Daniel L. Alkon - Publications

Affiliations: 
Blanchette Rockefeller Neurosciences Institute, Morgantown, WV, United States 
Area:
Memory and Memory Disorders
Website:
http://www.brni.org/experts/danielalkonmd.aspx

126/382 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Connor JH, Olds JL, Lester DS, McPhie DL, Senft SL, Johnston JA, Alkon DL. Heterogenous Distribution of Fluorescent Phorbol Ester Signal in Living Sea Urchin Embryos. The Biological Bulletin. 183: 365-366. PMID 29300655 DOI: 10.1086/Bblv183N2P365  0.547
2015 Denvir J, Neitch S, Fan J, Niles RM, Boskovic G, Schreurs BG, Primerano DA, Alkon DL. Identification of the PS1 Thr147Ile Variant in a Family with Very Early Onset Dementia and Expressive Aphasia. Journal of Alzheimer's Disease : Jad. PMID 25812849 DOI: 10.3233/Jad-150051  0.491
2008 Wang D, Darwish DS, Schreurs BG, Alkon DL. Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response. Behavioural Pharmacology. 19: 245-56. PMID 18469542 DOI: 10.1097/Fbp.0B013E3282Feb0D2  0.61
2004 Pascale A, Alkon DL, Grimaldi M. Translocation of protein kinase C-betaII in astrocytes requires organized actin cytoskeleton and is not accompanied by synchronous RACK1 relocation. Glia. 46: 169-82. PMID 15042584 DOI: 10.1002/glia.10354  0.338
2003 Zhao WQ, Alkon DL, Ma W. c-Src protein tyrosine kinase activity is required for muscarinic receptor-mediated DNA synthesis and neurogenesis via ERK1/2 and c-AMP-responsive element-binding protein signaling in neural precursor cells. Journal of Neuroscience Research. 72: 334-42. PMID 12692900 DOI: 10.1002/jnr.10591  0.348
2002 Zhao WQ, Ravindranath L, Mohamed AS, Zohar O, Chen GH, Lyketsos CG, Etcheberrigaray R, Alkon DL. MAP kinase signaling cascade dysfunction specific to Alzheimer's disease in fibroblasts. Neurobiology of Disease. 11: 166-83. PMID 12460556 DOI: 10.1006/nbdi.2002.0520  0.316
2001 Kuzirian AM, Epstein HT, Buck D, Child FM, Nelson T, Alkon DL. Pavlovian conditioning-specific increases of the Ca2+- and GTP-binding protein, calexcitin in identified Hermissenda visual cells. Journal of Neurocytology. 30: 993-1008. PMID 12626881 DOI: 10.1023/A:1021836723609  0.322
2001 Schreurs BG, Alkon DL. Imaging learning and memory: classical conditioning. The Anatomical Record. 265: 257-73. PMID 11753917 DOI: 10.1002/Ar.10031  0.572
2001 Gusev PA, Alkon DL. Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells. Journal of Neurophysiology. 86: 881-99. PMID 11495958 DOI: 10.1152/Jn.2001.86.2.881  0.431
2001 Cavallaro S, Schreurs BG, Zhao W, D'Agata V, Alkon DL. Gene expression profiles during long-term memory consolidation. The European Journal of Neuroscience. 13: 1809-15. PMID 11359532 DOI: 10.1046/J.0953-816X.2001.01543.X  0.572
2001 Sun MK, Zhao WQ, Nelson TJ, Alkon DL. Theta rhythm of hippocampal CA1 neuron activity: gating by GABAergic synaptic depolarization. Journal of Neurophysiology. 85: 269-79. PMID 11152726 DOI: 10.1152/Jn.2001.85.1.269  0.396
2000 Tomsic D, Alkon DL. Background illumination effects upon in vitro conditioning in Hermissenda. Neurobiology of Learning and Memory. 74: 56-64. PMID 10873520 DOI: 10.1006/nlme.1999.3938  0.683
2000 Zhao W, Meiri N, Xu H, Cavallaro S, Quattrone A, Zhang L, Alkon DL. Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 290-300. PMID 10657985 DOI: 10.1096/Fasebj.14.2.290  0.384
1999 Zhao W, Chen H, Xu H, Moore E, Meiri N, Quon MJ, Alkon DL. Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. The Journal of Biological Chemistry. 274: 34893-902. PMID 10574963 DOI: 10.1074/Jbc.274.49.34893  0.395
1999 Grimaldi M, Favit A, Alkon DL. cAMP-induced cytoskeleton rearrangement increases calcium transients through the enhancement of capacitative calcium entry. The Journal of Biological Chemistry. 274: 33557-64. PMID 10559242 DOI: 10.1074/jbc.274.47.33557  0.33
1999 Alkon DL. Ionic conductance determinants of synaptic memory nets and their implications for Alzheimer's disease. Journal of Neuroscience Research. 58: 24-32. PMID 10491569 DOI: 10.1002/(SICI)1097-4547(19991001)58:1<24::AID-JNR4>3.0.CO;2-N  0.376
1999 Nelson TJ, Zhao WQ, Yuan S, Favit A, Pozzo-Miller L, Alkon DL. Calexcitin interaction with neuronal ryanodine receptors. The Biochemical Journal. 341: 423-33. PMID 10393102 DOI: 10.1042/0264-6021:3410423  0.332
1999 Blackwell KT, Alkon DL. Ryanodine receptor modulation of in vitro associative learning in Hermissenda crassicornis. Brain Research. 822: 114-25. PMID 10082889 DOI: 10.1016/S0006-8993(99)01105-1  0.384
1999 Yagodin S, Collin C, Alkon DL, Sheppard NF, Sattelle DB. Mapping membrane potential transients in crayfish (Procambarus clarkii) optic lobe neuropils with voltage-sensitive dyes. Journal of Neurophysiology. 81: 334-44. PMID 9914293 DOI: 10.1152/Jn.1999.81.1.334  0.316
1998 Alkon DL. Molecular specificity of synaptic changes responsible for associative memory. Advances in Experimental Medicine and Biology. 446: 1-15. PMID 10079834 DOI: 10.1007/978-1-4615-4869-0_1  0.413
1998 Alkon DL, Nelson TJ, Zhao W, Cavallaro S. Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade. Trends in Neurosciences. 21: 529-37. PMID 9881851 DOI: 10.1016/S0166-2236(98)01277-6  0.316
1998 Blackwell KT, Vogl TP, Alkon DL. Pattern matching in a model of dendritic spines. Network (Bristol, England). 9: 107-21. PMID 9861981 DOI: 10.1088/0954-898X_9_1_006  0.325
1998 Ascoli GA, Pergami P, Luu KX, Alkon DL, Bramanti E, Bertucci C, Di Bari L, Salvadori P. Use of CD and FT-IR to determine the secondary structure of purified proteins in the low-microgram range. Enantiomer. 3: 371-81. PMID 9861703  0.456
1998 Alkon DL, Favit A, Nelson T. Evolution of adaptive neural networks: the role of voltage-dependent K+ channels. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 119: 204-11. PMID 9743076 DOI: 10.1016/S0194-5998(98)70055-5  0.328
1998 Schreurs BG, Gusev PA, Tomsic D, Alkon DL, Shi T. Intracellular correlates of acquisition and long-term memory of classical conditioning in Purkinje cell dendrites in slices of rabbit cerebellar lobule HVI. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5498-507. PMID 9651230 DOI: 10.1523/Jneurosci.18-14-05498.1998  0.763
1997 Ascoli GA, Luu KX, Olds JL, Nelson TJ, Gusev PA, Bertucci C, Bramanti E, Raffaelli A, Salvadori P, Alkon DL. Secondary structure and Ca2+-induced conformational change of calexcitin, a learning-associated protein. The Journal of Biological Chemistry. 272: 24771-9. PMID 9312073 DOI: 10.1074/Jbc.272.40.24771  0.7
1997 Cavallaro S, Meiri N, Yi CL, Musco S, Ma W, Goldberg J, Alkon DL. Late memory-related genes in the hippocampus revealed by RNA fingerprinting. Proceedings of the National Academy of Sciences of the United States of America. 94: 9669-73. PMID 9275181 DOI: 10.1073/Pnas.94.18.9669  0.546
1997 de Barry J, Kawahara S, Takamura K, Janoshazi A, Kirino Y, Olds JL, Lester DS, Alkon DL, Yoshioka T. Time-resolved imaging of protein kinase C activation during sea urchin egg fertilization. Experimental Cell Research. 234: 115-24. PMID 9223376 DOI: 10.1006/Excr.1997.3597  0.612
1997 Schreurs BG, Tomsic D, Gusev PA, Alkon DL. Dendritic excitability microzones and occluded long-term depression after classical conditioning of the rabbit's nictitating membrane response. Journal of Neurophysiology. 77: 86-92. PMID 9120599 DOI: 10.1152/Jn.1997.77.1.86  0.768
1997 Meiri N, Ghelardini C, Tesco G, Galeotti N, Dahl D, Tomsic D, Cavallaro S, Quattrone A, Capaccioli S, Bartolini A, Alkon DL. Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat. Proceedings of the National Academy of Sciences of the United States of America. 94: 4430-4. PMID 9114006 DOI: 10.1073/Pnas.94.9.4430  0.668
1997 Nelson TJ, Alkon DL. Biochemistry of molluscan learning and memory Bioessays. 19: 1045-1053. DOI: 10.1002/Bies.950191203  0.395
1996 Nelson TJ, Cavallaro S, Yi CL, McPhie D, Schreurs BG, Gusev PA, Favit A, Zohar O, Kim J, Beushausen S, Ascoli G, Olds J, Neve R, Alkon DL. Calexcitin: a signaling protein that binds calcium and GTP, inhibits potassium channels, and enhances membrane excitability. Proceedings of the National Academy of Sciences of the United States of America. 93: 13808-13. PMID 8943017 DOI: 10.1073/Pnas.93.24.13808  0.757
1996 Schreurs BG, Oh MM, Alkon DL. Pairing-specific long-term depression of Purkinje cell excitatory postsynaptic potentials results from a classical conditioning procedure in the rabbit cerebellar slice. Journal of Neurophysiology. 75: 1051-60. PMID 8867117 DOI: 10.1152/Jn.1996.75.3.1051  0.585
1995 Golski S, Olds JL, Mishkin M, Olton DS, Alkon DL. Protein kinase C in the hippocampus is altered by spatial but not cued discriminations: a component task analysis. Brain Research. 676: 53-62. PMID 7796178 DOI: 10.1016/0006-8993(95)00080-A  0.639
1995 Schreurs BG, Oh MM, Hirashima C, Alkon DL. Conditioning-specific modification of the rabbit's unconditioned nictitating membrane response. Behavioral Neuroscience. 109: 24-33. PMID 7734076 DOI: 10.1037/0735-7044.109.1.24  0.637
1995 Kim CS, Han YF, Etcheberrigaray R, Nelson TJ, Olds JL, Yoshioka T, Alkon DL. Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20. Proceedings of the National Academy of Sciences of the United States of America. 92: 3060-4. PMID 7708775 DOI: 10.1073/Pnas.92.7.3060  0.592
1995 Nelson TJ, Alkon DL. Phosphorylation of the conditioning-associated GTP-binding protein cp20 by protein kinase C. Journal of Neurochemistry. 65: 2350-7. PMID 7595525 DOI: 10.1046/J.1471-4159.1995.65052350.X  0.344
1994 Lester DS, Olds JL, Schreurs BG, McPhie D, Bramham CR, Alkon DL. Incorporation of fluorescent lipids into living rabbit hippocampal and cerebellar slices. Neuroimage. 1: 264-75. PMID 9343576 DOI: 10.1006/Nimg.1994.1011  0.767
1994 Ito E, Oka K, Etcheberrigaray R, Nelson TJ, McPhie DL, Tofel-Grehl B, Gibson GE, Alkon DL. Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 534-8. PMID 8290560 DOI: 10.1073/Pnas.91.2.534  0.33
1994 Ito E, Oka K, Collin C, Schreurs BG, Sakakibara M, Alkon DL. Intracellular calcium signals are enhanced for days after Pavlovian conditioning. Journal of Neurochemistry. 62: 1337-44. PMID 8133264 DOI: 10.1046/J.1471-4159.1994.62041337.X  0.655
1994 Olds JL, Bhalla US, McPhie DL, Lester DS, Bower JM, Alkon DL. Lateralization of membrane-associated protein kinase C in rat piriform cortex: specific to operant training cues in the olfactory modality. Behavioural Brain Research. 61: 37-46. PMID 8031495 DOI: 10.1016/0166-4328(94)90006-X  0.612
