Donald J. Zack - Publications

Affiliations: 
1991- Ophthalmology Johns Hopkins University, Baltimore, MD 
Area:
Visual system, rhodopsin, gene expression

225 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tammia M, Mi R, Sluch VM, Zhu A, Chung T, Shinn D, Zack DJ, Höke A, Mao HQ. Egr2 overexpression in Schwann cells increases myelination frequency . Heliyon. 4: e00982. PMID 30761371 DOI: 10.1016/j.heliyon.2018.e00982  0.6
2018 Capowski EE, Samimi K, Mayerl SJ, Phillips MJ, Pinilla I, Howden SE, Saha J, Jansen AD, Edwards KL, Jager LD, Barlow K, Valiauga R, Erlichman Z, Hagstrom A, Sinha D, ... ... Zack DJ, et al. Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines. Development (Cambridge, England). PMID 30567931 DOI: 10.1242/dev.171686  0.6
2018 Sluch VM, Chamling X, Wenger C, Duan Y, Rice DS, Zack DJ. Highly efficient scarless knock-in of reporter genes into human and mouse pluripotent stem cells via transient antibiotic selection. Plos One. 13: e0201683. PMID 30496180 DOI: 10.1371/journal.pone.0201683  0.6
2018 Eldred KC, Hadyniak SE, Hussey KA, Brenerman B, Zhang PW, Chamling X, Sluch VM, Welsbie DS, Hattar S, Taylor J, Wahlin K, Zack DJ, Johnston RJ. Thyroid hormone signaling specifies cone subtypes in human retinal organoids. Science (New York, N.Y.). 362. PMID 30309916 DOI: 10.1126/science.aau6348  0.6
2018 Fligor CM, Langer KB, Sridhar A, Ren Y, Shields PK, Edler MC, Ohlemacher SK, Sluch VM, Zack DJ, Zhang C, Suter DM, Meyer JS. Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells. Scientific Reports. 8: 14520. PMID 30266927 DOI: 10.1038/s41598-018-32871-8  0.6
2018 Wang J, Zibetti C, Shang P, Sripathi SR, Zhang P, Cano M, Hoang T, Xia S, Ji H, Merbs SL, Zack DJ, Handa JT, Sinha D, Blackshaw S, Qian J. ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration. Nature Communications. 9: 1364. PMID 29636475 DOI: 10.1038/s41467-018-03856-y  0.6
2018 Fernandes KA, Mitchell KL, Patel A, Marola OJ, Shrager P, Zack DJ, Libby RT, Welsbie DS. Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury. Experimental Eye Research. PMID 29526794 DOI: 10.1016/j.exer.2018.03.007  0.6
2018 Daniszewski M, Senabouth A, Nguyen QH, Crombie DE, Lukowski SW, Kulkarni T, Sluch VM, Jabbari JS, Chamling X, Zack DJ, Pébay A, Powell JE, Hewitt AW. Single cell RNA sequencing of stem cell-derived retinal ganglion cells. Scientific Data. 5: 180013. PMID 29437159 DOI: 10.1038/sdata.2018.13  0.6
2018 Bailey JNC, Gharahkhani P, Kang JH, Butkiewicz M, Sullivan DA, Weinreb RN, Aschard H, Allingham RR, Ashley-Koch A, Lee RK, Moroi SE, Brilliant MH, Wollstein G, Schuman JS, Fingert JH, ... ... Zack DJ, et al. Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets. Investigative Ophthalmology & Visual Science. 59: 629-636. PMID 29392307 DOI: 10.1167/iovs.17-22708  0.36
2017 Wang X, Maruotti J, Majumdar S, Roman J, Mao HQ, Zack D, Elisseeff J. Collagen Vitrigels with Low-fibril Density Enhance Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cell Maturation. Journal of Tissue Engineering and Regenerative Medicine. PMID 29049869 DOI: 10.1002/term.2598  0.36
2017 Sluch VM, Chamling X, Liu MM, Berlinicke CA, Cheng J, Mitchell KL, Welsbie DS, Zack DJ. Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells. Stem Cells Translational Medicine. PMID 29024560 DOI: 10.1002/sctm.17-0059  0.68
2017 Aschard H, Kang JH, Iglesias AI, Hysi P, Cooke Bailey JN, Khawaja AP, Allingham RR, Ashley-Koch A, Lee RK, Moroi SE, Brilliant MH, Wollstein G, Schuman JS, Fingert JH, Budenz DL, ... ... Zack DJ, et al. Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis. European Journal of Human Genetics : Ejhg. PMID 28853718 DOI: 10.1038/ejhg.2017.136  0.36
2017 Liu MM, Farkas M, Spinnhirny P, Pevet P, Pierce E, Hicks D, Zack DJ. De novo assembly and annotation of the retinal transcriptome for the Nile grass rat (Arvicanthis ansorgei). Plos One. 12: e0179061. PMID 28759564 DOI: 10.1371/journal.pone.0179061  0.6
2017 Welsbie DS, Mitchell KL, Jaskula-Ranga V, Sluch VM, Yang Z, Kim J, Buehler E, Patel A, Martin SE, Zhang PW, Ge Y, Duan Y, Fuller J, Kim BJ, Hamed E, ... ... Zack DJ, et al. Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons. Neuron. 94: 1142-1154.e6. PMID 28641113 DOI: 10.1016/j.neuron.2017.06.008  0.68
2017 Wilson DR, Routkevitch D, Rui Y, Mosenia A, Wahlin KJ, Quinones-Hinojosa A, Zack DJ, Green JJ. A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28479046 DOI: 10.1016/j.ymthe.2017.04.008  0.48
2017 Wahlin KJ, Maruotti JA, Sripathi SR, Ball J, Angueyra JM, Kim C, Grebe R, Li W, Jones BW, Zack DJ. Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. Scientific Reports. 7: 766. PMID 28396597 DOI: 10.1038/s41598-017-00774-9  0.52
2017 Crombie DE, Daniszewski M, Liang HH, Kulkarni T, Li F, Lidgerwood GE, Conquest A, Hernández D, Hung SS, Gill KP, De Smit E, Kearns LS, Clarke L, Sluch VM, Chamling X, ... Zack DJ, et al. Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells. Slas Discovery. 2472555217696797. PMID 28287872 DOI: 10.1177/2472555217696797  0.6
2017 Kim EC, Toyono T, Berlinicke CA, Zack DJ, Jurkunas U, Usui T, Jun AS. Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress. Investigative Ophthalmology & Visual Science. 58: 892-900. PMID 28159976 DOI: 10.1167/iovs.16-20147  0.68
2016 Masuda T, Wan J, Yerrabelli A, Berlinicke C, Kallman A, Qian J, Zack DJ. Off Target, but Sequence-Specific, shRNA-Associated Trans-Activation of Promoter Reporters in Transient Transfection Assays. Plos One. 11: e0167867. PMID 27977714 DOI: 10.1371/journal.pone.0167867  0.6
2016 Pasquale LR, Aschard H, Kang JH, Bailey JN, Lindström S, Chasman DI, Christen WG, Allingham RR, Ashley-Koch A, Lee RK, Moroi SE, Brilliant MH, Wollstein G, Schuman JS, Fingert J, ... ... Zack DJ, et al. Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample. Menopause (New York, N.Y.). PMID 27760082 DOI: 10.1097/GME.0000000000000741  0.36
2016 Khawaja AP, Cooke Bailey JN, Kang JH, Allingham RR, Hauser MA, Brilliant M, Budenz DL, Christen WG, Fingert J, Gaasterland D, Gaasterland T, Kraft P, Lee RK, Lichter PR, Liu Y, ... ... Zack DJ, et al. Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses. Investigative Ophthalmology & Visual Science. 57: 5046-5052. PMID 27661856 DOI: 10.1167/iovs.16-20017  0.52
2016 Liu Y, Bailey JC, Helwa I, Dismuke WM, Cai J, Drewry M, Brilliant MH, Budenz DL, Christen WG, Chasman DI, Fingert JH, Gaasterland D, Gaasterland T, Gordon MO, Igo RP, ... ... Zack DJ, et al. A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Investigative Ophthalmology & Visual Science. 57: 3974-3981. PMID 27537254 DOI: 10.1167/iovs.16-19688  0.52
2016 Langouet-Astrie CJ, Yang Z, Polisetti SM, Welsbie DS, Hauswirth WW, Zack DJ, Merbs SL, Enke RA. Characterization of intravitreally delivered capsid mutant AAV2-Cre vector to induce tissue-specific mutations in murine retinal ganglion cells. Experimental Eye Research. PMID 27481653 DOI: 10.1016/j.exer.2016.07.019  0.6
