.3389/fnins.2021.766826  0.495
2021 Keil Stietz KP, Sethi S, Klocke CR, de Ruyter TE, Wilson MD, Pessah IN, Lein PJ. Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polychlorinated Biphenyls Mixture in the Juvenile Mouse. Frontiers in Neuroscience. 15: 766802. PMID 34924936 DOI: 10.3389/fnins.2021.766802  0.569
2021 Ly C, Greb AC, Vargas MV, Duim WC, Grodzki ACG, Lein PJ, Olson DE. Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth. Acs Pharmacology & Translational Science. 4: 452-460. PMID 33860174 DOI: 10.1021/acsptsci.0c00065  0.349
2020 Panesar HK, Kennedy CL, Keil Stietz KP, Lein PJ. Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? Toxics. 8. PMID 32957475 DOI: 10.3390/Toxics8030070  0.3
2020 Supasai S, González EA, Rowland DJ, Hobson B, Bruun DA, Guignet MA, Soares S, Singh V, Wulff H, Saito N, Harvey DJ, Lein PJ. Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate. European Journal of Pharmacology. 173538. PMID 32898549 DOI: 10.1016/J.Ejphar.2020.173538  0.305
2020 Berg EL, Pedersen LR, Pride MC, Petkova SP, Patten KT, Valenzuela AE, Wallis C, Bein KJ, Wexler A, Lein PJ, Silverman JL. Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats. Translational Psychiatry. 10: 289. PMID 32807767 DOI: 10.1038/S41398-020-00978-0  0.315
2020 Jett DA, Sibrizzi CA, Blain RB, Hartman PA, Lein PJ, Taylor KW, Rooney AA. A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent. Critical Reviews in Toxicology. 1-17. PMID 32755358 DOI: 10.1080/10408444.2020.1787330  0.308
2020 Patten KT, González EA, Valenzuela A, Berg E, Wallis C, Garbow JR, Silverman JL, Bein KJ, Wexler AS, Lein PJ. Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats. Translational Psychiatry. 10: 166. PMID 32483143 DOI: 10.1038/S41398-020-0845-3  0.315
2020 Schmuck MR, Keil KP, Sethi S, Morgan RK, Lein PJ. Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat cortical neurons in culture. Journal of Neuroscience Methods. 108793. PMID 32461071 DOI: 10.1016/J.Jneumeth.2020.108793  0.43
2020 Goshi N, Morgan RK, Lein PJ, Seker E. A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. Journal of Neuroinflammation. 17: 155. PMID 32393376 DOI: 10.1186/S12974-020-01819-Z  0.371
2020 Klocke C, Lein PJ. Evidence Implicating Non-Dioxin-Like Congeners as the Key Mediators of Polychlorinated Biphenyl (PCB) Developmental Neurotoxicity. International Journal of Molecular Sciences. 21. PMID 32033061 DOI: 10.3390/Ijms21031013  0.339
2020 Dunlap LE, Azinfar A, Ly C, Cameron LP, Viswanathan J, Tombari RJ, Myers-Turnbull D, Taylor JC, Grodzki AC, Lein PJ, Kokel D, Olson DE. Identification of Psychoplastogenic ,-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies. Journal of Medicinal Chemistry. PMID 31977208 DOI: 10.1021/Acs.Jmedchem.9B01404  0.36
2020 Matelski L, Morgan RK, Grodzki AC, Van de Water J, Lein PJ. Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line. Molecular Psychiatry. PMID 31965031 DOI: 10.1038/S41380-020-0647-2  0.409
2019 Klocke C, Sethi S, Lein PJ. The developmental neurotoxicity of legacy vs. contemporary polychlorinated biphenyls (PCBs): similarities and differences. Environmental Science and Pollution Research International. PMID 31713823 DOI: 10.1007/S11356-019-06723-5  0.37
2019 Yang J, Bruun DA, Wang C, Wan D, Reynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicology and Applied Pharmacology. 114749. PMID 31521729 DOI: 10.1016/J.Taap.2019.114749  0.311
2019 Walter KM, Dach K, Hayakawa K, Giersiefer S, Heuer H, Lein PJ, Fritsche E. Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison. Plos One. 14: e0221230. PMID 31513589 DOI: 10.1371/Journal.Pone.0221230  0.328
2019 Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG. Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice. Environmental Pollution (Barking, Essex : 1987). 253: 708-721. PMID 31336350 DOI: 10.1016/J.Envpol.2019.07.066  0.529