1994 Bramham CR, Alkon DL, Lester DS. Arachidonic acid and diacylglycerol ACT synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus. Neuroscience. 60: 737-43. PMID 7936199 DOI: 10.1016/0306-4522(94)90501-0  0.602
1994 Etcheberrigaray E, Gibson GE, Alkon DL. Molecular mechanisms of memory and the pathophysiology of Alzheimer's disease. Annals of the New York Academy of Sciences. 747: 245-55. PMID 7847674 DOI: 10.1111/J.1749-6632.1994.Tb44413.X  0.338
1994 Kawahara S, Kirino Y, Sakakibara M, Kudo Y, Takamura K, Inoue H, Yoshioka T, Janoshazi A, de Barry J, Olds JL, Alkon DL. Imaging of intracellular translocation of protein kinase C Neuroscience Research Supplements. 19: S102. DOI: 10.1016/0921-8696(94)92549-6  0.538
1993 Alkon DL, Collin C, Ito E, Lee CJ, Nelson TJ, Oka K, Sakakibara M, Schreurs BG, Yoshioka T. Molecular and biophysical steps in the storage of associative memory. Annals of the New York Academy of Sciences. 707: 500-4. PMID 9137606 DOI: 10.1111/J.1749-6632.1993.Tb38109.X  0.583
1993 Sunayashiki-Kusuzaki K, Lester DS, Schreurs BG, Alkon DL. Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 90: 4286-9. PMID 8483944 DOI: 10.1073/Pnas.90.9.4286  0.672
1993 McPhie DL, Matzel LD, Olds JL, Lester DS, Kuzirian AM, Alkon DL. Cell specificity of molecular changes during memory storage. Journal of Neurochemistry. 60: 646-51. PMID 8419542 DOI: 10.1111/J.1471-4159.1993.Tb03196.X  0.74
1993 Sanchez-Andres JV, Olds JL, Alkon DL. Gated informational transfer within the mammalian hippocampus: a new hypothesis. Behavioural Brain Research. 54: 111-6. PMID 8391823 DOI: 10.1016/0166-4328(93)90069-3  0.575
1993 Alkon DL, Anderson MJ, Kuzirian AJ, Rogers DF, Fass DM, Collin C, Nelson TJ, Kapetanovic IM, Matzel LD. GABA-mediated synaptic interaction between the visual and vestibular pathways of Hermissenda. Journal of Neurochemistry. 61: 556-66. PMID 8336142  0.587
1993 Werness SA, Fay SD, Blackwell KT, Vogl TP, Alkon DL. Associative learning in a network model of Hermissenda crassicornis. II. Experiments. Biological Cybernetics. 69: 19-28. PMID 8334187 DOI: 10.1007/Bf00201405  0.356
1993 Olds JL, Alkon DL. Protein kinase C: a nexus in the biochemical events that underlie associative learning. Acta Neurobiologiae Experimentalis. 53: 197-207. PMID 8317248  0.598
1993 Craig AM, Olds JL, Schreurs BG, Scharenberg AM, Alkon DL. Quantitative distribution of protein kinase C alpha, beta, gamma, and epsilon mRNAs in the hippocampus of control and nictitating membrane conditioned rabbits. Brain Research. Molecular Brain Research. 19: 269-76. PMID 8231730 DOI: 10.1016/0169-328X(93)90125-9  0.721
1993 Schreurs BG, Alkon DL. Rabbit cerebellar slice analysis of long-term depression and its role in classical conditioning. Brain Research. 631: 235-40. PMID 8131052 DOI: 10.1016/0006-8993(93)91540-9  0.548
1992 Etcheberrigaray R, Matzel LD, Lederhendler II, Alkon DL. Classical conditioning and protein kinase C activation regulate the same single potassium channel in Hermissenda crassicornis photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 7184-8. PMID 1496012 DOI: 10.1073/pnas.89.15.7184  0.586
1992 Werness SA, Fay SD, Blackwell KT, Vogl TP, Alkon DL. Associative learning in a network model of Hermissenda crassicornis. I. Theory. Biological Cybernetics. 68: 125-33. PMID 1486137 DOI: 10.1007/Bf00201434  0.327
1992 Collin C, Ito E, Oka K, Yoshioka T, Sánchez-Andrés JV, Matzel LD, Alkon DL. The role of calcium in prolonged modification of a GABAergic synapse. Journal of Physiology, Paris. 86: 139-45. PMID 1343591 DOI: 10.1016/S0928-4257(05)80019-1  0.618
1992 Schreurs BG, Sanchez-Andres JV, Alkon DL. GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice. Brain Research. 597: 99-107. PMID 1335825 DOI: 10.1016/0006-8993(92)91510-L  0.613
1992 Matzel LD, Collin C, Alkon DL. Biophysical and behavioral correlates of memory storage, degradation, and reactivation. Behavioral Neuroscience. 106: 954-63. PMID 1335270 DOI: 10.1037/0735-7044.106.6.954  0.623
1992 Alkon DL, Sánchez-Andrés JV, Ito E, Oka K, Yoshioka T, Collin C. Long-term transformation of an inhibitory into an excitatory GABAergic synaptic response. Proceedings of the National Academy of Sciences of the United States of America. 89: 11862-6. PMID 1334550 DOI: 10.1073/Pnas.89.24.11862  0.36
1992 Vogl TP, Blackwell KL, Barbour G, Alkon DL. Dynamically stable associative learning: a neurobiologically based ANN and its applications Proceedings of Spie. 1710: 165-176. DOI: 10.1117/12.140082  0.357
1992 Oka K, Ito E, Collin C, Schreurs BG, Yoshioka T, Alkon DL. Synaptic mechanisms of associative memory storage in biological and artificial networks Neuroscience Research Supplements. 17: 289. DOI: 10.1016/0921-8696(92)91250-A  0.556
1991 Olds JL, Alkon DL. A role for protein kinase C in associative learning. The New Biologist. 3: 27-35. PMID 2039766  0.603
1991 Nelson TJ, Sanchez-Andres JV, Schreurs BG, Alkon DL. Classical conditioning-induced changes in low-molecular-weight GTP-binding proteins in rabbit hippocampus. Journal of Neurochemistry. 57: 2065-9. PMID 1940916 DOI: 10.1111/J.1471-4159.1991.Tb06423.X  0.625
1991 Schreurs BG, Sanchez-Andres JV, Alkon DL. Learning-specific differences in Purkinje-cell dendrites of lobule HVI (Lobulus simplex): intracellular recording in a rabbit cerebellar slice. Brain Research. 548: 18-22. PMID 1868333 DOI: 10.1016/0006-8993(91)91100-F  0.629
1991 Scharenberg AM, Olds JL, Schreurs BG, Craig AM, Alkon DL. Protein kinase C redistribution within CA3 stratum oriens during acquisition of nictitating membrane conditioning in the rabbit. Proceedings of the National Academy of Sciences of the United States of America. 88: 6637-41. PMID 1862086 DOI: 10.1073/Pnas.88.15.6637  0.732
1991 Alkon DL, Matzel LD, Collin C. Molecular mechanisms of memory and drug dependence. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 1: 35-7. PMID 1845561  0.631
1991 Nelson TJ, Alkon DL. GTP-binding proteins and potassium channels involved in synaptic plasticity and learning. Molecular Neurobiology. 5: 315-28. PMID 1823140 DOI: 10.1007/BF02935554  0.339
1991 Lester DS, Alkon DL. Activation of protein kinase C phosphorylation pathways: a role for storage of associative memory. Progress in Brain Research. 89: 235-48. PMID 1796141 DOI: 10.1016/S0079-6123(08)61725-2  0.426
1991 Matzel LD, Alkon DL. GABA-induced potentiation of neuronal excitability occurs during contiguous pairings with intracellular calcium elevation. Brain Research. 554: 77-84. PMID 1718551 DOI: 10.1016/0006-8993(91)90174-T  0.606
1990 Matzel LD, Lederhendler II, Alkon DL. Regulation of short-term associative memory by calcium-dependent protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2300-7. PMID 2376776 DOI: 10.1523/Jneurosci.10-07-02300.1990  0.687
1990 Alkon DL, Ikeno H, Dworkin J, McPhie DL, Olds JL, Lederhendler I, Matzel L, Schreurs BG, Kuzirian A, Collin C. Contraction of neuronal branching volume: an anatomic correlate of Pavlovian conditioning. Proceedings of the National Academy of Sciences of the United States of America. 87: 1611-4. PMID 2304920 DOI: 10.1073/Pnas.87.4.1611  0.794
1990 Matzel LD, Schreurs BG, Alkon DL. Pavlovian conditioning of distinct components of Hermissenda's responses to rotation. Behavioral and Neural Biology. 54: 131-45. PMID 2241759 DOI: 10.1016/0163-1047(90)91324-5  0.724
1990 Olds JL, Golski S, McPhie DL, Olton D, Mishkin M, Alkon DL. Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3707-13. PMID 2230955 DOI: 10.1523/Jneurosci.10-11-03707.1990  0.583
1990 Matzel LD, Schreurs BG, Lederhendler I, Alkon DL. Acquisition of conditioned associations in Hermissenda: additive effects of contiguity and the forward interstimulus interval. Behavioral Neuroscience. 104: 597-606. PMID 2206429 DOI: 10.1037//0735-7044.104.4.597  0.712
1990 Nelson TJ, Collin C, Alkon DL. Isolation of a G protein that is modified by learning and reduces potassium currents in Hermissenda. Science (New York, N.Y.). 247: 1479-83. PMID 2108498  0.313
1990 Alkon DL, Nelson TJ. Specificity of molecular changes in neurons involved in memory storage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 1567-76. PMID 2108074 DOI: 10.1096/Fasebj.4.6.2108074  0.381
1990 Lederhendler II, Etcheberrigaray R, Yamoah EN, Matzel LD, Alkon DL. Outgrowths from Hermissenda photoreceptor somata are associated with activation of protein kinase C. Brain Research. 534: 195-200. PMID 2073581 DOI: 10.1016/0006-8993(90)90129-Y  0.686
1990 Schreurs BG, Alkon DL. US-US conditioning of the rabbit’s nictitating membrane response: Emergence of a conditioned response without alpha conditioning Psychobiology. 18: 312-320. DOI: 10.3758/Bf03327249  0.638
1989 Akase E, Alkon DL, Disterhoft JF. Hippocampal lesions impair memory of short-delay conditioned eye blink in rabbits. Behavioral Neuroscience. 103: 935-43. PMID 2803560 DOI: 10.1037/0735-7044.103.5.935  0.376
1989 Olds JL, Anderson ML, McPhie DL, Staten LD, Alkon DL. Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus. Science (New York, N.Y.). 245: 866-9. PMID 2772638 DOI: 10.1126/Science.2772638  0.665
1989 Bank B, LoTurco JJ, Alkon DL. Learning-induced activation of protein kinase C. A molecular memory trace. Molecular Neurobiology. 3: 55-70. PMID 2679767 DOI: 10.1007/BF02935588  0.428
1989 Coulter DA, Lo Turco JJ, Kubota M, Disterhoft JF, Moore JW, Alkon DL. Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells. Journal of Neurophysiology. 61: 971-81. PMID 2542473 DOI: 10.1152/Jn.1989.61.5.971  0.62
1988 Naito S, Bank B, Alkon DL. Transient and persistent depolarization-induced changes of protein phosphorylation in a molluscan nervous system. Journal of Neurochemistry. 50: 704-11. PMID 3276816 DOI: 10.1111/J.1471-4159.1988.Tb02971.X  0.344
1988 Disterhoft JF, Golden DT, Read HL, Coulter DA, Alkon DL. AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response. Brain Research. 462: 118-25. PMID 3179727 DOI: 10.1016/0006-8993(88)90593-8  0.597
1988 Bank B, DeWeer A, Kuzirian AM, Rasmussen H, Alkon DL. Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 1988-92. PMID 3162320 DOI: 10.1073/Pnas.85.6.1988  0.306
1988 LoTurco JL, Coulter DA, Alkon DL. Enhancement of synaptic potentials in rabbit CA1 pyramidal neurons following classical conditioning. Proceedings of the National Academy of Sciences of the United States of America. 85: 1672-6. PMID 2830626 DOI: 10.1073/Pnas.85.5.1672  0.615