2016 Pan J, Liu S, Farkas M, Consugar M, Zack DJ, Kozak I, Arevalo JF, Pierce E, Qian J, Al Kahtani E. Serum molecular signature for proliferative diabetic retinopathy in Saudi patients with type 2 diabetes. Molecular Vision. 22: 636-45. PMID 27307695  0.6
2016 Chamling X, Sluch VM, Zack DJ. The Potential of Human Stem Cells for the Study and Treatment of Glaucoma. Investigative Ophthalmology & Visual Science. 57: ORSFi1-6. PMID 27116666 DOI: 10.1167/iovs.15-18590  0.6
2016 Ouyang H, Goldberg JL, Chen S, Li W, Xu GT, Li W, Zhang K, Nussenblatt RB, Liu Y, Xie T, Chan CC, Zack DJ. Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium. International Journal of Molecular Sciences. 17. PMID 27102165 DOI: 10.3390/ijms17030415  0.52
2016 Bailey JN, Loomis SJ, Kang JH, Allingham RR, Gharahkhani P, Khor CC, Burdon KP, Aschard H, Chasman DI, Igo RP, Hysi PG, Glastonbury CA, Ashley-Koch A, Brilliant M, Brown AA, ... ... Zack DJ, et al. Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. Nature Genetics. PMID 26752265 DOI: 10.1038/ng.3482  0.52
2016 Fuller JA, Berlinicke CA, Inglese J, Zack DJ. Use of a Machine Learning-Based High Content Analysis Approach to Identify Photoreceptor Neurite Promoting Molecules. Advances in Experimental Medicine and Biology. 854: 597-603. PMID 26427464 DOI: 10.1007/978-3-319-17121-0_79  0.68
2015 Myneni S, Patel VL, Bova GS, Wang J, Ackerman CF, Berlinicke CA, Chen SH, Lindvall M, Zack DJ. Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration. Computer Methods and Programs in Biomedicine. PMID 26652980 DOI: 10.1016/j.cmpb.2015.11.001  0.68
2015 Sluch VM, Davis CO, Ranganathan V, Kerr JM, Krick K, Martin R, Berlinicke CA, Marsh-Armstrong N, Diamond JS, Mao HQ, Zack DJ. Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line. Scientific Reports. 5: 16595. PMID 26563826 DOI: 10.1038/srep16595  0.68
2015 Maruotti J, Sripathi SR, Bharti K, Fuller J, Wahlin KJ, Ranganathan V, Sluch VM, Berlinicke CA, Davis J, Kim C, Zhao L, Wan J, Qian J, Corneo B, Temple S, ... ... Zack DJ, et al. Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26269569 DOI: 10.1073/pnas.1422818112  0.68
2015 Oliver V, Jaffe AE, Song J, Wang G, Zhang P, Branham KE, Swaroop A, Eberhart CG, Zack DJ, Qian J, Merbs SL. Differential DNA Methylation Identified in the Blood and Retina of AMD Patients. Epigenetics : Official Journal of the Dna Methylation Society. 0. PMID 26067391 DOI: 10.1080/15592294.2015.1060388  0.68
2015 Masuda T, Berlinicke CA, Zack DJ. Gene regulation: it matters who you hang out with. Neuron. 86: 7-9. PMID 25856477 DOI: 10.1016/j.neuron.2015.03.057  0.68
2015 Wan J, Oliver VF, Wang G, Zhu H, Zack DJ, Merbs SL, Qian J. Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation. Bmc Genomics. 16: 49. PMID 25652663 DOI: 10.1186/s12864-015-1271-4  0.68
2015 Elachouri G, Lee-Rivera I, Clérin E, Argentini M, Fridlich R, Blond F, Ferracane V, Yang Y, Raffelsberger W, Wan J, Bennett J, Sahel JA, Zack DJ, Léveillard T. Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage. Free Radical Biology & Medicine. 81: 22-9. PMID 25596499 DOI: 10.1016/j.freeradbiomed.2015.01.003  0.68
2014 Liu Y, Garrett ME, Yaspan BL, Bailey JC, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert JH, Gaasterland D, Gaasterland T, Kang JH, Lee RK, Lichter P, Moroi SE, ... ... Zack DJ, et al. DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma. Investigative Ophthalmology & Visual Science. 55: 8251-8. PMID 25414181 DOI: 10.1167/iovs.14-15712  0.68
2014 Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ. The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15356-68. PMID 25392503 DOI: 10.1523/JNEUROSCI.2089-14.2014  0.68
2014 Ranganathan V, Wahlin K, Maruotti J, Zack DJ. Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs. Nature Communications. 5: 4516. PMID 25105359 DOI: 10.1038/ncomms5516  0.68
2014 Bailey JN, Yaspan BL, Pasquale LR, Hauser MA, Kang JH, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert J, Gaasterland D, Gaasterland T, Kraft P, Lee RK, Lichter PR, ... ... Zack DJ, et al. Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. Human Genetics. 133: 1319-30. PMID 25037249 DOI: 10.1007/s00439-014-1468-7  0.68
2014 Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, ... ... Zack DJ, et al. Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration. Human Molecular Genetics. 23: 5827-37. PMID 24899048 DOI: 10.1093/hmg/ddu276  0.68
2014 Carnes MU, Liu YP, Allingham RR, Whigham BT, Havens S, Garrett ME, Qiao C, Katsanis N, Wiggs JL, Pasquale LR, Ashley-Koch A, Oh EC, Hauser MA. Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma. Plos Genetics. 10: e1004372. PMID 24875647 DOI: 10.1371/journal.pgen.1004372  0.68
2014 Sluch VM, Zack DJ. Stem cells, retinal ganglion cells and glaucoma. Developments in Ophthalmology. 53: 111-21. PMID 24732765 DOI: 10.1159/000358409  0.68
2014 Léveillard T, Fridlich R, Clérin E, Aït-Ali N, Millet-Puel G, Jaillard C, Yang Y, Zack D, Van-Dorsselaer A, Sahel JA. Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors Comptes Rendus - Biologies. 337: 207-213. PMID 24702847 DOI: 10.1016/j.crvi.2013.12.002  0.68
2014 Fuller JA, Shaw GC, Bonnet-Wersinger D, Hansen BS, Berlinicke CA, Inglese J, Zack DJ. A high content screening approach to identify molecules neuroprotective for photoreceptor cells. Advances in Experimental Medicine and Biology. 801: 773-81. PMID 24664770 DOI: 10.1007/978-1-4614-3209-8_97  0.68
2014 Wahlin KJ, Maruotti J, Zack DJ. Modeling retinal dystrophies using patient-derived induced pluripotent stem cells. Advances in Experimental Medicine and Biology. 801: 157-64. PMID 24664693 DOI: 10.1007/978-1-4614-3209-8_20  0.68
2014 Masuda T, Wahlin K, Wan J, Hu J, Maruotti J, Yang X, Iacovelli J, Wolkow N, Kist R, Dunaief JL, Qian J, Zack DJ, Esumi N. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. The Journal of Biological Chemistry. 289: 12908-21. PMID 24634209 DOI: 10.1074/jbc.M114.556738  0.68
2014 Kang JH, Loomis SJ, Yaspan BL, Bailey JC, Weinreb RN, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Gaasterland D, Gaasterland T, Friedman DS, McCarty CA, Moroi SE, ... ... Zack DJ, et al. Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma. Eye (London, England). 28: 662-71. PMID 24603425 DOI: 10.1038/eye.2014.42  0.68
2014 Loomis SJ, Kang JH, Weinreb RN, Yaspan BL, Cooke Bailey JN, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, ... ... Zack DJ, et al. Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss. Ophthalmology. 121: 508-16. PMID 24572674 DOI: 10.1016/j.ophtha.2013.09.012  0.68
2014 Hiebler S, Masuda T, Hacia JG, Moser AB, Faust PL, Liu A, Chowdhury N, Huang N, Lauer A, Bennett J, Watkins PA, Zack DJ, Braverman NE, Raymond GV, Steinberg SJ. The Pex1-G844D mouse: a model for mild human Zellweger spectrum disorder. Molecular Genetics and Metabolism. 111: 522-32. PMID 24503136 DOI: 10.1016/j.ymgme.2014.01.008  0.68
2014 Ozel AB, Moroi SE, Reed DM, Nika M, Schmidt CM, Akbari S, Scott K, Rozsa F, Pawar H, Musch DC, Lichter PR, Gaasterland D, Branham K, Gilbert J, Garnai SJ, ... ... Zack D, et al. Genome-wide association study and meta-analysis of intraocular pressure. Human Genetics. 133: 41-57. PMID 24002674 DOI: 10.1007/s00439-013-1349-5  0.68