2019 Hennebelle M, Morgan RK, Sethi S, Zhang Z, Chen H, Grodzki AC, Lein PJ, Taha AY. Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner. Journal of Neurochemistry. PMID 31283837 DOI: 10.1111/Jnc.14818  0.364
2019 Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ. Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish. Neurotoxicology. PMID 31121238 DOI: 10.1016/J.Neuro.2019.05.008  0.308
2019 Pravoverov K, Whiting K, Thapa S, Bushong T, Trang K, Lein PJ, Chandrasekaran V. MicroRNAs are Necessary for BMP-7-induced Dendritic Growth in Cultured Rat Sympathetic Neurons. Cellular and Molecular Neurobiology. PMID 31104181 DOI: 10.1007/S10571-019-00688-2  0.367
2019 Proskocil BJ, Grodzki ACG, Jacoby DB, Lein PJ, Fryer AD. Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 30978295 DOI: 10.1165/Rcmb.2018-0257Oc  0.468
2019 Pessah IN, Lein PJ, Seegal RF, Sagiv SK. Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta Neuropathologica. PMID 30976975 DOI: 10.1007/S00401-019-01978-1  0.501
2019 Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiology of Disease. PMID 30905768 DOI: 10.1016/J.Nbd.2019.03.019  0.318
2019 Sethi S, Morgan R, Feng W, Lin Y, Li X, Luna C, Koch M, Bansal R, Duffel MW, Puschner B, Zoeller TR, Lehmler HJ, Pessah IN, Lein PJ. Comparative analyses of the 12 most abundant PCB congeners detected in human maternal serum for activity at the thyroid hormone receptor and ryanodine receptor. Environmental Science & Technology. PMID 30821444 DOI: 10.1021/Acs.Est.9B00535  0.539
2019 Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. 34.1 GENETIC MUTATIONS AND ENVIRONMENTAL FACTORS THAT PROMOTE ADVERSE NEURODEVELOPMENTAL OUTCOMES IN PRECLINICAL MODELS Journal of the American Academy of Child & Adolescent Psychiatry. 58: S351. DOI: 10.1016/J.Jaac.2019.07.844  0.478
2018 Frank DF, Brander SM, Hasenbein S, Harvey DJ, Lein PJ, Geist J, Connon RE. Developmental exposure to environmentally relevant concentrations of bifenthrin alters transcription of mTOR and ryanodine receptor-dependent signaling molecules and impairs predator avoidance behavior across early life stages in inland silversides (Menidia beryllina). Aquatic Toxicology (Amsterdam, Netherlands). 206: 1-13. PMID 30414561 DOI: 10.1016/J.Aquatox.2018.10.014  0.332
2018 Keil KP, Sethi S, Lein PJ. Sex-dependent effects of 2,2',3,5',6-pentachlorobiphenyl (PCB 95) on dendritic arborization of primary mouse neurons. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30395321 DOI: 10.1093/Toxsci/Kfy277  0.459
2018 Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. Genetic mutations in Ca signaling alter dendrite morphology and social approach in juvenile mice. Genes, Brain, and Behavior. e12526. PMID 30311737 DOI: 10.1111/Gbb.12526  0.58
2018 Sethi S, Keil KP, Lein PJ. 3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism. Archives of Toxicology. PMID 30225637 DOI: 10.1007/S00204-018-2307-8  0.499
2018 Keil KP, Miller GW, Chen H, Sethi S, Schmuck MR, Dhakal K, Kim JW, Lein PJ. PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Archives of Toxicology. PMID 30132043 DOI: 10.1007/S00204-018-2285-X  0.501
2018 Shaffo FC, Grodzki AC, Fryer AD, Lein PJ. Mechanisms of Organophosphorus Pesticide Toxicity in the Context of Airway Hyperreactivity and Asthma. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29952220 DOI: 10.1152/Ajplung.00211.2018  0.463
2018 Shaffo FC, Grodzki AC, Schelegle ES, Lein PJ. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29939342 DOI: 10.1093/Toxsci/Kfy158  0.303
2018 Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ. Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). Aquatic Toxicology (Amsterdam, Netherlands). 200: 50-61. PMID 29727771 DOI: 10.1016/J.Aquatox.2018.04.003  0.381