1988 Alkon DL, Naito S, Kubota M, Chen C, Bank B, Smallwood J, Gallant P, Rasmussen H. Regulation of Hermissenda K+ channels by cytoplasmic and membrane-associated C-kinase. Journal of Neurochemistry. 51: 903-17. PMID 2457656 DOI: 10.1111/J.1471-4159.1988.Tb01827.X  0.393
1987 Lederhendler II, Alkon DL. Associatively reduced withdrawal from shadows in Hermissenda: a direct behavioral analog of photoreceptor responses to brief light steps. Behavioral and Neural Biology. 47: 227-49. PMID 3606526 DOI: 10.1016/S0163-1047(87)90370-0  0.378
1987 Farley J, Alkon DL. In vitro associative conditioning of Hermissenda: cumulative depolarization of type B photoreceptors and short-term associative behavioral changes. Journal of Neurophysiology. 57: 1639-68. PMID 3598626  0.458
1987 Sakakibara M, Collin C, Kuzirian A, Alkon DL, Heldman E, Naito S, Lederhendler I. Effects of alpha 2-adrenergic agonists and antagonists on photoreceptor membrane currents. Journal of Neurochemistry. 48: 405-16. PMID 2878978 DOI: 10.1111/j.1471-4159.1987.tb04108.x  0.396
1986 Alkon DL, Kubota M, Neary JT, Naito S, Coulter D, Rasmussen H. C-kinase activation prolongs Ca2+-dependent inactivation of K+ currents. Biochemical and Biophysical Research Communications. 134: 1245-53. PMID 3790201 DOI: 10.1016/0006-291X(86)90384-0  0.637
1986 Neary JT, Naito S, De Weer A, Alkon DL. Ca2+/diacylglycerol-activated, phospholipid-dependent protein kinase in the Hermissenda CNS. Journal of Neurochemistry. 47: 1405-11. PMID 3760869 DOI: 10.1111/j.1471-4159.1986.tb00772.x  0.355
1986 Alkon DL, Sakakibara M, Naito S, Heldman E, Lederhendler I. The role of neurochemical modulation in learning. Neuroscience Research. 3: 487-97. PMID 3534645 DOI: 10.1016/0168-0102(86)90049-0  0.443
1986 Sakakibara M, Alkon DL, Neary JT, Heldman E, Gould R. Inositol trisphosphate regulation of photoreceptor membrane currents. Biophysical Journal. 50: 797-803. PMID 3491632 DOI: 10.1016/S0006-3495(86)83520-2  0.332
1986 Disterhoft JF, Coulter DA, Alkon DL. Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro. Proceedings of the National Academy of Sciences of the United States of America. 83: 2733-7. PMID 3458232 DOI: 10.1073/Pnas.83.8.2733  0.646
1986 Alkon DL, Naito S. Biochemical mechanisms of memory storage. Journal De Physiologie. 81: 252-60. PMID 2437294  0.319
1986 Neary JT, Alkon DL. Protein phosphorylation and associative learning in Hermissenda. Acta Biochimica Et Biophysica Hungarica. 21: 159-76. PMID 2432746  0.309
1986 Kuzirian A, Meyhöfer E, Hill L, Neary JT, Alkon DL. Autoradiographic measurement of tritiated agmatine as an indicator of physiologic activity in Hermissenda visual and vestibular neurons. Journal of Neurocytology. 15: 629-43. PMID 2430069 DOI: 10.1007/BF01611862  0.334
1986 Sakakibara M, Alkon DL, DeLorenzo R, Goldenring JR, Neary JT, Heldman E. Modulation of calcium-mediated inactivation of ionic currents by Ca2+/calmodulin-dependent protein kinase II. Biophysical Journal. 50: 319-27. PMID 2427133 DOI: 10.1016/S0006-3495(86)83465-8  0.354
1986 HARRIGAN JF, CROW TJ, KUZIRIAN AM, ALKON DL. BEHAVIORAL, ELECTROPHYSIOLOGICAL, AND MORPHOLOGICAL INVESTIGATIONS OF STATOCYST FUNCTION IN THE NUDIBRANCH MOLLUSCHERMISSENDA CRASSICORNIS The Biological Bulletin. 170: 305-320. DOI: 10.2307/1541811  0.319
1985 Alkon DL, Sakakibara M, Forman R, Harrigan J, Lederhendler I, Farley J. Reduction of two voltage-dependent K+ currents mediates retention of a learned association. Behavioral and Neural Biology. 44: 278-300. PMID 4062781  0.444
1985 Farley J, Alkon DL. Cellular mechanisms of learning, memory, and information storage. Annual Review of Psychology. 36: 419-94. PMID 2983604 DOI: 10.1146/annurev.ps.36.020185.002223  0.477
1985 HARRIGAN JF, ALKON DL. INDIVIDUAL VARIATION IN ASSOCIATIVE LEARNING OF THE NUDIBRANCH MOLLUSCHERMISSENDA CRASSICORNIS The Biological Bulletin. 168: 222-238. DOI: 10.2307/1541236  0.309
1984 Richards WG, Farley J, Alkon DL. Extinction of associative learning in Hermissenda: behavior and neural correlates. Behavioural Brain Research. 14: 161-70. PMID 6525240 DOI: 10.1016/0166-4328(84)90185-2  0.439
1984 Woody CD, Alkon DL, Hay B. Depolarization-induced effects of Ca2+-calmodulin-dependent protein kinase injection, in vivo, in single neurons of cat motor cortex. Brain Research. 321: 192-7. PMID 6498512 DOI: 10.1016/0006-8993(84)90701-7  0.381
1984 Alkon DL, Farley J, Sakakibara M, Hay B. Voltage-dependent calcium and calcium-activated potassium currents of a molluscan photoreceptor. Biophysical Journal. 46: 605-14. PMID 6498273 DOI: 10.1016/S0006-3495(84)84059-X  0.475
1984 Acosta-Urquidi J, Alkon DL, Neary JT. Ca2+-dependent protein kinase injection in a photoreceptor mimics biophysical effects of associative learning. Science (New York, N.Y.). 224: 1254-7. PMID 6328653 DOI: 10.1126/science.6328653  0.415
1984 Alkon DL. Calcium-mediated reduction of ionic currents: a biophysical memory trace. Science (New York, N.Y.). 226: 1037-45. PMID 6093258 DOI: 10.1126/Science.6093258  0.418
1983 Farley J, Richards WG, Ling LJ, Liman E, Alkon DL. Membrane changes in a single photoreceptor cause associative learning in Hermissenda. Science (New York, N.Y.). 221: 1201-3. PMID 6612335 DOI: 10.1126/Science.6612335  0.511
1983 Alkon DL, Acosta-Urquidi J, Olds J, Kuzma G, Neary JT. Protein kinase injection reduces voltage-dependent potassium currents. Science (New York, N.Y.). 219: 303-6. PMID 6294830 DOI: 10.1126/Science.6294830  0.63
1982 Alkon DL. Regenerative changes of voltage-dependent Ca2+ and K+ currents encode a learned stimulus association. Journal De Physiologie. 78: 700-6. PMID 7187444  0.311
1982 Farley J, Alkon DL. Associative neural and behavioral change in Hermissenda: consequences of nervous system orientation for light and pairing specificity. Journal of Neurophysiology. 48: 785-807. PMID 6290619  0.347
1982 Takeda T, Alkon DL. Correlated receptor and motorneuron changes during retention of associative learning of Hermissenda crassicornis. Comparative Biochemistry and Physiology. a, Comparative Physiology. 73: 151-7. PMID 6128102 DOI: 10.1016/0300-9629(82)90048-2  0.382
1981 Neary JT, Crow T, Alkon DL. Change in a specific phosphoprotein band following associative learning in Hermissenda. Nature. 293: 658-60. PMID 7290202 DOI: 10.1038/293658a0  0.373
1980 Farley J, Alkon DL. Neural organization predicts stimulus specificity for a retained associative behavioral change. Science (New York, N.Y.). 210: 1373-5. PMID 7434033 DOI: 10.1126/Science.7434033  0.459
1980 ALKON DL. CELLULAR ANALYSIS OF A GASTROPOD (HERMISSENDA CRASSICORNIS) MODEL OF ASSOCIATIVE LEARNING The Biological Bulletin. 159: 505-560. DOI: 10.2307/1540821  0.368
1979 Alkon DL. Voltage-dependent calcium and potassium ion conductances: a contingency mechanism for an associative learning model. Science (New York, N.Y.). 205: 810-6. PMID 223244 DOI: 10.1126/Science.223244  0.401
1978 Crow TJ, Alkon DL. Retention of an associative behavioral change in Hermissenda. Science (New York, N.Y.). 201: 1239-41. PMID 694512 DOI: 10.1126/Science.694512  0.329
1978 Alkon DL, Akaike T, Harrigan J. Interaction of chemosensory, visual, and statocyst pathways in Hermissenda crassicornis. The Journal of General Physiology. 71: 177-94. PMID 641519 DOI: 10.1085/Jgp.71.2.177  0.314
1976 Alkon DL. Signal transformation with pairing of sensory stimuli. The Journal of General Physiology. 67: 197-211. PMID 1255126 DOI: 10.1085/Jgp.67.2.197  0.308
1976 Alkon DL. Neural modification by paired sensory stimuli. The Journal of General Physiology. 68: 341-58. PMID 956091 DOI: 10.1085/Jgp.68.3.341  0.342
1975 Alkon DL. Neural correlates of associative training in Hermissenda. The Journal of General Physiology. 65: 46-56. PMID 1110353 DOI: 10.1085/Jgp.65.1.46  0.338
1974 Alkon DL. Associative training of Hermissenda. The Journal of General Physiology. 64: 70-84. PMID 4837687 DOI: 10.1085/Jgp.64.1.70  0.306
1973 Alkon DL, Bak A. Hair cell generator potentials. The Journal of General Physiology. 61: 619-37. PMID 4705640 DOI: 10.1085/Jgp.61.5.619  0.316
1973 Detwiler PB, Alkon DL. Hair cell interactions in the statocyst of Hermissenda. The Journal of General Physiology. 62: 618-42. PMID 4356414 DOI: 10.1085/Jgp.62.5.618  0.333
1973 Alkon DL. Intersensory interactions in Hermissenda. The Journal of General Physiology. 62: 185-202. PMID 4352950 DOI: 10.1085/Jgp.62.2.185  0.316
Low-probability matches (unlikely to be authored by this person)
2014 Xu C, Liu QY, Alkon DL. PKC activators enhance GABAergic neurotransmission and paired-pulse facilitation in hippocampal CA1 pyramidal neurons. Neuroscience. 268: 75-86. PMID 24637095 DOI: 10.1016/j.neuroscience.2014.03.008  0.299
2006 Kuzirian AM, Epstein HT, Gagliardi CJ, Nelson TJ, Sakakibara M, Taylor C, Scioletti AB, Alkon DL. Bryostatin enhancement of memory in Hermissenda. The Biological Bulletin. 210: 201-14. PMID 16801495 DOI: 10.2307/4134558  0.298
1975 Alkon DL. Responses of hair cells to statocyst rotation. The Journal of General Physiology. 66: 507-30. PMID 171331 DOI: 10.1085/Jgp.66.4.507  0.296
1995 Luo YQ, Hirashima N, Li YH, Alkon DL, Sunderland T, Etcheberrigaray R, Wolozin B. Physiological levels of beta-amyloid increase tyrosine phosphorylation and cytosolic calcium. Brain Research. 681: 65-74. PMID 7552293 DOI: 10.1016/0006-8993(95)00282-U  0.295
1984 Alkon DL. Changes of membrane currents during learning. The Journal of Experimental Biology. 112: 95-112. PMID 6150967  0.294
1987 Alkon DL, Naito S. Long-term synergistic regulation of ionic channels by C-kinase and Ca2+/CaM-type II kinase. Advances in Experimental Medicine and Biology. 221: 275-90. PMID 2449050 DOI: 10.1007/978-1-4684-7618-7_20  0.294
1996 Etcheberrigaray R, Payne JL, Alkon DL. Soluble beta-amyloid induces Alzheimer's disease features in human fibroblasts and in neuronal tissues. Life Sciences. 59: 491-8. PMID 8761337 DOI: 10.1016/0024-3205(96)00328-1  0.293
2000 Zhao W, Cavallaro S, Gusev P, Alkon DL. Nonreceptor tyrosine protein kinase pp60c-src in spatial learning: synapse-specific changes in its gene expression, tyrosine phosphorylation, and protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 97: 8098-103. PMID 10884433 DOI: 10.1073/pnas.97.14.8098  0.292
1996 Hirashima N, Etcheberrigaray R, Bergamaschi S, Racchi M, Battaini F, Binetti G, Govoni S, Alkon DL. Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease. Neurobiology of Aging. 17: 549-55. PMID 8832629 DOI: 10.1016/S0197-4580(96)00074-7  0.289