2013 Oliver VF, Franchina M, Jaffe AE, Branham KE, Othman M, Heckenlively JR, Swaroop A, Campochiaro B, Vote BJ, Craig JE, Saffery R, Mackey DA, Qian J, Zack DJ, Hewitt AW, et al. Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration. Cell Reports. 5: 1527-35. PMID 24373284 DOI: 10.1016/j.celrep.2013.11.042  0.68
2013 Bhise NS, Wahlin KJ, Zack DJ, Green JJ. Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells. International Journal of Nanomedicine. 8: 4641-58. PMID 24348039 DOI: 10.2147/IJN.S53830  0.68
2013 Wahlin KJ, Enke RA, Fuller JA, Kalesnykas G, Zack DJ, Merbs SL. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. Plos One. 8: e79140. PMID 24244436 DOI: 10.1371/journal.pone.0079140  0.68
2013 Wan J, Oliver VF, Zhu H, Zack DJ, Qian J, Merbs SL. Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs. Nucleic Acids Research. 41: 8503-14. PMID 23887936 DOI: 10.1093/nar/gkt652  0.68
2013 Pasquale LR, Loomis SJ, Weinreb RN, Kang JH, Yaspan BL, Bailey JC, Gaasterland D, Gaasterland T, Lee RK, Scott WK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, ... ... Zack DJ, et al. Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. Molecular Vision. 19: 1471-81. PMID 23869166  0.68
2013 Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack DJ, Esumi N. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Molecular Vision. 19: 1371-86. PMID 23805044  0.68
2013 Hammoudeh M, Zack DJ, Li W, Stewart VM, Koenig AS. Associations between inflammation, nocturnal back pain and fatigue in ankylosing spondylitis and improvements with etanercept therapy. The Journal of International Medical Research. 41: 1150-9. PMID 23803306 DOI: 10.1177/0300060513488501  0.52
2013 Oliver VF, Wan J, Agarwal S, Zack DJ, Qian J, Merbs SL. A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples. Epigenetics & Chromatin. 6: 17. PMID 23759032 DOI: 10.1186/1756-8935-6-17  0.68
2013 van de Ven JP, Nilsson SC, Tan PL, Buitendijk GH, Ristau T, Mohlin FC, Nabuurs SB, Schoenmaker-Koller FE, Smailhodzic D, Campochiaro PA, Zack DJ, Duvvari MR, Bakker B, Paun CC, Boon CJ, et al. A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nature Genetics. 45: 813-7. PMID 23685748 DOI: 10.1038/ng.2640  0.68
2013 Liu MM, Zack DJ. Alternative splicing and retinal degeneration. Clinical Genetics. 84: 142-9. PMID 23647439 DOI: 10.1111/cge.12181  0.68
2013 Maruotti J, Wahlin K, Gorrell D, Bhutto I, Lutty G, Zack DJ. A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells. Stem Cells Translational Medicine. 2: 341-54. PMID 23585288 DOI: 10.5966/sctm.2012-0106  0.68
2013 Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Zack DJ, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/msb.2013.12  0.68
2013 Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, et al. Seven new loci associated with age-related macular degeneration. Nature Genetics. 45: 433-9, 439e1-2. PMID 23455636 DOI: 10.1038/ng.2578  0.52
2013 Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, ... ... Zack DJ, et al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4045-50. PMID 23431148 DOI: 10.1073/pnas.1211284110  0.68
2013 Nasonkin IO, Merbs SL, Lazo K, Oliver VF, Brooks M, Patel K, Enke RA, Nellissery J, Jamrich M, Le YZ, Bharti K, Fariss RN, Rachel RA, Zack DJ, Rodriguez-Boulan EJ, et al. Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis. Development (Cambridge, England). 140: 1330-41. PMID 23406904 DOI: 10.1242/dev.086603  0.68
2013 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S. Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E507-16. PMID 23341629 DOI: 10.1073/pnas.1212655110  0.68
2013 Pasquale LR, Loomis SJ, Kang JH, Yaspan BL, Abdrabou W, Budenz DL, Chen TC, Delbono E, Friedman DS, Gaasterland D, Gaasterland T, Grosskreutz CL, Lee RK, Lichter PR, Liu Y, ... ... Zack DJ, et al. CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. American Journal of Ophthalmology. 155: 342-353.e5. PMID 23111177 DOI: 10.1016/j.ajo.2012.07.023  0.68
2013 Wiggs JL, Hauser MA, Abdrabou W, Allingham RR, Budenz DL, Delbono E, Friedman DS, Kang JH, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Loomis S, Liu Y, McCarty C, ... ... Zack D, et al. The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables. Journal of Glaucoma. 22: 517-25. PMID 22828004 DOI: 10.1097/IJG.0b013e31824d4fd8  0.68
2012 Hwang W, Hackler L, Wu G, Ji H, Zack DJ, Qian J. Dynamics of regulatory networks in the developing mouse retina. Plos One. 7: e46521. PMID 23056331 DOI: 10.1371/journal.pone.0046521  0.68
2012 Maruotti J, Thein T, Zack DJ, Esumi N. MITF-M, a 'melanocyte-specific' isoform, is expressed in the adult retinal pigment epithelium. Pigment Cell & Melanoma Research. 25: 641-4. PMID 22765275 DOI: 10.1111/j.1755-148X.2012.01033.x  0.68
2012 Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, ... Zack DJ, et al. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology. 119: 1874-85. PMID 22705344 DOI: 10.1016/j.ophtha.2012.03.014  0.68
2012 Hackler L, Masuda T, Oliver VF, Merbs SL, Zack DJ. Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation. Methods in Molecular Biology (Clifton, N.J.). 884: 289-304. PMID 22688715 DOI: 10.1007/978-1-61779-848-1_21  0.68
2012 Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Hawthorne F, Budenz DL, Friedman DS, Gaasterland D, Haines J, Kang JH, Lee R, Lichter P, Liu Y, ... ... Zack DJ, et al. Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. Investigative Ophthalmology & Visual Science. 53: 4468-74. PMID 22661486 DOI: 10.1167/iovs.12-9784  0.68
2012 Kalesnykas G, Oglesby EN, Zack DJ, Cone FE, Steinhart MR, Tian J, Pease ME, Quigley HA. Retinal ganglion cell morphology after optic nerve crush and experimental glaucoma. Investigative Ophthalmology & Visual Science. 53: 3847-57. PMID 22589442 DOI: 10.1167/iovs.12-9712  0.68
2012 Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W, Budenz DL, Caprioli J, Crenshaw A, Crooks K, Delbono E, ... ... Zack D, et al. Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. Plos Genetics. 8: e1002654. PMID 22570617 DOI: 10.1371/journal.pgen.1002654  0.68
2012 Merbs SL, Khan MA, Hackler L, Oliver VF, Wan J, Qian J, Zack DJ. Cell-specific DNA methylation patterns of retina-specific genes. Plos One. 7: e32602. PMID 22403679 DOI: 10.1371/journal.pone.0032602  0.68
2012 Toops KA, Berlinicke C, Zack DJ, Nickells RW. Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity. Investigative Ophthalmology & Visual Science. 53: 2046-61. PMID 22395888 DOI: 10.1167/iovs.11-8646  0.68
2012 Berlinicke CA, Ackermann CF, Chen SH, Schulze C, Shafranovich Y, Myneni S, Patel VL, Wang J, Zack DJ, Lindvall M, Bova GS. High-content screening data management for drug discovery in a small- to medium-size laboratory: results of a collaborative pilot study focused on user expectations as indicators of effectiveness. Journal of Laboratory Automation. 17: 255-65. PMID 22357564 DOI: 10.1177/2211068211431207  0.68