2018 Miller GW, Chandrasekaran V, Yaghoobi B, Lein PJ. Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity. Neurotoxicology. PMID 29704525 DOI: 10.1016/J.Neuro.2018.04.016  0.416
2018 Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg H, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, et al. Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicology and Applied Pharmacology. PMID 29447839 DOI: 10.1016/J.Taap.2018.02.004  0.337
2018 Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ. Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex. Journal of Neuroinflammation. 15: 7. PMID 29306331 DOI: 10.1186/S12974-017-1050-Z  0.38
2017 Sethi S, Keil KP, Lein PJ. Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3'-Dichlorobiphenyl (PCB 11). Toxics. 6. PMID 29295518 DOI: 10.3390/Toxics6010004  0.458
2017 Frank DF, Miller GW, Connon RE, Geist J, Lein PJ. Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95. Peerj. 5: e4106. PMID 29201571 DOI: 10.7717/Peerj.4106  0.345
2017 Keil KP, Sethi S, Wilson MD, Chen H, Lein PJ. In vivo and in vitro sex differences in the dendritic morphology of developing murine hippocampal and cortical neurons. Scientific Reports. 7: 8486. PMID 28814778 DOI: 10.1038/S41598-017-08459-Z  0.424
2017 Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. Aquatic Toxicology (Amsterdam, Netherlands). 190: 1-10. PMID 28662416 DOI: 10.1016/J.Aquatox.2017.06.019  0.332
2017 Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ, Seker E. Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance. Advanced Functional Materials. 27. PMID 28626362 DOI: 10.1002/Adfm.201604631  0.32
2017 Sethi S, Keil KP, Chen H, Hayakawa K, Li X, Lin Y, Lehmler HJ, Puschner B, Lein PJ. Detection of 3,3'-Dichlorobiphenyl in Human Maternal Plasma and Its Effects on Axonal and Dendritic Growth in Primary Rat Neurons. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28510766 DOI: 10.1093/Toxsci/Kfx100  0.462
2017 Kania-Korwel I, Lukasiewicz T, Barnhart CD, Stamou M, Chung H, Kelly KM, Bandiera S, Lein PJ, Lehmler HJ. Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28431184 DOI: 10.1093/Toxsci/Kfx071  0.304
2017 Chen H, Judkins J, Thomas C, Wu M, Khoury L, Benjamin CG, Pacione D, Golfinos JG, Kumthekar P, Ghamsari F, Chen L, Lein P, Chetkovich DM, Snuderl M, Horbinski C. Mutant IDH1 and seizures in patients with glioma. Neurology. PMID 28404805 DOI: 10.1212/Wnl.0000000000003911  0.517
2017 Sisó S, Hobson BA, Harvey DJ, Bruun DA, Rowland DJ, Garbow JR, Lein PJ. Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication with Diisopropylfluorophosphate. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28329845 DOI: 10.1093/Toxsci/Kfx048  0.338
2017 Wilson MD, Sethi S, Lein PJ, Keil KP. Valid Statistical Approaches for Analyzing Sholl Data: Mixed Effects versus Simple Linear Models. Journal of Neuroscience Methods. PMID 28104486 DOI: 10.1016/J.Jneumeth.2017.01.003  0.3
2017 Proskocil B, Lein P, Jacoby D, Fryer A. Organophosphorus pesticides increase inflammatory cytokines by activating macrophage Mac-1 European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa4926  0.479
2017 Chen H, Judkins J, Ghamsari F, Lein P, Horbinski C. OS05.1 The D-2-hydroxyglutarate product of mutant IDH1 induces synchronized neuronal firing via NMDA receptor activation Neuro-Oncology. 19: iii8-iii9. DOI: 10.1093/Neuonc/Nox036.028  0.557
2016 Voorhees JR, Rohlman DS, Lein PJ, Pieper AA. Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds. Frontiers in Neuroscience. 10: 590. PMID 28149268 DOI: 10.3389/Fnins.2016.00590  0.348
2016 Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ. BDE-47 and BDE-49 Inhibit Axonal Growth in Primary Rat Hippocampal Neuron-Glia Co-Cultures via Ryanodine Receptor-Dependent Mechanisms. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28003438 DOI: 10.1093/Toxsci/Kfw259  0.497