1993 Etcheberrigaray R, Ito E, Oka K, Tofel-Grehl B, Gibson GE, Alkon DL. Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 8209-13. PMID 8367484 DOI: 10.1073/Pnas.90.17.8209  0.286
1994 Etcheberrigaray R, Ito E, Kim CS, Alkon DL. Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels. Science (New York, N.Y.). 264: 276-9. PMID 8146663 DOI: 10.1126/Science.8146663  0.284
2014 Takigami S, Sunada H, Lukowiak K, Kuzirian AM, Alkon DL, Sakakibara M. Protein kinase C mediates memory consolidation of taste avoidance conditioning in Lymnaea stagnalis. Neurobiology of Learning and Memory. 111: 9-18. PMID 24613854 DOI: 10.1016/j.nlm.2014.02.011  0.283
1993 Moshiach S, Nelson TJ, Sanchez-Andres JV, Sakakibara M, Alkon DL. G-protein effects on retrograde axonal transport. Brain Research. 605: 298-304. PMID 8481780 DOI: 10.1016/0006-8993(93)91754-G  0.281
1979 Crow T, Heldman E, Hacopian V, Enos R, Alkon DL. Ultrastructure of photoreceptors in the eye of Hermissenda labelled with intracellular injections of horseradish peroxidase. Journal of Neurocytology. 8: 181-95. PMID 469572 DOI: 10.1007/Bf01175560  0.28
1980 Izja Lederhendler I, Barnes ES, Alkon DL. Complex responses to light of the nudibranch Hermissenda crassicornis (Gastropoda: opisthobranchia) Behavioral and Neural Biology. 28: 218-230. DOI: 10.1016/S0163-1047(80)91599-X  0.279
1973 Alkon DL. Neural organization of a molluscan visual system. The Journal of General Physiology. 61: 444-61. PMID 4694742 DOI: 10.1085/Jgp.61.4.444  0.274
1978 Harrigan JF, Alkon DL. Larval rearing, metamorphosis, growth and reproduction of the eolid nudibranch hermissenda crassicornis (eschscholtz, 1831) (gastropoda: opisthobranchia). The Biological Bulletin. 154: 430-9. PMID 20693369 DOI: 10.2307/1541069  0.272
1982 Alkon DL, Lederhendler I, Shoukimas JJ. Primary changes of membrane currents during retention of associative learning. Science (New York, N.Y.). 215: 693-5. PMID 7058334  0.272
2005 Alkon DL, Epstein H, Kuzirian A, Bennett MC, Nelson TJ. Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning. Proceedings of the National Academy of Sciences of the United States of America. 102: 16432-7. PMID 16258064 DOI: 10.1073/pnas.0508001102  0.269
1978 Heldman E, Alkon DL. Neurotransmitter synthesis in the nervous system of the mollusc Hermissenda. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 59: 117-25. PMID 25735 DOI: 10.1016/0306-4492(78)90042-4  0.269
1998 Etcheberrigaray R, Hirashima N, Nee L, Prince J, Govoni S, Racchi M, Tanzi RE, Alkon DL. Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families. Neurobiology of Disease. 5: 37-45. PMID 9702786 DOI: 10.1006/Nbdi.1998.0176  0.269
2004 Pascale A, Gusev PA, Amadio M, Dottorini T, Govoni S, Alkon DL, Quattrone A. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. Proceedings of the National Academy of Sciences of the United States of America. 101: 1217-22. PMID 14745023 DOI: 10.1073/pnas.0307674100  0.267
1975 Adelman W, Alkon DL. Synaptic transmission and neuronal interaction Electroencephalography and Clinical Neurophysiology. 38: 671. DOI: 10.1016/0013-4694(75)90181-9  0.264
1990 Collin C, Papageorge AG, Sakakibara M, Huddie PL, Lowy DR, Alkon DL. Early regulation of membrane excitability by ras oncogene proteins. Biophysical Journal. 58: 785-90. PMID 2207264 DOI: 10.1016/S0006-3495(90)82421-8  0.263
1988 Alkon DL, Rasmussen H. A spatial-temporal model of cell activation. Science (New York, N.Y.). 239: 998-1005. PMID 2830669 DOI: 10.1126/Science.2830669  0.262
1990 Alkon DL, Blackwell KT, Barbour GS, Rigler AK, Vogl TP. Pattern-recognition by an artificial network derived from biologic neuronal systems. Biological Cybernetics. 62: 363-76. PMID 2331490 DOI: 10.1007/Bf00197642  0.261
2008 Sun MK, Hongpaisan J, Nelson TJ, Alkon DL. Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains. Proceedings of the National Academy of Sciences of the United States of America. 105: 13620-5. PMID 18768786 DOI: 10.1073/pnas.0805952105  0.261
1999 Sun MK, Nelson TJ, Xu H, Alkon DL. Calexcitin transformation of GABAergic synapses: from excitation filter to amplifier. Proceedings of the National Academy of Sciences of the United States of America. 96: 7023-8. PMID 10359832 DOI: 10.1073/pnas.96.12.7023  0.259
2002 Sun MK, Xu H, Alkon DL. Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats. The Journal of Pharmacology and Experimental Therapeutics. 300: 408-16. PMID 11805198 DOI: 10.1124/jpet.300.2.408  0.258
1993 Sakakibara M, Takagi H, Yoshioka T, Alkon DL. Propagated calcium modulates the calcium-dependent potassium current by the activation of GABAB receptor at the axonal branch in the type B photoreceptor of Hermissenda. Annals of the New York Academy of Sciences. 707: 492-5. PMID 9137604 DOI: 10.1111/J.1749-6632.1993.Tb38107.X  0.257
2014 Nelson TJ, Alkon DL. Molecular regulation of synaptogenesis during associative learning and memory. Brain Research. PMID 25485772 DOI: 10.1016/j.brainres.2014.11.054  0.257
2013 Hongpaisan J, Xu C, Sen A, Nelson TJ, Alkon DL. PKC activation during training restores mushroom spine synapses and memory in the aged rat. Neurobiology of Disease. 55: 44-62. PMID 23545166 DOI: 10.1016/j.nbd.2013.03.012  0.257
1995 Wang L, Alkon DL. An artificial neural network system for temporal-spatial sequence processing Pattern Recognition. 28: 1267-1276. DOI: 10.1016/0031-3203(94)00181-K  0.256
1998 Meiri N, Sun MK, Segal Z, Alkon DL. Memory and long-term potentiation (LTP) dissociated: normal spatial memory despite CA1 LTP elimination with Kv1.4 antisense. Proceedings of the National Academy of Sciences of the United States of America. 95: 15037-42. PMID 9844011 DOI: 10.1073/Pnas.95.25.15037  0.253
2007 Hongpaisan J, Alkon DL. A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC. Proceedings of the National Academy of Sciences of the United States of America. 104: 19571-6. PMID 18073185 DOI: 10.1073/pnas.0709311104  0.251
2003 Zhao WQ, Chen GH, Chen H, Pascale A, Ravindranath L, Quon MJ, Alkon DL. Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor. The Journal of Biological Chemistry. 278: 4205-15. PMID 12431980 DOI: 10.1074/jbc.M210545200  0.247
1988 Vogl TP, Mangis JK, Rigler AK, Zink WT, Alkon DL. Accelerating the convergence of the back-propagation method Biological Cybernetics. 59: 257-263. DOI: 10.1007/BF00332914  0.244
2010 Sun MK, Alkon DL. Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics. Pharmacology & Therapeutics. 127: 66-77. PMID 20382181 DOI: 10.1016/j.pharmthera.2010.03.001  0.244
1989 Lederhendler II, Alkon DL. The interstimulus interval and classical conditioning in the marine snail Hermissenda crassicornis. Behavioural Brain Research. 35: 75-80. PMID 2803546 DOI: 10.1016/S0166-4328(89)80010-5  0.244
2000 Elbaum D, Brzyska M, Bacia A, Alkon DL. Implication of novel biochemical property of beta-amyloid. Biochemical and Biophysical Research Communications. 267: 733-8. PMID 10673360 DOI: 10.1006/bbrc.1999.2024  0.243
1986 Lederhendler I, Alkon DL. Implicating causal relations between cellular function and learning behavior. Behavioral Neuroscience. 100: 833-8. PMID 3545259 DOI: 10.1037/0735-7044.100.6.833  0.242
2005 Sun MK, Alkon DL. Protein kinase C isozymes: memory therapeutic potential. Current Drug Targets. Cns and Neurological Disorders. 4: 541-52. PMID 16266287 DOI: 10.2174/156800705774322120  0.242
2006 Sun MK, Alkon DL. Protein kinase C pharmacology: perspectives on therapeutic potentials as antidementic and cognitive agents. Recent Patents On Cns Drug Discovery. 1: 147-56. PMID 18221200 DOI: 10.2174/157488906777452721  0.24
1988 Bank B, Nelson T, Alkon DL. Molecular mechanisms of associative learning in mammal and mollusc. Journal De Physiologie. 83: 119-25. PMID 2483171  0.24
1988 Collin C, Ikeno H, Harrigan JF, Lederhendler I, Alkon DL. Sequential modification of membrane currents with classical conditioning. Biophysical Journal. 54: 955-60. PMID 2853980 DOI: 10.1016/S0006-3495(88)83031-5  0.239
2001 Sun M, Dahl D, Alkon DL. Heterosynaptic transformation of GABAergic gating in the hippocampus and effects of carbonic anhydrase inhibition. The Journal of Pharmacology and Experimental Therapeutics. 296: 811-7. PMID 11181911  0.239
2012 Sun MK, Alkon DL. Activation of protein kinase C isozymes for the treatment of dementias. Advances in Pharmacology (San Diego, Calif.). 64: 273-302. PMID 22840750 DOI: 10.1016/B978-0-12-394816-8.00008-8  0.238
2001 Sun MK, Alkon DL. Pharmacological enhancement of synaptic efficacy, spatial learning, and memory through carbonic anhydrase activation in rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 961-7. PMID 11356917  0.238
1991 Sanchez-Andres JV, Alkon DL. Voltage-clamp analysis of the effects of classical conditioning on the hippocampus. Journal of Neurophysiology. 65: 796-807. PMID 2051204  0.235
2005 Gusev PA, Cui C, Alkon DL, Gubin AN. Topography of Arc/Arg3.1 mRNA expression in the dorsal and ventral hippocampus induced by recent and remote spatial memory recall: dissociation of CA3 and CA1 activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9384-97. PMID 16221847 DOI: 10.1523/JNEUROSCI.0832-05.2005  0.234
1981 Grossman Y, Schmidt JA, Alkon DL. Calcium-dependent potassium conductance in the photoresponse of a nudibranch mollusk Comparative Biochemistry and Physiology -- Part a: Physiology. 68: 487-494. DOI: 10.1016/0300-9629(81)90079-7  0.234
1986 Lederhendler II, Gart S, Alkon DL. Classical conditioning of Hermissenda: origin of a new response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1325-31. PMID 3711982  0.232
1980 Alkon DL. Membrane depolarization accumulates during acquisition of an associative behavioral change. Science (New York, N.Y.). 210: 1375-6. PMID 7434034  0.231
2004 Amadio M, Govoni S, Alkon DL, Pascale A. Emerging targets for the pharmacology of learning and memory. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 50: 111-22. PMID 15177298 DOI: 10.1016/j.phrs.2004.01.003  0.23
1985 Goh Y, Lederhendler I, Alkon DL. Input and output changes of an identified neural pathway are correlated with associative learning in Hermissenda. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 536-43. PMID 3973682  0.229
1984 Connor J, Alkon DL. Light- and voltage-dependent increases of calcium ion concentration in molluscan photoreceptors. Journal of Neurophysiology. 51: 745-52. PMID 6716122  0.227