2012 Oglesby E, Quigley HA, Zack DJ, Cone FE, Steinhart MR, Tian J, Pease ME, Kalesnykas G. Semi-automated, quantitative analysis of retinal ganglion cell morphology in mice selectively expressing yellow fluorescent protein. Experimental Eye Research. 96: 107-15. PMID 22210127 DOI: 10.1016/j.exer.2011.12.013  0.68
2011 Raychaudhuri S, Iartchouk O, Chin K, Tan PL, Tai AK, Ripke S, Gowrisankar S, Vemuri S, Montgomery K, Yu Y, Reynolds R, Zack DJ, Campochiaro B, Campochiaro P, Katsanis N, et al. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nature Genetics. 43: 1232-6. PMID 22019782 DOI: 10.1038/ng.976  0.68
2011 Wan J, Masuda T, Hackler L, Torres KM, Merbs SL, Zack DJ, Qian J. Dynamic usage of alternative splicing exons during mouse retina development. Nucleic Acids Research. 39: 7920-30. PMID 21724604 DOI: 10.1093/nar/gkr545  0.68
2011 Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, ... ... Zack DJ, et al. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Human Molecular Genetics. 20: 3699-709. PMID 21665990 DOI: 10.1093/hmg/ddr270  0.68
2011 Quigley HA, Cone FE, Gelman SE, Yang Z, Son JL, Oglesby EN, Pease ME, Zack DJ. Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice. Experimental Eye Research. 92: 299-305. PMID 21272576 DOI: 10.1016/j.exer.2011.01.006  0.68
2011 Zigler JS, Zhang C, Grebe R, Sehrawat G, Hackler L, Adhya S, Hose S, McLeod DS, Bhutto I, Barbour W, Parthasarathy G, Zack DJ, Sergeev Y, Lutty GA, Handa JT, et al. Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat. Journal of Cell Science. 124: 523-31. PMID 21266465 DOI: 10.1242/jcs.078790  0.68
2011 Baehr W, Wensel T, Hageman G, Wu S, Zack D. Retinal ganglion cells: development, function, and disease. Vision Research. 51: 223. PMID 21251506 DOI: 10.1016/j.visres.2011.01.005  0.68
2011 Iacovelli J, Zhao C, Wolkow N, Veldman P, Gollomp K, Ojha P, Lukinova N, King A, Feiner L, Esumi N, Zack DJ, Pierce EA, Vollrath D, Dunaief JL. Generation of Cre transgenic mice with postnatal RPE-specific ocular expression. Investigative Ophthalmology & Visual Science. 52: 1378-83. PMID 21212186 DOI: 10.1167/iovs.10-6347  0.68
2011 Nguyen JV, Soto I, Kim KY, Bushong EA, Oglesby E, Valiente-Soriano FJ, Yang Z, Davis CH, Bedont JL, Son JL, Wei JO, Buchman VL, Zack DJ, Vidal-Sanz M, Ellisman MH, et al. Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 1176-81. PMID 21199938 DOI: 10.1073/pnas.1013965108  0.68
2011 Yang Z, Zack DJ. What has gene expression profiling taught us about glaucoma? Experimental Eye Research. 93: 191-5. PMID 20946895 DOI: 10.1016/j.exer.2010.10.001  0.68
2010 Wahlin KJ, Hackler L, Adler R, Zack DJ. Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina. The Journal of Comparative Neurology. 518: 4938-62. PMID 21031560 DOI: 10.1002/cne.22499  0.68
2010 Lambard S, Reichman S, Berlinicke C, Niepon ML, Goureau O, Sahel JA, Léveillard T, Zack DJ. Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity. Plos One. 5: e13075. PMID 20949100 DOI: 10.1371/journal.pone.0013075  0.68
2010 Hu J, Wan J, Hackler L, Zack DJ, Qian J. Computational analysis of tissue-specific gene networks: application to murine retinal functional studies. Bioinformatics (Oxford, England). 26: 2289-97. PMID 20616386 DOI: 10.1093/bioinformatics/btq408  0.6
2010 Riazuddin SA, Iqbal M, Wang Y, Masuda T, Chen Y, Bowne S, Sullivan LS, Waseem NH, Bhattacharya S, Daiger SP, Zhang K, Khan SN, Riazuddin S, Hejtmancik JF, Sieving PA, ... Zack DJ, et al. A splice-site mutation in a retina-specific exon of BBS8 causes nonsyndromic retinitis pigmentosa. American Journal of Human Genetics. 86: 805-12. PMID 20451172 DOI: 10.1016/j.ajhg.2010.04.001  0.68
2010 Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W. Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. Journal of Neurochemistry. 114: 419-29. PMID 20412383 DOI: 10.1111/j.1471-4159.2010.06752.x  0.68
2010 Neale BM, Fagerness J, Reynolds R, Sobrin L, Parker M, Raychaudhuri S, Tan PL, Oh EC, Merriam JE, Souied E, Bernstein PS, Li B, Frederick JM, Zhang K, Brantley MA, ... ... Zack DJ, et al. Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proceedings of the National Academy of Sciences of the United States of America. 107: 7395-400. PMID 20385826 DOI: 10.1073/pnas.0912019107  0.68
2010 Miki A, Miki K, Ueno S, Wersinger DM, Berlinicke C, Shaw GC, Usui S, Wang Y, Zack DJ, Campochiaro PA. Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells. Journal of Cellular Physiology. 224: 262-72. PMID 20232317 DOI: 10.1002/jcp.22129  0.68
2010 Yang Z, Tong Z, Chen Y, Zeng J, Lu F, Sun X, Zhao C, Wang K, Davey L, Chen H, London N, Muramatsu D, Salasar F, Carmona R, Kasuga D, ... ... Zack DJ, et al. Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. Plos Genetics. 6: e1000836. PMID 20140183 DOI: 10.1371/journal.pgen.1000836  0.68
2010 Hackler L, Wan J, Swaroop A, Qian J, Zack DJ. MicroRNA profile of the developing mouse retina. Investigative Ophthalmology & Visual Science. 51: 1823-31. PMID 19933188 DOI: 10.1167/iovs.09-4657  0.68
2010 Reichman S, Kalathur RK, Lambard S, Aït-Ali N, Yang Y, Lardenois A, Ripp R, Poch O, Zack DJ, Sahel JA, Léveillard T. The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina. Human Molecular Genetics. 19: 250-61. PMID 19843539 DOI: 10.1093/hmg/ddp484  0.68
2010 Baehr W, Hageman G, Wensel T, Wu S, Zack D. Mechanisms of macular degeneration Vision Research. 50: 637. DOI: 10.1016/j.visres.2010.02.007  0.68
2009 Yin Y, Cui Q, Gilbert HY, Yang Y, Yang Z, Berlinicke C, Li Z, Zaverucha-do-Valle C, He H, Petkova V, Zack DJ, Benowitz LI. Oncomodulin links inflammation to optic nerve regeneration. Proceedings of the National Academy of Sciences of the United States of America. 106: 19587-92. PMID 19875691 DOI: 10.1073/pnas.0907085106  0.68
2009 Wan J, Lin J, Zack DJ, Qian J. Relating periodicity of nucleosome organization and gene regulation. Bioinformatics (Oxford, England). 25: 1782-8. PMID 19447785 DOI: 10.1093/bioinformatics/btp323  0.68
2009 Pease ME, Zack DJ, Berlinicke C, Bloom K, Cone F, Wang Y, Klein RL, Hauswirth WW, Quigley HA. Effect of CNTF on retinal ganglion cell survival in experimental glaucoma. Investigative Ophthalmology & Visual Science. 50: 2194-200. PMID 19060281 DOI: 10.1167/iovs.08-3013  0.68
2009 Esumi N, Kachi S, Hackler L, Masuda T, Yang Z, Campochiaro PA, Zack DJ. BEST1 expression in the retinal pigment epithelium is modulated by OTX family members. Human Molecular Genetics. 18: 128-41. PMID 18849347 DOI: 10.1093/hmg/ddn323  0.68
2008 Chowers I, Meir T, Lederman M, Goldenberg-Cohen N, Cohen Y, Banin E, Averbukh E, Hemo I, Pollack A, Axer-Siegel R, Weinstein O, Hoh J, Zack DJ, Galbinur T. Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel. Molecular Vision. 14: 2263-71. PMID 19065273  0.68
2008 Yu X, Lin J, Zack DJ, Mendell JT, Qian J. Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Research. 36: 6494-503. PMID 18927108 DOI: 10.1093/nar/gkn712  0.68
2008 Yang Z, Stratton C, Francis PJ, Kleinman ME, Tan PL, Gibbs D, Tong Z, Chen H, Constantine R, Yang X, Chen Y, Zeng J, Davey L, Ma X, Hau VS, ... ... Zack DJ, et al. Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. The New England Journal of Medicine. 359: 1456-63. PMID 18753640 DOI: 10.1056/NEJMoa0802437  0.68