2016 Chapman CA, Chen H, Stamou M, Lein PJ, Seker E. Mechanisms of Reduced Astrocyte Surface Coverage in Cortical Neuron-Glia Co-cultures on Nanoporous Gold Surfaces. Cellular and Molecular Bioengineering. 9: 433-442. PMID 27795742 DOI: 10.1007/S12195-016-0449-4  0.329
2016 Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Annals of the New York Academy of Sciences. PMID 27467073 DOI: 10.1111/Nyas.13137  0.514
2016 Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, Hogberg HT, Leist M, Li A, Mundi WR, Padilla S, Piersma AH, Bal-Price A, Seiler A, Westerink R, ... ... Lein P, et al. Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use. Altex. PMID 27452664 DOI: 10.14573/Altex.1604201  0.322
2016 Lee YS, Lewis JA, Ippolito DL, Hussainzada N, Lein PJ, Jackson DA, Stallings JD. Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides. Toxicology. PMID 26775027 DOI: 10.1016/J.Tox.2016.01.001  0.355
2016 Chen H, Judkins J, Ghamsari F, Lein P, Horbinski C. QLIF-03. MUTANT IDH1 PROMOTES TUMOR-ASSOCIATED EPILEPSY IN GLIOMA PATIENTS Neuro-Oncology. 18: vi156-vi156. DOI: 10.1093/Neuonc/Now212.649  0.463
2015 Courter LA, Shaffo FC, Ghogha A, Parrish DJ, Lorentz CU, Habecker BA, Lein PJ. BMP7-Induced Dendritic Growth in Sympathetic Neurons Requires p75(NTR) Signaling. Developmental Neurobiology. PMID 26663679 DOI: 10.1002/Dneu.22371  0.488
2015 Bui-Nguyen TM, Baer CE, Lewis JA, Yang D, Lein PJ, Jackson DA. Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio. Bmc Genomics. 16: 853. PMID 26499117 DOI: 10.1186/S12864-015-1941-2  0.314
2015 Chandrasekaran V, Lea C, Sosa JC, Higgins D, Lein PJ. Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neurons. Molecular and Cellular Neurosciences. 67: 116-125. PMID 26079955 DOI: 10.1016/J.Mcn.2015.06.007  0.608
2015 Proskocil BJ, Bruun DA, Garg JA, Villagomez CC, Jacoby DB, Lein PJ, Fryer AD. Sensitization Can Influence Mechanisms of Organophosphorus Pesticide-Induced Airway Hyperreactivity. American Journal of Respiratory Cell and Molecular Biology. PMID 25897622 DOI: 10.1165/Rcmb.2014-0444Oc  0.476
2015 Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 95: 332-42. PMID 25882826 DOI: 10.1016/J.Neuropharm.2015.03.035  0.551
2015 Li Y, Lein PJ, Ford GD, Liu C, Stovall KC, White TE, Bruun DA, Tewolde T, Gates AS, Distel TJ, Surles-Zeigler MC, Ford BD. Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury. Journal of Neuroinflammation. 12: 64. PMID 25880399 DOI: 10.1186/S12974-015-0283-Y  0.337
2015 Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ. Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. Molecular Brain. 8: 10. PMID 25757474 DOI: 10.1186/S13041-015-0099-9  0.404
2015 Chapman CA, Chen H, Stamou M, Biener J, Biener MM, Lein PJ, Seker E. Nanoporous gold as a neural interface coating: effects of topography, surface chemistry, and feature size. Acs Applied Materials & Interfaces. 7: 7093-100. PMID 25706691 DOI: 10.1021/Acsami.5B00410  0.307
2015 Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture. Molecular Pharmacology. 87: 595-605. PMID 25583085 DOI: 10.1124/Mol.114.096701  0.541
2015 Grodzki AC, Poola B, Pasupuleti N, Nantz MH, Lein PJ, Gorin F. A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1β expression. The Journal of Pharmacology and Experimental Therapeutics. 352: 438-47. PMID 25538105 DOI: 10.1124/Jpet.114.220186  0.318
2015 Lein P. The developmental neurotoxicity of non-dioxin-like PCBs: Sensitization of ryanodine receptors interferes with neurodevelopmental processes that determine neuronal connectivity Neurotoxicology and Teratology. 49: 118. DOI: 10.1016/J.Ntt.2015.04.063  0.392
2014 Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicology and Applied Pharmacology. 281: 185-94. PMID 25448683 DOI: 10.1016/J.Taap.2014.10.001  0.314