2001 Quattrone A, Pascale A, Nogues X, Zhao W, Gusev P, Pacini A, Alkon DL. Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 11668-73. PMID 11573004 DOI: 10.1073/pnas.191388398  0.227
1993 Alkon DL, Etcheberrigaray R, Rojas E. Distribution of voltage sensors in mammalian outer hair cells. Biophysical Journal. 65: 1755-6. PMID 8298008 DOI: 10.1016/S0006-3495(93)81232-3  0.226
1996 Dettmar HP, Barbour GS, Blackwell KT, Vogl TP, Alkon DL, Fry FS, Totah JE, Chambers TL. Orange juice classification with a biologically based neural network. Computers & Chemistry. 20: 261-6. PMID 8936424 DOI: 10.1016/0097-8485(95)00015-1  0.225
1980 Akaike T, Alkon DL. Sensory convergence on central visual neurons in Hermissenda. Journal of Neurophysiology. 44: 501-13. PMID 6969298 DOI: 10.1152/Jn.1980.44.3.501  0.224
1984 Goh Y, Alkon DL. Sensory, interneuronal, and motor interactions within Hermissenda visual pathway. Journal of Neurophysiology. 52: 156-69. PMID 6086855  0.223
1983 Neary JT, Alkon DL. Protein phosphorylation/dephosphorylation and the transient, voltage-dependent potassium conductance in Hermissenda crassicornis. The Journal of Biological Chemistry. 258: 8979-83. PMID 6306008  0.222
1978 Alkon DL, Grossman Y. Evidence for nonsynaptic neuronal interaction. Journal of Neurophysiology. 41: 640-53. PMID 207829  0.222
2000 Sun MK, Nelson TJ, Alkon DL. Functional switching of GABAergic synapses by ryanodine receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 97: 12300-5. PMID 11027306 DOI: 10.1073/pnas.210396697  0.221
1989 Nelson TJ, Alkon DL. Specific protein changes during memory acquisition and storage. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 10: 75-9. PMID 2541697 DOI: 10.1002/bies.950100209  0.22
1997 Blackwell KT, Vogl TP, Dettmar HP, Brown MA, Barbour GS, Alkon DL. Identification of faces obscured by noise: Comparison of an artificial neural network with human observers Journal of Experimental and Theoretical Artificial Intelligence. 9: 491-508. DOI: 10.1080/095281397147004  0.22
2016 Sen A, Hongpaisan J, Wang D, Nelson TJ, Alkon DL. PKC epsilon Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95. The Journal of Biological Chemistry. PMID 27330081 DOI: 10.1074/jbc.M116.730440  0.217
2000 Alkon DL. Quantum basis for the relativistic Doppler effect for light Inzhenerno-Fizicheskii Zhurnal. 73: 860-870. DOI: 10.1007/S10891-000-0103-8  0.217
2005 Dou JT, Chen M, Dufour F, Alkon DL, Zhao WQ. Insulin receptor signaling in long-term memory consolidation following spatial learning. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 646-55. PMID 16287721 DOI: 10.1101/lm.88005  0.216
2006 Tan DP, Liu QY, Koshiya N, Gu H, Alkon D. Enhancement of long-term memory retention and short-term synaptic plasticity in cbl-b null mice Proceedings of the National Academy of Sciences of the United States of America. 103: 5125-5130. PMID 16549761 DOI: 10.1073/pnas.0601043103  0.216
1994 Alkon DL, Blackwell KT, Barbour GS, Werness SA, Vogl TP. Biological plausibility of synaptic associative memory models Neural Networks. 7: 1005-1017. DOI: 10.1016/S0893-6080(05)80156-X  0.214
2009 Sun MK, Alkon DL. Protein kinase C activators as synaptogenic and memory therapeutics. Archiv Der Pharmazie. 342: 689-98. PMID 19899099 DOI: 10.1002/ardp.200900050  0.213
2012 Lim CS, Alkon DL. Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture. Hippocampus. 22: 2303-19. PMID 22736542 DOI: 10.1002/hipo.22048  0.208
2005 Pascale A, Amadio M, Scapagnini G, Lanni C, Racchi M, Provenzani A, Govoni S, Alkon DL, Quattrone A. Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 12065-70. PMID 16099831 DOI: 10.1073/pnas.0504702102  0.207
1991 Lester DS, Collin C, Etcheberrigaray R, Alkon DL. Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo. Biochemical and Biophysical Research Communications. 179: 1522-8. PMID 1930192 DOI: 10.1016/0006-291X(91)91745-X  0.206
2014 Sun MK, Alkon DL. The "memory kinases": roles of PKC isoforms in signal processing and memory formation. Progress in Molecular Biology and Translational Science. 122: 31-59. PMID 24484697 DOI: 10.1016/B978-0-12-420170-5.00002-7  0.205
1994 Nelson TJ, Yoshioka T, Toyoshima S, Han YF, Alkon DL. Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport. Proceedings of the National Academy of Sciences of the United States of America. 91: 9287-91. PMID 7937757 DOI: 10.1073/Pnas.91.20.9287  0.205
2017 Lim CS, Alkon DL. Inhibition of Coactivator-associated Arginine Methyltransferase 1 Modulates Dendritic Arborization and Spine Maturation of Cultured Hippocampal Neurons. The Journal of Biological Chemistry. PMID 28264928 DOI: 10.1074/jbc.M117.775619  0.205
2008 Sun MK, Alkon DL. Synergistic effects of chronic bryostatin-1 and alpha-tocopherol on spatial learning and memory in rats. European Journal of Pharmacology. 584: 328-37. PMID 18313045 DOI: 10.1016/j.ejphar.2008.02.014  0.205
2014 Sun MK, Hongpaisan J, Lim CS, Alkon DL. Bryostatin-1 restores hippocampal synapses and spatial learning and memory in adult fragile x mice. The Journal of Pharmacology and Experimental Therapeutics. 349: 393-401. PMID 24659806 DOI: 10.1124/jpet.114.214098  0.204
2009 Sun MK, Hongpaisan J, Alkon DL. Postischemic PKC activation rescues retrograde and anterograde long-term memory. Proceedings of the National Academy of Sciences of the United States of America. 106: 14676-80. PMID 19667190 DOI: 10.1073/pnas.0907842106  0.203
1990 Lederhendler II, Collin C, Alkon DL. Sequential changes of potassium currents in Hermissenda type B photoreceptor during early stages of classical conditioning. Neuroscience Letters. 110: 28-33. PMID 2325887 DOI: 10.1016/0304-3940(90)90782-5  0.202
1982 Alkon DL, Shoukimas JJ, Heldman E. Calcium-mediated decrease of a voltage-dependent potassium current. Biophysical Journal. 40: 245-50. PMID 7183338 DOI: 10.1016/S0006-3495(82)84479-2  0.201
2004 Sun MK, Alkon DL. Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats. Journal of Alzheimer's Disease : Jad. 6: 355-66; discussion 4. PMID 15345805  0.2
2005 Sun MK, Alkon DL. Dual effects of bryostatin-1 on spatial memory and depression. European Journal of Pharmacology. 512: 43-51. PMID 15814089 DOI: 10.1016/j.ejphar.2005.02.028  0.199
2004 Nelson TJ, Backlund PS, Alkon DL. Hippocampal protein-protein interactions in spatial memory. Hippocampus. 14: 46-57. PMID 15058482 DOI: 10.1002/hipo.10152  0.198
2002 Sun MK, Alkon DL. Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35). Journal of Neurophysiology. 87: 2441-9. PMID 11976381 DOI: 10.1152/jn.00230.2001  0.197
2009 Nelson TJ, Alkon DL. Neuroprotective versus tumorigenic protein kinase C activators. Trends in Biochemical Sciences. 34: 136-45. PMID 19233655 DOI: 10.1016/j.tibs.2008.11.006  0.197
1991 Werness SA, Fay SD, Vogl TP, Blackwell KT, Alkon DL. A model of associative learning in Hermissenda crassicornis: Sensitivities to temporal relationships of stimuli Proceedings of the Annual Conference On Engineering in Medicine and Biology. 13: 1423-1424.  0.196
1979 Heldman E, Grossman Y, Jerussi TP, Alkon DL. Cholinergic features of photoreceptor synapses in Hermissenda. Journal of Neurophysiology. 42: 153-65. PMID 34673  0.195
2006 Sun MK, Alkon DL. Bryostatin-1: pharmacology and therapeutic potential as a CNS drug. Cns Drug Reviews. 12: 1-8. PMID 16834754 DOI: 10.1111/j.1527-3458.2006.00001.x  0.194
2020 Cogram P, Alkon DL, Crockford D, Deacon RMJ, Hurley MJ, Altimiras F, Sun MK, Tranfaglia M. Chronic bryostatin-1 rescues autistic and cognitive phenotypes in the fragile X mice. Scientific Reports. 10: 18058. PMID 33093534 DOI: 10.1038/s41598-020-74848-6  0.192
2002 Cavallaro S, D'Agata V, Manickam P, Dufour F, Alkon DL. Memory-specific temporal profiles of gene expression in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 99: 16279-84. PMID 12461180 DOI: 10.1073/pnas.242597199  0.191
2014 Lim CS, Alkon DL. PKCε promotes HuD-mediated neprilysin mRNA stability and enhances neprilysin-induced Aβ degradation in brain neurons. Plos One. 9: e97756. PMID 24848988 DOI: 10.1371/journal.pone.0097756  0.191
1990 Nelson TJ, Alkon DL. Specific high molecular weight mRNAs induced by associative learning in Hermissenda. Proceedings of the National Academy of Sciences of the United States of America. 87: 269-73. PMID 2296586 DOI: 10.1073/pnas.87.1.269  0.191
2012 Sen A, Alkon DL, Nelson TJ. Apolipoprotein E3 (ApoE3) but not ApoE4 protects against synaptic loss through increased expression of protein kinase C epsilon. The Journal of Biological Chemistry. 287: 15947-58. PMID 22427674 DOI: 10.1074/jbc.M111.312710  0.191
1987 Alkon DL, Bank B, Naito S, Chen C, Ram J. Inhibition of protein synthesis prolongs Ca2+-mediated reduction of K+ currents in molluscan neurons. Proceedings of the National Academy of Sciences of the United States of America. 84: 6948-52. PMID 3477819  0.19
1994 Huang HM, Martins R, Gandy S, Etcheberrigaray R, Ito E, Alkon DL, Blass J, Gibson G. Use of cultured fibroblasts in elucidating the pathophysiology and diagnosis of Alzheimer's disease. Annals of the New York Academy of Sciences. 747: 225-44. PMID 7847673 DOI: 10.1111/J.1749-6632.1994.Tb44412.X  0.189
1995 Alkon DL. Molecular mechanisms of associative memory and their clinical implications. Behavioural Brain Research. 66: 151-60. PMID 7538770 DOI: 10.1016/0166-4328(94)00142-3  0.189
2008 Nelson TJ, Sun MK, Hongpaisan J, Alkon DL. Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair. European Journal of Pharmacology. 585: 76-87. PMID 18402935 DOI: 10.1016/j.ejphar.2008.01.051  0.189
1993 Höpp HP, Alkon DL. Different ionic conductances are modulated during the late receptor potential and the prolonged depolarizing afterpotential in Hermissenda type A photoreceptors. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 172: 47-55. PMID 8445579 DOI: 10.1007/BF00214714  0.187
2003 Epstein HT, Child FM, Kuzirian AM, Alkon DL. Time windows for effects of protein synthesis inhibitors on Pavlovian conditioning in Hermissenda: behavioral aspects. Neurobiology of Learning and Memory. 79: 127-31. PMID 12591220 DOI: 10.1016/S1074-7427(02)00020-5  0.187
2003 Zhao WQ, Feng C, Alkon DL. Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts. Neurobiology of Disease. 14: 458-69. PMID 14678762 DOI: 10.1016/S0969-9961(03)00124-4  0.187
1989 Alkon DL, Eldred K. The nature of memory. Endeavour. 13: 29-33. PMID 2467804  0.184