2008 Ueno S, Pease ME, Wersinger DM, Masuda T, Vinores SA, Licht T, Zack DJ, Quigley H, Keshet E, Campochiaro PA. Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. Journal of Cellular Physiology. 217: 13-22. PMID 18543272 DOI: 10.1002/jcp.21445  0.68
2008 Liu X, Yu X, Zack DJ, Zhu H, Qian J. TiGER: a database for tissue-specific gene expression and regulation. Bmc Bioinformatics. 9: 271. PMID 18541026 DOI: 10.1186/1471-2105-9-271  0.68
2008 Le YZ, Zheng W, Rao PC, Zheng L, Anderson RE, Esumi N, Zack DJ, Zhu M. Inducible expression of cre recombinase in the retinal pigmented epithelium. Investigative Ophthalmology & Visual Science. 49: 1248-53. PMID 18326755 DOI: 10.1167/iovs.07-1105  0.68
2008 Sinha D, Klise A, Sergeev Y, Hose S, Bhutto IA, Hackler L, Malpic-Llanos T, Samtani S, Grebe R, Goldberg MF, Hejtmancik JF, Nath A, Zack DJ, Fariss RN, McLeod DS, et al. betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development. Molecular and Cellular Neurosciences. 37: 85-95. PMID 17931883 DOI: 10.1016/j.mcn.2007.08.016  0.68
2007 Yang Z, Quigley HA, Pease ME, Yang Y, Qian J, Valenta D, Zack DJ. Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms. Investigative Ophthalmology & Visual Science. 48: 5539-48. PMID 18055803 DOI: 10.1167/iovs.07-0542  0.68
2007 Yu X, Lin J, Zack DJ, Qian J. Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors. Bmc Bioinformatics. 8: 437. PMID 17996093 DOI: 10.1186/1471-2105-8-437  0.68
2007 Xu H, Sta Iglesia DD, Kielczewski JL, Valenta DF, Pease ME, Zack DJ, Quigley HA. Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes. Investigative Ophthalmology & Visual Science. 48: 1674-82. PMID 17389499 DOI: 10.1167/iovs.06-1034  0.68
2007 Li G, Anderson RE, Tomita H, Adler R, Liu X, Zack DJ, Rajala RV. Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 203-11. PMID 17202487 DOI: 10.1523/JNEUROSCI.0445-06.2007  0.68
2007 Esumi N, Kachi S, Campochiaro PA, Zack DJ. VMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE family. The Journal of Biological Chemistry. 282: 1838-50. PMID 17085443 DOI: 10.1074/jbc.M609517200  0.68
2007 Kerrison JB, Zack DJ. Neurite outgrowth in retinal ganglion cell culture. Methods in Molecular Biology (Clifton, N.J.). 356: 427-34. PMID 16988421  0.68
2006 Lin J, Zack DJ, Qian J. Transcriptional regulatory network prediction. Biotechnology & Genetic Engineering Reviews. 22: 45-62. PMID 18476325  0.68
2006 Yu X, Lin J, Zack DJ, Qian J. Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues. Nucleic Acids Research. 34: 4925-36. PMID 16982645 DOI: 10.1093/nar/gkl595  0.68
2006 Qian J, Lin J, Zack DJ. Characterization of binding sites of eukaryotic transcription factors. Genomics, Proteomics & Bioinformatics. 4: 67-79. PMID 16970547 DOI: 10.1016/S1672-0229(06)60019-3  0.68
2006 Levine RA, Demirel S, Fan J, Keltner JL, Johnson CA, Kass MA. Asymmetries and visual field summaries as predictors of glaucoma in the ocular hypertension treatment study. Investigative Ophthalmology & Visual Science. 47: 3896-903. PMID 16936102 DOI: 10.1167/iovs.05-0469  0.68
2006 Chowers I, Wong R, Dentchev T, Farkas RH, Iacovelli J, Gunatilaka TL, Medeiros NE, Presley JB, Campochiaro PA, Curcio CA, Dunaief JL, Zack DJ. The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration. Investigative Ophthalmology & Visual Science. 47: 2135-40. PMID 16639025 DOI: 10.1167/iovs.05-1135  0.68
2006 Balasubramanian D, Kaufman PL. Research opportunities in vision: a report of the U.S.-Indo workshops on collaborative research. Investigative Ophthalmology & Visual Science. 47: 1717-35. PMID 16638973 DOI: 10.1167/iovs.06-0071  0.68
2006 Kachi S, Esumi N, Zack DJ, Campochiaro PA. Sustained expression after nonviral ocular gene transfer using mammalian promoters. Gene Therapy. 13: 798-804. PMID 16467860 DOI: 10.1038/sj.gt.3302700  0.68
2006 Yu X, Lin J, Masuda T, Esumi N, Zack DJ, Qian J. Genome-wide prediction and characterization of interactions between transcription factors in Saccharomyces cerevisiae. Nucleic Acids Research. 34: 917-27. PMID 16464824 DOI: 10.1093/nar/gkj487  0.68
2006 Dorval KM, Bobechko BP, Fujieda H, Chen S, Zack DJ, Bremner R. CHX10 targets a subset of photoreceptor genes. The Journal of Biological Chemistry. 281: 744-51. PMID 16236706 DOI: 10.1074/jbc.M509470200  0.68
2005 Otteson DC, Tsujikawa M, Gunatilaka T, Malicki J, Zack DJ. Genomic organization of zebrafish cone-rod homeobox gene and exclusion as a candidate gene for retinal degeneration in niezerka and mikre oko. Molecular Vision. 11: 986-95. PMID 16319818  0.68
2005 Bradford RL, Wang C, Zack DJ, Adler R. Roles of cell-intrinsic and microenvironmental factors in photoreceptor cell differentiation. Developmental Biology. 286: 31-45. PMID 16120439 DOI: 10.1016/j.ydbio.2005.07.002  0.68
2005 Kerrison JB, Duh EJ, Yu Y, Otteson DC, Zack DJ. A system for inducible gene expression in retinal ganglion cells. Investigative Ophthalmology & Visual Science. 46: 2932-9. PMID 16043868 DOI: 10.1167/iovs.04-1237  0.68
2005 Qian J, Esumi N, Chen Y, Wang Q, Chowers I, Zack DJ. Identification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation. Nucleic Acids Research. 33: 3479-91. PMID 15967807 DOI: 10.1093/nar/gki658  0.68
2005 Otteson DC, Lai H, Liu Y, Zack DJ. Zinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elements. Bmc Molecular Biology. 6: 15. PMID 15963234 DOI: 10.1186/1471-2199-6-15  0.68
2005 Oshima Y, Oshima S, Nambu H, Kachi S, Takahashi K, Umeda N, Shen J, Dong A, Apte RS, Duh E, Hackett SF, Okoye G, Ishibashi K, Handa J, Melia M, ... ... Zack DJ, et al. Different effects of angiopoietin-2 in different vascular beds: new vessels are most sensitive. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 963-5. PMID 15802489 DOI: 10.1096/fj.04-2209fje  0.68
2005 Kachi S, Oshima Y, Esumi N, Kachi M, Rogers B, Zack DJ, Campochiaro PA. Nonviral ocular gene transfer. Gene Therapy. 12: 843-51. PMID 15789063 DOI: 10.1038/sj.gt.3302475  0.68
2005 Kerrison JB, Lewis RN, Otteson DC, Zack DJ. Bone morphogenetic proteins promote neurite outgrowth in retinal ganglion cells. Molecular Vision. 11: 208-15. PMID 15788999  0.68
2004 Oshima Y, Oshima S, Nambu H, Kachi S, Hackett SF, Melia M, Kaleko M, Connelly S, Esumi N, Zack DJ, Campochiaro PA. Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization. Journal of Cellular Physiology. 201: 393-400. PMID 15389527 DOI: 10.1002/jcp.20110  0.68
2004 Yang Z, Li Y, Jiang L, Karan G, Moshfeghi DM, O'Connor ST, Li X, Yu Z, Lewis H, Zack DJ, Jacobson SG, Zhang K. A novel RDS/peripherin gene mutation associated with diverse macular phenotypes Ophthalmic Genetics. 25: 133-145. PMID 15370544 DOI: 10.1080/13816810490514388  0.68
2004 Hackam AS, Qian J, Liu D, Gunatilaka T, Farkas RH, Chowers I, Kageyama M, Parmigiani G, Zack DJ. Comparative gene expression analysis of murine retina and brain. Molecular Vision. 10: 637-49. PMID 15359217  0.68