2014 Moore CE, Lein PJ, Puschner B. Microcystins alter chemotactic behavior in Caenorhabditis elegans by selectively targeting the AWA sensory neuron. Toxins. 6: 1813-36. PMID 24918360 DOI: 10.3390/Toxins6061813  0.425
2014 Lesiak A, Zhu M, Chen H, Appleyard SM, Impey S, Lein PJ, Wayman GA. The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 717-25. PMID 24431430 DOI: 10.1523/Jneurosci.2884-13.2014  0.312
2014 Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicological Sciences : An Official Journal of the Society of Toxicology. 138: 379-92. PMID 24385416 DOI: 10.1093/Toxsci/Kft334  0.66
2013 Wu X, Kania-Korwel I, Chen H, Stamou M, Dammanahalli KJ, Duffel M, Lein PJ, Lehmler HJ. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 933-47. PMID 23581876 DOI: 10.3109/00498254.2013.785626  0.307
2013 Proskocil BJ, Bruun DA, Jacoby DB, van Rooijen N, Lein PJ, Fryer AD. Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L519-29. PMID 23377347 DOI: 10.1152/Ajplung.00381.2012  0.466
2013 Stamou M, Streifel KM, Goines PE, Lein PJ. Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders. Neurotoxicology and Teratology. 36: 3-16. PMID 23269408 DOI: 10.1016/J.Ntt.2012.12.001  0.389
2012 Ellison CA, Crane AL, Bonner MR, Knaak JB, Browne RW, Lein PJ, Olson JR. PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos. Toxicology and Applied Pharmacology. 265: 308-15. PMID 22975224 DOI: 10.1016/J.Taap.2012.08.031  0.307
2012 Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MH, Lein PJ, Veng-Pedersen P, Lehmler HJ. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice. Environmental Science & Technology. 46: 11393-401. PMID 22974126 DOI: 10.1021/Es302810T  0.312
2012 Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 362-72. PMID 22889812 DOI: 10.1093/Toxsci/Kfs244  0.552
2012 Li Y, Lein PJ, Liu C, Bruun DA, Giulivi C, Ford GD, Tewolde T, Ross-Inta C, Ford BD. Neuregulin-1 is neuroprotective in a rat model of organophosphate-induced delayed neuronal injury. Toxicology and Applied Pharmacology. 262: 194-204. PMID 22583949 DOI: 10.1016/J.Taap.2012.05.001  0.377
2012 Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environmental Health Perspectives. 120: 1003-9. PMID 22534176 DOI: 10.1289/Ehp.1104833  0.641
2012 Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environmental Health Perspectives. 120: 997-1002. PMID 22534141 DOI: 10.1289/Ehp.1104832  0.643
2012 Ghogha A, Bruun DA, Lein PJ. Inducing dendritic growth in cultured sympathetic neurons. Journal of Visualized Experiments : Jove. PMID 22473299 DOI: 10.3791/3546  0.499
2012 van Thriel C, Westerink RH, Beste C, Bale AS, Lein PJ, Leist M. Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts. Neurotoxicology. 33: 911-24. PMID 22008243 DOI: 10.1016/J.Neuro.2011.10.002  0.455
2012 Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Erratum: “ Para – and Ortho -SubstitutionsAre Key Determinants of Polybrominated Diphenyl Ether Activity toward RyanodineReceptors and Neurotoxicity” Environmental Health Perspectives. 120. DOI: 10.1289/ehp.120-a189  0.418
2011 Grodzki AC, Ghogha A, Mangini L, Fryer AD, Lein PJ. IFNγ Increases M2 Muscarinic Receptor Expression in Cultured Sympathetic Neurons. Current Neurobiology. 2: 23-29. PMID 23226931  0.434
2011 Lein PJ, Barnhart CD, Pessah IN. Acute hippocampal slice preparation and hippocampal slice cultures. Methods in Molecular Biology (Clifton, N.J.). 758: 115-34. PMID 21815062 DOI: 10.1007/978-1-61779-170-3_8  0.568
2011 Garred MM, Wang MM, Guo X, Harrington CA, Lein PJ. Transcriptional responses of cultured rat sympathetic neurons during BMP-7-induced dendritic growth. Plos One. 6: e21754. PMID 21765909 DOI: 10.1371/Journal.Pone.0021754  0.495
2011 Ellison CA, Smith JN, Lein PJ, Olson JR. Pharmacokinetics and pharmacodynamics of chlorpyrifos in adult male Long-Evans rats following repeated subcutaneous exposure to chlorpyrifos. Toxicology. 287: 137-44. PMID 21708215 DOI: 10.1016/J.Tox.2011.06.010  0.313