1994 Sakakibara M, Alkon DL, Kouchi T, Inoue H, Yoshioka T. Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor. Biochemical and Biophysical Research Communications. 202: 299-306. PMID 7518677 DOI: 10.1006/Bbrc.1994.1927  0.183
1996 Schachter JB, Lester DS, Alkon DL. Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity. Biochimica Et Biophysica Acta. 1291: 167-76. PMID 8898879 DOI: 10.1016/0304-4165(96)00063-3  0.183
1980 Crow TJ, Alkon DL. Associative behavioral modification in hermissenda: cellular correlates. Science (New York, N.Y.). 209: 412-4. PMID 17747814 DOI: 10.1126/science.209.4454.412  0.183
1980 Stommel EW, Stephens RE, Alkon DL. Motile statocyst cilia transmit rather than directly transduce mechanical stimuli. The Journal of Cell Biology. 87: 652-62. PMID 7462319  0.18
2006 Dufour F, Liu QY, Gusev P, Alkon D, Atzori M. Cholesterol-enriched diet affects spatial learning and synaptic function in hippocampal synapses. Brain Research. 1103: 88-98. PMID 16814755 DOI: 10.1016/j.brainres.2006.05.086  0.179
2005 Nelson TJ, Alkon DL. Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. Biochemical Society Transactions. 33: 1033-6. PMID 16246039 DOI: 10.1042/BST20051033  0.178
1988 Nelson TJ, Alkon DL. Prolonged RNA changes in the Hermissenda eye induced by classical conditioning. Proceedings of the National Academy of Sciences of the United States of America. 85: 7800-4. PMID 3174664  0.178
1982 West A, Barnes E, Alkon DL. Primary changes of voltage responses during retention of associative learning. Journal of Neurophysiology. 48: 1243-55. PMID 6816909  0.177
2009 Xu C, Cui C, Alkon DL. Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors. Hippocampus. 19: 706-17. PMID 19123252 DOI: 10.1002/hipo.20544  0.175
1992 Blackwell KT, Vogl TP, Hyman SD, Barbour GS, Alkon DL. A new approach to hand-written character recognition Pattern Recognition. 25: 655-666. DOI: 10.1016/0031-3203(92)90082-T  0.174
1983 Alkon DL. The role of statocyst sensory cilia in mechanotransduction Journal of Submicroscopic Cytology. 15: 145-150.  0.174
2003 Nelson TJ, Quattrone A, Kim J, Pacini A, Cesati V, Alkon DL. Calcium-regulated GTPase activity in the calcium-binding protein calexcitin. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 135: 627-38. PMID 12892754 DOI: 10.1016/S1096-4959(03)00144-1  0.173
2001 Grimaldi M, Atzori M, Ray P, Alkon DL. Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3135-43. PMID 11312298 DOI: 10.1523/Jneurosci.21-09-03135.2001  0.172
1991 Alkon DL, Amaral DG, Bear MF, Black J, Carew TJ, Cohen NJ, Disterhoft JF, Eichenbaum H, Golski S, Gorman LK. Learning and memory. FESN Study Group. Brain Research. Brain Research Reviews. 16: 193-220. PMID 1760656 DOI: 10.1016/0165-0173(91)90005-S  0.171
2008 Sun MK, Alkon DL. Effects of 4-methylcatechol on spatial memory and depression. Neuroreport. 19: 355-9. PMID 18303581 DOI: 10.1097/WNR.0b013e3282f519c7  0.171
2004 Ma W, Fitzgerald W, Liu QY, O'Shaughnessy TJ, Maric D, Lin HJ, Alkon DL, Barker JL. CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels. Experimental Neurology. 190: 276-88. PMID 15530869 DOI: 10.1016/j.expneurol.2003.10.016  0.169
2023 La Cognata V, D'Amico AG, Maugeri G, Morello G, Guarnaccia M, Magrì B, Aronica E, Alkon DL, D'Agata V, Cavallaro S. The ε-Isozyme of Protein Kinase C (PKCε) Is Impaired in ALS Motor Cortex and Its Pulse Activation by Bryostatin-1 Produces Long Term Survival in Degenerating SOD1-G93A Motor Neuron-like Cells. International Journal of Molecular Sciences. 24. PMID 37629005 DOI: 10.3390/ijms241612825  0.169
2004 Sun MK, Alkon DL. Induced depressive behavior impairs learning and memory in rats. Neuroscience. 129: 129-39. PMID 15489036 DOI: 10.1016/j.neuroscience.2004.07.041  0.168
1988 Usui S, Ikeno H, Sakakibara M, Alkon DL. Neural principles of associative learning: Reconstruction of ionic currents in the type B photoreceptor Neural Networks. 1: 280. DOI: 10.1016/0893-6080(88)90314-0  0.168
1991 Miyazawa A, Inoue H, Yoshioka T, Alkon DL. A direct evidence that protein kinase C exists in the neuron of Neuroscience Research Supplements. 16: 155. DOI: 10.1016/0921-8696(91)91099-E  0.167
2001 Zhao WQ, Alkon DL. Role of insulin and insulin receptor in learning and memory. Molecular and Cellular Endocrinology. 177: 125-34. PMID 11377828 DOI: 10.1016/S0303-7207(01)00455-5  0.166
1985 Alkon DL, Sakakibara M. Calcium activates and inactivates a photoreceptor soma potassium current. Biophysical Journal. 48: 983-95. PMID 4092073 DOI: 10.1016/S0006-3495(85)83861-3  0.163
2007 Alkon DL, Sun MK, Nelson TJ. PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease. Trends in Pharmacological Sciences. 28: 51-60. PMID 17218018 DOI: 10.1016/j.tips.2006.12.002  0.162
1991 Takagi H, Yoshioka T, Sakakibara M, Collin C, Alkon DL. Whole cell clamp study of gabaergic responses of type B photoreceptors in Neuroscience Research Supplements. 16: 155. DOI: 10.1016/0921-8696(91)91100-7  0.161
2009 Nelson TJ, Cui C, Luo Y, Alkon DL. Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators. The Journal of Biological Chemistry. 284: 34514-21. PMID 19850930 DOI: 10.1074/jbc.M109.016683  0.161
2004 Etcheberrigaray R, Tan M, Dewachter I, Kuipéri C, Van der Auwera I, Wera S, Qiao L, Bank B, Nelson TJ, Kozikowski AP, Van Leuven F, Alkon DL. Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 11141-6. PMID 15263077 DOI: 10.1073/pnas.0403921101  0.161
2005 Sun MK, Alkon DL. Protein kinase C substrate activators: Potential as novel antidepressants Drug Development Research. 65: 156-169. DOI: 10.1002/ddr.20019  0.161
1995 Collin C, Devane WA, Dahl D, Lee CJ, Axelrod J, Alkon DL. Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. Proceedings of the National Academy of Sciences of the United States of America. 92: 10167-71. PMID 7479747 DOI: 10.1073/pnas.92.22.10167  0.158
2003 Scapagnini G, Nelson TJ, Alkon DL. Regulation of Ca2+ stores in glial cells Advances in Molecular and Cell Biology. 31: 635-660. DOI: 10.1016/S1569-2558(03)31029-X  0.158
2016 Sun MK, Hongpaisan J, Alkon DL. Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26941170 DOI: 10.1124/jpet.115.231100  0.157
2002 Nelson TJ, Etcheberrigaray R, Alkon DL. Calcium-dependent cascades in physiological and pathological memory processes Pharmaceutical News. 9: 473-478.  0.155
1993 Sakakibara M, Ikeno H, Usui S, Collin C, Alkon DL. Reconstruction of ionic currents in a molluscan photoreceptor. Biophysical Journal. 65: 519-27. PMID 8369456 DOI: 10.1016/S0006-3495(93)81068-3  0.155
2004 Amadio M, Quattrone A, Alkon DL, Racchi M, Govoni S, Pascale A. P2-124 PKC and ELAV-like mRNA binding proteins: a new cascade for memory trace formation and Alzheimer's disease Neurobiology of Aging. 25: S260. DOI: 10.1016/S0197-4580(04)80871-6  0.154
1998 Favit A, Grimaldi M, Nelson TJ, Alkon DL. Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 95: 5562-7. PMID 9576922  0.152
1977 DeFelice LJ, Alkon DL. Voltage noise from hair cells during mechanical stimulation. Nature. 269: 613-5. PMID 917109 DOI: 10.1038/269613a0  0.151
1981 Kuzirian AM, Alkon DL, Harris LG. An infraciliary network in statocyst hair cells. Journal of Neurocytology. 10: 497-514. PMID 7310462 DOI: 10.1007/BF01262418  0.151
2011 Hongpaisan J, Sun MK, Alkon DL. PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 630-43. PMID 21228172 DOI: 10.1523/JNEUROSCI.5209-10.2011  0.15
2002 Sun MK, Alkon DL. Carbonic anhydrase gating of attention: memory therapy and enhancement. Trends in Pharmacological Sciences. 23: 83-9. PMID 11830265 DOI: 10.1016/S0165-6147(02)01899-0  0.149
2003 Dou J, Cui C, Dufour F, Alkon DL, Zhao WQ. Gene expression of alpha-endosulfine in the rat brain: correlative changes with aging, learning and stress. Journal of Neurochemistry. 87: 1086-100. PMID 14622089 DOI: 10.1046/j.1471-4159.2003.02094.x  0.148
2015 Sun MK, Nelson TJ, Alkon DL. Towards universal therapeutics for memory disorders. Trends in Pharmacological Sciences. 36: 384-394. PMID 25959522 DOI: 10.1016/j.tips.2015.04.004  0.148
2002 Sun MK, Alkon DL. Depressed or demented: common CNS drug targets?! Current Drug Targets. Cns and Neurological Disorders. 1: 575-92. PMID 12769599  0.143
2004 Epstein HT, Kuzirian AM, Child FM, Alkon DL. Two different biological configurations for long-term memory. Neurobiology of Learning and Memory. 81: 12-8. PMID 14670354 DOI: 10.1016/S1074-7427(03)00074-1  0.142
2011 Zohar O, Lavy R, Zi X, Nelson TJ, Hongpaisan J, Pick CG, Alkon DL. PKC activator therapeutic for mild traumatic brain injury in mice. Neurobiology of Disease. 41: 329-37. PMID 20951803 DOI: 10.1016/j.nbd.2010.10.001  0.14
1990 Collin C, Papageorge AG, Lowy DR, Alkon DL. Early enhancement of calcium currents by H-ras oncoproteins injected into Hermissenda neurons. Science (New York, N.Y.). 250: 1743-5. PMID 2176747  0.135
2002 Cavallaro S, Dagata V, Alkon DL. Programs of gene expression during the laying down of memory formation as revealed by DNA microarrays. Neurochemical Research. 27: 1201-7. PMID 12462418 DOI: 10.1023/A:1020933627597  0.134
2017 Alkon DL, Hongpaisan J, Sun MK. Effects of chronic bryostatin-1 on treatment-resistant depression in rats. European Journal of Pharmacology. PMID 28472666 DOI: 10.1016/j.ejphar.2017.05.001  0.134
2002 Nelson TJ, Backlund PS, Yergey AL, Alkon DL. Isolation of protein subpopulations undergoing protein-protein interactions. Molecular & Cellular Proteomics : McP. 1: 253-9. PMID 12096125  0.134
1975 Alkon DL. A dual synaptic effect on hair cells in Hermissenda. The Journal of General Physiology. 65: 385-97. PMID 163891  0.131
2014 Sun MK, Alkon DL. Protein kinase c isoform activity and cognitive functions Advances in Cognitive and Behavioral Sciences. 43-78.  0.13
2009 Khan TK, Nelson TJ, Verma VA, Wender PA, Alkon DL. A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Abeta-induced biomarker abnormality on cultured fibroblasts. Neurobiology of Disease. 34: 332-9. PMID 19233276 DOI: 10.1016/J.Nbd.2009.02.003  0.13
1998 Zohar O, Ikeda M, Shinagawa H, Inoue H, Nakamura H, Elbaum D, Alkon DL, Yoshioka T. Thermal imaging of receptor-activated heat production in single cells. Biophysical Journal. 74: 82-9. PMID 9449312 DOI: 10.1016/S0006-3495(98)77769-0  0.129
2015 Lucke-Wold BP, Turner RC, Logsdon AF, Simpkins JW, Alkon DL, Smith KE, Chen YW, Tan Z, Huber JD, Rosen CL. Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration. Journal of Alzheimer's Disease : Jad. 43: 711-24. PMID 25114088 DOI: 10.3233/Jad-141422  0.129