2004 Hackam AS, Strom R, Liu D, Qian J, Wang C, Otteson D, Gunatilaka T, Farkas RH, Chowers I, Kageyama M, Leveillard T, Sahel JA, Campochiaro PA, Parmigiani G, Zack DJ. Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Investigative Ophthalmology & Visual Science. 45: 2929-42. PMID 15326104 DOI: 10.1167/iovs.03-1184  0.68
2004 Otteson DC, Liu Y, Lai H, Wang C, Gray S, Jain MK, Zack DJ. Kruppel-like factor 15, a zinc-finger transcriptional regulator, represses the rhodopsin and interphotoreceptor retinoid-binding protein promoters. Investigative Ophthalmology & Visual Science. 45: 2522-30. PMID 15277472 DOI: 10.1167/iovs.04-0072  0.68
2004 Farkas RH, Qian J, Goldberg JL, Quigley HA, Zack DJ. Gene expression profiling of purified rat retinal ganglion cells. Investigative Ophthalmology & Visual Science. 45: 2503-13. PMID 15277470 DOI: 10.1167/iovs.03-1391  0.68
2004 Zareparsi S, Hero A, Zack DJ, Williams RW, Swaroop A. Seeing the unseen: Microarray-based gene expression profiling in vision. Investigative Ophthalmology & Visual Science. 45: 2457-62. PMID 15277464 DOI: 10.1167/iovs.04-0183  0.68
2004 Chowers I, Kim Y, Farkas RH, Gunatilaka TL, Hackam AS, Campochiaro PA, Finnemann SC, Zack DJ. Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Investigative Ophthalmology & Visual Science. 45: 2098-106. PMID 15223782 DOI: 10.1167/iovs.03-0863  0.68
2004 Wahlin KJ, Lim L, Grice EA, Campochiaro PA, Zack DJ, Adler R. A method for analysis of gene expression in isolated mouse photoreceptor and Müller cells. Molecular Vision. 10: 366-75. PMID 15205663  0.68
2004 Farkas RH, Chowers I, Hackam AS, Kageyama M, Nickells RW, Otteson DC, Duh EJ, Wang C, Valenta DF, Gunatilaka TL, Pease ME, Quigley HA, Zack DJ. Increased expression of iron-regulating genes in monkey and human glaucoma. Investigative Ophthalmology & Visual Science. 45: 1410-7. PMID 15111596 DOI: 10.1167/iovs.03-0872  0.68
2004 Duh EJ, Yang HS, Haller JA, De Juan E, Humayun MS, Gehlbach P, Melia M, Pieramici D, Harlan JB, Campochiaro PA, Zack DJ. Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. American Journal of Ophthalmology. 137: 668-74. PMID 15059706 DOI: 10.1016/j.ajo.2003.11.015  0.68
2004 Nambu H, Nambu R, Oshima Y, Hackett SF, Okoye G, Wiegand S, Yancopoulos G, Zack DJ, Campochiaro PA. Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier. Gene Therapy. 11: 865-73. PMID 15042118 DOI: 10.1038/sj.gt.3302230  0.68
2004 Wang QL, Chen S, Esumi N, Swain PK, Haines HS, Peng G, Melia BM, McIntosh I, Heckenlively JR, Jacobson SG, Stone EM, Swaroop A, Zack DJ. QRX, a novel homeobox gene, modulates photoreceptor gene expression. Human Molecular Genetics. 13: 1025-40. PMID 15028672 DOI: 10.1093/hmg/ddh117  0.68
2004 Pittler SJ, Zhang Y, Chen S, Mears AJ, Zack DJ, Ren Z, Swain PK, Yao S, Swaroop A, White JB. Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity. The Journal of Biological Chemistry. 279: 19800-7. PMID 15001570 DOI: 10.1074/jbc.M401864200  0.68
2004 Esumi N, Oshima Y, Li Y, Campochiaro PA, Zack DJ. Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation. The Journal of Biological Chemistry. 279: 19064-73. PMID 14982938 DOI: 10.1074/jbc.M309881200  0.68
2004 Chowers I, Esumi N, Campochiaro P, Zack DJ. Studies on retinal and retinal pigment epithelial gene expression. Novartis Foundation Symposium. 255: 131-45; discussion 1. PMID 14750601  0.68
2003 Chowers I, Liu D, Farkas RH, Gunatilaka TL, Hackam AS, Bernstein SL, Campochiaro PA, Parmigiani G, Zack DJ. Gene expression variation in the adult human retina. Human Molecular Genetics. 12: 2881-93. PMID 14519682 DOI: 10.1093/hmg/ddg326  0.68
2003 Martin KR, Quigley HA, Zack DJ, Levkovitch-Verbin H, Kielczewski J, Valenta D, Baumrind L, Pease ME, Klein RL, Hauswirth WW. Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Investigative Ophthalmology & Visual Science. 44: 4357-65. PMID 14507880 DOI: 10.1167/iovs.02-1332  0.68
2003 Chowers I, Gunatilaka TL, Farkas RH, Qian J, Hackam AS, Duh E, Kageyama M, Wang C, Vora A, Campochiaro PA, Zack DJ. Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. Investigative Ophthalmology & Visual Science. 44: 3732-41. PMID 12939286 DOI: 10.1167/iovs.02-1080  0.68
2003 Levkovitch-Verbin H, Quigley HA, Martin KR, Zack DJ, Pease ME, Valenta DF. A model to study differences between primary and secondary degeneration of retinal ganglion cells in rats by partial optic nerve transection. Investigative Ophthalmology & Visual Science. 44: 3388-93. PMID 12882786 DOI: 10.1167/iovs.02-0646  0.68
2003 Hackam AS, Bradford RL, Bakhru RN, Shah RM, Farkas R, Zack DJ, Adler R. Gene discovery in the embryonic chick retina. Molecular Vision. 9: 262-76. PMID 12819621  0.68
2003 Okoye G, Zimmer J, Sung J, Gehlbach P, Deering T, Nambu H, Hackett S, Melia M, Esumi N, Zack DJ, Campochiaro PA. Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4164-72. PMID 12764104  0.68
2003 Pianta MJ, Aleman TS, Cideciyan AV, Sunness JS, Li Y, Campochiaro BA, Campochiaro PA, Zack DJ, Stone EM, Jacobson SG. In vivo micropathology of Best macular dystrophy with optical coherence tomography. Experimental Eye Research. 76: 203-11. PMID 12565808 DOI: 10.1016/S0014-4835(02)00280-4  0.68
2002 Dunaief JL, King A, Esumi N, Eagen M, Dentchev T, Sung CH, Chen S, Zack DJ. Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo. Current Eye Research. 24: 392-6. PMID 12434308 DOI: 10.1076/ceyr.24.5.392.8524  0.68
2002 Swaroop A, Zack DJ. Transcriptome analysis of the retina. Genome Biology. 3: REVIEWS1022. PMID 12186651  0.68
2002 Sharma S, Chang JT, Della NG, Campochiaro PA, Zack DJ. Identification of novel bovine RPE and retinal genes by subtractive hybridization. Molecular Vision. 8: 251-8. PMID 12131876  0.68
2002 Mori K, Gehlbach P, Yamamoto S, Duh E, Zack DJ, Li Q, Berns KI, Raisler BJ, Hauswirth WW, Campochiaro PA. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Investigative Ophthalmology & Visual Science. 43: 1994-2000. PMID 12037010  0.68
2002 Chen S, Wang QL, Xu S, Liu I, Li LY, Wang Y, Zack DJ. Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy. Human Molecular Genetics. 11: 873-84. PMID 11971869  0.68
2002 Zhang K, Garibaldi DC, Li Y, Green WR, Zack DJ. Butterfly-shaped pattern dystrophy: a genetic, clinical, and histopathological report. Archives of Ophthalmology (Chicago, Ill. : 1960). 120: 485-90. PMID 11934323  0.68
2002 McKinnon SJ, Lehman DM, Kerrigan-Baumrind LA, Merges CA, Pease ME, Kerrigan DF, Ransom NL, Tahzib NG, Reitsamer HA, Levkovitch-Verbin H, Quigley HA, Zack DJ. Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension. Investigative Ophthalmology & Visual Science. 43: 1077-87. PMID 11923249  0.68
2002 Duh EJ, Yang HS, Suzuma I, Miyagi M, Youngman E, Mori K, Katai M, Yan L, Suzuma K, West K, Davarya S, Tong P, Gehlbach P, Pearlman J, Crabb JW, ... ... Zack DJ, et al. Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Investigative Ophthalmology & Visual Science. 43: 821-9. PMID 11867604  0.68
2002 Ohno-Matsui K, Hirose A, Yamamoto S, Saikia J, Okamoto N, Gehlbach P, Duh EJ, Hackett S, Chang M, Bok D, Zack DJ, Campochiaro PA. Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. The American Journal of Pathology. 160: 711-9. PMID 11839592 DOI: 10.1016/S0002-9440(10)64891-2  0.68