2011 Li Y, Lein PJ, Liu C, Bruun DA, Tewolde T, Ford G, Ford BD. Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication. Toxicology and Applied Pharmacology. 253: 261-9. PMID 21513723 DOI: 10.1016/J.Taap.2011.03.026  0.373
2011 Yang D, Lauridsen H, Buels K, Chi LH, La Du J, Bruun DA, Olson JR, Tanguay RL, Lein PJ. Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 146-59. PMID 21346248 DOI: 10.1093/Toxsci/Kfr028  0.413
2011 Rohlman DS, Anger WK, Lein PJ. Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure. Neurotoxicology. 32: 268-76. PMID 21182866 DOI: 10.1016/J.Neuro.2010.12.008  0.304
2011 Abdu E, Bruun DA, Yang D, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. Journal of Neurochemistry. 117: 632-42. PMID 21155804 DOI: 10.1111/J.1471-4159.2010.07139.X  0.404
2011 Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environmental Health Perspectives. 119: 519-26. PMID 21106467 DOI: 10.1289/Ehp.1002728  0.549
2010 Proskocil BJ, Bruun DA, Thompson CM, Fryer AD, Lein PJ. Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms. Plos One. 5: e10562. PMID 20479945 DOI: 10.1371/Journal.Pone.0010562  0.506
2010 Pessah IN, Cherednichenko G, Lein PJ. Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacology & Therapeutics. 125: 260-85. PMID 19931307 DOI: 10.1016/J.Pharmthera.2009.10.009  0.546
2010 Lein PJ, Fryer AD, Higgins D. Cell Culture: Autonomic and Enteric Neurons Encyclopedia of Neuroscience. 625-632. DOI: 10.1016/B978-008045046-9.00626-4  0.551
2010 Lein PJ, Kim KH, Berman RF, Pessah IN. Exposure of the developing brain to polychlorinated biphenyls influences the susceptibility of the adult brain to stress Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies, and Mechanisms. 211-229. DOI: 10.1002/9780470917060.ch12  0.427
2009 Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 30: 811-21. PMID 19596370 DOI: 10.1016/J.Neuro.2009.07.002  0.507
2009 Yang D, Kim KH, Phimister A, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PR, Anderson KA, Wayman G, Pessah IN, Lein PJ. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environmental Health Perspectives. 117: 426-35. PMID 19337518 DOI: 10.1289/Ehp.11771  0.653
2009 Kim WY, Gonsiorek EA, Barnhart C, Davare MA, Engebose AJ, Lauridsen H, Bruun D, Lesiak A, Wayman G, Bucelli R, Higgins D, Lein PJ. Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. Journal of Neurochemistry. 108: 1057-71. PMID 19209406 DOI: 10.1111/J.1471-4159.2008.05854.X  0.789
2008 Andres DA, Shi GX, Bruun D, Barnhart C, Lein PJ. Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation. Journal of Neurochemistry. 107: 1436-47. PMID 18957053 DOI: 10.1111/J.1471-4159.2008.05708.X  0.494
2008 Boswell BA, Lein PJ, Musil LS. Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells. Molecular Biology of the Cell. 19: 2631-41. PMID 18400943 DOI: 10.1091/Mbc.E08-02-0124  0.338
2008 Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 29: 532-45. PMID 18394707 DOI: 10.1016/J.Neuro.2008.02.006  0.496
2008 Proskocil BJ, Bruun DA, Lorton JK, Blensly KC, Jacoby DB, Lein PJ, Fryer AD. Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity. Environmental Health Perspectives. 116: 381-8. PMID 18335107 DOI: 10.1289/Ehp.10694  0.466
2008 Bucelli RC, Gonsiorek EA, Kim WY, Bruun D, Rabin RA, Higgins D, Lein PJ. Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons. The Journal of Pharmacology and Experimental Therapeutics. 324: 1172-80. PMID 18079356 DOI: 10.1124/Jpet.107.132795  0.767
2008 Yang D, Howard A, Bruun D, Ajua-Alemanj M, Pickart C, Lein PJ. Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase. Toxicology and Applied Pharmacology. 228: 32-41. PMID 18076960 DOI: 10.1016/J.Taap.2007.11.005  0.439