1998 Kuzirian AM, Epstein HT, Nelson TJ, Rafferty NS, Alkon DL. Lead, learning, and calexcitin in Hermissenda. The Biological Bulletin. 195: 198-201. PMID 9818368 DOI: 10.2307/1542837  0.129
2004 Scioletti AB, Kuzirian AM, Epstein HT, Nelson TJ, Alkon DL. Memory Enhancement by Bryostatin in Hermissenda. The Biological Bulletin. 207: 159. PMID 27690570 DOI: 10.1086/BBLv207n2p159  0.127
1983 Alkon DL. Learning in a marine snail. Scientific American. 249: 70-4, 76-8, 80-4. PMID 6879141  0.127
1991 Collin C, Ito E, Sakakibara M, Kudo Y, Alkon DL, Yoshioka T. GABA-induced calcium elevation in the terminal branches of type B photoreceptors Neuroscience Research Supplements. 16: 154. DOI: 10.1016/0921-8696(91)91098-D  0.126
1989 Nelson TJ, Alkon DL. Protein changes underlying long-term facilitation in Aplysia. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 11: 106-8. PMID 2695076 DOI: 10.1002/bies.950110407  0.126
2000 Favit A, Grimaldi M, Alkon DL. Prevention of beta-amyloid neurotoxicity by blockade of the ubiquitin-proteasome proteolytic pathway. Journal of Neurochemistry. 75: 1258-63. PMID 10936209 DOI: 10.1046/j.1471-4159.2000.0751258.x  0.124
1990 Alkon DL. Biophysics of memory. Progress in Clinical and Biological Research. 334: 273-7. PMID 2309007  0.124
2005 Sun M, Alkon DL. Corrigendum to “Dual effects of bryostatin-1 on spatial memory and depression” [Eur. J. Pharmacol. 512 (2005) 43–51] European Journal of Pharmacology. 525: 171. DOI: 10.1016/J.EJPHAR.2005.10.003  0.124
1992 Collin C, Alkon DL. Neural correlates of memory storage. The role of ion channels. Ion Channels. 3: 159-75. PMID 1384757 DOI: 10.1007/978-1-4615-3328-3_6  0.123
1989 Alkon DL. Memory storage and neural systems. Scientific American. 261: 42-50. PMID 2473528  0.123
1982 Senft SL, Allen RD, Crow T, Alkon DL. Optical sectioning of HRP-stained molluscan neurons. Journal of Neuroscience Methods. 5: 153-9. PMID 7035759 DOI: 10.1016/0165-0270(82)90062-0  0.123
1993 Werness SA, Fay SD, Blackwell KT, Vogl TP, Alkon DL. Associative learning in a network model of Hermissenda crassicornis - II. Experiments Biological Cybernetics. 70: 95. DOI: 10.1007/BF00202571  0.121
2018 Sen A, Nelson TJ, Alkon DL, Hongpaisan J. Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's Disease : Jad. PMID 29710707 DOI: 10.3233/JAD-171008  0.121
2003 Child FM, Epstein HT, Kuzirian AM, Alkon DL. Memory reconsolidation in Hermissenda. The Biological Bulletin. 205: 218-9. PMID 14583538 DOI: 10.2307/1543261  0.12
2024 Sun MK, Alkon DL. Alzheimer's therapeutic development: shifting neurodegeneration to neuroregeneration. Trends in Pharmacological Sciences. 45: 197-209. PMID 38360510 DOI: 10.1016/j.tips.2024.01.012  0.12
1989 Sakakibara M, Usui S, Alkon DL. Role of phospholipid metabolic products in associative learning Neuroscience Research Supplements. 9: 11. DOI: 10.1016/0921-8696(89)90515-X  0.118
2000 Park S, Nelson TJ, Alkon DL, Kim J. Functional Characterization of the Squid Calexcitin-2, a Calcium and GTP-binding Protein Journal of Biochemistry and Molecular Biology. 33: 391-395.  0.117
2014 Lucke-Wold BP, Logsdon AF, Smith KE, Turner RC, Alkon DL, Tan Z, Naser ZJ, Knotts CM, Huber JD, Rosen CL. Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury. Molecular Neurobiology. PMID 25301233 DOI: 10.1007/S12035-014-8902-7  0.116
1999 Alkon DL. Molecular principles of associative memory that are conserved during the evolution of species Malacologia. 41: 321-329.  0.115
2017 Nelson TJ, Sun MK, Lim C, Sen A, Khan T, Chirila FV, Alkon DL. Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer's Disease Phase IIa and Expanded Access Trials. Journal of Alzheimer's Disease : Jad. PMID 28482641 DOI: 10.3233/Jad-170161  0.114
2004 Cavallaro S, D'Agata V, Alessi E, Coffa S, Alkon DL, Manickam P, Ciotti MT, Possenti R, Bonini P, Marlier L, Calissano P. Gene expression profiles of apoptotic neurons. Genomics. 84: 485-96. PMID 15498456 DOI: 10.1016/j.ygeno.2004.04.006  0.114
2002 D'Agata V, Warren ST, Zhao W, Torre ER, Alkon DL, Cavallaro S. Gene expression profiles in a transgenic animal model of fragile X syndrome. Neurobiology of Disease. 10: 211-8. PMID 12270684 DOI: 10.1006/Nbdi.2002.0506  0.114
1993 Etcheberrigaray R, Ito E, Oka K, Tofel-Grehl B, Gibson GE, Alkon DL. New implications of memory mechanisms for Alzheimer's disease Neuroscience Research Communications. 12: S7-S10.  0.112
1979 Grossman Y, Alkon DL, Heldman E. A common origin of voltage noise and generator potentials in statocyst hair cells. The Journal of General Physiology. 73: 23-48. PMID 438764  0.11
2015 Sen A, Nelson TJ, Alkon DL. ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7538-51. PMID 25972179 DOI: 10.1523/JNEUROSCI.0260-15.2015  0.108
2019 Sun MK, Alkon DL. Neuro-regeneration Therapeutic for Alzheimer's Dementia: Perspectives on Neurotrophic Activity. Trends in Pharmacological Sciences. 40: 655-668. PMID 31402121 DOI: 10.1016/j.tips.2019.07.008  0.107
2013 Tan Z, Turner RC, Leon RL, Li X, Hongpaisan J, Zheng W, Logsdon AF, Naser ZJ, Alkon DL, Rosen CL, Huber JD. Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke. Stroke; a Journal of Cerebral Circulation. 44: 3490-7. PMID 24172582 DOI: 10.1161/Strokeaha.113.002411  0.106
1993 Ito E, Etcheberrigaray R, Oka K, Tofelgrehl B, Gibson GE, Alkon DL. 615 A laboratory diagnosis of alzheimer's disease with patch-clamp and CA2+-imaging techniques Neuroscience Research Supplements. 18: S76. DOI: 10.1016/S0921-8696(05)80883-7  0.106
1981 Jerussi TP, Alkon DL. Ocular and extraocular responses of identifiable neurons in pedal ganglia of Hermissenda crassicornis. Journal of Neurophysiology. 46: 659-71. PMID 7299440  0.105
1991 Etcheberrigaray R, Huddie PL, Alkon DL. Gigaohm single-channel recording from isolated Hermissenda crassicornis type B photoreceptors. The Journal of Experimental Biology. 156: 619-23. PMID 2051138  0.105
2000 Etcheberrigaray R, Bhagavan S, Bank B, Alkon DL. Calcium responses are altered in fibroblasts from Alzheimer's patients and pre-symptomatic PS1 carriers: A potential tool for early diagnosis Alzheimer's Reports. 3: 305-312.  0.104
2000 Zhang L, Zhao W, Li B, Alkon DL, Barker JL, Chang YH, Wu M, Rubinow DR. TNF-alpha induced over-expression of GFAP is associated with MAPKs. Neuroreport. 11: 409-12. PMID 10674496 DOI: 10.1097/00001756-200002070-00037  0.103
2005 Nelson TJ, Alkon DL. Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. The Journal of Biological Chemistry. 280: 7377-87. PMID 15591071 DOI: 10.1074/jbc.M409071200  0.101
2007 Nelson TJ, Alkon DL. Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid. The Journal of Biological Chemistry. 282: 31238-49. PMID 17761669 DOI: 10.1074/jbc.M705558200  0.101
2005 Zohar O, Pick CG, Cavallaro S, Chapman J, Katzav A, Milman A, Alkon DL. Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice. Neurobiology of Aging. 26: 1167-75. PMID 15917100 DOI: 10.1016/j.neurobiolaging.2004.10.005  0.101
2001 Alkon DL. "Either-or" two-slit interference: stable coherent propagation of individual photons through separate slits. Biophysical Journal. 80: 2056-61. PMID 11325709 DOI: 10.1016/S0006-3495(01)76179-6  0.101
2006 Khan TK, Alkon DL. An internally controlled peripheral biomarker for Alzheimer's disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin. Proceedings of the National Academy of Sciences of the United States of America. 103: 13203-7. PMID 16920798 DOI: 10.1073/pnas.0605411103  0.099
1998 Nelson TJ, Gusev PA, Alkon DL. Identification of ion channel regulating proteins by patch-clamp analysis. Methods in Enzymology. 293: 194-201. PMID 9711610 DOI: 10.1016/S0076-6879(98)93015-4  0.098
2002 Scapagnini G, D'Agata V, Calabrese V, Pascale A, Colombrita C, Alkon D, Cavallaro S. Gene expression profiles of heme oxygenase isoforms in the rat brain Brain Research. 954: 51-59. PMID 12393232 DOI: 10.1016/S0006-8993(02)03338-3  0.096
2004 Zhao WQ, Chen H, Quon MJ, Alkon DL. Insulin and the insulin receptor in experimental models of learning and memory. European Journal of Pharmacology. 490: 71-81. PMID 15094074 DOI: 10.1016/j.ejphar.2004.02.045  0.095
2017 Khan TK, Wender PA, Alkon DL. Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents. Journal of Cellular Physiology. PMID 28590053 DOI: 10.1002/Jcp.26043  0.095
2000 Etcheberrigaray R, Bhagavan S, Bank B, Alkon DL. Tea- and bradykinin(BK)-induced calcium responses in Alzheimer's disease (AD) and control fibroblasts: A ratio index with diagnostic capability Neurobiology of Aging. 21: 12. DOI: 10.1016/S0197-4580(00)82732-3  0.093
1994 Ito E, Etcheberrigaray R, Alkon DL. Alzheimer's phenotype K+ channel dysfunction in human skin fibroblasts caused by β-amyloid protein Neuroscience Research Supplements. 19: S155. DOI: 10.1016/0921-8696(94)92703-0  0.093
2015 Khan TK, Sen A, Hongpaisan J, Lim CS, Nelson TJ, Alkon DL. PKCε deficits in Alzheimer's disease brains and skin fibroblasts. Journal of Alzheimer's Disease : Jad. 43: 491-509. PMID 25125477 DOI: 10.3233/JAD-141221  0.093
2022 Thompson RE, Tuchman AJ, Alkon DL. Bryostatin Placebo-Controlled Trials Indicate Cognitive Restoration Above Baseline for Advanced Alzheimer's Disease in the Absence of Memantine1. Journal of Alzheimer's Disease : Jad. PMID 35124654 DOI: 10.3233/JAD-215545  0.092
2003 Zohar O, Cavallaro S, D'Agata V, Alkon DL. Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain. Brain Research. Molecular Brain Research. 115: 63-8. PMID 12824056 DOI: 10.1016/S0169-328X(03)00182-7  0.092
2013 Sun MK, Alkon DL. Cerebral ischemia-induced difference in sensitivity to depression and potential therapeutics in rats. Behavioural Pharmacology. 24: 222-8. PMID 23591125 DOI: 10.1097/FBP.0b013e3283618afe  0.091
2003 Colombrita C, Calabrese V, Stella AM, Mattei F, Alkon DL, Scapagnini G. Regional rat brain distribution of heme oxygenase-1 and manganese superoxide dismutase mRNA: relevance of redox homeostasis in the aging processes. Experimental Biology and Medicine (Maywood, N.J.). 228: 517-24. PMID 12709579  0.09
1987 Sakakibara M, Ikeno H, Alkon DL, Usui S, Watanabe S. Ionic current model on the type B photoreceptor in hermissenda Neuroscience Research Supplements. 5: S189. DOI: 10.1016/0921-8696(87)90387-2  0.089
1995 Wolozin B, Hirashima N, Luo Y, Li YH, Alkon DL, Etcheberrigaray R, Sunderland T. Transforming growth factor beta induces a beta-responsive calcium fluxes in neurons. Neuroreport. 6: 1429-33. PMID 7488741  0.089