2001 Wahlin KJ, Adler R, Zack DJ, Campochiaro PA. Neurotrophic signaling in normal and degenerating rodent retinas. Experimental Eye Research. 73: 693-701. PMID 11747369 DOI: 10.1006/exer.2001.1078  0.68
2001 Yamada H, Yamada E, Ando A, Esumi N, Bora N, Saikia J, Sung CH, Zack DJ, Campochiaro PA. Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice. The American Journal of Pathology. 159: 1113-20. PMID 11549604 DOI: 10.1016/S0002-9440(10)61787-7  0.68
2001 Wilkie SE, Li Y, Deery EC, Newbold RJ, Garibaldi D, Bateman JB, Zhang H, Lin W, Zack DJ, Bhattacharya SS, Warren MJ, Hunt DM, Zhang K. Identification and functional consequences of a new mutation (E155G) in the gene for GCAP1 that causes autosomal dominant cone dystrophy. American Journal of Human Genetics. 69: 471-80. PMID 11484154 DOI: 10.1086/323265  0.68
2001 Mori K, Duh E, Gehlbach P, Ando A, Takahashi K, Pearlman J, Mori K, Yang HS, Zack DJ, Ettyreddy D, Brough DE, Wei LL, Campochiaro PA. Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. Journal of Cellular Physiology. 188: 253-63. PMID 11424092 DOI: 10.1002/jcp.1114  0.68
2001 Yan W, Jang GF, Haeseleer F, Esumi N, Chang J, Kerrigan M, Campochiaro M, Campochiaro P, Palczewski K, Zack DJ. Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium. Genomics. 72: 193-202. PMID 11401432 DOI: 10.1006/geno.2000.6476  0.68
2001 Tzekov RT, Liu Y, Sohocki MM, Zack DJ, Daiger SP, Heckenlively JR, Birch DG. Autosomal dominant retinal degeneration and bone loss in patients with a 12-bp deletion in the CRX gene. Investigative Ophthalmology & Visual Science. 42: 1319-27. PMID 11328746  0.68
2001 Shimura M, Yuan Y, Chang JT, Zhang S, Campochiaro PA, Zack DJ, Hughes BA. Expression and permeation properties of the K(+) channel Kir7.1 in the retinal pigment epithelium. The Journal of Physiology. 531: 329-46. PMID 11230507 DOI: 10.1111/j.1469-7793.2001.0329i.x  0.68
2001 Yamada E, Tobe T, Yamada H, Okamoto N, Zack DJ, Werb Z, Soloway PD, Campochiaro PA. TIMP-1 promotes VEGF-induced neovascularization in the retina. Histology and Histopathology. 16: 87-97. PMID 11193216  0.68
2001 Liu Y, Shen Y, Rest JS, Raymond PA, Zack DJ. Isolation and characterization of a zebrafish homologue of the cone rod homeobox gene. Investigative Ophthalmology & Visual Science. 42: 481-7. PMID 11157887  0.68
2001 Zhang K, Kniazeva M, Han M, Li W, Yu Z, Yang Z, Li Y, Metzker ML, Allikmets R, Zack DJ, Kakuk LE, Lagali PS, Wong PW, MacDonald IM, Sieving PA, et al. A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy. Nature Genetics. 27: 89-93. PMID 11138005 DOI: 10.1038/83817  0.68
2000 Chang MA, Horner JW, Conklin BR, DePinho RA, Bok D, Zack DJ. Tetracycline-inducible system for photoreceptor-specific gene expression. Investigative Ophthalmology & Visual Science. 41: 4281-7. PMID 11095627  0.68
2000 Chau KY, Munshi N, Keane-Myers A, Cheung-Chau KW, Tai AK, Manfioletti G, Dorey CK, Thanos D, Zack DJ, Ono SJ. The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7317-24. PMID 11007889  0.68
2000 Quigley HA, McKinnon SJ, Zack DJ, Pease ME, Kerrigan-Baumrind LA, Kerrigan DF, Mitchell RS. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Investigative Ophthalmology & Visual Science. 41: 3460-6. PMID 11006239  0.68
2000 Chau KY, Chen S, Zack DJ, Ono SJ. Functional domains of the cone-rod homeobox (CRX) transcription factor. The Journal of Biological Chemistry. 275: 37264-70. PMID 10984472 DOI: 10.1074/jbc.M002763200  0.68
2000 Seo MS, Okamoto N, Vinores MA, Vinores SA, Hackett SF, Yamada H, Yamada E, Derevjanik NL, LaRochelle W, Zack DJ, Campochiaro PA. Photoreceptor-specific expression of platelet-derived growth factor-B results in traction retinal detachment. The American Journal of Pathology. 157: 995-1005. PMID 10980138 DOI: 10.1016/S0002-9440(10)64612-3  0.68
2000 Yamada H, Yamada E, Kwak N, Ando A, Suzuki A, Esumi N, Zack DJ, Campochiaro PA. Cell injury unmasks a latent proangiogenic phenotype in mice with increased expression of FGF2 in the retina. Journal of Cellular Physiology. 185: 135-42. PMID 10942527 DOI: 10.1002/1097-4652(200010)185:1<135::AID-JCP13>3.0.CO;2-Y  0.68
2000 Mitton KP, Swain PK, Chen S, Xu S, Zack DJ, Swaroop A. The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation. The Journal of Biological Chemistry. 275: 29794-9. PMID 10887186 DOI: 10.1074/jbc.M003658200  0.68
2000 Zack DJ. Neurotrophic rescue of photoreceptors: are Müller cells the mediators of survival? Neuron. 26: 285-6. PMID 10839346  0.68
2000 Chen S, Zack DJ. Cloning and characterization of retinal transcription factors, using target site-based methodology. Methods in Enzymology. 316: 590-610. PMID 10800704  0.68
2000 Wahlin KJ, Campochiaro PA, Zack DJ, Adler R. Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors. Investigative Ophthalmology & Visual Science. 41: 927-36. PMID 10711715  0.68
2000 Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Investigative Ophthalmology & Visual Science. 41: 764-74. PMID 10711692  0.68
2000 Mathura JR, Jafari N, Chang JT, Hackett SF, Wahlin KJ, Della NG, Okamoto N, Zack DJ, Campochiaro PA. Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium. Investigative Ophthalmology & Visual Science. 41: 592-600. PMID 10670493  0.68
2000 Yamada H, Yamada E, Ando A, Seo MS, Esumi N, Okamoto N, Vinores M, LaRochelle W, Zack DJ, Campochiaro PA. Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy. The American Journal of Pathology. 156: 477-87. PMID 10666377 DOI: 10.1016/S0002-9440(10)64752-9  0.68
1999 Zack DJ, Dean M, Molday RS, Nathans J, Redmond TM, Stone EM, Swaroop A, Valle D, Weber BH. What can we learn about age-related macular degeneration from other retinal diseases? Molecular Vision. 5: 30. PMID 10562654  0.68
1999 Zack DJ. Birth and death in the retina: more related than we thought? Neuron. 23: 411-2. PMID 10433249 DOI: 10.1016/S0896-6273(00)80790-4  0.68
1999 Kniazeva MF, Chiang MF, Cutting GR, Zack DJ, Han M, Zhang K. Clinical and genetic studies of an autosomal dominant cone-rod dystrophy with features of Stargardt disease. Ophthalmic Genetics. 20: 71-81. PMID 10420191  0.68
1999 Gregerson DS, Torseth JW, McPherson SW, Roberts JP, Shinohara T, Zack DJ. Retinal expression of a neo-self antigen, beta-galactosidase, is not tolerogenic and creates a target for autoimmune uveoretinitis. Journal of Immunology (Baltimore, Md. : 1950). 163: 1073-80. PMID 10395707  0.68
1999 Fei Y, Matragoon S, Smith SB, Overbeek PA, Chen S, Zack DJ, Liou GI. Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo. Journal of Biochemistry. 125: 1189-99. PMID 10348924  0.68
1999 Kniazeva M, Chiang MF, Morgan B, Anduze AL, Zack DJ, Han M, Zhang K. A new locus for autosomal dominant stargardt-like disease maps to chromosome 4. American Journal of Human Genetics. 64: 1394-9. PMID 10205271 DOI: 10.1086/302377  0.68
1999 Chang JT, Esumi N, Moore K, Li Y, Zhang S, Chew C, Goodman B, Rattner A, Moody S, Stetten G, Campochiaro PA, Zack DJ. Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium. Human Molecular Genetics. 8: 575-83. PMID 10072424  0.68