2007 Lein PJ, Guo X, Shi GX, Moholt-Siebert M, Bruun D, Andres DA. The novel GTPase Rit differentially regulates axonal and dendritic growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4725-36. PMID 17460085 DOI: 10.1523/Jneurosci.5633-06.2007  0.499
2007 Lein PJ, Yang D, Bachstetter AD, Tilson HA, Harry GJ, Mervis RF, Kodavanti PR. Ontogenetic alterations in molecular and structural correlates of dendritic growth after developmental exposure to polychlorinated biphenyls. Environmental Health Perspectives. 115: 556-63. PMID 17450224 DOI: 10.1289/Ehp.9773  0.447
2006 Pin S, Chen H, Lein PJ, Wang MM. Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism. Journal of Neurochemistry. 96: 1253-66. PMID 16441515 DOI: 10.1111/J.1471-4159.2006.03653.X  0.382
2005 Howard AS, Bucelli R, Jett DA, Bruun D, Yang D, Lein PJ. Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures. Toxicology and Applied Pharmacology. 207: 112-24. PMID 16102564 DOI: 10.1016/J.Taap.2004.12.008  0.713
2005 Lein PJ, Fryer AD. Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition. Toxicological Sciences : An Official Journal of the Society of Toxicology. 83: 166-76. PMID 15470232 DOI: 10.1093/Toxsci/Kfi001  0.501
2004 Shen W, Finnegan S, Lein P, Sullivan S, Slaughter M, Higgins D. Bone morphogenetic proteins regulate ionotropic glutamate receptors in human retina. The European Journal of Neuroscience. 20: 2031-7. PMID 15450082 DOI: 10.1111/J.1460-9568.2004.03681.X  0.465
2004 Kim IJ, Drahushuk KM, Kim WY, Gonsiorek EA, Lein P, Andres DA, Higgins D. Extracellular signal-regulated kinases regulate dendritic growth in rat sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3304-12. PMID 15056710 DOI: 10.1523/Jneurosci.3286-03.2004  0.771
2004 Fryer AD, Lein PJ, Howard AS, Yost BL, Beckles RA, Jett DA. Mechanisms of organophosphate insecticide-induced airway hyperreactivity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L963-9. PMID 14704222 DOI: 10.1152/Ajplung.00343.2003  0.505
2003 Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicology and Applied Pharmacology. 190: 72-86. PMID 12831785 DOI: 10.1016/S0041-008X(03)00156-X  0.611
2002 Lein PJ, Beck HN, Chandrasekaran V, Gallagher PJ, Chen HL, Lin Y, Guo X, Kaplan PL, Tiedge H, Higgins D. Glia induce dendritic growth in cultured sympathetic neurons by modulating the balance between bone morphogenetic proteins (BMPs) and BMP antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10377-87. PMID 12451137 DOI: 10.1523/Jneurosci.22-23-10377.2002  0.603
2002 Roth JA, Horbinski C, Higgins D, Lein P, Garrick MD. Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation. Neurotoxicology. 23: 147-57. PMID 12224755 DOI: 10.1016/S0161-813X(01)00077-8  0.637
2002 Schuh RA, Lein PJ, Beckles RA, Jett DA. Noncholinesterase mechanisms of chlorpyrifos neurotoxicity: altered phosphorylation of Ca2+/cAMP response element binding protein in cultured neurons. Toxicology and Applied Pharmacology. 182: 176-85. PMID 12140181 DOI: 10.1006/Taap.2002.9445  0.45
2002 Kim IJ, Beck HN, Lein PJ, Higgins D. Interferon gamma induces retrograde dendritic retraction and inhibits synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4530-9. PMID 12040060  0.644
2002 Lein PJ, Beck HN, Chandrasekaran V, Gallagher PJ, Chen H, Lin Y, Guo X, Kaplan PL, Tiedge H, Higgins D. Glia Induce Dendritic Growth in Cultured Sympathetic Neurons by Modulating the Balance between Bone Morphogenetic Proteins (BMPs) and BMP Antagonists The Journal of Neuroscience. 22: 10377-10387. DOI: 10.1523/JNEUROSCI.22-23-10377.2002  0.47
2002 Kim I, Beck HN, Lein PJ, Higgins D. Interferon γ Induces Retrograde Dendritic Retraction and Inhibits Synapse Formation The Journal of Neuroscience. 22: 4530-4539. DOI: 10.1523/Jneurosci.22-11-04530.2002  0.577