2002 Scapagnini G, Ravagna A, Bella R, Colombrita C, Pennisi G, Calvani M, Alkon D, Calabrese V. Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: Protection by acetyl carnitine International Journal of Tissue Reactions. 24: 89-96. PMID 12635861  0.087
2006 Sun MK, Alkon DL. Differential gender-related vulnerability to depression induction and converging antidepressant responses in rats. The Journal of Pharmacology and Experimental Therapeutics. 316: 926-32. PMID 16227471 DOI: 10.1124/jpet.105.093948  0.085
1982 Tabata M, Alkon DL. Positive synaptic feedback in visual system of nudibranch mollusk Hermissenda crassicornis. Journal of Neurophysiology. 48: 174-91. PMID 7119843  0.085
1998 Gasparini L, Racchi M, Binetti G, Trabucchi M, Solerte SB, Alkon D, Etcheberrigaray R, Gibson G, Blass J, Paoletti R, Govoni S. Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 17-34. PMID 9438407 DOI: 10.1096/Fasebj.12.1.17  0.081
1978 Alkon DL, Grossman Y. Long-lasting depolarization and hyperpolarization in eye of Hermissenda. Journal of Neurophysiology. 41: 1328-42. PMID 212540  0.081
2017 Sen A, Nelson TJ, Alkon DL. ApoE isoforms differentially regulates cleavage and secretion of BDNF. Molecular Brain. 10: 19. PMID 28569173 DOI: 10.1186/s13041-017-0301-3  0.08
2015 Tan Z, Lucke-Wold BP, Logsdon AF, Turner RC, Tan C, Li X, Hongpaison J, Alkon DL, Simpkins JW, Rosen CL, Huber JD. Bryostatin extends tPA time window to 6h following middle cerebral artery occlusion in aged female rats. European Journal of Pharmacology. 764: 404-412. PMID 26189021 DOI: 10.1016/J.Ejphar.2015.07.035  0.079
2003 Kuzirian AM, Child FM, Epstein HT, Motta ME, Oldenburg CE, Alkon DL. Training alone, not the tripeptide RGD, modulates calexcitin in Hermissenda. The Biological Bulletin. 205: 220-2. PMID 14583539 DOI: 10.2307/1543262  0.078
2008 Micale V, Scapagnini G, Colombrita C, Mazzola C, Alkon DL, Drago F. Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 462-71. PMID 18222653 DOI: 10.1016/j.euroneuro.2007.11.006  0.077
2019 Taiz L, Alkon D, Draguhn A, Murphy A, Blatt M, Hawes C, Thiel G, Robinson DG. Plants Neither Possess nor Require Consciousness. Trends in Plant Science. PMID 31279732 DOI: 10.1016/J.Tplants.2019.05.008  0.076
1991 Hyman SD, Vogl TP, Blackwell KT, Barbour GS, Irvine JM, Alkon DL. Classification of Japanese Kanji using principal component analysis as a preprocessor to an artificial neural network Proceedings. Ijcnn-91-Seattle: International Joint Conference On Neural Networks. 233-238.  0.075
2003 Sun MK, Alkon DL. Open space swimming test to index antidepressant activity. Journal of Neuroscience Methods. 126: 35-40. PMID 12788500 DOI: 10.1016/S0165-0270(03)00068-2  0.074
2014 Nelson TJ, Sen A, Alkon DL, Sun MK. Adduct formation in liquid chromatography-triple quadrupole mass spectrometric measurement of bryostatin 1. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 944: 55-62. PMID 24291721 DOI: 10.1016/j.jchromb.2013.11.020  0.073
2022 Chirila FV, Xu G, Fontaine D, Kern G, Khan TK, Brandt J, Konishi Y, Nebe-von-Caron G, White CL, Alkon DL. Morphometric imaging biomarker identifies Alzheimer's disease even among mixed dementia patients. Scientific Reports. 12: 17675. PMID 36319674 DOI: 10.1038/s41598-022-21796-y  0.073
2008 Sun MK, Alkon DL. Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats. Behavioural Pharmacology. 19: 334-8. PMID 18622181 DOI: 10.1097/FBP.0b013e328308f239  0.069
2010 Khan TK, Alkon DL. Early diagnostic accuracy and pathophysiologic relevance of an autopsy-confirmed Alzheimer's disease peripheral biomarker. Neurobiology of Aging. 31: 889-900. PMID 18760507 DOI: 10.1016/j.neurobiolaging.2008.07.010  0.067
2014 Chirila FV, Khan TK, Alkon DL. Fibroblast aggregation rate converges with validated peripheral biomarkers for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 42: 1279-94. PMID 25024330 DOI: 10.3233/Jad-140672  0.066
2015 Khan TK, Alkon DL. Peripheral biomarkers of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 729-44. PMID 25374110 DOI: 10.3233/JAD-142262  0.063
1982 Grossman Y, Alkon DL. Voltage noise power spectra reflect ciliary movement frequencies in statocyst hair cells. Neuroscience Letters. 31: 135-40. PMID 7133549 DOI: 10.1016/0304-3940(82)90105-7  0.062
2013 Chirila FV, Khan TK, Alkon DL. Spatiotemporal complexity of fibroblast networks screens for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 165-76. PMID 22886026 DOI: 10.3233/Jad-2012-120745  0.062
2018 Farlow MR, Thompson RE, Wei LJ, Tuchman AJ, Grenier E, Crockford D, Wilke S, Benison J, Alkon DL. A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30530975 DOI: 10.3233/Jad-180759  0.057
2014 Sun MK, Alkon DL. Stress: perspectives on its impact on cognition and pharmacological treatment. Behavioural Pharmacology. 25: 410-24. PMID 25028862 DOI: 10.1097/FBP.0000000000000045  0.053
2005 Micale V, Mazzola C, Leggio G, Alkon D, Drago F. P.4.06 Behavioral modifications induced by dietary cholesterol in rats European Neuropsychopharmacology. 15: S76. DOI: 10.1016/S0924-977X(05)80199-3  0.05
2006 Sun MK, Alkon DL. Links between Alzheimer's disease and diabetes. Drugs of Today (Barcelona, Spain : 1998). 42: 481-9. PMID 16894402 DOI: 10.1358/dot.2006.42.7.973588  0.049
2004 Hatakeyama D, Inamura S, Ito E, Sakakibara M, Nelson TJ, Alkon DL. Calexcitin-like immunoreactivity in the pond snail Lymnaea stagnalis Neuroscience Research Communications. 35: 32-40. DOI: 10.1002/nrc.20017  0.049
2003 Calabrese V, Scapagnini G, Ravagna P, Colombrita C, Spadaro F, Guagliano E, Abraham NG, Alkon DL, Giuffrida Stella AM. Differential expression of heme oxygenase isoforms in rat brain by endotoxin (LPS) Journal of Neurochemistry. 85: 29-29. DOI: 10.1046/J.1471-4159.85.S2.19_5.X  0.049
2023 Alkon DL, Sun MK, Tuchman AJ, Thompson RE. Advanced Alzheimer's Disease Patients Show Safe, Significant, and Persistent Benefit in 6-Month Bryostatin Trial. Journal of Alzheimer's Disease : Jad. PMID 37742657 DOI: 10.3233/JAD-230868  0.048
2015 Tan Z, Lucke-Wold BP, Logsdon AF, Turner RC, Tan C, Li X, Hongpaison J, Alkon DL, Simpkins JW, Rosen CL, Huber JD. Bryostatin extends tPA time window to 6 h following middle cerebral artery occlusion in aged female rats European Journal of Pharmacology. 764: 404-412. DOI: 10.1016/j.ejphar.2015.07.035  0.047
1970 Green JP, Alkon DL, Schmidt DE, Szilagyi PI. Confirmation of acetylcholine in perfusates of the stimulated vagus nerve by pyrolysis gas chromatography. Life Sciences. Pt. 1: Physiology and Pharmacology. 9: 741-5. PMID 4320176  0.046
2019 Alkon DL, Thompson R, Wei LJ, Tuchman A. P4-661: REPLICATION TRIAL TO CONFIRM REVERSAL OF COGNITIVE DECLINE WITH BRYOSTATIN FOR ADVANCED ALZHEIMER'S PATIENTS IN THE ABSENCE OF MEMANTINE Alzheimer's & Dementia. 15: P1584-P1584. DOI: 10.1016/j.jalz.2019.09.027  0.046
1970 Schmidt DE, Szilagyi PI, Alkon DL, Green JP. A method for measuring nanogram quantities of acetylcholine by pyrolysis-gas chromatography: the demonstration of acetylcholine in effluents from the rat phrenic nerve-diaphragm preparation. The Journal of Pharmacology and Experimental Therapeutics. 174: 337-45. PMID 5451368  0.043
2015 Nelson TJ, Sun MK, Alkon DL. Signaling Pathways Involved in Cognitive Enhancement Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors. 11-42. DOI: 10.1016/B978-0-12-417042-1.00002-4  0.042
1971 Alkon DL, Goldberg AS, Green JP, Levi P, Liao K. Fluorophors formed from imidazoles. Analytical Biochemistry. 40: 192-9. PMID 5550145  0.039
1969 Schmidt DE, Szilagyi PI, Alkon DL, Green JP. Acetylcholine: release from neural tissue and identification by pyrolysis--gas chromatography. Science (New York, N.Y.). 165: 1370-1. PMID 5807962  0.035
2006 Thompson R, Wei LJ, Tuchman A, Alkon D. P4-199: SIGNIFICANT COGNITIVE IMPROVEMENT WITH BRYOSTATIN FOR ADVANCED ALZHEIMER'S PATIENTS IN THE ABSENCE OF MEMANTINE Alzheimer's & Dementia. 14: P1516-P1516. DOI: 10.1016/j.jalz.2018.07.020  0.034
2004 Micale V, Scapagnini G, Mazzola C, Drago F, Alkon D. P43 EFFECTS OF DIETARY CHOLESTEROL ON DEPRESSION IN RATS Behavioural Pharmacology. 15: A21. DOI: 10.1097/00008877-200409000-00083  0.031
2017 Farlow MR, Burns JM, Gorelick KJ, Crockford DR, Grenier E, Wilke S, Cooper EC, Alkon DL. BRYOSTATIN-1 IMPROVES COGNITION AND DAILY LIVING TASKS IN MODERATE TO SEVERE ALZHEIMER’S DISEASE: PRELIMINARY REPORT OF A PHASE 2 STUDY Alzheimer's & Dementia. 13: P1476. DOI: 10.1016/J.Jalz.2017.08.006  0.031
1983 Alkon DL. Sensory function of cilia Journal of Submicroscopic Cytology. 15: 173-176.  0.03
2008 Cui C, Han Y, Alkon D. P2-390: A combination strategy for the Alzheimer's disease treatment Alzheimer's & Dementia. 4: T487-T487. DOI: 10.1016/j.jalz.2008.05.1468  0.03
2011 Alkon D. What can the physician offer the patient presenting with dementia? The West Virginia Medical Journal. 107: 8. PMID 21702407  0.024
2006 Sun MK, Alkon DL. Links between Alzheimer's disease and diabetes. Timely Topics in Medicine. Cardiovascular Diseases. 10: E24. PMID 17066144  0.024
2015 Khan TK, Alkon DL. Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy. Journal of Alzheimer's Disease : Jad. 46: 817-36. PMID 26402622 DOI: 10.3233/JAD-150238  0.022
2015 Khan TK, Alkon DL. Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy Journal of Alzheimer's Disease. 46: 817-836. DOI: 10.3233/JAD-150238  0.022
2011 Alkon DL. New developments in the search for a cure. The West Virginia Medical Journal. 107: 10-3. PMID 21702408  0.022
1974 Alkon DL. Sensory interactions in the nudibranch mollusk Hermissenda crassicornis. Federation Proceedings. 33: 1083-90. PMID 4818242  0.019
1970 Alkon DL, Schmidt DE, Green JP, Szilagyi PI. The release of acetylcholine from the innervated and denervated diaphragm. The Journal of Pharmacology and Experimental Therapeutics. 174: 346-9. PMID 5451369  0.018
2008 Nelson TJ, Alkon DL. Protection against β-amyloid-induced apoptosis by peptides interacting with β-amyloid (Journal of Biological Chemistry (2007) 282, (31238-31249)) Journal of Biological Chemistry. 283: 6616.  0.018
2020 Taiz L, Alkon D, Draguhn A, Murphy A, Blatt M, Thiel G, Robinson DG. Reply to Trewavas et al. and Calvo and Trewavas. Trends in Plant Science. PMID 31926764 DOI: 10.1016/J.Tplants.2019.12.020  0.012
1993 Alkon DL. Editorial Cellular and Molecular Biology Research. 39: 545.  0.01
1971 Alkon DL. Parental deprivation. Acta Psychiatrica Scandinavica. Supplementum. 223: 1-48. PMID 5291705  0.01
Hide low-probability matches.