1999 Swaroop A, Wang QL, Wu W, Cook J, Coats C, Xu S, Chen S, Zack DJ, Sieving PA. Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function. Human Molecular Genetics. 8: 299-305. PMID 9931337 DOI: 10.1093/hmg/8.2.299  0.68
1999 Ozaki H, Yu AY, Della N, Ozaki K, Luna JD, Yamada H, Hackett SF, Okamoto N, Zack DJ, Semenza GL, Campochiaro PA. Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression. Investigative Ophthalmology & Visual Science. 40: 182-9. PMID 9888442  0.68
1998 Jacobson SG, Cideciyan AV, Huang Y, Hanna DB, Freund CL, Affatigato LM, Carr RE, Zack DJ, Stone EM, McInnes RR. Retinal degenerations with truncation mutations in the cone-rod homeobox (CRX) gene. Investigative Ophthalmology & Visual Science. 39: 2417-26. PMID 9804150  0.68
1998 Swanson DA, Chang JT, Campochiaro PA, Zack DJ, Valle D. Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors. Investigative Ophthalmology & Visual Science. 39: 2085-94. PMID 9761287  0.68
1998 Ozaki H, Okamoto N, Ortega S, Chang M, Ozaki K, Sadda S, Vinores MA, Derevjanik N, Zack DJ, Basilico C, Campochiaro PA. Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization. The American Journal of Pathology. 153: 757-65. PMID 9736026 DOI: 10.1016/S0002-9440(10)65619-2  0.68
1998 Perez-Mediavilla LA, Chew C, Campochiaro PA, Nickells RW, Notario V, Zack DJ, Becerra SP. Sequence and expression analysis of bovine pigment epithelium-derived factor. Biochimica Et Biophysica Acta. 1398: 203-14. PMID 9689919 DOI: 10.1016/S0167-4781(98)00055-4  0.68
1998 Freund CL, Wang QL, Chen S, Muskat BL, Wiles CD, Sheffield VC, Jacobson SG, McInnes RR, Zack DJ, Stone EM. De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis. Nature Genetics. 18: 311-2. PMID 9537410 DOI: 10.1038/ng0498-311  0.68
1998 Kennedy BN, Goldflam S, Chang MA, Campochiaro P, Davis AA, Zack DJ, Crabb JW. Transcriptional regulation of cellular retinaldehyde-binding protein in the retinal pigment epithelium. A role for the photoreceptor consensus element. The Journal of Biological Chemistry. 273: 5591-8. PMID 9488687 DOI: 10.1074/jbc.273.10.5591  0.68
1998 Li X, Chen S, Wang Q, Zack DJ, Snyder SH, Borjigin J. A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX. Proceedings of the National Academy of Sciences of the United States of America. 95: 1876-81. PMID 9465110 DOI: 10.1073/pnas.95.4.1876  0.68
1998 Tobe T, Okamoto N, Vinores MA, Derevjanik NL, Vinores SA, Zack DJ, Campochiaro PA. Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors. Investigative Ophthalmology & Visual Science. 39: 180-8. PMID 9430560  0.68
1997 Swain PK, Chen S, Wang QL, Affatigato LM, Coats CL, Brady KD, Fishman GA, Jacobson SG, Swaroop A, Stone E, Sieving PA, Zack DJ. Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration. Neuron. 19: 1329-36. PMID 9427255 DOI: 10.1016/S0896-6273(00)80423-7  0.68
1997 Chen S, Wang QL, Nie Z, Sun H, Lennon G, Copeland NG, Gilbert DJ, Jenkins NA, Zack DJ. Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron. 19: 1017-30. PMID 9390516  0.68
1997 Chang JT, Milligan S, Li Y, Chew CE, Wiggs J, Copeland NG, Jenkins NA, Campochiaro PA, Hyde DR, Zack DJ. Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5881-90. PMID 9221785  0.68
1997 Mathura JR, Hackett SF, Ozaki H, Delia NG, Zack DJ, Campod-iaro PA. BMP-4 mRNA is decreased in the retinas of mice with ischemic retinopathy Investigative Ophthalmology and Visual Science. 38: S611.  0.68
1996 Nickells RW, Zack DJ. Apoptosis in ocular disease: a molecular overview. Ophthalmic Genetics. 17: 145-65. PMID 9010866 DOI: 10.3109/13816819609057889  0.68
1996 Kumar R, Chen S, Scheurer D, Wang QL, Duh E, Sung CH, Rehemtulla A, Swaroop A, Adler R, Zack DJ. The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures. The Journal of Biological Chemistry. 271: 29612-8. PMID 8939891 DOI: 10.1074/jbc.271.47.29612  0.68
1996 Chen S, Zack DJ. Ret 4, a positive acting rhodopsin regulatory element identified using a bovine retina in vitro transcription system. The Journal of Biological Chemistry. 271: 28549-57. PMID 8910484 DOI: 10.1074/jbc.271.45.28549  0.68
1996 Lee CH, Della NG, Chew CE, Zack DJ. Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6784-94. PMID 8824319  0.68
1996 Nie Z, Chen S, Kumar R, Zack DJ. RER, an evolutionarily conserved sequence upstream of the rhodopsin gene, has enhancer activity. The Journal of Biological Chemistry. 271: 2667-75. PMID 8576239 DOI: 10.1074/jbc.271.5.2667  0.68
1996 Rehemtulla A, Warwar R, Kumar R, Ji X, Zack DJ, Swaroop A. The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Proceedings of the National Academy of Sciences of the United States of America. 93: 191-5. PMID 8552602 DOI: 10.1073/pnas.93.1.191  0.68
1995 Nickells RW, Burgoyne CF, Quigley HA, Zack DJ. Cloning and characterization of rod opsin cDNA from the Old World monkey, Macaca fascicularis. Investigative Ophthalmology & Visual Science. 36: 72-82. PMID 7822161  0.68
1995 Quigley HA, Nickells RW, Kerrigan LA, Pease ME, Thibault DJ, Zack DJ. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Investigative Ophthalmology & Visual Science. 36: 774-86. PMID 7706025  0.68
1994 Chiu MI, Zack DJ, Wang Y, Nathans J. Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments. Genomics. 21: 440-3. PMID 8088841 DOI: 10.1006/geno.1994.1292  0.68
1992 Wang Y, Macke JP, Merbs SL, Zack DJ, Klaunberg B, Bennett J, Gearhart J, Nathans J. A locus control region adjacent to the human red and green visual pigment genes. Neuron. 9: 429-40. PMID 1524826 DOI: 10.1016/0896-6273(92)90181-C  0.68
1991 Shin SU, DePinho R, Zack DJ, Rudikoff S, Scharff MD. Instability of immunoglobulin genes in S107 cell line. Somatic Cell and Molecular Genetics. 17: 259-76. PMID 1904631 DOI: 10.1007/BF01232821  0.68
1991 Zack DJ, Bennett J, Wang Y, Davenport C, Klaunberg B, Gearhart J, Nathans J. Unusual topography of bovine rhodopsin promoter-lacZ fusion gene expression in transgenic mouse retinas. Neuron. 6: 187-99. PMID 1899580 DOI: 10.1016/0896-6273(91)90355-4  0.68
1987 Giusti AM, Chien NC, Zack DJ, Shin SU, Scharff MD. Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region. Proceedings of the National Academy of Sciences of the United States of America. 84: 2926-30. PMID 3106981 DOI: 10.1073/pnas.84.9.2926  0.68
1983 Teillaud JL, Desaymard C, Giusti AM, Haseltine B, Pollock RR, Yelton DE, Zack DJ, Scharff MD. Monoclonal antibodies reveal the structural basis of antibody diversity. Science (New York, N.Y.). 222: 721-6. PMID 6356353  0.4
1981 Zack DJ, Morrison SL, Cook WD, Dackowski W, Scharff MD. Somatically generated mouse myeloma variants synthesizing IgA half-molecules. The Journal of Experimental Medicine. 154: 1554-69. PMID 7299348  0.68
1980 Cook WD, Rudikoff S, Giusti AM, Zack DJ, Kelly T, Scharff MD. Antigen binding variants of the S107 mouse myeloma cell line. Progress in Clinical and Biological Research. 42: 217-30. PMID 6771769  0.68
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