2001 Dattatreyamurty B, Roux E, Horbinski C, Kaplan PL, Robak LA, Beck HN, Lein P, Higgins D, Chandrasekaran V. Cerebrospinal fluid contains biologically active bone morphogenetic protein-7. Experimental Neurology. 172: 273-81. PMID 11716552 DOI: 10.1006/Exnr.2001.7728  0.657
2001 Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ. Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. Bmc Neuroscience. 2: 12. PMID 11580864 DOI: 10.1186/1471-2202-2-12  0.796
2001 Guo X, Lin Y, Horbinski C, Drahushuk KM, Kim IJ, Kaplan PL, Lein P, Wang T, Higgins D. Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity. Journal of Neurobiology. 48: 120-30. PMID 11438941 DOI: 10.1002/Neu.1046  0.776
1999 Guo X, Chandrasekaran V, Lein P, Kaplan PL, Higgins D. Leukemia inhibitory factor and ciliary neurotrophic factor cause dendritic retraction in cultured rat sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2113-21. PMID 10066264 DOI: 10.1523/Jneurosci.19-06-02113.1999  0.565
1998 Gadient RA, Lein P, Higgins D, Patterson PH. Effect of leukemia inhibitory factor (LIF) on the morphology and survival of cultured hippocampal neurons and glial cells. Brain Research. 798: 140-6. PMID 9666105 DOI: 10.1016/S0006-8993(98)00236-4  0.559
1997 Guo X, Metzler-Northrup J, Lein P, Rueger D, Higgins D. Leukemia inhibitory factor and ciliary neurotrophic factor regulate dendritic growth in cultures of rat sympathetic neurons. Brain Research. Developmental Brain Research. 104: 101-10. PMID 9466712 DOI: 10.1016/S0165-3806(97)00142-9  0.594
1997 Higgins D, Burack M, Lein P, Banker G. Mechanisms of neuronal polarity. Current Opinion in Neurobiology. 7: 599-604. PMID 9384542 DOI: 10.1016/S0959-4388(97)80078-5  0.538
1996 Lein P, Higgins D. Antibodies to β1 integrins inhibit dendritic growth in rat sympathetic neurons. Biomedical Research (Aligarh, India). 7: 101-111. PMID 29238133  0.49
1996 Lein P, Guo X, Hedges AM, Rueger D, Johnson M, Higgins D. The effects of extracellular matrix and osteogenic protein-1 on the morphological differentiation of rat sympathetic neurons. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 14: 203-15. PMID 8842799 DOI: 10.1016/0736-5748(96)00008-1  0.581
1995 Lein P, Johnson M, Guo X, Rueger D, Higgins D. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons. Neuron. 15: 597-605. PMID 7546739 DOI: 10.1016/0896-6273(95)90148-5  0.589
1992 Lein PJ, Banker GA, Higgins D. Laminin selectively enhances axonal growth and accelerates the development of polarity by hippocampal neurons in culture. Brain Research. Developmental Brain Research. 69: 191-7. PMID 1424096 DOI: 10.1016/0165-3806(92)90159-T  0.529
1991 Lein PJ, Higgins D, Turner DC, Flier LA, Terranova VP. The NC1 domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin. The Journal of Cell Biology. 113: 417-28. PMID 2010469 DOI: 10.1083/Jcb.113.2.417  0.531
1991 Lein PJ, Higgins D. Protein synthesis is required for the initiation of dendritic growth in embryonic rat sympathetic neurons in vitro. Brain Research. Developmental Brain Research. 60: 187-96. PMID 1716531 DOI: 10.1016/0165-3806(91)90047-M  0.547
1990 Bruckenstein DA, Lein PJ, Higgins D, Fremeau RT. Distinct spatial localization of specific mRNAs in cultured sympathetic neurons. Neuron. 5: 809-19. PMID 2148487 DOI: 10.1016/0896-6273(90)90340-L  0.489
1989 Lein PJ, Higgins D. Laminin and a basement membrane extract have different effects on axonal and dendritic outgrowth from embryonic rat sympathetic neurons in vitro. Developmental Biology. 136: 330-45. PMID 2479584 DOI: 10.1016/0012-1606(89)90260-1  0.56
1988 Kung MP, Nickerson PA, Sansone FM, Olson JR, Kostyniak PJ, Adolf MA, Lein PJ, Roth JA. Effect of short-term exposure to hexachlorophene on rat brain cell specific marker enzymes. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 11: 519-27. PMID 2906023 DOI: 10.1016/0272-0590(88)90116-9  0.339
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